CN107488717A - Human genome mutational load capture probe and application are detected based on high-flux sequence - Google Patents

Abstract

The present invention relates to field of gene detection, and in particular to detects human genome mutational load capture probe and application based on high-flux sequence.Capture probe provided by the invention based on high-flux sequence detection human genome mutational load, the capture probe include capture probe 1, capture probe 2 and capture probe 3, the sequence such as SEQ ID NO of the capture probe 1:Shown in 1~275, the sequence such as SEQ ID NO of the capture probe 2:Shown in 276~550, the sequence such as SEQ ID NO of the capture probe 3:Shown in 551~825, the probe of the designed synthesis of the present invention can capture encoded exon region and the extron introne handover region of human genome target area, reduce non-specific capture, while hybridization temperature is homogeneous.Using the capture probe capture human genome target area of the present invention, sequencing depth is significantly improved, makes mutational load testing result and WES that there is high correlation, and testing cost and sequencing data amount is greatly reduced, shorten single sample analysis time.

Description

Human genome mutational load capture probe and application are detected based on high-flux sequence

Technical field

The present invention relates to gene field, and in particular to is visited based on high-flux sequence detection human genome mutational load capture Pin and application.

Background technology

In recent years, with the related discipline such as molecular biology, immunology, biochemistry and clinical medicine, laboratory medicine Continuous development so that tumor immunotherapy medicine shows wide application prospect.More and more immune tumour medicine quilt Develop and be applied to clinic, more patients is benefited.But significant individual occurs in clinical practice for immune tumour medicine Difference, different patients have different drug susceptibilities to same medicine.Such as in colorectal cancer patients, only about 5% is left Right patient is to immunodepressant class medicaments insensitive, and remaining patient responds after medication without preferable medication.This phenomenon Also it is observed in other cancer kinds, such as lung cancer, melanoma, carcinoma of urinary bladder, liver cancer.The individual difference of patient's curative effect expedites the emergence of The continuous development of accurate medical procedure including high throughput sequencing technologies.

Accurate medical treatment be based on Personalized medicine, with genomic sequencing technique rapid advances and biological information with The cross-application of big data science and the new medical concept and medical model to grow up.Its essence is by genome, egg The omics technologies such as white matter group and medical science cutting edge technology, point of biomarker is carried out for large sample crowd and specified disease type Analysis and identification, checking and application, so as to the reason for accurately searching out disease and the target spot for the treatment of, and to a kind of disease different conditions Precise classification is carried out with process, final realize carries out the personalized purpose precisely treated for disease and particular patient, improve disease The benefit of sick diagnosis and treatment and prevention.

High throughput sequencing technologies to hundreds of thousands to millions of DNA moleculars can once carry out sequencings and general parallel Long shorter grade is read as mark.High throughput sequencing technologies are the changes to tradition sequencing revolution, once to hundreds of thousands to several Million DNA molecular carries out sequencing, and high throughput sequencing technologies bonding probes capture technique can determine within a short period of time Human genome target area sequence, quick obtaining target area sequence information is set to become a reality.With high-flux sequence skill The development of art and capture technique, mutational load have been applied as a kind of novel tumor label in clinic.It data show, In carcinoma of urinary bladder and Patients with Non-small-cell Lung, the mutational load of medication response group patient has apparently higher than non-response group The patient of high mutational load is considerably longer than low mutational load patient its mean survival time (MST).

The two very important high-throughput techniques currently established：Genetic chip and second generation sequencing technologies.Both skills Art is further combined with just generating a kind of new solution：Target sequence captures sequencing technologies.Target sequence capture refers to lead to Cross the specific region of some way selectively separation or enrichment genome.A kind of important method is according to nucleic acid molecules Base complementrity Hybridization principle designs the probe sequence complementary with purpose region, and different according to state during hybridization, and target sequence is caught Solid-phase hybridization method and solution hybridization method can be divided into by obtaining.Solution hybridization is the target DNA fragments and with life by the solution Thing element label probe direct cross, then target DNA fragments are made to be anchored on Avidin by biotin-labeled pentylamine reaction On microballon.Non-targeted DNA is washed away, after elution, the DNA of enrichment is used to be sequenced.Compared to solid-phase hybridization, solution hybridization has operation Simplicity, it is easy to the advantages that automation.

Common mutational load detection mode is full sequencing of extron group (WES, whole exome sequencing).Should Method testing cost is high, and data volume is big, analysis time length.To make mutational load be preferably applied for lesion detection field, this hair It is bright by screening the multiple key areas of mutational load, pointedly design efficient capture probe, significantly improve sequencing depth, make Mutational load testing result has high correlation with WES, and testing cost and sequencing data amount is greatly reduced, and shortens single sample This analysis time.

The content of the invention

Technical problem solved by the invention is：Existing mutational load detection mode is full sequencing of extron group, described Method testing cost is high, and data volume is big, analysis time length.

In view of the above-mentioned problems, the invention provides a kind of capture spy based on high flux detection human genome mutational load Pin, the capture probe include capture probe 1, capture probe 2 and capture probe 3, and the capture probe capture human genome closes Key range, sequencing depth is significantly improved, the testing result and WES for making mutational load have high correlation, and inspection is greatly reduced Cost and sequencing data amount are surveyed, shortens the analysis time of single sample.

The invention provides a kind of method based on high flux detection human genome mutational load, it includes following step：

(1) the genomic DNA double-strandednucleic acid in blood and tissue samples is extracted；

(2) the DNA double chain nucleic acid denaturation of step (1) handles to obtain to DNA is single-stranded, and usage right requires that 1-5 is any The DNA described in capture probe capture described in is single-stranded；

(3) the single-stranded progress higher level's sequencings of DNA captured step (2), obtain the nucleotide sequence in blood and tissue samples；

(4) nucleotide sequence obtained by step (3) is subjected to automatic business processing, removes variation information and background signal, meter The variant sites number in tissue samples is calculated, according to formula mutational load=sample measures region variation sum/sample measures area Domain size obtains mutational load number.

Specifically, the present invention proposes following technical scheme.

A kind of capture probe based on high-flux sequence detection human genome mutational load, the capture probe include capture and visited Pin 1, capture probe 2 and capture probe 3, the sequence such as SEQ ID NO of the capture probe 1:Shown in 1~275, the capture probe 2 sequence such as SEQ ID NO:Shown in 276~550, the sequence such as SEQ ID NO of the capture probe 3:Shown in 551~825.

Preferably, for described capture probe, wherein, the capture probe includes 21108 probes, preferably comprises 10333 probes.

Preferably, for described capture probe, wherein, the Tm values of the capture probe are 65-75 DEG C.

Preferably, for described capture probe, wherein, the concentration of the capture probe is 0.1PM~6PM, preferably 1.5PM.

Preferably, for described capture probe, wherein, the area of the capture probe covering gene group 0.8Mb-2.4Mb Domain, preferably 0.8Mb-1.2Mb regions, more preferably 1.2Mb regions.

A kind of capture probe, its application in human genome mutational load is detected based on high-flux sequence.

A kind of method based on high-flux sequence detection human genome mutational load, it includes following step：

(1) the genomic DNA double-strandednucleic acid in blood and tissue samples is extracted；

(2) the DNA double chain nucleic acid denaturation of step (1) handles to obtain to DNA is single-stranded, and usage right requires that 1-5 is any The DNA described in capture probe capture described in is single-stranded；

(3) the single-stranded progress higher level's sequencings of DNA captured step (2), obtain the nucleotide sequence in blood and tissue samples；

(4) nucleotide sequence obtained by step (3) is subjected to automatic business processing, removes variation information and background signal, meter The variant sites number in tissue samples is calculated, according to formula mutational load=sample measures region variation sum/sample measures area Domain size obtains mutational load number.

Preferably, for the method that human genome mutational load is detected based on high-flux sequence, wherein, in step (1) in, fragmentation processing is carried out after genomic DNA double-strandednucleic acid is extracted, it is 100-1000bp to obtain fragment length, preferably , fragment length 100-500bp, it is furthermore preferred that fragment length is 200-300bp.

Preferably, for the method that human genome mutational load is detected based on high-flux sequence, wherein, in step (4) in, the mensuration region of the sample is 0.8-2.4Mb, preferably 0.8-1.2Mb, more preferably 1.2Mb.

A kind of kit based on high-flux sequence detection human genome mutational load, wherein, the kit is included and caught Obtain probe and selected from end repair enzyme, end repair reaction buffer, DNA ligase, coupled reaction buffer solution, containing molecular label It is joint, amplified library primer, PCR premixed liquids, tab closure agent, DNA sealers, hybridization buffer, hybridization enhancers, magnetic bead washing lotion, miscellaneous Hand over one or more reagents of washing lotion, capture library PCR primer, quality-control product I and II, nucleic acid purification magnetic bead and streptavidin magnetic bead.

Preferably, for the kit based on high-flux sequence detection human genome mutational load, wherein, the kit Reaction buffer, DNA ligase, coupled reaction buffer solution, mark containing molecule are repaired comprising capture probe, end repair enzyme, end Joint, amplified library primer, PCR premixed liquids, tab closure agent, DNA sealers, hybridization buffer, hybridization enhancers, the magnetic of label Pearl washing lotion, hybridization washing lotion, capture library PCR primer, quality-control product I and II, nucleic acid purification magnetic bead and streptavidin magnetic bead.

Beneficial effect acquired by the present invention is：Capture probe designed by the present invention, capture the genome of human genome The encoded exon region of target area and extron introne handover region, reduce non-specific capture, while hybridization temperature Homogeneous, capture probe of the invention efficiently captures human genome key area, significantly improves sequencing depth, makes mutational load Testing result has high correlation with WES, and testing cost and sequencing data amount is greatly reduced, shortens single sample analysis time.

Brief description of the drawings

Fig. 1 is the testing result and the testing result correlation of WES mutational load number of the mutational load number of embodiment six Schematic diagram.

Embodiment

Fig. 1 is the testing result and the testing result correlation of WES mutational load number of the mutational load number of embodiment six Schematic diagram, it can be seen that the mutational load number of the testing result of the mutational load number in 2.4M regions and full extron The uniformity of testing result can reach 0.7949 (R²), testing result and the full extron of the mutational load number in 1.2M regions The uniformity of testing result of mutational load number can reach 0.9135 (R²), the detection knot of the mutational load number in 0.8M regions Fruit and the uniformity of the testing result of the mutational load number of full extron can reach 0.9083 (R²), illustrate to catch using the present invention Obtain the target area that probe capture human genome mutational load, testing result obtained from entering and the inspection of full extron sequencing It is higher to survey result uniformity, but testing cost and sequencing data amount is greatly reduced, shortens single sample analysis time.

The term " hybrid capture " of the present invention refers to be hybridized by complementary dna sequence and targeting DNA sequence dna, to be measured Nucleic acid carries out the method for targetting enrichment.

Term " Tm values " refers to DNA solution temperatures, and ultraviolet absorption value reaches during referring to the double-spiral structure thermal denaturation DNA To 1/2 temperature of maximum.

Term " mutational load " refers to the mutation number in unit encoding area on genome.

Term " full sequencing of extron group (WES) " refers to that high pass will be carried out after the full exon 1 domain dna enrichment of full-length genome Measure the genome analytical method of sequence.

Term " genomic library " refers to the DNA fragmentation gram that certain biological full gene group DNA is cut into certain length The set of grand formation, amplification, Sanger sequencings or new-generation sequencing available for downstream.

Term " new-generation sequencing technology " is also known as large-scale parallel sequencing massivelyparallel sequencing (MPS), refer to the principle using " in synthesis be sequenced ", for hundreds of thousands to millions of DNA moleculars while carry out parallel survey Sequence react, then by the raw image data obtained by bioinformatic analysis or electrochemical signals, finally give and treat test sample The sequencing technologies of the information such as the nucleotide sequence or copy number of product, also known as high-flux sequence, deep sequencing, the sequencing of two generations etc..It is high The base program of flux sequencing is that DNA to be measured is broken into small fragment at random, is repaired through end, the step such as jointing sequence, PCR It is rapid to carry out library enlarging, finally it is measured using the sequenator such as Illumina, Ion Torrent.

As described above, the invention provides a kind of capture spy based on high-flux sequence detection human genome mutational load Pin, the capture probe include capture probe 1, capture probe 2 and capture probe 3, the sequence such as SEQ ID of the capture probe NO:Shown in 1~275, the sequence such as SEQ ID NO of capture probe 2:Shown in 276~550, the sequence such as SEQ ID of capture probe 3 NO:Shown in 551~825.

In the preferred embodiments of the disclosure, the capture probe is the mixture of a plurality of probe, described a plurality of Probe captures the different target area of human genome respectively, preferably captures the encoded exon region of human genome target area And extron introne handover region.

In a kind of preferred embodiment of the present invention, a plurality of probe of the capture probe is mixed by same ratio Be combined, and there is mark on every probe, preferably biotin labeling, the working concentration of the capture probe for 0.1~ 6PM, preferably 1.5PM, PM be picomole/liter.

The invention provides a kind of method based on high-flux sequence detection human genome mutational load, it includes following step：

(1) the genomic DNA double-strandednucleic acid in blood and tissue samples is extracted；

(2) the DNA double chain nucleic acid denaturation of step (1) handles to obtain to DNA is single-stranded, and usage right requires that 1-5 is any The DNA described in capture probe capture described in is single-stranded；

(3) the single-stranded progress higher level's sequencings of DNA captured step (2), obtain the nucleotide sequence in blood and tissue samples；

(4) nucleotide sequence obtained by step (3) is subjected to automatic business processing, removes variation information and background signal, meter The variant sites number in tissue samples is calculated, according to formula mutational load=sample measures region variation sum/sample measures area Domain size obtains mutational load number.

In the preferred embodiments of the disclosure, in step (1), the DNA double chain nucleic acid of extraction carries out fragmentation Processing, it is 100-1000bp to obtain fragment length, it is preferred that fragment length 100-500bp, it is furthermore preferred that fragment length is 200-300bp。

In the preferred embodiments of the disclosure, in step (4), the mensuration region 0.8-2.4Mb of the sample, Preferably 0.8-1.2Mb, more preferably 1.2Mb.

The invention provides a kind of kit based on high-flux sequence detection human genome mutational load, it includes capture and visited Pin and selected from end repair enzyme, end repair reaction buffer, DNA ligase, coupled reaction buffer solution, connecing containing molecular label It is head, amplified library primer, PCR premixed liquids, tab closure agent, DNA sealers, hybridization buffer, hybridization enhancers, magnetic bead washing lotion, miscellaneous Hand over one or more reagents of washing lotion, capture library PCR primer, quality-control product I and II, nucleic acid purification magnetic bead and streptavidin magnetic bead.

It is of the invention negative based on high-flux sequence detection human genome mutation in the preferred embodiments of the disclosure The kit of lotus, comprising capture probe, end repair enzyme, end repair reaction buffer, DNA ligase, coupled reaction buffer solution, Joint containing molecular label, amplified library primer, PCR premixed liquids, tab closure agent, DNA sealers, hybridization buffer, hybridization increase Strong agent, magnetic bead washing lotion, hybridization washing lotion, capture library PCR primer, quality-control product I and II, nucleic acid purification magnetic bead and streptavidin magnetic bead.

The present invention targetedly designs synthetic capture probe, institute according to multiple key areas of human genome mutational load Capture probe capture human genome target area is stated, significantly improves sequencing depth, the testing result and WES for making mutational load have There is high correlation, testing cost and sequencing data amount is greatly reduced, shorten single sample analysis time.

Below to the raw material used in the present embodiment and the manufacturer of equipment, and the equipment that uses of product analysis and analysis Method is described as follows, wherein described chemical substance do not indicate be conventional reagent chemical pure rank.Wherein, it is real The information for applying the experimental facilities used in example is as shown in table 1.

The information of experimental facilities used in the present invention of table 1

Equipment	Model	Producer
			NextSeq500 sequenators	NextSeq500	Illumina companies of the U.S.
Centrifuge	H2100R/CT-15RT	Hunan Hunan instrument
			PCR amplification instrument	S1000	Bio Rad Laboratories
Centrifuge tube	LoBind	German eppendorf companies

The human genome mutational load of embodiment one detects the preparation of quality-control product

(1) two plants of conventional stablizing are obtained from ATCC purchases and passes on human tumor cell line HCC1937 and HCT-15；

(2) this two plants of human tumor cell lines are cultivated using hyclone culture medium (being provided by Thermo Fisher companies), Condition of culture：37 DEG C of constant temperature, 5%CO₂, humidity 50%；Culture is passed on when reaching culture dish area 80-90% to cell density, Exponential phase cells are collected, and 800-1000r/min centrifugation takes precipitation, extracts the genome of each cell line respectively DNA, and cross post purifying, elution；

(3) genomic DNA of each cell line after purification is buffered with Tris-EDTA buffer solution respectively Liquid is diluted to 100 ± 5ng/ μ L, and outward appearance is transparency liquid, is visible by naked eyes impurity, and purity is 1.9 ＞ OD260/280 ＞ 1.7, Obtain quality-control product raw material DNA；

(4) genomic DNA of each cell line is sequenced with WES PCR sequencing PCRs, confirmed heterozygosis and homozygous variation Site calculates site as mutational load, and empirical tests contain 26 variant sites altogether, and theoretical mutations load is 22；

(5) by the quality-control product raw material DNA of two kinds of cell line HCC1937, HCT-15 according to 1：1 volume ratio is uniformly mixed Close packing and be used as quality-control product I, -20 DEG C of preservations；

(6) using cell line HCT-15 quality-control product raw material DNA packing as quality-control product II, -20 DEG C of preservations；

(7) quality-control product I and the collocation of quality-control product II use when using, and quality-control product I is used as simulated tissue sample DNA, quality-control product II as simulation whole blood sample DNA.

The 0.8Mb mutational load assessment areas capture probe of embodiment two designs

Human genome mutational load key area is chosen, a plurality of capture probe is designed and synthesized according to key area, it is described Key area is as shown in table 2；The capture probe implementation sequence example such as SEQ ID NO:Shown in 1-275；The capture probe length Spend for 120bp, the capture probe is end to end, covers 0.8Mb key areas exon 1 and extron introne handover region；Institute There is probe to be respectively provided with biotin labeling, the capture probe is 6686 probe mixtures, and the design method of the capture probe is：

(1) mankind full-length genome standard sequence HG19 (the Human Genome provided according to common data website NCBI 19) exon region and extron introne handover region of each target area (being shown in Table 2) are determined；

(2) using the exon region in regional and the first extron of extron introne handover region as starting, root Design capture probe according to standard sequence HG19, probe length be 120bp (if any extron or to its end less than 120bp situations, Extron introne cross-connecting area is then extended to, guarantee probe length is 120bp), then region determines that then probe design has unique Property；Such as by taking No. 1 region as an example, No. 1 region is located at the position of the chromosome 15571265~15586951 of people 1, the region total length For 15686bp, exon region and extron introne handover region total length in the region are inquired about according to standard sequence HG19 For 10236bp, probe 93 is designed altogether；

(3) design probe is synthesized, while be marked with biotin；

The key area of table 2

The 1.2Mb mutational load assessment areas capture probe of embodiment three designs

Human genome mutational load key area is chosen, more capture probes are designed and synthesized according to key area；The pass Key range is as shown in table 3；The capture probe implementation sequence example such as SEQ ID NO:Shown in 276-550；The capture probe Length is 120bp；The capture probe is end to end, covers 1.2Mb key areas exon 1 and the handing-over of extron introne Region；All probes are respectively provided with biotin labeling；The capture probe is 10333 probe mixtures；The capture probe is set Meter method is identical with embodiment two.

The key area of table 3

Example IV 2.4Mb mutational load assessment areas capture probe designs

Human genome mutational load key area is chosen, more capture probes are designed and synthesized according to key area；The pass Key range is as shown in table 3；The capture probe implementation sequence example such as SEQ ID NO:Shown in 551-825；The capture probe Length is 120bp；The capture probe is end to end, covers 2.4Mb key areas exon 1 and the handing-over of extron introne Region；All probes are respectively provided with biotin labeling；The capture probe is 21108 probe mixtures；The capture probe is set Meter method is identical with embodiment two.

The key area of table 4

Embodiment five：The preparation of human genome mutational load detection kit

(1) capture probe of target area different shown in embodiment two, embodiment three or example IV is designed and synthesized.

(2) design capture probe is pressed into identical mass mixing together, and mixture is diluted to working concentration 1.5PM (PM=picomoles/liter), -20 DEG C of preservations.

(3) quality-control product obtained in capture probe mixture and embodiment one is dispensed respectively.

(4) specification, outer packing, assembling sealing are prepared.

(5) wherein the dosage of capture probe mixture is reacted for 6 μ L/3,12 μ L/6 reactions, 24 μ L/12 reactions, 48 μ L/24 Reaction；The dosage of quality-control product is reacted for 5 μ L/.

The preparation of the human genome mutational load detection kit of embodiment six

(1) capture probe of target area different shown in embodiment two, embodiment three or example IV is designed and synthesized.

(2) design capture probe is pressed into identical mass mixing together, and mixture is diluted to working concentration 1.5PM (PM=picomoles/liter), -20 DEG C of preservations.

(3) quality-control product obtained in capture probe mixture, embodiment one, end repair enzyme, end are repaired into reaction to delay Fliud flushing, DNA ligase, coupled reaction buffer solution, the joint containing molecular label, amplified library primer, PCR premixed liquids, joint envelope Close agent, DNA sealers, hybridization buffer, hybridization enhancers, magnetic bead washing lotion, hybridization washing lotion, capture library PCR primer, quality-control product I and II, nucleic acid purification magnetic bead and streptavidin magnetic bead dispense respectively.

(4) specification, outer packing, assembling sealing are prepared.

(5) wherein the dosage of capture probe mixture is reacted for 6 μ L/3,12 μ L/6 reactions, 24 μ L/12 reactions, 48 μ L/24 Reaction；The dosage of quality-control product is reacted for 5 μ L/.

The detection of the human genome mutational load of embodiment seven

Instrument used in sequencing is NextSeq500 in the present embodiment.

Use following methods and captured respectively with the capture probe of the embodiment of the present invention 2, the capture probe of embodiment 3 and embodiment 4 Probe carries out mutational load detection to sample.The preparation method of quality-control product is the same as embodiment 1.

1. extraction and the fragmentation of sample：Nucleic acid extraction agent kit (tall building is used from 9 pairs of blood samples and tissue samples Men Aide biological medicines Science and Technology Ltd.) human gene group DNA is extracted, quality-control product directly uses, and without extraction, takes respectively 600ng everyone genomic samples and quality-control product, less than 50 μ l PCR-grade water polishings to 50 μ l, carry out from The heart, then solution is transferred completely into micro-pipe, fragment is carried out on Covaris S2 instruments (being purchased from Covaris companies of the U.S.) Change, obtain the mixture of 200-300bp DNA double chain nucleic acid fragment, and take the sample of 5 μ l fragmentations to carry out Ago-Gel electricity Swimming；Quality-control product is operated according to sample identical method.

2. construction of gene library

1) end is repaired and connected with joint：In 0.2mlPCR reaction tubes, 400ng double stranded nucleic acid fragments sample after purification is added This, with PCR-grade water polishings to 50 μ l, is then respectively adding 3 μ l ends and repairs enzymatic mixture (containing 5~40U/ μ L ends Hold the solution of repair enzyme) and 7 μ l ends reparation reaction buffer, 30min is incubated after centrifugation at 20 DEG C, is then protected at 65 DEG C Warm 30min, carry out end reparation；2 μ l joints (label containing index), 10 μ l DNA ligases, 30 μ l are separately added into after centrifugation to connect Connect reaction buffer and 8 μ l PCR-grade water carry out joint connection.The joint sequence is：

AATGATACGGCGACCACCGAGATCTACACNNNNNNNNNACACTCTTTCCCTACACGACGCTCTTCCGAT CT

GATCGGAAGAGCACACGTCTGAACTCCAGTCACATCACG-GAGTGGA- ATCTCGTATGCCGTCTTCTGCTTG

2) purify：After the product that joint connects is centrifuged, it is transferred in 1.5ml centrifuge tube, adds 99 μ l nucleic acid Magnetic bead is purified, is centrifuged, supernatant is abandoned in suction, is then added the ethanol of 200 μ l 80%, is inhaled after standing 1min and abandon supernatant, repeated washing Once, then into pipe 22 μ lNuclease-free water are added magnetic bead is resuspended, be stored at room temperature, take the μ l to 0.2ml of supernatant 20 PCR reaction tubes in it is standby；

3. gene library expands and purifying：25ul 2 is separately added into the PCR reaction tubes of the 0.2ml equipped with 20 μ l supernatants × PCR premixed liquids (containing 1~50U/ μ L Taq archaeal dna polymerases amplification reaction solution) and 5 μ l amplimers；

Expanded in PCR instrument by following programs：98 DEG C, 1min；98 DEG C of denaturation 15s, 60 DEG C of annealing 30s, 72 DEG C are prolonged Stretch 30s, 7-9 circulation of coamplification；Final 72 DEG C of extensions 1min, is saved backup at 4 DEG C；

The product of amplification is transferred completely into 1.5ml centrifuge tubes, then adds 45 μ l nucleic acid purification magnetic beads, centrifugation suction is abandoned Supernatant, the ethanol of 200 μ l 80% is added, is inhaled after standing 30s and abandons supernatant, repeated washing once, then adds 52 μ l Nuclease- Magnetic bead is resuspended in free water, is stored at room temperature 5min, takes 50 μ l supernatants standby into centrifuge tube；And take 2 μ l amplified production DNA Amplified production concentration is detected using Qubit fluorescent quantitation instruments (being purchased from Life Invitrogen companies of the U.S.)；

4. gene library captures

1) hybridize：Every 8 libraries, which are blended in a sample cell, carries out hybrid capture, is finally blended in one less than 8 Hybrid capture is carried out in individual sample cell, library is mixed according to quantity in 1.5mL LoBind centrifuge tubes turns into a sample cell, blood Liquid sample dosage is not less than 125ng, and sample cell total amount is no more than 1 μ g.2 μ l tab closures agent and 5 μ lDNA are added into sample cell Sealer, concussion are mixed, are freeze-dried under vacuum after of short duration centrifugation.8.5 μ l hybridization buffers (2 ×) are added (containing 0.1M~20M NaCl, NaH₂PO₄The solution of composition), 2.7 μ l hybridization enhancers (NaCl containing 0.1M~20M, ficoll composition it is molten Liquid) and 3.8 μ l PCR-grade water, concussion mixes, and after of short duration centrifugation, is stored at room temperature that 5min weights are molten, by liquid of the weight after molten Body is transferred completely into 0.2ml PCR reaction tubes, and 10 minutes are incubated at 95 DEG C and takes out PCR reaction tubes, is added and is divided after of short duration centrifugation The capture probe mixture of 2 μ L embodiments two, three and four acquisition is not added, and concussion mixes 3-5s, in 65 DEG C of guarantors after of short duration centrifugation Warm 4h, hot lid temperature are 75 DEG C.

Wherein, the concentration of the probe mixture is 1.5PM.

Wherein, the sequence of the probe mixture in embodiment two such as SEQ ID NO:Shown in 1~275,

The sequence of probe mixture in embodiment three such as SEQ ID NO:Shown in 276~550,

The sequence of probe mixture in example IV such as SEQ ID NO:Shown in 551~825；

2) it is enriched with：Added after Streptavidin MagneSphere is washed 1 times of volume magnetic bead washing lotion (NaCl containing 0.1M~25M, The solution of Tris compositions), vibration is dispensed into different 0.2ml PCR reaction tubes after being resuspended by every μ l of pipe 100；In 1) PCR reaction tubes take out, and whole hybrid products will be transferred to the PCR reaction tubes containing Streptavidin MagneSphere after of short duration centrifugation In, fully suspend after 65 DEG C of incubation 45min in PCR instrument, during which inhaled every 12min and play mixing once.After incubation terminates, often manage 1 × washing lotion 1 (solution of NaCl, SDS composition containing 0.1M~25M) of 100 μ l, 65 DEG C of preheatings is added, whole suspensions are turned Move in 1.5mL LoBind centrifuge tubes, concussion is mixed, and is transferred to after of short duration centrifugation on magnetic frame and stands 20s, and supernatant is abandoned in suction.So 1 × hybridization washing lotion (NaCl, SDS, Na containing 0.1M~25M of 200 μ l, 65 DEG C of preheatings are added afterwards₂HPO₄The solution of composition) shake Mixing is swung, 65 DEG C of incubation 5min, are transferred on magnetic frame and stand 20s after of short duration centrifugation, and supernatant is abandoned in suction.Repeat this step once. And 18 μ lNuclease-free water are added after fully being eluted with magnetic bead washing lotion, 0.2ml PCR reactions are transferred to after concussion Guan Zhong；

5. capture amplified library and purifying

1) amplified library is captured：25 μ 2 × PCR of l premixed liquids and capture library are separately added into above-mentioned PCR reaction tubes Each 2.5 μ L of PCR primer, after mixing centrifugation, enter performing PCR amplification by following programs：95 DEG C, 3min；98 DEG C of denaturation 20s, 60 DEG C are moved back Fiery 30s, 72 DEG C of extension 30s, 10 circulations of coamplification, final 72 DEG C of extensions 1min, saved backup at 4 DEG C；

2) purify：After PCR reaction tubes are centrifuged, product is fully transferred in centrifuge tube, adds 75 μ l nucleic acid purification magnetic Pearl, of short duration centrifugation after 10min is stood, is transferred on magnetic frame and stands 1min, supernatant is abandoned in suction.The ethanol of 200 μ l 80% is added, Supernatant is abandoned in suction after standing 30s, and once, uncap to dry to dripless remains repeated washing.Then 21.6 μ l Nuclease- are added Magnetic bead is resuspended in free water, is stored at room temperature 5min, is transferred on magnetic frame and stands 1min, takes 20 μ l supernatants standby into centrifuge tube With；And the quality-control product DNA of 2 μ L capture libraries or capture is taken to use Qubit fluorescent quantitation instruments detection amplified production concentration；

6. sequencing result and analysis

(1) it is sequenced：Above-mentioned resulting amplified production is subjected to upper machine according to sequencing instrument and matched reagent operation instruction Sequencing, average effective overburden depth：≥300×；

(2) data process＆analysis：

1) compare

After obtaining raw sequencing data, compared with reference data storehouse, the data after comparison contain included in sample it is all The information that makes a variation and background signal.Processing is synchronously compared in the sequencing result of blood sample and tissue samples.

2) embryonal system variation removes

The variant sites information that the variant sites information obtained in blood sample is obtained from tissue removes, and detects body Cytometaplasia site.

3) background signal removes

Testing result is subjected to automated analysis, for variation reads numbers, site of the abundance less than threshold value and false positive Variant sites point is removed.

4) removal of mononucleotide polymorphism site

Remove the mononucleotide polymorphism site in public database.

5) mutational load is calculated

Variant sites number in computation organization's sample, mutation is calculated using following calculation formula according to variation number and born Lotus：

Mutational load=sample measures region variation sum/sample measures area size (Mb)

6) mutational load linear dependence and mapping analysis are calculated

According to variety classes probe mutational load testing result, with simple linear regression analysis method calculate respectively its with The linear dependence of WES results, and make Discrete point analysis.

Testing result is as follows：

The clinical sample mutational load testing result of table 5

Sample number	WES measurement results	The probe assay result of embodiment two	The probe assay result of embodiment three	Example IV probe assay result
					1	3	4	5	5
2	3	4	4	6
					3	4	7	7	7
4	2	5	5	5
					5	3	7	6	6
6	3	5	5	5
					7	8	12	14	10
8	3	5	4	5
					9	3	7	6	5

The mutational load testing result of clinical sample is as shown in table 5, and the probe assay result of embodiment two and WES results are linear Correlation is R²=0.7949, the probe assay result of embodiment three and WES results linear dependence are R²=0.9135, embodiment Four probe assay results and WES results linear dependence are R²=0.9083, corresponding scatter diagram (R as shown in Figure 1²>=0.5 thinks With stronger linear dependence).

Embodiment eight：Repeatability experiment

Preparation method according to embodiment one prepares quality-control product I and quality-control product II.

Using the capture probe mixture of embodiment three three batches of kits, lot number are produced according to the preparation method of embodiment five Respectively 20170420,20170421,20170422.

Detection method according to embodiment six is carried out to quality-control product I and the detection of the mutational load of quality-control product II.Same batch examination Agent box 20170420, quality-control product I and quality-control product II each 3 time are detected, testing result is shown in Table 6.Different batches kit 20170420, 20170421,20170422, quality-control product I and quality-control product II each 3 time are detected, testing result is shown in Table 7.

6 batches of interior differences of table

Lot number	Sample names	Mutational load theoretical value	Mutational load detected value
				20170420	I/quality-control product of quality-control product II	22	22
20170420	I/quality-control product of quality-control product II	22	22
				20170420	I/quality-control product of quality-control product II	22	22

The differences between batches of table 7

Testing result：Kit repeatability meets to require.

Embodiment nine：With WES comparative analyses

The probe sample mutational load detection method of 6 preferred embodiment of embodiment 3 is entered with WES mutational load detection methods Row comparative analysis.Sequencing data amount and average effective sequencing depth correlation are shown in Table 8, are shown in Table 9 with WES Cost comparisons.

The present invention of table 8 and WES data volumes and sequencing depth correlation

As can be seen from the above table, the present invention designs synthetic capture probe for the key area of human genome, by synthesis When capture probe is applied to tumor area measure human genome mutational load number, compared with WES measure mutational load numbers are carried out, this Invention data volume used is less, and effective depth high sensitivity is high.

The present invention of table 9 and WES Cost comparisons

Project	Testing cost (member)	Analysis cost (member)	Totle drilling cost (member)	Time cost (hour)
					From the probe in detecting of embodiment 3	5000~6000	2000~3000	7000~11000	72~96
WES is detected	13000~15000	5000~7000	18000~22000	168~240

As can be seen from the above table, the probe synthesized using the present invention carries out capturing human genome target area, and then detects Human genome mutational load number, compared with detecting human genome mutational load using WES, testing cost and analysis cost significantly drop It is low, and time cost is relatively low, and therefore, the present invention is designed synthetic capture probe mixture for key area, can Effectively capture human genome target area.

It is described above, only it is the preferred embodiment that the present invention is implemented, any formal limitation not is done to the present invention, it is all Modifications, equivalent substitutions and improvements done within the spirit and principles in the present invention etc., it is required to the protection included in the present invention Within the scope of.

Sequence table

<110>Shanghai thinking enlightening biomedicine Science and Technology Ltd.

<120>Human genome mutational load capture probe and application are detected based on high-flux sequence

<130> OICN170053

<160> 825

<170> SIPOSequenceListing 1.0

<210> 1

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 1

ccgagctgcc ggtctgagcc tgaggcatgg agcctcctgg agactggggg cctcctccct 60

ggagatccac ccccaaaacc gacgtcttga ggctggtgag cccccgagcc tcctctccgt 120

<210> 2

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 2

ccttaggtgc tgtatctcac cttcctggga gccccctgct acgccccagc tctgccgtcc 60

tgcaaggagg acgagtaccc agtgggctcc gagtgctgcc ccaagtgcag tccaggtagg 120

<210> 3

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 3

tgggctcccg aaggggcctc ccgcagactt gcgaagttcc cactctctgg gcggcaggtt 60

atcgtgtgaa ggaggcctgc ggggagctga cgggcacagt gtgtgaaccc tgccctccag 120

<210> 4

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 4

cccattttag tgtcacatat ttatccagat tacagcagca ttacatcctc tacttacttt 60

ttaaactcac tgcgactgct ccagtaggtc ttcctcatat tccccatggc tcggccatta 120

<210> 5

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 5

aaaaagtggc cattattgaa cttacagatg ggtggtatgc tgttaaggcc cagttagatc 60

ctcccctctt agctgtctta aagaatggca gactgacagt tggtcagaag ccaaggtcta 120

<210> 6

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 6

ctccgtgaga gctggaaaac caaagtgaac tggctggccc acaacgtgtc caaagacaac 60

aggcagtagt ggctcctccc agccctgggc ccaagaggag gcggctgcgg gtcgtgggga 120

<210> 7

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 7

aaaaatgact gtaacaaaag tgcttctggt tatttaacag atgaaaatga agtggggttt 60

aggggctttt attctgctca tggcacaaaa ctgaatgttt ctactgaagc ccaagaggag 120

<210> 8

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 8

catcccacaa tgactggccc cagatcccag aagcacctct cggagttcca tggtgacata 60

gtgctggagc tccttggcgg ctttggccct ggtttcctca ttccggctct ttaggccact 120

<210> 9

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 9

agtattccaa ggccttgctt aggatcacta ctttgggggc cttggagcag ctggccaggg 60

tgggcacctg gtccctcagc gccaagaatc gcgaacgcag gtcattccgc ctcttgcgct 120

<210> 10

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 10

aaatctgcaa gtctgaaaaa tgtggatgct gctgtcagtc ccaggggggc tgcagcacag 60

gcaggggaga gggaatctgg ggtggtggca gtctcccctg agaaaagtga gagtccccaa 120

<210> 11

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 11

cgccctttcc tggcggctgg gtctttaaca ccgcccagcg cacatgtcgg gggaggcctg 60

gcagctgcag ctgggagcgc acagacggct gccccgcctg agcgaggcgg gcgccgccgc 120

<210> 12

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 12

cctgacctcc ttgccagcat ctccaacatc tctccccacc tcatgattgt cattgcctcc 60

gtgtgagcca ctgagtggtt atcacctcag tgaatcttcc cagggctctg cagtaaaaac 120

<210> 13

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 13

aaaatgtttt taaagaagcc agctcaagca atattaatga agtaggttcc agtactaatg 60

aagtgggctc cagtattaat gaaataggtt ccagtgatga aaacattcaa tgcactaaca 120

<210> 14

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 14

aaacacaaca aaaccatatt taccatcacg tgcactaaca agacagcaag ttcgtgcttt 60

gcaagatggt gcagagcttt atgaagcagt gaagaatgca gcagacccag cttaccttga 120

<210> 15

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 15

agtgtgggca ggccccaagc ctcacatttg gagatgacgc cctctaggcg gatgatgttg 60

tggtggctga actggcccat gatgccggcc tcgccgagga agtccactcg ctgcttctct 120

<210> 16

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 16

aaacctttca ttgtaatttt tcagttttga taagtgcttg ttagtttatg gaatctccat 60

atgttgaatt tttgttttgt tttctgtagg tttcagatga aattttattt cagatttacc 120

<210> 17

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 17

aaactagttt cactcacctt ccttgccctg cgccgccgcg gccgcggcca gcgcacagcc 60

ccacagcagg gcgaagcagg cgcgggctgc ctggagctcc atgccgcgct tatgattaaa 120

<210> 18

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 18

aaactgtaag tgaaaaaaat aataaatgcc aactgatatt acaaaataat attgaaatga 60

ctactggcac ttttgttgaa gaaattactg aaaattacaa gagaaatact gaaaatgaag 120

<210> 19

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 19

cctctctgag gctccaggac tcacctgcag gcaggctccg ccaagggttg tggccggcaa 60

ccggcgcctc aaggagaggg cgaccaccgc cgccatcttg gctcctgacg ccctccctcc 120

<210> 20

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 20

ctccctccct ccctccctcc tcctttctcc ggcagcagaa agcggagagt cacagcgggg 60

ccaggccctg gggagcggag cctccaccgc ccccctcatt cccaggcaag ggcttggggg 120

<210> 21

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 21

aaataaatta ttgagcctca tttattttct ttttctcccc ccctaccctg ctagtctgga 60

gttgatcaag gaacctgtct ccacaaagtg tgaccacata ttttgcaagt aagtttgaat 120

<210> 22

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 22

tatgaaatct ttatactata tgttccacgt gttaagaata aatgtacatt aaatcttggt 60

aagacttttg tgaagctttt tattgttttc aaactaaaac ttgacctttt gtcggggggc 120

<210> 23

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 23

gggtcaggcc catagtggtc tgctgccccg tagcttctga agtccccttc caggccagca 60

tcctccttgg ccgtggccac cggctccaat ttcttgcaga acacacagcc cattccaggt 120

<210> 24

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 24

gaatggggat cccaggatct cacaatctca ggtacttttg gaactttcca gggcaaggcc 60

ccattatatc tgatgttggg ggagcagatc ttgggggagc cccttcagcc ccctcttcca 120

<210> 25

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 25

ggaaggagcg cccagaggac cggcccacct ttgactacct gcgcagtgtg ctggaggact 60

tcttcacggc cacagagggc cagtaccagc ctcagccttg agaggccttg agaggccctg 120

<210> 26

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 26

aaatatttct ttttaggaga accctcaatc aaaagaaact tattaaatga atttgacagg 60

ataatagaaa atcaagaaaa atccttaaag gcttcaaaaa gcactccaga tggtaaaatt 120

<210> 27

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 27

aggaaaaaag gaaaaacaaa accccaaatg ccaaaggaat ttcagtggga tgaagttcct 60

ccaccactta gagagtatct agggaaaaag agagagagag aagtcaacac atgtcatttc 120

<210> 28

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 28

gctttttggt cagttagtag ccagtgaggt atgcaattct tttctgcaac tgctgctgcc 60

ggcatcggag ctgtcttttc tctgtagcca tcctcttctc agcccccacc agggcttgca 120

<210> 29

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 29

gggacccgcg cccgtgccct ggccacccgc agcctcacct cgctccagcc gcccgccacc 60

tggagcggac cggctccccg ccggctcggg gcagcccggc agccagcaca cacgcacatg 120

<210> 30

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 30

aaatttttta ggatctgatt cttctgaaga taccgttaat aaggcaactt attgcaggtg 60

agtcaaagag aacctttgtc tatgaagctg gtattttcct atttagttaa tattaaggat 120

<210> 31

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 31

cactaaagct tgctctgccc ccaggcctat gtgaacatgt cgctgtttga gaacttcact 60

tacgcgggca ttgatgccac agctgaggag gcctgagctg ccatccagcc agaacgtggc 120

<210> 32

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 32

actcctcttg accaagaagt gactcacccc aaaagtgtct tcttctggtt tgtgggtcac 60

agtgatagga ggtgtgggac tcacttcgtc aactgaaaac caaacacaaa aaggaggagg 120

<210> 33

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 33

ctcagagagg actcctttgc ccctgtgttc ctcccaggcc cagatggact accgaagatt 60

gcagccttct tgcctgggga ccatgcccct gtctgtgtgc ccacccatgg ctgagtcagg 120

<210> 34

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 34

gatgattatg atacggattt tgttccacct tctccagaag aaattatttc tgcttcttct 60

tcctcttcaa aatgccttag gtaaactagc taaataatta gcattattat ttgtttctgg 120

<210> 35

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 35

tcactggtgt ctgtctttcc aagaccagcc catatacttg atgtgtcagc ttgatgtgag 60

agaatgtgtg gacaacctgg aggaagggtc aaggggtcca aataggcctg tggatatagc 120

<210> 36

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 36

atcagctaga aggtctaaac tggctagctc attcctggtg caagtaggta gaaaaatatg 60

agtgcaattt tccttactgt ttctggcttc tttattgtta gatgtcaaga attttttttt 120

<210> 37

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 37

aggggaaaaa gaaaaacgac taattcatct tttcctgatc gtcaggaccc taaagaatgg 60

ccgagccttg ggggaacgag ttggcgtccg cagctgccag gggggaccta gagcaactta 120

<210> 38

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 38

gacggtctct cttcaaaatg tttgcaactg ctgcgttagc atgagttggc acccactgtt 60

aacgtggttc atgactttct gtttaagctg tgccacctgt tccctgagca tgttggccgt 120

<210> 39

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 39

tattcatgct tcttatttta aaagtgcttc aaatccttca ataaggttct gaaagcttgt 60

ccgattggat ggttggaatt cccagcattt cctcataagt tgataaacct gtaaaaagaa 120

<210> 40

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 40

tgttttggtg gtgtcgggtg ggggttagta gggaagcgcg gggatgcggg gagcgagaac 60

tccccccggt gtctacggcc ggaggaggtg ggggttttat tcttctgaaa aagttgaaag 120

<210> 41

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 41

aaaagtactt aaaagccaca tttctctcct ccttgcagac ctgaaaggaa gcggagagat 60

gtcatgcaag tggccaacac caccatgtcc agccgaagca ggaacaccac ggccgcagac 120

<210> 42

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 42

aatatgcaaa tctacatacc tgcatttatt cagctgtcca gtgttctcca agaagcaaac 60

tggattttct tctctacttt ccaaagctac ttcagagaag cgctaaagac aaaaataaat 120

<210> 43

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 43

aacacaatca aggatgatac acagcacagt cctcctcacc cctacagagc tagttctata 60

ctggctggat caaacctgca cttcaacaga caatggcaag acagactgta tttgcatgta 120

<210> 44

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 44

ggatgaagag gtgggagggc tgcacggagg tccggagctg agggccggcc caggggtgct 60

caagggacaa gggtctggag ttctcatggg gctgtggctt cctcgtcccc gaagaccttg 120

<210> 45

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 45

gccaccaccg ccaccagctg agccagaaga ggggggaggc actgttgaat agtctgccat 60

ggttgcacta taagagccgc tgccgcctgt tcagagactt cctctcagct aacagctaag 120

<210> 46

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 46

cttcagtgaa tataagaatt atgactaagc caagaacttc cagtttttat tttttaaaca 60

tcatttaaca agaaaaaaca ttcaaccaaa ttaaaaagaa ctaggttgga ttaatttaca 120

<210> 47

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 47

ctacgtaatc agtcggcgcc ccaggcgcct gagtccccgc cccggccacg tgggcctccg 60

aaccacgagt catgcggcag gccgcaccca gacccgcccc tcccacacgg gacgtttcaa 120

<210> 48

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 48

aagaagagca aaatgttctt caaagatatt gaagaacaat atcctactag tttagcttgt 60

gttgaaattg taaatacctt ggcattagat aatcaaaaga aactgagcaa gcctcagtgc 120

<210> 49

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 49

cagcatcttc tgtttcctgg tgagtgattc ctgctacttt ggatggccat gacgggctgg 60

agctgccttg tgacaggagc aggagggttt ctgggacaga ggatcatccg cctcttggtg 120

<210> 50

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 50

aagaatgagt ctaatatcaa gcctgtacag acagttaata tcactgcagg ctttcctgtg 60

gttggtcaga aagataagcc agttgataat gccaaatgta gtatcaaagg aggctctagt 120

<210> 51

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 51

gtctctacac tggaggtgga ctctctcacg cataaacctg catgttgttg tgtggtggct 60

cagacatgtg tgtcccaggt ccccgctgac ctcctccagc acccccaggg gtagggctgg 120

<210> 52

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 52

cccgatagag gagccccact ctctcctccc ctcctcctgc ttcaaaggct caggccctgg 60

cgctacgctc cgaagcccag gcgcaaatgc ctcgactccc cgcgccccga gtccgccgct 120

<210> 53

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 53

aagcaaatgc ttttgaagca ccacttacat ttgcaaatgc tgattcaggt acctctgtct 60

tttttttttt gtaaatagta catatagttt tatagatgac gattccttct gtgttttttt 120

<210> 54

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 54

gtcttaggac tgcgttttca cctcctgcgc cgtggtgagc tgcgtcctct ctctgcagac 60

caagctgtac accctgcctg caagccacgc cacgcgtgtg tatgagatgc tggtcagcca 120

<210> 55

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 55

gccggggctt ccatctcctc aagcggcgcc gcgcggcggg tgggcgcgaa gaaaagcagc 60

ctcgcggggg tcgcggtgac gtcggggacc tcggcgccaa tgggcggcgg ccgcgcgacc 120

<210> 56

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 56

gcctgagctt ccagagggcc taggagcagt aagggagtga gtgggcaact cggcgcatga 60

aggaggtact cctcattttc gttctctctc tctgtgcccc agcccgttgg cagacccgga 120

<210> 57

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 57

aagtaaaaat gatactgttt gtattcataa agatgaaacg gacttgctat ttactgatca 60

gcacaacata tgtcttaaat tatctggcca gtttatgaag gagggaaaca ctcagatttg 120

<210> 58

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 58

cccccagtaa atttcccacg acactaagat tttctacgat ccacgaggag ctgcttatta 60

gttgccaaag taggaattgg tgaagccaac gtagtcatag ccagagagat ggcttcgacc 120

<210> 59

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 59

cctaataata ttaatgacaa attgcatgga agagaaatat gtacttacgg tttcctttgg 60

aaattgctcc atttttccta aaggtttaga acctggcaag ataaaatgtg tcagagagag 120

<210> 60

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 60

tcgggtggcg gggccgcctg gcgtcacttc cgtccagacc ggaacccaag atggctgcgc 60

tgttgctgag gtgacttcag tgggactggg agttggtgcc tgcggccctc cggagatctg 120

<210> 61

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 61

tgggatccct ggcgctttcc caggaatcct cagaatgtga ggtttctctc aaaggcatct 60

tgcatcagcc tgtggatgta tgcctaccac cgggctcctt caccagcaaa gtggaaaaag 120

<210> 62

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 62

aataatatcc ttaatgatca gggcatttct ataaaaaata aactattttc tttcctccca 60

gggtcgtcag acaccaaaac atatttctga aagtctagga gctgaggtgg atcctgcttg 120

<210> 63

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 63

tccctttctg tataaacagt gccagttctg ggctttgtaa cctttgctct ttatagtctt 60

tcattcctgg ggaagtgatg gggcatgggc ccagagctgg ggtgtatgtg gtatggacac 120

<210> 64

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 64

actcaagtat gagtctttca ttttctgaaa acaagaacac aggaaaacaa gtccttttcc 60

ctctcccctc agaaatgtgt gcattttccc accaggctaa cagtggctac ctctgcacca 120

<210> 65

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 65

aatatcgtag gtaaaaatgc ctattggatc caaagagagg ccaacatttt ttgaaatttt 60

taagacacgc tgcaacaaag caggtattga caaattttat ataactttat aaattacacc 120

<210> 66

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 66

actgctgccc cggatcccgc ggggctgagg ctgctggagc cccggagctt ccccgacgcg 60

gcccacctgc tgccccatcc ctgctctcgc gtactcccgc gcccccgccg acccctggtg 120

<210> 67

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 67

cgctgctgct gctgcatggc cggtgggtag cctccgggtc cttgaggctg ctggaactgg 60

ccgtgccccg ccatgccccc agccatgccg gcactccctt gctgctgctg ctgttgctgc 120

<210> 68

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 68

aatgagattc atcagtttaa caaaaacaac tccaatcaag cagtagctgt aactttcaca 60

aagtgtgaag aagaaccttt aggtattgta tgacaatttg tgtgatgaat ttttgcctgc 120

<210> 69

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 69

ccttagcttg ttcttttgta attgaagggc attgttctgt gcccagtcct gctggtagac 60

ctgctccccg gtggctgggt tacctgtctc ctgaagcatc tggtcttcat cgatgtcata 120

<210> 70

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 70

gccccgagcc ggcggaggcg agggggggga agatggcgga cgtgcttagc gtcctgcgac 60

agtacaacat ccagaagaag gagattgtgg tgaagggaga cgaagtgatc ttcggggagt 120

<210> 71

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 71

atgctgggtg gtggctctgc tgggctcaca aggtgccatg acttcgagat cccagggcga 60

accagccggt cttctcctga gccaggtcca gctctcgcag gcggatgttc acctcaccga 120

<210> 72

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 72

aattattgag cctcatttat tttctttttc tcccccccta ccctgctagt ctggagttga 60

tcaaggaacc tgtctccaca aagtgtgacc acatattttg caagtaagtt tgaatgtgtt 120

<210> 73

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 73

catcatactc catctgcagg gcttcggcca tcgctagctc tttgcggctg atgcccactg 60

actccaggga cttccagtgt tccccattgc cctgagtcga agacatggtg aggatggggg 120

<210> 74

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 74

aatttaattt caggagccta caagaaagta cgagatttag tcaacttgtt gaagagctat 60

tgaaaatcat ttgtgctttt cagcttgaca caggtttgga gtgtaagtgt tgaatatccg 120

<210> 75

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 75

attatgatgg tacagatgaa attaaacgga agtatgctgg cctgtttaaa aattactgta 60

acattagtgc ttcagaatat ttaacagatg attatgaagt gtgtaatagg ggcaaatatt 120

<210> 76

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 76

aatatgctta taaaggaata aggggtttaa ggaaatgtct tcttctgggg tacaaacaag 60

tttggggcat tacaggacgt aatcggatac ggcagtatgg ttaaggtgtc tgaaaagtct 120

<210> 77

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 77

actgccaaca gttggtatta ggaacctgcg tgtcacttgt tgagaacatt catgttttgg 60

gtgcagaaca ggcttcacct tgcaacgtaa tgctggtgct tggttgcact gtgccgcaga 120

<210> 78

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 78

actgcatctc caaggaagtt gtaccgtctt tggcctgtga atggtctcaa ctaacccttt 60

caggtcttgc tggagcccag atggagtgca tacccctatt gcatatttct tcatgtgacc 120

<210> 79

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 79

actgcagtgc ttctggttat ttaacagatg tgcatgaagt ggggtttagg ggcttttatt 60

ctgctcatgg cactgcactg aatgtttcta ctgaagctct gctgcaagct gtgtgcctgt 120

<210> 80

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 80

acaattatga atctgatgtt gaattaacca tgcatattcc catggtgcag aatcaagatg 60

tatgtgcttt tgctgtgcat tattgcaacg ttgagctgtt gccacctgaa tgctacatga 120

<210> 81

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 81

tctgtcccaa ctaaaatgga gcttataaac ttacttagca aggaacctca aggagggctc 60

gttcttaacc atttgcaaga tgcctctgaa aagagcggcc ctccgcattt gtgcctcagc 120

<210> 82

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 82

acaccgcaga ctgatgtgct ttgttctgga tttcgcaggt cctcaagggc agaagagtca 60

cttatgatgg aagggtagct gttagaaggc tggctcccat gctgttctaa cacagcttct 120

<210> 83

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 83

acactcttgt gctgacttac cagatgggac actctaagat tttctgcata gcattaatga 60

cattttgtac ttcttcaacg cgaagagcag attgctccat ttctttctgt tccaatgaac 120

<210> 84

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 84

acagtactat agctgtgcat gactgcaatc atctctccga tgcacaagat acttatttaa 60

gtaacagtag catgtctaac agctattcct accattctga tgaggtatat aatgattcag 120

<210> 85

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 85

cagtttttcc ttttgcctca tcttagatca cagcaaagat actcatttgt tggtagtgcc 60

aggaagcagg cagtttccat ggtaactgac agaccgagtt tactgtggaa atttccggaa 120

<210> 86

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 86

acatgagtag tctcttcagt aattagatta gtttgcgtga tgtggtgttt tctggctgcc 60

ttgtacacga gcatctgtgc tttgctctgc tattccatta tcatgagtta cctctagcac 120

<210> 87

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 87

accacattgg tgcgtcaatg cctgctgtcc tagaagatga agtatatgaa acagttgtag 60

atacctctga agaagatagt ttttcattat ggcagactaa atgtagaaca tgcaatctac 120

<210> 88

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 88

accagaactt tgtaattcaa cattcatcgt tgtgttgctt tgccttctcc cattcctttc 60

agagggaacc ccttacctgg aatctggaat cagcctcttc tctgatgacc ctgaatctga 120

<210> 89

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 89

acccatgcct gagagtgcgg tccttgcccg aaggcagatt ttcgccaagc tgcttcgagc 60

cccgcccctt ccctgggtct ccatttcccg cctccggccc ggcctttggg ctccgccttc 120

<210> 90

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 90

ctaactttct ttctgtcctg aagctcacca tcactttcag aatcactctc tatttcctgc 60

ctcctttttt taagaggccc tctatctttg atatcatttt tttctaagtt ttttgaaaaa 120

<210> 91

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 91

accttgcata tgcgtttgca tagcagatgc aagagagtgc catcaatcct taatattaac 60

ttgctaggaa aataccagct tcatagacaa aggttctctt tgactcacct gcaataagtc 120

<210> 92

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 92

acctgtgggc atgttggtga agggcccata gcaacagatt tctagccccc tgaagatctg 60

gaagaagaga ggaagagaga gggacagggg aatggagaga aggtgcatct agttattgca 120

<210> 93

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 93

acctagtcat gatttctaga ggctgcgaat catactgcat gtcagacaag ctctgcggta 60

acaattatga atctgatgtt gaattaacca tgcatattcc catggtgcag aatcaagatg 120

<210> 94

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 94

accttgtgat gttagtttgg tgccttcaga tatatgttgc tgtagtatag ggaagcttca 60

taagtcagtc tcatctgcaa atacttgtgg gagcagaagc acagcaagtg gtgcatctgt 120

<210> 95

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 95

acgtgcctgg actcattact cctgcttgcc atggactttt actgcaccca tatcgtatac 60

caccactttt tcccatcaag tcatttgtta tgccttgctg taagtgcaat ctgctagaca 120

<210> 96

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 96

acgagatact ttcctgagtg ccataatcag taccaggtac caatgtgcta ctgctactct 60

ctacagatct ttcagtttgc tgcacccttt ctccacttaa catgagatct ttggggtctt 120

<210> 97

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 97

acgtatttct agcctaccaa aatcagagaa gccatttgct gaggtgccag tggttgctaa 60

gagagatgaa gagcagcatc ttgaatctca tacagactgc attcttgcag aatgggatcc 120

<210> 98

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 98

actaaggaac gtcaagagat acagaatcca aattttaccg cacctggtca agaatttctg 60

tcttgctctc atttgtatga acatctgact ttggtgcaat cttcaagcaa tttagcagtt 120

<210> 99

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 99

ccagaagctc tagggcctcc cgggggggca gtttaggcca aatctgaagc agcgcctgaa 60

gctgtttaaa aaatgaaact ggttcagaaa taatggggga caaaagtaat ctaattttcc 120

<210> 100

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 100

actacaggca gaccaaccaa agtctttgtt ccacctttta tgccttgctc acattttcac 60

agagttgaac agtgtgttag gaatattaac ttggaggtgc acagactgca gctgcacatt 120

<210> 101

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 101

actactttga aacagaagca gtagtgcttg cttgcgcttt tatggaagat gatgaactga 60

cagattctaa actgccaagt catgccacac attctctttt tacatgtccc gtgcatgagg 120

<210> 102

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 102

actcagcatc tgcagaatga tgcacactca aaggattaga agttgtgcac tgcatcagga 60

agtgctgtcc taagaagcta aagagcctca ggcagataca ctcccaagat caatctggat 120

<210> 103

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 103

actcattaac tttctgaatg ctgctattta gtgttatcca aggaacatct tcagtatctc 60

taggattctc tgagcatggc agtttctgct tattccattc ttttctctca cacaggggat 120

<210> 104

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 104

ttttgtttct cccacacaga cactattgtg taactatccc cgaaattcta cccaaattgc 60

ttctgtctgt taaatggaat tctagagatg aagtagccca ggtaaatgta tgtttgagat 120

<210> 105

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 105

actgactcac acatttattt ggttctgttt ttgccttccc tagagtgcta acttccagta 60

acgagatact ttcctgagtg ccataatcag taccaggtac caatgtgcta ctgctactct 120

<210> 106

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 106

actgttcagc ccagtttgaa gctgctgctt ttgaagcacc acttacattt gctgctgctg 60

attcaggtac ctctgtcttt gcagatttgt tgctagtaca tatagtttta tagatgacga 120

<210> 107

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 107

cctactcgca gcagggcacc cctggcatgg ctcttggctc catgggttcg gtggtcaagt 60

ccgaggccag ctccagcccc cctgtggtta cctcttcctc ccactccagg gcgccctgcc 120

<210> 108

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 108

acttttattg atttagcaga tggggggtgc gcagatagga tctgattctt ctgaagatac 60

cgttaataag gcaacttatt gcaggtgagt ctgcgagaac ctttgtctat gaagctggta 120

<210> 109

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 109

agtgcgaata aatactgcag attatgtagg tgcttatttg tatgtgcata attctgccag 60

tactatagct gtgcatgaca tgcatcatct ctccgtgcaa caagatactt atttaagtaa 120

<210> 110

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 110

agtgcgtaat tgtgctgcct tcctgagttt tcatggacag cacttgagtg tcattcttgg 60

gatattcaac acttacactc ctgccctgtg tcaagctgaa aagcactgct gattttcaat 120

<210> 111

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 111

agtgctctgt attaacagtc tgaactactt cttcatattc ttgcgcagat atttcaggat 60

gcttacaatt acttccagga agactttgtt tatagacctc aggttgctgc acccctaatc 120

<210> 112

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 112

ttaaacaagt tttaccaact actgaaggtt cagtgggctg atagcctttc atggggcgct 60

gaatgcctta cggcacaact tcttcaagaa acctttcaat ggtctttgaa gaagtgtaaa 120

<210> 113

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 113

agaagcagtt cctttaacta tacttggtgc tttgttgcat gtgctcccca tgcgcattgc 60

catttagctc acttctataa atagactggg gctgccacaa tgccctggtt ccaataccta 120

<210> 114

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 114

agaaggatca gattcagggt catcagagaa gaggctgatt ccagattcca ggtaaggggt 60

tccctctgaa aggaatggga gaagtttaat ttacacaacg atgaatgttg aattactgcg 120

<210> 115

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 115

agaatagcct ctagaacatt tcagcaatct gaggaacccc catcgtggga tcttgcttat 60

aatactccac tatgtaagac tgcggctggt gctggaactc tggggttctc ccaggctctt 120

<210> 116

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 116

agaattcagc cttttctaca ttcattctgt ctttagtgag taattgcctg ctgttctcat 60

gctgtaatga gctggcatga gtatttgtgc cacatggctc cacatgcaag tttgtgccag 120

<210> 117

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 117

acattttttc agctggtctt tcaggataag tggcacatgt ctgaacatgt caaattacat 60

gtcttttccc ctctccttgt ggggaggaaa tcactggtat aaatcatggc tttcaaacac 120

<210> 118

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 118

tcatttaccc cctcccggtg ctctgggggg cagcgcctct cagacattcc cctcaaactg 60

cttcccgccc cctcctccca actgcggagc tccgccaagc gtctcttctc gcgagcctcc 120

<210> 119

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 119

agaccattga gatcacagct gcccctgcgt gttgcgtgct gcagaattct ctcaataatg 60

attgcaacct tgtttctatt gagactgtgg tgccacctaa gctcttaagt gataatttat 120

<210> 120

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 120

agacttttga gtgcttgcac tgatattatt tgcctttgca acatatatga aatatttctt 60

tttaggagaa ccctcaatca tgcgtgcctt atttgctgaa tttgacagga taatagtgca 120

<210> 121

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 121

cgtctgagga gcccgtgtcc ccagggcccc tgtacgtgct ggtggagtac gcggccaagg 60

gtaacctgcg ggagtttctg cgggcgcggc ggcccccggg cctggactac tccttcgaca 120

<210> 122

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 122

agagcagcat cttgaatctc atacagactg cattcttgca gttgcgcagg caatatctgg 60

aacttctcca gtggcttctt catttcaggg tatctgcaag tctatattca gaataagagc 120

<210> 123

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 123

agagttctca cagttccaag gttagagagt tggacactga gactggtttc ctgcttgcca 60

gtatggttgc gaacagtcaa gcaattgttg gccagttctg tgcttttcct cctgaagaga 120

<210> 124

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 124

agagttgaac agtgtgttag gaatattaac ttggaggtgc acagactgca gctgcacatt 60

gatggacatg gctctgatga tagttgcaat aagattaatg acaatgagat tcatcagttt 120

<210> 125

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 125

cagtgctctt gctcgggcag cacagtggac tgtcacgggc tggcgctgcg cagcgtgccc 60

aggaatatcc cccgcaacac cgagagactg tgagtatgcg ctcttcgtct tcccctctcc 120

<210> 126

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 126

aatttttctt tttctttctt ttagttctct acatggaaat gacatttctg ttgtgcctga 60

aggtgctttc aatgatcttt ctgcattatc acatctgtga gtacctagtt tatgaatata 120

<210> 127

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 127

agatatgata cggtgcttga tagaagcaga agatcggcta ttgctgcgat aatggtgcgg 60

gatgacacag ctgctgcaac acttgttctc tgtgtttctg acataatttc attgagcgca 120

<210> 128

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 128

agatgagctc taattttgtt gtatttgtcc tgttttgcgc catctagtta caatagatgg 60

aacgcagatg ttctgattgc gcagaattcc aatatcttaa atggtcacag ggttatttca 120

<210> 129

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 129

agattgatga cctgcagaac tgctgcaaga gaagagcctt ggatttcttg agtagactgc 60

ctttacctcc acctgttagt cccatttgta catttgtttc tccggctgca cagaaggcat 120

<210> 130

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 130

agattttgtg ggttgttgcg gtccctgctg gtcttcagaa taatctaatt acagtactgt 60

atctacccac tctcttttca gtgcctgtta agttggctgc ctttgccatt acccgcagat 120

<210> 131

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 131

acttaggccc tttttctctc tagatgtaat aatgaaactt cctggactat tttggccaac 60

aatgtctcaa acatcatcac ggagatccac tcccgagaca ggagtaccgt ggagggccgt 120

<210> 132

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 132

agcacaacat atgtctttgc ttatctggcc agtttatgaa ggagggtgcc actcagatta 60

aagaagattt gtcagattta acgcagatgg aagttgcgaa agctcaagaa gcatgtcatg 120

<210> 133

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 133

agcatattgc aatgactcta ggtcaagatt ttgcatcgga catctccttg aatatagata 60

tgctaccaga tgctgctaat gattacatga actgctgggc aggactctta ggtccaattt 120

<210> 134

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 134

agcattctgc ctcatacagg caattcagta aacgttaagt gtgcttgcga gtgaatgtgc 60

tgctaatatc cttaatgatc agggcatttc tattgctgct tgcctatttt ctttcctccc 120

<210> 135

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 135

agccacggga gccccttcac ttcagctgct ttttagatcc agactttcag ccatcttgtt 60

ctgaggtgga cctaatagga tttgtcgttt ctgttgtgaa tgcaacaggt aatgcacaat 120

<210> 136

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 136

agccatttgc ttgtccatat ctaatagtaa taattttgag gtagggccac ctgcatttag 60

gatagccagt ggttgcatcg tttgtgtttc acatgtgcca atttgctgcg tgtgcgacac 120

<210> 137

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 137

agcctcagtc aattaatact gtatctgcac atttacagag tagtgtagtt gtttctgatt 60

gttgcaatag tcatataacc cctcagatgt tattttccaa gcaggatttt aattctgccc 120

<210> 138

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 138

agctcttcaa caagttgact tgctctcgta ctttcttgta ggctcctgaa atttgcttgt 60

ttgagtgcca cactcagcaa gtgattatca accttttaag gacacttgca taagtgcaga 120

<210> 139

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 139

cactctttac aagttaaaat gaatttaaat ggttttcttt tctcctccaa cctaatagtg 60

tattcacaga gacttggcag ccagaaatat cctccttact catggtcgga tcacaaagat 120

<210> 140

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 140

aggtgccaga catagtttgc cactgcatac tgtgcgtgcg tgtcccagtt ggtactggaa 60

atcaactagt gaccttccag ggacaacccg aacgtgatga tgcgatctgc gaacctactc 120

<210> 141

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 141

aggtgccagt ggttgctaag agagatgaag agcagcatct tgaatctcat acagactgca 60

ttcttgcagt tgcgcaggca atatctggaa cttctccagt ggcttcttca tttcagggta 120

<210> 142

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 142

ggagtgaaag tgggagggaa cactaaccat attaggcttg gatgggcaac agcgcacagg 60

gaagaagccc tcccacagcc acattcgcag caactgaaaa gcaaacaaga gagcccaaga 120

<210> 143

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 143

aggaatttga tttaatcaga actgagcata gtcttcacta ttcacctacg tctagactgc 60

atgtatctgc aatacttcct cgtgttgata agagtgcccc agagcactgt gttgcctcag 120

<210> 144

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 144

cgcctattta gctctttgta tattatctcc tggagagaca gctaggcagc aaaaaaacaa 60

tctattaaaa tgagaaaata acgaccatag gcagtctaat gtacgaactt taaatatttt 120

<210> 145

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 145

aggatattct tcataactct ctagataatg atgaatgtag cacgcattca cataaggttt 60

ttgctgacat tcagagtgaa gtgcttttac aacataacca tgctatgtct ggattggaga 120

<210> 146

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 146

aggattcaga gttgcatcaa agtgtttgtt ccaatacagc agatgtgcta ttacctagat 60

cttgccttgg caagtaagat gtttccgtca aatcgtgtgg cccagactct tccagctgtt 120

<210> 147

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 147

aggcatgagc cactgtgccc tgccactacc gcagaaactt agtgtgcaat atttagtgaa 60

tgtgattgat ggtactttaa ttttgtcact ttgtggcaga atgtttaggt ttattgcatt 120

<210> 148

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 148

aggccagtac ggaagaatgt gagtgcaata agcaggacac aattacaact tgctgctata 60

tctaagcatt tgctgcggcg acaattgctt attgacgctt aacctttcca gtttataaga 120

<210> 149

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 149

agggaagctc ttcatcctca ctagataagt tctcttctga ggactctaat ttcttggccc 60

ctcttcggta accctgagcc tgctgtgtat gggtgtgcgg gctaggactc ctgctaagct 120

<210> 150

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 150

agggagactg tgtgtaatat ttgcgtgctt tgctattttc aatgtgcagt tactttgatt 60

taggcagata tgttactaca taattatgat aggctacgtt ttcagcagat tatcagatgt 120

<210> 151

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 151

agggtcgtca gacacctgca catatttctg tgcgtctagg agctgaggtg gatcctgata 60

tgtcttggtc aagttcttta gctacaccac ccacccttag ttctactgtg ctcataggta 120

<210> 152

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 152

agggtgaatg atgtgcgctc cttcaccaca gaagcaccac acagctgtac catccattcc 60

agttgatcta tgctggacat ttagatgtaa aatcactgca gtaatctgca tacttaaccc 120

<210> 153

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 153

aggttttccc tgctattttg tcttcaatat tactctctac tgatttggag tgaactcttt 60

cacttttaca tatttgcgcc tcatgaggat cactggccag taagtctatt ttctctgaag 120

<210> 154

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 154

agtagtatga gcagcagctg gactctgggc agattctgca actttcaatt ggggaacttt 60

caatgcagag gttgaagatg gtatgttgcc aacacgagct gactctgggg ctctgtcttc 120

<210> 155

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 155

agtagtggct gtgggggatc tggggtatca ggtaggtgtc cagctcctgg cactggtaga 60

gtgctacact gtccaacacc cactctcggg tcaccacagg tgcctcacac atctgcccaa 120

<210> 156

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 156

tcagctaacc cattatggca acaaagggcc ctggacccac cacaccaaat ggagctgact 60

cagtgaaaac tggaattaaa aggaaagtca agaagaatga actatgtcga tgcacagtat 120

<210> 157

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 157

agtcatttaa ttgcattgta aatttctttg atcagtgccc agaagaattg cataactttt 60

cctttgcttc tgaattacat tctgacataa gtgcgaacaa aatggacatt ctaagttatg 120

<210> 158

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 158

agtctgtttc cacacctgtc tcagcccaga tgacttctgc gtcttgttgc ggggagtgcg 60

agattgatga cctgcagaac tgctgcaaga gaagagcctt ggatttcttg agtagactgc 120

<210> 159

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 159

agttaagtgc atcagcaatt acaatagcct aatcttacta gacatgtctt ttcttcccta 60

gtatgtaagg tcaattctgt tcatttgcat aggagataat cataggaatc cctgcttaat 120

<210> 160

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 160

agttatatag tttcttatct tttgctctcc cttctttggg tgttttatgc ttggttcttt 60

agttttagtt gcttttgaat ttacagttta gtgaattaat aatccttttg ttttcttaga 120

<210> 161

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 161

agttcagcca tttcctgctg gagctttatc aggttatgtt gcatggtatc cctctgcttc 60

tgcaacgata aatggcacca agtgcatgaa atactttgag aagctttcca tttgctgtgc 120

<210> 162

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 162

agttgatcta tgctggacat ttagatgtaa aatcactgca gtaatctgca tacttaaccc 60

aggccctcta ccctacactc tccggatgaa ggcttatagc aagacctctc aatgggagag 120

<210> 163

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 163

agttgttgaa ttcagtatca tcctatgtgg gcagaatgat aatattctac ttttatttgt 60

tcagggctct gtgtgacact ccaggtgtgg atcctgcgct tatttctaga atttgggttt 120

<210> 164

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 164

agtttcacac tgaagattat tttggtaagg tgcgtttatg gactggtgca ggaatacagt 60

tggctgatgg tggatggctc ataccctcca atgatggtgc ggctggtgca gaagaatttt 120

<210> 165

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 165

agtttgaatc catgctttgc tcttcttgat tattttcttc caagcccgtt cctctttctt 60

catcatctga aaccaattcc ttgtcactca gaccaactcc ctggctttca gactgatgcc 120

<210> 166

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 166

agttttagtt gcttttgaat ttacagttta gtgaattaat aatccttttg ttttcttaga 60

tgccacaaca tgcccatatt taccatcacg tgcactaaca agacagcaag ttcgtgcttt 120

<210> 167

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 167

attgcaacct tgtttctatt gagactgtgg tgccacctaa gctcttaagt gataatttat 60

gtagactgcc tgtgcatctc tgcacatcaa tgcgtatctt tttgtgcgtt tgcgtacatg 120

<210> 168

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 168

tgagttatat attcaaataa cacccaatga agaatgtaat tgataatctt tacctcttta 60

gggagcaatg aaatgaagtc tcgttgaaac tggggttcta tcacttgcat catatgtttt 120

<210> 169

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 169

attgcagatc gaagattgtt tatgcatcat gtttctttag agccgattac ctgtgtaccc 60

tttcggtaag acatgtttaa agcagactaa attctaatac agtatgagaa aagtctcgtt 120

<210> 170

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 170

ataactgcta tactgctgcc agtagtgctt ctcataactt agaatttgat ggcagtgatt 60

caagttgcaa tgatactgtt tgtattcata aagatgtgcc ggacttgcta tttactgatc 120

<210> 171

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 171

ataatagcaa atgtgtattt acaagtgcga gcagatgagg ttgataattg tcatctctaa 60

tacttctgtt tgcaggtgct atgtgcagaa aatattagat aatgtctttg ataagtgtgt 120

<210> 172

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 172

ataatcacta tagatggatc atatggtgcc tggcagctat ggaatgtgcc tttcctaagg 60

aatttgctaa tagatgccta agcccagtgc gggtgcttct tcaacttgca tacaggcaag 120

<210> 173

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 173

ataatttaac acctagccaa aaggcagtgc ttacagaact ttctactata ttagaagaat 60

caggaagtca gtttgaattt actcagttta gtgcaccaag ctacatattg cagaagagta 120

<210> 174

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 174

atacctctga agaagatagt ttttcattat ggcagactaa atgtagaaca tgcaatctac 60

tgcaagtaag aactagcaag actaggtgca tgcttttcca tgaagctgcc gctgatgaat 120

<210> 175

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 175

atacgtatgg cgtttcttgc cattgcataa tgcttaacag ctgcaatgca gagtcttttc 60

agtttcacac tgaagattat tttggtaagg tgcgtttatg gactggtgca ggaatacagt 120

<210> 176

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 176

atactttaac aggatttgga tgcacatcag ggaattcatt ttgcgttgct agctgctgcg 60

accacattgg tgcgtcaatg cctgctgtcc tagaagatga agtatatgaa acagttgtag 120

<210> 177

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 177

atagacctta atgaggacat tattaagcct catatgttaa ttgctgcaag caacctccag 60

tggcgaccag aatcctgctc aggccttctt actttatttg ctggagattt ttctgtgttt 120

<210> 178

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 178

atagattaca gatacagaac ttgcattaac ctagacttgc aggtcttatc accacgtcat 60

agtgcgtaat tgtgctgcct tcctgagttt tcatggacag cacttgagtg tcattcttgg 120

<210> 179

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 179

ataggtactc tatgctgcaa gattgtgtgt taacttttat gtattccctc atccctcttt 60

cttctcttaa ctgtctctcg aacttgcaag ttggctagaa atctgctttt tatgcattta 120

<210> 180

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 180

atagttaatt gcagatattg attcttttaa tgcacattgt cgcagagcat ctcttatgat 60

tagttggagc taccagttgg ctgctttgct agctaactag tgatctgtgc gtaagcctct 120

<210> 181

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 181

atatatgttc tctaggcctt ttagtgcaca tggagttgtt cctttggcca tgtatatgcg 60

aatctgtaag tgcggtgtgc ttgtagacat caagggaacg ggtactgttc tgcaaggaat 120

<210> 182

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 182

atatcattct tacattgcgg acactgtgaa ggccctttct tctggttgag aagtttcagc 60

atgctgcatc tattgcttat tgcgtgcgaa agaacaattt aatttacttc cttttgtaga 120

<210> 183

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 183

ttttacctgt tatgaaatat gtaacttgtc tgttgatctc ttcagaatca gcatccgtgg 60

tacttaagat ggcaatcacc ccaccttggg ggtcatcctc actcacagtc cctttataga 120

<210> 184

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 184

atatggtaca cattgttatt tctaatatga gaactgcgtc ttagagactt tgaatttaac 60

agcagaaatg agttgcttgt ttttattttg agtagttgct tgactttatt ttttagtatc 120

<210> 185

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 185

tcttgctttc caggggagat ggatcctatc ttactaacca tcagcatttt gagttttttc 60

tctgtcgctc tgttggtcat cttggcctgt gtgttatgga aaaaaaggtg accttcttca 120

<210> 186

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 186

atctgctgca cactagtttt tcctgcgtaa tatccaatgt tgcagatgca aatgcatacc 60

cactgcctgt tgctgaagat atttgcgttg aggaacttgt gactagctct tcaccctgca 120

<210> 187

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 187

atcaactagt gaccttccag ggacaacccg aacgtgatga tgcgatctgc gaacctactc 60

tattgggttt tcatacagct agcgggtgca aagtttgcat tgctgcggaa tctttggaca 120

<210> 188

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 188

atcaatgggc tgcgacccta aagtacagag aggcctgtaa agaccttgaa ttagcatgtg 60

agaccattga gatcacagct gcccctgcgt gttgcgtgct gcagaattct ctcaataatg 120

<210> 189

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 189

atcagagaag ctgcatccac tactaatgcc cactgcgaga taatattgca gaggatctgt 60

atttattttg tgcctgccat tttgctgata atcacttctt ccattgcatc tttctcatct 120

<210> 190

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 190

taaagtagtg aattaattgg ttataaatat agttttactg gctatgttat actcacatca 60

gtagctgcag ttaaaatttt ggaaaggatg actctagcca atccatctct gctatagtcc 120

<210> 191

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 191

atctacccac tctcttttca gtgcctgtta agttggctgc ctttgccatt acccgcagat 60

gcagaatcca aactgatttc atccctggtt ccttgagggg tgatttgtaa caattcttga 120

<210> 192

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 192

atctggaatc agcctcttct ctgatgaccc tgaatctgat ccttctgaag acagagcccc 60

agagtcagct cgtgttggca acataccatc ttcaacctct gcattgtgcg ttccccaaat 120

<210> 193

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 193

atcttgggag tgttgctgcc tgaggctctt tagcttctta ggacagcact tcctgatttt 60

gttttcaact tctaatcctt tgagtgtttt tcattctgca gatgctgagt ttgtgtgtga 120

<210> 194

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 194

gtgctgtatt aaatcataag tgaaaggaga taagctgaaa ttaatatggt tcattcatgg 60

taatcacaca ggaagagaaa cttttactat tgctagaccc tacccctttg ttattgtttt 120

<210> 195

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 195

ggttactaca gtaccccatg tgttttcaaa actgttagaa atgctgagtg tttccagttc 60

cactcacttc accaggatgc gtcgccgttt gatggctatt gcagatgagg tggaaattgc 120

<210> 196

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 196

atgaactcat tgcaacttaa tgatcttgaa caatgtagtt tttgtacaga gaatagttgt 60

agttgttgaa ttcagtatca tcctatgtgg gcagaatgat aatattctac ttttatttgt 120

<210> 197

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 197

atgaagctat tatatttgca tattttgctg tgccattttc ctacatatat ttgttctata 60

aagatgaatc tgagcagaat gctaatattt tggctaagag cctggtagaa gatcttacat 120

<210> 198

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 198

atgacctaga aagattgctg gaaggagtgc accatcgcca ccaattgtga aaggactgct 60

catacttgct gggcagccaa agcattgctg tgccagctca tgtcagagag atcagtgctg 120

<210> 199

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 199

atgatactga tccattagat tctgctgtag ctgctcagaa gccctttgag agtggaagtg 60

actgcatctc caaggaagtt gtaccgtctt tggcctgtga atggtctcaa ctaacccttt 120

<210> 200

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 200

atgatcatga tgctgccagc actcttattt taactcctac ttccaaggat gttctgtcaa 60

acctagtcat gatttctaga ggctgcgaat catactgcat gtcagacaag ctctgcggta 120

<210> 201

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 201

atgctgcatc tattgcttat tgcgtgcgaa agaacaattt aatttacttc cttttgtaga 60

aagaatactc tgcaggctgc tagccatgaa aagataatct cacaactgcc cttaagagcc 120

<210> 202

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 202

ttatgagatt ttttttttaa aaggtcgtct acagctgcaa gcagatcgcc atcaagaaca 60

tatccgagct agagattcat taattcagtc tttggcaaca cagctagaat tggatggctt 120

<210> 203

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 203

atgcgccacc gtgcctcgcc tcatgtggtt ttatgcagca gatgcaaggt attctgttgc 60

ggttcttggt atacctgttt tcataacaac atgagtagtc tcttcagtaa ttagattagt 120

<210> 204

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 204

tctcttttcc ttttatccag gctggacgta aagaaagaag tgatgcactc aattctgcaa 60

tagataaaat gaccaagaag accagggact tgcgtagaca ggtaatctgg atgaaagtgc 120

<210> 205

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 205

atgctgatct tcatgtcata atgaatgccc catcgattgg tcaggtagac agcagcaagc 60

aatttgaagg tacagttgaa atttgccgga agtttgctgg cctgttgtgc aatgactgta 120

<210> 206

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 206

atggataagg ggggactact actatatgtg cattgagagt ttttatacta gtgattttaa 60

actataattt ttgcagaatg tgtgcagcta gcagaccaat catgatgtgc gtctgaagaa 120

<210> 207

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 207

atggatattc tcttagattt taactaatat gtaatattgc ataattgttt cctaggcaca 60

attgcagatc gaagattgtt tatgcatcat gtttctttag agccgattac ctgtgtaccc 120

<210> 208

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 208

atgtatctgc aatacttcct cgtgttgata agagtgcccc agagcactgt gttgcctcag 60

tgctggtgca aacctgcagt tgcgaattta aattatctgc taactttgct gttgaaggtg 120

<210> 209

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 209

atgttgaatt tttgttttgt tttctgtagg tttcagatga aattttattt cagatttacc 60

agccacggga gccccttcac ttcagctgct ttttagatcc agactttcag ccatcttgtt 120

<210> 210

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 210

atgttgcaca ttcctcttct gcatttcctg gatttgtgca cggagctgct gactggcgct 60

ttgtgccctt gaatgtattc tgctgctact gagcatcaag ttcactttct tccatttcta 120

<210> 211

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 211

attacgaacc tgccctattt tgcactccac tgcggtgccc atcttataat cagctggctt 60

caactccaat aatattctgc gagcaagggc tgactctgcc gctgtaccaa tctcctgtga 120

<210> 212

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 212

attaggaacc tgcgtgtcac ttgttgagaa cattcatgtt ttgggtgcag aacaggcttc 60

accttgcaac gttgcaatgg tgcttggtaa aactgtgcct ttttctgatg ttcctgttca 120

<210> 213

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 213

attatctcag actgtgccga cgttgtacta catctctgat ctgcgaacag gagagttccc 60

aggccagtac ggaagaatgt gagtgcaata agcaggacac aattacaact tgctgctata 120

<210> 214

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 214

attcagacca gctcacaaga gaagtgcata ctgctatacg tactccagaa catttaatat 60

ccctgcaagg cttttcatat aatgtggtaa attcatctgc tttctctgga tttagtacag 120

<210> 215

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 215

attcagactc cccatcatgt gagtcatcag aacctaacag ttcatcactt ctggtgcacc 60

actcattaac tttctgaatg ctgctattta gtgttatcca aggaacatct tcagtatctc 120

<210> 216

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 216

attcagagga tattcttcat aactctctag ataatgatga atgtagcacg cattcacata 60

agggcagagc tgacattcag agtgaagtgc ttttacaaca taacctgcat atgtctgaca 120

<210> 217

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 217

attcagtcat tgtgcattca gccttagctt tttacacaag ttgtagtaga tgcacttctg 60

tgagtcagac ttcattactt gaagctgcaa aatggcttag agaaggaata tttgatggtc 120

<210> 218

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 218

attctcctca gatgactcca ttttgctgct tcaatgtgct ttctcttttg gtgcgtaatt 60

caatagctga cgaagaactt gcattgataa atacccaagc tcttttgtct ggttcaacag 120

<210> 219

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 219

attctgatga ggtatataat gattcaggat atctctctgc tgcttgcctt gattctggta 60

ttgagccagt attgaagaat gttgaagatc tgctgcacac taggcagacc tgcgtaatat 120

<210> 220

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 220

attgaactta cagatgggtg gtatgctgtt aaggcccagt tagatcctcc cctcttagct 60

gtctttgcga atggcagact gacagttggt cagaagatta ttcttcatgg agcagaactg 120

<210> 221

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 221

acagggcaca aggaccctgg tttcccaggc cataccatgc acaatgacct cggtgctctc 60

ccgaaatcgc tggatgccgt tgttggcctt gcacacatac gagcccaggt cgtgctggct 120

<210> 222

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 222

atttattttg tgcctgccat tttgctgata atcacttctt ccattgcatc tttctcatct 60

ttctcctgcc agttatactg agtatttggc gtccatcatc agatttatat tctctgttaa 120

<210> 223

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 223

atttgtcaat cctagccttc caagagaaga tgcagaagag tgcctagtgc cagtttgcgt 60

gtctaataat gctgaagacc cctgcgatct catgttaagt ggagtgcggg ttttgctgcc 120

<210> 224

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 224

agcagaatct tacagtcaga aatgaagaag catctgtgcc tgtatttcct catgatacta 60

ctgctgtaag ttgctatgac attgattaga ctgttgtgct tgctaacaat tttggaatgc 120

<210> 225

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 225

ctcttccttg gtcccctctt ctccagactg cagtatgggg gtctgggcca gctggcagat 60

ggtgtggtgg ggctggatga ctttaggaag agtcaggagc tgcgggtctg gccaggctat 120

<210> 226

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 226

ctgcaacatc cactctgcct cgaatctctc tgtgcgcagc agtaggaggc caagttccct 60

ctgcgtgttc tcattgccag gtatgtgttt gtctacaata ctgatggctt ttatgacaga 120

<210> 227

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 227

ctgcaagcaa tgcagtttca gatattgcag aagaggtctt ggctgcagca tgtcacccag 60

tacaacattc tgcagtggaa tacagtgata ctgactttca atcccagtgc agtcttttat 120

<210> 228

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 228

ctctgagctg aggccccaca ccagagtagg gggcggcgcg gcacccgtgc cccggcatgg 60

cgacaccgga cgcggggctc cctggggctg agggcgtgga gccggcgccc tgggcgcagc 120

<210> 229

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 229

ctgcagtgtc catgatagac tagtacatct tgcagttggt taaccagaat atctttatgt 60

aggattcaga gttgcatcaa agtgtttgtt ccaatacagc agatgtgcta ttacctagat 120

<210> 230

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 230

ctgcccataa tttaacacct agcctgcagg cagtgcttac agaactttct actatattag 60

aagaatcagg aagtcagttt gaatttactc agtttagtgc accaagctac atattgcgca 120

<210> 231

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 231

ctgcctgtaa atgaagatat ttgcgttgag gaacttgtga ctagctcttc accctgctgc 60

aattgcaatg cagccattaa attgtccata tctaatagta ataattttga ggtagggccg 120

<210> 232

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 232

tgacggacag acagacagac accgccccca gccccagcta ccacctcctc cccggccggc 60

ggcggacagt ggacgcggcg gcgagccgcg ggcaggggcc ggagcccgcg cccggaggcg 120

<210> 233

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 233

ctgctcacag ttttggaggt agcttcagaa cagcttctgc taaggtgctc aagctctctg 60

aacataacat taagaagagc tgcatgttct tctgcgatat tgaagaacaa tatcctacta 120

<210> 234

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 234

caaggaatat tataagaagt atatatggag gccatcgtat attctgttgt atacctagta 60

aacatggtaa aatgtaatta aacttaatta gtgcatgtgg ttgttatgtg gctcctgtaa 120

<210> 235

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 235

caaggtattc tgttgcggtt cttggtatac ctgttttcat aacaacatga gtagtctctt 60

cagtaattag attagtttgc gtgatgtggt gttttctggc tgccttgtac acgagcatct 120

<210> 236

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 236

caagttgcaa tgatactgtt tgtattcata aagatgtgcc ggacttgcta tttactgatc 60

agcacaacat atgtctttgc ttatctggcc agtttatgaa ggagggtgcc actcagatta 120

<210> 237

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 237

caagtggtgc atctgtccag gtatcagatg cttcattaca tgccgcaaga caagtgtttt 60

ctgtgctaga agatagtacc aagcaagtct tttcctgcgt attgttttgc agtaacgaac 120

<210> 238

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 238

caagtggtgc gcaagtttcc attttagtgc gttccttaca ctgcgttaag ggagtgttag 60

aggaatttga tttaatcaga actgagcata gtcttcacta ttcacctacg tctagactgc 120

<210> 239

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 239

caatagctga cgaagaactt gcattgataa atacccaagc tcttttgtct ggttcaacag 60

gagtgcaaca atttatatct gtcagtgaat ccactaggac tgctcccacc agttcagaag 120

<210> 240

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 240

caatgcagag gttgaagatg gtatgttgcc aacacgagct gactctgggg ctctgtcttc 60

agaaggatca gattcagggt catcagagaa gaggctgatt ccagattcca ggtaaggggt 120

<210> 241

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 241

agaggggaag agagaaaact ttgtgtggaa ggataaggag tgtgtttata gtttcagtaa 60

gagtgtacgt tttaattttt cttcttcctc tgcctctttg ccaagtagcc tgagtgcatc 120

<210> 242

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 242

cactgcctgt tgctgaagat atttgcgttg aggaacttgt gactagctct tcaccctgca 60

tgcattgcaa tgcagccatt tgcttgtcca tatctaatag taataatttt gaggtagggc 120

<210> 243

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 243

cacacacgct ttttacctga gtggtttgca tgtcactctg agaggatagc cctgagcagt 60

cttcagagac gcttgtttca ctctcacacc cagatgctgc ttcaccttaa ataactgcaa 120

<210> 244

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 244

cactaaatga atgaatgtta tacaccaagt atctccttca ttttatgtca tggagttcta 60

gcttctgata tcacagaaat atgtgatttc taaaatgttt cagactattg tgataagtat 120

<210> 245

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 245

tcctcttcat gatgcttggc ttgacgtggg ctattgtgag ggacgcaggc tgctcatcgg 60

aggaagatgc ttccagattg gtctcctccc cgggaggagg gggaggaaca ggagtggaaa 120

<210> 246

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 246

caccatcttt cagtaatttg cctgcatgac gaacactgcg ggtgcgagga gaggcacctg 60

atatatgttc tctaggcctt ttagtgcaca tggagttgtt cctttggcca tgtatatgcg 120

<210> 247

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 247

cacctgcatt taggatagcc agtggttgca tcgtttgtgt ttcacatgaa acaatttgca 60

aagtgtgcga catatttaca gacagtttca gttgcgtaat taaggtgcac aacgagaata 120

<210> 248

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 248

cacttgcgac agaatgaatg tagtgcaggc tgaattctgt aattgcagca aacagcctgg 60

cttagcaagg agccaacata acagatgggc tggaagtaag gtgccatgta atgataggcg 120

<210> 249

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 249

cacattcaga ctcactttga gagcaagatg gaaattcctc ctcgcaggcg cccacctccc 60

cccttaagct ccgcaggtag aaagaaagag caagaaggca aaggcgactc tgaagagcag 120

<210> 250

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 250

cactggaacc tatttcatta atactggagc ccacttcatt agtactggaa cctacttcat 60

taatattgct tgagctggct tcttttgcaa cattttctct aatgttatta cggctaattg 120

<210> 251

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 251

cacttttaca tatttgcgcc tcatgaggat cactggccag taagtctatt ttctctgaag 60

aaccagaata ttcatctacc tcatttagaa cgtccaatac atcagctact ttggcatttg 120

<210> 252

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 252

cagtgcggcc ttctggattc tggcttatag ggtattcact acttttctgt gaagttaata 60

ctgcttttgc tggaatgaga tgcctgctct actttactgc tttgttctga tagtgataat 120

<210> 253

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 253

cagaaggtgc gagatacaga atttatcatc ttgcaacttc tgcatcttgc agttgctctg 60

tgcgagctaa catacagtta gcagcgacaa tgctgcctca gtatcaacaa ctaccggtac 120

<210> 254

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 254

aattagaaat ttcttctatt ttttgatgta cttagagctt tttgagtgta gaattttaaa 60

tggcaggatt ttacagtgtt tacatgcaag tgcattttat aagtgttcta tatgtgtaaa 120

<210> 255

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 255

cagaggttca gatgttgcag cagactataa acgctgcaac ttgctgtgtc gcagacttct 60

cattggcagg actggattta ctttcatgtc acactgcatg atttgcttcc ttgctttggg 120

<210> 256

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 256

attggtggga ggaggaggag gagtggatgg aggagggtcc gaaggagtag cgttcgtgac 60

tgtcatctgc agagggacga gggcccatca gtaccagggg tggcggggag ctctggagac 120

<210> 257

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 257

gcaataagag gcgttgaagt aaccggccat cactacctgc ttctgcccaa acacagagcc 60

gatattttcc tttatgctgg ggcttccacc tgtgcatacc acaggctgtc gttttccttg 120

<210> 258

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 258

cagattctaa actgccaagt catgccacac attctctttt tacatgtccc gtgcatgagg 60

tgctggtttt gtctgcttca agaattggaa tgcgaagagg agagcccctt atcttagtgg 120

<210> 259

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 259

tgacttctct tatttattct taaataagag tagtgtagag actcccatta gagagggctg 60

agttgaaaac gtgttgggta tttcatcaca gggctgagaa tctgagtctg ctaacaggcg 120

<210> 260

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 260

cagcattatt agacacttta actgtttcta gtttctcttc gcagacttct cttggaaggc 60

taggattgac tgcttcttta agttcactgg tatttgaaca cttagttgca gaaccaggtg 120

<210> 261

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 261

cagcattcag atctaccttt ttttctgtgc tgggagtccg cctatcatta catgtttcct 60

tacttccagc ccatctgtta tgttggctcc ttgctaagcc aggctgtttg cttttattac 120

<210> 262

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 262

cagctgtgca tatactgcaa taacaaggta ctctgcaact gaattgtcat ttgctgcata 60

catacttcat acaccttgga ggtggtgctc aaccaactgg ctatattaga gtgcctaacc 120

<210> 263

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 263

atgttataaa ttagaataat tccatgaaga ataaaaatca tttttgataa attttccatt 60

tttcttttat tgtattacac aagcatacga atatatatat gtatacacgg atgtggcaaa 120

<210> 264

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 264

cagctttcgt tttgtgcgca gattcgcaga cgagtgattc tattgggtta ggagcagact 60

cattctgaat agaatcacct tttgttttat tctcatgacc actattagta atattcatca 120

<210> 265

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 265

caggaagtca gtttgaattt actcagttta gtgcaccaag ctacatattg cagaagagta 60

catttgaagt gcctgtgcac cagatgacta tctttgcgac cacttctgag gaatgcagag 120

<210> 266

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 266

caggtattga ctgcttttat ataactttat tgcttacacc gagtgcgtgt tttcttgcaa 60

atgcttgcta tgcacccagt acgtcacagt gttgcttaga accattgcct gttccttatg 120

<210> 267

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 267

caggtcatat gactgatcca aacttttgca aagtgcctga agcctctgaa agtggactgg 60

tgctacatac tgtttgctca cagaaggagg actccttatg tcctgcttta attgataatg 120

<210> 268

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 268

caggtcttgc tggagcccag atggagtgca tacccctatt gcatatttct tcatgtgacc 60

tgcatatttc agtgcaagac ctattagaca cagagaacaa aagtgcgtgc gattttctta 120

<210> 269

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 269

catactgttt gctcacagaa ggaggactcc ttatgtccaa atttaattga taatggaagc 60

tggccagcca ccaccacaca gaattctgta gctttgaaga atgcaggttt aatatccaca 120

<210> 270

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 270

agagggaagt taataatgcg gctgcggtgt acccgtgtgg ggtgaaacgg aaccagatgc 60

ggctgctaca tctggaaatt gggggtgggg gagtgctggg ggagaaaggc accgtggtaa 120

<210> 271

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 271

catcatctga aaccaattcc ttgtcactca gaccaactcc ctggctttca gactgatgcc 60

tcatttgttt ggaagaacca atcaagtgcg gatcctgggt gtttgtattt gcagtcaagt 120

<210> 272

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 272

acacaacaac taatgagatt ttctactgca cttttaggag attagatcct gaggaaaacc 60

atacagctga attggtcatc ccaggtaata ttctgaatgt gtccattaaa atatgtctaa 120

<210> 273

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 273

cattattact gggttgatga tgttcagtat ttgttacatc cgtctcagaa aattcacaag 60

cagctgtgca tatactgcaa taacaaggta ctctgcaact gaattgtcat ttgctgcata 120

<210> 274

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 274

cattcactga tgcttgttgc gcctataatt gtctctgctt ttttgtgtat ttacagtaac 60

atggatattc tcttagattt taactaatat gtaatattgc ataattgttt cctaggcaca 120

<210> 275

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 275

ctgacactgg gccccccagg tactgcccat ctctaccaag gcctgggccc tgtggtgctg 60

tcagggcctg ttagccacct catgcctttc cctggacccc tactgggctc acccacgggc 120

<210> 276

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 276

tattcatgct tcttatttta aaagtgcttc aaatccttca ataaggttct gaaagcttgt 60

ccgattggat ggttggaatt cccagcattt cctcataagt tgataaacct gtaaaaagaa 120

<210> 277

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 277

catttagctc acttctataa atagactggg gctgccacaa tgccctggtt ccaataccta 60

agtttgaatc catgctttgc tcttcttgat tattttcttc caagcccgtt cctctttctt 120

<210> 278

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 278

catttctatt atctttggaa caaccatgaa ttagtccctt ggggttttca aatgctgcac 60

actgactcac acatttattt ggttctgttt ttgccttccc tagagtgcta acttccagta 120

<210> 279

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 279

catttgaagt gcctgtgcac cagatgacta tctttgcgac cacttctgag gaatgcagag 60

atgctgatct tcatgtcata atgaatgccc catcgattgg tcaggtagac agcagcaagc 120

<210> 280

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 280

catttgttaa cttcagctct gggtgcgtat cgctgtcatg tcttttactt gtctgttcat 60

ttggcttgtt actcttcttg gctccagttg caggttcttt accttccatg agttgtaggt 120

<210> 281

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 281

cattttgtac ttcttcaacg cgaagagcag attgctccat ttctttctgt tccaatgaac 60

tttaacacat tagtgcaaca tatatatata tcgcagatgc aggtttataa aatgacaact 120

<210> 282

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 282

cagcagactc taactgctgc cataatgttt tcccttgtat tttacagatg ctgccagcta 60

taattttgca tgcaaggtgc ataactctcc tgaacatcta tgcgatgaag tttctatcat 120

<210> 283

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 283

ccactcctgg ttctttattt ttactggtag aactatctgc agacacctca aacttgtcag 60

cagtgcggcc ttctggattc tggcttatag ggtattcact acttttctgt gaagttaata 120

<210> 284

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 284

ccacttattt tcttagaata ttgacatact ttgcaatgaa gcagtgcaca agcttatgca 60

tatactgcat gctgctgatc ccaagtggtc caccccaact tgcgactgta cttcagggcc 120

<210> 285

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 285

ccactttgaa tgcgtgcaca aataagttta tttatgctat acatgatgaa acatcttata 60

aaggtgctgc aataccgtgc gacctgcaat cagaactaat taactgttca gcccagtttg 120

<210> 286

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 286

cccctggaat ctcagcccct tctccaagac gtccatccac cacggctccc cggggcccct 60

ctccgtctac cccccggcct cgtcctcctc cttgtcgggg ggccacgcca gcccgcacct 120

<210> 287

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 287

ctccgagcgt catttccagc gctccgcggt ctccagctgc agcccacaga gaaattaata 60

agactccaga aaaaaaaaaa aaaaaggtgc ggggggcggt gggaataaaa caaccctcca 120

<210> 288

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 288

ccctgcaagg cttttcatat aatgtggtaa attcatctgc tttctctgga tttagtacag 60

caagtggtgc gcaagtttcc attttagtgc gttccttaca ctgcgttaag ggagtgttag 120

<210> 289

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 289

ccgcagtata gctcttcttc cccagtccga ccagaatata taattgtcat aaacagccaa 60

actgaggaaa gtccctggcc cagatttaac tatcacctga aataaattaa aatactgtat 120

<210> 290

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 290

cccttaccca attcaatgta gacagacgtc ttttgaggtt gtatccgctg ctttgtcctc 60

agagttctca cagttccaag gttagagagt tggacactga gactggtttc ctgcttgcca 120

<210> 291

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 291

cccttcttgc tgcccatcat tagatgatag gtggtacatg cacagttgct ctgggagtct 60

tcagaataga aactacccat ctcaagagga gctcattaag gttgttgatg tggaggagca 120

<210> 292

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 292

ctgacattta gtttcacatg taaggtaaat ccgaatggca tgagaacctt tctactcaca 60

ggtatctaaa gactcgtctg aatcatcagg gcagtcaggg tccccatcac acagccagct 120

<210> 293

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 293

cctctgcgtt ttcctctagc agagcagact tacatttagt tttaactgct gacttgatgg 60

gtgcaagtgg tggtatacga tatgggtttt gttgcagtcc atgtttattt ggagtaatga 120

<210> 294

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 294

atagtacaaa aaaactagct cagaaaaggt caaatcctcc taaatctagt ttttcttaac 60

atctggcttc ttacttttgg gaacaaggaa aacattgcca tctcttgttt gctgcaggga 120

<210> 295

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 295

cctgagatgc atgactactt cccataggct gttctaagtt atctgtgctc agatatggag 60

agtgctctgt attaacagtc tgaactactt cttcatattc ttgcgcagat atttcaggat 120

<210> 296

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 296

gcaggtagtc tgggtgctga agggtgctcc gaggtggcag gctgtggttc cagtagtcag 60

ggttgtcaaa cgctttcttg gccttctctg gcattgacag tatgttgttc ttcaggtact 120

<210> 297

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 297

cctgggttat gaaggactgc aactgcagct aataatggag ccacataaca cattctgcct 60

tacttgctgc atatgtggtc acactttgtg gagacaggtt ccttgatcaa ctccagacta 120

<210> 298

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 298

cctgttgttc tacaatgtac acatgtaaca ccactgcgag ataagtcagg tatgatttgc 60

aacaatgctt tttattctta gaatactaga aatgttaata tgcattgcac ttaacaattt 120

<210> 299

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 299

cctttgcttc tgaattacat tctgacataa gtgcgaacaa aatggacatt ctaagttatg 60

aggtgccaga catagtttgc cactgcatac tgtgcgtgcg tgtcccagtt ggtactggaa 120

<210> 300

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 300

tccttcaata cgtttcttaa taacaactgg acttggtaag aatcgcgcct tcaactgctg 60

agttacctaa aaaagaaagt agatagtatt tttatataaa cacataaaaa ttcgtatctt 120

<210> 301

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 301

ccttgaatat agattgcata ccagtgctgc ataatgatta catgaactgc tgggcaggac 60

tcttaggtcc aatttctgct cacagttttg gaggtagctt cagaacagct tctgctaagc 120

<210> 302

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 302

cgcttctgag ttttacctca gtcacataat aaggaatgca tccctgtgta agtgcatttt 60

ggtcttctgt tttgcagact tatttaccaa gcattggagg aatatcgtag gttgcaatgc 120

<210> 303

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 303

cctgttctct tccacatcac taaactgact ccagctgtat cctttctggg aaagcttgta 60

ggagagaaag tcaaccacca gctcccggtt gctctgagac atttttataa tagggatggg 120

<210> 304

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 304

cttgctattt atatgtgtac tagtcaataa acttatatat tttctcccca ttgcagcaca 60

actaaggaac gtcaagagat acagaatcca aattttaccg cacctggtca agaatttctg 120

<210> 305

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 305

ctacagatct ttcagtttgc tgcacccttt ctccacttaa catgagatct ttggggtctt 60

cagcattatt agacacttta actgtttcta gtttctcttc gcagacttct cttggaaggc 120

<210> 306

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 306

ctactggcac ttttgttgaa gtgcttactg tgcattacaa gagtgctact gtgcatgaag 60

ataactgcta tactgctgcc agtagtgctt ctcataactt agaatttgat ggcagtgatt 120

<210> 307

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 307

agtggtcctg tgtatatagg tatagaaaaa gtagctcact taatcctttc tcgccaggag 60

tagggatttt cccggaacga catccattgt cggcaatgga cgcaccaaaa taacgccggc 120

<210> 308

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 308

ctagtgattt ttgcctataa gcagagcaga atgtgtgcag ctagcagacc aatcatgatg 60

tgcgtctgaa gtgcaatgat agatttatcg cttctgtgac agacagtgaa aacactgctc 120

<210> 309

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 309

ctattgagac tgtggtgcca cctaagctct taagtgataa tttatgtaga ctgcctgtgc 60

atctctgcac atctgcaagt atcgcagaga aagtttgcgt acatgtgcat gtagtgcaag 120

<210> 310

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 310

ctattggatc ctgcgagagg ccaacatttt ttgtgctttt taagacacgc tgcaactgcg 60

caggtattga ctgcttttat ataactttat tgcttacacc gagtgcgtgt tttcttgcaa 120

<210> 311

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 311

ctcagatcca gttggtgctt aggaaggcca tggaatctgc tgaactgcag gaacaaggtt 60

tatcaaggga tgtcacaacc gtgtggaagt tgcgtattgt aagctattca tgctgcgtgc 120

<210> 312

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 312

agaactggag atgtgttctc tccgcatttc aagagagtta gactgtccac ctttattcct 60

ggtggaagac tctgaagaga tgaagcaata cctgaactcc caataggttg atataaatca 120

<210> 313

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 313

ctcctataat tagattttca gttacatggc ttaagttggg gaggcttgcc ttcttccgat 60

aggttttccc tgctattttg tcttcaatat tactctctac tgatttggag tgaactcttt 120

<210> 314

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 314

ctcctttctg gacgcttttg cttgcaacag cagaactttc cttaatgtca ttttcagcaa 60

aactagtatc ttcctttatt tcaccatcat ctaacaggtc atcaggtgtc tcagaactgc 120

<210> 315

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 315

ttctgggact ctttgagctt ctcagccaag acgttgatgg tgttgggctg cagcactgac 60

agttgcccat cagcagaacc gctcaatgcc cctggcttcc ctgttccctt ccccttatac 120

<210> 316

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 316

ctcttcggta accctgagcc tgctgtgtat gggtgtgcgg gctaggactc ctgctaagct 60

ctcctttctg gacgcttttg cttgcaacag cagaactttc cttaatgtca ttttcagcaa 120

<210> 317

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 317

ctgtgctaga agatagtacc aagcaagtct tttcctgcgt attgttttgc agtaacgaac 60

attcagacca gctcacaaga gaagtgcata ctgctatacg tactccagaa catttaatat 120

<210> 318

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 318

ctgcctgaac ctggctctcg agcttcaaga acaacattga ataagatttt cattcgctgc 60

tttcttatgt tctttttact gttgaggggg aggtagaaaa ggggaaaaat tagaataggt 120

<210> 319

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 319

ctgaggtgga cctaatagga tttgtcgttt ctgttgtgaa tgcaacaggt aatgcacaat 60

atagttaatt gcagatattg attcttttaa tgcacattgt cgcagagcat ctcttatgat 120

<210> 320

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 320

ctgatgttcc tgtgtgcaca aatatagaag tttgttctac ttactcctgc gattcagtgc 60

actactttga aacagaagca gtagtgcttg cttgcgcttt tatggaagat gatgaactga 120

<210> 321

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 321

aacgcgcaaa agaacttgaa aaccgacaga agaaactgga gcacgccaac cggcatttgt 60

tgctcagaat acaggtacgc agcctgagtt gtgtaaagtt tactgctttt taccgacttc 120

<210> 322

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 322

ctgcctgctc tgctttcttg attgcatcct caggatgaag gcctgatgta ggtctccttt 60

tacgctttaa tttatttgtg aggggacgct cttgtattat ctgtggctca gtaactgctg 120

<210> 323

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 323

ctgcgtgttc tcattgccag gtatgtgttt gtctacaata ctgatggctt ttatgacaga 60

gtgtaatttt atttcattaa ctagtatcta ctgctggctt tgttttgcga atgaacacat 120

<210> 324

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 324

ctgctcatgg cactgcactg aatgtttcta ctgaagctct gctgcaagct gtgtgcctgt 60

ttagtgatat tgagaatatt agtgaggtgc cttctgcaga ggtacatcca ataagtttat 120

<210> 325

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 325

ctgcttttgc tggaatgaga tgcctgctct actttactgc tttgttctga tagtgataat 60

tcaggttaga atactgattt ttttctgcag catcaatcta tgatacacaa attgggcaga 120

<210> 326

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 326

ctgtttcatt tatgctttgg ctgcccagca agtatgattt gtcctttcac aattggtggc 60

gatggttttc tccttccatt tatctttcta ggtcatcccc ttcttgctgc ccatcattag 120

<210> 327

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 327

cttaatatta acttgctagg tgcataccag cttcatagac tgcggttctc tttgactcac 60

ctgcaataag ttgccttatt aacggtatct tcagaagaat cagatcctaa tgcatttccc 120

<210> 328

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 328

cttacaactc cctatacatt ctcattccca gtatagagga gacgcagagt gcagagccac 60

ttcctgcgaa tgctgcttta taatccagag tatatacatt ctcactgaat tattgtactg 120

<210> 329

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 329

cttactccaa agattcagaa aactactttg tgccagaagc agtagtgctt gcttgcgctt 60

ttatggaaga tgatgaactg acagattcta aactgccaag tcatgccaca cattctcttg 120

<210> 330

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 330

cttatgatct ttaactgttc tgggtcacaa atttgtctgt cactggttaa aactaaggtg 60

ggagcagatt ttttgctaga tttaggacca ataagtctta attggtttga agaactttct 120

<210> 331

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 331

cttatgatgg aagggtagct gttagaaggc tggctcccat gctgttctaa cacagcttct 60

agttcagcca tttcctgctg gagctttatc aggttatgtt gcatggtatc cctctgcttc 120

<210> 332

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 332

cttcaagtaa atgtcatgat tctgttgttt caatgtttaa gatagtgcat cataatgata 60

tgcctgtaag tgtgctgcat aattgctgcc aactgatatt actgcataat attgtgctga 120

<210> 333

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 333

cttcagagaa ttctttgcca cgtatttcta gcctacctgc atcagagaag ccatttgctg 60

aggtgccagt ggttgctaag agagatgaag agcagcatct tgaatctcat acagactgca 120

<210> 334

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 334

cttcagagac gcttgtttca ctctcacacc cagatgctgc ttcaccttaa ataactgcaa 60

cagaggttca gatgttgcag cagactataa acgctgcaac ttgctgtgtc gcagacttct 120

<210> 335

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 335

cttccaattc actgcactgt gaagtgcaca agctagcaga acattttgtt tcctcactaa 60

ggtgatgttc ctgagatgcc tttgccaata ttacctggtt actgcagtca tttaagctat 120

<210> 336

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 336

cttctcctaa ttgtgagata tattatctgc gtcctttatc actttgtatg gcctgcagga 60

agtctgtttc cacacctgtc tcagcccaga tgacttctgc gtcttgttgc ggggagtgcg 120

<210> 337

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 337

cttctgtgaa aagaagctgt tcacagaatg attctgaaga accaactttg tccttaacta 60

gctcttttgg gacaattctg aggtgctgtt ctagtgctga aacatgttct aataatacag 120

<210> 338

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 338

cttctgtgag tcagacttca ttacttgaag ctgctgcatg gcttagagaa ggaatatttg 60

atggtcaacc agtgcgaata aatactgcag attatgtagg tgcttatttg tatgtgcatt 120

<210> 339

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 339

cttgaccatt ctgctccgtt tggttagttc cctgatttat catttcagga gtcttttgaa 60

ctgcctgctc tgctttcttg attgcatcct caggatgaag gcctgatgta ggtctccttt 120

<210> 340

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 340

cttgcccctt tcgtctattt gtcagacgaa tgttacaatt tactggcaat tgcgttttgg 60

atagacctta atgaggacat tattaagcct catatgttaa ttgctgcaag caacctccag 120

<210> 341

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 341

cttgccttgg caagtaagat gtttccgtca aatcgtgtgg cccagactct tccagctgtt 60

gctcctccac atcaacaacc ttaatgagct cctcttgaga tgggtagttt ctattctgaa 120

<210> 342

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 342

cttgctcgct ttggaccttg gtggtttctt ccattgacca catctcctct gacttctgca 60

tcatgctgaa agtgccctgc cacaacccat caggataaga gtgcgagaag cttccttcaa 120

<210> 343

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 343

cttggcatta gataatctgc agtgcctgag caagcctcag tcaattaata ctgtatctgc 60

acatttacag agtagtgtag ttgtttctga ttgttgcaat agtcatataa cccctcctgt 120

<210> 344

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 344

taggagatga cataccttgt aggggacaaa ttcatttctc ttgctcctca ggtaagtgga 60

caggtttcca aatttgcaga attccacaat caccatgagt ggccctgcag gcagcatgtc 120

<210> 345

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 345

ctttacctcc acctgttagt cccatttgta catttgtttc tccggctgca cagaaggcat 60

ttcagccacc aaggagttgt ggcacctgct acgtgccacc cattgcgtgc tgcgaactga 120

<210> 346

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 346

cttttgaatt gtggatattt aattcgagtt ccatattgct tatactgctg cttataggtt 60

cagctttcgt tttgtgcgca gattcgcaga cgagtgattc tattgggtta ggagcagact 120

<210> 347

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 347

gtgcaagtgg tggtatacga tatgggtttt gttgcagtcc atgtttattt ggagtaatga 60

gtccagtttc gttgcctctg aactgagatg atagactgca cctagagcct cctttgatac 120

<210> 348

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 348

gtgcagaaca ggcttcacct tgcaacgtaa tgctggtgct tggttgcact gtgccgcaga 60

ctgatgttcc tgtgtgcaca aatatagaag tttgttctac ttactcctgc gattcagtgc 120

<210> 349

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 349

gtgcgttcct tacactgcgt taagggagtg ttagaggaat ttgatttaat cagaactgag 60

catagtcttc actattcacc tacgtctaga ctgcatgtat ctgcaatact tcctcgtaga 120

<210> 350

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 350

gaagaagaga ggaagagaga gggacagggg aatggagaga aggtgcatct agttattgca 60

gaatattggc ttttattcaa tgcacagact ttctgcaagg aagagctttt cgcagacttc 120

<210> 351

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 351

gaagaatgtt gaagatctgc tgcacactag gcagacctgc gtaatatcca atgttgcaga 60

tgctgctgca tacccactgc ctgttgctga agatatttgc gttgaggaac ttgtgactag 120

<210> 352

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 352

tccttatgta ggactagcca caccaattgt gcttacagtt tattttgttt tgtatttaca 60

ttcatataac atagatacca gtataaaaaa acttgtcaag aaaacatctt ttccacaaca 120

<210> 353

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 353

gaagctgcta cagcagaaac tatatgactg aatgaatatc tctggttagt ttgtaacatc 60

aagtacttac ctcattcagc agcagacttt ctttaataga ctgggtcacc ccttgcgaga 120

<210> 354

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 354

gaagctggcc agccaccacc acacagaatt ctgtagcttt gaagaatgca ggtttaatat 60

ccactttgaa tgcgtgcaca aataagttta tttatgctat acatgatgaa acatcttata 120

<210> 355

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 355

accccggggc cccgagcccc gcatcttctc cgagcctcct ccggtgccgc tgtcccgagc 60

ggctcagtcc accgcttcgg cctcgcagag cggcgaaggg agactcggga gtcctccttg 120

<210> 356

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 356

gaatcagatc cttgctgctt tcccccctgc tgcttgctca attgcagttt tcttaattaa 60

aagggtttgc tgcatgtact tgttgtgcaa cagatattca actagtgcta tttactgaga 120

<210> 357

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 357

gaatctgctt tctgcacgaa agctgaacct ataagcagca gtataagcaa tatggaactc 60

gaatttgcta tccacaattc tgcagcacct tgcaagaata ggctgaggag gaagtcttct 120

<210> 358

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 358

gaaattccag tcaacagtac tagtctcagt ttatattcta atcaaaattt cacatacctg 60

gtcagctaac ataagtacag ttttcattgt gaaccttctt gaacagaaat tgaagaggtc 120

<210> 359

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 359

gaccctagga gggtgaattc tgcatttcag tgcactgcag gatggcgtcg tctctgccct 60

ggctgtgcat tattctgtgg tgagtaagat cctttttcct gatttttctt tttatctcag 120

<210> 360

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 360

gcccgtggcc aaggccgagg ggagcccgac cgccatcctc atcggctgcc tggtggccat 60

catcctgctc ctgctgctca tcattgccct catgctctgg cggctgcact ggcgcaggct 120

<210> 361

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 361

atgacttttt cttacagtag ttgtatagac agcttctgga tcatcctcta taactcggga 60

caggccaaaa tctgacactt tacaaacgag attgctgttg acaagaatat tgcgagctgc 120

<210> 362

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 362

gactcccaga gcaactgtgc atgtaccacc tatcatctaa tgatgggcat ttagaagggg 60

atgacctaga aagattgctg gaaggagtgc accatcgcca ccaattgtga aaggactgct 120

<210> 363

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 363

gagtgcaaca atttatatct gtcagtgaat ccactaggac tgctcccacc agttcagaag 60

attatctcag actgtgccga cgttgtacta catctctgat ctgcgaacag gagagttccc 120

<210> 364

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 364

gagaagactt ctgaggctac agtaggggca tccataggga ctgacaggtg ccagtcttgc 60

tcacaggaga gaatattgtg tcctccctct ctgacagggc acccaatact tactgtgcca 120

<210> 365

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 365

cacaatgccg ctattaagac tctcatatct tctgttttct ctctcatacc tggaaggcaa 60

taaagcatct gggactcatg ccttcaagtt gaaaagacat cactgaggga gtgacattga 120

<210> 366

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 366

gagattgcga tgctgcagta caacctgctg ccagtcaggc acagcagtgc cctacaactc 60

atggaaggta aagaacctgc aactggagcc aagaagagta acaagcctgc tgaacagacg 120

<210> 367

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 367

aatctactta ctaaaaaaga ttatgcagag catcggaaca gctcaaaccg tactcttcac 60

acacggagtc actagggggc agctgaacaa aaggaatgag gctttgcaac tgaaaaaaaa 120

<210> 368

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 368

gagccacagg accccaagaa tgagcttaca aagtggcctt tccaggccct gggagctcct 60

ctcactcttc agtccttcta ctgtcctggc tacttgctat tttatgtaca tcagcctgaa 120

<210> 369

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 369

taaataaata aataaataaa gtaagaaaat tgtctcccat tgtatatctg cgtgttgtct 60

gtgtgtaggc gagatcttag aataagaaat actaaatgac acagctttgt aatacattaa 120

<210> 370

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 370

gtgcattacc tgtttaatat ttagctcctg gaaaggatct ttcaatctca gtttggtgat 60

cctatattgt ttgaaaaatt ttattctctt ttgagttatt gaatcctcac ttttgataca 120

<210> 371

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 371

tgactcatca gaagtctcag cgttcggtta aagtttaagg aagtccattt accagagatg 60

cgccagcctc caagctttaa aggagagaga gggggctgag cataaggatc cgtggagccc 120

<210> 372

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 372

gagggaaggc tcagatacaa acacagctat ttgcaagtca ttcctccttt tggccagaac 60

caccatcttt cagtaatttg cctgcatgac gaacactgcg ggtgcgagga gaggcacctg 120

<210> 373

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 373

gaggtaaggt tacttttcag catcaccaca cattttggta gcagactatt ttgacagtcc 60

agtatcaagg tgctagcttt tatactgctt ggatagttga ggtagtatgt gaggttgcgt 120

<210> 374

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 374

gagtagcatc accttcaaga aaggtacaat tcaacctgca cactgctcta agagtaatcc 60

tgctgcatca agaagtgcct acttcaattt ctgcaataac tgtcaatcca gactctgaag 120

<210> 375

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 375

gataggcgga ctcccagcac agtgctgcag gtagatctga atgctgatcc cctgtgtgag 60

agtgcagaat ggaataagca gtgcctgcca tgctcagaga atcctagaga tactgaagat 120

<210> 376

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 376

gatatctctc tgctgcttgc cttgattctg gtattgagcc agtattgaag aatgttgaag 60

atctgctgca cactagtttt tcctgcgtaa tatccaatgt tgcagatgca aatgcatacc 120

<210> 377

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 377

gatattcaac acttacactc ctgccctgtg tcaagctgaa aagcactgct gattttcaat 60

agctcttcaa caagttgact tgctctcgta ctttcttgta ggctcctgaa atttgcttgt 120

<210> 378

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 378

cgaggggaag gaaaagggag gcagcgcgag agagccgggc agagtccgaa ccgacagcca 60

gaagcccgca cgcacctcgc accatgagat ggcgacgcgc cccgcgccgc tccgggcgta 120

<210> 379

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 379

gatgacacag ctgctgcaac acttgttctc tgtgtttctg acataatttc attgagcgca 60

aatatatctg tgccttctag caattgcact agtagtgcag ataccctgca agtggccatt 120

<210> 380

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 380

gatgatgaag tgcgaggaac gggcttggaa gtgcataatc aagaagagca aagcatggat 60

tctgccttag gtattggaac cagggcagag tgtttgcccc agtctattta tagaagtgag 120

<210> 381

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 381

gatggacatg gctctgatga tagttgcaat aagattaatg acaatgagat tcatcagttt 60

aactgcaaca actccaatca agcagtagct gtaactttca ctgcgtgtga agaagaacct 120

<210> 382

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 382

ttggtggcag acatgttgca ctgaagcaga ggagatgtga ggttcatggt agtggatgcc 60

aagtttgggg gtggcgtcat ggtggcttgt gcttgaggag tcccagctaa gggatgagat 120

<210> 383

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 383

tcaccccaga actgcatgct gcttggagga cggaagaaca cagatgttcc cttggaagga 60

tatttagtaa caccaataca aagaatatgc aagtaccctc ttattttgaa ggtattttat 120

<210> 384

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 384

gattgttttc tagatttctt cctctaggtt attaattgac aatacctaca ttgcactctt 60

tccagaatgt tgttaagtct tagtcattag ggagatacat atggatacac tcactgcttc 120

<210> 385

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 385

ctggcagaaa cttcagctgt gtgttctgga atactcacgt gagggaactt actttggcca 60

gcattgacct tcaaagtaag agctgccccc acttcctagg tctatcagtt agggttcaga 120

<210> 386

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 386

gattttctgc ttgaagtctc ccttggtgct ctgccatgag cactgcatta tggtaatttt 60

tcacctgaga agagcagagc accattttgc cgccaccaat tgagcaagat gctgattcat 120

<210> 387

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 387

gtggcacccc tgaagtcgcc ccaggttggg tctcccccgg gggcaccagc cggaagcagc 60

cctcgccaga gccagcgttg gcaaggaagg aggactgggc tcctccccac ctgcccccca 120

<210> 388

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 388

gctgctactt gtgggatttt tagcacagca agtggtgcat ctgtccaggt atcagatgct 60

tcattactgc acgcaagaca agtgttttct gtgctagaag atagtaccaa gcaagtcgcg 120

<210> 389

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 389

cagtttatcc acagggatct ggctgccaga aacattttag ttggtgaaaa ctatgtggca 60

aaaatagcag attttggatt gtcccgaggt caagaggtgt atgtgaaaaa gacaatggta 120

<210> 390

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 390

gcaagatggt gcagagcttt atgaagcagt gaagaatgca gcagacccag cttaccttga 60

ggtgagagag taagaggaca tataatgagg cttgatgatt attcaaggtg agaagctgtt 120

<210> 391

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 391

gcaatgtgcg agaggaagaa aaggaagcag ctgcatatgt ggaggcccaa ctgcagagac 60

tagaagcctt attcacttgc attcaggagg aatttgaaga acatgaaggt tgcattagtt 120

<210> 392

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 392

gcagaatcca aactgatttc atccctggtt ccttgagggg tgatttgtaa caattcttga 60

tctcccacac tatagggtgc agacagagtc ctaataagaa acactagtta catgtatgca 120

<210> 393

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 393

gcagggtagg gggggagtgc aagtgcataa atgaggctca ataatttatt ttgcaattgc 60

gctattctta gtgaataagt tcaactttga gctgttatga ctgagtcaac ataaggcctc 120

<210> 394

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 394

gcatttgtta ctgagccaca gataatacaa gagcgtcccc tcactgctaa atttgcgcgt 60

tgcaggagac ctacatcagg ccttcatcct gaggatttta tcaagtgcgc gctgttatga 120

<210> 395

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 395

gccactttgt aagctcattc ttggggtcct gtggctctgt acctgtggct ggctgcagtc 60

agtagtggct gtgggggatc tggggtatca ggtaggtgtc cagctcctgg cactggtaga 120

<210> 396

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 396

gcctggccag gggttgtgct gcagagcttt caattttatt tttgctaagt atttattctt 60

tgatagattt aattacaagt cttcagaatg ccagagatat acaggatatg cgaattaaga 120

<210> 397

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 397

gctcattgca ttcacttccc tgcgctgcct accactgcta ctgcttatga ccaagatttt 60

tggctgcact ataagataag gaatccagca attattatta aatactttgc tgccctgaga 120

<210> 398

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 398

gctcctccac atcaacaacc ttaatgagct cctcttgaga tgggtagttt ctattctgaa 60

gactcccaga gcaactgtgc atgtaccacc tatcatctaa tgatgggcat ttagaagggg 120

<210> 399

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 399

gctcttttgg gacaattctg aggtgctgtt ctagtgctga aacatgttct aataatacag 60

taatctctca ggatcttgat tattgcgaag ctgcatgtaa taaggtgcaa ctacagttat 120

<210> 400

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 400

gctgcagcat gtcacccagt acaacattca tgcgtggaat acagtgatac tgactttcaa 60

tcccagtgca gtcttttata tgatcatgaa aatgccagca ctcttatttt aactcctctg 120

<210> 401

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 401

gctgtaatga gctggcatga gtatttgtgc cacatggctc cacatgcaag tttgtgccag 60

aactaccctg atacttttct ggatgcctct cagctgcacg cttctcagtg gtgttctgct 120

<210> 402

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 402

gcttacaatt acttccagga agactttgtt tatagacctc aggttgctgc acccctaatc 60

taagcatagc attcaatttt ggccctctgt ttctacctag ttctgcttga atgttttcat 120

<210> 403

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 403

atggggacta cactctaata gccaagaatg agtatgggaa ggatgagaaa cagatttctg 60

ctcacttcat gggctggcct ggaattgacg atggtgagta actgacactt ttgtatgtgg 120

<210> 404

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 404

cagggtcgtg gtggtgaagg aaagcacctt ttgagtggag ttctgtgcga cactctgatg 60

aaccacctgt ggtcacaaca gaatgcgaaa tgcccaaatg caatgaacac ttccacaagc 120

<210> 405

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 405

ggtgcatggg tagttagcta tttctgtaag tataatacta tttctcccct cctcccttta 60

acacctcaga attgcatttt tacacctaac gtttaacacc taagggcaga gctgatatcg 120

<210> 406

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 406

tgaaattcag gtgggggggc tcacctgcaa tgcccgttgc tcccggctga gctgactgga 60

atctgcatac agttcggtag tgacacattt gaatcggtca cccacgtaac ccgctgagtt 120

<210> 407

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 407

ggaagccatt gtcctctgtc caggcatctg gctgcacaac cacaattggg tggacaccct 60

ggatccccag gaaggtgcga gcattctgcg tgtctgcgta ggactactgg aactgtcact 120

<210> 408

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 408

ggagacaatg aaccactgcc aattgtgcca ttaattctgc gagatgatgt cagctgccct 60

aagaatgtgg gatacatact actgaatgca aaggacacca cacacacgca tgtgcacaca 120

<210> 409

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 409

ttttctgttt tccaaataaa tgtacaactg attatccctt tttttttttt tccaggaatc 60

taggtaaaaa tggcttatct aacagtagca ttttgttgga taaatgtcca cctccaagac 120

<210> 410

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 410

ggagcagatt ttttgctaga tttaggacca ataagtctta attggtttga agaactttct 60

tcagaagctc caccctataa ttctgaacct gcagaagaat ctgaacataa tgccaacaat 120

<210> 411

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 411

ttgctgcagc agctcactat taggaaacct ccgctcacgg gcttcagact ctagtgccct 60

cagttcttca aggcctggaa gaaaaatgag ggcagcaaag agtaggcagt attgaataga 120

<210> 412

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 412

ggcctttctg ctgacaagtt tgaggtgtct gcagatagtt ctaccagtaa tgcttgcgaa 60

ccaggagtgg tgcggtaaga aacatcaatg ttgcgatgct gtggtatctg acatctacct 120

<210> 413

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 413

actgctgctg tggccagtgg ctccattcac cgcggggctg tctgccaggt gccaggatgg 60

gttgccattg atggcactgg gggtctccat ctccgattca gtcccttctg gggcctcagt 120

<210> 414

<211> 3

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 414

<210> 415

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 415

ggttgctatt ctacctggtt tagcagaatg acttagtaat tgagaatttg acaatagcgt 60

tatacctttg ccctgagatt tactgctctg tacctagcat tctgcctcat acaggcaatt 120

<210> 416

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 416

tcctcccctc tcccccatat aggaagcttg ctggactttc tgaaaagtga tgagggcagc 60

aagcagccat tgccaaaact cattgacttc tcagcccagg tgagagccta acgaggaaac 120

<210> 417

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 417

ggtcttctgt tttgcagact tatttaccaa gcattggagg aatatcgtag gttgcaatgc 60

ctattggatc ctgcgagagg ccaacatttt ttgtgctttt taagacacgc tgcaactgcg 120

<210> 418

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 418

ggtgagagag taagaggaca tataatgagg cttgatgatt attcaaggtg agaagctgtt 60

ttagactctc tggccatcac aggaaggagt atgttgtgct gctgcatttc tctgcaggga 120

<210> 419

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 419

ggtgatgttc ctgagatgcc tttgccaata ttacctggtt actgcagtca tttaagctat 60

tcttcaatga taattgcttc tcctctgtgt tcttagacag acactcggta gcaacggtgc 120

<210> 420

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 420

gcagccagca aatgaacttt ctgcattggt cagaatttcc atcatttcac tgttaatgag 60

gaaagtacag ttctttagct accatgaaag tcaaacatat cctaagcctt ttggaaaaag 120

<210> 421

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 421

gttgcaatag tcatataacc cctcagatgt tattttccaa gcaggatttt aattctgccc 60

ataatttaac acctagccaa aaggcagtgc ttacagaact ttctactata ttagaagaat 120

<210> 422

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 422

gtaacagtag catgtctaac agctattcct accattctga tgaggtatat aatgattcag 60

gatatctctc tgctgcttgc cttgattctg gtattgagcc agtattgaag aatgttgaag 120

<210> 423

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 423

gtaagtattt ttgtttaaca ttttgcgagt caatacttta gcttttgcaa aatggtctat 60

agacttttga gtgcttgcac tgatattatt tgcctttgca acatatatga aatatttctt 120

<210> 424

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 424

gtaagtgttc agcagaacct ttcgtgttgc caatcactat gcagagcgtg tttattcagt 60

agacttggta tgctaacaat taagagtgtt attgcctatg tcttttcagc cagcagagtg 120

<210> 425

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 425

gtaataagtc ttactgcatg aagcggccca tctctgctgc ggggagtgga atacagagtg 60

gtggggtgag agcagagtca acttgaggga gggagcttta cctttctgtc ctgggattct 120

<210> 426

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 426

gtaatacttc tgcttgcgaa cagttaactg ctacttgcac ggagctgcat attgcagatt 60

ttgagacttc tgatacattt tttcagactg caagtgggaa tgctattagt gtcgcctgcg 120

<210> 427

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 427

gtacactgct ctgctcattc ctggtacagg tgccaagctt ctggtaagtt aatgttgcct 60

caaggaatat tataagaagt atatatggag gccatcgtat attctgttgt atacctagta 120

<210> 428

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 428

gtagactgcc tgtgcatctc tgcacatcaa tgcgtatctt tttgtgcgtt tgcgtacatg 60

tgcatgtaga tgcagtgcca gctgcaagtc ctgcaacttg ttacactgct cagtcccctt 120

<210> 429

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 429

gtagttaatg tgcagcagag gttgcttcag ttttggtttg ttataattgt ttttattgtg 60

tgatacatgt ttacttttgc ttggcagact gcagagtgtg tgtttatttt gtgtagctgt 120

<210> 430

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 430

gtatagggaa gcttcataag tcagtctcat ctgctgctac ttgtgggatt tttagcacag 60

caagtggtgc atctgtccag gtatcagatg cttcattaca tgccgcaaga caagtgtttt 120

<210> 431

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 431

gtatggttgc gaacagtcaa gcaattgttg gccagttctg tgcttttcct cctgaagaga 60

aacttgacac catggactgc attgcttgac catcatcagt cagctaacat gtatgatgcc 120

<210> 432

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 432

gtatgtaagg tcaattctgt tcatttgcat aggagataat cataggaatc cctgcttaat 60

acactcttgt gctgacttac cagatgggac actctaagat tttctgcata gcattaatga 120

<210> 433

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 433

gtatttattc tttgatagat ttaattacaa gtcttcagaa tgccagagat atacaggata 60

tgcgaattaa gaagtgccaa aggcaacgcg tctttccaca gccaggcagt ctgtatcttg 120

<210> 434

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 434

gtattttaca gatgctgcca gctataattt tgctgctgcg gtgcataact ctcctgaaca 60

tcttgcagat gaagtttcta tcatcctgcg tatgggctac agtgcccgtg cctgcagact 120

<210> 435

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 435

gtcacagggt tatttcagtg aagagcagtt aagagccttg aataatcaca ggctgctgtt 60

gaatgataag tgccaagctc agatccagtt ggtgcttagg aaggccatgg aatctgctgg 120

<210> 436

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 436

aattagtcac ctcacgactt tatttgaatg aattaatgag aagctaaata aactagcttt 60

ttaaaaaata ttttcttctc tttctccagg caatgggtca ctttggggcg ctgcagaaca 120

<210> 437

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 437

gtccagtttc gttgcctctg aactgagatg atagactgca cctagagcct cctttgatac 60

tacatttggc attatcaact ggcttatctt tctgaccaac cacaggtgcg cctgcagtga 120

<210> 438

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 438

atttctactc tacgaaatgg acaaattaaa agtgcaccct atgcctgttc tggtctaaga 60

gagaatacat gcacagcgtt atgtttgtct gtttcctttt atatgaataa tcaatatgga 120

<210> 439

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 439

gtctgtcact ggtttgcact aaggtgggat gcagatttta aatagattta ggaccaataa 60

gtcttaattg gtttgaagaa ctttcttcag aagctccacc ctataattct gaacctggca 120

<210> 440

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 440

ggactaggag ccagctttgg ggaccccggg ggactctctt ccaccaactg gctagggact 60

cgcaggacca cctgccccaa cctcgcgatg ccaagccaac aggggcggcg agggctctcg 120

<210> 441

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 441

gtctttgcga atggcagact gacagttggt cagaagatta ttcttcatgg agcagaactg 60

gtgggctctc ctgatgcctg tacacctctt gaagccccag aatctcttat gtttgcggta 120

<210> 442

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 442

gtcttcagaa tgccagagat atacaggata tgcgaattaa gaagtgccaa aggcaacgcg 60

tctttccaca gccaggcagt ctgtatcttg ctgcaacatc cactctgcct cgaatctctc 120

<210> 443

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 443

gtggggaggc cccgccggct gggtcccacc gcccccacgc acctgcgttt tggtgactcg 60

atgccgcgcc agcttcacca ccgcgaagtt gcctttgccc agggtccgct cgatgtcgta 120

<210> 444

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 444

gtgtgcaatc ttgcaaccaa gtgtgcgtgc aatactcatt tgtatctgaa gtggaaccaa 60

atgatactga tccattagat tctgctgtag ctgctcagaa gccctttgag agtggaagtg 120

<210> 445

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 445

gtgtgcacta tgctggatca agcagatgat gtttcctgtc cacttcttgc ttcttgtctt 60

agtgtgcggt atgatgaagc tattatatta tgctatttaa atgtgccatt ttcctacgcg 120

<210> 446

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 446

gtgaagagca gttaagagcc ttgaataatc acaggctgct gttgaatgat aagtgccaag 60

ctcagatcca gttggtgctt aggaaggcca tggaatctgc tgaactgcag gaacaaggtt 120

<210> 447

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 447

gtgagccact gtgcctggcc aggggttgtg cgcagatgct ttcaatttta gcagagctaa 60

gtatttattc tttgatagat ttaattacaa gtcttcagaa tgccagagat atacaggata 120

<210> 448

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 448

gtgagccact gtgcctggcc tgatacaatt aacttgaatg ttatatatgt gacgcagatg 60

gtgtgtgtaa cacattatta cagtggatgg agaagacatc atctggatta tacatatttc 120

<210> 449

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 449

gtgctacact gtccaacacc cactctcggg tcaccacagg tgcctcacac atctgcccaa 60

ttgctggaga cagagaacac aagcagagat tagtgtcaat tcattctcct ggactaggct 120

<210> 450

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 450

caaggtccct gccattgcag atcctggagg cagctgacaa aacgcaggca ctggacatga 60

agcggcactg cctgcacatc attgtgcacc agttcaccaa ggtcagggct ctggcctccc 120

<210> 451

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 451

gtgggctctc ctgatgcctg tacacctctt gaagccccag aatctcttat gtttgcggta 60

aattaatttg cactcttggt tgcaatcagt cattgattca gtttgcttct agaagtttta 120

<210> 452

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 452

gtggggtgag agcagagtca acttgaggga gggagcttta cctttctgtc ctgggattct 60

cttgctcgct ttggaccttg gtggtttctt ccattgacca catctcctct gacttctgca 120

<210> 453

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 453

gtgttgcctc agtgctggaa tgcacctgca gttgcgaatt ttgcttatca aataacttaa 60

atgttgaagg tggttcttca gtgcataatc actctattaa agtttctcca tatctctctc 120

<210> 454

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 454

gtgtaatttt atttcattaa ctagtatcta ctgctggctt tgttttgcga atgaacacat 60

tagtgcagga atggatgaat gtgctcatca tattttctaa ttagcctgca gtggcagcct 120

<210> 455

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 455

tgagccactg ctctgggcca actgtgcttt ttgaaggcag gaataactgg ttcatttctg 60

ggtgtcccag ggagcctggt tctgagcttt acacatagca catactggaa gagcccttcc 120

<210> 456

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 456

gtgtgtgtaa cacattatta cagtggatgg agaagacatc atctggatta tacatatttc 60

gcaatgtgcg agaggaagaa aaggaagcag ctgcatatgt ggaggcccaa ctgcagagac 120

<210> 457

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 457

gtgttttctg gctgccttgt acacgagcat ctgtgcttaa atctgctatt ccattatcat 60

gagttacctc tagcacacag ctcagaatac tagttattcc accatggcat atgtttacct 120

<210> 458

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 458

gttcaagcgc atgaatatgc ctggtagaag acttcctcct cagcctattc gcagaaggtg 60

cttttgaatt gtggatattt aattcgagtt ccatattgct tatactgctg cttataggtt 120

<210> 459

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 459

gttcacattc tgcagtgact tttggacttt gtttctttaa ggacccagag tgggcagaga 60

atgttgcaca ttcctcttct gcatttcctg gatttgtgca cggagctgct gactggcgct 120

<210> 460

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 460

gttcttcaga tgctaatcac tctatttgcg tttctccata tctctctcaa tttcaacaag 60

actgccaaca gttggtatta ggaacctgcg tgtcacttgt tgagaacatt catgttttgg 120

<210> 461

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 461

gttggatttt tcgttctcac ttaattgaag tgcgttgcgc ttctattgcg ttaggtgttt 60

cctgggttat gaaggactgc aactgcagct aataatggag ccacataaca cattctgcct 120

<210> 462

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 462

gttgttgatg tggaggagca acagctggaa gagtctgggc cacacgattt gacggtgcca 60

tcttacttgc caaggcaaga tctaggtaat atttcatctg ctgtattgga actgccactt 120

<210> 463

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 463

gtttagcttg tgttgtgctt gttgctacct tggcattaga taatctgcag tgcctgagca 60

agcctcagtc aattaatact gtatctgcac atttacagag tagtgtagtt gtttctgatt 120

<210> 464

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 464

cccaaggtca agtggttggt ggaggggctg gcgctgcctc tctcctcaga ctgagtggtt 60

gtgttaatca catgagagca gacacagaat gactttgcgg aggtggagga gacctggatc 120

<210> 465

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 465

ttgcaatgga aattggttgc actgtgcctt tttctgatgt tcctgtgtgc actgctatag 60

aagtttgttc tacttactcc tgcgattcag tgcactactt tgtgccagaa gcagtagaac 120

<210> 466

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 466

gctgggcacc atgctggtgg tgcctggggc agagcctggc cttgtggggc tgtggagcag 60

ggtgaggatc tgggatctag gactgctatg caccgggccg aatcgtgata cccaagggag 120

<210> 467

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 467

ttgctatgac attgattaga ctgttgtgct tgctaacaat tttggaatgc cttgtttgct 60

tatttatctt acagcagaaa tttcctaatc tgtaatttat ctaagccttt gagtgcgtct 120

<210> 468

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 468

caaggagctg gtggttgctg ctcgccaagg ggatactcag acagccaaag cctaggcagg 60

atcagaagct caggcagcag agccaagatt tgaaccaata attttttttt tttttttttt 120

<210> 469

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 469

catagtgagg acccatgggg cttcacccag gacagcctgg ttcgcctgcc ctccgatgct 60

ggtggagggg aggcaaggca gaggggactc ctgtaaaggg ctgttttttt ctgtcctgga 120

<210> 470

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 470

taacccttta aatactgata tgtaatattt agcacattct acattgcctg tttctatgag 60

tgcggttgtg agaataatat tgcttatatg gcttattgca tattaatgtg cttctgtttt 120

<210> 471

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 471

taactaccca ttttcctccc gcaattccta gtgcatattt cagtgtccgt tcacacacaa 60

actcagcatc tgcagaatga tgcacactca aaggattaga agttgtgcac tgcatcagga 120

<210> 472

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 472

gtcttatggt gttttacctg tgctgattgg ttcttggcag cctttaaatg cctaggcaga 60

gaggaagaga gaggttccta agcttcatgg tgaatttcta agtctgtgtt gactgcagga 120

<210> 473

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 473

taagcatagc attcaatttt ggccctctgt ttctacctag ttctgcttga atgttttcat 60

cactggaacc tatttcatta atactggagc ccacttcatt agtactggaa cctacttcat 120

<210> 474

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 474

taatattgct tgagctggct tcttttgcaa cattttctct aatgttatta cggctaattg 60

tgctcactgt acttggaatg ttctcatttc ccatttctct ttcaggtgac attgaatgtt 120

<210> 475

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 475

taatctctca ggatcttgat tattgcgaag ctgcatgtaa taaggtgcaa ctacagttat 60

ttattacccc agaagctgat tctctgtcat gcctgcagga aggacagtgt gtgcatgatc 120

<210> 476

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 476

taattaccca tgtgctgagc aaggatcata tgctgttgga gctaggtcct tactcttcag 60

aaggagataa aggggaagga aagaattttg cttaagatat cagtgtttgg ccaacaatac 120

<210> 477

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 477

tacaacattc tgcagtggaa tacagtgata ctgactttca atcccagtgc agtcttttat 60

atgatcatga tgctgccagc actcttattt taactcctac ttccaaggat gttctgtcaa 120

<210> 478

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 478

tacagtcaga aatgaagaag catctgtgcc tgtatttcct catgatacta ctgctgtaag 60

ttgctatgac attgattaga ctgttgtgct tgctaacaat tttggaatgc cttgtttgct 120

<210> 479

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 479

tacatttggc attatcaact ggcttatctt tctgaccaac cacaggtgcg cctgcagtga 60

tattaactgt ctgtacaggc ttgatattag actcattctt tccttgattt tcttcctttt 120

<210> 480

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 480

attatttgtg ccatctctca atgttgacgg acagcctatt tttgccaata tcacactgcc 60

aggtactgac gttttacttt ttaaaaagat aaggttgttg tggtaagtac aggatagacc 120

<210> 481

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 481

tacgaaccaa acctatttaa aactccacaa aggtgcccat cttataatca gctggcttca 60

actccaataa tattctgcga gcaagggctg actctgccgc tgtaccaatc tcctgttgca 120

<210> 482

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 482

tacgctttaa tttatttgtg aggggacgct cttgtattat ctgtggctca gtaactgctg 60

ctcctataat tagattttca gttacatggc ttaagttggg gaggcttgcc ttcttccgat 120

<210> 483

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 483

tacttccagc ccatctgtta tgttggctcc ttgctaagcc aggctgtttg cttttattac 60

agaattcagc cttttctaca ttcattctgt ctttagtgag taattgcctg ctgttctcat 120

<210> 484

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 484

tacttgctgc atatgtggtc acactttgtg gagacaggtt ccttgatcaa ctccagacta 60

gcagggtagg gggggagtgc aagtgcataa atgaggctca ataatttatt ttgcaattgc 120

<210> 485

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 485

tagaagcctt attcacttgc attcaggagg aatttgaaga acatgaaggt tgcattagtt 60

atatggtaca cattgttatt tctaatatga gaactgcgtc ttagagactt tgaatttaac 120

<210> 486

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 486

ccgtgccatt tacccttata aacagttcca aaagagcctg acccaatccg agtggacagc 60

atcacttcac tggcttctat ttcccaataa tagcttgaat ctctctgtcc acgaggcctc 120

<210> 487

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 487

taggattctc tgagcatggc agtttctgct tattccattc ttttctctca cacaggggat 60

cagcattcag atctaccttt ttttctgtgc tgggagtccg cctatcatta catgtttcct 120

<210> 488

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 488

taggattgac tgcttcttta agttcactgg tatttgaaca cttagttgca gaaccaggtg 60

catttgttaa cttcagctct gggtgcgtat cgctgtcatg tcttttactt gtctgttcat 120

<210> 489

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 489

ccattaattg actgacatta ccacccccaa ggtgccctat tacctcaatc atcctgctgt 60

ccacaggcag ggtggtgctg accatgtgga cattaggtgt ggatgtcgac ctctgcctct 120

<210> 490

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 490

taggcagata tgttactaca taattatgat aggctacgtt ttcagcagat tatcagatgt 60

cttctcctaa ttgtgagata tattatctgc gtcctttatc actttgtatg gcctgcagga 120

<210> 491

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 491

tattgctgcc tgtatgctgc tgcctggaga aagtatggtg tgctgcatta acaatcagag 60

ttcaatataa attgcgatgt cagataccac agcatcttta cattgatgtt tcttaccttt 120

<210> 492

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 492

tatactgcat gctgctgatc ccaagtggtc caccccaact tgcgactgta cttcagggcc 60

gtacactgct ctgctcattc ctggtacagg tgccaagctt ctggtaagtt aatgttgcct 120

<210> 493

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 493

tatcaaggga tgtcacaacc gtgtggaagt tgcgtattgt aagctattca tgctgcgtgc 60

aagattcagg taagtatgta aatgctttgt ttttatcagt tttattaact ttgctgctga 120

<210> 494

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 494

tatcttgcag tagtattcca acaatttata tgaatgagaa tcttctttta tgcataagat 60

tgcctagttt ttgccagttt ttttgcataa cctaagggat ttgctttgtt ttattttagt 120

<210> 495

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 495

tatgatatct gtaatagaat tgaatacata tttaactact tgctcaatat atttattaat 60

ttgtccagat ttctgctaac agtactcggc ctgctcgctg gtatacctgc cttggattct 120

<210> 496

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 496

tatgcctagt agactgagaa ggtatattgt ttactttacc tgctaacaag tgttggaagc 60

agggaagctc ttcatcctca ctagataagt tctcttctga ggactctaat ttcttggccc 120

<210> 497

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 497

tatgtgcttt tgctgtgcat tattgcaacg ttgagctgtt gccacctgaa tgctacatga 60

gagtagcatc accttcaaga aaggtacaat tcaacctgca cactgctcta agagtaatcc 120

<210> 498

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 498

tattaactgt ctgtacaggc ttgatattag actcattctt tccttgattt tcttcctttt 60

gttcacattc tgcagtgact tttggacttt gtttctttaa ggacccagag tgggcagaga 120

<210> 499

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 499

tattgggttt tcatacagct agcgggtgca aagtttgcat tgctgcggaa tctttggaca 60

aagtgtgcaa ccgcagagat gtgcaagagc aaggtactag tgtgctcacc agttttagcc 120

<210> 500

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 500

tatttcagaa tgcgacctat tagacacaga gaactgcaga aagtgcgatt ttcttacttc 60

agagaattct ttgccacgta tttctagcct acctgcatca gagaagccat ttgctgagca 120

<210> 501

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 501

tctgcaagtc tatattcaga ataagagaat caccttgcga gactttcaat gcaaggcaga 60

caggtcatat gactgatcca aacttttgca aagtgcctga agcctctgaa agtggactgg 120

<210> 502

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 502

tcccactatc taaggtaatt gttctctctt attttcctga cagtttagaa atcagtcccc 60

agaatgtgga tgttaatgtg caccccacaa agcatgaagt tcacttcctg cacgaggaga 120

<210> 503

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 503

tcaagtgcaa tcctttgcgg cttctgcaag cactccagat ggttgcatta gcgcagaatt 60

tatatctgtt ctccctctat aggtatggta tataatattc tgacctcagg tgatccaccg 120

<210> 504

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 504

tcaattcatt ttgtttctgc tgtgtcatgt aatctgctag tagatgtgct ttttgatgtc 60

tgactgctgc taaggcagag cattctagtg ataatataca atacacataa agcagaatct 120

<210> 505

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 505

tcacaggaga gaatattgtg tcctccctct ctgacagggc acccaatact tactgtgcca 60

agggtgaatg atgtgcgctc cttcaccaca gaagcaccac acagctgtac catccattcc 120

<210> 506

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 506

tcactattca cctacgtcta gactgcatgt atctgcaata cttcctcgtg ttgataagag 60

tgccccagag cactgtgtaa actcagtgct ggtgctgccc tgcagttgcg aattttgctt 120

<210> 507

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 507

tcagaagctc caccctataa ttctgaacct gcagaagaat ctgaacataa tgccaacaat 60

tacgaaccaa acctatttaa aactccacaa aggtgcccat cttataatca gctggcttca 120

<210> 508

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 508

tcaggacatc cattttatca agtttctgct acaagtgctg tgctgctgag acacttgatt 60

actacaggca gaccaaccaa agtctttgtt ccacctttta tgccttgctc acattttcac 120

<210> 509

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 509

tcagggctct gtgtgacact ccaggtgtgg atcctgcgct tatttctaga atttgggttt 60

ataatcacta tagatggatc atatggtgcc tggcagctat ggaatgtgcc tttcctaagg 120

<210> 510

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 510

tcatagtgca gacaggttac atacagcaga agaacgtgct cttttcacgg agatagagag 60

gtcagcgatt cactgcagag cacaggaaga atgacagagg agaggtcctt ccctcttgcg 120

<210> 511

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 511

tcatgctgaa agtgccctgc cacaacccat caggataaga gtgcgagaag cttccttcaa 60

tggaagtgga gcagacacgt catatttaag gcattcaggc caggcgcagt ggctcacccc 120

<210> 512

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 512

tcatttgttt ggaagaacca atcaagtgcg gatcctgggt gtttgtattt gcagtcaagt 60

cttccaattc actgcactgt gaagtgcaca agctagcaga acattttgtt tcctcactaa 120

<210> 513

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 513

tccaatcatg atgtgcgtct gaagtgcaat gatagattta tcgcttctgt gacagacagt 60

gtgcacacaa atctgcgaga agctgcaagt catggtaagt cctctgttta gttgaactac 120

<210> 514

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 514

tccagaatgt tgttaagtct tagtcattag ggagatacat atggatacac tcactgcttc 60

ttctggggtc aggccagaca ccaccatgga cattcttttg ttgacccttt ctgttgaagc 120

<210> 515

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 515

cgggagaggc cagatcaggc aactggagaa atcacccacc ttgaacttct tcctcttctc 60

tacctcctcc ttgaggcacg cctcatagtt tgcaatctca gcctccacac acttcagcag 120

<210> 516

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 516

acctgaatag gcaagtcgag gcaatggaaa agctcattaa cttaactgac attctcaaac 60

aggagaagaa ggatgaaaca caaaaggtgt gtgactctag tttgtgtttg agactctttt 120

<210> 517

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 517

tccccgcaga ttacccccag tggtatgtgg gagtttgttt catacaccaa agtttgtgaa 60

ggttgctatt ctacctggtt tagcagaatg acttagtaat tgagaatttg acaatagcgt 120

<210> 518

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 518

tccctctgaa aggaatggga gaagtttaat ttacacaacg atgaatgttg aattactgcg 60

ttctggtctc tgttaagaat ttgcaagacc aattgcgtta ggttaagaga tgcatgggta 120

<210> 519

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 519

tcttgctctc atttgtatga acatctgact ttggtgcaat cttcaagcaa tttagcagtt 60

tcaggacatc cattttatca agtttctgct acaagtgctg tgctgctgag acacttgatt 120

<210> 520

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 520

tctaagcatt tgctgcggcg acaattgctt attgacgctt aacctttcca gtttataaga 60

ctggaatata atttctgccc acacattagt acttatgttg cacaatgaga tgcgtgctta 120

<210> 521

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 521

tctcctgcca gttatactga gtatttggcg tccatcatca gatttatatt ctctgttaac 60

agaaggtgcg agatacagaa tttatcatct tgcaacttca tgctcttgca gttgctctgt 120

<210> 522

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 522

tctcccacac tatagggtgc agacagagtc ctaataagaa acactagtta catgtatgca 60

gaactgtcaa atgaccaaga tctgccattt tagctctttc gattacagaa agctgaccaa 120

<210> 523

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 523

tctctcttcc tctcttcttc cagatcttca gggggctaga aatctgttgc tatgggccct 60

tcaccaacat gcccacaggt aagagcctgg gagaacccca gagttccagc accagccttt 120

<210> 524

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 524

tctgctagtc ctgcagaggg ccactttcaa gagacattca actgcatgaa tgctactgtt 60

gaggtaaggt tacttttcag catcaccaca cattttggta gcagactatt ttgacagtcc 120

<210> 525

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 525

agtgcccgct ccttggggaa ggggttggcc acaggcatcc ggacatcccg aaactcctca 60

tcggagaaga ggaggctgct gacagggagg tggctgtaca tggaataaga ggctggcggt 120

<210> 526

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 526

tctgtatctt gctgcaacat ccactctgcc tcgaatctct ctgtgcgcag cagtaggagg 60

ccaagttccc tctgcgtgtt ctcattgcca ggtatgtgtt tgtctacaat actgatgcat 120

<210> 527

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 527

tctgttgttt caatgtttaa gatagtgcat cataatgata tgcctgtaag tgtgctgcat 60

aattgctgcc aactgatatt actgcataat attgtgctga ctactggcac ttttgttgat 120

<210> 528

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 528

tctttgcatt catctaacac atctataata acattctttt cgcagatttc cattctagga 60

cttgcccctt tcgtctattt gtcagacgaa tgttacaatt tactggcaat tgcgttttgg 120

<210> 529

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 529

tcttagtgca cacaactgca ccatatttac catcacgtgc actaacaaga cagcaagttc 60

gtgctttgca agatggtgca gagctttatg aagcagtgaa gaatgcagca gacccagctt 120

<210> 530

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 530

tcttcaatga taattgcttc tcctctgtgt tcttagacag acactcggta gcaacggtgc 60

tatgcctagt agactgagaa ggtatattgt ttactttacc tgctaacaag tgttggaagc 120

<210> 531

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 531

tcttcagtgc ataatcactc tatttgcgtt tctccatatc tctctcaatt tcaacaagac 60

tgccaacagt tggtattagg aacctgcgtg tcacttgttg agaacattca tgttttggga 120

<210> 532

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 532

tcttcctaag acgcagatgc gtgaatattt ttaaggcagt tctagaagaa tgtgcactct 60

tatgatatct gtaatagaat tgaatacata tttaactact tgctcaatat atttattaat 120

<210> 533

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 533

tctttagggg tgacccagtc tatttgcgaa agtgcaatgc tgaatgaggt aagtacttga 60

tgttactgcc taaccagaga tattcattca gtcatatagt ttgcaatgta tttgcttcct 120

<210> 534

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 534

tctttgactc acctgcaata agttgcctta ttaacggtat cttcagaaga atcagatcct 60

tgctgctttc ccccctgcaa attgctcaat tgcagttttc ttaatttgca gggtttgcaa 120

<210> 535

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 535

tttctttagg agatttattt tttggacttc aaagcaagct ggtattttca tacaaattct 60

tctaattgct gtgtgtccca ggcagggaga cggtttccag ggaggggccg gccctgtgtg 120

<210> 536

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 536

tgactgctgc taaggcagag cattctagtg ataatataca atacacataa agcagaatct 60

tacagtcaga aatgaagaag catctgtgcc tgtatttcct catgatacta ctgctgtaag 120

<210> 537

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 537

tgacattcag agtgaagtgc ttttacaaca taacctgcat atgtctggat tggagtgcgt 60

ttcttgcata tcaccttgtg atgttagttt ggtgccttca gatatatgta aatgtagtat 120

<210> 538

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 538

agttaataag atgctacact ttaattctac aactatttaa tcaaacagat tattgaatgc 60

caacaagata aactgccttc gggtagatgc ttttcaggat ctccacaact tgaaccttct 120

<210> 539

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 539

agagcgtgct tccttttgca gggctgagcc taatcctctg ccagctttca ttaccctcta 60

tccttccaaa tgaaaatgaa aaggttgtgc agctgaattc atccttttct ctgagatgct 120

<210> 540

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 540

tgagtcagac ttcattactt gaagctgcaa aatggcttag agaaggaata tttgatggtc 60

aaccagtgcg aattgctact gcagattatg taggtgctta tttgtatgaa aataattcaa 120

<210> 541

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 541

tgatacatgt ttacttttgc ttggcagact gcagagtgtg tgtttatttt gtgtagctgt 60

atacgtatgg cgtttcttgc cattgcataa tgcttaacag ctgcaatgca gagtcttttc 120

<210> 542

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 542

tgatcctcat tatcatggaa aatttgtgca ttgttaagga aagtggtgca ttgatggaag 60

gaagctgcta cagcagaaac tatatgactg aatgaatatc tctggttagt ttgtaacatc 120

<210> 543

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 543

tgcaattctg aggtgtttgc gggaggaggg gagtgctagt attatactta cagtgctagc 60

taactaccca ttttcctccc gcaattccta gtgcatattt cagtgtccgt tcacacacaa 120

<210> 544

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 544

tgcgaattaa gaagtgccaa aggcaacgcg tctttccaca gccaggcagt ctgtatcttg 60

ctgcaacatc cactctgcct cgaatctctc tgtgcgcagc agtaggaggc caagttccct 120

<210> 545

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 545

tgctcactgt acttggaatg ttctcatttc ccatttctct ttcaggtgac attgaatgtt 60

cctctgcgtt ttcctctagc agagcagact tacatttagt tttaactgct gacttgatgg 120

<210> 546

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 546

tgcttgtttc ccgactgtgg ttaacttcat gtcccaatgg atactttgcg ccttctgtgt 60

catttctatt atctttggaa caaccatgaa ttagtccctt ggggttttca aatgctgcac 120

<210> 547

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 547

aagtgtcact gacatcgatg tcctgtcttt ggcactttta caacaggtga aacgaatacc 60

attcagtttg cggcaaatct gtaacatatg taagaacgaa cgtttcttgt tcatttgtaa 120

<210> 548

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 548

tggatcaagc agatgatgtt tcctgtccac ttcttgcttc ttgtcttagt gtgcggtatg 60

atgaagctat tatatttgca tattttgctg tgccattttc ctacatatat ttgttctata 120

<210> 549

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 549

tggctgcact ataagataag gaatccagca attattatta aatactttgc tgccctgaga 60

cccttaccca attcaatgta gacagacgtc ttttgaggtt gtatccgctg ctttgtcctc 120

<210> 550

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 550

tggcgaccag aatcctgctc aggccttctt actttatttg ctggagattt ttctgtgttt 60

tctgctagtc ctgcagaggg ccactttcaa gagacattca actgcatgaa tgctactgtt 120

<210> 551

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 551

tggctgatgg tggatggctc ataccctcca atgatggtgc ggctggtgca gaagaatttt 60

ataggtactc tatgctgcaa gattgtgtgt taacttttat gtattccctc atccctcttt 120

<210> 552

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 552

tgtagaagtc ttttggcacg gtttctgtag cccatacttt ggatgataga aacttcatct 60

tttagatgtt caggagagtt attttccttt tttgctgcat tatagctgtt tgcatctgta 120

<210> 553

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 553

tgtcaattaa tgcagatttg gtttatgttc ttgcagagga gaactgcaat agtgttgcgc 60

agcatattgc aatgactcta ggtcaagatt ttgcatcgga catctccttg aatatagata 120

<210> 554

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 554

tgtcaattct ggcttctccc tgctcacact ttcttccatt gcattatacc cagcagtatc 60

agtagtatga gcagcagctg gactctgggc agattctgca actttcaatt ggggaacttt 120

<210> 555

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 555

tcaatgttct ctgatttcag gattaagcct atcgtatggc ccagtctccc cgatcataag 60

aagactctgg aacatctttg taagaaacca agaaaagtga gtgtttttgg tgcttaaaaa 120

<210> 556

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 556

tgtcttggtc aagttcttta gctacaccac ccacccttag ttctactgtg ctcataggta 60

ataatagcaa atgtgtattt acaagtgcga gcagatgagg ttgataattg tcatctctaa 120

<210> 557

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 557

tgtgacagac agtgtgcaca ctgctctgcg agaagctgca agtcatggta agtcctctgt 60

ttagttgaac tacaggtttt tttgttgttg ttgttttgat gcagagcaga tgaggtggag 120

<210> 558

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 558

tgtgattgat ggtactttaa ttttgtcact ttgtggcaga atgtttaggt ttattgcatt 60

cttctgtgaa aagaagctgt tcacagaatg attctgaaga accaactttg tccttaacta 120

<210> 559

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 559

aattattagg aaccaatgtt acttacttga gctgtccttc agctgtatct ggactatgtc 60

tgtagtgaaa atcagtatag ggtgctaaaa ttctctattt aaaaaaaaaa aggaagaaaa 120

<210> 560

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 560

tgtttaatta atatgcctta actgcagtaa tccatagtca agatcttaag cagcagattc 60

cttatgatct ttaactgttc tgggtcacaa atttgtctgt cactggttaa aactaaggtg 120

<210> 561

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 561

tggcagaatg tttaggttta ttgcattctt ctgtgtgcag aagctgttca cagaatgatt 60

ctgaagaacc aactttgtcc ttaactagct cttttgggac aattctgagg tgctgttcta 120

<210> 562

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 562

tggcagagtt atttaaggtg aagcagcatc tgggtgtgag agtgtgccaa gcgtctctga 60

agactgctca gggctatcct ctcagagtga cattttaacc actcaggtaa tgcgcgtgtg 120

<210> 563

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 563

tttgcggtgc tacttttgga aacattgcta tgtgggtttg caatttataa agcagctttt 60

ccacttattt tcttagaata ttgacatact ttgcaatgaa gcagtgcaca agcttatgca 120

<210> 564

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 564

cttcagtgaa tataagaatt atgactaagc caagaacttc cagtttttat tttttaaaca 60

tcatttaaca agaaaaaaca ttcaaccaaa ttaaaaagaa ctaggttgga ttaatttaca 120

<210> 565

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 565

ttaaggtgca caacgagaat tgctctgcaa tttgcctgcc gtgcattatg gcaggttgtt 60

acgaggcatt ggatgattca gaggatattc ttcataactc tctagataat gatgaatgtc 120

<210> 566

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 566

ccttgctgta cgtccatgcc ctgcgggacg cccctgagga ggtgcccagc ttccgcctgg 60

gccagcatct ctacggcacg taccgcacac ggctgcatga gaacaactgg atctgcatcc 120

<210> 567

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 567

ttaggactct gtcttttccc tatagtgtgg gagatcaaga attgttacaa atcacccctc 60

aaggaaccag ggatgtgctc agtttggatt ctgctgctgc gggtaatggc tgcgtttgcc 120

<210> 568

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 568

ttaggtattg tatgacaatt tgtgtgatga agcagagcct ttcagttaga tatttccgtt 60

gtttgctaat gtcctgatgg ttttccccct ttggtggtgg taagcagagc gcccgcagaa 120

<210> 569

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 569

ttagtgatat tgagaatatt agtgaggtgc cttctgcaga ggtacatcca ataagtttat 60

cttcaagtaa atgtcatgat tctgttgttt caatgtttaa gatagtgcat cataatgata 120

<210> 570

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 570

ttatagattt tgcatgctga aacttctcaa ccagaagtgc gggccttcac agtgtccttt 60

atgtaagaat gatataacca tgcggtatat aatttggtaa tgatgctagg ttggaagcaa 120

<210> 571

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 571

tttataaact tattggttat aggaagatgt tctgagctta ctggaaacct tccagttgga 60

cacaaggctg cttcatcacc tgtgtgggca ttccaaggta agaaggggag caggttctat 120

<210> 572

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 572

aaagataaaa ttatatatct aattatataa ttagataaaa agaatcaaac caagctgttc 60

ccctgctccc aaaacataat tcggaattta acaagaaagc ctagttctgg ttcccaaaac 120

<210> 573

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 573

ttattacccc agaagctgat tctctgtcat gcctgcagga aggacagtgt gtgcatgatc 60

ctgcaagcaa tgcagtttca gatattgcag aagaggtctt ggctgcagca tgtcacccag 120

<210> 574

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 574

ttatttgttc agggctctgt gtgacactcc aggtgtggat cctgcgctta tttctagaat 60

ttgggtttat aatcactata gatggatcat atggtgcctg gcagctatgg aatgtgcctt 120

<210> 575

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 575

ttagcagagt atattttcag ctgcttgtga attttctgag acggatgtaa ctgctactga 60

acatcatcaa cccagtaata atgatttgaa caccactgag aagcgtgcag ctgagaggca 120

<210> 576

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 576

ttcaatataa attgcgatgt cagataccac agcatcttta cattgatgtt tcttaccttt 60

ccactcctgg ttctttattt ttactggtag aactatctgc agacacctca aacttgtcag 120

<210> 577

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 577

ttcagcatga ttttgaagtc agaggagatg tggtcaatgg aagtgcccac caaggtccaa 60

agcgagcaag agaatcccag gacagtgcgg ttgcgctccc tccctcaagt tgactgcaat 120

<210> 578

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 578

ttcagccacc aaggagttgt ggcacctgct acgtgccacc cattgcgtgc tgcgaactga 60

attctcctca gatgactcca ttttgctgct tcaatgtgct ttctcttttg gtgcgtaatt 120

<210> 579

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 579

tagacccaac acaacttcct tatgatcaca aatgggagtt tcccagaaac aggctgagtt 60

ttggtcagta tgaaacaggg gctttccatg tcaccttttt gggtacacat aacagtgact 120

<210> 580

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 580

tgagacttcg atgctttccc caatacttgt cgtctgattc tccaggtttc ctgtgatcgt 60

gggtgccaca cgctctagac acacaaaaag aaaatcacag aacatggaat tataactttt 120

<210> 581

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 581

tttgggaggt tcatcggtca cagaatggtt gacacaggag cctgacactt cgagcaattg 60

ggaagaatca gctccagtga tggtgtcagg gaagacagcc aagtgtcgta ccacagaagg 120

<210> 582

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 582

agcatgttga aagcatactt tctgcatttg atattcttca gtacattctc tatgcggcat 60

ccttctctgg tgaaagggga aaaagtacaa cttcatgaaa cacagaataa ataaatatgc 120

<210> 583

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 583

ttcctgcgaa tgctgcttta taatccagag tatatacatt ctcactgaat tattgtactg 60

tttcaggaag gaatgttccc aatagtagac attgcagtct tcgcacagtg tgcacttgca 120

<210> 584

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 584

ttcctgaccc tagacctttt cctctgccct tatcatcgct tttcagtgat ggaggtgctg 60

ttggttgtgt tgatgtaatt attctgcgag cataccctat acaggtatga tgtattcttg 120

<210> 585

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 585

ttctacagag tgaacccgaa aatccttcct tggttgcacc atttgttttc ttcttcttct 60

tcttcttctt ttcgcagatt tttcgcagat gcagatgaga tggagtcttg ctctgtgttt 120

<210> 586

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 586

ttctcattcc attttgcgca gtattaactt cacagtgcag tagtgaatac cctataagcc 60

agaatccaga aggcctttct gctgacaagt ttgaggtgtc tgcagatagt tctaccttgc 120

<210> 587

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 587

ttctcctgcc agttatactg agtatttggc gtccatcatc agatttatat tctctgttaa 60

cagaaggtgc gagatacaga atttatcatc ttgcaacttc tgcatcttgc agttgctctg 120

<210> 588

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 588

ttctgctgtg cctgactggc atttggttgt acgcagattt ctttatctct tcactgctag 60

aacaactatc aatttgcaat tcagtacaat taggtgggct tagatttcta ctgactacta 120

<210> 589

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 589

ttctggggtc aggccagaca ccaccatgga cattcttttg ttgacccttt ctgttgaagc 60

tgtcaattct ggcttctccc tgctcacact ttcttccatt gcattatacc cagcagtatc 120

<210> 590

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 590

ttcttgcagt tgcgcaggca atatctggaa cttctccagt ggcttcttca tttcagggta 60

tctgcaagtc tatattcaga ataagagaat caccttgcga gactttcaat gcaaggcaga 120

<210> 591

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 591

ttgtgccctt gaatgtattc tgctgctact gagcatcaag ttcactttct tccatttcta 60

tgcttgtttc ccgactgtgg ttaacttcat gtcccaatgg atactttgcg ccttctgtgt 120

<210> 592

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 592

tgatggtgtt ctgtcttacc agaggctgtg gccctgagaa agatcacgtc tacctgcagc 60

tgcaccacct acctccagag cagctggcca cgcgcctgcc tggcatttca gagacagcca 120

<210> 593

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 593

ttgagtgcca cactcagcaa gtgattatca accttttaag gacacttgca taagtgcaga 60

catgttgcca aattgcaata agatgcagca acagtagtgc acctctataa tcaatacatc 120

<210> 594

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 594

ttgagacttc tgatacattt tttcagactg caagtgggaa tgctattagt gtcgcctgcg 60

agtcatttaa ttgcattgta aatttctttg atcagtgccc agaagaattg cataactttt 120

<210> 595

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 595

ttgagatcac agctgcccca aagtgttgcg tgctgcagaa ttctctcaat aatgattgca 60

accttgtttc tattgagact gtggtgccac ctaagctctt aagtgataat ttatgtatcc 120

<210> 596

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 596

ttgcagaatg tgtgcagcta gcagaccaat catgatgtgc gtctgaagaa tgctgataga 60

tttatcgctt ctgtgacaga cagtgtgcac actgctctgc gagaagctgc aagtcatggt 120

<210> 597

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 597

ttgctgacat tcagagtgaa gtgcttttac aacataacca tgctatgtct ggattggaga 60

aagtttctaa aatatcacct tgtgatgtta gtttggtgcc ttcagatata tgttgctgta 120

<210> 598

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 598

ttgctggaga cagagaacac aagcagagat tagtgtcaat tcattctcct ggactaggct 60

ctaatcaatc gactccaggg tcctggttgt atgagttctt aggattaatg aggtagaagc 120

<210> 599

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 599

ttgctttagg tgctactaag gaacttcatg tgccagactt gacttgtgta aacgaaccca 60

ttttcaagaa ctctaccatg gttttatatg gagacacagg tgattgccaa gcaacccaag 120

<210> 600

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 600

ttgcttttat tattagcata tacctgcata aataggcata ttagagtttc ctttcttgca 60

tctttgcatt catctaacac atctataata acattctttt cgcagatttc cattctagga 120

<210> 601

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 601

ttggaggtgc acagactgca gctgcacatt gatggacatg gctctgatga tagttgcaat 60

aagattaatg acaatgagat tcatcagttt aactgcaaca actccaatca agcagtaggc 120

<210> 602

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 602

ttggcttgtt actcttcttg gctccagttg caggttcttt accttccatg agttgtaggt 60

ttctgctgtg cctgactggc atttggttgt acgcagattt ctttatctct tcactgctag 120

<210> 603

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 603

ttggttgtgt tgatgtaatt attctgcgag cataccctat acaggtatga tgtattcttg 60

tgccttacca tatatttctt tcttttgata caattaattt gtttgtttgt ttgagatggc 120

<210> 604

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 604

ttgtccagat ttctgctaac agtactcggc ctgctcgctg gtatacctgc cttggattct 60

ttcctgaccc tagacctttt cctctgccct tatcatcgct tttcagtgat ggaggtgctg 120

<210> 605

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 605

aacttatgcc acttgttgta gtgtctgtat tgaaactttg gctacgtatc ttcatatgtg 60

agctcgttga actttctact actaacctct ctcggcttgt attttctctg tgattctctg 120

<210> 606

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 606

ttgtttccta ggcacaataa aagatcgaag attgtttatg catcatgttt ctttagagcc 60

gattacctgt gtaccctttc ggtaagacat gttttgcttt ttcttgcttc taatacagta 120

<210> 607

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 607

ttttgccagt ggaattctag agtcacactt ccttgcatat gcagcagagt tttcactttt 60

agatatgata cggtgcttga tagaagcaga agatcggcta ttgctgcgat aatggtgcgg 120

<210> 608

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 608

ttttgcgcat tacattacgt aatcatatac ggcagtatgg ttaaggtttc tgtgtagtct 60

gtgacttcca tgtctgcatg ttgcacaagc cagttgtcag tgacagttgc catcccacac 120

<210> 609

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 609

tttaacacat tagtgcaaca tatatatata tcgcagatgc aggtttataa aatgacaact 60

tcattttatc agcagagcat tgcgttgctt taagatttgg aaggttttag aataatacaa 120

<210> 610

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 610

tttaattctc agtatttctt agattgcttc aggcagaatt ctcagttatt cagtgacttg 60

ttttgccagt ggaattctag agtcacactt ccttgcatat gcagcagagt tttcactttt 120

<210> 611

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 611

tttagatgtt caggagagtt attttccttt tttgctgcat tatagctgtt tgcatctgta 60

tgctacaagg gtgcacatta tgtttgcagt tagagtgcaa tgtatgaatt ataatctgcg 120

<210> 612

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 612

tttaggagaa ccctcaatca tgcgtgcctt atttgctgaa tttgacagga taatagtgca 60

tcaagtgcaa tcctttgcgg cttctgcaag cactccagat ggttgcatta gcgcagaatt 120

<210> 613

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 613

tttagtagcc aggacagtag aaggactgaa gagtgagagg agctcccagg gcctggtgcg 60

gccactttgt aagctcattc ttggggtcct gtggctctgt acctgtggct ggctgcagtc 120

<210> 614

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 614

tttattgctt tttctgatga atggttttat aggaacgcta tgttatttgc taatttctac 60

gcagacctac tgtggttgct tccaacctag catcattacc tgcttatata ccttttggtt 120

<210> 615

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 615

ggctgccgtc cctctcctcc gtcagttttg ttgcttcttt atccttacat tgcacacagc 60

ccattatcta aattcctgcc aaagacaaaa aagggggcac gtaagctggg atgctcccta 120

<210> 616

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 616

tttctgcgcg ccagtcattt gctccgtttt ctgctccagg tgctgcagaa gaggaatgtg 60

caacattctc tgcccactct gggtccttaa agtgcctgcg tcctgcagtc acttttgaat 120

<210> 617

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 617

tttcaggaag gaatgttccc aatagtagac attgcagtct tcgcacagtg tgcacttgca 60

tggatcaagc agatgatgtt tcctgtccac ttcttgcttc ttgtcttagt gtgcggtatg 120

<210> 618

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 618

tttcggtaag acatgtttaa agcagactaa attctaatac agtatgagaa aagtctcgtt 60

tttattgctg aacatttcta tgcataatga cactaacgtt aagaagttaa cacttcccgt 120

<210> 619

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 619

tttctttata atttatagat tttgcatgct gtgccttctc aaccagaaga aagggccttc 60

acagtgtcct ttatgtaaga atgatataac ctgcaggtat ataatttggt aatgatgcta 120

<210> 620

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 620

aggtacagta ggataagcca ctctgtccct tcctgggcaa agaagaaacg gaggggatgg 60

aattcttcct tagacttact tttgtaaaaa tgtccccacg gtacttactc cccactgatg 120

<210> 621

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 621

attaacaaca gacagcaata acttcgtttt agaaacattc aagcaatagc tttatagctt 60

caacatatgg tacgttttaa ccttgaaagt tttgcaatga tgaaagcagt atttgtacaa 120

<210> 622

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 622

tttggtaact cagactcagc atcagctgca accttaggtg tttgccgtta ggtgttgcaa 60

tgcaattctg aggtgtttgc gggaggaggg gagtgctagt attatactta cagtgctagc 120

<210> 623

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 623

tttgtctgct tcaagaattg gtgcaagaag aggagagccc cttatcttag tgggtaagtg 60

ttcagcagaa cctttcgtgt tgccaatcac tagcagatgc gtgtttattc agtagacttg 120

<210> 624

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 624

ttttagccat caatgggcaa agacccttgc gtacagagag gcctgttgcg accttgaatt 60

agcatgtgag accattgaga tcacagctgc ccctgcgtgt tgcgtgctgc agaattggtc 120

<210> 625

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 625

ttttcaagaa ctctaccatg gttttatatg gagacacagg tgattgccaa gcaacccaag 60

tgtcaattaa tgcagatttg gtttatgttc ttgcagagga gaactgcaat agtgttgcgc 120

<210> 626

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 626

ttttcaggtc atatgactga tcctgccttt tgctgcgtgc ctgaagcctc tgtgcgtgga 60

ctggtgctac atactgtttg ctcacagaag gaggactcct tatgtcctgc tttaaccgta 120

<210> 627

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 627

ttttcatata atgtggttgc ttcatctgct ttctctggat ttagtacagc aagtggtgcg 60

caagtttcca ttttagtgcg ttccttacac tgcgttaagg gagtgttaga ggaatttttg 120

<210> 628

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 628

ttttctcccc attgcagcac aactaaggaa cgtcaagaga tacagaatcc tgcttttacc 60

gcacctggtc aagaatttct gtcttgctct catttgtatg aacatctgac tttggtgccc 120

<210> 629

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 629

gggctggagg gggtgggtct agggaggggc aagggcaggg cttggctacc aacctgaaac 60

attgacggag aagtaggtgg tgtcactgcc cgaggggctg ctggttacgc aagcatagag 120

<210> 630

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 630

gcagacctac tgtggttgct tccaacctag catcattacc tgcttatata ccttttggtt 60

atatcattct tacattgcgg acactgtgaa ggccctttct tctggttgag aagtttcagc 120

<210> 631

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 631

gcagagcaga gttgctagta catatagttt tatagatgac gattccttct gtggcagatt 60

ctgcgcagaa tgctcttcat atcttatatt taatcttagg catcatctgt atacatgatt 120

<210> 632

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 632

gtgtaatgta cgctagttac cacttgtact tgcatgcctt aaggctagag tacaaattgt 60

atttacataa ttacacactt tgtctttgac ttcgcagact tcgcagaacc atctttgctc 120

<210> 633

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 633

atttacataa ttacacactt tgtctttgac ttcgcagact tcgcagaacc atctttgctc 60

atcttttctt tatgttttcg aatttctcga actaatgtat agaaggcatc atcaacaccc 120

<210> 634

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 634

atcttttctt tatgttttcg aatttctcga actaatgtat agaaggcatc atcaacaccc 60

tgaaatacat aaaatgcatt aaaatgtgaa tatatacgat ggcttcatgt gtacaggtaa 120

<210> 635

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 635

tgaaatacat aaaatgcatt aaaatgtgaa tatatacgat ggcttcatgt gtacaggtaa 60

caaatttcat taatggaaaa aatattaaga aaggattctt tatgtttctc ttcaggcaac 120

<210> 636

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 636

ttttaatact tcatgctaga atactacacc tatgctgctc taatgcggtt gccaccttgt 60

tacctttaaa agacatctgc tttctgccaa aattaatgtg ctgaacttaa acttaccaga 120

<210> 637

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 637

tacctttaaa agacatctgc tttctgccaa aattaatgtg ctgaacttaa acttaccaga 60

ttacattata atgcgcaaga taattttcac acgcacagga gtcttttctt ctttgctgat 120

<210> 638

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 638

ttacattata atgcgcaaga taattttcac acgcacagga gtcttttctt ctttgctgat 60

gcagatcaat ctgtattgtc ggatctccct caccaatgta taaaagcaat cctccactct 120

<210> 639

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 639

gcagatcaat ctgtattgtc ggatctccct caccaatgta taaaagcaat cctccactct 60

ctgcattgta aaacacaact tctttaatgc ctgttgcatt ggtaagtgca atttactggg 120

<210> 640

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 640

ctgcattgta aaacacaact tctttaatgc ctgttgcatt ggtaagtgca atttactggg 60

aagcacatgt gcaagatgct tgagattatg gcattgagat gcaggcaaga ttaaacagac 120

<210> 641

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 641

acgctagcat ttactaaata ttgttttatt tccttgcata gcataattga gaggctagct 60

gatatattaa atgacataac tgctatgatt ttgcagaaaa cagatctgta tttatttcag 120

<210> 642

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 642

gatatattaa atgacataac tgctatgatt ttgcagaaaa cagatctgta tttatttcag 60

tgttacttac ctgtcttgtc tttgctgatg tttcaataaa aggaattcca taacttcttg 120

<210> 643

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 643

tgttacttac ctgtcttgtc tttgctgatg tttcaataaa aggaattcca taacttcttg 60

ctatgccctg gcactgtttt gtgtctactg ttctagaagg caaatcacat ttatttccta 120

<210> 644

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 644

ctatgccctg gcactgtttt gtgtctactg ttctagaagg caaatcacat ttatttccta 60

ctaggaccat aggtacatct tcagtgccct taactctttt aatttgttct ctgggaaaga 120

<210> 645

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 645

ctaggaccat aggtacatct tcagtgccct taactctttt aatttgttct ctgggaaaga 60

gctagatgct atgcaactgc catttgcaac acaaatatct ttcaaaacct gtccacaact 120

<210> 646

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 646

gctagatgct atgcaactgc catttgcaac acaaatatct ttcaaaacct gtccacaact 60

tttgtcataa aatttggctg aaagaaaaca atgtaattcc ttgcttccac tacaccaaat 120

<210> 647

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 647

tatgcatggc attgcaaaag actcgctaga tgctagctat aattactcct taatgtcgca 60

ttattatatt caatttaaac ccacctataa tggtgaatat cttcaaatga ttttgcatta 120

<210> 648

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 648

gcttattata ttcaatttaa acccacctat aatggtgaat atcttcaaat gattttgcat 60

tatttatggc aaatacacaa agaagcacct cccctgccct catgtactgg tccctcattg 120

<210> 649

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 649

attatttatg gcaaatacac aaagaagcac ctcccctgcc ctcatgtact ggtccctcat 60

tgcactgtac tcctcttgac ctgctgtgtc gagaatatcc aagagacagg tttctccatc 120

<210> 650

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 650

attgcactgt actcctcttg acctgctgtg tcgagaatat ccaagagaca ggtttctcca 60

tcaattacta cttgcttcct gtaggaatcc tgagaaggga gaaacactgc ctggattatt 120

<210> 651

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 651

catcaattac tacttgcttc ctgtaggaat cctgagaagg gagaaacaca gtctggatta 60

ttactgcgca ccttttactt cgctagaggt gttatataca actcaacaac gctagattca 120

<210> 652

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 652

cagataactt aactttcgca ataattatct tgtaatatgc actcatgaaa atggtcagag 60

aaacctttat ctgtatcaaa gaatggtcct gcacctgcaa tatgcatatt aaaacaagat 120

<210> 653

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 653

aaacctttat ctgtatcaaa gaatggtcct gcacctgcaa tatgcatatt aaaacaagat 60

ttacctctat tgttggatca tattcgtcca caaaatgatt ctgaattgca tgtatcgtca 120

<210> 654

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 654

ttacctctat tgttggatca tattcgtcca caaaatgatt ctgaattgca tgtatcgtca 60

aggcactctt gcctacgcca ccgcatccaa ctaccacaag tttatattca gtcattttca 120

<210> 655

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 655

aggcactctt gcctacgcca ccgcatccaa ctaccacaag tttatattca gtcattttca 60

gcaggcctta taatgctagt aatgaaaatg tgactatatt agaacatgtc acacataagg 120

<210> 656

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 656

gcaggcctta taatgctagt aatgaaaatg tgactatatt agaacatgtc acacataagg 60

ttaatacact atcaaatact ccacctgcac cttttaatac aaactcacct ttatatgaaa 120

<210> 657

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 657

tgcaacattt taaatttatc aaaaggattg gcagaatttt tattttaaag cattattaaa 60

tatggatcag acttgaaaag tgtttatgca atgttaattt aacctgcgtt aagagaacta 120

<210> 658

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 658

gccaaaccta gagattgtaa aacgcagaca cttcattgtt tgctagaaaa attaatgtct 60

tggcacacca ccaccccaaa atctcaactt ttgtgctaat atttaaatgc agcaagaaaa 120

<210> 659

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 659

aaagtgcttg ttttcttaag aaacaaagca aatgctcttg atttgtcgca aggaccacca 60

cagtgcgaga ttgtatcttg ttggcatatc caaactgccc ttgcccctcc ccattttgac 120

<210> 660

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 660

taaccaatgc atgacaacac tggatgaccg tggggacaca gtccatgctg tgaaactctc 60

tatgaagcat caaaggttca cacagggcct ggccttgcaa ccttggtctc ttcaacacct 120

<210> 661

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 661

aatagcatat aactggccca aataatcttt taatgtcaca gcaagaatta aaactatctt 60

caaagactca tgctgaagaa aagatttaaa gttatactat gaaaggcaag tctgacacag 120

<210> 662

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 662

ggagactaca tttaattcct atgagaattt tttatacttg ttaaaatctt ttcaattatt 60

atgctagttt tgcgcaatgt aaatatgcac ccaaaatggt tgctataata atccccattt 120

<210> 663

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 663

ctcacaaaca tatattctca tgactacttg catggaccag cccttccacc actccagaaa 60

cacacactaa ttggtgttat gttttgcaag cactggggat accaccatca cagaatttgc 120

<210> 664

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 664

cgcagaatag gctagatata atattttggg gagtgcgacc atgactaata gctgcggaaa 60

ggagacaaaa cctttgtgaa ctgcgtaact ttacattcat cagggatgac aaactatagg 120

<210> 665

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 665

acatgatgcc tagaagaatc atcatcagga gcaccataaa tttgtgttcc ctcaatgttt 60

ctgcgctagc caattagaag gtctcaactg aaatttgcaa ttaatccatt tatgtgacta 120

<210> 666

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 666

gataaaacac agaataggga tgattcaaaa gcttcattaa tttgtttcac accaacattc 60

acaattggta aggctagtaa gatgcaatca actgcatgca ccaaagcacc caagacagaa 120

<210> 667

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 667

atcttaggta ttctgcttct ttttcacagg cattgcttgc tcgctagcca aaactctggg 60

aatactggca cttagaggaa gctagaactt ccactgtcat tttaaaataa gcatttaagg 120

<210> 668

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 668

gatccaacat acagggtgga cagtgtctgg tgagatagca ggggctggac ggaccacgtg 60

accttgaagc tctcccactt ctaagagaaa aacctatgaa tgtcagatct ccttgtccaa 120

<210> 669

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 669

tttggtctct ggtttgtgaa ggacgctatg ccgactggtc ctccacggtc ttagggtacc 60

tttggtctct aagtgagtgt cggaccgacg tcaggcgcca gcgtggttca tcgttatctt 120

<210> 670

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 670

tttcttgatt gttcttcttt ctcttgaatg gcaagagaag aaacactttc tctaacccac 60

ggccaggaag gaaatgggga gagagctact tcttagttca acctggttgc cacataaagg 120

<210> 671

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 671

cgttttcaga taggttacct cgtatagacc acgtccaggg cgagtacggg cttctaaggg 60

caacgcctgt tcgtggtacg cgtatatgac tatcccacaa gggaagtgac gtacgctgaa 120

<210> 672

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 672

ctgcccatca ctgaccgtct gtggcaggca ctgccagtgg ccgtggccca gggtcttggt 60

ggctcggcct catggggggc ttgctccagg ccttgggtga tgctcctgtg ctccctgaca 120

<210> 673

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 673

ttttcgctgt tgagagacca ggagaggagg aagtatgtca gggtccttgg cgctcacagg 60

cactttctct tcctcttcca caagtggacc tatatcttac gcgaaacggg tgttgtatac 120

<210> 674

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 674

cactttctct tcctcttcca caagtggacc tatatcttac gcgaaacggg tgttgtatac 60

taccgggtcc tcgcgtaggg gaatattata aaactttgaa tcagagacaa aaatagttgg 120

<210> 675

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 675

aaatatatat ttcacttatt tgtactaaaa tcttgtactc tgactgcgtt gaccttattc 60

tatattcggt tattcgctac tttaagactg tttctataag agtaatagtt gaccaaaggc 120

<210> 676

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 676

tatattcggt tattcgctac tttaagactg tttctataag agtaatagtt gaccaaaggg 60

agaaatagtt ttacctgggt cgagttatca tacctctcca aatagtagcg aaagttggcg 120

<210> 677

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 677

agaaatagtt ttacctgggt cgagttatca tacctctcca aatagtagcg aaagttggcg 60

ctgtcttcag cgtgtagttg ccacgactga gtctattacc ggttactaaa agaagaagcc 120

<210> 678

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 678

ctgtcttcag cgtgtagttg ccacgactga gtctattacc ggttactaaa agaagaacga 60

ctatatataa ataaaggaga acgacataga tgcgtagtta tatttcttcc acgcccaggg 120

<210> 679

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 679

ctcttccttt tttatctggg ccacctcttg gtgtggtgca gggatcctga tgtgggaggt 60

gttcagcctg gggaagcagc cctatgactt gtatgacaac tcccaggtgg ttctgaaggt 120

<210> 680

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 680

tccgagtcac tatccgtact tgggcgtata taaagggagg cgacgctact cgcccttcta 60

cttaaagaag ctatagtgcg tctggtatat ttttgaaaag cgtacgtcgt tagtaactag 120

<210> 681

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 681

gccgtcccgg gagacttaca gcgcgagggg ccgctgggtc acatgggtcc cggggggtcc 60

cagagggtcc cggagctgga gctagagcca gagcggctgc cctgtgtcaa gggagagggt 120

<210> 682

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 682

cagaagtgtt cctaaaagag tctaacacag cgccaggcga gttcttgggt gggtcctacc 60

gcgctccact ggtgacaaac tccagaactt cctggttcgt tttcgtgggg ttagcgtata 120

<210> 683

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 683

gcgctccact ggtgacaaac tccagaactt cctggttcgt tttcgtgggg ttagcgtata 60

taccaagaga aaagtattcc ctaacgacga ctccaaagga cctggcgtag ggacagaggg 120

<210> 684

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 684

gggtgttatg tatcttctct tttccctccc tactaacaca cggcgtcccg cgttagagta 60

tagagtcctt tgcgccagga cgaccacctt tagcgtcgag ggtaacctgg aggtagtagg 120

<210> 685

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 685

tagagtcctt tgcgccagga cgaccacctt tagcgtcgag ggtaacctgg aggtagtagg 60

ctgacttacc tagtgtctgt tttagaagtg atatatcctt cctagaagcg ctcttcacgc 120

<210> 686

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 686

ctgacttacc tagtgtctgt tttagaagtg atatatcctt cctagaagcg ctcttcacgc 60

taccacttaa ctgcgacgta gcgacacgct ccctttctta agtacgtccg cctgtgggga 120

<210> 687

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 687

taccacttaa ctgcgacgta gcgacacgct ccctttctta agtacgtccg cctgtgggga 60

aggagaggaa aaccaaacta ggtactggag tagcgtataa cgtactcgcc tcgtgggaac 120

<210> 688

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 688

aggagaggaa aaccaaacta ggtactggag tagcgtataa cgtactcgcc tcgtgggaaa 60

gttgagaaag tgcgaacata taagtctacc ctataaaggt ctgaatataa cctagagtcc 120

<210> 689

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 689

gaacttagtg aatatttagg tagaaagttg acagggtacc aggagtagta gtaagggaca 60

acgacgcaca cccctatctt gagggcgtga ggtggaagag acagcgccgg aggggtgagg 120

<210> 690

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 690

acgacgcaca cccctatctt gagggcgtga ggtggaagag acagcgccgg aggggtgagg 60

cagtctttac tcacctgtag tagtctcggg cctacccgaa gtctccatac ttgcgcactc 120

<210> 691

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 691

cagtctttac tcacctgtag tagtctcggg cctacccgaa gtctccatac ttgcgcactc 60

ttccaggcgc tggacaggtc aagagcgagt ttctgcgacg atagtctctg ggaagaaagg 120

<210> 692

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 692

ttccaggcgc tggacaggtc aagagcgagt ttctgcgacg atagtctctg ggaagaaagg 60

aatacgtatt cctatattta tccctaggaa gtagagtgta caacgcgcta cactaggtat 120

<210> 693

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 693

aatacgtatt cctatattta tccctaggaa gtagagtgta caacgcgcta cactaggtat 60

tttactccaa cgtgaagttt aataagttcc ttcccttccc ttatattcct ttagttaagt 120

<210> 694

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 694

tactaccaaa tgcgtctgga gggagaccta gttatctcgt ctgatacacg aatagtgacg 60

ccttgagtac tcgggggaag cacacagtac acggacagga tgacaggaag acgacagtca 120

<210> 695

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 695

ccttgagtac tcgggggaag cacacagtac acggacagga tgacaggaag acgacagtca 60

ctttgactca ccggtggtag aagtggtttt cctccaataa ctgacacgca cagcgatagt 120

<210> 696

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 696

ctttgactca ccggtggtag aagtggtttt cctccaataa ctgacacgca cagcgatagt 60

cccgacgcac gtcgagaagg tccacgtagg ccagggagga ggcgtgcgtc tgtggggaga 120

<210> 697

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 697

cccgacgcac gtcgagaagg tccacgtagg ccagggagga ggcgtgcgtc tgtggggaga 60

cagaacgggg ccactgacga ggacgttgtc agtgagagga gggaatactg aatacgtgcg 120

<210> 698

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 698

cagaacgggg ccactgacga ggacgttgtc agtgagagga gggaatactg aatacgtgcg 60

ttccagtcgt cacaaggagg cagaccgtga actacgacgt acaccagggg cctcgcgcct 120

<210> 699

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 699

ttgacaccct gggttcctac gaggaacttg ctacccagcg tcgccactct tcgtccttcc 60

taccttcgtc ctgtccttgg cacaacaact cgacgaaaga ctggttctca ctcaccggcg 120

<210> 700

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 700

taccttcgtc ctgtccttgg cacaacaact cgacgaaaga ctggttctca ctcaccggcg 60

gaggcggggt ctctcggagg aaggacttga ggtctgtatg ccgctagacg tccacgagga 120

<210> 701

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 701

gaggcggggt ctctcggagg aaggacttga ggtctgtatg ccgctagacg tccacgagga 60

tgaaccgggg cagggtatcg agcgtcaccc catacgacgg aacatagttc tggtggttga 120

<210> 702

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 702

tgaaccgggg cagggtatcg agcgtcaccc catacgacgg aacatagttc tggtggttga 60

tattcgtcga gacgagagag ggtagtaacc aaatataact gacgtgagtc tggcgaatac 120

<210> 703

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 703

tattcgtcga gacgagagag ggtagtaacc aaatataact gacgtgagtc tggcgaatac 60

ttaaactggg aggaacagga tacaaagtta ctatttcacg acgtacatag ttaaaagcga 120

<210> 704

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 704

aaggggacta cgtagggaca acacgtattc ccttggagta tacgtactgt tagaaacctc 60

tccaggttct tttcacgcag aggggagttg gggtgagggt ggactggtgt gcgtttacct 120

<210> 705

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 705

tccaggttct tttcacgcag aggggagttg gggtgagggt ggactggtgt gcgtttacct 60

gtagtacagg cgttcctaga ggaataccag ttcgtcctgt tcagacgaca cttcagcgag 120

<210> 706

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 706

gtagtacagg cgttcctaga ggaataccag ttcgtcctgt tcagacgaca cttcagcgag 60

cgtctggcga gagaagggga gggtggggag gaggaggagg ctgtgacgtg agaactcgag 120

<210> 707

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 707

tgttcagacg acacttcagg cacggtctgg cgagagaagg ggagggtggg gaggaggagg 60

agcgtgtgag ctgagaactg cacgctacag agtcccgaag ccaaggcgag cgtcaagagt 120

<210> 708

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 708

cgtctggcga gagaagggga gggtggggag gaggaggagg ctgtgacgtg agaactcgag 60

cctacagagt cccgaacgca aggcgagcgt caagagtgag ccacttctta ccttcacacg 120

<210> 709

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 709

agcgtgtgag ctgagaactg cacgctacag agtcccgaag ccaaggcgag cgtcaagagt 60

gacgcacttc ttaccttcac acgcacttcg tacacgcttg ggtcgttggg ctatccggac 120

<210> 710

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 710

gacgcacttc ttaccttcac acgcacttcg tacacgcttg ggtcgttggg ctatccggac 60

acctgcgctt ctaacacctc cccaaagcgg cctagcgcca gacccctgtg caaaggagaa 120

<210> 711

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 711

acctgcgctt ctaacacctc cccaaagcgg cctagcgcca gacccctgtg caaaggagaa 60

gacaagagga gacagagtca aacagcgcac ataatagagg cacgttcacg tcctgacgct 120

<210> 712

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 712

gacaagagga gacagagtca aacagcgcac ataatagagg cacgttcacg tcctgacgct 60

ggcggtcaca tttagtggac aaacacgaga gcgtcacgta actaacacac tcaggagtaa 120

<210> 713

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 713

tcgcctaagg gaggcgtctg ccgcgctttt gtgcgtagag gagtctcggg tcgtgtgtaa 60

actatcacgc cctacactcg acccctctcc tcccaggacg cgacgaggcg cgtcaccgaa 120

<210> 714

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 714

actatcacgc cctacactcg acccctctcc tcccaggacg cgacgaggcg cgtcaccgaa 60

tgagggtgta gacggacccg gcgacctcct tcaggtcact gtaggaggag gtcttcgcag 120

<210> 715

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 715

tgagggtgta gacggacccg gcgacctcct tcaggtcact gtaggaggag gtcttcgcag 60

caaacgagta gttggggttg tagtcggtca tgtaggtcga ggtcgggacg ttcgtcacgt 120

<210> 716

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 716

caaacgagta gttggggttg tagtcggtca tgtaggtcga ggtcgggacg ttcgtcacgt 60

tgtactcagg cgtctcgacg tcctactcga tgcgttcgag ctcctggtcg ttccgcgggt 120

<210> 717

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 717

ggtcgggacg ttcgtcacgt tgtactcagg cgtctcgacg tcctactcga tgcgttcgag 60

ctcctggtcg ttccgcgggt acactcgagg tgggtggtca cgtcgaacta gcgctgcgag 120

<210> 718

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 718

tgtactcagg cgtctcgacg tcctactcga tgcgttcgag ctcctggtcg ttccgcgggt 60

acactcgagg tgggtggtca cgtcgaacta gcgctgcgag cctgcgcctt gaacgactac 120

<210> 719

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 719

acactcgagg tgggtggtca cgtcgaacta gcgctgcgag cctgcgcctt gaacgactac 60

acagcgcact tcctacagga acgctccctg gtactcctaa tcctcccctg acgtctgaac 120

<210> 720

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 720

cctgcgcctt gaacgactac acagcgcact tcctacagga acgctccctg gtactcctaa 60

tcctcccctg acgtctgaac ctttcctaca tacttagaaa tactataaaa tagtataaag 120

<210> 721

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 721

aaggtgtgtc tttatatgaa cgtagtatta aagtaatacg aaacgtaaaa tacagtataa 60

tggaaataaa tttattgtta ttataaggcg agagtctagt tagtctggtt cctccaagag 120

<210> 722

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 722

agagtctagt tagtctggtt cctccaagaa cgagactgga gtagggtata gacccatata 60

ggtctcgaga tttttataga agaatacgcc tagagaggaa taggggaggg acgcagggaa 120

<210> 723

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 723

gcgtgggtga accacgagac tgtgttcgaa gttaaacccc acgtgaacga gggagggagg 60

gaaggttggg tggaacgacc ctgggtcgca tggacgctaa ggaagtttca cgaagcgcct 120

<210> 724

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 724

aaggggttct ggacgcaaag tcagtctaca gaggagtccc tagactccca ggatatgcgc 60

tcgcttagta tttctcgtgt cgtcacgcta tgggtaggcg acgttcagtg catacacacg 120

<210> 725

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 725

agtggtattg agggtcgacg tgggtacttg gtcagttgtg tttccttaag ttggagaact 60

cgcaacgcac agagttggag aagacgcaca tctagaaaag tactctgata tggtgtctgg 120

<210> 726

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 726

ggtactgtcg tctatatccg cctcttgtta cttacaacgt gacgctagag gaccaggtca 60

caggacctct ttggactcga gtttccctct ctgtagcgag ggtaggtaac tcctcgcctg 120

<210> 727

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 727

tgtgagtgac ctattacact cctactagtg aggtagttct ggaagcgaaa ctcctaggaa 60

cgcagaacaa atatgtgtat cagtgggtag tatctgtgtg taaacgccag gtatcgaaca 120

<210> 728

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 728

ctaggcgcag gcgaatagag tcaccccgta tgtcgtcagt tccctcctct tacgatagga 60

ccgaccgtga tcagtatagg gttacctgag gtacgataga tatgaatagt gtaatatcgc 120

<210> 729

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 729

gacgacgtag taacctacga acaagtgtta cgtccttata tcctgtccct ttgagggtag 60

cgacctatag gggacacagt gtgtcgtcgc tactcccttc taccgcgaga tccctttcgc 120

<210> 730

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 730

tcgagggcgc tgcgctcgga ggcgtctcaa gacgctttcc ctctcgcctt ttcaacgctc 60

tcgcctactg tcctggcgta gtctctcgca cgagtaagag ctggttggga ccacactgag 120

<210> 731

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 731

ttctctgtga cctcgaggtc acgtcacctt gcgtcacagg ctgaacagaa tataactcag 60

aaaccgtatt tccttactct ctcgctggag ggtggtggag gcgtggtttg gggaagagtg 120

<210> 732

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 732

gcgtagtcga ttactaaggg tgggacgcaa acaggacgtg ccgcggtgga acgtagtggg 60

acgtagaagt gacgtctagg ggttcacgcg acgtttcacc tacgtgtagg acactgaagg 120

<210> 733

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 733

acgtccccac cccctgtaca cgcaggagga tacacacggg cgtgaggtcg agatacaggg 60

cgtcctcagg gaactcgacg tcgtctggtg tcacgaaggt tgggacgttc cgttttgcgt 120

<210> 734

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 734

tgcgctggcg tcgcctatac accaccccac ccatatccag ggactacgta aacgaagtga 60

caccttgcga cctgtgcgac acgctgagac acttatcagt cctcgcttcc tggtatgttg 120

<210> 735

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 735

caccacccca cccatatcca gggactacga taacgaagtg acaccttgcg acctgtgcga 60

cacgctgaga cacttatcag tcctcgcttc ctggtatgtt gggagtccct gggcgtctgt 120

<210> 736

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 736

cacgctgaga cacttatcag tcctcgcttc ctggtatgtt gggagtccct gggcgtctgt 60

cgactcacca tactagtacg cggagaaacg caggaccagg cggcgcacga ggcgagaggt 120

<210> 737

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 737

ggagtccctg ggcgtctgtg cactcaccaa tctagtacgc ggagaaacgc aggaccaggg 60

cgcgcacgag gcgagaggtc accacagaga ggtacacgga gagtgcgagg tgtgcgtccg 120

<210> 738

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 738

cgactcacca tactagtacg cggagaaacg caggaccagg cggcgcacga ggcgagaggt 60

caccacagag aggtacacgg agagtgcgag gtgtgcgtcc ggggtgggtg acactggaag 120

<210> 739

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 739

caccacagag aggtacacgg agagtgcgag gtgtgcgtcc ggggtgggtg acactggaag 60

acaggtccca ctggggttat gacaaccaca ccaggtctcc tttgagttgg tcccaagtca 120

<210> 740

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 740

acaggtccca ctggggttat gacaaccaca ccaggtctcc tttgagttgg tcccaagtca 60

gaataaacct gtatgactga gaccgtacgt acttcgtcct tccctaccgt ggagaccttg 120

<210> 741

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 741

gcgcctgagg cactggcgtc acagtgggga ggggtcctgt cgcctctcgt gcgcagacca 60

cacggaggta tcgtcgttgg tactggacac tactattcaa aagggactac gtaagtggac 120

<210> 742

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 742

cgactcgacg tgtgcgaggt aggggaggga cagaaagttt acaaaaccga taccagggtg 60

ttctggaacc cagaaaccta ttgtggtcta ggcgcaatac tcagcgttag gcgccctctg 120

<210> 743

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 743

ttctggaacc cagaaaccta ttgtggtcta ggcgcaatac tcagcgttag gcgccctctg 60

cctcccctgg ccctggtatg ttaccatacg aggagaccgc tacctcacgc acgaccgtcc 120

<210> 744

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 744

cctcccctgg ccctggtatg ttaccatacg aggagaccgc tacctcacgc acgaccgtcc 60

cgtggtcaca gaacgagtag accttgtgcg tttcagggtc ctagtgacta tcgtctacct 120

<210> 745

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 745

cgtggtcaca gaacgagtag accttgtgcg tttcagggtc ctagtgacta tcgtctacct 60

cacagtgact cgagtttaga tatacgttaa ttatcacttc cccgtgcgct tcctacacta 120

<210> 746

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 746

cacagtgact cgagtttaga tatacgttaa ttatcacttc cccgtgcgct tcctacacta 60

gtgacaagga gggagggtca gtcttggcgc gacgctcgct ccccactccc acgctcagta 120

<210> 747

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 747

gtgacaagga gggagggtca gtcttggcgc gacgctcgct ccccactccc acgctcagta 60

cttagtctcc aggtggtcac tgtgggtcgt ctggtggtcc ctgttcctag gtccctaagc 120

<210> 748

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 748

aggaacgttg cctcgcaggg accctaatat gtcgctctgt tacctggtaa caggtcagag 60

actctgaggt tttacgttgg tgggaggact gacctaacga agtttgttct cgtcgctgcg 120

<210> 749

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 749

actctgaggt tttacgttgg tgggaggact gacctaacga agtttgttct cgtcgctgcg 60

agagaacgta ccttttaaag ctggggtgta caggtacgcc agtggactga tgaaggaaac 120

<210> 750

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 750

agagaacgta ccttttaaag ctggggtgta caggtacgcc agtggactga tgaaggaaac 60

ccctacttcc cctacctatt cggggtctat gtttgagcgt cgtatcgccg ctgagtacga 120

<210> 751

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 751

ccctacttcc cctacctatt cggggtctat gtttgagcgt cgtatcgccg ctgagtacga 60

aaccagacga gagtttaaca ttcacggtgg gtcgcaaata cttaacacac acacacgtca 120

<210> 752

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 752

aaccagacga gagtttaaca ttcacggtgg gtcgcaaata cttaacacac acacacgtca 60

gtgggcgtag cacgtctgcg caaagttagg gggtcactgg ggacctcagg gcgagggtag 120

<210> 753

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 753

cctaggtcgc tctcccagga ctggtcagga tggtacgact gaagagttcg tcttcacgcc 60

ctatgggtca gggttggggt gtgcgggcgt gtcgggtatg cgggaataga cgccctgtgg 120

<210> 754

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 754

cacggtcata cgaaaacaca gacacgaaca ccacagacga tcgtacgtat cgtcctatac 60

tgtggggacg ggggacgcta cgtctcccag cctctcacgt tcagaagcgt ctcgtgactc 120

<210> 755

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 755

gggaggcgag gcgagggagg tgaggacgct aggactaacg agggagggag tgacaccttg 60

aacacgatac tactttacct tatatacctc ccgctcctcc acctgaggag cagtatcgtc 120

<210> 756

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 756

aacacgatac tactttacct tatatacctc ccgctcctcc acctgaggag cagtatcgtc 60

cagtatgtcc gaaagtatgt cttgtctccc agtatgactt cttctagcgc ttcacgcagg 120

<210> 757

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 757

cagtatgtcc gaaagtatgt cttgtctccc agtatgactt cttctagcgc ttcacgcagg 60

atagtcctcc ggtgcgaccc tcctcgaaag tatttccgcg ccagacgaag gaagtgttta 120

<210> 758

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 758

atagtcctcc ggtgcgaccc tcctcgaaag tatttccgcg ccagacgaag gaagtgttta 60

ctatccacgc acctccacca cctcggggaa gagtaaggga acctcggtga ggtacgtgcg 120

<210> 759

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 759

ctatccacgc acctccacca cctcggggaa gagtaaggga acctcggtga ggtacgtgcg 60

aaggttcata tacgctacgt gcgcagagaa cgaggtacga ggaccgcttg gaggcgcgcc 120

<210> 760

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 760

aaggttcata tacgctacgt gcgcagagaa cgaggtacga ggaccgcttg gaggcgcgcc 60

cgaccacgtc cacgtcccgg gcgcctactt cagtgggcgc ttcacgcttc agtaccacac 120

<210> 761

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 761

ggtatacggt accatatatc agacgtccta cgtacccagg tcgcagtgac taagtacgcc 60

tcagcgtacg gtagcgtacg ggcgccacgt gaagcgctgg gagaggttct gggagaggcg 120

<210> 762

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 762

tcagcgtacg gtagcgtacg ggcgccacgt gaagcgctgg gagaggttct gggagaggcg 60

accgttcgag ccgtttacct cggcgtccgg atatcgcgtt tacgcctaga accgaggagt 120

<210> 763

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 763

accgttcgag ccgtttacct cggcgtccgg atatcgcgtt tacgcctaga accgaggagt 60

ttatctccag gactggtggg tggaacgtgt ctgtcttgcg cccgtagcgc ctcgcaccac 120

<210> 764

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 764

ttatctccag gactggtggg tggaacgtgt ctgtcttgcg cccgtagcgc ctcgcaccac 60

ctccgcgtcg atagtacagg gcgaccgcga ctcctacctt ctactgacca ggggagacta 120

<210> 765

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 765

ctccgcgtcg atagtacagg gcgaccgcga ctcctacctt ctactgacca ggggagacta 60

tcagactatg agaaaccgag ctgtcgttcc ccctggacgc cctaacgtct ggtaatatca 120

<210> 766

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 766

tcagactatg agaaaccgag ctgtcgttcc ccctggacgc cctaacgtct ggtaatatca 60

acctgactga gggtttcgtg ttttggggtg acctggtgac ctctcagtgg tctgaggtgg 120

<210> 767

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 767

ccaggcgtgt ctagagcgtc tgactatcga gtacgacagg aacctggtgg aatactgcga 60

cgacacacca taccttaata acgtaggtgg ctccagtatg tcctcctccg cctcctcgcc 120

<210> 768

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 768

gtggaatact gcgacgacac acctaacctt aataacgtag gtgcgtccac cccctcctcc 60

tcccgctcct cgccactcta cgaccgttct gttcacacgg tattcttctt cttacactat 120

<210> 769

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 769

ccagtatgtc ctcctcccgc tcctcgccac tctacgaccg ttctgttcac acggtattct 60

tcttcttaca ctatgttctc tccatacgag actttctgga ttaactggtt tgtctgtaga 120

<210> 770

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 770

tcacacggta ttcttcttct tacactatgt gactgcgata cgagactttc tggtataact 60

ggtttgtctg tagaaacaaa aacgacgtta ggtttgtgcg caaaccagag ttctccactt 120

<210> 771

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 771

tttctggtat aactggtttg tctgtagaaa ccgtagcgac gttaggtttg tgcgcaaacc 60

agagttctcc actttcgacg agacagaact tcttacgtta aaaacaggta ctgactctct 120

<210> 772

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 772

gtttatatac tctttcgtgt ctctatctcc tggttagaac ttccaggagg agggtgttga 60

gtgttggtcg ctccaagagg ccttcccggg cgctgacaga gtcgagacga gaaacccctg 120

<210> 773

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 773

gtgttggtcg ctccaagagg ccttcccggg cgctgacaga gtcgagacga gaaacccctg 60

ctctggcgac ttacactggg cgagcggtcc tctccctcgt cgccaaccag gtagtacacg 120

<210> 774

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 774

ctctggcgac ttacactggg cgagcggtcc tctccctcgt cgccaaccag gtagtacacg 60

tagtctacct tctccaggtt gaagtacgcc acgacagaca ccgcgtggga cccgtactag 120

<210> 775

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 775

tagtctacct tctccaggtt gaagtacgcc acgacagaca ccgcgtggga cccgtactag 60

gtgttcttcc ccgctttccc cgcacgacgt ccgtacgccg agtacgtcga tagggacaaa 120

<210> 776

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 776

gtgttcttcc ccgctttccc cgcacgacgt ccgtacgccg agtacgtcga tagggacaaa 60

gaacgttgcg tccccgtgtg gttagaagac tgtgtatgtt cctcgcaacc cacgacgttc 120

<210> 777

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 777

gaacgttgcg tccccgtgtg gttagaagac tgtgtatgtt cctcgcaacc cacgacgttc 60

cagtggcgta acgactaccg ctacgtggtc tgagggttct gtatgtatac agtccctcga 120

<210> 778

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 778

ggcgctgagt ctgttcgctt tgaaccttga ctacgctggg caccccagga actacgaccc 60

taagcgaaga ctccagcgtt cttcggaagg ggtggtctcg ccctcccctc cccctcttcc 120

<210> 779

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 779

taagcgaaga ctccagcgtt cttcggaagg ggtggtctcg ccctcccctc cccctcttcc 60

taaccgacct gtaggtgtcg gtgcgtgcga ccttccagta ctggtacgct ttctacacgc 120

<210> 780

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 780

taaccgacct gtaggtgtcg gtgcgtgcga ccttccagta ctggtacgct ttctacacgc 60

cctccgtccc cacctccacg ctcaggttgg agttctggta gcggttgttg cactgtcgct 120

<210> 781

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 781

cctccgtccc cacctccacg ctcaggttgg agttctggta gcggttgttg cactgtcgct 60

gggtgggcgc tagggcgccg ctgcgcccac tagtggtgaa cacgcataga actgtgcgac 120

<210> 782

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 782

gggtgggcgc tagggcgccg ctgcgcccac tagtggtgaa cacgcataga actgtgcgac 60

aagaggagag cgagtcactc tagtgcgcag cgcctccctc ctccagggcg ctccctgggt 120

<210> 783

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 783

aagaggagag cgagtcactc tagtgcgcag cgcctccctc ctccagggcg ctccctgggt 60

gcgctctgag tatactcgtc ctagcgccca aaccctccta ccaagtagcg accaaggtca 120

<210> 784

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 784

cctgttctca gcgctgtttc tttcctgtct ttatacttgt acagtacgtg taacctacga 60

ggtcttgtgg ttgttggtcg tttgacctta ctcacttcga ttttgaagtt ttaggggata 120

<210> 785

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 785

ctaaagactg tttctatctt tcacgacacg tccccaccct aaagacacga ccatactttc 60

ttctcgcttt tcgaacaaga agttactgtg ctcactattg tgacgtgaac ccttacctgt 120

<210> 786

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 786

ttctcgcttt tcgaacaaga agttactgtg ctcactattg tgacgtgaac ccttacctgt 60

agggtcaaag tatcacgtct gtcttggtga tatttccccg ggtttcacgt ccttgtttgg 120

<210> 787

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 787

agggtcaaag tatcacgtct gtcttggtga tatttccccg ggtttcacgt ccttgtttgg 60

gttgactgga aacaggtttc ttgtattggg tcgtgttatc tcgaggtact tgtcctctcc 120

<210> 788

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 788

gttgactgga aacaggtttc ttgtattggg tcgtgttatc tcgaggtact tgtcctctcc 60

cgtaactcga taagagaaga ccccacggcg tgagttaggt gagggttgta ttcagggtga 120

<210> 789

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 789

cgtaactcga taagagaaga ccccacggcg tgagttaggt gagggttgta ttcagggtga 60

gagtagtatt cacactgagg gaggtgggag agacagtcag cgttagcgtg aggaggggac 120

<210> 790

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 790

gtattcaggg tgagagtaga tttcacactg agggaggtgg gagagacagt cagcgttagg 60

ctgaggaggg gacatagagg cctaggcgca ttcacgttgg gggacagagt cgtggggtca 120

<210> 791

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 791

ctgaggaggg gacatagagg cctaggcgca ttcacgttgg gggacagagt cgtggggtca 60

gagtgaactc actggtgagg tacgagtcca gcgtgtagga gtatatgtca aaacgcacga 120

<210> 792

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 792

gagtgaactc actggtgagg tacgagtcca gcgtgtagga gtatatgtca aaacgcacga 60

tgcgtctgga tccttgtccc cacctacgga cctactcgag ccagaacctg tacactacaa 120

<210> 793

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 793

tgcgtctgga tccttgtccc cacctacgga cctactcgag ccagaacctg tacactacaa 60

gaggatagtg tgtgaggacg aaacttcacg gtcttgtctt aggtatcacg taccacgagg 120

<210> 794

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 794

gaggatagtg tgtgaggacg aaacttcacg gtcttgtctt aggtatcacg taccacgagg 60

tgtgtcgtga tcacctgcgt cagatagtga gtttgcgtag gcgtccgtaa tcccagacga 120

<210> 795

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 795

tttagagcgt ttgtggagaa gaacggtgta catacgtcag ctaacgtaaa tgaagaagag 60

actatctcaa gtgacactct gtaagtagcg cagactagag acgttatatc cttgacttag 120

<210> 796

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 796

tacggtgtgt ggcgactact cgtagtgtgt cttgggtaaa agcgacgggg aaagggaagg 60

ctagtattct ttttctattt acgtgtaaga ggagaagggt tattcacgag tacgtaagag 120

<210> 797

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 797

ctagtattct ttttctattt acgtgtaaga ggagaagggt tattcacgag tacgtaagag 60

cctacctgtc agacactacg aggagagcga acacctacca ctcgcacagg ctcaacgctt 120

<210> 798

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 798

cctacctgtc agacactacg aggagagcga acacctacca ctcgcacagg ctcaacgctt 60

ctaagcggcg gactacgcag acctacctcg cttcgtcctt cccggttttg ttctccacta 120

<210> 799

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 799

ctaagcggcg gactacgcag acctacctcg cttcgtcctt cccggttttg ttctccacta 60

cgaccaagga cacgtttccc ctcaagactc cacgatagag ccaggactat cggacgtgtg 120

<210> 800

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 800

cgaccaagga cacgtttccc ctcaagactc cacgatagag ccaggactat cggacgtgtg 60

aggcggagaa gagtcagagg acaaggttag tatcgtgaaa ggtccccttt ctggatatct 120

<210> 801

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 801

aggcggagaa gagtcagagg acaaggttag tatcgtgaaa ggtccccttt ctggatatct 60

ccactgaagt ttcaaggacc tttaaagaga ctcacgtgag ttcacgctgg tgagaagacg 120

<210> 802

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 802

ctccacgact ggactaagtg aagcgttctt tctactaggg tcgaaagacg tagggtgttc 60

gaagcgcctc tataagataa tagcgttcgt tttcacgtaa taacacgcaa gtgtattgta 120

<210> 803

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 803

ggtgcgcctc ttgtgactgg cccaggagaa cgaccacgcc acgcacgtag cgtactttct 60

tatactgggt tccggaagtg acaagaggtg ggaggagaaa ttagagaact agagaaacaa 120

<210> 804

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 804

tatactgggt tccggaagtg acaagaggtg ggaggagaaa ttagagaact agagaaacaa 60

ggagacttcg ctcactagga gacgtcttga tcggtcgagg aaacgtacga ctggtcactg 120

<210> 805

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 805

ggagacttcg ctcactagga gacgtcttga tcggtcgagg aaacgtacga ctggtcactg 60

tacgactttc agaacggggg actacagtgg tactgacgaa tagacgtagg tctaggagag 120

<210> 806

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 806

tacgactttc agaacggggg actacagtgg tactgacgaa tagacgtagg tctaggagag 60

aggaaaagaa tcacaacgac cgctattaca ggaactgggg gaccaggggt cgagggttaa 120

<210> 807

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 807

aggaaaagaa tcacaacgac cgctattaca ggaactgggg gaccaggggt cgagggttaa 60

tggactgtcg acagttctta tctacgctag ggtatacttt gaggaaacag gtttctgcgc 120

<210> 808

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 808

ggtcagacac ccgacgttcg cctcgaggtg gggtgaagtc cacgcctgag tctccctact 60

gtcttagtgg cgtagaagta ggcgaccaga gagaagcgag gagacgagta gtaccttggt 120

<210> 809

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 809

gtcttagtgg cgtagaagta ggcgaccaga gagaagcgag gagacgagta gtaccttggt 60

ggtcctggaa ccggcgtacc tttagggtcc tgacctcgca ttgaggagtg tggggtgaca 120

<210> 810

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 810

ggtcctggaa ccggcgtacc tttagggtcc tgacctcgca ttgaggagtg tggggtgaca 60

gtgtcgcttg ggtccacgca cagaacgcta cttcaaagtt cgagtcgtag cccacagcga 120

<210> 811

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 811

gtgtcgcttg ggtccacgca cagaacgcta cttcaaagtt cgagtcgtag cccacagcga 60

gtttccctta ggagagacga gagagcgacc tactatttca ggaccactaa agcgaaataa 120

<210> 812

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 812

gtttccctta ggagagacga gagagcgacc tactatttca ggaccactaa agcgaaataa 60

tcgcatacgc aagtcgatat acgcagcgta gaccaatata tcttctatag tatataacgt 120

<210> 813

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 813

gtgtcagtgg tatacaggaa gcgtgtccta cgtctctacg ctgggtaata ggggacaacg 60

gggtttagag ctaggcgtgg cgtcagcgag ggtgggcgag cccctactac tcacgcgaca 120

<210> 814

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 814

gggtttagag ctaggcgtgg cgtcagcgag ggtgggcgag cccctactac tcacgcgaca 60

tctgcgtctc tacttctccc tggcgacagt cctggtggaa gtcacagcgc tcgccaacgt 120

<210> 815

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 815

tctgcgtctc tacttctccc tggcgacagt cctggtggaa gtcacagcgc tcgccaacgt 60

ggaggactgt ccctatccaa caagtgaagg acgtctcgag gcgctacttg gacgctgggg 120

<210> 816

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 816

ggaggactgt ccctatccaa caagtgaagg acgtctcgag gcgctacttg gacgctgggg 60

tagttcctgg agacgacaca gacacacaac ctaggtaagt ttcgtagcgc ccagcgacga 120

<210> 817

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 817

tagttcctgg agacgacaca gacacacaac ctaggtaagt ttcgtagcgc ccagcgacga 60

cgtgcgctga tgggttggtc cctaggcgag cgtcgaggga cacgtattac ctcgcctcgc 120

<210> 818

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 818

gggttcactc actgagatag tacgctcttc cctatattag ctatcgaaac agaaacccta 60

cgtacctctg ctctttcata cgtgttttag agtattgtag ctacaaaacc tacacaactc 120

<210> 819

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 819

gaacctctcg ctagagggtt ttcgtcgaag ggacacgtgt aggggtttcg tgtgtcttta 60

taaaaccttt ccctacaact tgtaacagcg tgagaactgg tcttcaagga caacaggcgt 120

<210> 820

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 820

aaaggacgct ttagcgtacg taacactcga cgtaccacac acaaaccacg tgggactagt 60

gtctatcctg gtaggagtca aggtttcgta tcggcgcata cgccctccct tgaagagggt 120

<210> 821

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 821

cacgctcagg cctgtcgctg gacgaagacg acacgagcgt tcactgtaga cggacgtgga 60

cactaggtac agacagcgaa ttccacgcgc caggtttctt cccttcacaa aaggaaagga 120

<210> 822

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 822

ccactctaga cttttcttca taagtgtcga ctatcccacg caaactaggt tcgaggttta 60

tgacactact aacacataag cgtaccaagg acggtgggaa acgcagtatc agtaaccttc 120

<210> 823

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 823

tgacactact aacacataag cgtaccaagg acggtgggaa acgcagtatc agtaaccttc 60

actcgagttc ttcaggcgaa agaagtccac tcgagacaag ctcgggtttc cactggagta 120

<210> 824

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 824

actcgagttc ttcaggcgaa agaagtccac tcgagacaag ctcgggtttc cactggagta 60

gttatccagg cgcactcgaa tagggttgtc tggaccgccg tatcttccct ggacgactgt 120

<210> 825

<211> 120

<212> DNA

<213>Artificial sequence (Artificial Sequence)

<400> 825

cagctcagat acttctgtgt gacaaccgca ccagccaggt catctactaa acacaaagta 60

acagagagca tcttaaacat gacctgtcat atccagggga ctgtatgaca aaggtaagat 120

Claims (11)

1. a kind of capture probe based on high-flux sequence detection human genome mutational load, the capture probe include capture and visited Pin 1, capture probe 2 and capture probe 3, the sequence such as SEQ ID NO of the capture probe 1:Shown in 1~275, the capture is visited The sequence of pin 2 such as SEQ ID NO:Shown in 276~550, the sequence such as SEQ ID NO of the capture probe 3:551~825 institutes Show.

2. capture probe according to claim 1, wherein, the capture probe includes 21108 probes, preferably comprises 10333 probes.

3. capture probe according to claim 1 or 2, wherein, the Tm values of the capture probe are 65-75 DEG C.

4. according to the capture probe described in claim any one of 1-3, wherein, the concentration of the capture probe for 0.1PM~ 6PM, preferably 1.5PM.

5. according to the capture probe described in claim any one of 1-4, wherein, the capture probe covering gene group 0.8Mb- 2.4Mb region, preferably 0.8Mb-1.2Mb regions, more preferably 1.2Mb regions.

6. the capture probe described in claim any one of 1-5, it is detecting human genome mutational load based on high-flux sequence In application.

7. a kind of method based on high-flux sequence detection human genome mutational load, it includes following step：

(1) the genomic DNA double-strandednucleic acid in blood and tissue samples is extracted；

(2) the DNA double chain nucleic acid denaturation of step (1) handles to obtain to DNA is single-stranded, and usage right requires any one of 1-5 institute The DNA described in capture probe capture stated is single-stranded；

(3) the single-stranded progress higher level's sequencings of DNA captured step (2), obtain the nucleotide sequence in blood and tissue samples；

(4) nucleotide sequence obtained by step (3) is subjected to automatic business processing, removes variation information and background signal, calculating group The variant sites number in sample is knitted, it is big according to formula mutational load=sample measures region variation sum/sample measures region It is small to obtain mutational load number.

8. the method according to claim 7 based on high-flux sequence detection human genome mutational load, wherein, in step (1) in, fragmentation processing is carried out after genomic DNA double-strandednucleic acid is extracted, it is 100-1000bp to obtain fragment length, preferably , fragment length 100-500bp, it is furthermore preferred that fragment length is 200-300bp.

9. the method based on high-flux sequence detection human genome mutational load according to claim 7 or 8, wherein, In step (4), the mensuration region of the sample is 0.8-2.4Mb, preferably 0.8-1.2Mb, more preferably 1.2Mb.

10. a kind of kit based on high-flux sequence detection human genome mutational load, wherein, the kit includes right It is required that capture probe described in any one of 1-5 and repairing reaction buffer, DNA ligase, company selected from end repair enzyme, end Connect the reaction buffer, joint containing molecular label, amplified library primer, PCR premixed liquids, tab closure agent, DNA sealers, miscellaneous Hand over buffer solution, hybridization enhancers, magnetic bead washing lotion, hybridization washing lotion, capture library PCR primer, quality-control product I and II, nucleic acid purification magnetic Pearl and one or more reagents of streptavidin magnetic bead.

11. the kit according to claim 10 based on high-flux sequence detection human genome mutational load, wherein, institute State kit and repair reaction buffer, DNA comprising the capture probe described in claim any one of 1-5, end repair enzyme, end Ligase, coupled reaction buffer solution, the joint containing molecular label, amplified library primer, PCR premixed liquids, tab closure agent, DNA Sealer, hybridization buffer, hybridization enhancers, magnetic bead washing lotion, hybridization washing lotion, capture library PCR primer, quality-control product I and II, core Acid purifying magnetic bead and streptavidin magnetic bead.