CN107485678A - A kind of pill medicine and preparation method for treating headache and palpitation and insomnia - Google Patents

A kind of pill medicine and preparation method for treating headache and palpitation and insomnia Download PDF

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Publication number
CN107485678A
CN107485678A CN201710871309.1A CN201710871309A CN107485678A CN 107485678 A CN107485678 A CN 107485678A CN 201710871309 A CN201710871309 A CN 201710871309A CN 107485678 A CN107485678 A CN 107485678A
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medicine
insomnia
palpitation
headache
chinese
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罗倩茹
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Sichuan Juhao Biotechnology Co Ltd
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Sichuan Juhao Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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  • Health & Medical Sciences (AREA)
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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of pill medicine for treating headache and palpitation and insomnia provided according to the understanding mechanism of Chinese traditional treatment headache and palpitation and insomnia, each component and its mass parts ratio of the medicine are as follows:90~350g of aleppo avens, 30~100g of red ginseng, 150~350g of pittosporum illicioides, 30~120g of Ligusticum wallichii, 30~60g of frankincense, 60~150g of lily, 60~150g of cacumen biotae, 150~300g of the Radix Astragali, 30~120g of the root of Dahurain angelica, windproof 50~120g, 30~120g of safflower, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of pill medicine and preparation method for treating headache and palpitation and insomnia
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating headache and palpitation and insomnia, especially It is the pill medicine and its system for having a headache and palpitation and insomnia patient uses
The field of Preparation Method.
Background technology
Doctor thinks:Palpitation and insomnia, palpitaition include palpitation with fear and palpitation, are names of disease of tcm.Refer to patient to feel in the heart to throb with fear It is dynamic, a kind of terrified uneasy, symptom that very then can not be independently.Insomnia refers to often obtain for normally sleep.It is insomnia Situation has a variety of, or is not easy to fall asleep, or sleep but easy to wake, can not be fallen asleep once again after waking up, or even lie awake all night.Headache(headache) It is clinical common symptom, generally will be limited to the head first half, including geisoma, helix upper limb and the outer knuckle line of pillow with top The pain of position is referred to as headache.Headache is because various, neuralgia, intracranial infection, intracranial space-occupying lesion, cranial vascular disease, cranium the outside Maxillofacial disease and general disease such as acute infection, poisoning etc. can cause to have a headache.Age of onset be common in the young, middle age and It is old.
Clinical manifestation:Headache degree has and gently has weight, and pain time has with short.Pain form is varied, common swollen Bitterly, vexed pain, tear sample pain, electric shock sample pain, prickling-like pain, partly with vascular pulsation sense and head lock ring sense, and nausea, The symptoms such as vomiting, dizziness.Secondary headache can be also often accompanied by with other systems disease symptomses or sign, such as infectious diseases Heating, vascular lesion is often with neurologic impairment symptoms such as hemiplegia, aphasia etc..Headache produces different harm, the state of an illness according to degree Patient can be seriously set to lose live and work ability.
So, it is art technology with regard to how to find a kind of Chinese medicine composition that can effectively treat headache and palpitation and insomnia The problem of personnel are urgently to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment headache and palpitation and insomnia, people gradually appreciate The advantages of Chinese traditional treatment headache and palpitation and insomnia, and good effect, advantage, the pin such as quick, toxic side effect is small over the course for the treatment of To the headache of existing western medical treatment and the present situation of palpitation and insomnia, the purpose of the present invention is to be that providing one kind treats headache and palpitaition mistake The pill medicine of dormancy, to solve the problems, such as that headache and palpitation and insomnia patient are got well early.The medicine is with common Chinese medicine For raw material, by selecting rational medicine and its mass parts ratio, above-mentioned headache and palpitation and insomnia can be effectively treated.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:One kind is provided and treats headache and palpitaition The pill medicine and preparation method of insomnia, it is characterised in that the medicine
Each component and its mass parts than as follows:
90~350g of aleppo avens, 30~100g of red ginseng, 150~350g of pittosporum illicioides, 30~120g of Ligusticum wallichii, 30~60g of frankincense, lily 60~150g, 60~150g of cacumen biotae, 150~300g of the Radix Astragali, 30~120g of the root of Dahurain angelica, windproof 50~120g, 30~120g of safflower, Auxiliary material:Appropriate starch.
It is a kind of treat headache and palpitation and insomnia pill medicine and preparation method, it is characterised in that the medicine it is each Component and its mass parts are than as follows:
100~310g of aleppo avens, 38~90g of red ginseng, 180~310g of pittosporum illicioides, 38~105g of Ligusticum wallichii, 38~52g of frankincense, lily 70~120g, 70~130g of cacumen biotae, 180~260g of the Radix Astragali, 38~105g of the root of Dahurain angelica, windproof 58~105g, 38~105g of safflower, Auxiliary material:Appropriate starch.
It is a kind of treat headache and palpitation and insomnia pill medicine and preparation method, it is characterised in that the medicine it is each Component and its mass parts are than as follows:
Aleppo avens 260g, red ginseng 80g, pittosporum illicioides 260g, Ligusticum wallichii 95g, frankincense 46g, lily 105g, cacumen biotae 118g, the Radix Astragali 230g, root of Dahurain angelica 95g, windproof 95g, safflower 95g, auxiliary material:Appropriate starch.
A kind of pill medicine and preparation method for treating headache and palpitation and insomnia, it is characterised in that methods described is included such as Lower step is prepared:
A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With;
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent(The granularity of its water-bindered pill is:3.8mm~4.0mm), and then dry, sealed packaging is Can.
A kind of pill medicine and preparation method for treating headache and palpitation and insomnia, it is characterised in that the instructions of taking is: By the water pill medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, and dosage 5g/time(Children are cut down according to the circumstance), Wen Kai Water delivery service.15 days are a course for the treatment of, and 2~3 courses for the treatment of of taking medicine, symptom disappears, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Aleppo avens, nature and flavor:It is sweet, slight bitter, cool in nature, have replenish qi to invigorate the spleen, yin-nourishing of enriching blood, moistening lung for removing phlegm the effect of, for treating Insufficiency of vital energy and blood, tuberculosis cough, lukorrhagia due to hypofunction of the spleen;
Red ginseng, nature and flavor:Sweet, slight bitter, temperature, there is the effect of reinforcing vital energy, veins takes off admittedly, nourishing qi to stop, for treating physically weak desire De-, cold weak pulse of limb, Qi dysfunction in blood control, metrostaxis;
Pittosporum illicioides, nature and flavor:It is bitter, pungent, warm, there is the effect of active pain relieving, heart-calming kidney-nourishing, removing toxic substances, for treating arthralgia pain due to rheumatism, bone Folding, stomachache, insomnia, seminal emission, venomous snake bite;
Ligusticum wallichii, nature and flavor:It is acrid flavour, warm-natured, there is the effect of promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping, for treating menstruation not The stagnant raw meat pain of tune, closed dysmenorrhea, the postpartum stasis of blood, abdominal mass lump, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sore Ulcer;
Frankincense, nature and flavor:Acrid, bitter, warm, there is the effect of blood-activating and qi-promoting analgesic, detumescence and promoting granulation, for treating chest impediment and cardialgia, gastral cavilty Pain, dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass stomachache, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore;
Lily, nature and flavor:Sweet, slight bitter, it is slightly cold, there is the effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, coughed long, in phlegm for treating the deficiency of Yin With blood, pyreticosis later stage, waste heat be not clear or feelings will it is unsuccessful caused by dysphoria palpitates with fear, insomnia and dreamful sleep, absent-minded, carbuncle swells, wet sore etc. Disease;
Cacumen biotae, nature and flavor:It is bitter, puckery, cold, there is the effect of cooling blood and hemostasis, growing and blacking hair, for treating hematemesis and epistaxis, spitting of blood, just The illnesss such as blood, metrostaxis, blood-head alopecia, poliosis;
The Radix Astragali, nature and flavor:Sweet, tepor, there is the effect of solid table of polishing, torr sore myogenic, for treat physically weak spontaneous perspiration, chronic diarrhea, prolapse of the anus, The prolapse of uterus, chronic nephritis, physically weak edema, chronic ulcer, the long disunion of the open sore part;
The root of Dahurain angelica, nature and flavor:It is acrid flavour, warm-natured, there is dispelling wind and eliminating dampness, logical the effect of stealing analgesic, detumescence and apocenosis, for treating head of catching a cold Bitterly, pain in the supra-orbital bone, toothache, nasal obstruction, nasosinusitis, wet victory chronic diarrhea, women leukorrhea, ulcer sores, venomous snake bite;
It is windproof, nature and flavor:Acrid flavour, sweet, slightly warm in nature, have expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, spasmolysis, it is antipruritic the effect of, it is outer for treating Feel chill, headache bodily pain, arthralgia pain due to rheumatism, skeletal pain, stomachache diarrhea, discharging fresh blood stool, lockjaw, rubella itch, sore from the beginning of;
Safflower, nature and flavor:Warm-natured, acrid flavour, there is the effect of invigorate blood circulation, blood stasis removing analgesic, for treating Amenorrhea, dysmenorrhoea, bruise damage Wound, lochia, abdominal mass lump in the abdomen, hemorrhoid gall.
Medicine of the present invention is the principle based on Chinese traditional treatment headache and palpitation and insomnia, from the disease according to headache and palpitation and insomnia Reason mechanism and pharmacological action are thought:With regard to headache and palpitation and insomnia, each raw material herbal medicine efficacy in medicine provided by the present invention is total to Play, have good therapeutic effect to above-mentioned disease.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at above-mentioned headache and the treatment of palpitation and insomnia, using the formula The medicine effect of preparation is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the present invention Embodiment be described in further detail:
Embodiment 1:
A kind of pill medicine for treating headache and palpitation and insomnia, it is characterised in that each component and its mass parts of the medicine Than as follows:
Aleppo avens 260g, red ginseng 80g, pittosporum illicioides 260g, Ligusticum wallichii 95g, frankincense 46g, lily 105g, cacumen biotae 118g, the Radix Astragali 230g, root of Dahurain angelica 95g, windproof 95g, safflower 95g, auxiliary material:Appropriate starch.
Embodiment 2:
A kind of pill medicine for treating headache and palpitation and insomnia, it is characterised in that each component and its mass parts of the medicine Than as follows:
Aleppo avens 310g, red ginseng 90g, pittosporum illicioides 310g, Ligusticum wallichii 105g, frankincense 52g, lily 120g, cacumen biotae 130g, the Radix Astragali 260g, root of Dahurain angelica 105g, windproof 105g, safflower 105g, auxiliary material:Appropriate starch.
Embodiment 3:
A kind of pill medicine for treating headache and palpitation and insomnia, it is characterised in that each component and its mass parts of the medicine Than as follows:
Aleppo avens 350g, red ginseng 100g, pittosporum illicioides 350g, Ligusticum wallichii 120g, frankincense 60g, lily 150g, cacumen biotae 150g, the Radix Astragali 300g, root of Dahurain angelica 120g, windproof 120g, safflower 120g, auxiliary material:Appropriate starch.
Curative effect determinate standard:According to《Chinese medical disease Standardization of diagnosis and curative effect》
Model case is as follows:
Through clinical conditions headache and palpitation and insomnia patient totally 1190, the age is 690, only 500 of more than 32 years old For less than 32 years old.690 to be fully recovered in 1190 patients, effective 429, invalid 71.Total effective rate is up to 94%.

Claims (3)

1. a kind of pill medicine for treating headache and palpitation and insomnia, it is characterised in that each component and its quality of the medicine Part is than as follows:
90~350g of aleppo avens, 30~100g of red ginseng, 150~350g of pittosporum illicioides, 30~120g of Ligusticum wallichii, 30~60g of frankincense, lily 60~150g, 60~150g of cacumen biotae, 150~300g of the Radix Astragali, 30~120g of the root of Dahurain angelica, windproof 50~120g, 30~120g of safflower, Auxiliary material:Appropriate starch.
2. it is according to claim 1 treatment headache and palpitation and insomnia pill medicine, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows:
100~310g of aleppo avens, 38~90g of red ginseng, 180~310g of pittosporum illicioides, 38~105g of Ligusticum wallichii, 38~52g of frankincense, lily 70~120g, 70~130g of cacumen biotae, 180~260g of the Radix Astragali, 38~105g of the root of Dahurain angelica, windproof 58~105g, 38~105g of safflower, Auxiliary material:Appropriate starch.
3. the pill medicine of the treatment headache and palpitation and insomnia according to claim 1 to 2, it is characterised in that the medicine Each component and its mass parts than as follows:
Aleppo avens 260g, red ginseng 80g, pittosporum illicioides 260g, Ligusticum wallichii 95g, frankincense 46g, lily 105g, cacumen biotae 118g, the Radix Astragali 230g, root of Dahurain angelica 95g, windproof 95g, safflower 95g, auxiliary material:Appropriate starch.
CN201710871309.1A 2017-09-25 2017-09-25 A kind of pill medicine and preparation method for treating headache and palpitation and insomnia Pending CN107485678A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101780131A (en) * 2010-03-26 2010-07-21 鲍旭刚 Drug for treating headache and preparation method thereof
CN102178850A (en) * 2010-12-14 2011-09-14 深圳市康宁堂大药房 Medicament for treating headache
CN105363016A (en) * 2015-12-28 2016-03-02 杨玲林 Medicine for treating headache
CN106166221A (en) * 2016-09-20 2016-11-30 四川兴聚焦医药科技有限责任公司 A kind of treat headache, insomnia, cardiopalmus and weak Chinese medicine composition
CN106177149A (en) * 2016-09-08 2016-12-07 四川聚豪生物科技有限公司 A kind of for capsule medicine treating headache and preparation method thereof
CN106822779A (en) * 2017-02-16 2017-06-13 成都富豪斯生物科技有限公司 A kind of Chinese medicine composition of the obstruction of qi in the chest and palpitation and insomnia for treating caused by energy stagnation and blood stasis

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101780131A (en) * 2010-03-26 2010-07-21 鲍旭刚 Drug for treating headache and preparation method thereof
CN102178850A (en) * 2010-12-14 2011-09-14 深圳市康宁堂大药房 Medicament for treating headache
CN105363016A (en) * 2015-12-28 2016-03-02 杨玲林 Medicine for treating headache
CN106177149A (en) * 2016-09-08 2016-12-07 四川聚豪生物科技有限公司 A kind of for capsule medicine treating headache and preparation method thereof
CN106166221A (en) * 2016-09-20 2016-11-30 四川兴聚焦医药科技有限责任公司 A kind of treat headache, insomnia, cardiopalmus and weak Chinese medicine composition
CN106822779A (en) * 2017-02-16 2017-06-13 成都富豪斯生物科技有限公司 A kind of Chinese medicine composition of the obstruction of qi in the chest and palpitation and insomnia for treating caused by energy stagnation and blood stasis

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Application publication date: 20171219