CN107462566B - 用于检测特定窄波数范围的拉曼光谱仪 - Google Patents
用于检测特定窄波数范围的拉曼光谱仪 Download PDFInfo
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- CN107462566B CN107462566B CN201710685154.2A CN201710685154A CN107462566B CN 107462566 B CN107462566 B CN 107462566B CN 201710685154 A CN201710685154 A CN 201710685154A CN 107462566 B CN107462566 B CN 107462566B
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- 238000001069 Raman spectroscopy Methods 0.000 title claims abstract description 72
- 238000001228 spectrum Methods 0.000 claims abstract description 23
- 230000005284 excitation Effects 0.000 claims abstract description 19
- 238000001237 Raman spectrum Methods 0.000 claims abstract description 18
- 238000012545 processing Methods 0.000 claims abstract description 11
- 238000001914 filtration Methods 0.000 claims abstract description 5
- 230000035945 sensitivity Effects 0.000 claims description 14
- 230000003287 optical effect Effects 0.000 claims description 9
- 239000000758 substrate Substances 0.000 claims description 5
- 230000000149 penetrating effect Effects 0.000 claims description 4
- 230000002238 attenuated effect Effects 0.000 claims description 2
- 238000003384 imaging method Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 9
- 239000000523 sample Substances 0.000 description 13
- 238000005259 measurement Methods 0.000 description 5
- 239000002699 waste material Substances 0.000 description 4
- YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical compound [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 description 3
- 229910052805 deuterium Inorganic materials 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000001965 increasing effect Effects 0.000 description 3
- 230000003595 spectral effect Effects 0.000 description 3
- 239000012472 biological sample Substances 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000003841 Raman measurement Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
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- 238000002372 labelling Methods 0.000 description 1
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- 230000002503 metabolic effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000011895 specific detection Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0106—General arrangement of respective parts
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/068—Optics, miscellaneous
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
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CN201710685154.2A CN107462566B (zh) | 2017-08-11 | 2017-08-11 | 用于检测特定窄波数范围的拉曼光谱仪 |
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CN107462566A CN107462566A (zh) | 2017-12-12 |
CN107462566B true CN107462566B (zh) | 2023-10-31 |
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Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109596598A (zh) * | 2019-01-07 | 2019-04-09 | 武汉大学 | 一种基于sers的便携式单波长拉曼光度计 |
DE102019114252A1 (de) * | 2019-05-28 | 2020-12-03 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren, Vorrichtung und System zum Detektieren von Raman-Streulicht |
CN110793954A (zh) * | 2019-11-05 | 2020-02-14 | 中国科学院苏州生物医学工程技术研究所 | 基于中阶梯光栅的便携式拉曼血液鉴别*** |
EP4143546A4 (en) * | 2020-04-30 | 2024-05-29 | Agency for Science, Technology and Research | FAST DIAGNOSIS FOR ANALYTE/BIOMARKER DETECTION USING RAMAN TECHNOLOGY WITH A RAMAN MEASUREMENT SYSTEM WITHOUT A SPECTROMETER |
CN111896096B (zh) * | 2020-06-30 | 2021-12-21 | 太原理工大学 | 一种利用光子计数器精确测量机械振动的装置 |
EP3961195A1 (de) * | 2020-08-28 | 2022-03-02 | Siemens Aktiengesellschaft | Messeinrichtung zur brenn- oder heizwertbestimmung eines kohlenwasserstoffhaltigen brenngases |
CN115046987B (zh) * | 2022-08-15 | 2022-12-09 | 广东大湾区空天信息研究院 | 一种时间门控拉曼光谱***及其时间同步补偿方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN205898296U (zh) * | 2016-05-11 | 2017-01-18 | 中国科学院半导体研究所 | 一种基于边带滤光片的拉曼光谱仪 |
CN106404745A (zh) * | 2016-11-24 | 2017-02-15 | 中国科学院长春光学精密机械与物理研究所 | 一种CaF2光学基底深紫外激光辐射诱导表面变化检测方法 |
CN106645093A (zh) * | 2017-03-21 | 2017-05-10 | 中国工程物理研究院材料研究所 | 一种拉曼光谱面成像设备 |
CN107014803A (zh) * | 2017-06-06 | 2017-08-04 | 中国计量大学 | 一种拉曼光谱检测装置 |
CN207300890U (zh) * | 2017-08-11 | 2018-05-01 | 上海合森生物科技有限公司 | 用于检测特定窄波数范围的拉曼光谱仪 |
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2017
- 2017-08-11 CN CN201710685154.2A patent/CN107462566B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN205898296U (zh) * | 2016-05-11 | 2017-01-18 | 中国科学院半导体研究所 | 一种基于边带滤光片的拉曼光谱仪 |
CN106404745A (zh) * | 2016-11-24 | 2017-02-15 | 中国科学院长春光学精密机械与物理研究所 | 一种CaF2光学基底深紫外激光辐射诱导表面变化检测方法 |
CN106645093A (zh) * | 2017-03-21 | 2017-05-10 | 中国工程物理研究院材料研究所 | 一种拉曼光谱面成像设备 |
CN107014803A (zh) * | 2017-06-06 | 2017-08-04 | 中国计量大学 | 一种拉曼光谱检测装置 |
CN207300890U (zh) * | 2017-08-11 | 2018-05-01 | 上海合森生物科技有限公司 | 用于检测特定窄波数范围的拉曼光谱仪 |
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