CN107462565B - Silver gyrocarpus/graphene/gold film three-dimensional SERS (surface enhanced Raman Scattering) substrate and preparation method thereof - Google Patents
Silver gyrocarpus/graphene/gold film three-dimensional SERS (surface enhanced Raman Scattering) substrate and preparation method thereof Download PDFInfo
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- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
- G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
Abstract
The invention provides a preparation method and application of a silver gyrocarpus/graphene/gold film composite three-dimensional Raman enhancement substrate, which comprises the following steps: the gold nano-film is deposited on the surface of the quartz substrate by a thermal evaporation method, graphene grown by a wet transfer Chemical Vapor Deposition (CVD) method is used, and then a silver-coated encephalic nanostructure is evaporated on the surface of the graphene by the thermal evaporation method, so that the silver-coated encephalic/graphene/gold film composite three-dimensional Raman enhanced substrate can be obtained. Repeating the steps can prepare the three-dimensional composite structure of the silver-coated Naokui/graphene/gold film on the flexible ultrathin mica sheet to obtain the flexible Raman-enhanced substrate for food safety detection.
Description
Technical Field
The invention belongs to the field of three-dimensional Raman enhancing (SERS) substrates, and particularly relates to a preparation method and application of a silver-based gyrocarpus/graphene/gold film composite three-dimensional SERS substrate.
Background
Raman enhancement, a physical phenomenon that has attracted the attention of a large number of researchers in recent years, has provided ultrasensitive and label-free chemical and biological analyses. Researchers have made many efforts to improve the enhancement intensity, sensitivity and uniformity of raman-enhanced substrates. Studies have shown that these criteria depend mainly on the number and density of hot spots generated by the action of the laser excitation of the noble metal. Compared with a two-dimensional enhanced substrate, the three-dimensional Raman enhanced substrate has larger specific surface area, so that the number of heating points can be increased, and the absorption of molecules to be detected is facilitated, so that a Raman enhanced signal with high sensitivity can be obtained. At present, a great deal of work is mainly carried out by wrapping a dielectric layer on the surface of a noble metal by using a photoetching technology, an electron beam photoetching technology and a magnetron sputtering technology which are high in cost and complex in process to realize two-dimensional or three-dimensional Raman enhancement substrate preparation, so that the mass production is limited.
Chinese patent cn201510417395.x discloses a preparation method of a G-SERS substrate and a cancer cell detection method, which are silver nanostructure-graphene-gold nanostructure devices. But the indexes of enhanced strength, sensitivity and uniformity are very susceptible to the shape, size and periodicity of the metal nanostructure. Therefore, it is urgently needed to develop a novel raman-enhanced substrate with higher sensitivity and better uniformity.
Disclosure of Invention
In order to overcome the defects, the invention provides a preparation method and application of a silver-based gyrocarpus/graphene/gold film composite three-dimensional Raman enhancement substrate. The method is simple to operate and low in cost, can realize batch preparation of the three-dimensional Raman enhancement substrate, and the obtained Raman enhancement substrate is high in sensitivity and uniformity and can be put into practical application.
In order to achieve the purpose, the invention adopts the following technical scheme:
a silver gyrocarpus/graphene/gold film composite three-dimensional Raman enhancement substrate comprises:
a graphene-gold nanostructure substrate;
a silver gyrocompartments deposited on the graphene-gold nanostructure substrate;
the silver-based gyrocembrin nanostructure is a structure body which is similar to the gyrocembrin and sulcus structure of the human cerebral cortex and is composed of nano silver.
Compared with the traditional spherical nano particles, the complex silver-based gyrolaou nano structure has more hot spots with higher density due to higher periodicity and ultra-narrow nano gaps.
Preferably, the width of the silver gyrus nanostructure is 10-30nm, the gap is 1-10nm, and the thickness is 2-10 nm.
Preferably, the substrate material is quartz, silicon or a flexible ultrathin mica sheet.
Preferably, in the graphene-gold nanostructure substrate, the thickness of the gold nano thin film is 10-50 nm.
Preferably, in the graphene-gold nanostructure substrate, the number of graphene layers is 2 to 10.
The invention also provides a manufacturing method of the silver brain wire/graphene/gold film composite three-dimensional Raman enhancement substrate, which comprises the following steps:
preparing a graphene-gold nanostructure substrate;
thermally evaporating a silver-encephalic nanostructure on a graphene-gold nanostructure substrate to obtain the silver-encephalic nanostructure;
the silver-based gyrocembrin nanostructure is a structure body which is similar to the gyrocembrin and sulcus structure of the human cerebral cortex and is composed of nano silver.
Compared with the traditional spherical nano particles, the complex silver brain-gyrus nano structure has the following advantages:
1. large specific surface area: the Raman enhancement substrate is more sensitive due to the fact that molecules to be detected are in contact with the substrate effectively;
2. ultra-narrow nanometer gap: stronger electromagnetic field enhancement is obtained under the excitation of laser;
3. the silver gyrus has high periodicity: the ultra-narrow nanometer gaps are more dense, the obtained hot spots are more dense, so that the molecules to be detected effectively fall into the dense hot spots, and the obtained enhanced signals are more uniform.
Preferably, the thermal evaporation comprises the following specific steps: putting the graphene-gold nanostructure substrate into thermal evaporation equipment, placing 0.0015g of high-purity silver wire in a molybdenum boat at a distance of 15cm, sealing, and pumping to 5 × 10-3Pa, regulating the current to 90A, and obtaining the silver gyrocell nano structure.
Preferably, the width of the silver gyrus nanostructure is 10-30nm, the gap is 1-10nm, and the thickness is 2-10 nm.
Preferably, the substrate material is quartz, silicon or a flexible ultrathin mica sheet.
Preferably, the method for preparing the graphene-gold nanostructure substrate comprises the following steps: depositing a gold nano-film on the surface of the substrate by using a thermal evaporation method, and transferring graphene grown by a Chemical Vapor Deposition (CVD) method by using a wet method;
more preferably, the thickness of the gold nano-film is 10-50nm,
more preferably, the number of the graphene layers is 2-10.
The invention also provides the silver gyrus/graphene/gold film composite three-dimensional Raman enhancement substrate prepared by any one of the methods.
The invention also provides application of the silver gyrus/graphene/gold film composite three-dimensional Raman enhancement substrate taking the flexible ultrathin mica sheet as the substrate material in food safety detection.
The invention has the advantages of
(1) Compared with the prior art, the three-dimensional Raman enhancement substrate prepared by the invention combines the gold nano-film, the double-layer graphene and the silver gyrophora nano-structure, and can give full play to the advantages of the three: the silver gyrocardia nanostructure and the gold film are separated by double-layer graphene to generate a gap of 0.68nm, so that the quantum tunneling is avoided, and simultaneously, the super-strong plasma coupling effect is generated to obtain a high-density longitudinal hot spot. The graphene has good biocompatibility, so that adsorption molecules can enter a longitudinal hot spot region, and the sensitivity of the three-dimensional SERS substrate is improved by surface plasmon polariton and local surface plasmon based on coupling of a gold film and a silver gyromagnetic nanostructure. Most importantly, the silver-containing gyrocembrin nanostructure is introduced into the invention, and a large number of gyrocembrin and sulcus of the human cerebral cortex are inspired to enable people to have various physical activities. Therefore, the specific surface area is greatly increased firstly by forming the silver gyrus nanostructure, so that more molecules are effectively adsorbed on the surface, and in addition, the silver gyrus nanostructure has high periodicity, so that dense ultra-narrow sulci is obtained, the hot spot density is improved, and the enhancement strength, the sensitivity and the uniformity of the Raman enhancement substrate are improved; in addition, the preparation method of the three-dimensional SERS substrate is non-toxic and pollution-free, is simple to operate, and can be directly prepared on a flexible ultrathin mica sheet for actual food safety detection; the key point is that the preparation of the silver-based gyrocarpus/graphene/gold film composite three-dimensional Raman enhancement substrate is realized for the first time.
(2) The preparation method is simple, high in detection efficiency, strong in practicability and easy to popularize.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this application, illustrate embodiments of the application and, together with the description, serve to explain the application and are not intended to limit the application.
Fig. 1 is a schematic diagram of a silver-coated rhodogyrum/graphene/gold film composite three-dimensional raman-enhanced substrate prepared by the method.
FIG. 2(a) is a height view of an atomic force microscope of a gold film according to the present invention;
fig. 2(b) is a raman spectrum of graphene in the present invention.
Fig. 3 is a scanning electron microscope image of the silver brain wire/graphene/gold film composite three-dimensional raman-enhanced substrate prepared by the method.
Fig. 4 is a raman enhancement spectrogram of R6G molecules obtained by preparing a compound three-dimensional raman enhancement substrate of a silvery gyrus/graphene/gold film according to the present invention: (a) 10. the method of the present invention-5-10-13Raman spectrum of R6G molecule at M concentration, (b) 10 detected at randomly selected 50 points on this SERS substrate-8Molecular raman spectrum of R6G at M concentration.
Fig. 5(a) is a photograph of a flexible silver gyrus/graphene/gold film composite three-dimensional raman-enhanced substrate prepared on a mica film according to the present invention for in situ detection of Malachite Green (MG) on the surface of shrimp skin;
fig. 5(b) is a raman-enhanced spectrogram of MG molecules detected in situ by the flexible silver-coated/graphene/gold film composite three-dimensional raman-enhanced substrate prepared in the present invention.
Detailed Description
It should be noted that the following detailed description is exemplary and is intended to provide further explanation of the disclosure. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs.
A preparation method and application of a silver gyrocarpus/graphene/gold film composite three-dimensional Raman enhancement substrate comprise the following steps: the gold nano-film is deposited on the surface of the quartz substrate by a thermal evaporation method, graphene grown by a wet transfer Chemical Vapor Deposition (CVD) method is used, and then a silver-coated encephalic nanostructure is evaporated on the surface of the graphene by the thermal evaporation method, so that the silver-coated encephalic/graphene/gold film composite three-dimensional Raman enhanced substrate can be obtained. Repeating the steps can prepare the three-dimensional composite structure of the silver-coated Naokui/graphene/gold film on the flexible ultrathin mica sheet to obtain the flexible Raman-enhanced substrate for food safety detection.
Further, the thickness of the gold nano-film is 10-50 nm.
Furthermore, the number of the graphene layers is 2-10.
Furthermore, the width of the silver gyrophora nanostructure is 10-30nm, the gap is 1-10nm, and the thickness is 2-10 nm.
Example 1
A preparation method of a silver gyrocarpus/graphene/gold film composite three-dimensional Raman enhancement substrate comprises the following preparation steps:
1) putting the quartz substrate into acetone, alcohol and deionized water in sequence, and ultrasonically cleaning for fifteen minutes in an ultrasonic machine to obtain a clean quartz substrate;
2) physical Vapor Deposition (PVD) thermal evaporation of gold films: putting the cleaned quartz piece into thermal evaporation equipment 15cm away from a molybdenum boat (length: 10cm, width: 10mm, thickness: 0.3mm), putting 0.0080g of high-purity gold wire into the molybdenum boat, sealing, and pumping to 5 × 10-3Pa, regulating the current to 130A to obtain a uniform gold film;
3) and (3) wet transfer of graphene: firstly, coating a protective layer PMMA (polymethyl methacrylate) solution on a copper foil with graphene, naturally airing, and putting the copper foil into prepared FeCl3And (1M) floating the copper foil on the surface of the solution, fishing the PMMA/graphene (graphene) into deionized water after the copper foil is completely etched, and cleaning the copper foil for 5 times by using the deionized water in order to completely clean the residual etching solution. The prepared gold film is used for slightly fishing up the graphene from the water to enable the graphene to be flatly attached to the surface of the gold film, the graphene is placed on a heating platform to be baked for 30min at the temperature of 130 ℃ after the water is completely and naturally evaporated, then in order to completely remove the PMMA protective layer, a sample is placed into hot acetone (80 ℃) to be boiled for 3 times (30 min each time), and thus graphene/Au/SiO are obtained2A composite substrate;
4) PVD thermal evaporation silver brain return nanostructure: putting the obtained sample into thermal evaporation equipment, placing 0.0015g of high-purity silver wire in a position 15cm away from a molybdenum boat, sealing, and pumping to 5 × 10-3Pa, regulating the current to 90A to obtain a silver gyrocarpus nanostructure;
5) and (3) characterization: fig. 2(a) is an atomic force microscope image of a silver gyrus/graphene/gold film three-dimensional raman enhanced substrate gold film prepared in the embodiment of the present invention, and it can be seen from fig. 2 that: (1) the thickness of the prepared uniform gold film (2) is 38 nm; fig. 2(b) is a raman spectrum of the three-dimensional raman-enhanced substrate graphene with silver gyrus/graphene/gold film prepared in the embodiment of the present invention, and it can be seen from fig. 2 (b): (1) the number of layers of the prepared high-quality graphene (2) is 2.
Fig. 3 is a scanning electron microscope image of a silver gyrus/graphene/gold film three-dimensional raman-enhanced substrate prepared in the embodiment of the present invention, and it can be seen from fig. 3 that: (1) the prepared silver nanostructure similar to the gyrophora (2) has high periodicity and ultra-narrow nanogap.
Fig. 4 is a raman enhancement spectrogram of R6G molecules obtained by preparing a silver-coated/graphene/gold film composite three-dimensional raman enhancement substrate according to the present invention, and it can be seen from fig. 4 that: the prepared three-dimensional Raman enhancement substrate is utilized to obtain the Raman enhancement spectrum of the R6G molecule with high sensitivity and high uniformity.
Example 2
A preparation method of a flexible silver gyrocarpus/graphene/gold film composite three-dimensional Raman enhancement substrate comprises the following preparation steps:
1) sequentially putting the flexible mica film into acetone, alcohol and deionized water, and ultrasonically cleaning for fifteen minutes in an ultrasonic machine to obtain a clean mica substrate;
2) physical Vapor Deposition (PVD) thermal evaporation of gold films: placing the cleaned mica sheet in a thermal evaporation device 15cm away from a molybdenum boat (length: 10cm, width: 10mm, thickness: 0.3mm), placing 0.0080g of high-purity gold wire in the molybdenum boat, sealing, and pumping to 5 × 10-3Pa, regulating the current to 130A to obtain a uniform gold film;
3) and (3) wet transfer of graphene: firstly, coating a protective layer PMMA solution on a copper foil with graphene, naturally airing, and putting the copper foil into prepared FeCl3And (1M) in the solution, enabling the copper foil to float on the surface of the solution, fishing the PMMA/graphene into deionized water after the copper foil is completely etched, and cleaning the copper foil for 5 times by using the deionized water in order to completely clean the etching solution residues. The prepared gold film is used for slightly fishing up the graphene from the water to enable the graphene to be flatly attached to the surface of the gold film, the graphene is placed on a heating platform to be baked for 30min at the temperature of 130 ℃ after the water is completely and naturally evaporated, then in order to completely remove a PMMA (polymethyl methacrylate) protective layer, a sample is placed into hot acetone (80 ℃) to be boiled for 3 times (30 min each time), and thus a graphene/Au/mica (mica) composite substrate is obtained;
4) PVD thermal evaporation silver brain return nanostructure: putting the obtained sample into thermal evaporation equipment, placing 0.0015g of high-purity silver wire in a position 15cm away from a molybdenum boat, sealing, and pumping to 5 × 10-3Pa, regulating the current to 90A to obtain a silver gyrocarpus nanostructure;
5) fig. 5 shows that the flexible silver brain loop/graphene/gold film composite three-dimensional raman-enhanced substrate prepared by the method is applied to the in-situ detection of malachite green residues on the surface of shrimp skin, and as can be seen from fig. 5, the prepared three-dimensional flexible raman-enhanced substrate is used for sensitively detecting the raman-enhanced spectrum of the MG molecule residues, so that the method can be used as a sensor label and simply and easily attached to the surface of food for food safety detection, can be produced in batches, has low cost, and can meet the requirements of practical application.
The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims (9)
1. A silver brain hair/graphene/gold film composite three-dimensional Raman-enhanced substrate is characterized by comprising:
a graphene-gold nanostructure substrate;
a silver gyrocompartments deposited on the graphene-gold nanostructure substrate;
the silver-based gyrocembrin nanostructure is a structure body which is similar to the gyrocembrin and sulcus structure of the human cerebral cortex and is formed by nano silver;
the width of the silver brain gyrus nanostructure is 10-30nm, the gap is 1-10nm, and the thickness is 2-10 nm;
the substrate material is quartz, silicon or a flexible ultrathin mica sheet;
the number of the layers of the graphene is 2-10; the silver gyrocembria nanostructure has ultra-narrow nanogap and periodicity.
2. A method for manufacturing a silver brain wire/graphene/gold film composite three-dimensional Raman enhanced substrate is characterized by comprising the following steps:
preparing a graphene-gold nanostructure substrate;
thermally evaporating a silver-encephalic nanostructure on a graphene-gold nanostructure substrate to obtain the silver-encephalic nanostructure;
the silver-based gyrocembrin nanostructure is a structure body which is similar to the gyrocembrin and sulcus structure of the human cerebral cortex and is composed of nano silver.
3. The method according to claim 2, wherein the thermal evaporation comprises the following specific steps: putting the graphene-gold nanostructure substrate into thermal evaporation equipment, placing 0.0015g of high-purity silver wire in a molybdenum boat at a distance of 15cm, sealing, and pumping to 5 × 10-3Pa, regulating the current to 90A, and obtaining the silver gyrocell nano structure.
4. The method of claim 2, wherein the silver gyrocembria nanostructures have a width of 10-30nm, a gap of 1-10nm, and a thickness of 2-10 nm.
5. The method of claim 2, wherein the substrate material is quartz, silicon, or a flexible ultra-thin mica sheet.
6. The method of claim 2, wherein the method of preparing the graphene-gold nanostructure substrate is: depositing a gold nano-film on the surface of the substrate by using a thermal evaporation method, and transferring graphene grown by a chemical vapor deposition method by a wet method.
7. The method of claim 6, wherein the gold nanofilm has a thickness of 10-50 nm.
8. The silver gyrus/graphene/gold film composite three-dimensional Raman-enhanced substrate prepared by the method according to any one of claims 2 to 7.
9. The use of the silver-coated-layer/graphene/gold-coated composite three-dimensional raman-enhanced substrate in food safety detection according to claim 1 or claim 8, wherein the substrate material of the silver-coated-layer/graphene/gold-coated composite three-dimensional raman-enhanced substrate is a flexible ultrathin mica sheet.
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| KR20200084690A (en) | 2019-01-03 | 2020-07-13 | 삼성전자주식회사 | Surface-enhanced Raman scattering patch and Raman spectroscopy system adopting the same |
| CN110554022B (en) * | 2019-09-17 | 2021-11-09 | 山东师范大学 | Double-heterostructure surface-enhanced Raman substrate for in-situ detection and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103172404A (en) * | 2013-04-05 | 2013-06-26 | 浙江理工大学 | Three-dimensional metal-graphene composite substrate and preparation method thereof |
| CN103293142A (en) * | 2013-05-09 | 2013-09-11 | 北京大学 | Flexible surface enhanced Raman spectrum base and preparation method thereof |
| CN104508466A (en) * | 2012-08-10 | 2015-04-08 | 浜松光子学株式会社 | Surface-enhanced Raman scattering element |
| CN105092556A (en) * | 2015-07-15 | 2015-11-25 | 哈尔滨工业大学深圳研究生院 | Preparation method for G-SERS (Graphene surface enhanced Raman spectra) substrate and cancer cell detection method |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102285629B (en) * | 2011-05-05 | 2014-03-26 | 厦门大学 | Preparation method for surface-enhanced Raman spectrum active substrate |
| CN103103608A (en) * | 2011-11-09 | 2013-05-15 | 中国科学院合肥物质科学研究院 | Film formed by silver nanosheets and preparation method and application of film |
| CN102545022A (en) * | 2012-01-20 | 2012-07-04 | 上海交通大学 | Saturable absorption mirror of wide band graphene |
| US9279759B2 (en) * | 2012-05-01 | 2016-03-08 | University Of Maryland, College Park | Nanoparticle array with tunable nanoparticle size and separation |
| CN104520696B (en) * | 2012-08-10 | 2018-01-12 | 浜松光子学株式会社 | SERS element and its manufacture method |
| US9068890B2 (en) * | 2013-09-18 | 2015-06-30 | Dmitry Maznichenko | Three-dimensional titania nano-fibrous architecture for molecular detection by Raman spectroscopy |
| CN104949959A (en) * | 2015-07-12 | 2015-09-30 | 北京工业大学 | Quick preparing method for large-area surface Raman spectrum enhancing monocrystalline silicon substrate |
| CN108368469A (en) * | 2015-10-07 | 2018-08-03 | 加利福尼亚大学校董会 | The multi-modal sensor of graphene system |
| CN105911044B (en) * | 2016-04-25 | 2019-02-15 | 中国科学院理化技术研究所 | A kind of Raman spectrum base and preparation method thereof with nano gap |
| CN106404738B (en) * | 2016-09-05 | 2019-12-13 | 山东师范大学 | Graphene oxide/silver nanoparticle/pyramid-shaped silicon three-dimensional Raman enhanced substrate and preparation method and application thereof |
-
2017
- 2017-07-21 CN CN201710602081.6A patent/CN107462565B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104508466A (en) * | 2012-08-10 | 2015-04-08 | 浜松光子学株式会社 | Surface-enhanced Raman scattering element |
| CN103172404A (en) * | 2013-04-05 | 2013-06-26 | 浙江理工大学 | Three-dimensional metal-graphene composite substrate and preparation method thereof |
| CN103293142A (en) * | 2013-05-09 | 2013-09-11 | 北京大学 | Flexible surface enhanced Raman spectrum base and preparation method thereof |
| CN105092556A (en) * | 2015-07-15 | 2015-11-25 | 哈尔滨工业大学深圳研究生院 | Preparation method for G-SERS (Graphene surface enhanced Raman spectra) substrate and cancer cell detection method |
Non-Patent Citations (2)
| Title |
|---|
| "Fabrication of long-range ordered, broccoli-like SERS arrays and application in detecting endocrine disrupting chemicals";Jing Chen et al.;《Journal of Materials Chemistry C》;20141203;第1309-1318页 * |
| "Surface enhanced Raman scattering of gold nanoparticles supported on copper foil with graphene as a nanometer gap";Quan Xiang et al;《Nanotechnology》;20160114(第27期);第075201（1-7）页 * |
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