CN107441392A - It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provided according to Chinese traditional treatment hyperlipidemia and the understanding mechanism of cerebral arteriovenous malformation it is a kind of treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation, each component and its mass parts ratio of the medicine are as follows：30~180g of ginseng, 50~120g of safflower, 100~260g of RADIX POLYGONI MULTIFLORI PREPARATA, 30~120g of hawthorn, 150~350g of French beans, 50~180g of barrenwort, 30~120g of folium panacis japonici cum caule, 50~120g of grass-leaved sweetflag, 30~100g of pseudo-ginseng, 150~360g of Chinese yam, 50~120g of Ligusticum wallichii, 100~360g of coix seed, 50~180g of the red sage root, 90~160g of Ramulus Taxilli, 30~100g of dried orange peel, 80~180g of the root of kudzu vine, 150~350g of cornu bubali, 100~260g of rhizoma alismatis, 2~6g of borneol；Medicine provided by the invention is a good Chinese prescription.

Description

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating hyperlipidemia and cerebral arteriovenous malformation The field of thing, the pill medicine particularly used for hyperlipidemia and cerebral arteriovenous malformation patient and preparation method thereof.

Background technology

Motherland's medical science thinks：Hyperlipidemia refers to that blood lipid level is too high, can directly cause some to seriously endanger health Disease, such as atherosclerosis, coronary heart disease, pancreatitis.

Clinical manifestation：The clinical manifestation of hyperlipidemia is mainly lipid in the caused xanthoma of intradermal deposition and lipid The caused artery sclerosis of skin deposition in the blood vessels.Although hyperlipidemia can cause xanthoma, its incidence is simultaneously not bery high；And The occurrence and development of atherosclerosis are a kind of slow progressive process again.Therefore, under normal conditions, most of patients has no Manifest symptom and abnormal sign.Many people are due to that other reasonses just find there is plasma lipoprotein water when carrying out blood biochemical inspection Flat rise.

Cerebral arteriovenous malformation is a part for systemic arteriosclerosis, while is also acute brain blood circulation especially cerebral ischemia attack Principal pathogenetic basis, be caused by various factors cerebral artery tube wall denaturation and hardening general name.Including medically usually mentioning Cerebral atherosclerosis（Artery big or middle）, arteriosclerosis, the hyalinization of small artery be referred to as cerebral arteriovenous malformation.

So, it is ability with regard to how to find a kind of Chinese medicine composition that can effectively treat hyperlipidemia and cerebral arteriovenous malformation The problem of field technique personnel are urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment hyperlipidemia and cerebral arteriovenous malformation, people gradually anticipate The advantages of having known Chinese traditional treatment hyperlipidemia and cerebral arteriovenous malformation, and good effect, quick, toxic side effect over the course for the treatment of The advantage such as small, for existing western medical treatment hyperlipidemia and the present situation of cerebral arteriovenous malformation, the purpose of the present invention is to be to provide one Kind treats hyperlipidemia and the pill medicine of cerebral arteriovenous malformation, recovers strong early to solve hyperlipidemia and cerebral arteriovenous malformation patient The problem of health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be treated State hyperlipidemia and cerebral arteriovenous malformation.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided one kind treat hyperlipidemia and Pill medicine of cerebral arteriovenous malformation and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：

30~180g of ginseng, 50~120g of safflower, 100~260g of RADIX POLYGONI MULTIFLORI PREPARATA, 30~120g of hawthorn, 150~350g of French beans, excessive sheep 50~180g of the leaves of pulse plants, 30~120g of folium panacis japonici cum caule, 50~120g of grass-leaved sweetflag, 30~100g of pseudo-ginseng, 150~360g of Chinese yam, Ligusticum wallichii 50~ 120g, 100~360g of coix seed, 50~180g of the red sage root, 90~160g of Ramulus Taxilli, 30~100g of dried orange peel, 80~180g of the root of kudzu vine, water 150~350g of ox horn, 100~260g of rhizoma alismatis, 2~6g of borneol, appropriate starch.

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation and preparation method thereof, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：

38~150g of ginseng, 58~105g of safflower, 115~230g of RADIX POLYGONI MULTIFLORI PREPARATA, 38~105g of hawthorn, 180~320g of French beans, excessive sheep 58~160g of the leaves of pulse plants, 38~105g of folium panacis japonici cum caule, 58~105g of grass-leaved sweetflag, 38~90g of pseudo-ginseng, 180~310g of Chinese yam, Ligusticum wallichii 58~ 105g, 115~310g of coix seed, 58~150g of the red sage root, 100~140g of Ramulus Taxilli, 38~90g of dried orange peel, 90~150g of the root of kudzu vine, water 180~310g of ox horn, 115~230g of rhizoma alismatis, 3~5g of borneol, appropriate starch.

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation and preparation method thereof, it is characterised in that it is described " most The each component and its mass parts of the medicine of good scheme " are than as follows：

Ginseng 130g, safflower 90g, RADIX POLYGONI MULTIFLORI PREPARATA 200g, hawthorn 95g, French beans 280g, barrenwort 140g, folium panacis japonici cum caule 95g, grass-leaved sweetflag 95g, pseudo-ginseng 80g, Chinese yam 280g, Ligusticum wallichii 95g, coix seed 280g, red sage root 130g, Ramulus Taxilli 120g, dried orange peel 80g, root of kudzu vine 130g, Cornu bubali 280g, rhizoma alismatis 200g, borneol 4g, appropriate starch.

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation and preparation method thereof, it is characterised in that the side Method comprises the following steps to be prepared：

A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With；

B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.9mm~4.0mm）, and then dry, sterilization, packing is close Envelope.

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation and preparation method thereof, it is characterised in that the clothes It is with method：By the water pill medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, and dosage 6.5g/time, meal Preceding clothes, while eat vegetables and fruit more.30 days are a course for the treatment of, and 1~5 course for the treatment of of taking medicine, symptom disappears, and disease accuses recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Ginseng, nature and flavor：Sweet slight bitter, temperature, have reinforce vital energy, prevent prolapse and engender liquid, the effect of calming the nerves, for treating, internal lesion caused by overexertion is deficient, food Less, burnout, regurgitation and emesis, stool lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, disappear Yearningly, woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, all qi-blood-body fluids deficiency；

Safflower, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation can be through, stasis-dispelling and pain-killing, for treating Amenorrhea, dysmenorrhoea, the postpartum stasis of blood The diseases such as resistance stomachache, born of the same parents' numbness pained a lump in the abdomen causing distension and pain, traumatic injury, arthralgia, middle windage yaw are completed, macula；

RADIX POLYGONI MULTIFLORI PREPARATA, nature and flavor：Bitter, sweet, puckery, slightly warm in nature, have nourishing the blood and yin, relax bowel, preventing malaria, wind-dispelling, removing toxic substances the effect of, use In treatment deficiency of blood Light-headedness, palpitaition, insomnia, the soreness and weakness of waist and knees of the deficiency of liver-yin and kidney-yin, poliosis, tinnitus, seminal emission, dry constipation of intestines, The diseases such as chronic malaria body void, rubella itch, sore carbuncle, scrofula, hemorrhoid；

Hawthorn, nature and flavor：Sour sweet, tepor, it is nontoxic, there is digestion gathered food, change the effect of stagnant stasis of blood, for Therapeutic diet to be stagnant, gastral cavity abdomen is swollen Bitterly, dysentery, dysmenorrhea due to blood stasis, amenorrhoea, postpartum abdominal pain, lochiorrhagia；

French beans, nature and flavor：It is sweet, flat, have invigorating spleen, relieve summer heat dampness elimination the effect of, for treat summer-heat and damp vomit and diarrhoea, it is insufficiency of the spleen vomit it is inverse, food It is few let out long, the disease such as water stops quenching one's thirst, leukorrhea with reddish discharge, infantile malnutrition；

Barrenwort, nature and flavor：Xin Gan, temperature, there is the effect of tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, do not lifted for treating impotence, urine leaching Drip, muscles and bones contraction urgency, hemiplegia, waist-leg weakness, arthralgia pain due to rheumatism, four limbs are meciless；

Folium panacis japonici cum caule, nature and flavor：It is sweet, bitter, cold, there is tonifying Qi, beneficial lung, driving away summer heat, the effect of promoting the production of body fluid, for treating qi-asthenia cough, hot summer weather Agitation, injury thirst, the head are unclear, the tired disease such as weary of four limbs；

Grass-leaved sweetflag, nature and flavor：Pungent, tepor, have and have one's ideas straightened out, slit phlegm, qi-regulating, promoting blood circulation, dissipate wind, the effect of drying, for treat epilepsy, Coma due to blocking of the respiratory system, pyreticosis coma, forgetful, deafness with qi stagnation, ambition unhappiness, stomachache, stomachache, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury；

Pseudo-ginseng, nature and flavor：Sweet, slight bitter, temperature, have dissipate stasis of blood hemostasis, detumescence ding-tong the effect of, for treat spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, Have blood in stool, uterine bleeding, traumatism and bleeding, chest and abdomen twinge, tumbling and swelling；

Chinese yam, nature and flavor：It is sweet, flat, have tonifying spleen, support lung, reinforce the kidney, strengthening the essence the effect of, for treat splenasthenic diarrhea, deficiency of food edema, Deficiency syndrome of the lung cough and asthma, quench one's thirst, pass out semen, with, kidney deficiency frequent micturition, the diseases such as carbuncle swells, scrofula are controlled in external application；

Ligusticum wallichii, nature and flavor：It is pungent, warm, there is the effect of wet promote breath and open depression, method wind-dryness, promoting blood circulation and stopping pain, for treating air-cooled headache rotation Dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores, irregular menstruation, lump in the abdomen stomachache, chest side of body thorn Bitterly, tumbling and swelling, arthralgia pain due to rheumatism；

Coix seed, nature and flavor：It is sweet, light, be slightly cold, have dampness removing invigorating the spleen, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus the effect of, for treat oedema, Under tinea pedis, dribbling urination, damp-warm diseases, diarrhea band, the disease such as arthralgia pain due to rheumatism, muscle arteries and veins contraction, lung carbuncle, acute appendicitis, flat wart；

The red sage root, nature and flavor：Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, lumps in the chest and abdomen, the swelling and pain of hot numbness, traumatic injury, Heat enters the diseases such as ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Ramulus Taxilli, nature and flavor：It is bitter, sweet, flat, have filling liver kidney, strengthening the bones and muscles, wind-damp dispelling, it is antiabortive first the effect of, for treating rheumatism numbness Bitterly, the illness such as soreness and weakness of waist and knees, muscles and bones is powerless, uterine bleeding warp is more, blood leaking in gestation, fetal irritability, hypertension；

Dried orange peel, nature and flavor：It is bitter, pungent, warm, have regulating qi-flowing for strengthening spleen, it is eliminating dampness and eliminating phlegm the effect of, for treat chest gastral cavity turgor, deficiency of food vomit and diarrhoea, Coughing with a lot of sputum；

The root of kudzu vine, nature and flavor：It is sweet, pungent, flat, have expelling pathogenic factors from muscles and skin bring down a fever, deliver examine, promote the production of body fluid to quench thirst, Shengyang Zhixie the effect of, for treating Fever caused by exogenous pathogens, rigidity of nape and headache, measles go out that not smooth, warm disease is thirsty, diabete, diarrhea, dysentery, hypertension, coronary heart disease from the beginning of, rash；

Cornu bubali, nature and flavor：It is bitter, cold, have clearing heat and detoxicating, cool blood, arresting convulsion the effect of, for treat warm disease high fever, coma and delirium, The illness such as spot dermexanthesis, hematemesis and epistaxis, infantile convulsion, demented；

Rhizoma alismatis, nature and flavor：It is sweet, light, cold in nature, there is clearing damp and promoting diuresis, expel the heat-evil the effect for the treatment of stranguria, for treating difficult urination, heat gonorrhea The diseases such as puckery pain, oedema turgor, diarrhea, phlegmatic vertigo, seminal emission；

Borneol, nature and flavor：It is pungent, bitter, be slightly cold, have inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain the effect of, for treating pyreticosis coma, convulsion is fainted, in Wind phlegm is fainted, bstruction of the circulation of vital energy is fainted cruelly, middle evil is gone into a coma, hot eyes, aphtha, abscess of throat, duct are suppurated.

Medicine of the present invention is the principle based on Chinese traditional treatment hyperlipidemia and cerebral arteriovenous malformation, from according to hyperlipidemia and brain The pathomechanism of artery sclerosis and pharmacological action are thought：With regard to hyperlipidemia and cerebral arteriovenous malformation, in medicine provided by the present invention Each raw material herbal medicine efficacy play altogether, have good therapeutic effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned hyperlipidemia and cerebral arteriovenous malformation, use Medicine effect prepared by the formula is good, quick, is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.Below It is described in further detail with reference to the embodiment of the present invention：

Embodiment 1：

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Ginseng 130g, safflower 90g, RADIX POLYGONI MULTIFLORI PREPARATA 200g, hawthorn 95g, French beans 280g, barrenwort 140g, folium panacis japonici cum caule 95g, grass-leaved sweetflag 95g, pseudo-ginseng 80g, Chinese yam 280g, Ligusticum wallichii 95g, coix seed 280g, red sage root 130g, Ramulus Taxilli 120g, dried orange peel 80g, root of kudzu vine 130g, Cornu bubali 280g, rhizoma alismatis 200g, borneol 4g, appropriate starch.

Embodiment 2：

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Ginseng 150g, safflower 105g, RADIX POLYGONI MULTIFLORI PREPARATA 230g, hawthorn 105g, French beans 320g, barrenwort 160g, folium panacis japonici cum caule 105g, stone Chang Pu 105g, pseudo-ginseng 90g, Chinese yam 310g, Ligusticum wallichii 105g, coix seed 310g, red sage root 150g, Ramulus Taxilli 140g, dried orange peel 90g, the root of kudzu vine 150g, cornu bubali 310g, rhizoma alismatis 230g, borneol 5g, appropriate starch.

Embodiment 3：

It is a kind of to treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Ginseng 180g, safflower 120g, RADIX POLYGONI MULTIFLORI PREPARATA 260g, hawthorn 120g, French beans 350g, barrenwort 180g, folium panacis japonici cum caule 120g, stone Chang Pu 120g, pseudo-ginseng 100g, Chinese yam 360g, Ligusticum wallichii 120g, coix seed 360g, red sage root 180g, Ramulus Taxilli 160g, dried orange peel 100g, Pueraria lobota Root 180g, cornu bubali 350g, rhizoma alismatis 260g, borneol 6g, appropriate starch.

Model case

Through clinical conditions hyperlipidemia and cerebral arteriovenous malformation patient totally 1000, the age is 550 of more than 58 years old, only 450 are less than 58 years old.750 to be fully recovered in 1000 patients, effective 150, invalid 100.Total effective rate is up to 90%.

Claims (3)

1. a kind of treat hyperlipidemia and the pill medicine of cerebral arteriovenous malformation, it is characterised in that each component of the medicine and Its mass parts is than as follows：

30~180g of ginseng, 50~120g of safflower, 100~260g of RADIX POLYGONI MULTIFLORI PREPARATA, 30~120g of hawthorn, 150~350g of French beans, excessive sheep 50~180g of the leaves of pulse plants, 30~120g of folium panacis japonici cum caule, 50~120g of grass-leaved sweetflag, 30~100g of pseudo-ginseng, 150~360g of Chinese yam, Ligusticum wallichii 50~ 120g, 100~360g of coix seed, 50~180g of the red sage root, 90~160g of Ramulus Taxilli, 30~100g of dried orange peel, 80~180g of the root of kudzu vine, water 150~350g of ox horn, 100~260g of rhizoma alismatis, 2~6g of borneol, appropriate starch.

2. treatment hyperlipidemia according to claim 1 and the pill medicine of cerebral arteriovenous malformation, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：

38~150g of ginseng, 58~105g of safflower, 115~230g of RADIX POLYGONI MULTIFLORI PREPARATA, 38~105g of hawthorn, 180~320g of French beans, excessive sheep 58~160g of the leaves of pulse plants, 38~105g of folium panacis japonici cum caule, 58~105g of grass-leaved sweetflag, 38~90g of pseudo-ginseng, 180~310g of Chinese yam, Ligusticum wallichii 58~ 105g, 115~310g of coix seed, 58~150g of the red sage root, 100~140g of Ramulus Taxilli, 38~90g of dried orange peel, 90~150g of the root of kudzu vine, water 180~310g of ox horn, 115~230g of rhizoma alismatis, 3~5g of borneol, appropriate starch.

3. the pill medicine of the treatment hyperlipidemia and cerebral arteriovenous malformation according to claim 1 to 2, it is characterised in that institute The each component and its mass parts of medicine are stated than as follows：

Ginseng 130g, safflower 90g, RADIX POLYGONI MULTIFLORI PREPARATA 200g, hawthorn 95g, French beans 280g, barrenwort 140g, folium panacis japonici cum caule 95g, grass-leaved sweetflag 95g, pseudo-ginseng 80g, Chinese yam 280g, Ligusticum wallichii 95g, coix seed 280g, red sage root 130g, Ramulus Taxilli 120g, dried orange peel 80g, root of kudzu vine 130g, Cornu bubali 280g, rhizoma alismatis 200g, borneol 4g, appropriate starch.