CN107439823A - A kind of pet food that can effectively prevent canine parvovirus - Google Patents

A kind of pet food that can effectively prevent canine parvovirus Download PDF

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Publication number
CN107439823A
CN107439823A CN201710798440.XA CN201710798440A CN107439823A CN 107439823 A CN107439823 A CN 107439823A CN 201710798440 A CN201710798440 A CN 201710798440A CN 107439823 A CN107439823 A CN 107439823A
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percentage
weight
extract
pet food
effectively prevent
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邹礼兰
邹军华
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
    • C12Y101/03004—Glucose oxidase (1.1.3.4)

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  • Alternative & Traditional Medicine (AREA)
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Abstract

The present invention relates to pet food technical field, specifically, is related to a kind of pet food that can effectively prevent canine parvovirus.It is that following component forms by percentage by weight：Percentage by weight is 65% basic dog grain；Percentage by weight is 5% coptis root extract；Percentage by weight is 3% Geranium extract；Percentage by weight is 7% Radix Pulsatillae extract；Percentage by weight is 5% charred RADIX ET RHIZOMA RHEI；Percentage by weight is 10% bacillus subtilis；And the glucose oxidase that percentage by weight is 5%.The present invention preferably can prevent the parvovirus of canine.

Description

A kind of pet food that can effectively prevent canine parvovirus
Technical field
The present invention relates to pet food technical field, specifically, being related to a kind of can effectively prevent doting on for canine parvovirus Thing food.
Background technology
Canine parvovirus（CPV）It is Australian Kelly in 1978 and Canadian Thomson etc. simultaneously from suffering from enteritis Sick dog excrement in separation obtain, from the virus is found so far, there is prevalence all over the world, be endanger canine most important One of deadly infectious disease.Thereafter, the state such as the U.S., Britain, Germany, France, Italy, Russia and Japan is also found that this in succession Virus.Serosurvey shows that CPV positive serums can trace back to 1974-1976 earliest in Europe；The U.S., Canada, Japan and Australia can trace back to 1978.
Canine parvovirus occurs without obvious seasonality, general summer, autumn seasonal prevalence.Cold weather, temperature cataclysm, is defended Carded sliver part difference and accompanying infection can aggravate the state of an illness and improve the death rate.The sick 3-5 days incubation period, mostly occur behind firm ring change border （Such as the pup newly bought）, have a bath, overfeeding is inducement.The disease is most to be presented enteritis syndrome, and myocarditis syndrome is presented in minority.Intestines Scorching sick spirit at dog initial stage is depressed, apocleisis, accidental heating, soft stool or slight vomiting, then develops into frequently vomiting and violent abdomen Rush down.Originally excrement gray, yellow or milky, the soy sauce sample or tomato juice sample blood of band g., jelly-like mucus, thereafter discharge stench Just.Sick dog rapid dehydration, becomes thin, and proscopiny, hair is in disorder, and skin is nonelastic, ear nose, coolness of extremities, and spirit is highly depressed, Shock, it is dead.Pathogenic factor is not also single, it may be possible to stress cause be also likely to be bacterium, virus infection cause, or mould poison Element etc. causes, and is that mixing reason causes under normal circumstances, and single medicine can not solve these problems.
Applicant has found that canine parvovirus disease case accounts for dog disease ratio up to more than 40% after visiting Duo Jia pet clinics.Mesh Preceding prevention canine parvovirus is in dog 10-12 week old（Epidemic-stricken area is 6-8 week old by the dog of serious threat）Vaccinate first, every Injected again every 20 days 2 times, it is later annual.Due to maternal antibody interference and the reasons such as pup autoimmunity is low, vaccine Protective rate is often less than 80%.
The content of the invention
Present disclosure is to provide a kind of pet food that can effectively prevent canine parvovirus, and it can overcome existing skill Certain or some defects of art.
According to a kind of pet food that can effectively prevent canine parvovirus of the present invention, it is following by percentage by weight Component forms：
Percentage by weight is 65% basic dog grain；
Percentage by weight is 5% coptis root extract；
Percentage by weight is 3% Geranium extract；
Percentage by weight is 7% Radix Pulsatillae extract；
Percentage by weight is 5% charred RADIX ET RHIZOMA RHEI；
Percentage by weight is 10% bacillus subtilis；And
Percentage by weight is 5% glucose oxidase.
Coptis extract main component in the present invention contains jamaicin, and primary efficacy is heat-clearing and damp-drying drug, purging intense heat and detonicating. Acted on anti-vomiting, coptis extract is to hemolytic streptococcus, meningococcus, Diplococcus pneumopniae, comma bacillus, charcoal Subcutaneous ulcer bacillus and staphylococcus aureus all have stronger bacteriostasis；Have to shigella dysenteriae, corynebacterium diphtheriae, viridans streptococci Inhibitory action.The main component tannin containing geranium wilfordii of Geranium extract and Hyperoside, Kaempferol, Quercetin, protocatechuic acid, Gallic acid, Kaempferol -7- alpha-L-rhamnosides and Kaempferitrin etc..Geranium wilfordii has a broad antifungal spectrum, its flavonoids is to a variety of bacillus, gold Staphylococcus aureus, beta streptococcus, streptococcus pneumonia, micrococcus catarrhalis have obvious inhibitory action.Geranium wilfordii it is water-soluble Property extract has anti-diarrhea effect, and the activity to duodenum and small intestine has inhibitory action, and promotes the anastalsis of caecum.Old stork The energy anti-lipid peroxidation such as tannin and its catabolite corilagin in careless extract, there is anti-oxidant and anti-inflammatory to make With.
Radix Pulsatillae extract main component is protoanemonin and Anemonin.It is clearing heat and detoxicating with having, remove heat from the blood and relieve diarrhea, it is right Various bacteria has significant inhibitory action.Have to pathogenic entero becterias such as various shigella dysenteriaes and significantly suppress effect, in this product Doctor's tradition is to treat the key medicine of dysentery, including acute bacillary dysentery, amoebic dysentery and chordapsus.It can also be used for ulcerative colitis Inflammation, intestinal cancer, which is defecated, the disease of purulence blood.
Rheum officinale has very strong anti-infectious function, antioxidation, can adjust immune, anti-inflammatory, refrigeration function, disease-resistant original Microbial action, reducing blood lipid, anastalsis, anti-gastric and duodenal ulcer, promote pancreatic secretion, suppress enzymatic activity, cholagogic, Liver protection, discharge function.
Bacillus subtilis can reduce harmful microbe quantity in enteron aisle, while improve the quantity of beneficial bacteria of intestinal tract. Bacillus subtilis is aerobic bacteria, needs to consume substantial amounts of oxygen in growth course, and the environmental benefits are in lactic acid bacteria, bifid bar The growth of the anaerobic bacterias such as bacterium, suppress the breeding of aerobic enterobacteria, so as to reduce the generation of disease of digestive tract.Bacillus subtilis is also Some antibacterial substances can be produced, some pathogens are risen with antagonism, and then adjust intestinal microecology balance.It is to aerogenesis pod Film clostridium has obvious antagonism, and the growth to clostridium difficile, streptococcus pneumonia, campylobacter jejuni and Campylobacter spp has suppression Effect.The intake of bacillus can stimulating animal immune system, lymphoid tissue is in highly reactive state.
Glucose oxidase can play a part of improving intestinal environment, and cultivated animals can be made to increase appetite, be a kind of natural Probiotic.Glucose oxidase also has extraordinary detoxification ability to mycetism, can play and decompose mycotoxin Effect.
Bacillus subtilis, glucose oxidase, coptis root extract, Radix Pulsatillae extract, Geranium extract and rheum officinale Active component in charcoal, this several material have synergy well, have sterilization stop dysentery, solution mycotoxin, repair stomach and intestine Road, adjust gastrointestinal bacterial flora and can preferably promote dog intestinal wall immune cell growth, and then can effectively lift dog intestines Road immunity.And using pet food of the invention to being found after a variety of a plurality of canines progress administering transgenics, it can be preferable Ground lifts the activity of canine intestinal wall phagocyte, so as to preferably improve dog enteron aisle non-specific immunity, and then can Effectively prevent the generation of canine parvovirus.
Preferably, coptis root extract is 10：1 coptis root ratio extract.So as to which preventive effect is more notable.
Preferably, Geranium extract is 10：1 geranium wilfordii ratio extract.So as to which preventive effect is more notable.
Preferably, Radix Pulsatillae extract is 10：1 Chinese bulbul ratio extract.So as to which preventive effect is more notable.
Preferably, bacillus subtilis uses the bacillus subtilis of 10,000,000,000/gram.So as to which preventive effect is more aobvious Write.
Preferably, glucose oxidase uses the glucose oxidase of 1,000,000 units/grams.So as to preventive effect more Significantly.
Embodiment
To further appreciate that present disclosure, the present invention is described in detail in conjunction with the embodiments.It is it should be appreciated that real Apply example be only the present invention is explained and and it is non-limiting.
Embodiment 1
A kind of pet food that can effectively prevent canine parvovirus is present embodiments provided, it is following group by percentage by weight It is grouped into：
Percentage by weight is 65% basic dog grain；
Percentage by weight is 5% coptis root extract；
Percentage by weight is 3% Geranium extract；
Percentage by weight is 7% Radix Pulsatillae extract；
Percentage by weight is 5% charred RADIX ET RHIZOMA RHEI；
Percentage by weight is 10% bacillus subtilis；And
Percentage by weight is 5% glucose oxidase.
In the present embodiment, coptis root extract is 10：1 coptis root ratio extract.
In the present embodiment, Geranium extract 10：1 geranium wilfordii ratio extract.
In the present embodiment, Radix Pulsatillae extract 10：1 Chinese bulbul ratio extract.
In the present embodiment, bacillus subtilis uses the bacillus subtilis of 10,000,000,000/gram.
In the present embodiment, glucose oxidase uses the glucose oxidase of 1,000,000 units/grams.
To verify the pet food of the present embodiment, the ad hoc following experiment of meter.In the experiment, 12 healthy adult Thailand enlightening are chosen Dog, two groups are randomly divided into, control group and experimental group, control group are fed by basic grain, and experimental group feeds the pet food of the present embodiment Product；After feeding 4 weeks, control group and experimental group, which respectively introduce one, to be made a definite diagnosis the adult Thailand enlightening dog for suffering from parvovirus and is mixed into and contact one week, Observe two groups of dog incidences.Experimental result such as following table one.
Table one：
Conclusion：By upper table it can be found that the pet food of the present embodiment can effectively prevent the hair of safe enlightening dog canine parvovirus It is raw.
Embodiment two：12 healthy adult Sa Moye are chosen, are randomly divided into two groups, control group and experimental group, control group press basis Grain is fed, and experimental group feeds the pet food of the present embodiment；After feeding 4 weeks, control group respectively introduces one with experimental group and makes a definite diagnosis trouble The Sa Moye dogs of parvovirus are mixed into contact one week, observe two groups of dog incidences.Experimental result such as following table two.
Table two：
Conclusion：By upper table it can be found that the pet food of the present embodiment can effectively prevent Sa Moye canine parvovirus of growing up Generation.
Real embodiment three：Choose 12 healthy adults and draw Prado, be randomly divided into two groups, control group and experimental group, control group are pressed Basic grain feeding, experimental group feed the pet food of the present embodiment；After feeding 4 weeks, control group respectively introduces one with experimental group really Examine the drawing Prado dog for suffering from parvovirus and be mixed into contact one week, observe two groups of dog incidences.Experimental result such as following table three.
Table three：
Conclusion：By upper table it can be found that the pet food of the present embodiment can effectively prevent to draw Prado canine parvovirus Occur.
Example IV：12 healthy adult Ha Shiqi are chosen, are randomly divided into two groups, control group and experimental group, control group press basis Grain is fed, and experimental group feeds the pet food of the present embodiment；After feeding 4 weeks, control group respectively introduces one with experimental group and makes a definite diagnosis trouble The Ha Shiqi dogs of parvovirus are mixed into contact one week, observe two groups of dog incidences.Experimental result such as following table four.
Table four：
By upper table it can be found that the pet food of the present embodiment can effectively prevent the generation of Ha Shiqi canine parvovirus.
Embodiment five：The golden hair at 12 monthly ages of health 1 is chosen, is randomly divided into two groups, control group and experimental group, control group press basis Grain is fed, and experimental group feeds the pet food of the present embodiment；After feeding 4 weeks, control group respectively introduces one with experimental group and makes a definite diagnosis trouble The Cibotium barometz (L.) J. Sm of parvovirus is mixed into contact one week, observes two groups of dog incidences.Experimental result such as following table five.
Table five：
Conclusion：By upper table it can be found that the pet food of the present embodiment can improve the immunity of young age gold hair, preventing canine is tiny The generation of virus.
The present invention and embodiments thereof are described above exemplarily, the description is not restricted.So if ability The those of ordinary skill in domain is enlightened by it, without departing from the spirit of the invention, without creatively design with The technical scheme similar scheme and embodiment, all should belong to protection scope of the present invention.

Claims (6)

1. a kind of pet food that can effectively prevent canine parvovirus, it is that following component forms by percentage by weight：
Percentage by weight is 65% basic dog grain；
Percentage by weight is 5% coptis root extract；
Percentage by weight is 3% Geranium extract；
Percentage by weight is 7% Radix Pulsatillae extract；
Percentage by weight is 5% charred RADIX ET RHIZOMA RHEI；
Percentage by weight is 10% bacillus subtilis；And
Percentage by weight is 5% glucose oxidase.
A kind of 2. pet food that can effectively prevent canine parvovirus according to claim 1, it is characterised in that：Coptis root carries It is 10 to take thing：1 coptis root ratio extract.
A kind of 3. pet food that can effectively prevent canine parvovirus according to claim 1, it is characterised in that：Geranium wilfordii Extract is 10：1 geranium wilfordii ratio extract.
A kind of 4. pet food that can effectively prevent canine parvovirus according to claim 1, it is characterised in that：The Chinese bulbul Extract is 10：1 Chinese bulbul ratio extract.
A kind of 5. pet food that can effectively prevent canine parvovirus according to claim 1, it is characterised in that：Withered grass bud Spore bacillus uses the bacillus subtilis of 10,000,000,000/gram.
A kind of 6. pet food that can effectively prevent canine parvovirus according to claim 1, it is characterised in that：Glucose Oxidizing ferment uses the glucose oxidase of 1,000,000 units/grams.
CN201710798440.XA 2017-09-07 2017-09-07 A kind of pet food that can effectively prevent canine parvovirus Pending CN107439823A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101564524A (en) * 2009-06-05 2009-10-28 中国人民解放军军事医学科学院军事兽医研究所 Traditional Chinese medicine injection for treating canine parvovirus disease and preparation method thereof
CN103446271A (en) * 2013-08-07 2013-12-18 镇江天和生物技术有限公司 Compound traditional Chinese medicine extracting solution for controlling bacterial diarrhea of dog and preparation method of compound traditional Chinese medicine extracting solution
US20160303226A1 (en) * 2013-11-25 2016-10-20 Nestec S.A. Heat-treated formulation of bifidobacterium lactis ncc 2818 reduces allergic manifestations
CN106720954A (en) * 2016-12-27 2017-05-31 山东海创工贸有限公司 A kind of crystal transparent pet meat snacks and its production method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101564524A (en) * 2009-06-05 2009-10-28 中国人民解放军军事医学科学院军事兽医研究所 Traditional Chinese medicine injection for treating canine parvovirus disease and preparation method thereof
CN103446271A (en) * 2013-08-07 2013-12-18 镇江天和生物技术有限公司 Compound traditional Chinese medicine extracting solution for controlling bacterial diarrhea of dog and preparation method of compound traditional Chinese medicine extracting solution
US20160303226A1 (en) * 2013-11-25 2016-10-20 Nestec S.A. Heat-treated formulation of bifidobacterium lactis ncc 2818 reduces allergic manifestations
CN106720954A (en) * 2016-12-27 2017-05-31 山东海创工贸有限公司 A kind of crystal transparent pet meat snacks and its production method

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