CN107422664A - UV, PH based on protein chromatography system, conductance comprehensive detection system - Google Patents
UV, PH based on protein chromatography system, conductance comprehensive detection system Download PDFInfo
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- CN107422664A CN107422664A CN201710421808.0A CN201710421808A CN107422664A CN 107422664 A CN107422664 A CN 107422664A CN 201710421808 A CN201710421808 A CN 201710421808A CN 107422664 A CN107422664 A CN 107422664A
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- 238000001514 detection method Methods 0.000 title claims abstract description 39
- 238000004587 chromatography analysis Methods 0.000 title claims abstract description 18
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 15
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 15
- 238000004891 communication Methods 0.000 claims abstract description 11
- 238000000825 ultraviolet detection Methods 0.000 claims abstract description 6
- 238000006243 chemical reaction Methods 0.000 claims description 3
- 230000010354 integration Effects 0.000 abstract description 2
- 241001269238 Data Species 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- 238000005377 adsorption chromatography Methods 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000005416 organic matter Substances 0.000 description 1
- 238000004810 partition chromatography Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000004304 visual acuity Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
- G05B19/042—Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
- G05B19/0423—Input/output
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B2219/00—Program-control systems
- G05B2219/20—Pc systems
- G05B2219/24—Pc safety
- G05B2219/24215—Scada supervisory control and data acquisition
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Automation & Control Theory (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Abstract
The present invention relates to technical field of bioengineering,Specifically,It is a kind of UV based on protein chromatography system,PH,Conductance comprehensive detection system,Including MCU Main Processing Unit,Show operation module,Detection module,Power module and communication module,MCU Main Processing Unit is connected to display operation module by data wire,Detection module,Power module and communication module,Display operation module includes coder module and display screen,Detection module includes PH and detects and check and approve module,UV detection modules,Electrical conductivity detects and checked and approved module and temperature sensor module,Power module provides electric power support for whole system and uses alternating current or direct current,Connected mode of the communication module between operator and whole system,Including radio connection or wired connection mode,The present invention can detect UV simultaneously,PH and electrical conductivity,Degree of integration is high,Greatly reduce detection time,Improve operating efficiency.
Description
Technical field
The present invention relates to technical field of bioengineering, is a kind of UV, PH based on protein chromatography system, electricity specifically
Lead comprehensive detection system.
Background technology
Chromatography（chromatography）It is the abbreviation of " chromatographic analysis ".To be more using the difference of each component physical property
Component mixture is separated and method for measuring.There is two kinds of adsorption chromatography, Partition Chromatography.It is generally used for organic compound, gold
Belong to the analysis of ion, amino acid etc..Chromatography reaches separation using material allocation proportion different between stationary phase and mobile phase
The technology of purpose.Chromatographing the separation analysis to the mixture of the complicated organic matter such as large biological molecule such as protein and nucleic acid has pole
High resolving power.
In field of biological pharmacy, UV, PH, electrical conductivity detection already turn into essential link, and UV detections can be fast
Speed, the molecular structure for determining albumen exactly.PH is the yardstick for weighing solution acid-basicity, needs solution in solution preparation etc.
The measure of pH value.Electrical conductivity is then the ability of solution conduction electric current numerically, and the measure of electrical conductivity is generally used for certainly
In the higher purging system of dynamicization degree.Protein chromatography system is mostly UV, PH, conductance independent detection system currently on the market
System, or be only capable of detecting wherein two item datas, it is difficult to realize the need for detecting UV, PH and the item data of electrical conductivity three more simultaneously
Ask.
The content of the invention
Based on above-mentioned technical problem, the present invention discloses a kind of UV, PH based on protein chromatography system, conductance comprehensive detection
System, it can be used for detecting UV, PH and electrical conductivity simultaneously.
The concrete technical scheme that the present invention uses is as follows：
A kind of UV, PH based on protein chromatography system, conductance comprehensive detection system, including MCU Main Processing Unit, display operation mould
Block, detection module, power module and communication module, MCU Main Processing Unit are connected to display operation module, detection mould by data wire
Block, power module and communication module, display operation module include coder module and display screen, detection module include PH detections and
Check and approve module, UV detection modules, electrical conductivity detection and approval module and temperature sensor module, power module carry for whole system
Alternating current or direct current, connected mode of the communication module between operator and whole system, including nothing are used for electric power support
Line connected mode or wired connection mode.
Further improvement of the present invention, in addition to single-chip microcomputer, single-chip microcomputer are delivered to MCU master controls for directly reading UV signals
Unit.
Further improvement of the present invention, in addition to amplifying circuit and filter circuit, amplifying circuit and filter circuit are arranged on
PH is detected and checked and approved between module and single-chip microcomputer, and PH signals are connected to single-chip microcomputer after differential amplifier circuit and filter circuit,
Signal is delivered to MCU Main Processing Unit by single-chip microcomputer again.
Further improvement of the present invention, in addition to A/D change-over circuits, A/D change-over circuits are arranged on electrical conductivity detection and core
Between quasi-mode block and single-chip microcomputer, conductivity signal is connected to single-chip microcomputer after A/D analog-to-digital conversions, and single-chip microcomputer again conveys signal
To MCU Main Processing Unit.
Further improvement of the present invention, show that the display screen in operation module shows display screen using OLED.
Beneficial effects of the present invention：It is mostly UV, PH, conductance independent detection system relative to traditional protein chromatography system
System, or be only capable of detecting wherein two item datas, the comprehensive detection system of present disclosure can detect UV, PH and electrical conductivity simultaneously,
Degree of integration is high, greatly reduces detection time, improves operating efficiency.
Brief description of the drawings
Fig. 1 is the structural representation of the present invention.
Embodiment
In order to deepen the understanding of the present invention, the present invention is done below in conjunction with drawings and examples and further retouched in detail
State, the embodiment is only used for explaining the present invention, and protection scope of the present invention is not formed and limited.
Embodiment：As shown in figure 1, a kind of UV, PH based on protein chromatography system, electrical conductivity comprehensive detection system, including
MCU Main Processing Unit, A/D change-over circuits, power module, coder module, OLED display module, communication module, temperature detection mould
Block, UV detection modules, PH detections and calibration module, electrical conductivity detection and calibration module.Detecting system is essentially characterized in that MCU master
Control unit connects temperature detecting module, UV detection modules, PH detections and calibration module, electrical conductivity detection and calibration module
Come, and related data can be carried out by OLED display module, coder module, communication module and show and operate.Wherein, UV
Signal can be directly read by single-chip microcomputer, and PH signals are connected to single-chip microcomputer, electrical conductivity after differential amplifier circuit and filter circuit
Signal is connected to single-chip microcomputer after A/D analog-to-digital conversions.
General principle, the main features and advantages of the present invention have been shown and described above.The technical staff of the industry should
Understand, the present invention is not limited to the above embodiments, the original for simply illustrating the present invention described in above-described embodiment and specification
Reason, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes and improvements
It all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by appended claims and its equivalent circle
It is fixed.
Claims (5)
1. a kind of UV, PH based on protein chromatography system, conductance comprehensive detection system, it is characterised in that including MCU master control lists
Member, display operation module, detection module, power module and communication module, the MCU Main Processing Unit are connected to institute by data wire
Display operation module, detection module, power module and communication module are stated, the display operation module includes coder module and shown
Display screen, the detection module includes PH detections and approval module, UV detection modules, electrical conductivity detection and approval module and temperature passes
Sensor module, the power module provide electric power support for whole system and use alternating current or direct current, and the communication module is
Connected mode between operator and whole system, including radio connection or wired connection mode.
2. UV, PH according to claim 1 based on protein chromatography system, conductance comprehensive detection system, it is characterised in that
Also include single-chip microcomputer, the single-chip microcomputer is delivered to the MCU Main Processing Unit for directly reading UV signals.
3. UV, PH according to claim 2 based on protein chromatography system, conductance comprehensive detection system, it is characterised in that
Also include amplifying circuit and filter circuit, the amplifying circuit and filter circuit are arranged on the PH detections and check and approve module and institute
Between stating single-chip microcomputer, PH signals are connected to single-chip microcomputer after differential amplifier circuit and filter circuit, and the single-chip microcomputer again will letter
Number it is delivered to the MCU Main Processing Unit.
4. UV, PH, the conductance comprehensive detection system according to claim 3 in protein chromatography system, it is characterised in that also
Including A/D change-over circuits, the A/D change-over circuits be arranged on electrical conductivity detection and check and approve module and the single-chip microcomputer it
Between, conductivity signal is connected to single-chip microcomputer after A/D analog-to-digital conversions, and signal is delivered to the MCU master by the single-chip microcomputer again
Control unit.
5. UV, PH in protein chromatography system, conductance comprehensive detection system according to claim any one of 1-4, it is special
Sign is that the display screen in the display operation module shows display screen using OLED.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710421808.0A CN107422664A (en) | 2017-06-07 | 2017-06-07 | UV, PH based on protein chromatography system, conductance comprehensive detection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710421808.0A CN107422664A (en) | 2017-06-07 | 2017-06-07 | UV, PH based on protein chromatography system, conductance comprehensive detection system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107422664A true CN107422664A (en) | 2017-12-01 |
Family
ID=60429085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710421808.0A Pending CN107422664A (en) | 2017-06-07 | 2017-06-07 | UV, PH based on protein chromatography system, conductance comprehensive detection system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108279625A (en) * | 2017-12-30 | 2018-07-13 | 利穗科技(苏州)有限公司 | Digitize tomographic system and method |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258885A (en) * | 2011-05-18 | 2011-11-30 | 中国地质大学（武汉） | Automatic separation system for integrated column chromatography |
| CN202900607U (en) * | 2012-10-30 | 2013-04-24 | 荣捷生物工程（苏州）有限公司 | Intelligent biological pump controller |
| CN105784957A (en) * | 2016-04-28 | 2016-07-20 | 无锡昊瑜节能环保设备有限公司 | Industrial water quality multi-parameter monitoring system |
| CN105823860A (en) * | 2016-04-11 | 2016-08-03 | 南京鱼博士智能科技有限公司 | Special water quality multi-parameter sensor for aquaculture |
| CN206788617U (en) * | 2017-06-07 | 2017-12-22 | 利穗科技(苏州)有限公司 | UV, PH based on protein chromatography system, conductance comprehensive detection system |
-
2017
- 2017-06-07 CN CN201710421808.0A patent/CN107422664A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102258885A (en) * | 2011-05-18 | 2011-11-30 | 中国地质大学（武汉） | Automatic separation system for integrated column chromatography |
| CN202900607U (en) * | 2012-10-30 | 2013-04-24 | 荣捷生物工程（苏州）有限公司 | Intelligent biological pump controller |
| CN105823860A (en) * | 2016-04-11 | 2016-08-03 | 南京鱼博士智能科技有限公司 | Special water quality multi-parameter sensor for aquaculture |
| CN105784957A (en) * | 2016-04-28 | 2016-07-20 | 无锡昊瑜节能环保设备有限公司 | Industrial water quality multi-parameter monitoring system |
| CN206788617U (en) * | 2017-06-07 | 2017-12-22 | 利穗科技(苏州)有限公司 | UV, PH based on protein chromatography system, conductance comprehensive detection system |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108279625A (en) * | 2017-12-30 | 2018-07-13 | 利穗科技(苏州)有限公司 | Digitize tomographic system and method |
| CN108279625B (en) * | 2017-12-30 | 2023-09-05 | 利穗科技(苏州)有限公司 | Digital chromatography system and method |
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| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication | ||
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Application publication date: 20171201 |