CN107389960B - A kind of analyzer disc type reaction unit - Google Patents
A kind of analyzer disc type reaction unit Download PDFInfo
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- CN107389960B CN107389960B CN201710498779.8A CN201710498779A CN107389960B CN 107389960 B CN107389960 B CN 107389960B CN 201710498779 A CN201710498779 A CN 201710498779A CN 107389960 B CN107389960 B CN 107389960B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00207—Handling bulk quantities of analyte
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- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
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Abstract
The present invention relates to a kind of disc type reaction units, comprising: reaction disc mechanism and uniform shaking mechanism；React disc mechanism, including cylinder, the disk being rotatably arranged in cylinder；Uniform shaking mechanism；Feed mechanism and cutting agency are located at cylinder side；Heating mechanism；There are two uniform shaking mechanisms, the arc length distance of one of uniform shaking mechanism to feed mechanism is 1/3-1/4 circle, the arc length distance of two uniform shaking mechanisms is 2/3-3/4 circle, second uniform shaking mechanism to cutting agency distance at a distance of a distance for reaction cup receiving hole, feed mechanism and cutting agency are at a distance from a reaction cup receiving hole.Disc type reaction unit of the invention, two uniform shaking mechanisms and feed mechanism and cutting agency location arrangements are reasonable, can sufficiently look after cleaning, reaction solution filling, the space requirement between upper and lower discharge position, time requirement.
Description
Technical field
The present invention relates to a kind of analyzer disc type reaction units, belong to the field of medical instrument technology.
Background technique
Immunoassay is the multiclass detection project such as important means of clinic diagnosis, including virus, hormone, tumor markers.
Chemiluminescence immune assay is the newest immune detection skill to grow up after radio-immunity, fluorescence immunoassay, EIA enzyme immunoassay
Art avoids the interference of bias light and stray light, reduces noise since chemiluminescence immune assay does not use any light source,
Signal-to-noise ratio is substantially increased, and the chemical component of nanogram level or pieck stage can be measured, therefore chemiluminometry has spirit
The advantages that sensitivity is high, detection range is wide, marker stability is good becomes the most important hand of ion vitro immunization detection increasingly
Section.Full-automatic chemiluminescence immunoassay analysis meter working method based on chemiluminescence mechanismic design is mainly that sample-adding-incubation-is clear
Wash-measure four steps.
Incubation is form a connecting link the step of, and incubating is usually to carry out on the disk of a rotation of reaction system,
On the one hand, there is liquid reaction cup to be detected to be constantly put on disk, from injection needle to reaction after disk rotational to certain angle
Injection detection liquid and magnetic bead in cup, for entire disk by keeping certain temperature by heating device simultaneously, final reaction cup can be from circle
It is taken away on disk into cleaning step.In the prior art, since reaction system needs to be cooperated with each component, usually cooperate
Unreasonable situation.
Summary of the invention
The technical problem to be solved by the present invention is in order to overcome the problems referred above, providing a kind of point of spatial position connection and reasonable arrangement
Analyzer disc type reaction unit.
The technical solution adopted by the present invention to solve the technical problems is:
The present invention provides a kind of analyzer disc type reaction unit, comprising:
React disc mechanism, including cylinder, the disk being rotatably arranged in cylinder is isometrical on disk to be placed with circle reaction
Cup receiving hole, reaction cup can be placed in reaction cup receiving hole；
Driving mechanism, for driving disk rotational；
The front end of manipulator crawl position is arranged in uniform shaking mechanism；
Feed mechanism and cutting agency are located at cylinder side；
Uniform shaking mechanism has two groups, wherein the arc length distance of one group of uniform shaking mechanism to feed mechanism is round for 1/3-1/4, two
The arc length distance of uniform shaking mechanism is 2/3-3/4 circle, and the distance of second group of uniform shaking mechanism to cutting agency is held at a distance of 2 reaction cups
Receive the distance in hole, feed mechanism is with cutting agency at a distance from 2 reaction cup receiving holes.
Preferably, analyzer disc type reaction unit of the invention, comprising: lifting actuator, lifter plate are fixed on cylinder bottom
Portion shakes up actuator, by shaft coupling and the rocking bar for shaking up actuator and connecting, the eccentric cup at the top of rocking bar is arranged in, is fixed on
The elastic piece extending at the top of disk on cylinder is provided with for covering the lid wheel at the top of reaction cup, eccentric cup on elastic piece
Central axes and rocking bar central axes it is not conllinear.
Preferably, analyzer disc type reaction unit of the invention, the central axes of eccentric cup are at a distance from the central axes of rocking bar
It is 1/8 to the 1/4 of reaction cup width.
Preferably, analyzer disc type reaction unit of the invention, lid wheel bottom have the circle wheel that can extend into reaction cup.
Preferably, analyzer disc type reaction unit of the invention, lid wheel bottom have silastic-layer.
Preferably, analyzer disc type reaction unit of the invention, eccentric cup are made of magnet steel, and the magnetic pole of eccentric cup is located at top
Bottom both ends.
Preferably, analyzer disc type reaction unit of the invention, feed mechanism is identical with the structure of cutting agency, but opposite
Setting, includes rack, electromagnetic driver, the oscillating deck being hingedly arranged at, on oscillating deck setting there are two parallel yoke,
Oscillating deck also passes through the telescopic rod that spring makes oscillating deck abut against electromagnetic driver always, and electromagnetic driver is after by electricity, telescopic rod
It stretches out, oscillating deck is pushed to swing, after electromagnetic driver power-off, telescopic rod is retracted.
Preferably, analyzer disc type reaction unit of the invention, when shaking up, shaking up actuator makes reaction cup to a direction
8-15s is rotated with 600-1200 rpms of speed.
Preferably, analyzer disc type reaction unit of the invention, the distance of two neighboring reaction cup receiving hole is on disk
The half of reaction cup width is to 2/3.
The beneficial effects of the present invention are: analyzer disc type reaction unit of the invention, a uniform shaking mechanism to feed mechanism
Arc length distance be 1/3-1/4 circle, the arc length distance of two uniform shaking mechanisms is round for 2/3-3/4, and second uniform shaking mechanism arrives
The distance of cutting agency is at a distance of the distance of reaction cup receiving hole, feed mechanism and cutting agency at a distance of reaction cup receiving hole
Distance, in above-mentioned analyzer disc type reaction unit, two uniform shaking mechanisms and feed mechanism and cutting agency location arrangements are reasonable, energy
Sufficiently look after cleaning, reaction solution filling, the space requirement between upper and lower discharge position, time requirement.
Detailed description of the invention
Present invention will be further explained below with reference to the attached drawings and examples.
Fig. 1 is a kind of three-dimensional structure diagram of embodiment of analyzer disc type reaction unit of the present invention；
Fig. 2 is a kind of three-dimensional structure diagram of embodiment of analyzer disc type reaction unit of the present invention；
Fig. 3 is a kind of three-dimensional structure diagram of embodiment of feed mechanism or cutting agency of the present invention；
Fig. 4 is a kind of three-dimensional structure diagram of embodiment of uniform shaking mechanism of the present invention.
Appended drawing reference are as follows:
100- reacts disc mechanism；110- cylinder；120- disk；121- reaction cup receiving hole；200- driving mechanism；300- shakes
Even mechanism；310- shakes up actuator；311- rocking bar；321- elastic piece；322- lid wheel；330- bias cup；400- feed mechanism；
410- electromagnetic driver；420- rack；430- oscillating deck；500- cutting agency；900- reaction cup.
Specific embodiment
In conjunction with the accompanying drawings, the present invention is further explained in detail.These attached drawings are simplified schematic diagram, only with
Illustration illustrates basic structure of the invention, therefore it only shows the composition relevant to the invention.
Embodiment
The present embodiment provides a kind of analyzer disc type reaction units, as shown in Figure 1, comprising:
React disc mechanism 100, including cylinder 110, the disk 120 being rotatably arranged in cylinder 110, on disk 120 etc.
Diameter is placed with a circle reaction cup receiving hole 121, and reaction cup 900 can be placed in reaction cup receiving hole 121, adjacent on disk 120
The distance of two reaction cup receiving holes 121 is the half of 900 width of reaction cup to 2/3；
Driving mechanism 200, for driving disk 120 to rotate；
The front end of manipulator crawl position is arranged in uniform shaking mechanism 300, comprising: lifting actuator, lifter plate are fixed on circle
110 bottoms of cylinder shake up actuator 310, and by shaft coupling and the rocking bar 311 for shaking up actuator 310 and connecting, setting is in rocking bar 311
The eccentric cup 330 at top, the elastic piece 321 for extending into the top of disk 120 being fixed on cylinder 110 are arranged on elastic piece 321
Have for covering the lid wheel 322 at 900 top of reaction cup, 322 bottoms of lid wheel have the circle wheel that can extend into reaction cup 900, partially
The central axes of heart cup 330 are not conllinear with the central axes of rocking bar 311, the central axes of the central axes and rocking bar 311 of eccentric cup 330 away from
It (is 1cm than 900 width of reaction cup, then distance is 2-2.5mm, otherwise reaction cup from 1/8 to 1/4 for 900 width of reaction cup
Liquid in 900 can be overflowed because shaking amplitude is big), when shaking up to reaction cup 900, lifting actuator drives lifter plate
It rises, shakes up actuator 310, rocking bar 311, eccentric cup 330 and risen with lifter plate, eccentric cup 330 (makes the jack-up of reaction cup 900
Reaction cup 900 is obtained not limited by reaction cup receiving hole 121), the top of reaction cup 900 resists the lid wheel 322 of elastic piece 321,
Reaction cup 900 is fixed again, shakes up the starting of actuator 310 later, is shaken reaction cup 900 by eccentric cup 330, is made reaction cup
Liquid shakes up in 900, and 322 bottoms of lid wheel have silastic-layer, and when shaking up, shaking up actuator 310 makes reaction cup 900 to a side
8-15s is rotated to 600-1200 rpms of speed.It allows fluid to obtain best mixing within the least time
Effect；
Eccentric cup 330 is made of magnet steel, and the magnetic pole of eccentric cup 300 is located at top and bottom ends, and setting magnet can make magnetic bead more
Add close to bottom, obtains and preferably shake up effect.
Feed mechanism 400 and cutting agency 500 are located at 110 side of cylinder, the knot of feed mechanism 400 and cutting agency 500
Structure is identical, but is oppositely arranged, and includes rack 420, electromagnetic driver 410, the oscillating deck 430 being hingedly arranged at, oscillating deck
There are two parallel yokes 431, oscillating deck 430 also so that oscillating deck 430 is abutted against electromagnetic drive always by spring for setting on 430
The telescopic rod of part 410, after by electricity, telescopic rod stretches out electromagnetic driver 410, pushes oscillating deck 430 to swing, electromagnetic driver 410
After power-off, telescopic rod is retracted；
Also settable heating mechanism, heating mechanism is set on 110 inner wall of cylinder, for heating reaction cup, preferably silicon
Glue heater.
There are two uniform shaking mechanisms 300, and the arc length distance of one of uniform shaking mechanism 300 to feed mechanism 400 is 1/3-1/4
A circle, the arc length distance of two uniform shaking mechanisms 300 are 2/3-3/4 circle, second uniform shaking mechanism 300 to cutting agency 500
Distance is at a distance of the distance of 2 reaction cup receiving holes 121, and feed mechanism 400 and cutting agency 500 are at a distance of 2 reaction cup receiving holes
121 distance, in above-mentioned analyzer disc type reaction unit, two uniform shaking mechanisms 300 and feed mechanism 400 and cutting agency 500
Location arrangements are reasonable, can sufficiently look after cleaning, reaction solution filling, the space requirement between upper and lower discharge position, time requirement.
Taking the above-mentioned ideal embodiment according to the present invention as inspiration, through the above description, relevant staff is complete
Various changes and amendments can be carried out without departing from the scope of the technological thought of the present invention' entirely.The technology of this invention
Property range is not limited to the contents of the specification, it is necessary to which the technical scope thereof is determined according to the scope of the claim.
Claims (8)
1. a kind of analyzer disc type reaction unit characterized by comprising
It reacts disc mechanism (100), including cylinder (110), the disk (120) being rotatably arranged in cylinder (110), disk
(120) isometrical on to be placed with a circle reaction cup receiving hole (121), reaction cup (900) can be placed in reaction cup receiving hole (121)
It is interior；
Driving mechanism (200), for driving disk (120) to rotate；
The front end of manipulator crawl position is arranged in uniform shaking mechanism (300)；
Feed mechanism (400) and cutting agency (500) are located at cylinder (110) side；
Uniform shaking mechanism (300) has two groups, wherein the arc length distance of one group of uniform shaking mechanism (300) to feed mechanism (400) is 1/3-
1/4 circle, the arc length distance of two uniform shaking mechanisms (300) are 2/3-3/4 circle, and second group of uniform shaking mechanism (300) arrives blanking machine
The distance of structure (500) is at a distance of the distance of 2 reaction cup receiving holes (121), and feed mechanism (400) and cutting agency (500) are at a distance of 2
The distance of a reaction cup receiving hole (121)；
Feed mechanism (400) is identical with the structure of cutting agency (500), but is oppositely arranged, and includes rack (420), and electromagnetism drives
Moving part (410), the oscillating deck being hingedly arranged at (430), there are two parallel yoke (431), pendulum for setting on oscillating deck (430)
Movable plate (430) also makes oscillating deck (430) abut against the telescopic rods of electromagnetic driver (410), electromagnetic driver always by spring
(410) after by electricity, telescopic rod stretches out, and oscillating deck (430) is pushed to swing, and after electromagnetic driver (410) power-off, telescopic rod is retracted；
The analyzer disc type reaction unit further includes heating mechanism, and the heating mechanism is set on cylinder (110) inner wall, is used
In heating reaction cup.
2. analyzer disc type reaction unit according to claim 1 characterized by comprising lifting actuator, lifting
Plate, be fixed on cylinder (110) bottom shakes up actuator (310), passes through shaft coupling and the rocking bar that shakes up actuator (310) and connect
(311), the eccentric cup (330) being arranged at the top of rocking bar (311) is fixed on extending at the top of disk (120) on cylinder (110)
Elastic piece (321), be provided with for covering the lid wheel (322) at the top of reaction cup (900), eccentric cup on elastic piece (321)
(330) central axes are not conllinear with the central axes of rocking bar (311).
3. analyzer disc type reaction unit according to claim 2, which is characterized in that the central axes of eccentric cup (330) with
The distance of the central axes of rocking bar (311) is 1/8 to the 1/4 of reaction cup (900) width.
4. analyzer disc type reaction unit according to claim 2, which is characterized in that lid wheel (322) bottom has can
Protrude into the circle wheel in reaction cup (900).
5. analyzer disc type reaction unit according to claim 4, which is characterized in that the lid wheel (322) bottom has
Silastic-layer.
6. according to the described in any item analyzer disc type reaction units of claim 2-5, which is characterized in that eccentric cup (330) by
Magnet steel is made, and the magnetic pole of eccentric cup (330) is located at top and bottom ends.
7. analyzer disc type reaction unit according to claim 1, which is characterized in that when shaking up, shake up actuator (310)
Reaction cup (900) is set to rotate 8-15s to a direction with 600-1200 rpms of speed.
8. analyzer disc type reaction unit according to claim 1, which is characterized in that two neighboring anti-on disk (120)
The distance for answering a glass receiving hole (121) is the half of reaction cup (900) width to 2/3.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710498779.8A CN107389960B (en) | 2017-06-27 | 2017-06-27 | A kind of analyzer disc type reaction unit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710498779.8A CN107389960B (en) | 2017-06-27 | 2017-06-27 | A kind of analyzer disc type reaction unit |
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| CN107389960A CN107389960A (en) | 2017-11-24 |
| CN107389960B true CN107389960B (en) | 2019-08-13 |
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| CN201710498779.8A Active CN107389960B (en) | 2017-06-27 | 2017-06-27 | A kind of analyzer disc type reaction unit |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107247133A (en) * | 2017-06-27 | 2017-10-13 | 苏州长光华医生物医学工程有限公司 | A kind of analyzer reaction system |
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| JP3739547B2 (en) * | 1997-10-22 | 2006-01-25 | オリンパス株式会社 | Automatic analyzer |
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| CN102288774A (en) * | 2011-06-16 | 2011-12-21 | 深圳市国赛生物技术有限公司 | Full-automatic chemiluminescence testing method and device |
| CN205003167U (en) * | 2015-09-11 | 2016-01-27 | 四川迈克生物医疗电子有限公司 | Reaction tube pusher and sample analysis appearance |
| CN205193081U (en) * | 2015-12-17 | 2016-04-27 | 嘉兴凯实生物科技有限公司 | Reaction plate and automatic spotting instrument |
| CN206975052U (en) * | 2017-06-27 | 2018-02-06 | 苏州长光华医生物医学工程有限公司 | A kind of analyzer disc type reaction unit |
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2017
- 2017-06-27 CN CN201710498779.8A patent/CN107389960B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3739547B2 (en) * | 1997-10-22 | 2006-01-25 | オリンパス株式会社 | Automatic analyzer |
| CN102147406A (en) * | 2011-02-14 | 2011-08-10 | 四川迈克生物科技股份有限公司 | Fully automatic chemical luminescent immune analyzer |
| CN102288774A (en) * | 2011-06-16 | 2011-12-21 | 深圳市国赛生物技术有限公司 | Full-automatic chemiluminescence testing method and device |
| CN205003167U (en) * | 2015-09-11 | 2016-01-27 | 四川迈克生物医疗电子有限公司 | Reaction tube pusher and sample analysis appearance |
| CN205193081U (en) * | 2015-12-17 | 2016-04-27 | 嘉兴凯实生物科技有限公司 | Reaction plate and automatic spotting instrument |
| CN206975052U (en) * | 2017-06-27 | 2018-02-06 | 苏州长光华医生物医学工程有限公司 | A kind of analyzer disc type reaction unit |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107247133A (en) * | 2017-06-27 | 2017-10-13 | 苏州长光华医生物医学工程有限公司 | A kind of analyzer reaction system |
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