CN107375851A - For treating the medicine of scleroderma circumscriptum - Google Patents

For treating the medicine of scleroderma circumscriptum Download PDF

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Publication number
CN107375851A
CN107375851A CN201710724706.6A CN201710724706A CN107375851A CN 107375851 A CN107375851 A CN 107375851A CN 201710724706 A CN201710724706 A CN 201710724706A CN 107375851 A CN107375851 A CN 107375851A
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parts
medicine
rhizome
ginseng
circumscriptum
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史长林
宋艳丽
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Minle County Ruyi Ruyi Planting Co Ltd
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Minle County Ruyi Ruyi Planting Co Ltd
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger

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Abstract

The invention discloses a kind of medicine for being used to treat scleroderma circumscriptum, to solve the problems, such as that current medicine can not effect a radical cure scleroderma circumscriptum.It includes the raw material of following parts by weight：15 25 parts of RADIX ACONITI LATERALIS PREPARATA, 10 20 parts of ginseng, 10 20 parts of keel, 39 parts of levisticum, 6 12 parts of caulis sinomenii, 39 parts of rhizome of chuanxiong, 5 15 parts of the fruit of Chinese wolfberry, 5 15 parts of the red sage root, 39 parts of rhizoma cibotii, 5 15 parts of the bighead atractylodes rhizome, 6 12 parts of turmeric, 39 parts of radix glycyrrhizae.The advantage of the invention is that used Chinese medicine has no side effect, is safe and reliable, be curative for effect, is quick, cure rate is high.

Description

For treating the medicine of scleroderma circumscriptum
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of medicine for being used to treat scleroderma circumscriptum.
Background technology
Scleroderma circumscriptum is also known as morphoea, is a kind of limit office property skin turgor, gradually hardens the skin disease of atrophy. It is apt to occur in scalp, forehead, waist and belly and four limbs.Skin lesion from the beginning of the pale red to differ in size, slightly oedema macula, single-shot or It is multiple.Gradually hardening is in faint yellow or yellow-white later.Surface is smooth shinny such as waxy, central nick, trichomadesis at skin lesion, Perspire and reduce, surrounding capillaries expansion, deepen in aubergine or pigment.Late period atrophoderma, hypopigmentation.Skin lesion shape is not One, divide patch shape, banding, point drop-wise, general four kinds of hair property according to form difference, wherein most common with patch shape.Limitation sclerderm The cause of disease of disease is unclear, and local excitation such as wound take part in morbidity, and related to infection.Patient often have the slight itch of skin or The symptom such as tingling sensation, gradual bradythesia.
Scleroderma circumscriptum there is no specific short at present.The infringement of scleroderma circumscriptum small pieces can be selected procaine and add cortex Injected in steroids suspension such as prednisolone or triamcinolone, local intradermal injection or skin lesion.Also can external application fluorinated corticosteroid Preparation.For progressivity or the focal chorionitis of severe, suitable whole body glucocorticoid and immunodepressant.Clinic uses first Aminopterin, penicillamine, mycophenolate, imuran, HCQ and cyclosporine, have certain effect, but DeGrain.And control The Chinese medicine of scleroderma circumscriptum is treated, time length, it is impossible to effect a radical cure scleroderma circumscriptum the problem of big there is dose.
The content of the invention
, can not root to solve current medicine it is an object of the invention to provide a kind of medicine for being used to treat scleroderma circumscriptum The problem of controlling scleroderma circumscriptum.
Technical scheme is as follows：A kind of medicine for being used to treat scleroderma circumscriptum, by the original of following parts by weight Material composition：RADIX ACONITI LATERALIS PREPARATA 15-25 parts, ginseng 10-20 parts, keel 10-20 parts, levisticum 3-9 parts, caulis sinomenii 6-12 parts, rhizome of chuanxiong 3-9 Part, fruit of Chinese wolfberry 5-15 parts, red sage root 5-15 parts, rhizoma cibotii 3-9 parts, bighead atractylodes rhizome 5-15 parts, turmeric 6-12 parts, radix glycyrrhizae 3-9 parts.
Preferably, the parts by weight composition of each raw material is 20 parts of RADIX ACONITI LATERALIS PREPARATA, 15 parts of ginseng, 15 parts of keel, 6 parts of levisticum, blue or green wind 9 parts of rattan, 6 parts of rhizome of chuanxiong, 10 parts of the fruit of Chinese wolfberry, 10 parts of the red sage root, 6 parts of rhizoma cibotii, 10 parts of the bighead atractylodes rhizome, 9 parts of turmeric, 6 parts of radix glycyrrhizae.
Said medicine preparation process is as follows：By material medicine RADIX ACONITI LATERALIS PREPARATA, ginseng, keel, levisticum, caulis sinomenii, rhizome of chuanxiong, matrimony vine Son, the red sage root, rhizoma cibotii, the bighead atractylodes rhizome, turmeric, radix glycyrrhizae, are respectively prepared medicine materical crude slice, by pressure cooker cooking disinfection 30-45 minutes, dry, obtain Aseptic raw material is obtained, then aseptic raw material is made into Chinese medicine preparation to take.
RADIX ACONITI LATERALIS PREPARATA has recuperating depleted yang, mends fire supporing yang in the present invention, and the work(by wind-cold damp pathogen is monarch drug in a prescription.Ginseng, keel, solely Work, caulis sinomenii, rhizome of chuanxiong, the fruit of Chinese wolfberry, the red sage root reinforce vital energy, and veins takes off admittedly, reinforce the spleen to benefit the lung, and promote the production of body fluid, tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, Stop blooding puckery intestines, myogenic sore, dispelling wind and eliminating dampness, and arthritis analgesic, diuresis, blood-activating and qi-promoting is nourishing liver and kidney, benefiting shrewd head, dissolving stasis, leads to Through relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle is ministerial drug.Rhizoma cibotii, the bighead atractylodes rhizome, turmeric wind-damp dispelling, filling liver kidney, strong waist and knee, tonifying middle-Jiao and Qi, invigorating the spleen and Stomach, eliminate dampness and have diuretic effect, antiemetic rush down, and hidroschesis is antiabortive, blood-breaking, promoting the circulation of qi, stimulates the menstrual flow, and relieve pain as adjutant.Radix glycyrrhizae is invigorated the spleen and benefited qi, and is moistened the lung and relieve the cough, It is clearing heat and detoxicating, alleviate analgesic, coordinating the drug actions of a prescription is to make medicine.
The property of medicine and its effect of each component of the present invention are as follows：
RADIX ACONITI LATERALIS PREPARATA, extremely hot in nature, acrid flavour, sweet, the thoughts of returning home, kidney, the spleen channel.Major function：Recuperating depleted yang, mends fire supporing yang are wet by chill It is evil.Cure mainly：Yang depletion is collapsed, cold weak pulse of limb, impotence, Gong Leng, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, cold-dampness Numbness pain.
Ginseng, warm-natured, flat, sweet, slight bitter, returns spleen, lung, the heart channel of Hang-Shaoyin.Major function：Reinforce vital energy, veins takes off admittedly, tonifying spleen Beneficial lung, promotes the production of body fluid, and calms the nerves.Cure mainly：Physically weak to be taken off, cold weak pulse of limb, spleen eating less, the deficiency syndrome of the lung breathes with cough, injury thirst, Heat Diabetes, long Thin, the insomnia of palpitating with fear of sick void, impotence Gong Leng；Heart failure, cardiogenic shock.
Keel, mild-natured, sweet-puckery flavor, the thoughts of returning home, liver, kidney, large intestine channel.Major function：Tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, hemostasis are puckery Intestines, myogenic sore.Cure mainly：Frightened epilepsy is demented, and palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, and stranguria with turbid discharge of passing out semen, hematemesis is had blood in stool, uterine bleeding band Under, rush down dysentery prolapse of the anus, ulcer does not close up long.
Levisticum, slightly warm in nature, acrid flavour, hardship, return kidney, bladder warp.Major function：Dispelling wind and eliminating dampness, arthritis analgesic.Cure mainly：Chill Arthritis with fixed pain caused by dampness, will wash pain, few the moon volt wind headache, and chill holds wet headache under the arm.
Caulis sinomenii, mild-natured, bitter, pungent, Return liver, the spleen channel.Major function：Wind-damp dispelling, diuresis.Cure mainly：Arthralgia pain due to rheumatism, The arthroncus of knee, oedema, tinea pedis.
Rhizome of chuanxiong, meridian distribution of property and flavor：It is warm-natured, acrid flavour, Return liver, courage, pericardium channel.Major function：Blood-activating and qi-promoting, wind-expelling pain-stopping.It is main Control：Irregular menstruation, closed dysmenorrhea, stomachache, sternal rib shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism.
The fruit of Chinese wolfberry, it is mild-natured, it is sweet, return liver and kidney channel.Major function：It is nourishing liver and kidney, benefiting shrewd head.Cure mainly vertigo, Hypopsia, soreness and weakness of waist and knees, seminal emission, the deficiency of Yin are quenched one's thirst.
The red sage root, meridian distribution of property and flavor：Cold nature, bitter, the thoughts of returning home, Liver Channel.Major function：Promoting blood circulation, it is inducing meastruation to relieve menalgia, clear away heart-fire and remove It is tired, cool blood to disappear carbuncle.For chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhoea warp Close, sore swell and ache curative.
Rhizoma cibotii, it is warm-natured, it is bitter, sweet, return liver and kidney channel.Major function：Wind-damp dispelling, filling liver kidney, strong waist and knee.Cure mainly：Rheumatism Numbness pain, soreness and weakness of waist and knees, weakness of the lower extremities.
The bighead atractylodes rhizome, meridian distribution of property and flavor：Slightly warm in nature, sweet, bitter, returns spleen, stomach.Major function：Tonifying middle-Jiao and Qi, strengthening the spleen and stomach are dry Wet Li Shui, antiemetic rush down, and hidroschesis is antiabortive.Cure mainly：The middle deficiency of vital energy is weak, indigestion, oedema turgor, vomiting dysentery, fetal irritability, body Empty spontaneous perspiration.
Turmeric, it is warm-natured, acrid flavour, hardship, return liver and kidney channel.Major function：Blood-breaking, promoting the circulation of qi, stimulate the menstrual flow, relieve pain.Cure mainly：Trusted subordinate's ruffian Full distending pain, brachialgia, abdominal mass, women's blood stasis, the postpartum stasis of blood stop suffering from abdominal pain, injury from falling down, carbuncle swells.
Radix glycyrrhizae, mild-natured, sweet, return 12 warps.Major function：Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency is stopped Bitterly, coordinating the drug actions of a prescription.Cure mainly：It is weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle swells sore Poison, alleviate drug toxicity, strong.
The Chinese medicine of present invention treatment scleroderma circumscriptum has a recuperating depleted yang, mends fire supporing yang, by wind-cold damp pathogen, big complement Gas, veins takes off admittedly, reinforce the spleen to benefit the lung, promote the production of body fluid, tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines, myogenic sore, the analgesic of wind-dispelling arthritis, living Blood gas, nourishing liver and kidney, benefiting shrewd head, dissolving stasis, relieving restlessness that clears away heart-fire, cool blood to disappear carbuncle, strong waist and knee, tonifying middle-Jiao and Qi, strengthening the spleen and stomach, eliminating dampness Li Shui, antiemetic rush down, and hidroschesis is antiabortive, blood-breaking, stimulates the menstrual flow, clearing heat and detoxicating, expelling phlegm and arresting coughing, the effect of coordinating the drug actions of a prescription, and evident in efficacy, It is quick, securely and reliably,
Without obvious toxic-side effects, scleroderma circumscriptum can be effectively treated.
Embodiment
The following examples can further illustrate the present invention, but do not limit the invention in any way.
Embodiment 1, the medicine composition for treating scleroderma circumscriptum：RADIX ACONITI LATERALIS PREPARATA 20g, ginseng 15g, keel 15g, levisticum 6g, caulis sinomenii 9g, rhizome of chuanxiong 6g, fruit of Chinese wolfberry 10g, red sage root 10g, rhizoma cibotii 6g, bighead atractylodes rhizome 10g, turmeric 9g, radix glycyrrhizae 6g.
Embodiment 2, the medicine composition for treating scleroderma circumscriptum：RADIX ACONITI LATERALIS PREPARATA 25g, ginseng 20g, keel 20g, levisticum 9g, caulis sinomenii 12g, rhizome of chuanxiong 9g, fruit of Chinese wolfberry 15g, red sage root 15g, rhizoma cibotii 9g, bighead atractylodes rhizome 15g, turmeric 12g, radix glycyrrhizae 9g.The present embodiment Drug effect is stronger.
Embodiment 3, the medicine composition for treating scleroderma circumscriptum：RADIX ACONITI LATERALIS PREPARATA 15g, ginseng 10g, keel 10g, levisticum 3g, caulis sinomenii 6g, rhizome of chuanxiong 3g, fruit of Chinese wolfberry 5g, red sage root 5g, rhizoma cibotii 3g, bighead atractylodes rhizome 5g, turmeric 6g, radix glycyrrhizae 3g.Embodiment drug effect is slightly It is weak.
Above-described embodiment preparation process is as follows：RADIX ACONITI LATERALIS PREPARATA, ginseng, keel, levisticum, caulis sinomenii, rhizome of chuanxiong, the fruit of Chinese wolfberry, the red sage root, Rhizoma cibotii, the bighead atractylodes rhizome, turmeric, radix glycyrrhizae, are respectively prepared medicine materical crude slice, by pressure cooker cooking disinfection 30-45 minutes, dry, obtain sterile original Material, then aseptic raw material is made into Chinese medicine preparation can take, in each 1 time of daily evening in morning, 7 are a course for the treatment of.
《Clinical trial》
The effect of to show medicine of the present invention, 300 patients for being diagnosed as scleroderma circumscriptum are taken, its cardinal symptom has for skin Slight itch or the symptom such as tingling sensation, gradual bradythesia.
It is divided into two groups to be treated, one of which is control group, and one group is observation group, and each 150 of two groups of cases, two groups sick Example does not have comparativity in age, sex, illness weight etc..Control group uses to prednisolone by specification, and 7 are one The course for the treatment of, treat the 2-6 course for the treatment of；Medicine made from observation group's one after each meal embodiment of the present invention 1, once in the morning and once at night, 7 are a treatment Journey, treat the 2-6 course for the treatment of.Two groups with cardinal symptom：Skin is gradually regained consciousness to be effective, with cardinal symptom：Skin is light Spend itch or tingling sensation disappears for recovery from illness.Vertical shelves, which stay to look into, is subject to Statistical Comparison, and statistics shows to the results are shown in Table 1（Control group curative effect feelings Condition）With table 2（Experimental group curative effect situation）, by the contrast to control group and experimental group, drug therapy limitation sclerderm of the present invention The positive effect of disease is better than the effect of prednisolone.Medication effect of the present invention：It is efficient：90%, cure rate
86%。
《Model case》
1st, Lee, man, 37 years old, skin occur slight itch or tingling sensation, gradual bradythesia symptom 6 months.Using this hair Bright described medicine is treated, and in each 1 time of daily evening in morning, 7 be a course for the treatment of, and after 2 courses for the treatment of are used in conjunction, skin gradually know by recovery Feel, after 3 courses for the treatment of, skin is regained consciousness, and itch or tingling sensation symptom disappear.It is further continued for taking 1 course for the treatment of day to consolidate curative effect, Follow-up 2 years is without recurrence.
2nd, Zhang, female, 33 years old, occurring skin repeatedly had slight itch or tingling sensation, gradual bradythesia symptom 1 year.Should Treated with medicine of the present invention, in each 1 time of daily evening in morning, 7 are a course for the treatment of, and after 3 courses for the treatment of are used in conjunction, skin is gradually extensive Multiple consciousness, after 4 courses for the treatment of, skin is regained consciousness, and itch or tingling sensation symptom disappear.It is further continued for taking 1 course for the treatment of day to consolidate Curative effect, follow-up 2 years is without recurrence.

Claims (2)

1. a kind of medicine for being used to treat scleroderma circumscriptum, it is characterised in that it is made up of the raw material of following parts by weight：Make attached Sub- 15-25 parts, ginseng 10-20 parts, keel 10-20 parts, levisticum 3-9 parts, caulis sinomenii 6-12 parts, rhizome of chuanxiong 3-9 parts, fruit of Chinese wolfberry 5-15 Part, red sage root 5-15 parts, rhizoma cibotii 3-9 parts, bighead atractylodes rhizome 5-15 parts, turmeric 6-12 parts, radix glycyrrhizae 3-9 parts.
2. the medicine for being used to treat scleroderma circumscriptum according to claim 1, it is characterised in that：The weight of each raw material Part composition is 20 parts of RADIX ACONITI LATERALIS PREPARATA, 15 parts of ginseng, 15 parts of keel, 6 parts of levisticum, 9 parts of caulis sinomenii, 6 parts of rhizome of chuanxiong, 10 parts of the fruit of Chinese wolfberry, pellet 10 parts of ginseng, 6 parts of rhizoma cibotii, 10 parts of the bighead atractylodes rhizome, 9 parts of turmeric, 6 parts of radix glycyrrhizae.
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CN105106396A (en) * 2015-09-30 2015-12-02 成都倍加特生物科技有限公司 Oral medicine capable of effectively treating localized scleroderma and preparation method thereof
CN106362122A (en) * 2016-10-27 2017-02-01 谭奇纹 Traditional Chinese medicine for treating localized scleroderma

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