CN107362449A - A kind of radio communication circuit structure and method applied to Implanted cardiac pacemaker - Google Patents
A kind of radio communication circuit structure and method applied to Implanted cardiac pacemaker Download PDFInfo
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- CN107362449A CN107362449A CN201710488913.6A CN201710488913A CN107362449A CN 107362449 A CN107362449 A CN 107362449A CN 201710488913 A CN201710488913 A CN 201710488913A CN 107362449 A CN107362449 A CN 107362449A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37276—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data characterised by means for reducing power consumption during telemetry
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B1/00—Details of transmission systems, not covered by a single one of groups H04B3/00 - H04B13/00; Details of transmission systems not characterised by the medium used for transmission
- H04B1/38—Transceivers, i.e. devices in which transmitter and receiver form a structural unit and in which at least one part is used for functions of transmitting and receiving
- H04B1/40—Circuits
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- Heart & Thoracic Surgery (AREA)
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Abstract
The invention discloses one kind to be applied to private radio communication circuit structure and method inside Implanted cardiac pacemaker, and the circuit structure can meet following functions:Parameter preset can be transferred in the functional device to implant by vitro program controlled instrument by telecommunication circuit;The functional device to implant can be by radio communication circuit by the ECG Data Transmission Based that the hardware information being stored in MCU, various parameters, battery status, data on file and pacemaker special circuit detect to vitro program controlled instrument.The circuit structure disclosure satisfy that following characteristics:Communication distance in the case where passing through human body and titanium shell with vitro program controlled instrument is more than 10cm;It is higher to external transmission data rate in vivo;The bit error rate of telecommunication circuit is less than ten a ten thousandths;The stand-by power consumption of telecommunication circuit is extremely low;The operating power consumption of telecommunication circuit disclosure satisfy that the ordinary life demand of pacemaker;At a temperature of 37 DEG C of fluid environment, continuous communiction 0.5 hour, titanium shell surface temperature, which rises, is less than 2 DEG C.
Description
Technical field
The invention belongs to biologic medical application specific integrated circuit field, and in particular to one kind is applied to Implanted cardiac pacemaker
Radio communication circuit structure.
Background technology
Implanted cardiac pacemaker is a kind of implantable medical device, and working environment usually requires that these in inside of human body
Equipment has sufficiently strong information processing capability, using the teaching of the invention it is possible to provide data telemetry function.Now, with the development of engineering technology, entirely
Most implanted equipment can be carried out program control by outside program control instrument in vivo in world wide, to obtain more preferable work
Efficiency.The pacemaker of implanted is typically required to the continuous firing in human body by single non-exchange battery powered
10 years are even more long, it is necessary to have extremely low power consumption, to increase the service life and reduce thermal diffusion.In addition, in order to reduce patient
Sense of discomfort, the chip area in Implanted cardiac pacemaker should be as small as possible.Therefore, this circuit system needs to use big rule
Vlsi die technology, advanced wireless technology and power management techniques.
The telemetry function and data-transformation facility of the Implanted cardiac pacemaker used now are typically by pacemaker and in vitro
Program control instrument two-way communication complete.
Present Implanted cardiac pacemaker radio communication circuit is usually to be built using FPGA and discrete component, phase
Than in using full custom application specific integrated circuit, shortcoming is that integrated level is low, area is bigger, power consumption is higher, performance does not have advantage, excellent
Point is that the development time is shorter, cost is lower.
The communication mode of existing implanted equipment will be loaded on coil after modulates information, is demodulated and carried out by resonance
Transmission.Telecommunication circuit in the present invention carries out data transmission by way of coil couples mutual inductance, and internal receiving terminal is without demodulation
Circuit, it reduce further the complexity and power consumption of circuit.
During pacemaker transmits electrocardiogram (ECG) data to program control instrument, the electrocardiosignal that is collected by electrode passes through ASIC
Interlock circuit collect, and be sent into MCU and parsed.The scheme of existing pacemaker be usually by MCU by data processing with
It is transmitted afterwards by transmitting tube and coil, during so carrying out ECG Data Transmission Based, MCU caloric values are big, and patient will feel
To obvious discomfort.
The content of the invention
It is an object of the invention to meet various current functional requirements, there is provided one kind is applied to implantable cardiac and paced
The radio communication circuit structure and method of device, the area of existing Implanted cardiac pacemaker radio communication circuit, power consumption is overcome to ask
Topic, and the heating problem of currently existing scheme transmission electrocardiogram (ECG) data, are provided a set of for Implanted cardiac pacemaker application specific integrated circuit
Feasible communication circuit module structure.
To achieve the above object, the present invention uses following technical scheme.
A kind of radio communication circuit structure applied to Implanted cardiac pacemaker, including radio communication circuit, the nothing
Line telecommunication circuit includes filtration module, amplifier module, hysteresis comparator module, waveform-shaping module, synchronization module, decoding mould
Block, wake-up circuit module, transmitting tube module, communication code module, hybrid coding module and internal coil L;Vitro program controlled instrument
It is of coupled connections by external coil L and internal coil L, internal coil L is sequentially connected filtration module, amplifier module, sluggish ratio
Compared with device module, waveform-shaping module, waveform-shaping module respectively by synchronization module, decoding module and wake-up circuit module with
MCU module connects;MCU module passes sequentially through communication code module, transmitting tube module, internal coil L, and MCU messages are launched
Radio communication circuit module, transmitted through external coil L to vitro program controlled instrument;Module ASIC is connected collection electrocardio number with from heart
According to, and transmit to MCU module;Wireless communication module gathers module ASIC and the electrocardiogram (ECG) data of MCU module passes sequentially through mixing volume
Code module is connected with communication code module.
Described transmitting tube module is bipolar transistor or MOSFET.
Described filtration module is passive filtering structure or active power filtering structure.
Coil L is the special-shaped air core coil along institute's coiling on the inside of Implanted cardiac pacemaker titanium shell inside described.
Described wireless communication module is in addition to internal coil L, using the form of integrated circuit.
For described radio communication circuit when using 0.35 μm of technique, maximum current during work is less than 50 μ A.
Described radio communication circuit uses 32K crystal oscillator clock signals, and radio communication circuit transmits to the highest of program control instrument
Speed is 8.192kbps.
Wherein, the mode and vitro program controlled instrument of logical (internal coil L1 and external coil L2) the overcoupling mutual inductance of communication coil enter
Row data transmitted in both directions, the output of communication coil are connected to the input of filter circuit, and due to no carrier wave, internal receiving terminal need not
Demodulator circuit, it reduce further the complexity and power consumption of circuit;
Filter circuit is opened when program control instrument transmits data to telecommunication circuit, and its input is communication coil, exports and is
The input of amplifier, filter circuit remove the clutter in the signal received by coil, leave useful signal;
Amplifier is when program control instrument transmits data to telecommunication circuit and telecommunication circuit transmits electrocardiogram (ECG) data to program control instrument
During, opened when receiving synchrodata, it inputs output from filter circuit, and amplifier is by filtered signal width
Degree is amplified and is converted into differential signal, and differential signal is exported to the input of hysteresis comparator;
Hysteresis comparator is when program control instrument transmits data to telecommunication circuit and telecommunication circuit transmits electrocardio to program control instrument
In data procedures, opened when receiving synchrodata, it inputs the output from amplifier, and hysteresis comparator is used for will amplification
The analog difference signal of device output is converted to data signal, and data signal is exported to waveform shaping circuit;
Waveform shaping circuit is when program control instrument transmits data to telecommunication circuit and telecommunication circuit transmits the heart to program control instrument
In electric data procedures, opened when receiving synchrodata, it inputs the output from hysteresis comparator, and waveform shaping circuit is used
The data signal of Standard pulse-width is shaped in the data signal for exporting hysteresis comparator, is exported to decoding circuit, synchronous circuit
And wake-up circuit;
Decoding circuit is opened when program control instrument transmits data to telecommunication circuit, and it is inputted from waveform shaping circuit
Output, decoding circuit are used to complete the transformation to the data signal of waveform shaping circuit output from communication coding to data encoding,
Export to the pacemaker built-in MCU outside telecommunication circuit;
Synchronous circuit is opened when telecommunication circuit transmits electrocardiogram (ECG) data to program control instrument, and it is whole that its input is connected to waveform
The output end of shape circuit, synchronous circuit are used for receiving and recognizing the synchronizing signal of vitro program controlled instrument transmitting, and have control to communicate
The function of circuit working state;
In telecommunication circuit, lower opening, its input are connected to the output of waveform shaping circuit to wake-up circuit in a dormant state
End.Wake-up circuit is used for the wake-up signal for receiving and recognizing vitro program controlled instrument transmitting, and has opening telecommunication circuit to be at
The function of working condition;
Hybrid coding circuit is opened when telecommunication circuit transmits electrocardiogram (ECG) data to program control instrument, and it is inputted gathers for ASIC
Electrocardiosignal and event flag from MCU, hybrid coding circuit by ecg information plus event flag position, check bit, rise
Beginning position and stop bit, export to communication code circuit;
Communication code circuit transmits electrocardiogram (ECG) data and the hardware information being stored in MCU, each in telecommunication circuit to program control instrument
Opened when the data such as kind parameter, battery status, data on file, it is inputted as the output of hybrid coding circuit and MCU phase
The signal of input is converted into communications codes by information code, is then output to transmitting tube by corresponding output serial ports, communication code circuit
On;
Transmitting tube telecommunication circuit to program control instrument transmit electrocardiogram (ECG) data and be stored in MCU hardware information, various parameters,
Opened when the data such as battery status, data on file, it inputs the output for communication code circuit, and the effect of transmitting tube is logical
The electric current crossed on control communication coil cut-offs, and is loaded into send to the data of program control instrument on communication coil.
A kind of control method of radio communication circuit structure applied to Implanted cardiac pacemaker, comprises the following steps:
1) data are exchanged:Using vitro program controlled instrument, constantly by external coil L and internal coil L coupling, to wireless
Telecommunication circuit sends specific wake-up signal;Wake-up signal is received into after radio communication circuit by internal coil L, successively
Module, amplifier module, hysteresis comparator module, waveform-shaping module and wake-up circuit module after filtering, will be entirely wireless
Telecommunication circuit is changed to wake-up states by resting state, while notifies internal MCU module;MCU module enters transmitting work in vivo
Pattern, MCU module pass sequentially through communication code module, transmitting tube module, internal coil L, pacemaker checking information are launched
Radio communication circuit module, after external coil L is received by vitro program controlled instrument, radio communication circuit module enters to be connect in vivo
Knock off operation mode;Program control instrument module is by the checking information received before successively via external coil L, internal coil L, filtering mould
Block, amplifier module, hysteresis comparator module, waveform-shaping module, decoding module are transmitted to MCU module, MCU module and received
Check information confirms correct and then is repeated once the above-mentioned checking procedure sent and received, if verification is errorless, communicates suitable
Profit is established, and otherwise radio communication circuit module revert to resting state after the wait of a period of time;
2) ECG Data Transmission Based:Module ASIC gathers the electrocardiogram (ECG) data from heart, then transmits to MCU module;MCU module
Stop the data transfer with radio communication circuit module, event flag produced according to the electrocardiogram (ECG) data received from module ASIC,
By the storage of event flag position into register;Electrocardiogram (ECG) data of the wireless communication module timing acquiring from module ASIC and come from
The event flag of MCU module, the electrocardiogram (ECG) data collected and event flag are passed through into hybrid coding module, into communication code mould
Block is compiled into communications codes, then by transmitting tube module loading to internal coil L, by being coupled with external coil L by external journey
Control instrument module receives, and completes the general transmitting procedure of electrocardiogram (ECG) data;
3) resting state:Electrocardiogram (ECG) data often sends certain number, and radio communication circuit module opens receiving path, receives and
From the synchronizing signal of program control instrument module, synchronizing signal out synchronizes really into synchronization module later from waveform-shaping module
Recognize, confirm successfully then to continue ECG Data Transmission Based mode of operation, otherwise radio communication circuit module enters dormancy mode of operation.
Compared with prior art, the present invention has advantages below:
The present invention provides a kind of application specific integrated circuit communication module applied to Implanted cardiac pacemaker, contains complete
Reception and transmission path, by directly being encoded, being decoded to the pulse of transmitting-receiving, meet the rate requirement of communication, be one
Cover low-power consumption, the scheme of low error rate.Under the pacemaker structure that ASIC and MCU cooperates, the telecommunication circuit in the present invention
Codec functions that module has, automatic wake-up function, it is automatic send the function such as electrocardiogram (ECG) data and synchronization check, greatly
Alleviate MCU work load, so as to the power consumption and the heating that inhibit MCU in outside program control instrument communication process well
Amount.
Further, Implanted cardiac pacemaker mainly includes electrode, special circuit (ASIC), microcontroller (MCU) and special
With functional modules such as radio communication circuits, wherein special circuit ASIC and radio communication circuit takes full custom ic to set
Meter, circuit structure is simple, compact-sized.It can be good at controlling power consumption and area, extend pacemaker service life, reduce
Monolithic chip cost.Circuit structure in the present invention realizes majority logic function by special circuit so that the hair of built-in MCU
Heat significantly reduces, and reduces patient's sense of discomfort.The circuit structure disclosure satisfy that following characteristics:Passing through the feelings of human body and titanium shell
Communication distance under condition with vitro program controlled instrument is more than 10cm;It is higher to external transmission data rate in vivo;The error code of telecommunication circuit
Rate is less than ten a ten thousandths;The stand-by power consumption of telecommunication circuit is extremely low;The operating power consumption of telecommunication circuit disclosure satisfy that pacemaker just
Normal requirements for life;At a temperature of 37 DEG C of fluid environment, continuous communiction 0.5 hour, titanium shell surface temperature, which rises, is less than 2 DEG C.
Further, transmitting procedure of the present invention is not against carrier wave, therefore receives, analog circuit end very simple with transmission process
And demodulation modulated signal is not needed, it is only necessary to recover waveform and control transmitting tube cut-offs.Therefore the circuit structure of the present invention
More simple, power consumption and area decline to a great extent, during work of the radio communication circuit structure under 0.35 μm of technique in the present invention
Maximum current be less than 50 μ A.
The control method of the present invention includes three kinds of working conditions:Exchange data, ECG Data Transmission Based and resting state;In vitro
Parameter preset can be transferred in the functional device to implant by program control instrument by telecommunication circuit;The functional device to implant
Hardware information, various parameters, battery status, data on file and the heart that can will be stored in by radio communication circuit in MCU
The ECG Data Transmission Based of dirty pacemaker special circuit detection is to vitro program controlled instrument.Control process traffic rate of the present invention is higher, knot
Structure is stable, and antinoise, interference performance are strong, can be good at the communication function demand for meeting Implanted cardiac pacemaker, and should
Structure can share majority logic functions of the MCU in communication process, reduce the caloric value of pacemaker system, while circuit knot
Structure is simple, low in energy consumption, extends battery life, reduces cost.
Brief description of the drawings
Fig. 1 is heretofore described radio communication circuit structural representation;
Fig. 2 is heretofore described hybrid coding circuit module coding rule schematic diagram;
Relation schematic diagrams of the Fig. 3 between heretofore described numeric data code and communications codes.
Embodiment
Implanted cardiac pacemaker requires continuous firing more than 10 years in human body with battery powered, for circuit
Power consumption it is very sensitive, therefore the circuit structure provided in the present invention is designed and realized using the mode of low-power consumption.The present invention
In fully functional and circuit structure it is simple, can be good at controlling power consumption and area, extend pacemaker service life, subtract
Small monolithic chip cost.Circuit structure in the present invention realizes majority logic function by special circuit so that built-in MCU
Caloric value significantly reduce, reduce patient's sense of discomfort.
Circuit structure in the present invention also passes through suppression while realization can be communicated with larger data transmission rate
Noise and clutter processed, control the bit error rate in communication process.Circuit structure in the present invention is a stable communication state
Machine.
Below in conjunction with the accompanying drawings, the present invention is described in further detail.What is highlighted in the following description is circuit
Key effect of the modules played in overall circuit configuration, is by retouching for the illustration of circuit communication mode
State circuit working method further to remark additionally the function of circuit structure, but be not the emphasis of the present invention, therefore herein simultaneously
All communications status will not be fully described by.
Referring to Fig. 1, a kind of radio communication circuit structure applied to Implanted cardiac pacemaker of the invention includes channel radio
Believe circuit 01.The radio communication circuit 01 includes filtration module 010, amplifier module 011, hysteresis comparator module 012, ripple
Shape Shaping Module 013, synchronization module 014, decoding module 015, wake-up circuit module 016, transmitting tube module 017, communication code
Module 018, hybrid coding module 019 and internal coil L1.
This radio communication circuit usually in a dormant state, the arousal function intermodule of radio communication circuit under resting state
Open to having a rest property, to intercept whether vitro program controlled instrument has wake-up to instruct, the power consumption of this mode of operation is very low, in 0.35 μm of work
Electric current is less than 10nA under the conditions of skill and 32K crystal oscillator clocks.
When doctor needs to establish communication to exchange data, using vitro program controlled instrument 2, constantly pass through external coil
L2 and internal coil L1 coupling, specific wake-up signal is sent to radio communication circuit 01.Wake-up signal is by internal coil L1
Receive into after radio communication circuit 01, successively module 010, amplifier module 011, hysteresis comparator module after filtering
012nd, waveform-shaping module 013 and wake-up circuit module 016, whole radio communication circuit 01 is changed to wake-up by resting state
State, while notify internal MCU module 03.Next MCU module 03 enters transmitting mode of operation in vivo, detailed process is MCU
Module 03 passes sequentially through communication code module 018, transmitting tube module 017, internal coil L1, and pacemaker checking information is launched
Radio communication circuit module 01, after external coil L2 is received by vitro program controlled instrument 2, radio communication circuit module 01 enters
Mode of operation is received in vivo, and program control instrument module 2 is by the checking information received before successively via external coil L2, internal coil
L1, filtration module 010, amplifier module 011, hysteresis comparator module 012, waveform-shaping module 013, decoding module 015 pass
Transport to MCU module 03, MCU module 03 receives check information and confirms correct and then be repeated once above-mentioned send and receive
Checking procedure, if verification is errorless, communicate smoothly establish, otherwise radio communication circuit module 01 a period of time wait it
After revert to resting state.
Wireless communication module 01 is controlled in the mode of operation for waking up and smoothly establishing after communication by MCU module 03,
And MCU module 03 allows wireless communication module 01 which kind of mode of operation be in, then the program control instrument module 2 that is received by MCU module 03
The mode control instruction that sends determines.Wireless communication module 01 1 shares three kinds of working methods, including sends Working mould in vivo
Formula, mode of operation and ECG Data Transmission Based mode of operation are received in vivo, due to the control of the mode of operation of wireless communication module 01
Carried out by MCU module 03, so sending and receiving in vivo under mode of operation in vivo, performed by wireless communication module 01
Function and do not had any different in awakening phase transfer check information, equivalent to one MCU module 03 to vitro program controlled instrument module 2
Data transfer and the path of parsing, wherein receiving mode of operation in vivo is equal to the verification that vitro program controlled instrument module 2 will receive
Information is sent to the course of work of MCU module 03, and transmission mode of operation is equivalent in vivo is sent to check information with MCU module 03
The course of work of vitro program controlled instrument module 2.
If the desired vivo devices circuit module 0 of doctor outwards transmits electrocardiogram (ECG) data, by receiving work in vivo
Pattern sends to MCU module 03 and instructed, the mode of operation of switching radio communication circuit module 01 to ECG Data Transmission Based Working mould
Formula.Under this mode of operation, module ASIC 02 gathers the electrocardiogram (ECG) data from heart 1, then transmits to MCU module 03;MCU module
03 stops the data transfer with radio communication circuit module 01, and event is produced according to the electrocardiogram (ECG) data received from module ASIC 02
Mark, by the storage of event flag position into register;Electrocardio number of the timing acquiring of wireless communication module 01 from module ASIC 02
According to the event flag from MCU module 03, by the electrocardiogram (ECG) data collected and event flag by hybrid coding module 019 by
Check bit, start bit and stop bit are added according to the rule set, is compiled into communications codes into communication code module 018, then pass through
Cross transmitting tube module 017 to be loaded on internal coil L1, received by being coupled with external coil L2 by vitro program controlled instrument module 2
Arrive, complete the general transmitting procedure of electrocardiogram (ECG) data.Electrocardiogram (ECG) data often sends certain number, and radio communication circuit module 01 is opened and connect
Path is received, receives the synchronizing signal from program control instrument module 2, the reception of synchronizing signal is different from receiving mode of operation in vivo, together
Step signal out synchronizes confirmation into synchronization module 014 later from waveform-shaping module 013, confirms successfully then to continue electrocardio
Data transfer mode of operation, otherwise radio communication circuit module 01 enter dormancy mode of operation.
In the case where wireless communication module arbitrarily needs to receive data cases, the module of opening includes:
The coil L1 in vivo, it is to be coupled the data on external coil L2 by mutual inductance that it, which is acted on, there is provided to follow-up electricity
Road;
The filtration module 010, its effect is the electric signal on receiving body interior loop L1, and filters out other and be coupled to
Clutter on coil;
The amplifier module 011, it, which is acted on, receives the signal after module 010 after filtering, by signal amplification and
Differential signal is converted to by single-ended signal, it is therefore an objective to the signal decayed after filtering is subjected to pre-amplification, enables wireless communication module
It is enough also to receive the signal transmitted by vitro program controlled instrument in as far as possible remote distance, meet the requirement of communication distance;
The hysteresis comparator module 012, its act on be receive by amplifier module 011 export differential signal and
It is converted into single-ended data signal, it is therefore an objective to complete conversion of the analog quantity to digital quantity, while hysteresis comparator regards specifically
Certain amount of hysteresis is introduced depending on signal intelligence, can be very good to mask noise signal, prevent error code, lifts anti-interference energy
Power;
The waveform-shaping module 013, its act on be receive the output of hysteresis comparator module 012 there is dutycycle to lack of proper care
Data signal, and it is converted into the data signal of standard dutycycle.
Under ECG Data Transmission Based mode of operation, except to open above-mentioned any circuit for receiving data cases and needing to open
Outside module, synchronization module 014 is also opened, it is periodically to receive the synchronizing information that vitro program controlled instrument is sent that it, which is acted on, is connect
Then wireless communication module continues ECG Data Transmission Based mode of operation to harvest work(, reception failure then wireless communication module from electrocardiogram (ECG) data
Transmission mode of operation is exited to resting state.
Receive in vivo under mode of operation, except to open above-mentioned any circuit module for receiving data cases and needing to open
Outside, decoding module 015 is also opened, its effect is by the data signal after the shaping of waveform shaping circuit module 013
Numeric data code is decoded into from communications codes.
Dormancy is in wireless communication module to treat to need to beat except opening above-mentioned any data cases that receive under wake-up states
Outside the circuit module opened, the wake-up circuit module 016 is also opened, its effect is to intercept wake-up signal, be successfully be detected
Wake-up signal then wake on wireless telecommunication circuit.
In the case where wireless communication module arbitrarily needs to send data cases, the module of opening includes:
The communication code module 018, it is that will arbitrarily input to change to logical into the signal of the module from numeric data code that it, which is acted on,
Believe code, and communications codes are exported to transmitting tube module 017;
The transmitting tube module 017, it is that the communications codes after communication code module 018 encodes are loaded into body to work
On interior loop L1;
The coil L1 in vivo, it is the electric signal for receiving transmitting tube module 017 that it, which is acted on, by coil mutual inductance by signal coupling
Close on external coil L2.
Under ECG Data Transmission Based pattern, except to open it is above-mentioned it is any send needed under data cases the module opened it
Outside, it is also necessary to open hybrid coding module 019, it is the electrocardiogram (ECG) data and MCU module that will be collected from module ASIC 02 that it, which is acted on,
03 event flag collected is integrated, and adds start bit, stop bit and check code, is then forwarded to communication code module 018,
The coding rule schematic diagram of the hybrid coding module 019 is as shown in Figure 2.
The transmitting tube module 017 can be bipolar transistor or MOSFET.
The filtration module 010 can be that passive filtering structure can also be active power filtering structure.
Relation between numeric data code and communications codes as shown in Figure 3, by such conversion, by the low and high level of numeric data code
Width information is converted into being carried on the information on single direction triggering edge, so as to impulse waveform shape caused by specific inductive
Shape does not interfere with the signal of parsing, so can be good at avoiding error caused by signal resolution in communication process.
The coil L1 in vivo, is the special-shaped air core coil along institute's coiling on the inside of Implanted cardiac pacemaker titanium shell.
In the present invention, due to performance and technique, it can not be realized in the form of being integrated on chip.
The wireless communication module 01 is real in the form of full custom application specific integrated circuit in addition to internal coil L1
It is existing, but this is not limited to, proposed by the present invention is the system architecture of a wireless communication module, and the scope of this structure is equally wrapped
Include in the integrated circuit realized by other forms.Depending on the performance of integrated circuit technology, the transmitting tube module 017,
Filtration module 010 can also select to realize in the form of discrete device.
The maximum transmission rate of heretofore described radio communication circuit determined by the clock signal of special circuit,
Radio communication circuit under 32K crystal oscillator clock signals to the maximum transmission rate of program control instrument be 8.192kbps.
The present invention one is different from other and is characterised by suitable for Implanted cardiac pacemaker radio communication circuit structure
Transmitting procedure is not against carrier wave, therefore reception and transmission process are very simple, and analog circuit end does not need demodulation modulation letter simultaneously
Number, it is only necessary to recover waveform and control transmitting tube cut-offs.Therefore the circuit structure of the present invention is more simple, power consumption and area are big
Width declines, and maximum current during work of the radio communication circuit structure under 0.35 μm of technique in the present invention is less than 50 μ A.
In summary, the radio communication circuit structured communication speed proposed in the present invention is higher, Stability Analysis of Structures, antinoise,
Interference performance is strong, can be good at the communication function demand for meeting Implanted cardiac pacemaker, and the structure can share MCU
Majority logic function in communication process, the caloric value of pacemaker system is reduced, while circuit structure is simple, low in energy consumption,
Battery life is extended, reduces cost.
Claims (8)
1. a kind of radio communication circuit structure applied to Implanted cardiac pacemaker, it is characterised in that including radio communication electricity
Road (01), the radio communication circuit (01) include filtration module (010), amplifier module (011), hysteresis comparator module
(012), waveform-shaping module (013), synchronization module (014), decoding module (015), wake-up circuit module (016), transmitting tube
Module (017), communication code module (018), hybrid coding module (019) and internal coil L1;Vitro program controlled instrument (2) passes through
External coil L2 and internal coil L1 is of coupled connections, and internal coil L1 is sequentially connected filtration module (010), amplifier module
(011), hysteresis comparator module (012), waveform-shaping module (013), waveform-shaping module (013) pass through synchronization module respectively
(014), decoding module (015) and wake-up circuit module (016) are connected with MCU module (03);MCU module (03) passes sequentially through logical
Believe coding module (018), transmitting tube module (017), internal coil L1, MCU messages are launched into radio communication circuit module
(01), transmitted through external coil L2 to vitro program controlled instrument (2);Module ASIC (02) is connected collection electrocardiogram (ECG) data with from heart (1),
And transmit to MCU module (03);Wireless communication module (01) collection module ASIC (02) and MCU module (03) electrocardiogram (ECG) data according to
It is secondary to be connected by hybrid coding module (019) with communication code module (018).
2. the radio communication circuit structure according to claim 1 applied to Implanted cardiac pacemaker, it is characterised in that
Described transmitting tube module (017) is bipolar transistor or MOSFET.
3. the radio communication circuit structure according to claim 1 applied to Implanted cardiac pacemaker, it is characterised in that
Described filtration module (010) is passive filtering structure or active power filtering structure.
4. the radio communication circuit structure according to claim 1 applied to Implanted cardiac pacemaker, it is characterised in that
Coil L1 is the special-shaped air core coil along institute's coiling on the inside of Implanted cardiac pacemaker titanium shell inside described.
5. the radio communication circuit structure according to claim 1 applied to Implanted cardiac pacemaker, it is characterised in that
Described wireless communication module (01) is in addition to internal coil L1, using the form of integrated circuit.
6. the radio communication circuit structure according to claim 1 applied to Implanted cardiac pacemaker, it is characterised in that
For described radio communication circuit (01) when using 0.35 μm of technique, maximum current during work is less than 50 μ A.
7. the radio communication circuit structure according to claim 1 applied to Implanted cardiac pacemaker, it is characterised in that
Described radio communication circuit (01) uses 32K crystal oscillator clock signals, maximum transmission rate of the radio communication circuit to program control instrument
For 8.192kbps.
A kind of 8. controlling party of the radio communication circuit structure as claimed in claim 1 applied to Implanted cardiac pacemaker
Method, it is characterised in that comprise the following steps:
1) data are exchanged:Using vitro program controlled instrument (2), constantly pass through external coil L2 and internal coil L1 coupling, Xiang Wu
Line telecommunication circuit (01) sends specific wake-up signal;Wake-up signal is received into radio communication circuit by internal coil L1
(01) after, module (010), amplifier module (011), hysteresis comparator module (012), waveform shaping mould after filtering successively
Block (013) and wake-up circuit module (016), whole radio communication circuit (01) is changed to wake-up states by resting state, together
MCU module (03) in Shi Tongzhi bodies;MCU module (03) enters transmitting mode of operation, MCU module (03) in vivo and passes sequentially through communication
Coding module (018), transmitting tube module (017), internal coil L1, launch radio communication circuit mould by pacemaker checking information
Block (01), after external coil L2 is received by vitro program controlled instrument (2), radio communication circuit module (01) enters to be received in vivo
Mode of operation;Program control instrument module (2) is by the checking information received before successively via external coil L2, internal coil L1, filter
Ripple module (010), amplifier module (011), hysteresis comparator module (012), waveform-shaping module (013), decoding module
(015) transmit to MCU module (03), MCU module (03) receives check information and confirms correct and then be repeated once above-mentioned hair
The checking procedure sent and received, if verification is errorless, communicates and smoothly establish, otherwise radio communication circuit module (01) is at one section
Resting state is revert to after the wait of time;
2) ECG Data Transmission Based:Electrocardiogram (ECG) data of module ASIC (02) collection from heart (1), then transmit to MCU module (03);
MCU module (03) stops the data transfer with radio communication circuit module (01), according to the heart received from module ASIC (02)
Electric data produce event flag, by the storage of event flag position into register;Wireless communication module (01) timing acquiring comes from
The electrocardiogram (ECG) data of module ASIC (02) and the event flag from MCU module (03), by the electrocardiogram (ECG) data collected and event mark
Note passes through hybrid coding module (019), and communications codes are compiled into communication code module (018), then by transmitting tube module
(017) it is loaded on internal coil L1, is received by being coupled with external coil L2 by vitro program controlled instrument module (2), completes the heart
The general transmitting procedure of electric data;
3) resting state:Electrocardiogram (ECG) data often sends certain number, and radio communication circuit module (01) opens receiving path, receives and
Synchronizing signal from program control instrument module (2), synchronizing signal out enter synchronization module later from waveform-shaping module (013)
(014) confirmation is synchronized, confirms successfully then to continue ECG Data Transmission Based mode of operation, otherwise radio communication circuit module (01)
Into dormancy mode of operation.
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US20030078631A1 (en) * | 2001-10-23 | 2003-04-24 | Medtronic, Inc. | Network communications arrangement for IMD programming units |
CN1864763A (en) * | 2006-03-31 | 2006-11-22 | 西安交通大学 | A remote detection device for implanted heart pacemaker and bidirectional data transmission method |
CN105892317A (en) * | 2016-03-31 | 2016-08-24 | 创领心律管理医疗器械(上海)有限公司 | Implantable medical device, data outputting and receiving methods thereof and communication mechanism |
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Publication number | Priority date | Publication date | Assignee | Title |
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US20030078631A1 (en) * | 2001-10-23 | 2003-04-24 | Medtronic, Inc. | Network communications arrangement for IMD programming units |
CN1864763A (en) * | 2006-03-31 | 2006-11-22 | 西安交通大学 | A remote detection device for implanted heart pacemaker and bidirectional data transmission method |
CN105892317A (en) * | 2016-03-31 | 2016-08-24 | 创领心律管理医疗器械(上海)有限公司 | Implantable medical device, data outputting and receiving methods thereof and communication mechanism |
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