CN107362310A - It is a kind of to be used to repair Baicao Fuyanqing preparation of vagina environment and preparation method thereof - Google Patents
It is a kind of to be used to repair Baicao Fuyanqing preparation of vagina environment and preparation method thereof Download PDFInfo
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Abstract
The present invention provides a kind of Baicao Fuyanqing preparation for being used to repair vagina environment, belongs to field of medicine preparations.The Baicao Fuyanqing preparation, is made up of the raw material of following parts by weight：50~80 parts of kuh-seng, 15~40 parts of the tuber of stemona, 15~40 parts of frutus cnidii, 15~40 parts of hairyvein agrimony, 15~40 parts of folium callicarpae pedunculatae, 0.5~2.0 part of alum, 0.1~2.0 part of borneol, 0.5~2.0 part of camphor, 1~15 part of boric acid, 220~350 parts of glycerine, 80~110 parts of gelatin.The Baicao Fuyanqing preparation realizes re-establishing for the intravaginal ecological balance, controls inflammation.Meanwhile this Baicao Fuyanqing preparation is prepared using Chinese herbal medicine, effectively prevent the side effect and adverse reaction of antibiotic.
Description
Technical field
The present invention relates to field of medicine preparations, more particularly to a kind of Baicao Fuyanqing system for being used to repair vagina environment
Agent and preparation method thereof.
Background technology
Vagina is a complicated Tiny ecosystem system, by the anatomical structure of vagina, Tiny ecosystem flora, local immunity and
The endocrine metabolic diseases function of body collectively constitutes.The morbidity of the common gynecological diseases such as vaginitis, cervicitis or cervical erosion, frequently-occurring disease
Mechanism is how relevant with vagina environment imbalance.Normal estrogen level is kept in vivo, and vagina epithelium is continuous and complete, cloudy
The immunologic function that the local immune system in road is brought into normal play, reside in holding life between the flora based on the Bacillus acidi lactici of intravaginal
State balances, and is the principal element for making vaginal homeostasis, and one of link is destroyed the generation that can cause inflammation.
The normal microecological balance for colonizing in intravaginal（Flora）The beneficial bacteriums such as imbalance, ability of Lactobacillus in human vagina are reduced and it
His bacterium amount reproduction, anaerobic bacteria breeding produce amine substance simultaneously, and alkalize vagina, increases vaginal fluid and has stink.
Therefore the normal vaginal flora balance of regulation patient is to repair the key of vagina environment.Colpitis often results in intravaginal mucous membrane
Hyperemia, superficial ulcer, middle severe are rotten to the corn, and severe patient may occur in which adhesions of vagina, pyrocolpos or pyometra, the above-mentioned surface of a wound and pole
Easily sticked by germ, breed, cause the depth development of inflammation process.
The treatment for colpitis uses anti-inflammatory treatment more in the prior art, and in the market correlation medicine is with bactericidal antiphlogistic
For the purpose of, its result destroys the balance of normal flora in vagina, is unfavorable for intravaginal microbe survival.Meanwhile market
The interior environment of vagina itself is destroyed while upper gynaecology is with product largely using antibiotic and bactericide to treat vaginitis,
Cause therapeutic effect poor, the normal recurrent exerbation of the state of an illness, stubbornness is difficult to effect a radical cure.
The content of the invention
One of goal of the invention of the present invention is, in view of the above-mentioned problems, providing a kind of hundred grass for being used to repair vagina environment
The scorching clear preparation of woman, promotes the fast quick-recovery and propagation of the vagina probiotics such as Bacillus acidi lactici, realizes the intravaginal ecological balance again
Establish, and can significantly repair vagina mucosa damage or ulcer healing, promote vagina mucosa to produce the anti-infectious immunity factor, control
Inflammation, reduce recurrence.Meanwhile this Baicao Fuyanqing preparation is prepared using Chinese herbal medicine, avoid anti-using Ornidazole and Tinidazole etc.
Raw element, effectively prevent side effect and adverse reaction.
To reach above-mentioned purpose, the technical solution adopted in the present invention is：
A kind of Baicao Fuyanqing preparation for being used to repair vagina environment, is made up of the raw material of following parts by weight：
50~80 parts of kuh-seng, 15~40 parts of the tuber of stemona, 15~40 parts of frutus cnidii, 15~40 parts of hairyvein agrimony, 15~40 parts of folium callicarpae pedunculatae, in vain
0.5~2.0 part of alum, 0.1~2.0 part of borneol, 0.5~2.0 part of camphor, 1~15 part of boric acid, 220~350 parts of glycerine, gelatin 80
~110 parts.
As a kind of preferable scheme, the Baicao Fuyanqing preparation is made up of the raw material of following parts by weight：Kuh-seng 60~68
Part, 25~35 parts of the tuber of stemona, 25~35 parts of frutus cnidii, 25~35 parts of hairyvein agrimony, 25~35 parts of folium callicarpae pedunculatae, 0.8~1.2 part of alum,
0.3~1.0 part of borneol, 0.8~1.2 part of camphor, 3~8 parts of boric acid, 250~300 parts of glycerine, 90~100 parts of gelatin.
As a kind of preferable scheme, the Baicao Fuyanqing preparation is made up of the raw material of following parts by weight：64 parts of kuh-seng, hundred
32 parts of portion, 32 parts of frutus cnidii, 32 parts of hairyvein agrimony, 32 parts of folium callicarpae pedunculatae, 1.0 parts of alum, 0.5 part of borneol, 1 part of camphor, 6 parts of boric acid,
260 parts of glycerine, 95 parts of gelatin.
As a kind of preferable scheme, the Baicao Fuyanqing preparation is vagina external preparation.
As a kind of preferable scheme, the Baicao Fuyanqing preparation is suppository.
Another goal of the invention of the present invention is, in view of the above-mentioned problems, providing a kind of hundred grass for being used to repair vagina environment
The preparation method of the scorching clear preparation of woman, vagina, convenient administration and drug action are acted on by the way of external suppository.
To reach above-mentioned purpose, the technical solution adopted in the present invention is：
A kind of Baicao Fuyanqing formulation preparation method for being used to repair vagina environment, comprises the following steps：
（1）Kuh-seng, the tuber of stemona, frutus cnidii, hairyvein agrimony and folium callicarpae pedunculatae are weighed, is added water to cook three times, first and second time is each 2~3 hours,
1~2 hour for the third time, decocting liquid three times is merged and filtered to get filtrate, the filtrate is condensed into clear cream；Then to the clear cream
In plus 95% ethanol until alcohol content stands 24 hours, takes supernatant up to untill 60%, filtering；Finally by the supernatant after filtering
Recovery ethanol is simultaneously condensed into thick paste, standby.
（2）Glycerine is taken, is heated to 115 DEG C~120 DEG C, adds gelatin, is stirred continuously to gel solubilizing, formation glycerin gelatine
Matrix, alum, boric acid are then ground into fine powder, and added in glycerol gelatin matrix, be eventually adding after thick paste stirs and stop
Only heat.
（3）Borneol is dissolved with a small amount of ethanol and camphor obtains mixed liquor, and institute is added when glycerol gelatin matrix is cooled into 90 DEG C
Mixed liquor is stated, and is stirred, last moulding finished product.
As a kind of preferable scheme, step（1）In, at 25 DEG C, concentrate the filtrate to relative density for 1.08~
1.10 clear cream.
As a kind of preferable scheme, step（1）In, at 25 DEG C, supernatant is reclaimed into ethanol and is concentrated into relatively close
Spend the thick paste for 1.30 ~ 1.35.
Due to using above-mentioned technical proposal, the invention has the advantages that：
1. Baicao Fuyanqing preparation of the present invention, using the comprehensive function of various Chinese herbal medicines, generate significant collaboration and control
Therapeutic effect.First, the fast quick-recovery and propagation of the vagina probiotics such as Bacillus acidi lactici can be promoted, safeguard normal intravaginal pH value with
Bacterial community, realize re-establishing for the intravaginal ecological balance.Secondly, local necrosis tissue loss can be accelerated, significantly repaired cloudy
Road mucosa injury or ulcer healing, promote position granulation tissue growth, regeneration, to prevent the sticking of pathogenic bacteria, breed, from root
Inflammation process is blocked on this.Again, vagina mucosa can be irritated and produce a large amount of anti-infectious immunity factor IgA, so as to improve intravaginal
Effects on local immunological functions, suppress the existence of pathogenic bacteria.So as to improve vagina environment comprehensively, reach the purpose of radical cure.
2. the Baicao Fuyanqing preparation of the present invention is prepared only with Chinese herbal medicine, avoid using Western medicine such as Tinidazoles.Avoid
The side effect and the resistance to the action of a drug that Western medicine is brought, and can effectively effect a radical cure gynecological disease.
3. the raw material that the Baicao Fuyanqing preparation of the present invention uses is easily obtained, the quality of production is easily controlled, in addition in itself
The cost of medicine is relatively low, need not also use special administration device, therefore be easier to popularization and application.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
Embodiment 1
A kind of Baicao Fuyanqing preparation for being used to repair vagina environment, is made from the following raw materials in parts by weight：64 parts of kuh-seng, hundred
32 parts of portion, 32 parts of frutus cnidii, 32 parts of hairyvein agrimony, 32 parts of folium callicarpae pedunculatae, 1.0 parts of alum, 0.5 part of borneol, 1 part of camphor, 6 parts of boric acid,
260 parts of glycerine, 95 parts of gelatin.
Preparation method comprises the following steps：
（1）Kuh-seng, the tuber of stemona, frutus cnidii, hairyvein agrimony and folium callicarpae pedunculatae are weighed, is added water to cook three times, first and second time is each 2 hours, and the 3rd
Secondary 1 hour, decocting liquid three times is merged and filtered to get filtrate.Then, relative density is concentrated the filtrate to as 1.08~1.10（25
℃）Clear cream.
Then into the clear cream plus 95% ethanol is until alcohol content standing 24 hours, takes supernatant, mistake up to untill 60%
Filter.Then, supernatant is reclaimed into ethanol and is concentrated into relative density as 1.30 ~ 1.35（25℃）Thick paste.It is standby.
（2）Glycerine is taken, is heated to 115 DEG C~120 DEG C, adds gelatin, is stirred continuously to gel solubilizing, formation glycerin gelatine
Matrix, alum, boric acid are then ground into fine powder, and added in glycerol gelatin matrix, be eventually adding after thick paste stirs and stop
Only heat.
（3）Borneol is dissolved with a small amount of ethanol and camphor obtains mixed liquor, and institute is added when glycerol gelatin matrix is cooled into 90 DEG C
Mixed liquor is stated, and is stirred, suppository is made in last moulding.
Embodiment 2
A kind of Baicao Fuyanqing preparation for being used to repair vagina environment, is made from the following raw materials in parts by weight：60 parts of kuh-seng, hundred
30 parts of portion, 30 parts of frutus cnidii, 35 parts of hairyvein agrimony, 35 parts of folium callicarpae pedunculatae, 0.8 part of alum, 0.8 part of borneol, 1.0 parts of camphor, boric acid 8
Part, 300 parts of glycerine, 100 parts of gelatin.
Preparation method comprises the following steps：
（1）Kuh-seng, the tuber of stemona, frutus cnidii, hairyvein agrimony and folium callicarpae pedunculatae are weighed, is added water to cook three times, first and second time is each 2.5 hours, the
1.5 hours three times, decocting liquid three times is merged and filtered to get filtrate.Then, relative density is concentrated the filtrate to as 1.08~1.10
（25℃）Clear cream.
Then into the clear cream plus 95% ethanol is until alcohol content standing 24 hours, takes supernatant, mistake up to untill 60%
Filter.Then, supernatant is reclaimed into ethanol and is concentrated into relative density as 1.30 ~ 1.35（25℃）Thick paste.It is standby.
（2）Glycerine is taken, is heated to 115 DEG C~120 DEG C, adds gelatin, is stirred continuously to gel solubilizing, formation glycerin gelatine
Matrix, alum, boric acid are then ground into fine powder, and added in glycerol gelatin matrix, be eventually adding after thick paste stirs and stop
Only heat.
（3）Borneol is dissolved with a small amount of ethanol and camphor obtains mixed liquor, and institute is added when glycerol gelatin matrix is cooled into 90 DEG C
Mixed liquor is stated, and is stirred, last moulding finished product.
Embodiment 3
A kind of Baicao Fuyanqing preparation for being used to repair vagina environment, is made from the following raw materials in parts by weight：70 parts of kuh-seng, hundred
20 parts of portion, 20 parts of frutus cnidii, 20 parts of hairyvein agrimony, 20 parts of folium callicarpae pedunculatae, 0.8 part of alum, 0.8 part of borneol, 1.0 parts of camphor, boric acid 8
Part, 300 parts of glycerine, 90 parts of gelatin.
Preparation method is the same as embodiment 1.
Experimental example：The effect of Chinese herbal and crude drugs preparations for repairing vagina environment, is studied.
The infection of rat genital tract is caused using different pathogenic microorganisms, the Chinese herbal medicine system then prepared with embodiment 1
Agent carries out local treatment, observes it and suppresses pathogenic microorganism, and to local vaginal mucosal barrier protective effect, mucosal immunity work(
The facilitation of energy, it is therefore intended that prove that Chinese herbal and crude drugs preparations is used for the effect of vaginitis disease prevention and cure under women.
Materials and methods
Experimental animal：SD Inbred Rat Strains, SPF levels, female.12 week old.Body weight 280.0-320.0g.It is purchased from Peking University's medical science
Portion's Experimental Animal Center.Animal credit number：SCXK-（Capital）2011-0012.Animal is placed in 12h/12h light and shade alternate environments, from
By feeding.All zoopery operations are performed by Beijing management of laboratory animal regulations.
Tested material：Baicao Fuyanqing preparation prepared by embodiment 1.
Positive control medicine：Nifuratel vaginal tablets（MACMIROR vaginal tablets, trade name：Macmiror
250.Specification：250mg/ grains.
The manufacture of model：
1. the inbred strais SD rats that will be purchased, per 4, cage, sub-cage rearing.Animal feeding condition is：22 ± 2 DEG C, humidity：45-60%,
12 hours light and shade alternatings.Ad lib.After Animal adaptability is raised 1 week, start to manufacture animal model, comprise the following steps that and state.
Following group is randomly divided into 2. mouse is divided into, such as table 1：
1. solvent control group（vehicle control group）：8.Every is subcutaneously injected 0.2ml food oils daily, continuously
5 days." solvent control group " in items research shares；
2. compound infection model group（Candida albicans+Gardnerella+Trichomonas）Give subcutaneous rat note
Penetrate Estradiol Valerate（Estradiol Valerate）Finish, dosage are：0.5mg/100g/0.2ml oil s.c., continuous 5
My god.Start within 6th day to give rat vagina inoculation compound pathogenic microorganism（Concentration is that 0.1ml contains every kind of pathogenic microorganism 104
）, continuous 7 days.
3. the rat model manufacture of positive control drug group and Baicao Fuyanqing preparation for treating group is same " compound infection model group ".
The anti-compound infection group of table 1
Drug therapy（Specific such as table 2）
1. after various infection models manufacture successfully（Vagina has obvious secretion to flow out, and vaginal vulva is red and swollen, and has serious different
Taste）, carry out experimental therapy.
2. the determination of Baicao Fuyanqing formulation dosage：People is with dosage：4g/ is daily/everyone.Body weight is based on 70kg
Calculate.Conversion is measured according to the medication of human body and rat（International standard, U.S. FDA are determined）, the dosage of rat is about
6 times of human body.Dosage is defined below：
4000mg/ days/everyone ÷ 70kg × 6.0=342.86mg/kg.Using this dosage as middle dosage.
Low dosage：342.86÷2=171.43 mg/kg
Middle dosage：342.86 mg/kg
High dose：342.86×2=685.72 mg/kg
3. the determination of quantity of solvent：
Baicao Fuyanqing preparation 4g/ is each, is 3.5ml after dissolving.Counted using rat average weight as 250g, solvent volume is：
Low dosage：(171.43 mg/kg ÷1000×250g)×4.0÷3.5=49.98=50µl；
Middle dosage：(342.86 mg/kg ÷1000×250g)×4.0÷3.5=100µl；
High dose：(685.72 mg/kg ÷1000×250g)×4.0÷3.5=200µl；
4. the dosage of positive control drug determines；
The positive control drug of anti-compound infection type vaginitis is：MACMIROR vaginal tablets （Nifuratel vagina
Piece）:People is 250mg/tablets/ days with dosage, and body weight is based on average 70kg.Human body is with rat dose lonvestion coefficient
6.0, then the dosage of the positive control drug of rat be：
250mg/ days/everyone ÷ 70kg × 6.0=21.42mg/kg.Average out to 250g rat dosage is 5.36mg/
250g；
The anti-compound infection group of table 2.
Interpretation of result
After treatment end, intravaginal juice and cast-off cells are collected.Every rat gathers three times respectively, is enriched with each sample
Amount.A part of sample, for extracting the tRNA in sample, the analysis of ability of Lactobacillus in human vagina is determined by PCR；A part is used
Analyzed in the immune factor to vaginal secretion；Another part is used to carry out fluidic cell quantitative analysis.In addition, separating animal's
Vagina tissue, after histotomy, dye fixed analysis.
As a result show
By being shown to the pathological analysis of vagina tissue, in multi-infection vaginitis model, vagina mucosa desquamation,
Apoptosis even necrosis, vagina mucosa layer is significantly thinning；It is significantly congested under epidermis；The visible intensive fibroblast of submucous tissue
Propagation, inflammatory cell infiltration, lymphadenoid lymphocyte aggregation group.In vaginal canal and the visible substantial amounts of cause of disease of submucosa
Body（Trichomonas vaginalis, Gardnerella）.After the Baicao Fuyanqing preparation for treating of low dosage, middle dosage and high dose, epidermis
Significantly recover；It is congested under mucous membrane significantly to mitigate.In vaginal canal and SM pathogen significantly reduces.Through Chi-Square
Test Chi-square Tests, P ＜ 0.05.
By being separated to vagina mucosa top layer and cast-off cells, after the cleaning of steril cell nutrient solution, fluidic cell is carried out
Analysis display, vagina infection caused by different pathogens, can make vagina mucosa cell detachment, and apoptosis is until necrosis.It is dead thin
Born of the same parents significantly increase, dead in the cell to come off after the Baicao Fuyanqing preparation for treating of low dosage, middle dosage and high dose
Substantially reduced with the epidermal cell of apoptosis.Through statistical test, P ＜ 0.05 ~ 0.001.
By producing anti-infectious immunity factor IgA elisa assay to vagina mucosa, as a result show, by bacterium, fungi,
And trichomonad, individually or in the infection model of mixing induced rat, its vagina mucosa secretion IgA is substantially reduced.And low dosage, middle dose
After the Baicao Fuyanqing preparation for treating of amount and high dose, rat model vagina IgA level can be significantly improved, P ＜ 0.05 ~
0.001。
Bacillus acidi lactici is the flora for maintaining intravaginal normal microenvironment, and we pass through the master to ability of Lactobacillus in human vagina
Represent flora to be analyzed, analyzed and identified, as a result shown, various diseases by carrying out RT-PCR to the 16SrRNA of Bacillus acidi lactici
After pathogen infection, its Bacillus acidi lactici substantially reduces.And after low dosage, middle dosage and high dose Baicao Fuyanqing preparation for treating, energy
It is enough significantly to recover ability of Lactobacillus in human vagina flora.
Conclusion
Chinese herbal and crude drugs preparations of the present invention can effectively from increase Bacillus acidi lactici flora, improve immunologic function and promotion organization more
It is raw etc. to repair vagina environment, so as to diminish inflammation, reach the purpose of radical cure.
The equal change or modification change completed under technical spirit suggested by all present invention of described above, all should belong to
It is the detailed description for being directed to the present invention preferably possible embodiments that the present invention, which is contained, but embodiment is not limited to the special of the present invention
Sharp application range, lid the scope of the claims.
Claims (8)
1. a kind of Baicao Fuyanqing preparation for being used to repair vagina environment, it is characterised in that by the raw material system of following parts by weight
Into：
50~80 parts of kuh-seng, 15~40 parts of the tuber of stemona, 15~40 parts of frutus cnidii, 15~40 parts of hairyvein agrimony, 15~40 parts of folium callicarpae pedunculatae, in vain
0.5~2.0 part of alum, 0.1~2.0 part of borneol, 0.5~2.0 part of camphor, 1~15 part of boric acid, 220~350 parts of glycerine, gelatin 80
~110 parts.
2. the Baicao Fuyanqing preparation according to claim 1 for being used to repair vagina environment, it is characterised in that by following
The raw material of parts by weight is made：60~68 parts of kuh-seng, 25~35 parts of the tuber of stemona, 25~35 parts of frutus cnidii, 25~35 parts of hairyvein agrimony, Japanses beauty-berry
25~35 parts of leaf, 0.8~1.2 part of alum, 0.3~1.0 part of borneol, 0.8~1.2 part of camphor, 3~8 parts of boric acid, glycerine 250~
300 parts, 90~100 parts of gelatin.
3. the Baicao Fuyanqing preparation according to claim 1 for being used to repair vagina environment, it is characterised in that by following
The raw material of parts by weight is made：64 parts of kuh-seng, 32 parts of the tuber of stemona, 32 parts of frutus cnidii, 32 parts of hairyvein agrimony, 32 parts of folium callicarpae pedunculatae, alum 1.0
Part, 0.5 part of borneol, 1 part of camphor, 6 parts of boric acid, 260 parts of glycerine, 95 parts of gelatin.
4. the Baicao Fuyanqing preparation for being used to repair vagina environment according to claim 1 or 2 or 3, it is characterised in that
The Baicao Fuyanqing preparation is vagina external preparation.
5. the Baicao Fuyanqing preparation for being used to repair vagina environment according to claim 1 or 2 or 3, it is characterised in that
The Baicao Fuyanqing preparation is suppository.
6. the preparation method for being used to repair the Baicao Fuyanqing preparation of vagina environment according to claim 1 or 2 or 3,
It is characterised in that it includes following steps：
（1）Kuh-seng, the tuber of stemona, frutus cnidii, hairyvein agrimony and folium callicarpae pedunculatae are weighed, is added water to cook three times, first and second time is each 2~3 hours,
1~2 hour for the third time, decocting liquid three times is merged and filtered to get filtrate, the filtrate is condensed into clear cream；Then to the clear cream
In plus 95% ethanol until alcohol content stands 24 hours, takes supernatant up to untill 60%, filtering；Finally by the supernatant after filtering
Recovery ethanol is simultaneously condensed into thick paste, standby；
（2）Glycerine is taken, is heated to 115 DEG C~120 DEG C, adds gelatin, is stirred continuously to gel solubilizing, formation glycerin gelatine base
Matter, alum, boric acid are then ground into fine powder, and added in glycerol gelatin matrix, be eventually adding after thick paste stirs and stop
Heating；
（3）Borneol is dissolved with a small amount of ethanol and camphor obtains mixed liquor, is added when glycerol gelatin matrix is cooled into 90 DEG C described mixed
Liquid is closed, and is stirred, last moulding finished product.
7. the preparation method according to claim 6 for being used to repair the Baicao Fuyanqing preparation of vagina environment, its feature
It is, step（1）In, at 25 DEG C, concentrate the filtrate to the clear cream that relative density is 1.08~1.10.
8. the preparation method according to claim 6 for being used to repair the Baicao Fuyanqing preparation of vagina environment, its feature
It is, step（1）In, at 25 DEG C, supernatant is reclaimed into ethanol and is concentrated into the thick paste that relative density is 1.30 ~ 1.35.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710695887.4A CN107362310A (en) | 2017-08-15 | 2017-08-15 | It is a kind of to be used to repair Baicao Fuyanqing preparation of vagina environment and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710695887.4A CN107362310A (en) | 2017-08-15 | 2017-08-15 | It is a kind of to be used to repair Baicao Fuyanqing preparation of vagina environment and preparation method thereof |
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| Publication Number | Publication Date |
|---|---|
| CN107362310A true CN107362310A (en) | 2017-11-21 |
Family
ID=60309630
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|---|---|---|---|
| CN201710695887.4A Pending CN107362310A (en) | 2017-08-15 | 2017-08-15 | It is a kind of to be used to repair Baicao Fuyanqing preparation of vagina environment and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113975358A (en) * | 2021-12-03 | 2022-01-28 | 贵州长生药业有限责任公司 | Baicao Fuyanqingshuan composition and its preparing method |
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|---|---|---|---|---|
| CN1500522A (en) * | 2002-11-15 | 2004-06-02 | 贵州长生制药有限责任公司 | Suppository for treating gynecopathy and its preparation technology |
| CN1981858A (en) * | 2005-12-16 | 2007-06-20 | 杨伟荣 | Baicao gel for treating gynecologic inflammation |
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2017
- 2017-08-15 CN CN201710695887.4A patent/CN107362310A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1500522A (en) * | 2002-11-15 | 2004-06-02 | 贵州长生制药有限责任公司 | Suppository for treating gynecopathy and its preparation technology |
| CN1981858A (en) * | 2005-12-16 | 2007-06-20 | 杨伟荣 | Baicao gel for treating gynecologic inflammation |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113975358A (en) * | 2021-12-03 | 2022-01-28 | 贵州长生药业有限责任公司 | Baicao Fuyanqingshuan composition and its preparing method |
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Application publication date: 20171121 |