CN107349382A - 一种治疗强直性脊柱炎的督灸粉及其制备方法 - Google Patents
一种治疗强直性脊柱炎的督灸粉及其制备方法 Download PDFInfo
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- CN107349382A CN107349382A CN201610298067.7A CN201610298067A CN107349382A CN 107349382 A CN107349382 A CN 107349382A CN 201610298067 A CN201610298067 A CN 201610298067A CN 107349382 A CN107349382 A CN 107349382A
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Abstract
一种治疗强直性脊柱炎的督灸粉及其制备方法,由以下按照重量配比中药原料及西药原料制备而成:中药原料:木瓜、海风藤、蕲蛇、夜交藤、姜黄、大血藤、伸筋草、臭梧桐、青风藤、土茯苓、秦艽、独活、茜草、虎杖、川芎、苏木、丹参、红花、桃仁、紫草、大青叶、黄药子、败酱草、金荞麦、蜈蚣、海马、千年健、全蝎、威灵仙、巴戟天、五加皮、桑寄生、鸡血藤、狗脊、鹿衔草、天麻、醋制延胡索、乳香、没药、麝香、冰片、洋金花;西药原料:维生素B1片、维生素B12片。本治疗药粉根据中医理论,辨证施治,标本兼制,能明显提高患者的治愈率。
Description
技术领域
本发明涉及一种以中草药为主要原料制备的药粉,具体地说是一种治疗强直性脊柱炎的督灸粉及其制备方法。
背景技术
强直性脊柱炎 (AS) 是一种病因未明,以中轴关节慢性炎症为主的全身性疾病。主要累及骶髂关节、髋关节、椎间关节、肋椎关节,以骶髂关节病变最为多见,约有1/3 患者周围关节出现炎症,并可累及眼部、心脏、肺脏、神经***以及泌尿***。其主要病理是改变关节和关节周围组织、韧带、椎间盘的钙化,最终发生脊柱强直。所以说强直性脊柱炎是致残率高、严重影响人们健康的疾病。强直性脊柱炎属于中医“痹症”或“腰病”的范畴,在西医属于风湿病范畴。本病的发病部位主要是腰骶部和脊背部,与肾和督脉关系最为密切。肾为先天之本,主骨生髓,肾系盈脊,督脉狭脊盈腰中,总督一身之阳,与肾关系尤为密切,故本病的发生多与肾气虚督脉空虚有关。在正气亏虚的情况下,风寒涩热之初乘虚而入,痹阻督脉,气血运行不畅,不通则病而致腰背部疼痛。本病多发生于青少年男性,40 岁以后患病者少见。由于本病的病因、发病的机理尚不明确,所以缺乏特异性治疗方法。
目前,主要有体疗、理疗、药物和外科治疗等。1.体疗:体育疗法对各种慢性疾病均有好处,对AS更为重要。可保持脊柱的生理弯曲,防止畸形;维持正常的呼吸功能,保持骨密度和强度,防止骨质疏松和肢体废用性肌肉萎缩等,具体可作以下运动。(1)深呼吸 :每天早晨、工作休息时间及睡前均应常规作深呼吸运动,深呼吸可以维持胸廓最大的活动度,保持良好呼吸功能;(2)颈椎运动:头颈部可作向前、向后、向左、向右转动,以及头部旋转运动,以保持颈椎的正常活动度;(3)腰椎运动:每天作腰部运动、前屈、后仰、侧弯和左右旋转躯体,使腰部脊柱保持正常的活动度;(4)肢体运动;可作俯卧撑、斜撑,下肢前屈后伸、扩胸运动及游泳等, 游泳既有利于四肢运动,又有助于增加肺功能和使脊柱保持生理曲度,是AS 最适合的全身运动。2. 物理治疗 :理疗一般可用热疗,如热水浴、水盆浴或淋浴,矿泉温泉浴等,以增加局部血液循环,使肌肉放松,减轻疼痛,有利于关节活动,保持正常功能,防止畸形。3.药物治疗:治疗AS的药物可分为三类:①控制病情活动,影响病程进展的药物,如柳氮磺胺吡啶,甲氨蝶呤,现在最新的还有疗效显著的“生物制剂”益赛谱 - 肿瘤坏死因子抗体融合蛋白,适用于病情活动的AS,伴外周关节炎的AS和新近发现的AS;②非甾体抗炎药,适用于夜间严重疼痛及僵硬病人,可在睡前服用;③镇痛药与肌松药如镇痛新、强痛啶肌舒平,常用于长期应用非甾体类抗炎药无效者。4.手术治疗:严重脊柱驼背畸形待病情稳定后可作矫正手术;腰椎畸形者可行脊椎截骨术矫正驼背;颈 7 胸1截骨术可矫正颈椎严重畸形;髋关节严重屈曲畸形,可行全髋关节转换术或髋关节成形术,但效果不够理想,术后易再强直。现有技术的体疗、理疗法,存在疗程长、效果差的问题;而药物疗法,大多为口服西药,存在治疗成本高和有副作用的问题:而手术治疗存在患者痛苦大的问题。
督灸又称长蛇灸,是一种在督脉上施以隔药或隔姜或隔蒜灸的疗法。督灸是在人体的脊柱上(中医所说的督脉的脊柱段上)施以隔物艾灸的一种特色中医外治法,是在中医古老的疗法“铺灸”的基础上经过改良而来的,适用于缓解因风寒、邪湿所致的颈、肩、腰、腿等关节疼痛及软组织扭挫伤等所致的疼痛,尤擅治疗由强直性脊柱炎所引起的疼痛。其治疗方法:令患者裸背俯卧于床上,取督脉大椎至腰俞的脊柱部位。常规消毒后在治疗部位涂抹生姜汁,再在治疗部位上撒上督灸粉,之后在其上覆盖桑皮纸,然后再在桑皮纸上铺生姜泥如梯状,最后在姜泥上面放置艾柱,然后点燃,连续灸治后把姜泥和艾灰去除,然后用湿热毛巾把治疗部位擦干净。本发明强直性脊柱炎督灸粉针对强直性脊柱炎患者的临床症状通过激发协调诸经,发挥平衡阴阳、抵御病邪、温补督脉,强化真元,温通气血,调整虚实的功效;多种药物联合应用起到止痛、生肌消肿、活血化瘀、通络的作用,且能标本兼治、无副作用、价格低廉。
发明内容
本发明的目的是提供一种以中草药为主要原料制备的药粉,具体地说是一种治疗强直性脊柱炎的督灸粉及其制备方法。
为实现上述目的,本发明采用的技术方案为:
一种治疗强直性脊柱炎的督灸粉,其特征是,由以下重量配比的中药原料及西药原料组成:
中药原料:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、乳香50g、没药50g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、麝香1g、冰片1.5g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g、洋金花3g;
西药原料:维生素B1片(10mg/片)10片;维生素B12片(25ug/片)40片;
将上述原料药按以下步骤制备:
(1)将上述中药原料中:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g干燥后混合粉碎成细粉,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(2)将乳香50g、没药50g、麝香1g、冰片1.5g、洋金花3g分别单独粉碎成细粉,混合均匀,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(3)用时取维生素B1片(10mg/片)1片,维生素B12片(25ug/片)4片粉碎成细粉与步骤(1)、(2)中的备用药粉各一份混合均匀,为最终督灸粉。
一种制备强直性脊柱炎督灸粉的方法,其特征是:将所述原料药按以下步骤制备:
(1)将上述中药原料中:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g干燥后混合粉碎成细粉,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(2)将乳香50g、没药50g、麝香1g、冰片1.5g、洋金花3g分别单独粉碎成细粉,混合均匀,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(3)用时取维生素B1片(10mg/片)1片,维生素B12片(25ug/片)4片粉碎成细粉与步骤(1)、(2)中的备用药粉各一份混合均匀,为最终督灸粉。
本发明的有益效果:
1.众药综治、标本兼治。本发明强直性脊柱炎督灸粉针对强直性脊柱炎患者的临床症状通过激发协调诸经,发挥平衡阴阳、抵御病邪、温补督脉,强化真元,温通气血,调整虚实的功效;多种药物联合应用起到止痛、生肌消肿、活血化瘀、通络的作用,且能标本兼治、无副作用、价格低廉。
2.中药配合西药应用,能维持神经组织、肌肉活动的代谢与功能正常,促进红细胞的发育和成熟,使肌体造血机能处于正常状态,预防恶性贫血;维护神经***健康,使治疗的效果倍增。
具体实施方式
下面结合具体实施例对本发明作进一步说明:
本发明药粉根据中医理论,辨证施治,采用多种药物联合应用,针对强直性脊柱炎患者的临床症状通过激发协调诸经,发挥平衡阴阳、抵御病邪、温补督脉,强化真元,温通气血,调整虚实的功效;多种药物联合应用起到止痛、生肌消肿、活血化瘀、通络的作用,且能标本兼治、无副作用、价格低廉。
实施例
本发明的中药原料组成:
一种治疗强直性脊柱炎的督灸粉,其特征是,由以下重量配比的中药原料及西药原料组成:
中药原料:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、乳香50g、没药50g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、麝香1g、冰片1.5g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g、洋金花3g;
西药原料:维生素B1片(10mg/片)10片;维生素B12片(25ug/片)40片;
将上述原料药按以下步骤制备:
(1)将上述中药原料中:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g干燥后混合粉碎成细粉,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(2)将乳香50g、没药50g、麝香1g、冰片1.5g、洋金花3g分别单独粉碎成细粉,混合采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(3)用时取维生素B1片(10mg/片)1片,维生素B12片(25ug/片)4片粉碎成细粉与步骤(1)、(2)中的备用药粉各一份混合均匀,为最终督灸粉。
本发明的使用方法:令确诊为强直性脊柱炎疼痛分级为II 级:X 线检查 : 骶髂关节锯齿样改变,部分韧带钙化,小关节骨质破坏。血沉25~58mm/h的患者裸背俯卧于床上,取督脉大椎至腰俞的脊柱部位。以75%的酒精消毒后在治疗部位涂抹生姜汁,再在治疗部位上撒上督灸粉,之后在其上覆盖桑皮纸,然后再在桑皮纸上铺生姜泥如梯状,最后在姜泥上面放置艾柱,然后点燃,连续灸治后把姜泥和艾灰去除,然后用湿热毛巾把治疗部位擦干净,每5天治疗一次,10次为一疗程。
本发明药理分析
本发明原料中:1.木瓜、海风藤、蕲蛇、夜交藤、姜黄、大血藤—活血祛瘀,消肿止痛,祛风通络;2.乳香、没药—活血止痛,消肿生肌;3.伸筋草、臭梧桐、青风藤—舒筋活络;4.土茯苓、秦艽、独活—解毒,利湿,通利关节; 5.茜草、虎杖、川芎、苏木、丹参、桃仁、红花、醋制延胡索—活血祛瘀,消肿止痛;6.麝香、冰片-活血散结、消肿止痛;7.紫草、大青叶、败酱草、黄药子、金荞麦—解毒消肿,活血化瘀;8.天麻、全蝎、蜈蚣—强筋骨,活血散结,消肿止痛;9.巴戟天、千年健、五加皮、桑寄生、鸡血藤、狗脊、鹿衔草、海马—祛风湿,补肝肾,强筋骨;10.洋金花、威灵仙—解痉止痛;11.维生素B1、维生素B12片—维持神经组织、肌肉活动的代谢与功能正常。
1.活血祛瘀,消肿止痛,祛风通络:原料中的木瓜、海风藤、蕲蛇、夜交藤、姜黄、大血藤中的活性因子能迅速起到活血祛瘀,消肿止痛,祛风通络的作用。现代药理研究表明:木瓜含有多种化学成分,主要有去甲五环三萜皂苷类化合物、木脂素苷类化合物、黄酮类和酚性等成分,具有镇痛、抗炎的药理活性;海风藤中含有的酮、醇、生物碱类、挥发油类等有效成分,具有抗炎、止痛、抗氧化的作用;蕲蛇中的氨基酸和蛋白质等有效成分还具有很好的镇痛、镇静抗血栓形成,促进血液流动的作用,能促进病变部位迅速恢复正常功能;夜交藤主含大黄素,大黄素甲醚,还含夜交藤乙酰本甙具有镇静、疏通经络、止痒的作用;姜黄所含的姜黄素和挥发油具有抗炎、抗真菌及抗氧化的作用;大血藤的主要化学成分有酚酸类、蒽醌类、黄酮类、总皂苷、鞣质类等,其药理作用还有抗菌、抗病毒、消炎、抗肿瘤等作用。
2.活血止痛,消肿生肌:原料中的乳香、没药中的活性因子能迅速起到活血止痛,消肿生肌的作用。现代药理研究表明:这两种药物还含有多种抗菌素,其中所含的树脂、树胶、挥发油具有较强的镇痛作用,能对患者起到很好的镇痛作用。
3.舒筋活络:原料中的伸筋草、臭梧桐、青风藤均有很好的舒筋活络的作用。现代药理研究表明:伸筋草含石松碱,棒石松宁碱等生物碱,石松三醇,石松四醇酮等萜类化合物,β-谷甾醇等甾醇,及香草酸,阿魏酸等,伸筋草醇提取物有明显镇痛作用;臭梧桐含有苯乙醇苷、黄铜、生物碱等,具有抗炎、抗氧化、镇静的作用;青风藤主含生物碱、甾醇、具有祛风镇痛、消炎的作用。
4.解毒,利湿,通利关节:原料中的土茯苓、秦艽、独活具有很好的解毒,利湿,通利关节的作用。现代药理研究表明:土茯苓所含茯苓多糖、蛋白质、卵磷脂等多种物质具有抗癌,消肿散结的作用,所含的落新妇甙具有明显的镇痛作用。秦艽所含的秦艽碱甲具有抗炎的作用。独活所含的有效成分具有镇静、催眠、镇痛的作用,所含的欧芹酚甲醚和花椒毒素具有抗炎作用,所含的香柑内酯、花椒毒素等有光敏及抗肿瘤作用。
5.活血祛瘀,消肿止痛:原料中的茜草、虎杖、川芎、苏木、丹参、桃仁、红花、醋制延胡索具有活血祛瘀,消肿止痛的作用。现代药理研究表明:茜草、虎杖、川芎、苏木、丹参、桃仁、红花、醋制延胡索中所含的三萜类、皂苷、氨基酸、黄酮、糖和多种无机元素,具有抗疲劳、抗缺氧、免疫调节、疗疮痈等作用。
6.活血散结、消肿止痛:原料中的麝香、冰片均有活血散结、消肿止痛的作用。现代药理研究表明:麝香中所含的桂皮醛,酮类,烯类成分、生物碱类、挥发油类具有很强的镇痛,抗炎等作用。冰片还具有消炎、镇痛、双向调节神经***,提高其他药物生物利用度的作用。
7.解毒消肿,活血化瘀:原料中的紫草、大青叶、败酱草、黄药子、金荞麦具有很强的解毒消肿,活血化瘀的作用。现代药理研究表明:紫草、大青叶、败酱草、黄药子、金荞麦中所含的生物碱,非生物碱及20多种具有镇静、解痉、免疫调节、抗放射、抗肿瘤的有效成分,从而改善急性强直性脊柱炎引起的背部组织的水肿、疼痛。
8.强筋骨,活血散结,消肿止痛:原料中的天麻、全蝎、蜈蚣能有效强筋骨,活血散结,消肿止痛。现代药理研究表明:天麻中所含的水溶性多糖、甲醇、糖苷有镇静、催眠、增智、补脑、健脑、明目、消炎、增强免疫的功效,对老年人延缓衰老,延长寿命,对中年人消除疲劳,保持充沛的体力,对青少年增强记忆,改善视力十分有益;全蝎中的蝎毒具有消肿止痉、镇痛的作用;蜈蚣中的脂肪油、胆甾醇、蚁酸挥发油具有抗肿瘤、抗菌、促进免疫功能的作用。
9.祛风湿,补肝肾,强筋骨:原料中的巴戟天、千年健、五加皮、桑寄生、鸡血藤、狗脊、鹿衔草、海马含有的多种生物碱,挥发油具有很强的祛风湿,补肝肾,强筋骨的作用,现代药理研究表明:巴戟天、千年健、五加皮、桑寄生、鸡血藤、狗脊、鹿衔草、海马中含有的甾体皂苷、黄酮苷、氨基酸等具有抗肿瘤、止血、镇痛、调节免疫的作用。
10.解痉止痛:原料中的洋金花、威灵仙的有效成分具有解痉止痛的作用,现代药理研究表明:洋金花中的生物碱对病变部位具有麻醉,解痉,镇痛的作用,威灵仙为治疗痹痛拘挛麻木之要药,所含的原白头翁素、糖皂甙等成分还具有抗菌消炎的作用,可防止受伤部位由于水肿,而导致的炎性浸润。
11.维护神经髓鞘的代谢与功能:原料中的维生素B1、维生素B12能够维护神经髓鞘的代谢与功能,促进受损神经根的修复,并能维持神经组织、肌肉活动的代谢与功能正常,促进红细胞的发育和成熟,使肌体造血机能处于正常状态,预防恶性贫血,维护神经***健康。
本发明药效学统计:
1.一般临床资料:选取同期入住我院,确诊为强直性脊柱炎疼痛分级为II 级:X 线检查 : 骶髂关节锯齿样改变,部分韧带钙化,小关节骨质破坏。血沉25~58mm/h的患者218例,随机分为两组;治疗组109例,男73例,女36例;年龄18.48~39.42岁,平均26.32岁;对照组109例,男68例,女40例,年龄17.72~41.34岁,平均27.82岁;这两个随机组患者在性别、年龄、营养状况等方面比较,差异无统计学意义(P>0.05)。
2.治疗方法:对照组患者给予常规治疗:吲哚美辛、 布洛芬和炎痛喜康等药物睡前服用50天为一疗程;治疗组患者在常规治疗的基础上加用督灸治疗,每5天治疗一次,10次为一疗程。
3.评价指标:参照《中药新药临床研究指导原则》中的疗效标准:①临床痊愈:中医临床症状、体征消失或基本消失,证候积分减少≥95%;②显效:中医临床症状、体征消失或基本消失,证候积分减少≥70%;③有效:中医临床症状、体征消失或基本消失,证候积分减少≥30%;④无效:中医临床症状、体征均无明显改善或加重,证候积分减少﹤30%。
4.统计学方法:应用SPSS13.0统计分析软件进行数据分析,两组间疗效比较采用x²检验,计量资料采用t检验,p﹤0.05为差异有统计学意义。
表1:经过一个疗程后两组患者治疗效果比较[例(%)]
注:与对照组比较χ²=11.74 p<0.05有显著差异
表2:经过两个疗程后两组患者治疗效果比较[例(%)]
注:与对照组比较χ²=15.82 p<0.05有显著差异
5.结论:经过两个疗程后两组患者治疗效果比较,由表1、表2可知治疗组的治愈率明显高于对照组,差异有统计学意义(P<0.05)。同时本发明药粉外涂避免了口服应用西药的对人体的损害和局部封闭对患者造成的损伤及恐惧心理。
Claims (2)
1. 一种治疗强直性脊柱炎的督灸粉,其特征是,由以下重量配比的中药原料及西药原料组成:
中药原料:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、乳香50g、没药50g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、麝香1g、冰片1.5g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g、洋金花3g;
西药原料:维生素B1片(10mg/片)10片;维生素B12片(25ug/片)40片;
将上述原料药按以下步骤制备:
(1)将上述中药原料中:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g干燥后混合粉碎成细粉,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(2)将乳香50g、没药50g、麝香1g、冰片1.5g、洋金花3g分别单独粉碎成细粉,混合均匀,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(3)用时取维生素B1片(10mg/片)1片,维生素B12片(25ug/片)4片粉碎成细粉与步骤(1)、(2)中的备用药粉各一份混合均匀,为最终督灸粉。
2. 一种制备强直性脊柱炎督灸粉的方法,其特征是:将所述原料药按以下步骤制备:
(1)将上述中药原料中:木瓜100g、海风藤150g、蕲蛇100g、夜交藤100g、姜黄100g、大血藤120g、伸筋草100g、臭梧桐100g、青风藤100g、土茯苓100g、秦艽100g、独活100g、茜草50g、虎杖150g、川芎100g、苏木50g、丹参150g、红花100g、桃仁100g、紫草100g、大青叶100g、黄药子50g、败酱草100g、金荞麦100g、蜈蚣50g、海马30g、千年健50g、全蝎50g、威灵仙50g、巴戟天50g、五加皮150g、桑寄生100g、鸡血藤150g、狗脊150g、鹿衔草100g、天麻50g、醋制延胡索50g干燥后混合粉碎成细粉,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(2)将乳香50g、没药50g、麝香1g、冰片1.5g、洋金花3g分别单独粉碎成细粉,混合均匀,采用环氧乙烷灭菌后分成10份,塑封于塑料袋内备用;
(3)用时取维生素B1片(10mg/片)1片,维生素B12片(25ug/片)4片粉碎成细粉与步骤(1)、(2)中的备用药粉各一份混合均匀,为最终督灸粉。
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