CN107335114A - Needle head structure - Google Patents
Needle head structure Download PDFInfo
- Publication number
- CN107335114A CN107335114A CN201611019932.6A CN201611019932A CN107335114A CN 107335114 A CN107335114 A CN 107335114A CN 201611019932 A CN201611019932 A CN 201611019932A CN 107335114 A CN107335114 A CN 107335114A
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- Prior art keywords
- chamber
- needle
- housing
- needle body
- head structure
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3286—Needle tip design, e.g. for improved penetration
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a kind of needle head structure, and it includes needle body, housing and separator.The needle body chamber connection pin mouth of needle body.Housing connects needle body and comprising housing cavity and perforate, needle body chamber housing cavity and form syringe needle cavity.Syringe needle cavity is separated out first chamber and second chamber by separator, and first chamber is isolated from each other with second chamber.Pin mouth is separated out injection port and blood back mouth by separator, and first chamber connects blood back mouth and perforate equipped with filler and connection injection port, second chamber.Because no matter the blood vessel arterial-venous of human body in itself is with the presence of natural pressure, the phenomenon of blood back is had in injected into blood vessel, confirm blood back situation with perforate whereby using the transparency of second chamber, injector can be made to avoid getting to blood vessel and causing blood vessel embolism in injection, and then improve operation safety.
Description
Technical field
The present invention is on a kind of needle head structure, can confirm blood back situation immediately especially with regard to one kind and improve operation peace
The needle head structure of full property.
Background technology
Thing is being filled using the prong (sharp needle) of general needle set (such as：Sodium hyaluronate) injection when, to avoid
Bacterium infection, the air in syringe needle cavity will not be expelled to inside tissue.Before the injection, what user can first be exhausted is dynamic
Make, filler be first pushed into the cavity in syringe needle, after the cavity of needle wall is filled with sodium hyaluronate, determine in syringe needle
Without air, can just be injected.
The filler for being generally used for curing U.S. injection is not liquid, is the material close to solid, so in injection, must
The position of blood vessel need be avoided.Once because injected into blood vessel, it will cause the blocking of blood vessel, easily cause cutaneous necrosis, lose
The serious side effect such as bright, apoplexy, pulmonary embolism.
The position of filler injection is typically subcutaneous, but in actual injection, method is not definitely visual in fact
Hypodermis whether there is blood vessel presence, so all injections (blind injection) of blindness at last, its be because when injecting not
There is the position that method absolutely determines injection.Therefore, in practice, injector must know anatomic construction, and it is appropriate to select
Injection planes and position, or using blunt needle (blunt cannula), also or in injection carry out pumpback (aspirate)
Action, confirmation whether there is blood back so that ensure will not be in injected into blood vessel.
Currently known technology is that the action of pumpback is carried out in injection, to confirm whetheing there is blood back.However, typically inject
Filler has different coefficient of viscosities according to the material of itself, and compares the filler of stickiness, such as：Crystallite porcelain
(Radiesse), Yi-School lotuses silk (Ellanse) or the sodium hyaluronate of macromolecular, the cavity that can be filled up in syringe needle after exhaust.If
When injecting these fillers, needle point in the blood vessels, even if we carry out the action of pumpback, as the shadow of filler stickiness
Ring, cause to stick and blood can not be back in syringe very much, therefore blood back phenomenon can not be observed.If at this time also continue to push pin
Filler injected into blood vessel will result in the embolism of blood vessel by cylinder.So the method for pumpback is just used at last, if using glutinous
The big filler of stagnant coefficient, still there is the risk of erroneous judgement.
Another known technology is to use blunt needle, and its syringe needle is not sharp, but arc-shaped is presented.Compare in theory
It will not hurt blood vessel, but too thin blunt needle, or the puncture force with the prong (sharp needle) of degree such as certain, therefore
The risk for still suffering from thorn to blood vessel using blunt needle is present.From the foregoing, either prong or blunt needle, can in injection
Certain danger is produced, it is primarily due to after needle point enters skin, and injector has no idea to know needle point really
Whether in the blood vessels.Therefore, shortage can quickly confirm blood back and the pin of operative failure risk can be greatly reduced in the market
Header structure, therefore related dealer is seeking its solution.
The content of the invention
Therefore, the present invention provides a kind of needle head structure, and it can allow injector after needle point enters skin, without through
Pumpback is crossed, utilizes intravascular naturally blood back phenomenon caused by pressure, you can learn needle point whether in the blood vessels.In addition, this hair
Bright needle head structure has disconnected first chamber and second chamber, and first chamber is equipped with filler, and second chamber is transparent
And there is perforate, to confirm the situation of blood back.Blood back situation can be confirmed when perforate is opened, if injection can be avoided to fill out when closing
Fill thing and flow back into second chamber, injector can be made to avoid filler from squeezing into blood vessel in injection and cause blood vessel embolism, and then
Improve the security of operation.In addition, special needle head structure enables injector easily to operate, allow injector more can be successfully complete
Into the injection course for the treatment of.
One embodiment of the present invention is a kind of needle head structure, to injection fillers thing and monitors blood back situation.This syringe needle
Structure includes needle body, housing and separator.Needle body includes needle body chamber and pin mouth, needle body chamber connection pin mouth.Furthermore housing
Connect needle body.Housing includes housing cavity and perforate, needle body chamber housing cavity and form syringe needle cavity.In addition, separate
Part is located in syringe needle cavity, and syringe needle cavity is separated out first chamber and second chamber by this separator.First chamber and second
Chamber is isolated from each other, and pin mouth is separated out injection port and blood back mouth by separator.First chamber is equipped with filler and connects injection port,
And second chamber then connects blood back mouth and perforate.
Whereby, needle head structure of the invention can allow injector after needle point enters skin, during injection
Need not move through pumpback and can determine that the position of needle point is in the blood vessels or outside blood vessel.Furthermore special chamber structure can use
To confirm the situation of blood back, injector is set to avoid filler from squeezing into blood vessel in injection and cause blood vessel embolism, and then improve
The security of operation.
The other embodiments of aforementioned embodiments are as follows：Foregoing needle body can be blunt needle or prong.In addition, foregoing housing is set
There is switch portion, this switch portion can be opened and closed perforate.
Another embodiment of the present invention is a kind of needle head structure, to injection fillers thing and monitors blood back situation.This pin
Header structure includes interior pin portion and outer pin portion.Wherein interior pin portion includes the first needle body and the first housing.First needle body includes needle body chamber
Room and pin mouth, needle body chamber connection pin mouth.And the first housing then connects the first needle body, and the first housing includes housing cavity.Shell
Fluid chamber connects needle body chamber and forms first chamber.This first chamber is equipped with filler and connection pin mouth.In addition, outer pin portion ring
Located at the outside in interior pin portion, and outer pin portion includes perforate and blood back mouth.Form second chamber between outer pin portion and interior pin portion, second
Chamber is isolated from each other with first chamber.
Whereby, needle head structure of the invention forms particularly ring-shaped chamber by internal and external pin portion, and it can be used to confirm blood back
Situation, and injector can be allowed to avoid filler from squeezing into blood vessel in injection and cause blood vessel embolism, operation is significantly increased
Security.
The other embodiments of aforementioned embodiments are as follows：Foregoing outer pin portion can include the second needle body and the second housing.Wherein
Second needle body is located on the outside of the first needle body.Blood back mouth is opened on the second needle body.In addition, the second housing connects the second needle body
And it is located on the outside of the first housing.Perforate is opened on the second housing.Foregoing second needle body is blunt needle or prong.It is in addition, preceding
Switch portion, switch portion opening and closing perforate can be provided with by stating the second housing.Second chamber connects blood back mouth and perforate.Foregoing second housing can
Include close end and distal portion.Close end has two ends, and wherein one end connects the second needle body, and the other end then connects distal portion.Open
Hole is in distal portion.Wherein interior pin portion is displaceably positioned at close end and distal portion.In addition, foregoing outer pin portion can the company of including
Joint chair and injecting assembly.Connecting seat connects perforate and the second housing of connection.Injecting assembly connects connecting seat, and injecting assembly includes
Injection housing and injection rod.The detachably connected connecting seat of injection housing.Injection rod is then located at injection housing and displaceably fixed
In injection housing.Foregoing filler can be sodium hyaluronate (Hyaluronic Acid), calcium hydroxy apetite (Calcium
Hydroxyapatite, Radiesse), polycaprolactone (Polycaprolactone, Ellanse), collagen
(Collagen), PLLA (Poly-L-Lactic Acid, PLLA, Sculptra), fatty (Fat), polypropylene amine
(Polyacrylamide, Aaquamid), Triamcinolone Acetonide (Triamcinolone Acetonide) or lidocaine
(Lidocaine)。
Another embodiment of the invention is a kind of needle head structure, to injection fillers thing and monitors blood back situation.This pin
Header structure includes needle body, housing and conduit.Needle body includes needle body chamber, pin mouth and separator.Pin mouth connects needle body chamber.
Separator is then located in needle body chamber.Housing connects needle body, and housing includes housing cavity and perforate, needle body chamber housing
Chamber.Conduit has injection port and tube wall, and conduit is displaceably arranged in housing cavity and needle body chamber and filler is housed.This
Outside, separator is separated by the first spacing with pin mouth, and injection port is separated by the second spacing with pin mouth.The second spacing is smaller than when first
When, separator separates with tube wall and forms blood back mouth；When the first spacing is more than or equal to the second spacing, tube wall connection separator,
So as to making blood back mouth close.
Whereby, needle head structure of the invention wears needle body to realize the injection of filler and blood back really by conduit
Recognize.When injector utilizes conduit injection, filler can be avoided to squeeze into blood vessel and cause blood vessel embolism, the safety of operation can be improved
Property.Furthermore special needle head structure combination conduit enables injector easily to operate, and then injector can more favorably accomplish
The injection course for the treatment of.
Brief description of the drawings
Fig. 1 is the schematic perspective view for the needle head structure for illustrating one embodiment of the invention.
Fig. 2 is the side view for the needle head structure for illustrating Fig. 1.
Fig. 3 is the sectional view for the hatching line 3-3 for illustrating Fig. 2.
Fig. 4 A are the closing schematic diagrames for the switch portion for illustrating Fig. 1.
Fig. 4 B are the unlatching schematic diagrames for the switch portion for illustrating Fig. 1.
Fig. 5 is the operation chart for the needle head structure for illustrating Fig. 1.
Fig. 6 is the side view for the needle head structure for illustrating another embodiment of the present invention.
Fig. 7 is the sectional view for the hatching line 7-7 for illustrating Fig. 6.
Fig. 8 is the schematic perspective view for the needle head structure for illustrating further embodiment of this invention.
Fig. 9 is the side view for the needle head structure for illustrating yet another embodiment of the invention.
Figure 10 A are the side views for illustrating the needle head structure of another embodiment of the present invention when confirming blood back.
Figure 10 B are the side views for illustrating Figure 10 A needle head structure in injection.
Figure 11 A are the side views for illustrating the needle head structure of further embodiment of this invention when confirming blood back.
Figure 11 B are the side views for illustrating Figure 11 A needle head structure in injection.
Figure 12 A are the schematic diagrames for the needle head structure insertion blood vessel for illustrating yet another embodiment of the invention.
Figure 12 B are the schematic diagrames for illustrating Figure 12 A needle head structure in injection.
Figure 13 A are the sectional views in the outer pin portion for the needle head structure for illustrating another embodiment of the present invention.
Figure 13 B are the side views for illustrating Figure 13 A needle head structure in injection.
Figure 13 C are the side views for the needle head structure for illustrating further embodiment of this invention.
Embodiment
It the following drawings illustrate multiple embodiments of the present invention.As clearly stated, the details in many practices
It will be explained in the following description.It should be appreciated, however, that the details in these practices is not applied to limit the present invention.Also
It is to say, in section Example of the present invention, the details in these practices is non-essential.In addition, for the sake of simplifying accompanying drawing, some
Known usual structure will be illustrated in a manner of simply illustrating in the accompanying drawings with element；And the element repeated will likely use phase
Same numbering represents.
Also referring to Fig. 1~4B.Fig. 1 is the schematic perspective view for the needle head structure 100 for illustrating one embodiment of the invention.Figure
2 be the side view for the needle head structure 100 for illustrating Fig. 1.Fig. 3 is the sectional view for the hatching line 3-3 for illustrating Fig. 2.Fig. 4 A illustrate Fig. 1
The closing schematic diagram of switch portion 330.Fig. 4 B are the unlatching schematic diagrames for the switch portion 330 for illustrating Fig. 1.As illustrated, needle head structure
100 be to injection fillers thing, and filler can be sodium hyaluronate (Hyaluronic Acid), crystallite porcelain (Radiesse), Yi-School lotus silks
(Ellanse), collagen (Collagen), PLLA (Poly-L-Lactic Acid；PLLA；Sculptra), fat
Fat (Fat), polypropylene amine (Polyacrylamide；Aaquamid) or the medicine in other unsuitable injected into blood vessel, such as：
Triamcinolone Acetonide (Triamcinolone Acetonide) or lidocaine (Lidocaine).Above-mentioned crystallite porcelain
(Radiesse) Main Ingredients and Appearance is calcium hydroxy apetite (Calcium Hydroxyapatite), and Yi-School lotuses silk (Ellanse)
Main Ingredients and Appearance be polycaprolactone (Polycaprolactone).From the foregoing, the needle head structure 100 of the present invention can be applied
In in a variety of medical demands.This needle head structure 100 includes needle body 200, housing 300 and separator 400.
Needle body 200 includes needle body chamber 210 and pin mouth 220, and needle body chamber 210 connects pin mouth 220.Needle body 200 can be blunt
Pin or prong.The front end of blunt needle is circular arc, and its pin mouth 220 is located at the side of front end.Prong is then in general angle pin.And
Needle body 200 is elongated metal tube, and is in hollow cylindrical, and skin is pierced into or extracts out to facilitate.
Housing 300 connects needle body 200.Housing 300 includes housing cavity 310, perforate 320, switch portion 330 and housing wall
340, needle body chamber 210 connects housing cavity 310 and forms syringe needle cavity 102.Furthermore perforate 320 is opened in housing wall 340
Side.The corresponding perforate 320 of switch portion 330 is simultaneously installed on housing wall 340, and switch portion 330 can open or close perforate 320.
In detail, switch portion 330 is a switchable movable valve, its housing cavity 310 that can be allowed inside housing 300 with it is extraneous
Air communicate or completely cut off.This switch portion 330 can be manually mode carry out controlling switch.In addition, housing 300 is moulded by hard
Made by glue, it can be transparent or translucent, and the housing wall 340 of the present embodiment is transparence, and it can allow injector quick
Whether ground is differentiated has blood to enter among housing cavity 310.
Separator 400 is located in syringe needle cavity 102, and syringe needle cavity 102 is separated out first chamber by this separator 400
410 with second chamber 420.First chamber 410 is isolated from each other with second chamber 420.In addition, separator 400 separates pin mouth 220
Go out injection port 430 and blood back mouth 440.First chamber 410 is equipped with filler and connection injection port 430, and second chamber 420 then connects
Take back blood mouth 440 and perforate 320.In other words, the present invention is that the syringe needle cavity 102 in needle head structure 100 is utilized into separator
400 are divided into the construction of two-chamber, and the two chambers are respectively first chamber 410 and second chamber 420.First chamber 410 and
Two chambers 420 can be waited greatly, or small one and large one.The shape of first chamber 410 and second chamber 420 can be it is circular,
Ellipse, rectangle or polygon.
Fig. 5 is the operation chart for the needle head structure 100 for illustrating Fig. 1, and the first chamber 410 of this needle head structure 100 is equipped with
Filler, second chamber 420 is then confirming blood back.The operation of needle head structure 100 can be divided into two steps.First step be
Piercing step, this piercing step are that needle body 200 is pierced into the skin for being applied hitter by injector (doctor or healthcare givers).Second
Individual step is injecting step, and it is that filler is injected in the tissue of non-vascular.
In piercing step, injector can confirm blood back situation using second chamber 420, and its principle mainly utilizes hair
The pressure that thin phenomenon and arteriovenous have in itself.If the thorn of pin mouth 220 arrives blood vessel, endovascular blood can be from second chamber
420 flow to perforate 320, and because the part of 340 adjacent openings of housing wall 320 is transparent material, therefore injector can directly observe and whether there is
The phenomenon of blood back occurs.Above-mentioned way is like that bleeder is in order to confirm whether needle point comes into typically when blood drawing
It is intravascular, the situation of blood back can be observed at the position of hard plastic housing 300 of syringe needle, because the blood of blood vessel has necessarily
Pressure, the air in needle point can be pushed away, and then make blood go to syringe needle connect housing 300 in.And the present invention
Second chamber 420 is exactly to have such function, there is air inside second chamber 420, but not with first chamber 410
Injection mass interconnect, so first chamber 410 and second chamber 420 are independent space.In injection, the second chamber
Room 420 keeps atmospheric pressure, once but needle point thorn to inside blood vessel because capillarity is with arteriovenous pressure, injector
Horse back can observes the phenomenon of blood back at the position of clear hard plastic casing 300 of syringe needle.And the present invention is compared to known
Syringe needle, in the blood vessels whether needle head structure 100 of the invention need not pass through the action of pumpback, it is possible to reach and know syringe needle
Effect, and injector is in piercing step, as long as seeing no blood back, it is possible to know needle point not in the blood vessels.Therefore, exist
Under operation condition without pumpback, injector not only adds operation using the injection that can feel at ease of needle head structure 100 of the present invention
Security, can also avoid many unnecessary medical tangles.In addition it is noted that before puncture, injector will first beat
The switch portion 330 of housing 300 is opened, because the air that switch portion 330 can allow in second chamber 420 keeps atmospheric pressure,
Once needle point is in the blood vessels, injector can see blood back at once and stop injecting.When injector determines the position to be injected simultaneously
It is determined that after no longer moving, you can close the valve of switch portion 330, subsequently into injecting step.
Because injecting step is that filler is injected in the tissue of non-vascular, if determining not having back after piercing step
Blood, injector is after knowing needle point not in the blood vessels, you can the filler that cylinder of pushing pin allows in first chamber 410 smoothly enters group
In knitting.In addition, in injecting step, switch portion 330, which closes valve, can be such that air stays in second chamber 420, and keep the
The fixed gas pressure of two chambers 420, and then allow the relation of filler not reason pressure of first chamber 410 to be back to the second chamber
In room 420, the space in second chamber 420 is caused still to keep unimpeded without being blocked.In addition, filler generally requires multiple spot
Injection, and injector can reuse this needle head structure 100 and carry out next position after needle head structure 100 is extracted
Treatment, as long as at this moment the valve of switch portion 330 is opened again, second chamber 420 can be recovered to detect the function of blood back once again.Borrow
This, needle head structure 100 of the invention can allow injector after needle point enters skin, and pin can be learnt by needing not move through pumpback
In the blood vessels whether, therefore injector is avoided that filler squeezes into blood vessel and causes blood vessel embolism in injection to point, and then improves
The security of operation.
Also referring to Fig. 6 and Fig. 7, Fig. 6 is the side view for the needle head structure 100a for illustrating another embodiment of the present invention.Figure
7 be the sectional view for the hatching line 7-7 for illustrating Fig. 6.As illustrated, needle head structure 100a is to injection fillers thing, this needle head structure
100a includes interior pin portion 500 and outer pin portion 600.
Interior pin portion 500 includes the first needle body 510 and the first housing 520.First needle body 510 includes needle body chamber 512 and pin
Mouth 514, needle body chamber 512 connect pin mouth 514.And the first housing 520 then connects the first needle body 510, and the first housing 520 includes
Housing cavity 522.Housing cavity 522 connects needle body chamber 512 and forms first chamber 530, and first chamber 530 is equipped with filler
And connection pin mouth 514.
Outer pin portion 600 is located on the outside in interior pin portion 500, and outer pin portion 600 includes the second needle body 610 and the second housing
620.Wherein the second needle body 610 is located on the outside of the first needle body 510, and blood back mouth 612 is opened on the second needle body 610.This
Outside, the second housing 620 connects the second needle body 610 and is located on the outside of the first housing 520.Perforate 622 is opened with switch portion 624
On the second housing 620.Furthermore between outer pin portion 600 and interior pin portion 500 formed second chamber 630, second chamber 630 with
First chamber 530 is isolated from each other, and second chamber 630 connects blood back mouth 612 and perforate 622.And switch portion 624 and Fig. 4 A, 4B
Switch portion 330 structure it is identical, repeat no more.In addition, the second housing 620 is as made by hard plastic, it can be transparent
Or it is translucent, and second housing 620 of the present embodiment is transparence, whether it can allow injector rapidly to differentiate has blood to enter
Enter among second chamber 630.Whereby, needle head structure 100a of the invention is formed special by interior pin portion 500 and outer pin portion 600
Annular chamber, it can be used to the situation for confirming blood back, and injector can be allowed to avoid filler from squeezing into blood vessel in injection and made
Into blood vessel embolism, the security of operation is significantly increased.
Fig. 8 is the schematic perspective view for the needle head structure 100b for illustrating further embodiment of this invention.This needle head structure 100b bags
Containing the first needle body 710, the first housing 720, the second needle body 730 and the second housing 740.Wherein the first needle body 710 includes first
The pin mouth 714 of needle body chamber 712 and first, the first needle body chamber 712 connects the first pin mouth 714, and the section of the first needle body 710 can
Rounded, oval, rectangle or polygon.First housing 720 connects the first needle body 710, and the first housing 720 includes first shell
Fluid chamber 722, the first needle body chamber 712 connect the first housing cavity 722 and form first chamber 702.Furthermore the second needle body
730 affixed first needle bodies 710, both are bonded each other, and the section of the second needle body 730 also can rounded, oval, rectangle or more
Side shape.Second needle body 730 includes the second needle body chamber 732 and the second pin mouth 734.Second needle body chamber 732 connects the second pin mouth
734, and the second pin mouth 734 is adjacent to the first pin mouth 714.In addition, the second housing 740 connects the second needle body 730, and the second housing
740 include the second housing cavity 742, perforate 744, switch portion 746 and housing wall 748.Second needle body chamber 732 connection second
Housing cavity 742 and form second chamber 704.First chamber 702 is isolated from each other with second chamber 704.First chamber 702 is equipped with
Filler, and second pin mouth of the connection of second chamber 704 734 and perforate 744.And switch portion 746 is installed on housing wall 748, and
Switch portion 746 can open or close perforate 744.Furthermore the transparent shape in the part of housing wall 748 of the second housing 740, it can allow note
Whether the person of penetrating rapidly differentiates has blood to enter among second chamber 704.The switch portion 746 of the present embodiment is lid, and it is pivotally connected
In the edge of housing wall 748.When switch portion 746 covers housing wall 748, second chamber 704 and extraneous air exclusion.And this
Switch portion 746 also can be manually mode manipulate.In addition it is noted that one end of the second needle body 730 can be in bending
Shape, that is, the second needle body 730 is in bending close to the position of the second housing 740.This forniciform structure can cause the first housing
720 bearing of trend intersects an angle with the bearing of trend of the second housing 740.This angle can be more than 10 degree and less than 90 degree.
And the angle of the present embodiment is 45 degree, the purpose is to allow the second housing 740 to have enough installation spaces, and angle is too small to make
First housing 720 and the second housing 740 at Operation switch portion 746 too close to easily causing inconvenience.Therefore, pin of the invention
Header structure 100b can not only confirm the situation of blood back under conditions of not pumpback, avoid filler from squeezing into blood vessel and cause blood vessel bolt
Fill in improve the security of operation, and it is easy to operate, allow injector more to favorably accomplish the injection course for the treatment of.
Fig. 9 is the side view for the needle head structure 100c for illustrating yet another embodiment of the invention.This needle head structure 100c includes pin
Body 800, housing 300 and separator 400.Coordinate and refer to Fig. 1, in Fig. 9 embodiment, housing 300 is divided equally with separator 400
It is not identical with separator 400 with housing in Fig. 3 300, repeat no more.Specifically, the needle head structure 100c of Fig. 9 embodiments is
Blunt needle, the front end of its needle body 800 is in arc-shaped.Wherein separator 400 is located in syringe needle cavity 102, and separator 400 is by syringe needle
Cavity 102 is separated out first chamber 410 and second chamber 420.First chamber 410 is isolated from each other with second chamber 420.And point
Pin mouth 220 is separated out injection port 430 and blood back mouth 440 by spacing body 400.First chamber 410 is equipped with filler and connection injection port
430, and second chamber 420 then connects blood back mouth 440 and perforate 320.Because pin mouth 220 is located at the side of front end, therefore inject
Mouth 430 is opened in the side of the front end of needle body 800 with blood back mouth 440.It is noted that separator 400 is close to pin mouth 220
Still have between front end and injection port 430 one intersegmental every injection fillers thing can be allowed blood back situation while to be carried out with monitoring.In addition,
If the front end of separator 400 trims with injection port 430, when operating needle head structure 100c injection port may occur for injector
430 in the blood vessels and blood back mouth 440 in EV situation, and the present embodiment can avoid this situation from occurring.Whereby, syringe needle knot
Structure 100c has a disconnected first chamber 410 and second chamber 420, and first chamber 410 is equipped with filler, and second chamber
420 be that transparent and housing 300 is provided with perforate 320 and switch portion 330, to confirm the situation of blood back.Can when perforate 320 is opened
Blood back situation is confirmed, if when closing injection fillers thing can be avoided to enter second chamber 420.Overall structure can make injector in injection
When avoid filler from squeezing into blood vessel, and then improve the security of operation.
Figure 10 A are the side views for illustrating the needle head structure 100d of another embodiment of the present invention when confirming blood back.Figure 10 B are
Illustrate side views of Figure 10 A needle head structure 100d in injection.As illustrated, this needle head structure 100d includes needle body 200, shell
Body 300, separator 400a and conduit 900.This needle body 200 is prong.In Figure 10 A and Figure 10 B embodiment, needle body
200 is respectively identical with housing 300 with needle body in Fig. 2 200 with housing 300, repeats no more.Specifically, Figure 10 A and Figure 10 B
The needle head structure 100d of embodiment separator 400a is located in syringe needle cavity 102 and with the first lattice 402a, second
Syringe needle cavity 102 is separated out first chamber 410 and second chamber by lattice 404 and blood back mouth 440, this separator 400a
420.Blood back mouth 440 connects first chamber 410 and second chamber 420, and blood back mouth 440 is adjacent to pin mouth 220.Blood back mouth 440 is situated between
Between the first lattice 402a and the second lattice 404, and blood back mouth 440 has bore D3.First lattice 402a's
One end connects the inwall of needle body 200, and the other end then connects the inner edge of housing wall 340.Second lattice 404 is then located at needle body chamber
Room 210 and its side view is L-shaped.Carefully say, second chamber 420 connects the perforate 320 of blood back mouth 440 and housing 300, makes the
Two chambers 420 are between blood back mouth 440 and perforate 320.Blood back mouth 440 is separated by the first space D 1 with pin mouth 220.Furthermore lead
Pipe 900 has injection port 910 and tube wall 920, and this conduit 900 is displaceably arranged among first chamber 410 and equipped with filling
Thing.Tube wall 920 is identical with the shape of first chamber 410.When injector operates needle head structure 100d, two steps can be implemented.
First step is to confirm blood back situation, and in this step, conduit 900 is penetrated in first chamber 410 and allows note by injector
Loophole 910 is displaced to an ad-hoc location, causes the second space D 2 between injection port 910 and pin mouth 220 to be more than the first space D 1.
Now second chamber 420 is connected with pin mouth 220, and injector can be allowed to be confirmed whether to get to blood vessel by the situation of blood back, is such as schemed
Shown in 10A.Second step is then injection fillers thing, and in this step, injector can be first by conduit 900 toward the side of pin mouth 220
It is one intersegmental every making the second space D 2 between injection port 910 and pin mouth 220 be less than or equal to the first spacing to further promoting
D1, now conduit 900 the closing blood back of tube wall 920 mouth 440, make first chamber 410 be isolated from each other with second chamber 420.Then,
Filler in conduit 900 is injected at pin mouth 220 by injector, is finally extracted needle body 200 out and is completed injecting program.Such a knot
Structure can avoid filler from entering second chamber 420 when injection and be formed and be blocked, and can reduce the degree of difficulty of cleaning.It is worth in addition
One is mentioned that, after the completion of injection, conduit 900 can detach first chamber 410 and abandon and change, and needle body 200 kills in cleaning
Bacterium can reclaim use later, and coordinate another conduit 900 equipped with filler to continue to inject next time, such a structure and operation
Manufacturing cost, and easy to operate simple and safety can not only be reduced.Because filler belongs to sticky shape, general conventional injection
Needle head structure easily causes the blocking of filler and can not used, and the present invention can not only allow injector can smoothly and securely
The injection course for the treatment of is completed, can also be greatly reduced and be applied hitter's generation side effect or unexpected risk.
Figure 11 A are the side views for illustrating the needle head structure 100e of another embodiment of the present invention when confirming blood back.Figure 11 B are
Illustrate side views of Figure 11 A needle head structure 100e in injection.As illustrated, this needle head structure 100e includes needle body 200, shell
Body 300, separator 400b and conduit 900.In Figure 11 A and Figure 11 B embodiment, needle body 200, housing 300 and lead
Pipe 900 is respectively identical with needle body 200, housing 300 and conduit 900 in Figure 10 A, Figure 10 B, repeats no more.Specifically, scheme
The 11A and needle head structure 100e of Figure 11 B embodiments separator 400b has the first lattice 402b, the second lattice 404
And syringe needle cavity 102 is separated out first chamber 410 and second chamber 420 by blood back mouth 440, this separator 400b.In addition, the
First lattice 402as of the one lattice 402b compared with Figure 10 A is short, therefore Figure 11 A, 11B needle head structure 100e blood back mouth
440 bore D3 is more than Figure 10 A, the bore D3 of 10B needle head structure 100d blood back mouth 440.In other words, the first lattice
402b is only in housing 300, and the second lattice 404 close to pin mouth 220 is then located in needle body 200, the needle body of needle body 200
Chamber 210 has no the first lattice 402b.Under such structural condition, needle body 200 can be fabricated to thinner body, that is,
The smaller needle body 200 of caliber is can be made into, and then reduces needle body 200 and punctures caused wound size.In addition, when injector operates
During needle head structure 100e, it can equally implement two steps.First step is to confirm blood back situation, in this step, is injected
Conduit 900 is penetrated in needle body chamber 210 and allows injection port 910 to be displaced to an ad-hoc location by person, causes injection port 910 and pin mouth
The second space D 2 between 220 is more than the first space D 1.It can now be formed between the inwall of the outer wall of conduit 900 and needle body 200
One empty room 422, this empty room 422 belongs to a part for second chamber 420, and empty room 422 communicates with each other with pin mouth 220, can be with
Injector is allowed to be confirmed whether to get to blood vessel by the situation of blood back, as shown in Figure 11 A.Second step is then injection fillers thing,
In this step, injector first can further promote conduit 900 toward the direction of pin mouth 220 one intersegmental every making injection port 910
The second space D 2 between pin mouth 220 is less than or equal to the first space D 1, and now the tube wall 920 of conduit 900 closes blood back mouth
440, make empty room 422 be isolated from each other with pin mouth 220.Then, the filler in conduit 900 is injected at pin mouth 220 by injector.
Finally, when filler injection finishes, conduit 900 can be extracted needle body 200 and first chamber 410 and complete injecting program.
Such a structure can avoid filler from entering empty room 422 when injection and result in blockage, and can not only reduce the degree of difficulty of cleaning, and
And its respective outer side edges injection operation not only convenient and simple but also safety and stability in general injector.
Figure 12 A are the schematic diagrames for the needle head structure 100f insertion blood vessels 104 for illustrating yet another embodiment of the invention.Figure 12 B are
Illustrate schematic diagrames of Figure 12 A needle head structure 100f in injection.As illustrated, this needle head structure 100f includes needle body 200, shell
Body 300a, conduit 900, threaded portion 930, rotation section 940 and injection tube 950.Wherein needle body 200 can be blunt needle or prong, this
Embodiment is prong, and needle body 200 includes needle body chamber 210, pin mouth 220 and separator 400c, and needle body chamber 210 connects
Pin mouth 220, separator 400c are located at the inner edge of needle body chamber 210.Housing 300a connections needle body 200, and housing 300a includes shell
Fluid chamber 310, perforate 320 and housing wall 340.Perforate 320 connects housing cavity 310 and is arranged on housing wall 340, needle body
Chamber 210 connects housing cavity 310.Furthermore conduit 900 has injection port 910 and tube wall 920, conduit 900 is displaceably worn
In housing cavity 310 and needle body chamber 210 and filler is housed.Separator 400c is separated by the first space D 1 with pin mouth 220, and notes
Loophole 910 is separated by one second space D 2 with pin mouth 220.The needle head structure 100f of the present embodiment has no installing switch portion, and screw thread
Portion 930 is connected between conduit 900 and rotation section 940.One end connecting thread portion 930 of rotation section 940, the other end then connect note
Shooting cylinder 950.When injector rotary motion portion 940, conduit 900, threaded portion 930, rotation section 940 and injection tube 950 are synchronous
Rotation, causes the second space D 2 between injection port 910 and pin mouth 220 to be adjusted.In addition, in Figure 12 A embodiment, the
One space D 1 is less than the second space D 2, and separator 400c is separated with tube wall 920 and formed blood back mouth 440.Due to the pin of needle body 200
Mouth 220 is inserted among blood vessels 104, therefore blood can flow into housing cavity 310 by needle body chamber 210, and injector can pass through
Transparent or semitransparent housing 300a observes the situation of blood back, and learns that pin mouth 220 is had been located in blood vessel 104.Now inject
Person will stop injection filler, and change the position of injection, that is, change the position of pin mouth 220, to ensure that filler will not be noted
Enter in blood vessel 104 and cause blocking.And in Figure 12 B embodiment, the pin mouth 220 of needle body 200 inserts non-vascular tissue 106 and worked as
In, injector's rotary motion portion 940 and reduce the second space D 2.Non-vascular tissue 106 is the tissue of no blood vessel 104.When
When first space D 1 is more than or equal to the second space D 2, tube wall 920 connects separator 400c, so as to making blood back mouth 440 close, at this moment
Injector can injection filler into non-vascular tissue 106, significantly add the security of operation, thus for injector with
For patient, it may be said that be doctors and patients' doulbe-sides' victory.
Also referring to Figure 13 A, Figure 13 B, Figure 13 A are the outer pins for the needle head structure 100g for illustrating another embodiment of the present invention
The sectional view in portion 600.Figure 13 B are the side views for illustrating Figure 13 A needle head structure 100g in injection.As illustrated, this syringe needle
Structure 100g is to injection fillers thing simultaneously and monitors blood back situation, and includes interior pin portion 500 and outer pin portion 600.
Interior pin portion 500 includes the first needle body 510 and the first housing 520.First needle body 510 includes needle body chamber 512 and pin
Mouth 514, needle body chamber 512 connect pin mouth 514.And the first housing 520 then connects the first needle body 510, and the first housing 520 includes
Housing cavity 522.Housing cavity 522 connects needle body chamber 512 and forms first chamber 530, and first chamber 530 is equipped with filler
And connection pin mouth 514.In addition, outer pin portion 600 is located on the outside in interior pin portion 500, and outer pin portion 600 includes the second needle body 610
With the second housing 620.Wherein the second needle body 610 is located on the outside of the first needle body 510, and blood back mouth 612 is opened in the second pin
On body 610.Second housing 620 connects the second needle body 610 and is located on the outside of the first housing 520.In addition, the second housing 620
Close end 620a and distal portion 620b can be included.Close end 620a has two ends, and wherein one end connects the second needle body 610, another
End then connects distal portion 620b.Distal portion 620b front end interlocking close end 620a, and distal portion 620b is provided with perforate 622.It is interior
Pin portion 500 is displaceably positioned at close end 620a and distal portion 620b.Furthermore when interior pin portion 500 inserts outer pin portion 600,
Second chamber 630 is formed between outer pin portion 600 and interior pin portion 500, second chamber 630 is isolated from each other with first chamber 530.This reality
Apply example needle head structure 100g have no installing switch portion in the second housing 620, the second housing 620 be as made by hard plastic,
It can be transparent or translucent.Perforate 622 connects blood back mouth 612 by close end 620a with the second needle body 610, and it can allow note
Whether the person of penetrating rapidly differentiates has blood to enter among second chamber 630, and then deduces that second needle body 610 in outer pin portion 600 is
It is no to be inserted into blood vessel.In addition, when the first needle body 510 inserts the second needle body 610, injector can be by the filler in interior pin portion 500
It is injected at pin mouth 514, as shown in Figure 13 B.Whereby, needle head structure 100g of the invention passes through interior pin portion 500 and outer pin portion 600
The special construction formed confirms the situation of blood back, and injector can be allowed to avoid filler from squeezing into blood vessel in injection and made
Into blood vessel embolism, the security of operation is significantly increased.
Figure 13 C are the side views for the needle head structure 100h for illustrating further embodiment of this invention.This needle head structure 100h is included
Interior pin portion 500 and outer pin portion 600.Outer pin portion 600 includes the second needle body 610, the second housing 620, connecting seat 640 and injection group
Part 1000.Second housing 620 is provided with perforate 622.Wherein interior pin portion 500, the second needle body 610 and second housing 620 and Figure 13 A,
The structure in needle head structure 100g interior pin portion 500, the second needle body 610 and the second housing 620 is identical in Figure 13 B, repeats no more.It is special
Other to be, outer pin portion 600 also includes connecting seat 640 and injecting assembly 1000, and connecting seat 640 connects perforate 622 and connection the
Two housings 620.The connected mode of the housing 620 of connecting seat 640 and second is detachably connected or integrally connected, and the present embodiment
It is integrated connection.Connecting seat 640 is as made by hard plastic, and it can connect miscellaneous injecting assembly 1000, to arrange
Gas, arrange blood or cause negative pressure.In addition, injecting assembly 1000 connects connecting seat 640, that is, injecting assembly 1000 passes through connecting seat
640 the second housings 620 of connection.Injecting assembly 1000 includes injection housing 1010 and injection rod 1020.Injection housing 1010 is removable
Connect connecting seat 640 with unloading.Injection rod 1020 is then positioned at located at injection housing 1010 and displaceably in injection housing 1010.
When injection rod 1020 is promoted by injector, injecting assembly 1000 can provide impulse force to clean the second needle body 610 and the second housing
620 inside.In other words, when occurring if the situation of blood back, the structure that connecting seat 640 combines injecting assembly 1000 can be with
Remained blood is drained and allows needle head structure 100h to be continuing with, and then reduces the cost for changing syringe needle.
From above-mentioned embodiment, the present invention has following advantages：First, the needle head structure of the present invention can allow injection
Person is after needle point enters skin, and using the intravascular natural principle with pressure, needle point can be learnt by needing not move through pumpback
Whether in the blood vessels.Second, the needle head structure of the present invention has disconnected first chamber and second chamber, first chamber is equipped with
Filler, second chamber is transparent and has perforate, to confirm the situation of blood back.It can confirm blood back shape when perforate is opened
Condition, if when closing injection fillers thing can be avoided to enter second chamber, injector can be made to avoid filler from squeezing into blood vessel in injection
And blood vessel embolism is caused, and then improve the security of operation.Third, special needle head structure enables injector easily to operate,
Injector is allowed more to favorably accomplish the injection course for the treatment of.Fourth, the setting of special double-cavity structure collocation separator can reach
The effect of injection fillers thing and monitoring blood back situation simultaneously.Fifth, the present invention can both allow injector smooth and securely complete
Into the injection course for the treatment of, it can also reduce and be applied hitter's generation side effect or unexpected risk.Sixth, utilize connecting seat combination injecting assembly
Structure remained blood can be drained and allow needle head structure to be continuing with, and then reduce change syringe needle cost.
Although the present invention is disclosed as above with embodiment, so it is not limited to the present invention, and any this area is general
Technical staff, without departing from the spirit and scope of the present invention, when can be used for a variety of modifications and variations, therefore the protection of the present invention
Scope is worked as to be defined depending on what claim was defined.
Claims (11)
1. a kind of needle head structure, to injection fillers thing simultaneously and monitor blood back situation, it is characterised in that the needle head structure bag
Contain：
Needle body, comprising needle body chamber and pin mouth, the needle body chamber connects the pin mouth；
Housing, connects the needle body, and the housing includes housing cavity and perforate, housing cavity described in the needle body chamber
And form syringe needle cavity；And
Separator, in the syringe needle cavity, the syringe needle cavity is separated out first chamber and the second chamber by the separator
Room, the first chamber are isolated from each other with the second chamber, and the pin mouth is separated out injection port and blood back by the separator
Mouthful, the first chamber connects the blood back mouth and institute equipped with the filler and the connection injection port, the second chamber
State perforate.
2. needle head structure as claimed in claim 1, it is characterised in that the needle body is blunt needle or prong.
3. needle head structure as claimed in claim 1, it is characterised in that the housing is provided with switch portion, the switch portion opening and closing
The perforate.
4. a kind of needle head structure, to injection fillers thing simultaneously and monitor blood back situation, it is characterised in that the needle head structure bag
Contain：
Interior pin portion, comprising：
First needle body, comprising needle body chamber and pin mouth, the needle body chamber connects the pin mouth；And
First housing, first needle body is connected, first housing includes housing cavity, and the housing cavity connects the pin
Fluid chamber and form first chamber, the first chamber is equipped with the filler and the connection pin mouth；And
Outer pin portion, is located on the outside in the interior pin portion, and the outer pin portion includes perforate and blood back mouth, and the outer pin portion and institute
State and form second chamber between interior pin portion, the second chamber is isolated from each other with the first chamber.
5. needle head structure as claimed in claim 4, it is characterised in that the outer pin portion also includes：
Second needle body, is located on the outside of first needle body, and the blood back mouth is opened on second needle body；And
Second housing, connect second needle body and be located on the outside of first housing, the perforate is opened in described the
On two housings.
6. needle head structure as claimed in claim 5, it is characterised in that second needle body is blunt needle or prong.
7. needle head structure as claimed in claim 5, it is characterised in that
Second housing is provided with switch portion, and the switch portion is opened and closed the perforate；And
The second chamber connects the blood back mouth and the perforate.
8. needle head structure as claimed in claim 5, it is characterised in that second housing includes：
Close end, has two ends, and wherein one end connects second needle body；And
Distal portion, the other end at two end is connected, the perforate is in the distal portion；
Wherein described interior pin portion is displaceably positioned at the close end and the distal portion.
9. needle head structure as claimed in claim 5, it is characterised in that the outer pin portion also includes：
Connecting seat, connect the perforate and connection second housing；And
Injecting assembly, connects the connecting seat, and the injecting assembly includes：
Injection housing, the detachably connected connecting seat；And
Injection rod, it is positioned at located at the injection housing and displaceably in the injection housing.
10. needle head structure as claimed in claim 4, it is characterised in that the filler be sodium hyaluronate, calcium hydroxy apetite,
Polycaprolactone, collagen, PLLA, fat, polypropylene amine, Triamcinolone Acetonide or lidocaine.
11. a kind of needle head structure, to injection fillers thing simultaneously and monitor blood back situation, it is characterised in that the needle head structure
Comprising：
Needle body, comprising：
Needle body chamber；
Pin mouth, connect the needle body chamber；And
Separator, in the needle body chamber；
Housing, connects the needle body, and the housing includes housing cavity and perforate, housing chamber described in the needle body chamber
Room；And
Conduit, has injection port and a tube wall, the conduit be displaceably arranged in the housing cavity and the needle body chamber and
Equipped with the filler；
Wherein, the separator is separated by the first spacing with the pin mouth, and the injection port is separated by the second spacing with the pin mouth, when
Described first when being smaller than second spacing, and the separator separates with the tube wall and forms blood back mouth, when described
When one spacing is more than or equal to second spacing, the tube wall connects the separator, so as to making the blood back mouth close.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610279515 | 2016-04-29 | ||
| CN2016102795159 | 2016-04-29 | ||
| CN201610467211 | 2016-06-24 | ||
| CN2016104672115 | 2016-06-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107335114A true CN107335114A (en) | 2017-11-10 |
| CN107335114B CN107335114B (en) | 2020-06-05 |
Family
ID=60160654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611019932.6A Expired - Fee Related CN107335114B (en) | 2016-04-29 | 2016-11-18 | Needle head structure |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN107335114B (en) |
| WO (1) | WO2017185729A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108837238A (en) * | 2018-07-13 | 2018-11-20 | 江苏省人民医院（南京医科大学第附属医院） | Hyaluronic acid injection needle |
| CN109745598A (en) * | 2018-12-29 | 2019-05-14 | 温州市人民医院 | A kind of blood vessel alarm injection needle |
| CN110339431A (en) * | 2019-05-10 | 2019-10-18 | 刘金花 | A kind of cavity-separating syringe for medical cosmetology injection |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2017185729A1 (en) | 2017-11-02 |
| CN107335114B (en) | 2020-06-05 |
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