CN107335021A - A kind of pill medicine and preparation method for treating icteric hepatitis - Google Patents

A kind of pill medicine and preparation method for treating icteric hepatitis Download PDF

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Publication number
CN107335021A
CN107335021A CN201710650780.8A CN201710650780A CN107335021A CN 107335021 A CN107335021 A CN 107335021A CN 201710650780 A CN201710650780 A CN 201710650780A CN 107335021 A CN107335021 A CN 107335021A
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medicine
icteric hepatitis
treating
hepatitis
eupatorium
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夏瑜
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Sichuan Jintang Haina Biomedical Technology Institute
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Sichuan Jintang Haina Biomedical Technology Institute
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

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  • Health & Medical Sciences (AREA)
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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of pill medicine for treating icteric hepatitis provided according to the understanding mechanism of Chinese traditional treatment icteric hepatitis, each component and its mass parts ratio of the medicine are as follows：60~160g of oriental wormwood, 30~100g of granatum, 80~160g of wrinkled giant hyssop, 250~550g of purslane, 30~100g of eupatorium, 60~160g of Radix Angelicae Sinensis, 90~250g of wolf's milk, 30~100g of rhizoma atractylodis, 30~160g of the bighead atractylodes rhizome, 30~120g of root tuber of aromatic turmeric, 30~150g of monkshood, 150~600g of desmodium, 30~150g of radix glycyrrhizae；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of pill medicine and preparation method for treating icteric hepatitis
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for treating icteric hepatitis, particularly supply The pill medicine and the field of preparation method that jaundice type hepatitis patient uses.
Background technology
Motherland's medical science thinks：Icteric hepatitis, it is the hepatitis as caused by the various causes of disease, while with skin and mucosa xanthochromia, More than 17.1 μm ol/L persons of serum bilirubin are referred to as icteric hepatitis.Icteric hepatitis is to be based on whetheing there is jaundice performance and serum courage Whether red pigment level raises to define, and corresponding is anicteric hepatitis.Icteric hepatitis is a kind of clinical symptoms Diagnosis rather than etiological diagnosis.
So, just how to find it is a kind of imitate treatment jaundice type hepatitis Chinese medicine composition, be those skilled in the art urgently The problem of to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, on treatment jaundice type hepatitis, people gradually appreciate the traditional Chinese medical science The advantages for the treatment of jaundice type hepatitis, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing west The present situation for treating jaundice type hepatitis is cured, the purpose of the present invention is to be to provide a kind of pill medicine for treating icteric hepatitis, with Solve the problems, such as that jaundice type hepatitis patient gets well early.The medicine is using common Chinese medicine as raw material, by selecting rationally Medicine and mass parts ratio, can effectively treat above-mentioned jaundice type hepatitis.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats icteric hepatitis Pill medicine and preparation method, it is characterised in that each component and its mass parts of the medicine are than as follows：
60~160g of oriental wormwood, 30~100g of granatum, 80~160g of wrinkled giant hyssop, 250~550g of purslane, 30~100g of eupatorium, when Return 60~160g, 90~250g of wolf's milk, 30~100g of rhizoma atractylodis, 30~160g of the bighead atractylodes rhizome, 30~120g of root tuber of aromatic turmeric, monkshood 30~ 150g, 150~600g of desmodium, 30~150g of radix glycyrrhizae, appropriate starch.
A kind of pill medicine and preparation method for treating icteric hepatitis, it is characterised in that each component of the medicine And its mass parts are than as follows：
70~140g of oriental wormwood, 36~90g of granatum, 90~140g of wrinkled giant hyssop, 280~480g of purslane, 36~90g of eupatorium, Radix Angelicae Sinensis 70~140g, 100~220g of wolf's milk, 36~90g of rhizoma atractylodis, 36~140g of the bighead atractylodes rhizome, 36~105g of root tuber of aromatic turmeric, 36~130g of monkshood, 180~500g of desmodium, 36~130g of radix glycyrrhizae, appropriate starch.
A kind of pill medicine and preparation method for treating icteric hepatitis, it is characterised in that the medicine of " preferred plan " The each component and its mass parts of thing are than as follows：
Oriental wormwood 120g, granatum 80g, wrinkled giant hyssop 120g, purslane 420g, eupatorium 80g, Radix Angelicae Sinensis 120g, wolf's milk 200g, rhizoma atractylodis 80g, bighead atractylodes rhizome 120g, root tuber of aromatic turmeric 95g, monkshood 115g, desmodium 420g, radix glycyrrhizae 115g, appropriate starch.
A kind of pill medicine and preparation method for treating icteric hepatitis, it is characterised in that methods described includes following step Suddenly it is prepared：
A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and dried, it is ground into superfine end according to mass parts ratio and treats With；
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.7mm~4.0mm）, and then dry, sterilization, packing is close Envelope.
A kind of pill medicine and preparation method for treating icteric hepatitis, it is characterised in that the instructions of taking is：Will system The water pill medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, and dosage 6g/time, warm water delivery service.It is within 15 days One course for the treatment of, 3~5 courses for the treatment of of taking medicine, symptom disappear, and disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：
Oriental wormwood, nature and flavor：It is bitter, pungent, be slightly cold, have clearing away damp-heat, removing jaundice subcutaneous ulcer the effect of, for treat jaundice oliguria, wet sore itch, pass Metachromia icteric hepatitis；
Granatum, nature and flavor：It is sour, puckery, warm, there is relieving diarrhea with astringents, hemostasis, the effect of expelling parasite, for treat chronic diarrhea, protracted dysentery, have blood in stool, Prolapse of the anus, uterine bleeding, leukorrhea, abdominal pain due to enterositosis；
Wrinkled giant hyssop, nature and flavor：Pungent, tepor, have fast gas and in, ward off the effect of dirty, clearing damp, for treating flu summer-heat and damp, fever and chills, head Bitterly, the disease such as chest gastral cavity ruffian, vomiting and diarrhea, malaria, dysentery, halitosis；
Purslane, nature and flavor：It is sour, cold, there is the effect of clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body, for treating bacillary dysentery, acute stomach and intestine Furuncle swelling toxin, eczema, herpes zoster are controlled in inflammation, acute appendicitis, mastitis, hemorrhoid hemorrhage, leukorrhea, external application；
Eupatorium, nature and flavor：It is pungent, flat, have and remove dampness by means of aromatics, appetizing of being amusing, deliver the effect of relieving summer-heat, for treating turbi damp obstructing in middle-JIAO, gastral cavity Sweet, halitosis, polysialia, summer-heat and damp table disease, alliteration are uncomfortable in chest in ruffian evil of vomitting, mouth；
Radix Angelicae Sinensis, nature and flavor：It is sweet, pungent, bitter, warm-natured, there is the effect of enriching blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treating The all cards of the deficiency of blood, irregular menstruation, Amenorrhea, dysmenorrhoea, Disorder lumps in the abdomen knot are poly-, uterine bleeding, asthenia cold abdominalgia, Impotence numbness, numbness, intestines are dry and shit is difficult, red Weight, ulcer sores, injury from falling down after dysentery；
Wolf's milk, nature and flavor：It is pungent, flat, there is the effect of clearing heat and detoxicating, cooling blood and hemostasis, for treating dysentery, diarrhea, hemoptysis, urine Blood, have blood in stool, uterine bleeding, boil carbuncle swells；
Rhizoma atractylodis, nature and flavor：Acrid, bitter, warm, there is the effect of drying damp and strengthening spleen, expelling wind and clearing away cold, improving eyesight, for treating abdominal fullness and distention, letting out Rush down, the disease such as oedema, tinea pedis Wei lame, arthralgia pain due to rheumatism, anemofrigid cold, yctalopia；
The bighead atractylodes rhizome, nature and flavor：It is bitter, sweet, warm-natured, have strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, it is antiabortive the effect of, for treating temper The few abdominal distension of weakness, spiritlessness and weakness, deficiency of food, big loose stool are thin, fluid retention stagnating in the interior, difficult urination, oedema, phlegmatic vertigo, warm numbness are ached, gas The diseases such as empty spontaneous perspiration, fetal irritability；
Root tuber of aromatic turmeric, nature and flavor：It is acrid flavour, hardship, cold in nature, there is the effect of promoting blood circulation stops energy, promoting qi circulation and removing obstruction in the collateral, the cool blood that clears away heart-fire, soothing liver-gallbladder, be used for Treat all pains of chest and abdomen side of body rib, dysmenorrhes, Amenorrhea, Disorder lumps in the abdomen caking, pyreticosis coma, demented, frightened epilepsy, haematemesis, be defeated in battle standby, blood strangury, sand The diseases such as leaching, jaundice；
Monkshood, nature and flavor：Pungent, sweet, big heat, it is poisonous, have recuperating depleted yang, mends fire supporing yang, by wind-cold damp pathogen the effect of, for treating Yang depletion collapse, cold weak pulse of limb, impotence, Gong Leng, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, cold sensation of the genitalia oedema, deficiency of yang diseases caused by external factors, numbness and ache of cold dampness；
Desmodium, nature and flavor：It is sweet, salty, be slightly cold, have eliminating dampness and heat, it is treating stranguria, detumescence the effect of, for treating heat gonorrhea, Sha Lin, urine It is puckery have a pain, jaundice, carbuncle swells furunculosis, venomous snake bite, liver and bile stone, lithangiuria；
Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, the disease such as ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning.
Medicine of the present invention is the principle based on Chinese traditional treatment jaundice type hepatitis, from according to jaundice type hepatitis pathomechanism and Pharmacological action is thought：With regard to jaundice type hepatitis, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, to above-mentioned disease There is good therapeutic effect.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned jaundice type hepatitis, prepared using the formula Medicine effect it is good, it is quick, be a Chinese prescription treated both principal and secondary aspect of disease, be particularly suitable for Clinical practice.With reference to the present invention Embodiment be described in further detail：
Embodiment 1：
A kind of pill medicine for treating icteric hepatitis, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：
Oriental wormwood 120g, granatum 80g, wrinkled giant hyssop 120g, purslane 420g, eupatorium 80g, Radix Angelicae Sinensis 120g, wolf's milk 200g, rhizoma atractylodis 80g, bighead atractylodes rhizome 120g, root tuber of aromatic turmeric 95g, monkshood 115g, desmodium 420g, radix glycyrrhizae 115g, appropriate starch.
Embodiment 2：
A kind of pill medicine for treating icteric hepatitis, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：
Oriental wormwood 140g, granatum 90g, wrinkled giant hyssop 140g, purslane 480g, eupatorium 90g, Radix Angelicae Sinensis 140g, wolf's milk 220g, rhizoma atractylodis 90g, bighead atractylodes rhizome 140g, root tuber of aromatic turmeric 105g, monkshood 130g, desmodium 500g, radix glycyrrhizae 130g, appropriate starch.
Embodiment 3：
A kind of pill medicine for treating icteric hepatitis, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：
Oriental wormwood 160g, granatum 100g, wrinkled giant hyssop 160g, purslane 550g, eupatorium 100g, Radix Angelicae Sinensis 160g, wolf's milk 250g, rhizoma atractylodis 100g, bighead atractylodes rhizome 160g, root tuber of aromatic turmeric 120g, monkshood 150g, desmodium 600g, radix glycyrrhizae 150g, appropriate starch.
Model case
Through clinical conditions jaundice type hepatitis patient totally 1600, the age is 850 of more than 30 years old, and only 750 are 30 Year is following.1106 to be fully recovered in 1600 patients, effective 350, invalid 144.Total effective rate is up to 91%.

Claims (3)

  1. A kind of 1. pill medicine for treating icteric hepatitis, it is characterised in that each component and its mass parts ratio of the medicine It is as follows：
    60~160g of oriental wormwood, 30~100g of granatum, 80~160g of wrinkled giant hyssop, 250~550g of purslane, 30~100g of eupatorium, when Return 60~160g, 90~250g of wolf's milk, 30~100g of rhizoma atractylodis, 30~160g of the bighead atractylodes rhizome, 30~120g of root tuber of aromatic turmeric, monkshood 30~ 150g, 150~600g of desmodium, 30~150g of radix glycyrrhizae, appropriate starch.
  2. 2. the pill medicine for the treatment of icteric hepatitis according to claim 1, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：
    70~140g of oriental wormwood, 36~90g of granatum, 90~140g of wrinkled giant hyssop, 280~480g of purslane, 36~90g of eupatorium, Radix Angelicae Sinensis 70~140g, 100~220g of wolf's milk, 36~90g of rhizoma atractylodis, 36~140g of the bighead atractylodes rhizome, 36~105g of root tuber of aromatic turmeric, 36~130g of monkshood, 180~500g of desmodium, 36~130g of radix glycyrrhizae, appropriate starch.
  3. 3. according to claim 1 to 2 treatment icteric hepatitis pill medicine, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：
    Oriental wormwood 120g, granatum 80g, wrinkled giant hyssop 120g, purslane 420g, eupatorium 80g, Radix Angelicae Sinensis 120g, wolf's milk 200g, rhizoma atractylodis 80g, bighead atractylodes rhizome 120g, root tuber of aromatic turmeric 95g, monkshood 115g, desmodium 420g, radix glycyrrhizae 115g, appropriate starch.
CN201710650780.8A 2017-08-02 2017-08-02 A kind of pill medicine and preparation method for treating icteric hepatitis Withdrawn CN107335021A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107837373A (en) * 2017-12-22 2018-03-27 苏州斯尔斯特新材料科技有限公司 A kind of medicine for treating jaundice and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107837373A (en) * 2017-12-22 2018-03-27 苏州斯尔斯特新材料科技有限公司 A kind of medicine for treating jaundice and preparation method thereof

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Application publication date: 20171110