CN107320546A - A kind of no added notoginseng-red sage haw flakes and preparation method thereof - Google Patents

A kind of no added notoginseng-red sage haw flakes and preparation method thereof Download PDF

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Publication number
CN107320546A
CN107320546A CN201710703439.4A CN201710703439A CN107320546A CN 107320546 A CN107320546 A CN 107320546A CN 201710703439 A CN201710703439 A CN 201710703439A CN 107320546 A CN107320546 A CN 107320546A
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China
Prior art keywords
powder
notoginseng
red sage
added
hawthorn
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CN201710703439.4A
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Chinese (zh)
Inventor
赵爱
高明海
张兴城
游晓蕾
王朝梁
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WENSHAN UNIVERSITY
WENSHAN HUAXIN SANQI Co Ltd
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WENSHAN UNIVERSITY
WENSHAN HUAXIN SANQI Co Ltd
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Priority to CN201710703439.4A priority Critical patent/CN107320546A/en
Publication of CN107320546A publication Critical patent/CN107320546A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to Chinese medicinal tablet field, and in particular to a kind of no added notoginseng-red sage haw flakes and preparation method thereof;Including following raw material components:Radix Notoginseng powder, danshen powder and hawthorn powder, preparation method include step in detail below:A1, cleaning;A2, crushing;A3, mixing plasmid;A4, sieving;A5, baking;A6, tabletting;It is an object of the invention to provide a kind of no added notoginseng-red sage haw flakes and preparation method thereof, it uses traditional granulation, tablet forming technique, without other auxiliary materials, technique is simple, economical and efficient, and gained tablet is more green, health, and raw material Radix Notoginseng powder, danshen powder, the hawthorn powder of the present invention are all that piece agent is done after crushing, taken to easy in vivo and disperse by human body, each component functional component is easily leached, and can promote to absorb.

Description

A kind of no added notoginseng-red sage haw flakes and preparation method thereof
Technical field
The invention belongs to Chinese medicinal tablet field, and in particular to a kind of no added notoginseng-red sage haw flakes and its preparation side Method.
Background technology
Angiocardiopathy is one of the incidence of disease and the higher principal disease of case fatality rate in the world, and research data shows that Chinese medicine exists Treat and prevent cardiovascular and cerebrovascular disease and facilitate larger advantage and potentiality.
Pseudo-ginseng is Araliaceae, alias Panax pseudoginseng, pseudo-ginseng or Typhonium flagelliforme (Lodd.) Blume etc., is clinical conventional Chinese medicine.Pseudo-ginseng is sweet, Slight bitter, warm-natured, Return liver, stomach, the heart, small intestinl channel, with hemostasis, dissipate the stasis of blood, swelling and pain relieving the effects such as, modern pharmacological research prove its lead Active component arasaponin is wanted effectively to prevent cerebrovascular arteries atherosis.
The red sage root is the drying root and rhizome of the labiate red sage root, and cold in nature, bitter, thoughts of returning home warp, pericardium channel specially walk blood system, The effect of with promoting blood circulation and removing obstruction in channels, stasis-dispelling and pain-killing, cool blood to disappear carbuncle, relieving restlessness that clears away heart-fire.Modern medicine and clinical test show that the red sage root has expansion Open coronary artery, increase coronary blood flow, reducing heart rate, the effects such as improving myocardial anoxia.
Hawthorn is rose family may,《Compendium of Materia Medica》Record " hawthorn property acid is sweet, tepor ", " being longer than diet, be good for Taste, row tie gas, disappear extravasated blood ".It is the edible dual-purpose Chinese medicine of Ministry of Public Health's approval, it contains abundant nutriment, and modern medicine Pharmacological research confirms that triterpenes and flavonoids composition in hawthorn have cardiac stimulant, reducing blood lipid, hypotensive, atherosclerosis Deng effect.
In existing notoginseng-red sage haw flakes, in order to ensure tablet quality in production process, bonding generally needed to be added The pharmaceutic adjuvants such as agent, glidant, disintegrant, stabilizer could be prepared, and this not only adds cost, and many pharmaceutic adjuvants are all There is side effect, therefore develop a kind of simple production process, safety, economical and efficient, and the composite tablet without pharmaceutic adjuvant has weight Want meaning.
The content of the invention
In order to solve the above technical problems, the invention provides a kind of no added notoginseng-red sage haw flakes and its preparation side Method, it uses traditional granulation, tablet forming technique, without other auxiliary materials, and its technique is simple, and economical and efficient, gained tablet is greener Color, health.
The purpose of the present invention is achieved through the following technical solutions:
A kind of no added notoginseng-red sage haw flakes, including following raw material components:Radix Notoginseng powder, danshen powder and hawthorn powder.
Further, the ratio of weight and number of Radix Notoginseng powder, danshen powder and hawthorn powder is:1~3:1~2:1.
A kind of preparation method of no added notoginseng-red sage haw flakes, including step in detail below:
A1, cleaning
Pseudo-ginseng, the red sage root and hawthorn are cleaned with hair roll-type cleaning machine;
A2, crushing
Pseudo-ginseng, the red sage root, hawthorn crude drug are ground into superfine powder respectively through coarse crushing, crushing, ultralow temperature, obtain Radix Notoginseng powder, Danshen powder, hawthorn powder, it is standby;
A3, mixing plasmid
Radix Notoginseng powder, danshen powder, hawthorn powder obtained by A1 are obtained into mixed powder by more well mixed than row, added in the powder of mixing Ethanol, is mixed to raw material moistening;
A4, sieving
The material that step A3 is mixed obtains soft particle by 20-40 mesh sieves;
A5, baking
Soft particle after sieving is toasted, and is stirred once per 15min in baking process, is baked to moisture 7~12%, obtain dry Particle;
A6, tabletting
Dry particl obtained by step A5 is tabletted.
Further, in step A2 powder diameter more than 2000 mesh.
Further, in step A3, the ethanol of addition is the 5~20% of Radix Notoginseng powder, danshen powder and hawthorn powder weight sum.
Further, in step A3, the mass concentration for adding ethanol is 50~95%.
Further, the step A5 baking temperatures are 40 DEG C~60 DEG C.
Compared with prior art, the present invention one of at least has the following effects that:
1. being cleaned before crushing to pseudo-ginseng, the red sage root and hawthorn using hair roll-type cleaning machine, the removal of impurity can be effectively gone, a huge sum of money Category and agriculture are residual, improve edible security.
2. shorten the production cycle;In traditional tablet manufacturing technique, many tablets have art for coating(Including in particle It is coated and outer coatings), the present invention need not be coated, directly in blocks, and the production cycle is shortened to a certain extent, production is improved Efficiency.
3. it is more conducive to absorption of human body;Raw material Radix Notoginseng powder, danshen powder, the hawthorn powder of the present invention is all to be done after crushing in flakes Agent, is taken to easy in vivo by human body and disperses, each component functional component is easily leached, and reaches that promotion absorbs.
4. the present invention is on the basis of existing tablet, alcohol is only added, and alcohol can volatilize in baking and be lost in, In whole process, equivalent to without other auxiliary materials, a kind of more green, more healthy tablet can be made.
Embodiment
The essentiality content of the present invention is expanded on further below by way of instantiation, but protection scope of the present invention is simultaneously These examples are not limited to, the scope of the present invention is belonged to according to the improvement that the essence of the present invention is carried out to the present invention.
Embodiment 1
A kind of no added notoginseng-red sage haw flakes, including following raw material components:Radix Notoginseng powder, danshen powder and hawthorn powder, pass through three The compatibility between Chinese medicine is planted, enables to nutritive value higher.
Embodiment 2
On the basis of embodiment 1, the ratio of weight and number of Radix Notoginseng powder, danshen powder and hawthorn powder is:1:1:1, by three kinds of Chinese herbal medicines Rational proportion, can increase nutritive value.
Embodiment 3
On the basis of embodiment 1, the ratio of weight and number of Radix Notoginseng powder, danshen powder and hawthorn powder is:2:1:1, mixed under this ratio Close, obtained notoginseng-red sage haw flakes nutritive value is higher, and good absorbing effect, can have preferably to angiocardiopathy Therapeutic effect.
Embodiment 4
On the basis of embodiment 1, the ratio of weight and number of Radix Notoginseng powder, danshen powder and hawthorn powder is:3:2:1, mixed under this ratio Close, obtained notoginseng-red sage haw flakes nutritive value is higher, and good absorbing effect.
Embodiment 5
On the basis of embodiment 1-4, a kind of preparation method of no added notoginseng-red sage haw flakes, including walk in detail below Suddenly:
A1, cleaning
Pseudo-ginseng, the red sage root and hawthorn are cleaned with hair roll-type cleaning machine;
A2, crushing
Pseudo-ginseng, the red sage root, hawthorn crude drug are ground into superfine powder respectively through coarse crushing, crushing, ultralow temperature, obtain Radix Notoginseng powder, Danshen powder, hawthorn powder, it is standby;
A3, mixing plasmid
Radix Notoginseng powder, danshen powder, hawthorn powder obtained by A2 are obtained into mixed powder by more well mixed than row, added in the powder of mixing Ethanol, is mixed to raw material moistening;
A4, sieving
The material that step A3 is mixed obtains soft particle by 20-40 mesh sieves;
A5, baking
Soft particle after sieving is toasted, and is stirred once per 15min in baking process, is baked to moisture 7~12%, obtain dry Particle;
A6, tabletting
Dry particl obtained by step A5 is tabletted.
Pseudo-ginseng, the red sage root and hawthorn are cleaned using hair roll-type cleaning machine before crushing, the removal of impurity can be effectively gone, weight Metal and agriculture are residual, improve edible security, in traditional tablet manufacturing technique, many tablets have art for coating(Including It is coated and outer coatings in particle), the present invention need not be coated, directly in blocks, and the production cycle is shortened to a certain extent, be lifted Production efficiency;Stirred once per 15min in baking process, particle shape can be protected.
Embodiment 6
On the basis of embodiment 1-5, powder diameter does piece agent, quilt more than 2000 mesh after crushing in step A2 Human body takes easily scattered in vivo, and each component functional component is easily leached, and reaches that promotion absorbs.
Embodiment 7
On the basis of embodiment 1-6, the ethanol of addition is the 5% of Radix Notoginseng powder, danshen powder and hawthorn powder weight sum, adds ratio The suitable alcohol of example, enables to that sliver phenomenon will not be produced when compressed tablets.
Embodiment 8
On the basis of embodiment 1-6, the ethanol of addition is the 15% of Radix Notoginseng powder, danshen powder and hawthorn powder weight sum, can be made Obtain in mixing, reach that gently holding agglomerating, hand touches i.e. scattered state.
Embodiment 9
On the basis of embodiment 1-6, the ethanol of addition is the 20% of Radix Notoginseng powder, danshen powder and hawthorn powder weight sum, adds ratio The suitable alcohol of example, enables to that sliver phenomenon will not be produced when compressed tablets.
Embodiment 10
On the basis of embodiment 1-9, the mass concentration for adding ethanol is 50%, enables to, in mixing, reach and gently hold into Group, hand touch i.e. scattered state.
Embodiment 11
On the basis of embodiment 1-9, the mass concentration for adding ethanol is 65%, adds the concentration of ethanol, influences the tablet being made Quality, under this concentration of alcohol, the tablet smoothness of preparation is higher.
Embodiment 12
On the basis of embodiment 1-9, the mass concentration for adding ethanol is 95%, adds the concentration of ethanol, influences the tablet being made Quality, under this concentration of alcohol, the tablet smoothness of preparation is higher.
Embodiment 13
On the basis of embodiment 1-12, baking temperature is 40 DEG C, and under this baking temperature, the tablet moisture of preparation can exist Control is 7~12%, and alcohol can volatilize in baking and be lost in, in whole process, equivalent to without other auxiliary Material, can make a kind of more green, more healthy tablet.
Embodiment 14
On the basis of embodiment 1-12, baking temperature is 50 DEG C, and under this baking temperature, the tablet moisture of preparation can exist Control is 7~12%, and alcohol can volatilize in baking and be lost in, in whole process, equivalent to without other auxiliary Material, can make a kind of more green, more healthy tablet.
Embodiment 15
On the basis of embodiment 1-12, baking temperature is 60 DEG C, and under this baking temperature, the tablet moisture of preparation can exist Control is 7~12%, and alcohol can volatilize in baking and be lost in, in whole process, equivalent to without other auxiliary Material, can make a kind of more green, more healthy tablet.
Pseudo-ginseng, the red sage root and hawthorn are cleaned using hair roll-type cleaning machine before crushing, the removal of impurity can be effectively gone, weight Metal and agriculture are residual, improve edible security;Shorten the production cycle;In traditional tablet manufacturing technique, many tablets have Art for coating(Including being coated and outer coatings in particle), the present invention need not be coated, directly in blocks, shorten to a certain extent Production cycle, improve production efficiency;More conducively absorption of human body;Raw material Radix Notoginseng powder, danshen powder, the hawthorn powder of the present invention be all through Piece agent is done after crossing crushing, is taken to easy in vivo and disperses by human body, each component functional component is easily leached, and reaches that promotion absorbs; The present invention is on the basis of existing tablet, only to add alcohol, and alcohol can volatilize in baking and be lost in, in whole process In, equivalent to without other auxiliary materials, a kind of more green, more healthy tablet can be made.
Although reference be made herein to invention has been described for multiple explanatory embodiments of the invention, however, it is to be understood that Those skilled in the art can be designed that a lot of other modification and embodiment, and these modifications and embodiment will fall in this Shen Please be within disclosed spirit and spirit.More specifically, can be to master in the range of disclosure and claim The building block and/or layout for inscribing composite configuration carry out a variety of variations and modifications.Except what is carried out to building block and/or layout Outside modification and improvement, to those skilled in the art, other purposes also will be apparent.

Claims (7)

1. a kind of no added notoginseng-red sage haw flakes, it is characterised in that:Including following raw material components:Radix Notoginseng powder, danshen powder and Hawthorn powder.
2. a kind of no added notoginseng-red sage haw flakes according to claim 1, it is characterised in that:Radix Notoginseng powder, danshen powder Ratio of weight and number with hawthorn powder is:1~3:1~2:1.
3. a kind of preparation method of no added notoginseng-red sage haw flakes according to claim 1 or 2, it is characterised in that: Including step in detail below:
A1, cleaning
Pseudo-ginseng, the red sage root and hawthorn are cleaned with hair roll-type cleaning machine;
A2, crushing
Pseudo-ginseng, the red sage root, hawthorn crude drug are ground into superfine powder respectively through coarse crushing, crushing, ultralow temperature, obtain Radix Notoginseng powder, Danshen powder, hawthorn powder, it is standby;
A3, mixing plasmid
Radix Notoginseng powder, danshen powder, hawthorn powder obtained by A2 are obtained into mixed powder by more well mixed than row, added in the powder of mixing Ethanol, is mixed to raw material moistening;
A4, sieving
The material that step A3 is mixed obtains soft particle by 20-40 mesh sieves;
A5, baking
Soft particle after sieving is toasted, and is stirred once per 15min in baking process, is baked to moisture 7~12%, obtain dry Particle;
A6, tabletting
Dry particl obtained by step A5 is tabletted.
4. a kind of preparation method of no added notoginseng-red sage haw flakes according to claim 3, it is characterised in that:In step Powder diameter is more than 2000 mesh in rapid A2.
5. a kind of preparation method of no added notoginseng-red sage haw flakes according to claim 3, it is characterised in that:In step In rapid A3, the ethanol of addition is the 5~20% of Radix Notoginseng powder, danshen powder and hawthorn powder weight sum.
6. a kind of preparation method of no added notoginseng-red sage haw flakes according to claim 3, it is characterised in that:In step In rapid A3, the mass concentration for adding ethanol is 50~95%.
7. a kind of preparation method of no added notoginseng-red sage haw flakes according to claim 3, it is characterised in that:It is described Step A5 baking temperatures are 40 DEG C~60 DEG C.
CN201710703439.4A 2017-08-16 2017-08-16 A kind of no added notoginseng-red sage haw flakes and preparation method thereof Pending CN107320546A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112076269A (en) * 2020-06-24 2020-12-15 王宇 Auxiliary medicine for treating cardiovascular diseases
CN113455604A (en) * 2021-07-29 2021-10-01 文山学院 Pseudo-ginseng extract and application thereof in functional beverage
WO2022161177A1 (en) * 2021-01-26 2022-08-04 四川福生源科技有限公司 Traditional chinese medicine composition with sleep improving effect, and preparation method therefor and use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101332212A (en) * 2007-09-30 2008-12-31 张雪峰 Aweto micropowder tablet and preparation method thereof
CN104257710A (en) * 2014-10-21 2015-01-07 通化臻尊生物科技有限公司 Preparation method of pure wild ginseng powder buccal tablet with pure taste, rich nutrients and good adsorption
CN104783088A (en) * 2015-03-26 2015-07-22 赵君 Preparation method for pure Lycium ruthenicum Murr powder tablet and pure Lycium ruthenicum Murr powder tablet
CN106265873A (en) * 2016-08-25 2017-01-04 刘根喜 A kind of Radix Astragali pure powder tablet and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101332212A (en) * 2007-09-30 2008-12-31 张雪峰 Aweto micropowder tablet and preparation method thereof
CN104257710A (en) * 2014-10-21 2015-01-07 通化臻尊生物科技有限公司 Preparation method of pure wild ginseng powder buccal tablet with pure taste, rich nutrients and good adsorption
CN104783088A (en) * 2015-03-26 2015-07-22 赵君 Preparation method for pure Lycium ruthenicum Murr powder tablet and pure Lycium ruthenicum Murr powder tablet
CN106265873A (en) * 2016-08-25 2017-01-04 刘根喜 A kind of Radix Astragali pure powder tablet and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112076269A (en) * 2020-06-24 2020-12-15 王宇 Auxiliary medicine for treating cardiovascular diseases
WO2022161177A1 (en) * 2021-01-26 2022-08-04 四川福生源科技有限公司 Traditional chinese medicine composition with sleep improving effect, and preparation method therefor and use thereof
CN113455604A (en) * 2021-07-29 2021-10-01 文山学院 Pseudo-ginseng extract and application thereof in functional beverage

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Application publication date: 20171107

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