CN107279923A - ginseng composite fermentation nutrient powder and preparation method thereof - Google Patents

ginseng composite fermentation nutrient powder and preparation method thereof Download PDF

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Publication number
CN107279923A
CN107279923A CN201710559771.8A CN201710559771A CN107279923A CN 107279923 A CN107279923 A CN 107279923A CN 201710559771 A CN201710559771 A CN 201710559771A CN 107279923 A CN107279923 A CN 107279923A
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parts
ginseng
preparation
powder
composite fermentation
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曲迪
孙印石
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Institute Special Animal and Plant Sciences CAAS
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L25/00Food consisting mainly of nutmeat or seeds; Preparation or treatment thereof
    • A23L25/30Mashed or comminuted products, e.g. pulp, pastes, meal, powders; Products made therefrom, e.g. blocks, flakes, snacks; Liquid or semi-liquid products
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/13Fermented milk preparations; Treatment using microorganisms or enzymes using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/13Fermented milk preparations; Treatment using microorganisms or enzymes using additives
    • A23C9/1315Non-milk proteins or fats; Seeds, pulses, cereals or soja; Fatty acids, phospholipids, mono- or diglycerides or derivatives therefrom; Egg products
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/16Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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    • A23L19/01Instant products; Powders; Flakes; Granules
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/10Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10Cereal-derived products
    • A23L7/104Fermentation of farinaceous cereal or cereal material; Addition of enzymes or microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10Cereal-derived products
    • A23L7/198Dry unshaped finely divided cereal products, not provided for in groups A23L7/117 - A23L7/196 and A23L29/00, e.g. meal, flour, powder, dried cereal creams or extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23PSHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00Shaping or working of foodstuffs characterised by the products
    • A23P10/30Encapsulation of particles, e.g. foodstuff additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The present invention relates to nutritional health food field, in particular to a kind of ginseng composite fermentation nutrient powder and preparation method thereof.In parts by weight, the Nutrious fermented powder is mainly prepared by following material component:25~35 parts of 10~20 parts of ginseng, 15~20 parts of coix seed, 20~30 parts of Chinese yam, 5~10 parts of jujube, 5~10 parts of matrimony vine, 20~30 parts of walnut and Semen sesami nigrum.The preparation method of the Nutrious fermented powder is, by primary raw material water refluxing extraction, to be obtained again by spray drying after lactobacillus-fermented.The Nutrious fermented powder is formed by several raw material compoundings with health-care efficacy, with certain health-care efficacy, no toxicity;Using microcapsules technology, ginseng composite fermentation nutrient powder is made, meal replacing food can be done, hot water is taken after mixing it with water, convenient and swift;Can be effectively antifatigue, make one, with satiety, to alleviate sub-health state.

Description

Ginseng composite fermentation nutrient powder and preparation method thereof
Technical field
The present invention relates to nutritional health food field, in particular to a kind of ginseng composite fermentation nutrient powder and its system Preparation Method.
Background technology
Ginseng is the dry root of Araliaceae ginseng (Panax ginseng C.A.Mey), is traditional rare Chinese medicine, is begun It is loaded in first monograph on materia medica of China《Sheng Nong's herbal classic》.Its grower is referred to as " garden ginsent ", and wild survivor is referred to as " wild ginseng ".Ginseng has Have reinforce vital energy, veins takes off admittedly, the function reinforce the spleen to benefit the lung, promote the production of body fluid, calming the nerves, for it is physically weak to be taken off, cold weak pulse of limb, spleen eating less, The deficiency syndrome of the lung is breathed with cough, injury thirst, Heat Diabetes, thin prolonged illness void, insomnia of palpitating with fear, impotence Gong Leng, heart failure, cardiogenic shock etc. Treatment.Li Shizhen (1518-1593 A.D.) exists《Compendium of Materia Medica》In also ginseng is extremely praised highly, it is believed that it can be controlled " all chronic diseases marked by deficiency of vital energy of male woman ".For thousands of years, Ginseng is all listed in " top grade " in Chinese herbal medicine.Ginseng is usually used in more afterwards recovering, adjusts hormone, reduction blood glucose, enhancing muscle power, control Liver index and liver function health care processed etc..
Ginseng composite product on the market has much at present, but on the one hand due to compatibility relationship not science and so that its health care Effect is not notable, on the other hand biases toward medicinal existing product more, and mouthfeel is poor and edible not very convenient, is unfavorable for ginseng Product further processing and popularization.Microcapsules technology refers to be rolled into some active components by certain process meanses micro- The method of small closing particle.The maximum feature of microencapsulation material is effective existence for changing material, be easy to process, store and Transport;Effectively protection bioactive ingredients and sensitive composition, extend its shelf-life;Reduce or cover the bad taste of some compositions Road, reduces toxicological effect of additive etc. etc.., not only can be with if microcapsules technology can be applied in the processing of ginseng product Health, the production technology of nutrient and healthcare products and formula are provided, good economic benefit is obtained, moreover it is possible to the nutrition of long-term holding ginseng Composition, improves its mouthfeel, and can more easily be eaten,.
In view of this, it is special to propose the present invention.
The content of the invention
The first object of the present invention is to provide a kind of ginseng composite fermentation alimentation composition, and described composition, which has, to be protected Strong effect is good, the advantages of without obvious toxicity.
In order to realize the above-mentioned purpose of the present invention, spy uses following technical scheme:
The present invention relates to a kind of ginseng composite fermentation nutrient powder, in parts by weight, mainly it is prepared into by following material component Arrive:
10~20 parts of ginseng, 15~20 parts of coix seed, 20~30 parts of Chinese yam, 5~10 parts of jujube, 5~10 parts of matrimony vine, walnut 20~30 parts and 25~35 parts of Semen sesami nigrum.
The present invention is formed by several raw material compoundings with health-care efficacy, and technique preparation is handled by fermentation, with one Fixed health-care efficacy, no toxicity;Using microcapsules technology, ginseng composite fermentation nutrient powder is made, meal replacing food can be done, heat Mixing in water for oral taking, it is convenient and swift;Can be effectively antifatigue, make one, with satiety, to alleviate sub-health state.
The second object of the present invention is the preparation method for providing ginseng composite fermentation nutrient powder as described above, including:
1) ginseng, coix seed, Chinese yam, jujube, matrimony vine are smashed mixing by, are added water and are heated to reflux extraction, by obtained extraction Liquid carries out sterilization treatment after being mixed with milk powder and obtains fermentation raw material;
2) is fermented lactobacillus inoculum into the fermentation raw material, and obtained tunning is dried and is made Powder, into the powder, addition walnut, Semen sesami nigrum and flour are produced.
Compared with prior art, beneficial effects of the present invention are:
(1) good health care effect, it is raw materials used have must health-care efficacy, without obvious toxicity;
(2) with microencapsulation form preparation, instant, effect is good;
(3) it can be taken for meal, and can be effectively antifatigue, alleviate sub-health state.
Embodiment
One aspect of the present invention is related to a kind of ginseng composite fermentation nutrient powder, in parts by weight, mainly by following material component Prepare:
10~20 parts of ginseng, 15~20 parts of coix seed, 20~30 parts of Chinese yam, 5~10 parts of jujube, 5~10 parts of matrimony vine, walnut 20~30 parts and 25~35 parts of Semen sesami nigrum.
It is preferred that, ginseng composite fermentation nutrient powder as described above in parts by weight, is mainly prepared by following material component Obtain:
13~17 parts of ginseng, 16~19 parts of coix seed, 23~27 parts of Chinese yam, 6~9 parts of jujube, 6~9 parts of matrimony vine, walnut 23 ~27 parts and 28~32 parts of Semen sesami nigrum.
It is preferred that, ginseng composite fermentation nutrient powder as described above in parts by weight, is mainly prepared by following material component Obtain:
14~16 parts of ginseng, 17~18 parts of coix seed, 24~26 parts of Chinese yam, 7~8 parts of jujube, 7~8 parts of matrimony vine, walnut 24 ~26 parts and 29~31 parts of Semen sesami nigrum.
Ginseng is the root of Araliaceae herbaceos perennial ginseng (Panax ginseng C.A.Mey.), sweet slight bitter, temperature. With reinforcing vital energy, veins takes off admittedly reinforces the spleen to benefit the lung, and promotes the production of body fluid to quench thirst, effect of tranquilize the mind and promote the intelligence.Cure mainly:Internal lesion caused by overexertion is deficient, deficiency of food, tired Idle, regurgitation and emesis, stool lingering diarrhea, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition, quench one's thirst, women Uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, the disease of all qi-blood-body fluid deficiencies.
Coix seed is the benevolence of grass Job's tears.It is sweet;It is light;It is slightly cold.Diarrhea is controlled, arthritis with fixed pain caused by dampness, muscle arteries and veins contraction is bent and stretched not Profit, oedema, tinea pedis, consumptive lung disease, lung carbuncle, acute appendicitis, stranguria with turbid discharge, leukorrhea.
Chinese yam is the stem tuber of Dioscoreaceae plant Chinese yam.Splenasthenic diarrhea is cured mainly, protracted dysentery, cough due to consumptive disease is quenched one's thirst, under seminal emission, band, Frequent urination.
Jujube is the dry mature fruit of Rhamnaceae plant jujube.The empty deficiency of food of stomach is cured mainly, the weak loose stool of spleen, qi-blood-body fluid is not enough, It is disharmony between ying and wei, palpitation and severe palpitation.Married woman's stolen goods are hot-tempered.
Matrimony vine is the ripening fruits of matrimony vine of solanaceae plant or lycium barbarum.Liver-kidney Yin deficiency is cured mainly, soreness and weakness of waist and knees is dizzy, mesh Dizzy, many tears of blurred vision, cough due to consumptive disease is quenched one's thirst, seminal emission.
Walnut is juglandaceae plant English walnut Juglans regia L. dry mature seed.Cure mainly kidney deficiency and breathe heavily and cough, pain in the back Flaccidity of lower limbs, impotence, seminal emission, frequent urination, urolithiasis, dry feces.
Semen sesami nigrum is Pedaliaceae plant sesame Sesamum indicum L. seed.Cure mainly kidney deficiency and liver, empty wind dizziness, Wandering arthritis, paralysis, dry feces, thin, poliosis empty after being ill, married woman's breast are few.
The present invention by above-mentioned component by carrying out compatibility, and technique preparation is handled by fermentation, can be with antifatigue, and system Property be directed to the patient of hot sign, inferior health and its related chronic disease are effectively treated, so as to reach health care Purpose.
In a preferred embodiment, the material component for the ginseng composite fermentation nutrient powder that the present invention is provided also is wrapped Include:
The parts by weight of milk powder 40~50;Or 42~48 parts by weight;Or 44~46 parts by weight;
It is preferred that the milk powder is skimmed milk power.
In a preferred embodiment, the material component for the ginseng composite fermentation nutrient powder that the present invention is provided also is wrapped Include:
The parts by weight of flour 20~30;Or 22~28 parts by weight;Or 24~26 parts by weight.
The invention further relates to the preparation method of the preparation method of ginseng composite fermentation nutrient powder, including:
1) ginseng, coix seed, Chinese yam, jujube, matrimony vine are smashed mixing by, are added water and are heated to reflux extraction, by obtained extraction Liquid carries out sterilization treatment after being mixed with milk powder and obtains fermentation raw material;
2) is fermented lactobacillus inoculum into the fermentation raw material, and obtained tunning is dried and is made Powder, into the powder, addition walnut, Semen sesami nigrum and flour are produced.
It is preferred that, preparation method as described above, in step 1) in, the ginseng, coix seed, Chinese yam, jujube, matrimony vine Gross mass and the solid-to-liquid ratio of the water are 1:(8~12), more preferably 1:(9~11);More preferably 1:10.
It is preferred that, preparation method as described above, in step 1) in, it is described to be heated to reflux extraction and be specially:
Refluxing extraction 1.5h~2.5h under conditions of 55 DEG C~65 DEG C, extraction merges leaching liquor afterwards twice;
It is furthermore preferred that in step 1) in, it is described to be heated to reflux extraction and be specially:
Refluxing extraction 1.8h~2.2h under conditions of 58 DEG C~62 DEG C, extraction merges leaching liquor afterwards twice;
It is furthermore preferred that in step 1) in, it is described to be heated to reflux extraction and be specially:
Refluxing extraction 1.9h~2.1h under conditions of 59 DEG C~61 DEG C, extraction merges leaching liquor afterwards twice.
It is preferred that, preparation method as described above, the lactic acid bacteria is inoculated into the fermentation by 3~5wt% inoculum concentration Fermented in raw material, 40 DEG C~44 DEG C fermentation 6h~10h;
Wherein, in the mixed culture fermentation agent, the viable count of the lactic acid bacteria is 1 × 108~10CFU/g;
Fermented it is furthermore preferred that the lactic acid bacteria is inoculated into the fermentation raw material by 4wt% inoculum concentration, 41 DEG C~ 43 DEG C of fermentation 7h~9h;
Wherein, in the mixed culture fermentation agent, the viable count of the lactic acid bacteria is 1 × 109CFU/g。
It is preferred that, preparation method as described above, in step 2) in, the drying is spray drying;It is preferred that carrying out institute When stating spray drying, EAT is 180 DEG C~200 DEG C;It is furthermore preferred that 190 DEG C.
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the present invention.It is unreceipted specific in embodiment Condition person, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or the unreceipted production firm person of instrument, be The conventional products obtained can be bought by city.
Embodiment 1
A kind of processing method of ginseng composite fermentation nutrition powder capsule is present embodiments provided, by ginseng 10g, coix seed 20g, Chinese yam 20g, jujube 5g, matrimony vine 10g smash mixing, plus pure water, and solid-to-liquid ratio is 1:10, flow back and carry under conditions of 65 DEG C 1.5h is taken, is extracted twice, solid is abandoned in filtering, skimmed milk power 40g is added in the solution after filter mixed liquor, 121 DEG C of sterilizings is made 20min.The lactic acid bacteria for activating, having tamed is enlarged culture leavening is made, be inoculated with leavening by 3wt% inoculum concentration Fermented into mixed liquor, 44 DEG C of fermentation 6h obtain the complex lactic acid fermented liquid of ginseng;It is described in the mixed culture fermentation agent The viable count equal 1 × 10 of lactic acid bacteria9CFU/g.The complex lactic acid fermented liquid debita spissitudo of ginseng is adjusted, is spray-dried, air intake Temperature is 180 DEG C.The walnut 30g ground, Semen sesami nigrum 25g and flour are added into the ginseng composite fermentation microcapsules gushed out 30g is nutrient powder finished product.
Embodiment 2
A kind of processing method of ginseng composite fermentation nutrition powder capsule is present embodiments provided, by ginseng 20g, coix seed 15g, Chinese yam 30g, jujube 10g, matrimony vine 5g smash mixing, plus pure water, and solid-to-liquid ratio is 1:10, flow back and carry under conditions of 55 DEG C 2.5h is taken, is extracted twice, solid is abandoned in filtering, skimmed milk power 50g is added in the solution after filter mixed liquor, 121 DEG C of sterilizings is made 20min.The lactic acid bacteria for activating, having tamed is enlarged culture leavening is made, be inoculated with leavening by 5wt% inoculum concentration Fermented into mixed liquor, 40 DEG C of fermentation 10h obtain the complex lactic acid fermented liquid of ginseng;It is described in the mixed culture fermentation agent The viable count of lactic acid bacteria is 1 × 109CFU/g.The complex lactic acid fermented liquid debita spissitudo of ginseng is adjusted, is spray-dried, air intake Temperature is 200 DEG C.The walnut 20g ground, Semen sesami nigrum 35g and flour are added into the ginseng composite fermentation microcapsules gushed out 20g is nutrient powder finished product.
Embodiment 3
A kind of processing method of ginseng composite fermentation nutrition powder capsule is present embodiments provided, by ginseng 15g, coix seed 17g, Chinese yam 25g, jujube 7g, matrimony vine 7g smash mixing, plus pure water, and solid-to-liquid ratio is 1:10, flow back and carry under conditions of 60 DEG C 2h is taken, is extracted twice, solid is abandoned in filtering, skimmed milk power 45g is added in the solution after filter mixed liquor, 121 DEG C of sterilizings is made 20min.It will activate, the lactic acid bacteria tamed is enlarged culture and leavening is made is enlarged culture and leavening is made, press Leavening is inoculated into mixed liquor by 4wt% inoculum concentration to be fermented, 42 DEG C of fermentation 8h, obtains ginseng complex lactic acid fermented Liquid;In the mixed culture fermentation agent, the viable count of the lactic acid bacteria is 1 × 109CFU/g.Adjust the complex lactic acid fermented liquid of ginseng Debita spissitudo, is spray-dried, and EAT is 190 DEG C.Add and grind into the ginseng composite fermentation microcapsules gushed out Walnut 25g, Semen sesami nigrum 30g and flour 25g be nutrient powder finished product.
Experimental example 1
Anti-fatigue active:Forced swim test sets up Tiredness model.Operating method is:Daily 10:00AM~3:00PM, will Mouse, which is placed individually into, fills 23-25 DEG C, in the plastic cylinder (high 25cm, diameter 10cm) of high 10cm water.Every mouse quilt Compel the 6min in water, when murine terminator is struggled, keeping the state of floating, (or only small action is to keep head to expose water Face) it is considered as then fixed.Total testing time 6min, preceding 2min are the laundering period, and rear 4min records the fixed time.Often 30min is tested after its administration, continuous 15 days, the fixed time of manual double-blind study record mouse and swimming time.Often The water in container is changed in the swimming of mouse after terminating.Experimental animal is grouped:Male ICR mouse is grouped at random, every group 20.Point Not Wei physiological saline group (forced swimming gives physiological saline group simultaneously), to sample group (forced swimming simultaneously to embodiment 1~3 make Standby obtained ginseng composite fermentation nutrition powder capsule), control group.
The ginseng composite fermentation nutrient powder microcapsule preparation method be the same as Example 3 of control group fed, differing only in does not have Handle by fermentation.
It is 3g/kg/ days to sample group and control group dosage, 2 times a day, continues 15 days, carries out forced swimming within the 16th day Experiment, record mouse fixed time and swimming time.As a result show, ginseng composite fermentation nutrition powder capsule can be notable The fixed time of the tired mouse of reduction, there is significant difference compared with control group.Therefore, ginseng composite fermentation nutrient powder is micro- Capsule has effects that significantly to alleviate physical fatigue.
The fixed time statistical form of the mouse forced swimming test of table 1
Experimental example 2
Ginseng composite fermentation nutrition powder capsule of the present invention, can be under to the therapeutic effect of hot sign inferior health Stating clinical case observation is confirmed:
1st, patient profile:Selection meets the patient 100 of sub-health fatigue diagnostic criteria, wherein male 50, and women 50 Example, the course of disease is 3 months to 6 months, and age 40-60 Sui, average age 51.4 years old, sign shows as cold sign;It is all sick Per capita common disease is excluded through the generally conventional physical examination of doctor trained in Western medicine.
2nd, above-mentioned 100 patients are randomly divided into 5 groups, every group of 20 people.It is wherein without any processing to the 1st group of patient, the The ginseng composite fermentation nutrition powder capsule that 2-4 groups patient is prepared using embodiment 1-3, the 5th group of patient uses experimental example 1 Ginseng composite fermentation nutrition powder capsule prepared by control group, dose is 3 times a day, 1 every time, persistently to take 2 months, The data for taking drug compliance to be more than 90%.
3rd, after the course for the treatment of terminates, efficacy result is counted.Efficacy assessment standard the results are shown in Table 2 as shown in experimental example 1.
Therapeutic effect of the prescription Chinese medicine of table 2 to cold sign sub-health state
Although illustrate and describing the present invention with specific embodiment, but it will be appreciated that without departing substantially from the present invention's Many other changes and modification can be made in the case of spirit and scope.It is, therefore, intended that in the following claims Including belonging to all such changes and modifications in the scope of the invention.

Claims (10)

1. a kind of ginseng composite fermentation nutrient powder, it is characterised in that in parts by weight, is mainly prepared into by following material component Arrive:
10~20 parts of ginseng, 15~20 parts of coix seed, 20~30 parts of Chinese yam, 5~10 parts of jujube, 5~10 parts of matrimony vine, walnut 20~ 30 parts and 25~35 parts of Semen sesami nigrum.
2. ginseng composite fermentation nutrient powder according to claim 1, it is characterised in that in parts by weight, mainly by following Material component is prepared:
13~17 parts of ginseng, 16~19 parts of coix seed, 23~27 parts of Chinese yam, 6~9 parts of jujube, 6~9 parts of matrimony vine, walnut 23~27 28~32 parts of part and Semen sesami nigrum.
3. ginseng composite fermentation nutrient powder according to claim 1 or 2, it is characterised in that the material component also includes:
The parts by weight of milk powder 40~50;It is preferred that the milk powder is skimmed milk power.
4. ginseng composite fermentation nutrient powder according to claim 1 or 2, it is characterised in that the material component also includes:
The parts by weight of flour 20~30.
5. the preparation method of the ginseng composite fermentation nutrient powder described in any one of Claims 1 to 4, it is characterised in that including:
1) ginseng, coix seed, Chinese yam, jujube, matrimony vine are smashed mixing by, add water be heated to reflux extraction, by obtained leaching liquor with Sterilization treatment, which is carried out, after milk powder mixing obtains fermentation raw material;
2) is fermented lactobacillus inoculum into the fermentation raw material, obtained tunning is dried powder is made, Walnut, Semen sesami nigrum and flour is added into the powder to produce.
6. preparation method according to claim 5, it is characterised in that in step 1) in, the ginseng, coix seed, Chinese yam, Jujube, the gross mass of matrimony vine and the solid-to-liquid ratio of the water are 1:(8~12).
7. preparation method according to claim 6, it is characterised in that in step 1) in, it is described to be heated to reflux extraction specifically For:
Refluxing extraction 1.5h~2.5h under conditions of 55 DEG C~65 DEG C, extraction merges leaching liquor afterwards twice.
8. preparation method according to claim 5, it is characterised in that the lactic acid bacteria is inoculated with by 3~5wt% inoculum concentration Fermented into the fermentation raw material, 40 DEG C~44 DEG C fermentation 6h~10h;
Wherein, in the mixed culture fermentation agent, the viable count of the lactic acid bacteria is 1 × 108~10CFU/g。
9. preparation method according to claim 5, it is characterised in that in step 2) in, the drying is spray drying.
10. preparation method according to claim 9, it is characterised in that when carrying out the spray drying, EAT is 180 DEG C~200 DEG C.
CN201710559771.8A 2017-07-11 2017-07-11 ginseng composite fermentation nutrient powder and preparation method thereof Pending CN107279923A (en)

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Application publication date: 20171024