CN107261083A - A kind of Chinese medicine composition for treating allergic dermatitis - Google Patents
A kind of Chinese medicine composition for treating allergic dermatitis Download PDFInfo
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Abstract
The present invention discloses a kind of Chinese medicine composition for treating allergic dermatitis, is that the medicinal material matched by following weight is prepared from：5~15 parts of schizonepeta, 5~15 parts of perilla leaf, 5~15 parts of Chinese yam, 5~15 parts of rhizoma atractylodis macrocephalae, 5~15 parts of Radix Codonopsis, 5~15 parts of cassia twig, 5~15 parts of stir-baked RADIX PAEONIAE ALBA, 5~15 parts of jujube, windproof 4~8 parts, 4~8 parts of notopterygium root, 4~8 parts of the fruit of summer cypress, 4~8 parts of Fructus Aurantii, 4~8 parts of rascal, 4~8 parts of dried orange peel, 4~8 parts of rhizoma zingiberis, 4~8 parts of Chinese cassia tree, 4~8 parts of RADIX ACONITI LATERALIS PREPARATA, 4~8 parts of pinellia, 25~35 parts of radix scutellariae, 1~5 part of moxibustion radix glycyrrhizae.Prescription of the present invention has the work(of " warming kidney and strengthening spleen, harmonizing yingfen and weifen, dispelling wind and arresting itching ", with block antigen-antibody reaction, slow down or remove anaphylactoid anti-allergic effects and tissue repair effect, treatment cold-dampness in accumulate, type of by the wind becoming estranged facial anaphylaxis dermatitis has definite curative effect and good DEVELOPMENT PROSPECT.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for treating allergic dermatitis.
Background technology
Facial anaphylaxis dermatitis is that dept. of dermatology's clinic is common, multiple diseases, forehead, eye of the principal pathogenetic position for face
Eyelid, cheekbone, cheek etc., skin disorder also occurs in ears and scalp sometimes.Cardinal symptom is pruitus, and oedema differs in size
Bubble, or even sepage are rotten to the corn.Serious puzzlement not only is brought to the normal study and work of patient, such as treating not in time can also be because of patient
Scratch and secondary infection occur.
The incidence of disease of facial anaphylaxis dermatitis rises, with modern's daily life, life style etc. have it is certain associate,
Such as eating cold and uncooked food excessively, evening, which sleeps, stays up late.These can all injure the yang-energy of human splenocyte, kidney, cause raw in cold-dampness.Trembled with fear in some patientss body
Wet accumulate and turn to damp and hot, add diseases caused by external factors ailment said due to cold or exposure, body is had a cold damp and hot invasion.Or patient's ferritic is insufficiency of the spleen, to wind, it is cold,
Wet all heresies are susceptible.Damp and hot ailment said due to cold or exposure is caused a disease, and erythema, erythema occurs in skin of face, and itch is understood that；And cold-dampness ailment said due to cold or exposure causes
, then to be analyzed in terms of the negative imbalance of yin and yang of Basic Theories of Chinese Medicine：Cold damp being a kind of YIN pathogen blocks in interior, positive complemented lattice in table or
On, violate outside ailment said due to cold or exposure, be easy to top of hurting sb.'s feelings again, so as to the syndrome of true cold disease with false heat manifestation of face occur, face erythema or erythema is also occurred, with
And itch.Wind, cold, wet, all heresies of heat can all block human functional activity of vital energy, influence the metabolism of body aqueous, then face may occur in which oedema again
Or it is red and swollen, or even bubble, sepage erosion etc..
At present, using immunosupress or regulation therapy, antihistamine, amcinonide, calcium more than western medical treatment allergic dermatitis
Agent and loose after birth stabilizer etc..Including a variety of formulations such as oral, external application, injection, common first generation antihistamine chlorobenzene
Quick (chlorpheniramine), diphenhydramine, Sai Hai Lamines, cyproheptadine etc., second generation antihistamine astemizole (Astemizole), Te Feina
Determine, according to Bath fourth etc., hormone hydrocortisone, dexamethasone etc..Chemical drugs are effective rapid, can mitigate and control within a short period of time
Symptom processed.But it is used for a long time easily to be formed and relies on, adverse reaction is relatively more, recurrence rate after healing height, for a long time using head can be caused
Bitterly, the cardiovascular side effect such as the side effect of the central nervous system such as depression, dizziness, tired and cardiac arrhythmia, arrhythmia cordis.Separately
Outside, also diarrhoea, constipation, disorientation, diplopia, nosebleed, myalgia, insane and gynaecomastia, oligozoospermia,
The different side effect such as female irregular menstruation.Have not yet to see the Western medicine report that treatment anaphylaxis dermatosis effectively have no side effect again
Road.
With modern pharmacology and immunologic development, Chinese medicine resists allergic research more and more to be paid attention to, and finds many
Planting single and herbal mixture and its extract or effective ingredient has anti-allergic effects.
The content of the invention
The present invention proposes a kind of Chinese medicine composition for treating allergic dermatitis, has in terms of allergic dermatitis is treated definite
Curative effect and good development prospect.
The technical proposal of the invention is realized in this way：
A kind of Chinese medicine composition for treating allergic dermatitis, is that the medicinal material matched by following weight is prepared from：Schizonepeta 5~
15 parts, 5~15 parts of perilla leaf, 5~15 parts of Chinese yam, 5~15 parts of rhizoma atractylodis macrocephalae, 5~15 parts of Radix Codonopsis, 5~15 parts of cassia twig, stir-baked RADIX PAEONIAE ALBA 5~
15 parts, 5~15 parts of jujube, windproof 4~8 parts, it is 4~8 parts of notopterygium root, 4~8 parts of the fruit of summer cypress, 4~8 parts of Fructus Aurantii, 4~8 parts of rascal, old
4~8 parts of skin, 4~8 parts of rhizoma zingiberis, 4~8 parts of Chinese cassia tree, 4~8 parts of RADIX ACONITI LATERALIS PREPARATA, 4~8 parts of pinellia, 25~35 parts of radix scutellariae, moxibustion radix glycyrrhizae 1
~5 parts.
Wherein it is preferred to, a kind of Chinese medicine composition for treating allergic dermatitis is prepared by the medicinal material matched by following weight
Form：8~12 parts of schizonepeta, 8~12 parts of perilla leaf, 8~12 parts of Chinese yam, 8~12 parts of rhizoma atractylodis macrocephalae, 8~12 parts of Radix Codonopsis, cassia twig 8~12
Part, 8~12 parts of stir-baked RADIX PAEONIAE ALBA, 8~12 parts of jujube, windproof 5~7 parts, it is 5~7 parts of notopterygium root, 5~7 parts of the fruit of summer cypress, 5~7 parts of Fructus Aurantii, blue or green
5~7 parts of skin, 5~7 parts of dried orange peel, 5~7 parts of rhizoma zingiberis, 5~7 parts of Chinese cassia tree, 5~7 parts of RADIX ACONITI LATERALIS PREPARATA, 5~7 parts of pinellia, radix scutellariae 28~
32 parts, 2~4 parts of moxibustion radix glycyrrhizae.
Wherein it is preferred to, a kind of Chinese medicine composition for treating allergic dermatitis is prepared by the medicinal material matched by following weight
Form：10 parts of schizonepeta, 10 parts of perilla leaf, 10 parts of Chinese yam, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of Radix Codonopsis, 10 parts of cassia twig, 10 parts of stir-baked RADIX PAEONIAE ALBA, jujube
10 parts, windproof 6 parts, 6 parts of notopterygium root, 6 parts of the fruit of summer cypress, 6 parts of Fructus Aurantii, 6 parts of rascal, 6 parts of dried orange peel, 6 parts of rhizoma zingiberis, 6 parts of Chinese cassia tree, RADIX ACONITI LATERALIS PREPARATA
6 parts, 6 parts of pinellia, 30 parts of radix scutellariae, 3 parts of moxibustion radix glycyrrhizae.
Wherein, the nature and flavor of each medicinal material, channel tropism and effect are：
Schizonepeta：It is pungent；Slight bitter；Slightly warm in nature.Enter lung, Liver Channel.There is wind-dispelling, inducing diaphoresis, promoting eruption, hemostasis.
Perilla leaf：It is pungent, tepor, nontoxic；Enter the spleen channel, the warp of lung channel two；There is expelling cold and relieving exterior syndrome, regulating the flow of QI to ease the stomach.
Chinese yam：It is sweet, put down；Returns spleen, lung, kidney channel；With tonifying spleen nourishing the stomach, engender liquid and benefic lung, the effect of kidney tonifying is puckery smart.
Rhizoma atractylodis macrocephalae：Bitter, sweet, temperature.Returns spleen, stomach have strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, antiabortive effect.
Radix Codonopsis：It is sweet, put down.With tonifying middle-Jiao and Qi, clearing heat and detoxicating, the effect of expelling phlegm and arresting coughing.
Cassia twig：It is pungent, sweet, temperature；Enter the heart, lung, bladder warp；The effect of with complement sun, promoting blood circulation, warming spleen and stomach.
Stir-baked RADIX PAEONIAE ALBA：Bitter, acid, are slightly cold；Return liver, the spleen channel；There are smooth liver and relieve pain, nourishing blood for regulating menstruation, effect of astringing YIN to stop sweating.
Jujube：It is sweet, temperature.Returns spleen, stomach.With tonifying middle-Jiao and Qi, nourishing blood and tranquilization, the effect of relaxing the property of medicine.
It is windproof：It is pungent, sweet, slightly warm in nature.Return bladder, liver, the spleen channel.With expelling pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, the work(that only convulsion is jerked surely
Effect.
Notopterygium root：Nature and flavor are pungent, hardship, temperature.Return bladder, kidney channel；With cold dispelling, wind-dispelling, dehumidifying, the effect of analgesic.
The fruit of summer cypress：Sweet-bitter flavor, trembles with fear；Enter kidney channel, bladder warp；With diuresis, effect of clearing away damp-heat.
Fructus Aurantii：Bitter；Acid；Cold nature channel tropism:Lung；Spleen；Liver；Stomach；Large intestine channel；Work(with regulating the flow of QI to ease the stomach, the stagnant dissipate-swelling of row
Effect.
Rascal：It is bitter, pungent, it is warm-natured.Return liver, courage, stomach.There are soothing the liver relieving stagnant Qi, the stagnant effect of disperse accumulationsization.
Dried orange peel：It is bitter, pungent, it is warm-natured.Return lung, the spleen channel.There is regulating qi-flowing for strengthening spleen, the effect of eliminating dampness and eliminating phlegm.
Rhizoma zingiberis：It is pungent, property heat.Returns spleen, stomach, kidney, the heart, lung channel.With warming spleen and stomach for dispelling cold, Back to Yang Tongmai, the work(of Wenfei of drink
Effect.
Chinese cassia tree：Property heat, it is pungent, sweet；Enter kidney channel, the spleen channel, the heart channel of Hang-Shaoyin, Liver Channel；With warming spleen and stomach for dispelling cold, stomach invigorating of invigorating blood circulation, analgesic
The effect of.
RADIX ACONITI LATERALIS PREPARATA：Extremely hot in nature, it is pungent, sweet, it is poisonous；Enter the heart channel of Hang-Shaoyin, kidney channel, the spleen channel；With recuperating depleted yang, mends fire supporing yang,
The effect of eliminating cold to stop pain.
Pinellia：Pungent, temperature；It is poisonous.Returns spleen, stomach, lung channel；Has effect of stopping nausea and vomiting by lowering the adverse flow of QI.
Radix scutellariae：It is bitter, cold in nature, have heat-clearing and damp-drying drug, purging intense heat and detonicating, hemostasis, it is antiabortive the effects such as.
Moxibustion radix glycyrrhizae：It is sweet, put down.The thoughts of returning home, spleen, lung, stomach.With tonifying spleen and stomach, the effect of Yiqi and vein recovery.
Full side of the invention is sweet with rhizoma atractylodis macrocephalae, Radix Codonopsis, cassia twig, dried orange peel, Chinese cassia tree, moxibustion using Chinese yam, notopterygium root, RADIX ACONITI LATERALIS PREPARATA as monarch drug in a prescription
Grass is ministerial drug, with perilla leaf, stir-baked RADIX PAEONIAE ALBA, jujube, Fructus Aurantii, rascal, rhizoma zingiberis, pinellia, baikal skullcap root be used as the adjuvant medicine, with schizonepeta, windproof to make
Medicine, the effect of " warming kidney and strengthening spleen, harmonizing yingfen and weifen, dispelling wind and arresting itching " is played altogether.
Beneficial effects of the present invention：
Complete square totally 20 taste Chinese medicine of the invention, by experimental verifications such as the pharmacodynamics tests of preclinical observation and full side,
The party truly has the work(of " warming kidney and strengthening spleen, harmonizing yingfen and weifen, dispelling wind and arresting itching ", with blocking antigen-antibody reaction, slow down or remove allergy
Anti-allergic effects and the tissue repair effect of reaction, accumulate, type of by the wind becoming estranged facial anaphylaxis dermatitis has really in treatment cold-dampness
The curative effect and good DEVELOPMENT PROSPECT cut.Also, compared with the Western medicine for the treatment of allergic dermatitis, Small side effects.
Embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based in the present invention
Embodiment, all other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all
Belong to the scope of protection of the invention.
Embodiment 1
A kind of Chinese medicine composition for treating allergic dermatitis, is that the medicinal material matched by following weight is prepared from：Schizonepeta 10
Part, 10 parts of perilla leaf, 10 parts of Chinese yam, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of Radix Codonopsis, 10 parts of cassia twig, 10 parts of stir-baked RADIX PAEONIAE ALBA, 10 parts of jujube, windproof 6
Part, 6 parts of notopterygium root, 6 parts of the fruit of summer cypress, 6 parts of Fructus Aurantii, 6 parts of rascal, 6 parts of dried orange peel, 6 parts of rhizoma zingiberis, 6 parts of Chinese cassia tree, 6 parts of RADIX ACONITI LATERALIS PREPARATA, pinellia
6 parts, 30 parts of radix scutellariae, 3 parts of moxibustion radix glycyrrhizae.
Embodiment 2
A kind of Chinese medicine composition for treating allergic dermatitis, is that the medicinal material matched by following weight is prepared from：Schizonepeta 5
Part, 15 parts of perilla leaf, 5 parts of Chinese yam, 15 parts of rhizoma atractylodis macrocephalae, 5 parts of Radix Codonopsis, 15 parts of cassia twig, 5 parts of stir-baked RADIX PAEONIAE ALBA, 15 parts of jujube, windproof 4 parts, Qiang
8 parts living, 4 parts of the fruit of summer cypress, 8 parts of Fructus Aurantii, 4 parts of rascal, 8 parts of dried orange peel, 4 parts of rhizoma zingiberis, 8 parts of Chinese cassia tree, 4 parts of RADIX ACONITI LATERALIS PREPARATA, 8 parts of pinellia,
25 parts of radix scutellariae, 5 parts of moxibustion radix glycyrrhizae.
Embodiment 3
A kind of Chinese medicine composition for treating allergic dermatitis, is that the medicinal material matched by following weight is prepared from：Schizonepeta 15
Part, 5 parts of perilla leaf, 15 parts of Chinese yam, 5 parts of rhizoma atractylodis macrocephalae, 15 parts of Radix Codonopsis, 5 parts of cassia twig, 15 parts of stir-baked RADIX PAEONIAE ALBA, 5 parts of jujube, windproof 8 parts, Qiang
4 parts living, 8 parts of the fruit of summer cypress, 4 parts of Fructus Aurantii, 8 parts of rascal, 4 parts of dried orange peel, 8 parts of rhizoma zingiberis, 4 parts of Chinese cassia tree, 8 parts of RADIX ACONITI LATERALIS PREPARATA, 4 parts of pinellia,
35 parts of radix scutellariae, 1 part of moxibustion radix glycyrrhizae.
Embodiment 4
A kind of Chinese medicine composition for treating allergic dermatitis, is that the medicinal material matched by following weight is prepared from：
8 parts of schizonepeta, 12 parts of perilla leaf, 8 parts of Chinese yam, 12 parts of rhizoma atractylodis macrocephalae, 8 parts of Radix Codonopsis, 12 parts of cassia twig, 8 parts of stir-baked RADIX PAEONIAE ALBA, jujube 12
Part, windproof 5 parts, 7 parts of notopterygium root, 5 parts of the fruit of summer cypress, 7 parts of Fructus Aurantii, 5 parts of rascal, 7 parts of dried orange peel, 5 parts of rhizoma zingiberis, 7 parts of Chinese cassia tree, RADIX ACONITI LATERALIS PREPARATA 5
Part, 7 parts of pinellia, 28 parts of radix scutellariae, 4 parts of moxibustion radix glycyrrhizae.
Embodiment 5
A kind of Chinese medicine composition for treating allergic dermatitis, is that the medicinal material matched by following weight is prepared from：Schizonepeta 12
Part, 8 parts of perilla leaf, 12 parts of Chinese yam, 8 parts of rhizoma atractylodis macrocephalae, 12 parts of Radix Codonopsis, 8 parts of cassia twig, 12 parts of stir-baked RADIX PAEONIAE ALBA, 8 parts of jujube, windproof 7 parts, Qiang
5 parts living, 7 parts of the fruit of summer cypress, 5 parts of Fructus Aurantii, 7 parts of rascal, 5 parts of dried orange peel, 7 parts of rhizoma zingiberis, 5 parts of Chinese cassia tree, 7 parts of RADIX ACONITI LATERALIS PREPARATA, 5 parts of pinellia,
32 parts of radix scutellariae, 2 parts of moxibustion radix glycyrrhizae.
Application Example
The beneficial effects of the present invention will now be described with reference to clinical experimental data：
1st, general information
Inventor's in July, 2014 is to the out-patient for collecting 240 allergic dermatitises between in November, 2016 altogether.Above-mentioned outpatient service
Patient is to accumulate in cold-dampness, type of by the wind becoming estranged facial anaphylaxis dermatitis：The light red spot of face, micro- swollen, itch or face include Dual-eyelid
Water kind, erythema, itch, indigestion and loss of appetite, loose stool, greasy, tongue side print with teeth that tongue nature is light red, tongue is got sun in vain.
It is randomly divided into：Experimental group 200, control group 40.Situations such as to the age of two groups of patients, the state of an illness, the course of disease, is carried out
It is compared, statistical procedures, no significant difference, two groups of cases have comparativity.
2nd, test method
2.1 treatment method
Control group：Oral chlorpheniramine maleate tabletses, take according to its specification.The course for the treatment of 2 weeks.
Experimental group：The Chinese medicine one portion per day of embodiment 1~5, decocting twice, warmly takes.
2.2 observation item：To red swelling of the skin before and after treatment, itch, wheal, the symptom such as decortication are observed.
3rd, criterion of therapeutical effect and treatment results
3.1 criterion of therapeutical effect
Recovery from illness：Clinical symptoms all disappear, and one week no relapse of withdrawal observation.It is effective：Clinical symptoms substantially mitigate.
Effectively：Clinical symptom relief.It is invalid：No significant improvement or aggravated in clinical symptoms.
3.2 treatment statistics are shown in Table 1.
1 two groups of comparitive studies of table
From data above, treatment group's facial anaphylaxis dermatitis patients, treated effect is 97.5%, control group face
Allergic dermatitis patient treated effect is 90%, and treatment group's therapeutic effect is to be substantially better than control group, and treatment group's cure rate
Apparently higher than control group.And observation is tracked to two groups of recurrence rate, the recurrence rate for the treatment of group is only 5%, and control group is answered
Hair rate is 20%, and the recurrence rate for the treatment of group is significantly lower than control group.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
God is with principle, and any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.
Claims (3)
1. a kind of Chinese medicine composition for treating allergic dermatitis, it is characterised in that be the medicinal material matched by following weight prepare and
Into：5~15 parts of schizonepeta, 5~15 parts of perilla leaf, 5~15 parts of Chinese yam, 5~15 parts of rhizoma atractylodis macrocephalae, 5~15 parts of Radix Codonopsis, 5~15 parts of cassia twig,
5~15 parts of stir-baked RADIX PAEONIAE ALBA, 5~15 parts of jujube, windproof 4~8 parts, 4~8 parts of notopterygium root, 4~8 parts of the fruit of summer cypress, 4~8 parts of Fructus Aurantii, rascal 4
~8 parts, 4~8 parts of dried orange peel, 4~8 parts of rhizoma zingiberis, 4~8 parts of Chinese cassia tree, 4~8 parts of RADIX ACONITI LATERALIS PREPARATA, 4~8 parts of pinellia, radix scutellariae 25~35
Part, 1~5 part of moxibustion radix glycyrrhizae.
2. a kind of Chinese medicine composition for treating allergic dermatitis according to claim 1, it is characterised in that be by following heavy
The medicinal material of amount proportioning is prepared from：8~12 parts of schizonepeta, 8~12 parts of perilla leaf, 8~12 parts of Chinese yam, 8~12 parts of rhizoma atractylodis macrocephalae, Radix Codonopsis 8
~12 parts, 8~12 parts of cassia twig, 8~12 parts of stir-baked RADIX PAEONIAE ALBA, 8~12 parts of jujube, windproof 5~7 parts, 5~7 parts of notopterygium root, the fruit of summer cypress 5~7
Part, 5~7 parts of Fructus Aurantii, 5~7 parts of rascal, 5~7 parts of dried orange peel, 5~7 parts of rhizoma zingiberis, 5~7 parts of Chinese cassia tree, 5~7 parts of RADIX ACONITI LATERALIS PREPARATA, pinellia
5~7 parts, 28~32 parts of radix scutellariae, 2~4 parts of moxibustion radix glycyrrhizae.
3. a kind of Chinese medicine composition for treating allergic dermatitis according to claim 1, it is characterised in that be by following heavy
The medicinal material of amount proportioning is prepared from：10 parts of schizonepeta, 10 parts of perilla leaf, 10 parts of Chinese yam, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of Radix Codonopsis, 10 parts of cassia twig,
10 parts of stir-baked RADIX PAEONIAE ALBA, 10 parts of jujube, windproof 6 parts, 6 parts of notopterygium root, 6 parts of the fruit of summer cypress, 6 parts of Fructus Aurantii, 6 parts of rascal, 6 parts of dried orange peel, rhizoma zingiberis 6
Part, 6 parts of Chinese cassia tree, 6 parts of RADIX ACONITI LATERALIS PREPARATA, 6 parts of pinellia, 30 parts of radix scutellariae, 3 parts of moxibustion radix glycyrrhizae.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582799A (en) * | 2017-10-27 | 2018-01-16 | 成都中医药大学附属医院 | A kind of pharmaceutical composition for treating atopic dermatitis and its production and use |
| CN109602878A (en) * | 2019-01-24 | 2019-04-12 | 桂林理工大学 | A kind of ointment antipruritic for skin degerming and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895558A (en) * | 2012-10-25 | 2013-01-30 | 辛晓林 | Chinese medicine for treating allergic dermatitis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895558A (en) * | 2012-10-25 | 2013-01-30 | 辛晓林 | Chinese medicine for treating allergic dermatitis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582799A (en) * | 2017-10-27 | 2018-01-16 | 成都中医药大学附属医院 | A kind of pharmaceutical composition for treating atopic dermatitis and its production and use |
| CN109602878A (en) * | 2019-01-24 | 2019-04-12 | 桂林理工大学 | A kind of ointment antipruritic for skin degerming and preparation method thereof |
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