CN107261026A - 一种防治风湿筋骨痛的药酒及其制备方法 - Google Patents
一种防治风湿筋骨痛的药酒及其制备方法 Download PDFInfo
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- CN107261026A CN107261026A CN201710643178.1A CN201710643178A CN107261026A CN 107261026 A CN107261026 A CN 107261026A CN 201710643178 A CN201710643178 A CN 201710643178A CN 107261026 A CN107261026 A CN 107261026A
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Abstract
本发明提供了一种中药组合物,组分包括糯米藤、青筋藤、牛膝、五指桃、马樱丹、田七、千斤拔、樟树根、鸡血藤、赤芍、当归、红花、丹参、续断、寄生、地龙、薏米、锁阳、鹿角霜、补骨脂、骨碎补、牛膝、松节、独活、川芎、威灵仙、牛大力、巴戟天、乌鞘蛇、细辛、防风、白术、乳香、没药、炮山甲、桂枝、黄芪、杜仲、岗稔根、蜈蚣、山苍根、鹰不泊、茨实、葛根、以及全蝎。本发明还提供了采用该中药组合物制备的药酒、中药制剂及其制备方法和应用。本发明对风湿、内风湿型关节炎、腰腿疼、骨质增生、肩周炎、骨折、跌打损伤、软组织损伤及各种筋骨疼痛等病症,具有良好治愈效果,在临床中有效率可达到95%。
Description
技术领域
本发明涉及中药领域,具体涉及一种防治风湿筋骨痛的中药组合物、药酒、中药制剂及其制备方法和应用。
背景技术
风湿、类风湿性关节炎是当前世界医学科学上的难题,医学上称为不死的癌症。据不完全统计,世界上有三分之一以上的人口患有各种风湿性疾病,其中有80%的转为慢性疾病。类风湿性关节炎就如感冒发烧一样普遍,重点是山地沿海地区和高寒地区,长期以来一直困扰着人们的生产和生活,给广大患者带来极大的痛苦,轻者造成患者阴雨天气、寒冷季节的关节疼痛、运动失灵,重者造成终生残废,生活不能自理。不少人因之产生其它并发症,危及生命。风湿、类风湿性关节炎发病原因主要是由正气不足,感受风、寒、湿、热之邪,闭阻经络,气血运行不畅所致。正如《类证制裁-痹症》所云:“诸痹……良由营卫先虚,腠理不密,风寒湿乘虚内袭。正气为邪所阻,不能宣行,因而留滞,气血凝涩,久而成痹”。目前,全球范围内还没有根治风湿性关节炎的特效药。而现在治疗风湿性关节炎、骨质增生、腰腿颈椎病症的药物大部分具有副作用,对皮肤具有刺激作用,停药后容易复发,且价格较贵,治疗效果不理想且不能根治。
发明内容
本发明的目的在于克服现有技术的不足,提供一种更为有效防治风湿筋骨痛的中药组合物,治愈率高且疗效显著。本发明还提供了采用该中药组合物制备的药酒及其制备方法和应用。
本发明的第一个方面是提供一种中药组合物,按照重量份数计,其组分包括:糯米藤80-120份、青筋藤80-120份、牛膝10-50份、五指桃80-120份、马樱丹80-120份、田七30-70份、千斤拔80-120份、樟树根10-50份、鸡血藤80-120份、赤芍80-120份、当归80-120份、红花30-70份、丹参80-120份、续断80-120份、桑寄生40-80份、地龙30-70份、薏米80-120份、锁阳30-70份、鹿角霜30-70份、补骨脂40-80份、骨碎补40-80份、牛膝40-80份、松节40-80份、独活40-80份、川芎40-80份、威灵仙80-120份、牛大力80-120份、巴戟天30-70份、乌鞘蛇30-70份、细辛10-50份、防风40-80份、白术40-80份、乳香30-70份、没药30-70份、炮山甲30-70份、桂枝60-100份、黄芪80-120份、杜仲40-80份、岗稔根80-120份、蜈蚣20-60份、山苍根20-60份、鹰不泊40-80份、茨实40-80份、葛根40-80份、以及全蝎10-50份。
优选地,按照重量份数计,所述中药组合物的组分包括:糯米藤90-110份、青筋藤90-110份、牛膝20-40份、五指桃90-110份、马樱丹90-110份、田七40-60份、千斤拔90-110份、樟树根20-40份、鸡血藤90-110份、赤芍90-110份、当归90-110份、红花40-60份、丹参90-110份、续断90-110份、桑寄生50-70份、地龙40-60份、薏米90-110份、锁阳40-60份、鹿角霜40-60份、补骨脂50-70份、骨碎补50-70份、牛膝50-70份、松节50-70份、独活50-70份、川芎50-70份、威灵仙90-110份、牛大力90-110份、巴戟天40-60份、乌鞘蛇40-60份、细辛20-40份、防风50-70份、白术50-70份、乳香40-60份、没药40-60份、炮山甲40-60份、桂枝70-90份、黄芪90-110份、杜仲50-70份、岗稔根90-110份、蜈蚣30-50份、山苍根30-50份、鹰不泊50-70份、茨实50-70份、葛根50-70份、以及全蝎20-40份。
进一步优选地,按照重量份数计,所述中药组合物的组分包括:糯米藤100份、青筋藤100份、牛膝30份、五指桃100份、马樱丹100份、田七50份、千斤拔100份、樟树根30份、鸡血藤100份、赤芍100份、当归100份、红花50份、丹参100份、续断100份、桑寄生60份、地龙50份、薏米100份、锁阳50份、鹿角霜50份、补骨脂60份、骨碎补60份、牛膝60份、松节60份、独活60份、川芎60份、威灵仙100份、牛大力100份、巴戟天50份、乌鞘蛇50份、细辛30份、防风60份、白术60份、乳香50份、没药50份、炮山甲50份、桂枝80份、黄芪100份、杜仲60份、岗稔根100份、蜈蚣40份、山苍根40份、鹰不泊60份、茨实60份、葛根60份、以及全蝎30份。
本发明的第二个方面是提供一种防治风湿筋骨痛的药酒,由酒浸泡本发明第一个方面所述的中药组合物制备而成。该药酒可内服或外擦,无副作用。
其中,对于酒的用量本发明没有特别的限定,本领域技术人员可以采用药酒的常用配比进行配置,在一个优选的实施方式中,酒与中药组合物的重量比为:50000-500︰300g。
本发明的第三个方面是提供一种本发明第二个方面所述的药酒的制备方法,取中药组合物,加入酒浸泡,即得。
其中,对于浸泡时间本发明没有特别的限定,本领域技术人员可以根据以往经验酌情处理。在一个优选的实施方式中,浸泡至少15天。
本发明的第四个方面是提供一种防治防治风湿筋骨痛的中药制剂,其活性成分为本发明第一个方面所述的中药组合物。
本发明的第五个方面是提供本发明第四个方面所述的中药制剂的制备方法,将本发明第一个方面所述的中药组合物粉碎、过筛,制成制剂。
本发明的第六个方面是提供如本发明第一个方面项所述的中药组合物、本发明第二个方面所述的药酒、或者本发明第四个方面所述的中药制剂在制备防治风湿筋骨痛的药物或保健品中的应用。
本发明具有活血、通络、祛伤止痛、舒经解痉、抗风湿、滋补肝肾、健脾除湿等作用。对风湿、内风湿型关节炎、腰腿疼、骨质增生、肩周炎、骨折、跌打损伤、软组织损伤及各种筋骨疼痛等病症,具有良好的治愈效果,在临床中总有效率达到95%。
具体实施方式
下面结合具体的实施方式对本发明作进一步的说明,以更好地理解本发明。
实施例1
取糯米藤100g、青筋藤100g、牛膝30g、五指桃100g、马樱丹100g、田七50g、千斤拔100g、樟树根30g、鸡血藤100g、赤芍100g、当归100g、红花50g、丹参100g、续断100g、桑寄生60g、地龙50g、薏米100g、锁阳50g、鹿角霜50g、补骨脂60g、骨碎补60g、牛膝60g、松节60g、独活60g、川芎60g、威灵仙100g、牛大力100g、巴戟天50g、乌鞘蛇50g、细辛30g、防风60g、白术60g、乳香50g、没药50g、炮山甲50g、桂枝80g、黄芪100g、杜仲60g、岗稔根100g、蜈蚣40g、山苍根40g、鹰不泊60g、茨实60g、葛根60g、以及全蝎30g,装入干净瓶子中,加入白酒50kg,加盖密封,置阴凉干燥处,常摇动几次,经15日-1个月后即可。
风湿筋骨痛患者100例,男性50例,女性50例。取实施例1制得的药酒每日口服3次,每次5-15毫升,温饮,并视情况外涂患处,30天为一个疗程。痊愈71例,显效24例,无效5例,总有效率为95%。疗效标准为:痊愈:症状、体征完全消失,步行及摇摆改善,风湿因子阴性;显效:症状、体征明显好转,晨僵、步态及摇摆改善,风湿因子阴性;无效:症状、体征无改善,风湿因子无改善(下同)。
实施例2
取糯米藤110g、青筋藤90g、牛膝40g、五指桃90g、马樱丹110g、田七40g、千斤拔110g、樟树根20g、鸡血藤110g、赤芍90g、当归110g、红花40g、丹参110g、续断90g、桑寄生70g、地龙40g、薏米110g、锁阳40g、鹿角霜60g、补骨脂50g、骨碎补70g、牛膝50g、松节70g、独活50g、川芎70g、威灵仙90g、牛大力110g、巴戟天40g、乌鞘蛇60g、细辛20g、防风70g、白术50g、乳香60g、没药40g、炮山甲60g、桂枝70g、黄芪110g、杜仲70g、岗稔根90g、蜈蚣50g、山苍根30g、鹰不泊70g、茨实50g、葛根70g、以及全蝎20g,装入干净瓶子中,加入白酒50kg,加盖密封,置阴凉干燥处,常摇动几次,经15日-1个月后即可。
风湿筋骨痛患者100例,男性50例,女性50例。取实施例2制得的药酒每日口服3次,每次5-15毫升,温饮,并视情况外涂患处,30天为一个疗程。痊愈69例,显效28例,无效3例,总有效率为97%。
实施例3
取糯米藤90g、青筋藤110g、牛膝20g、五指桃110g、马樱丹90g、田七60g、千斤拔90g、樟树根40g、鸡血藤90g、赤芍110g、当归90g、红花60g、丹参90g、续断110g、桑寄生50g、地龙60g、薏米90g、锁阳60g、鹿角霜40g、补骨脂70g、骨碎补50g、牛膝70g、松节50g、独活70g、川芎50g、威灵仙110g、牛大力90g、巴戟天60g、乌鞘蛇40g、细辛40g、防风50g、白术70g、乳香40g、没药60g、炮山甲40g、桂枝90g、黄芪90g、杜仲50g、岗稔根110g、蜈蚣30g、山苍根50g、鹰不泊50g、茨实70g、葛根50g、以及全蝎40g,装入干净瓶子中,加入白酒50kg,加盖密封,置阴凉干燥处,常摇动几次,经15日-1个月后即可。
风湿筋骨痛患者100例,男性50例,女性50例。取实施例3制得的药酒每日口服3次,每次5-15毫升,温饮,并视情况外涂患处,30天为一个疗程。痊愈68例,显效27例,无效5例,总有效率为95%。
实施例4
取糯米藤120g、青筋藤120g、牛膝50g、五指桃120g、马樱丹120g、田七30g、千斤拔80g、樟树根10g、鸡血藤80g、赤芍80g、当归80g、红花30g、丹参120g、续断120g、桑寄生80g、地龙70g、薏米120g、锁阳70g、鹿角霜30g、补骨脂40g、骨碎补40g、牛膝40g、松节40g、独活40g、川芎40g、威灵仙120g、牛大力120g、巴戟天70g、乌鞘蛇70g、细辛50g、防风80g、白术40g、乳香30g、没药30g、炮山甲30g、桂枝60g、黄芪80g、杜仲40g、岗稔根120g、蜈蚣60g、山苍根60g、鹰不泊80g、茨实80g、葛根80g、以及全蝎10g,装入干净瓶子中,加入白酒50kg,加盖密封,置阴凉干燥处,常摇动几次,经15日-1个月后即可。
风湿筋骨痛患者100例,男性50例,女性50例。取实施例4制得的药酒每日口服3次,每次5-15毫升,温饮,并视情况外涂患处,30天为一个疗程。痊愈62例,显效34例,无效4例,总有效率为96%。
实施例5
取糯米藤80g、青筋藤80g、牛膝10g、五指桃80g、马樱丹80g、田七70g、千斤拔120g、樟树根50g、鸡血藤120g、赤芍120g、当归120g、红花70g、丹参80g、续断80g、桑寄生40g、地龙30g、薏米80g、锁阳30g、鹿角霜70g、补骨脂80g、骨碎补80g、牛膝80g、松节80g、独活80g、川芎80g、威灵仙80g、牛大力80g、巴戟天30g、乌鞘蛇30g、细辛10g、防风40g、白术80g、乳香70g、没药70g、炮山甲70g、桂枝100g、黄芪120g、杜仲80g、岗稔根80g、蜈蚣20g、山苍根20g、鹰不泊40g、茨实40g、葛根40g、以及全蝎50g,装入干净瓶子中,加入白酒50kg,加盖密封,置阴凉干燥处,常摇动几次,经15日-1个月后即可。
风湿筋骨痛患者100例,男性50例,女性50例。取实施例5制得的药酒每日口服3次,每次5-15毫升,温饮,并视情况外涂患处,30天为一个疗程。痊愈63例,显效32例,无效5例,总有效率为95%。
实施例6-8
实施例6-8的药材用量分别与实施例1-3的相同,不同之处在于制备工艺不同,将药材粉碎、过筛,制成胶囊(应当理解的是,也可以制成其他常用的口服固定制剂,例如片剂、粉剂等,也可以制成其他的外敷制剂,例如膏药等)。临床治疗效果分别同实施例1-3。
实施例9-10
实施例9-10的药材用量分别与实施例4-5的相同,不同之处在于制备工艺不同,将药材粉碎、过筛,制成膏药。临床治疗效果分别同实施例4-5。
临床案例列举:
(1)蔡某某,男,55岁,反复性关节肿痛5年余,阴雨天加重,经多方治疗,效果不佳。后服用本发明药酒,服用半个月后,症状减轻,服用一个月后,症状基本消失,继续服用一个月,随访至今,未见复发。
(2)王某某,男,55岁,工作不小心从3米高空跌伤,头、颈、背、腰部经常疼痛,阴雨天加重,不能工作5年,经大小医院治疗多年无效,后服用本发明药酒,3个月痊愈,未见复发。
(3)王某某,女,48岁,患风湿关节炎伴多发性神经痛多年,行动不便,腰背胀痛,弯腰苦难,四肢经常抽筋,经多方治疗无果,后服用本发明药酒,1个月症状减轻,3个月痊愈。
(4)陈某某,女,35岁,因生小孩月内淋雨感冒发热后引起全是骨关节肿痛,反反复复疼痛多年,痛苦难忍,行走困难,经多方治疗效果不佳,后服用本发明药酒,2个月症状消失。
以上对本发明的具体实施例进行了详细描述,但其只是作为范例,本发明并不限制于以上描述的具体实施例。对于本领域技术人员而言,任何对本发明进行的等同修改和替代也都在本发明的范畴之中。因此,在不脱离本发明的精神和范围下所作的均等变换和修改,都应涵盖在本发明的范围内。
Claims (10)
1.一种中药组合物,其特征在于,按照重量份数计,其组分包括:糯米藤80-120份、青筋藤80-120份、牛膝10-50份、五指桃80-120份、马樱丹80-120份、田七30-70份、千斤拔80-120份、樟树根10-50份、鸡血藤80-120份、赤芍80-120份、当归80-120份、红花30-70份、丹参80-120份、续断80-120份、寄生40-80份、地龙30-70份、薏米80-120份、锁阳30-70份、鹿角霜30-70份、补骨脂40-80份、骨碎补40-80份、牛膝40-80份、松节40-80份、独活40-80份、川芎40-80份、威灵仙80-120份、牛大力80-120份、巴戟天30-70份、乌鞘蛇30-70份、细辛10-50份、防风40-80份、白术40-80份、乳香30-70份、没药30-70份、炮山甲30-70份、桂枝60-100份、黄芪80-120份、杜仲40-80份、岗稔根80-120份、蜈蚣20-60份、山苍根20-60份、鹰不泊40-80份、茨实40-80份、葛根40-80份、以及全蝎10-50份。
2.根据权利要求1所述的中药组合物,其特征在于,按照重量份数计,糯米藤90-110份、青筋藤90-110份、牛膝20-40份、五指桃90-110份、马樱丹90-110份、田七40-60份、千斤拔90-110份、樟树根20-40份、鸡血藤90-110份、赤芍90-110份、当归90-110份、红花40-60份、丹参90-110份、续断90-110份、寄生50-70份、地龙40-60份、薏米90-110份、锁阳40-60份、鹿角霜40-60份、补骨脂50-70份、骨碎补50-70份、牛膝50-70份、松节50-70份、独活50-70份、川芎50-70份、威灵仙90-110份、牛大力90-110份、巴戟天40-60份、乌鞘蛇40-60份、细辛20-40份、防风50-70份、白术50-70份、乳香40-60份、没药40-60份、炮山甲40-60份、桂枝70-90份、黄芪90-110份、杜仲50-70份、岗稔根90-110份、蜈蚣30-50份、山苍根30-50份、鹰不泊50-70份、茨实50-70份、葛根50-70份、以及全蝎20-40份。
3.根据权利要求2所述的中药组合物,其特征在于,按照重量份数计,其组分包括:糯米藤100份、青筋藤100份、牛膝30份、五指桃100份、马樱丹100份、田七50份、千斤拔100份、樟树根30份、鸡血藤100份、赤芍100份、当归100份、红花50份、丹参100份、续断100份、寄生60份、地龙50份、薏米100份、锁阳50份、鹿角霜50份、补骨脂60份、骨碎补60份、牛膝60份、松节60份、独活60份、川芎60份、威灵仙100份、牛大力100份、巴戟天50份、乌鞘蛇50份、细辛30份、防风60份、白术60份、乳香50份、没药50份、炮山甲50份、桂枝80份、黄芪100份、杜仲60份、岗稔根100份、蜈蚣40份、山苍根40份、鹰不泊60份、茨实60份、葛根60份、以及全蝎30份。
4.一种防治风湿筋骨痛的药酒,其特征在于,由酒浸泡权利要求1-3中任意一项所述的中药组合物制备而成。
5.根据权利要求4所述的药酒,其特征在于,酒与中药组合物的质量为:50000-500︰300g。
6.一种如权利要求4或5所述的药酒的制备方法,其特征在于,取中药组合物,加入酒浸泡,即得。
7.根据权利要求6所述的制备方法,其特征在于,浸泡至少15天。
8.一种防治防治风湿筋骨痛的中药制剂,其特征在于,其活性成分为权利要求1-3中任意一项所述的中药组合物。
9.一种如权利要求8所述的中药制剂的制备方法,其特征在于,将权利要求1-3中任意一项所述的中药组合物粉碎、过筛,制成制剂。
10.如权利要求1-3中任意一项所述的中药组合物、权利要求4或5所述的药酒、或者权利要求8所述的中药制剂在制备防治风湿筋骨痛的药物或保健品中的应用。
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