CN107260572A - A kind of antibacterial fish scale protein facial mask and preparation method thereof - Google Patents
A kind of antibacterial fish scale protein facial mask and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to biological technical field, it is related to a kind of antibacterial fish scale protein facial mask and preparation method thereof, the antibacterial fish scale protein facial mask includes following material：Fish scale protein peptide, sodium hyaluronate, plant extraction liquid, Nano silver grain, glycerine, pyrrolidone sodium carboxylate, xanthans, film forming agent, deionized water；The present invention is with fish scale and raw material, and fish scale is biological material, harmless to the human body, can be degradable, environmentally safe, also achieves the recycling of waste；The present invention assigns the effect of facial mask antibacterial bacteriostatic by adding Nano silver grain in facial mask, and to any side effect of human body thing, it is safe.
Description
Technical field
The present invention relates to biological technical field, more particularly to a kind of antibacterial fish scale protein facial mask and preparation method thereof.
Background technology
Collagen is protein component main in skin histology, the 70%~80% of skin dry weight is accounted for, in corium
Fibrocyte (Fibroblasts) manufacture, collagen is a kind of white, transparent, branchiess fibrillation, is a kind of in itself
Very firm protein, in youth, health, few by the skin of sun damages, it constitutes the slightly curved fiber of a branch of beam, mutually
With last layer and next layer of formation right-angle array, this makes skin obtain solid effect.But when the years increase, collagen is not
But quantity reduce, and arrangement also become irregular, corium thus it is thinning；Environmental factor is easier to make collagen dissolving disappear
Lose.Cause the aging of skin.Exactly because the loss of collagen causes the collagen peptide bond for supporting skin and elasticated net fracture, its
Spiral net-shaped structure is destroyed immediately, and skin histology is oxidized, atrophy, collapsed, and dryings, wrinkle, loose nothing just occurs in skin
The aging phenomenons such as elasticity.The enough collagens of supplement can stimulate the fibroblast in skin corium voluntarily to carry out collagen
Secretion so that voluntarily generting machanism and metabolic function recover normal to collagen, so effectively the relaxation of delaying skin with it is old
Change.Smeared with the lotion containing collagen after skin, epiderm skin and dermis can effectively improve, and promote skin
The synthesis of interior collagen.Real medical science often carries out beauty with collagen, and collagen can directly act on the impaired of skin corium
Collagenous fibres, make it recover transverse flow fiber configuration rapidly.In the unique triple-helix structure of collagen and collagen molecules
Hydrophilic group, enhances skin primary hydrodynamic force, it is ensured that moisture improves Lymphatic Circulation, made in the circulation of skin surface and deep layer
Skin water profit is full vibrant.But collagen molecules amount is big, and being directly added into cosmetics can not directly be absorbed by skin.
At present, what collagen production was extracted is mainly derived from three class materials：Ossein, deep-sea fish fish-skin, fish scale.Wherein
Ossein is easily obtained essentially from the animals such as pig, ox, sheep, raw material, and raw material source is stable, but the ossein that Animal Bone is extracted contains
Compared with fattiness, ossein purity is slightly lower, and beauty performance is slightly worse, and due to religion and Animal diseases, animal ossein
The market share it is less and less.Relative to ossein, fish skin collagen, scale collagen has the advantage of the two concurrently；And pass through
Detection, the hydroxyproline content of fish scale collagen is higher than other raw materials, due to collagen peptide in fish scale and application on human skin collagen
Structure it is similar, compatible good, the collagen product prepared by fish scale, it is easier to be absorbed by the skin.
But the collagen product anti-microbial property prepared by fish scale is poor, the easy breed bacteria on face is applied, not only not
It can play a part of protecting moisturizing, the growth of face bacterium be added on the contrary, it is impossible to use directly as cosmetics.
The content of the invention
In view of the shortcomings of the prior art, the main object of the present invention is to provide antibacterial fish scale protein facial mask and its preparation side
Method, it can effectively suppress the growth of bacterium, and human body is safe from harm, and will not produce allergic reaction.
To solve the above problems, the invention provides a kind of antibacterial fish scale protein facial mask, including following material：Fish scale albumen
Peptide, sodium hyaluronate, plant extraction liquid, Nano silver grain, glycerine, pyrrolidone sodium carboxylate, xanthans, film forming agent, deionized water.
It is preferred that, the antibacterial fish scale protein facial mask includes the material of following parts by weight：5~25 parts of fish scale protein peptide, glass
3~12 parts of uric acid, 1~20 part of plant extraction liquid, 0.5~3 part of Nano silver grain, 1~3 part of glycerine, pyrrolidone sodium carboxylate 1~
5 parts, 2~6 parts of xanthans, 3~8 parts of film forming agent, 50 parts of deionized water.
It is preferred that, the antibacterial fish scale protein facial mask includes the material of following parts by weight：8~22 parts of fish scale protein peptide, glass
5~10 parts of uric acid, 5~18 parts of plant extraction liquid, 1~1.5 part of Nano silver grain, 1~3 part of glycerine, pyrrolidone sodium carboxylate 1~
5 parts, 2~6 parts of xanthans, 3~8 parts of film forming agent, 50 parts of deionized water.
It is preferred that, the antibacterial fish scale protein facial mask includes the material of following parts by weight：18 parts of fish scale protein peptide, glass urine
8 parts of acid, 16 parts of plant extraction liquid, 1.5 parts of Nano silver grain, 2 parts of glycerine, 2 parts of pyrrolidone sodium carboxylate, 4 parts of xanthans, film forming
5 parts of agent, 50 parts of deionized water.
The effect of antibacterial bacteriostatic, Nano silver grain have been reached in the present invention by adding the Nano silver grain in facial mask
There is excellent biocompatibility with excellent antibacterial bacteriostatic performance, and with human body, allergy will not be caused to human body, preferably
, in the present invention, the Nano silver grain is in silver nanoparticle ball, silver nanotube, nano silver wire, silver nanotube or Nano silver piece
It is at least one.
In order to improve the bacteriostasis property of Nano silver grain, and the dispersive property in facial mask, it is preferred that the silver nanoparticle
The particle diameter of particle is 5~20nm, and the particle diameter estimation mode of the wherein Nano silver grain of different-shape is different, the grain of such as silver nanoparticle ball
Footpath is its diameter, and the particle diameter of silver nanotube is the diameter of section of nanotube, the diameter of section that the particle diameter of nano silver wire is, silver nanoparticle
The diameter of section that the particle diameter of pipe is, the particle diameter of Nano silver piece is its length of side.
In order to improve the applicability of facial mask, increase the function of facial mask, the plant extraction liquid is gadol extract, marine alga
Extract, safranine flower extract, water lily extract, green-tea extract, aloe extract, mint extract, pot marigold extract,
Honegsukle flower P.E, Herba Lysimachiae foenumgraeci extract, Bulbus Lilii extract, adnate elder herb extract, rose extract, camomile extract, lemon
In at least one of lemon extract, Rosmarinus officinalis extract, Ocimum sanctum P.E, grape seed extract, tuckahoe extracts, the present invention
The species of plant extraction liquid can be combined according to actual conditions.
The present invention also provides a kind of preparation method of antibacterial fish scale protein facial mask, comprises the following steps：
(1) collagen peptide is dissolved in acid solution, obtains albumen peptide solution；
(2) light trigger, Nano silver grain and inhibitor are scattered in solvent, the albumen then added in step (1)
Peptide solution, after being well mixed, regulation pH value of solution is 5~7, is placed under uviol lamp and irradiates 1~5h with ultraviolet；
(3) by after the ultrasonically treated 0.5~3h of product of step (2), with micro-pore-film filtration, filtrate is obtained, by filtrate successively
By zwitterion post deionization, fish scale protein peptide is obtained；
(4) by fish scale protein peptide and sodium hyaluronate, plant extraction liquid, Nano silver grain, glycerine, pyrrolidone sodium carboxylate, Huang
Virgin rubber, film forming agent are well mixed in water, that is, obtain antibacterial fish scale protein facial mask.
Nano silver grain is prepared using existing public technology in the present invention, and the present invention will not be repeated here.
In order to add the rate of dissolution of fish scale collagen, collagen peptide is dissolved in acid solution first,
It is preferred that, in step (1), the acid solution is the aqueous solution of acid, and the acid is in hydrochloric acid, citric acid, acetic acid, lactic acid
It is at least one.
According to the present invention, light trigger can make Nano silver grain under light conditions, be reacted with fish scale protein peptide,
It is preferred that, the light trigger is benzoin and its derivatives, 2,2- dimethoxy -2- phenyl acetophenones, thioxanthones, benzene
At least one of ketone class etc..
Protein peptides can react under ultraviolet light in the presence of photo initiator with Nano silver grain, it is preferred that
In step (2), the power density of the uviol lamp is 50~100 μ W/cm2, the wavelength of ultraviolet is 253.7nm.
It is preferred that, the inhibitor is at least one of diethanol amine, triethanolamine and acetylacetone,2,4-pentanedione.
By ultrasound, the solute in solution can be made uniformly to disperse, it is preferred that the ultrasonic frequency be 30~
40KHz。
Due to macromolecular it is difficult to which by percutaneous absorption, the present invention can remove big point in solution by filtering with microporous membrane
Son, it is preferred that the microporous barrier is the cellulose mixture miillpore filter that aperture is 10-30 μm.
It is preferred that, in step (5), the film forming agent be polyacrylic acid, polyacrylate sodium, polyvinylpyrrolidone,
At least one of hydroxymethyl cellulose, PVP and polyethylene glycol.
The preparation technology of the collagen peptide, comprises the following steps：
A, fish scale is taken, after cleaning, fish scale is soaked into 3~5h in the solution containing carbonate, fish scale is then placed in acid
Property solution in, with microwave treatment, then soak 3~12h with alkaline solution again, be washed out to neutrality, filtering, obtain filtrate 1
With filter residue 1；
B, by the filter residue processing with enzyme preparation in step A, washing and filtering obtains filtrate 2 and filter residue 2；
It is C, filtrate 1 and filtrate is 2-in-1 simultaneously, with filtering with microporous membrane, filtrate 3 is obtained, filtrate 3 is spray-dried, obtained
To fish scale collagen.
According to the present invention, the present invention is first handled the solution of fish scale carbonate, and carbonate solution being capable of loose fish scale
Middle fine and close collagen fabric, so as to facilitate subsequent treatment, improves the efficiency of subsequent treatment, it is preferred that described to contain carbonic acid
The solution of salt is the aqueous solution of the aqueous solution, preferably sodium carbonate and/or potassium carbonate of carbonate.
According to the present invention, in step, the acid solution is any solvent that pH is extremely less than 7, can be the water-soluble of acid
Liquid, the aqueous solution of strong acid weak base salt, phenol and its derivatives solution, are preferably the aqueous solution of acid, due to what is extracted in the present invention
Collagen is finally to be fabricated to facial mask, is applied on the face, and the acid is preferably harmless acid, and preferably concentration is less than
At least one of 0.1M hydrochloric acid, citric acid, acetic acid, lactic acid.
According to the present invention, microwave treatment can be destroyed the triple-helix structure of collagen, hydrogen bond therein and hydrophobic
Key is broken, by increasing capacitance it is possible to increase the efficiency of acid dissolving, it is preferred that in step, and the power of the microwave treatment is 400~900W；Institute
The time for stating microwave treatment is 0.5~15min.
It is preferred that, in step, the alkaline solution is alkali metal hydroxide and/or alkaline earth metal hydroxide
The aqueous solution.
It is preferred that, in stepb, the processing with enzyme preparation is concretely comprised the following steps：Jia 15 in filter residue in step~20
Amount water, adjusts control ph in 6.5~7.5, temperature at 45~55 DEG C again, adds enzyme preparation 1, the enzyme preparation 1 and filter residue ratio
For (0.5~3.0): 100,0.5~1.5h is stirred, 1~4h is incubated, enzyme preparation 1 is then inactivated；Control ph 1.0~3.0,
Temperature adds enzyme preparation 2 at 55~70 DEG C, and the enzyme preparation 2 is (0.1~3.0) with filter residue ratio: after 100,1~3h of stirring,
Inactivate enzyme preparation 2.
In stepb, the enzyme preparation 1 and enzyme preparation 2 are respectively neutral proteinase, papain, trypsase, stomach
At least one of protease.
The present invention can remove the macromolecular in solution by filtering with microporous membrane, it is preferred that described micro- in step C
Hole filter membrane is the cellulose mixture miillpore filter that aperture is 20-50 μm.
Compared with prior art, the present invention has following technique effect：
(1) present invention is with fish scale and raw material, and fish scale is biological material, harmless to the human body, can be degradable, to environment
It is pollution-free, also achieve the recycling of waste；
(2) present invention assigns the effect of facial mask antibacterial bacteriostatic by adding Nano silver grain in facial mask, and to human body thing
Any side effect, it is safe；
(2) present invention adds plant extraction liquid in facial mask, is cooperated by various active composition, makes the effective of facial mask
Composition gos deep into skin deep layer cells center, continues skin care and crease-resistant oxidation resistant function, prevents scaly dry skin, tight, wrinkle
The skin problems such as line, and do not stimulate gently, strengthen anti aging effect effect, while improve product odour, without adding essence,
Increase Product Safety and applicability.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, following examples, to present invention progress
It is further described.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to limit
The present invention.
Embodiment 1
A kind of antibacterial fish scale protein facial mask, by the material composition of following parts by weight：18 parts of fish scale protein peptide, 8 parts of sodium hyaluronate,
16 parts of gadol extract, 1.5 parts of silver nanoparticle ball, 2 parts of glycerine, 2 parts of pyrrolidone sodium carboxylate, 4 parts of xanthans, polyacrylic acid into
5 parts of film, 50 parts of deionized water；
The present embodiment additionally provides the preparation method of the antibacterial fish scale protein facial mask, comprises the following steps：
(1) collagen peptide is dissolved in hydrochloric acid solution, obtains albumen peptide solution；
The preparation method of described collagen peptide is：By fish scale successively use sodium carbonate liquor, hydrochloric acid solution in, hydrogen
After sodium hydroxide solution and processing with enzyme preparation, filtration drying, that is, collagen peptide is obtained,
Wherein, the processing with enzyme preparation is concretely comprised the following steps：By in 16 times of amount water of addition after acid treatment and alkali process, adjust
Control ph is saved in 7, temperature at 50 DEG C, neutral proteinase is added, the neutral proteinase and filter residue ratio are 2: 100, stir 1h,
2h is incubated, neutral proteinase is then inactivated；Control ph adds papain in 2.0, temperature at 60 DEG C, the Papain
Enzyme and filter residue ratio are 2: 100, after stirring 2h, inactivate papain；
(2) silver nanoparticle ball, light trigger benzoin and its derivatives and inhibitor diethanol amine are scattered in solvent, so
The albumen peptide solution added afterwards in step (1), after being well mixed, regulation pH value of solution is 6, is placed under uviol lamp and is irradiated with ultraviolet
2h, the power density of the uviol lamp is 60 μ W/cm2, the wavelength of ultraviolet is 253.7nm；
(3) by the ultrasonically treated 2h of product of step (2), the ultrasonic frequency is 35KHz, with the mixing that aperture is 20 μm
Cellulose microporosity filter membrane is filtered, and obtains filtrate, filtrate is passed sequentially through into zwitterion post deionization；
(4) by fish scale protein peptide and sodium hyaluronate, gadol extract, silver nanoparticle ball, glycerine, pyrrolidone sodium carboxylate, Huang
Virgin rubber, polyacrylic acid film forming agent are well mixed in water, that is, obtain antibacterial fish scale protein facial mask.
Embodiment 2
A kind of antibacterial fish scale protein facial mask, by the material composition of following parts by weight：8 parts of fish scale protein peptide, 5 parts of sodium hyaluronate,
5 parts of marine algae extract, 1 part of silver nanotube, 1 part of glycerine, 1 part of pyrrolidone sodium carboxylate, 2 parts of xanthans, polyacrylate sodium into
3 parts of film, 50 parts of deionized water；
The present embodiment additionally provides the preparation method of the antibacterial fish scale protein facial mask, comprises the following steps：
(1) collagen peptide is dissolved in citric acid solution, obtains albumen peptide solution；
The preparation method of described collagen peptide is：Fish scale is used in solution of potassium carbonate, citric acid solution successively,
After potassium hydroxide solution and processing with enzyme preparation, filtration drying, that is, collagen peptide is obtained,
Wherein, the processing with enzyme preparation is concretely comprised the following steps：By in 18 times of amount water of addition after acid treatment and alkali process, adjust
Control ph is saved in 7.1, temperature at 52 DEG C, papain is added, the papain and filter residue ratio are 1: 100, stirring
1h, is incubated 4h, then inactivates papain；Control ph adds trypsase in 2.0, temperature at 60 DEG C, the tryptose
Enzyme and filter residue ratio are 2: 100, after stirring 2h, inactivate trypsase；
(2) silver nanotube, light trigger 2,2- dimethoxy -2- phenyl acetophenones and inhibitor triethanolamine are scattered in
In solvent, the albumen peptide solution then added in step (1), after being well mixed, regulation pH value of solution is 6, is placed under uviol lamp and uses
Ultraviolet irradiates 3h, and the power density of the uviol lamp is 70 μ W/cm2, the wavelength of ultraviolet is 253.7nm；
(3) by the ultrasonically treated 1h of product of step (2), the ultrasonic frequency is 35KHz, with the mixing that aperture is 25 μm
Cellulose microporosity filter membrane is filtered, and obtains filtrate, filtrate is passed sequentially through into zwitterion post deionization；
(4) by fish scale protein peptide and sodium hyaluronate, marine algae extract, silver nanotube, glycerine, pyrrolidone sodium carboxylate, xanthan
Glue, polyacrylate sodium film forming agent are well mixed in water, that is, obtain antibacterial fish scale protein facial mask.
Embodiment 3
A kind of antibacterial fish scale protein facial mask, by the material composition of following parts by weight：22 parts of fish scale protein peptide, sodium hyaluronate 10
Part, 18 parts of safranine flower extract, 1.5 parts of nano silver wire, 3 parts of glycerine, 5 parts of pyrrolidone sodium carboxylate, 6 parts of xanthans, polyethylene
8 parts of pyrrolidones film forming agent, 50 parts of deionized water；
The present embodiment additionally provides the preparation method of the antibacterial fish scale protein facial mask, comprises the following steps：
(1) collagen peptide is dissolved in citric acid solution, obtains albumen peptide solution；
The preparation method of described collagen peptide is：By fish scale successively with the solution containing sodium carbonate, citric acid
In solution, sodium hydroxide solution and processing with enzyme preparation, after filtration drying, that is, obtain collagen peptide,
Wherein, the processing with enzyme preparation is concretely comprised the following steps：By in 15 times of amount water of addition after acid treatment and alkali process, adjust
Control ph is saved in 6.5, temperature at 45 DEG C, papain is added, the papain and filter residue ratio are 1: 100, stirring
1.0h, is incubated 2h, then inactivates papain；Control ph adds neutral proteinase in 2.0, temperature at 60 DEG C, in this
Property protease and filter residue ratio be 2: 100, stirring 2h after, inactivate neutral proteinase；
(2) nano silver wire, thioxanthone photoinitiator and triethanolamine inhibitor are scattered in solvent, then added
Albumen peptide solution in step (1), after being well mixed, regulation pH value of solution is 5, is placed under uviol lamp and irradiates 1h, institute with ultraviolet
The power density for stating uviol lamp is 50 μ W/cm2, the wavelength of ultraviolet is 253.7nm；
(3) by the ultrasonically treated 3h of product of step (2), the ultrasonic frequency is 40KHz, with the mixing that aperture is 10 μm
Cellulose microporosity filter membrane is filtered, and obtains filtrate, filtrate is passed sequentially through into zwitterion post deionization；
(4) by fish scale protein peptide and sodium hyaluronate, safranine flower extract, nano silver wire, glycerine, pyrrolidone sodium carboxylate, Huang
Virgin rubber, polyvinylpyrrolidone film forming agent are well mixed in water, that is, obtain antibacterial fish scale protein facial mask.
Embodiment 4
A kind of antibacterial fish scale protein facial mask, by the material composition of following parts by weight：5 parts of fish scale protein peptide, 3 parts of sodium hyaluronate,
1 part of green-tea extract, 0.5 part of Nano silver piece, 1 part of glycerine, 1 part of pyrrolidone sodium carboxylate, 2~6 parts of xanthans, hydroxylmethyl cellulose
Plain 3 parts of film forming agent, 50 parts of deionized water；
The present embodiment additionally provides the preparation method of the antibacterial fish scale protein facial mask, comprises the following steps：
(1) collagen peptide is dissolved in acetum, obtains albumen peptide solution；
The preparation method of described collagen peptide is：By fish scale successively use solution of potassium carbonate, acetum in, hydrogen
After potassium oxide solution and processing with enzyme preparation, filtration drying, that is, collagen peptide is obtained,
Wherein, the processing with enzyme preparation is concretely comprised the following steps：By in 20 times of amount water of addition after acid treatment and alkali process, adjust
Control ph is saved in 7.5, temperature at 55 DEG C, trypsase is added, the trypsase and filter residue ratio are 3: 100, stir 1.5h,
4h is incubated, trypsase is then inactivated；Control ph adds papain in 2.0, temperature at 70 DEG C, the papain
It is 2: 100 with filter residue ratio, after stirring 2h, inactivates papain；
(2) Nano silver piece, benzoin and its derivatives light trigger and acetylacetone,2,4-pentanedione inhibitor are scattered in solvent, so
The albumen peptide solution added afterwards in step (1), after being well mixed, regulation pH value of solution is 7, is placed under uviol lamp and is irradiated with ultraviolet
5h, the power density of the uviol lamp is 100 μ W/cm2, the wavelength of ultraviolet is 253.7nm；
(3) by the ultrasonically treated 3h of product of step (2), the ultrasonic frequency is 40KHz, with the mixing that aperture is 30 μm
Cellulose microporosity filter membrane is filtered, and obtains filtrate, filtrate is passed sequentially through into zwitterion post deionization；
(4) by fish scale protein peptide and sodium hyaluronate, green-tea extract, Nano silver piece, glycerine, pyrrolidone sodium carboxylate, xanthan
Glue, hydroxymethyl cellulose film forming agent are well mixed in water, that is, obtain antibacterial fish scale protein facial mask.
Embodiment 5
A kind of antibacterial fish scale protein facial mask, by the material composition of following parts by weight：25 parts of fish scale protein peptide, sodium hyaluronate 12
Part, 20 parts of aloe extract, 3 parts of silver nanoparticle ball, 3 parts of glycerine, 5 parts of pyrrolidone sodium carboxylate, 6 parts of xanthans, polyvinyl pyrrole
8 parts of alkanone film forming agent, 50 parts of deionized water；
The present embodiment additionally provides the preparation method of the antibacterial fish scale protein facial mask, comprises the following steps：
(1) collagen peptide is dissolved in hydrochloric acid solution, obtains albumen peptide solution；
The preparation method of described collagen peptide is：By fish scale successively use solution of potassium carbonate, hydrochloric acid solution in, hydrogen
After potassium oxide solution and processing with enzyme preparation, filtration drying, that is, collagen peptide is obtained,
Wherein, the processing with enzyme preparation is concretely comprised the following steps：By in 15 times of amount water of addition after acid treatment and alkali process, adjust
Control ph is saved in 7.5, temperature at 55 DEG C, pepsin is added, the pepsin and filter residue ratio are 1.2: 100, stirring
1.3h, is incubated 2h, then inactivated pepsin；Control ph adds trypsase in 2, temperature at 60 DEG C, the trypsase
It is 2.4: 100 with filter residue ratio, after stirring 2h, inactivates trypsase；
(2) silver nanoparticle ball, light trigger 2,2- dimethoxy -2- phenyl acetophenones and inhibitor diethanol amine are scattered in
In solvent, the albumen peptide solution then added in step (1), after being well mixed, regulation pH value of solution is 6, is placed under uviol lamp and uses
Ultraviolet irradiates 2h, and the power density of the uviol lamp is 80 μ W/cm2, the wavelength of ultraviolet is 253.7nm；
(3) by the ultrasonically treated 3h of product of step (2), the ultrasonic frequency is 40KHz, with the mixing that aperture is 30 μm
Cellulose microporosity filter membrane is filtered, and obtains filtrate, filtrate is passed sequentially through into zwitterion post deionization；
(4) by fish scale protein peptide and sodium hyaluronate, aloe extract, silver nanoparticle ball, glycerine, pyrrolidone sodium carboxylate, xanthan
Glue, polyvinylpyrrolidone film forming agent are well mixed in water, that is, obtain antibacterial fish scale protein facial mask.
Foregoing description is only the description to section Example of the present invention, not to any restriction of the scope of the invention, one's own profession
The those of ordinary skill of industry can make improvement according to the present invention or change to above-described embodiment, but belong to present invention protection model
Enclose.
Claims (10)
1. a kind of antibacterial fish scale protein facial mask, it is characterised in that including following material：Fish scale protein peptide, sodium hyaluronate, plant extract
Liquid, Nano silver grain, glycerine, pyrrolidone sodium carboxylate, xanthans, film forming agent, deionized water.
2. antibacterial fish scale protein facial mask according to claim 1, it is characterised in that include the material of following parts by weight：Fish
5~25 parts of squama protein peptides, 3~12 parts of sodium hyaluronate, 1~20 part of plant extraction liquid, 0.5~3 part of Nano silver grain, glycerine 1~3
Part, 1~5 part of pyrrolidone sodium carboxylate, 2~6 parts of xanthans, 3~8 parts of film forming agent, 50 parts of deionized water.
3. antibacterial fish scale protein facial mask according to claim 1, it is characterised in that include the material of following parts by weight：Fish
8~22 parts of squama protein peptides, 5~10 parts of sodium hyaluronate, 5~18 parts of plant extraction liquid, 1~1.5 part of Nano silver grain, glycerine 1~3
Part, 1~5 part of pyrrolidone sodium carboxylate, 2~6 parts of xanthans, 3~8 parts of film forming agent, 50 parts of deionized water.
4. antibacterial fish scale protein facial mask according to claim 1, it is characterised in that include the material of following parts by weight：Fish
18 parts of squama protein peptides, 8 parts of sodium hyaluronate, 16 parts of plant extraction liquid, 1.5 parts of Nano silver grain, 2 parts of glycerine, pyrrolidone sodium carboxylate 2
Part, 4 parts of xanthans, 5 parts of film forming agent, 50 parts of deionized water.
5. the antibacterial fish scale protein facial mask according to Claims 1 to 4 any one, it is characterised in that the nano grain of silver
Son at least one of for silver nanoparticle ball, silver nanotube, nano silver wire, silver nanotube or Nano silver piece, and/or
The particle diameter of the Nano silver grain is 5~20nm.
6. antibacterial fish scale protein facial mask according to claim 5, it is characterised in that the plant extraction liquid carries for rhodiola root
Take thing, marine algae extract, safranine flower extract, water lily extract, green-tea extract, aloe extract, mint extract, golden small cup
Flower extract, Honegsukle flower P.E, Herba Lysimachiae foenumgraeci extract, Bulbus Lilii extract, adnate elder herb extract, rose extract, chamomile
At least one in extract, lemon extract, Rosmarinus officinalis extract, Ocimum sanctum P.E, grape seed extract, tuckahoe extracts
Kind.
7. a kind of preparation method of antibacterial fish scale protein facial mask according to claim 1~6 any one, its feature exists
In comprising the following steps：
(1) collagen peptide is dissolved in acid solution, obtains albumen peptide solution；
(2) light trigger, Nano silver grain and inhibitor are scattered in solvent, the protein peptides then added in step (1) are molten
Liquid, after being well mixed, regulation pH value of solution is 5~7, is placed under uviol lamp and irradiates 1~5h with ultraviolet；
(3) by after the ultrasonically treated 0.5~3h of product of step (2), with micro-pore-film filtration, filtrate is obtained, filtrate is passed sequentially through
Zwitterion post deionization, obtains fish scale protein peptide；
(4) by fish scale protein peptide and sodium hyaluronate, plant extraction liquid, Nano silver grain, glycerine, pyrrolidone sodium carboxylate, xanthans,
Film forming agent is well mixed in water, that is, obtains antibacterial fish scale protein facial mask.
8. the preparation method of antibacterial fish scale protein facial mask according to claim 1, it is characterised in that in step (1), institute
The aqueous solution of the acid solution for acid is stated, the acid is at least one of hydrochloric acid, citric acid, acetic acid, lactic acid.
9. the preparation method of the antibacterial fish scale protein facial mask according to claim 7 or 8, it is characterised in that in step (2)
In, the power density of the uviol lamp is 50~100 μ W/cm2, the wavelength of ultraviolet is 253.7nm；And/or
The microporous barrier is the cellulose mixture miillpore filter that aperture is 10-30 μm.
10. the preparation method of the antibacterial fish scale protein facial mask according to claim 7 or 8, it is characterised in that the fish glue from scale
The preparation method of former protein peptides is：
By in 15~20 times of the addition amount water after acid treatment and alkali process, regulation control ph 6.5~7.5, temperature 45~
55 DEG C, enzyme preparation 1 is added, the enzyme preparation 1 is (0.5~3.0) with filter residue ratio: 100,0.5~1.5h is stirred, 1~4h is incubated,
Then enzyme preparation 1 is inactivated；Control ph adds enzyme preparation 2 in 1.0~3.0, temperature at 55~70 DEG C, the enzyme preparation 2 and filter
Slag ratio example is (0.1~3.0): after 100,1~3h of stirring, inactivates enzyme preparation 2；
Wherein, the enzyme preparation 1 and enzyme preparation 2 are respectively in neutral proteinase, papain, trypsase, pepsin
At least one.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111329794A (en) * | 2020-04-27 | 2020-06-26 | 杭州协合医疗用品有限公司 | Fish scale collagen nourishing and repairing mask and application thereof |
| CN115137681A (en) * | 2022-06-23 | 2022-10-04 | 深圳市黄田荔枝品牌发展有限公司 | Litchi mask and preparation method thereof |
| US11786451B2 (en) | 2019-06-28 | 2023-10-17 | The Procter & Gamble Company | Skin care composition |
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| CN104490732A (en) * | 2014-12-10 | 2015-04-08 | 内蒙古天奇生物科技有限公司 | Anti-aging scale collagen polypeptide facial mask and preparation method thereof |
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| KR20140130596A (en) * | 2013-05-01 | 2014-11-11 | (주)청룡수산 | A cosmetic composition comprising enzymatic extracts from branchiostegus japonicus |
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| US11786451B2 (en) | 2019-06-28 | 2023-10-17 | The Procter & Gamble Company | Skin care composition |
| CN111329794A (en) * | 2020-04-27 | 2020-06-26 | 杭州协合医疗用品有限公司 | Fish scale collagen nourishing and repairing mask and application thereof |
| CN115137681A (en) * | 2022-06-23 | 2022-10-04 | 深圳市黄田荔枝品牌发展有限公司 | Litchi mask and preparation method thereof |
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Application publication date: 20171020 |