CN107252339B - Intravascular Thrombus suction system - Google Patents

Intravascular Thrombus suction system Download PDF

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Publication number
CN107252339B
CN107252339B CN201610230786.5A CN201610230786A CN107252339B CN 107252339 B CN107252339 B CN 107252339B CN 201610230786 A CN201610230786 A CN 201610230786A CN 107252339 B CN107252339 B CN 107252339B
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Prior art keywords
drive module
blood
suction catheter
thrombus
motor
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CN201610230786.5A
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Chinese (zh)
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CN107252339A (en
Inventor
唐智荣
郑淇文
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Fengkai Medical Devices (shanghai) Co Ltd
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Fengkai Medical Devices (shanghai) Co Ltd
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Publication of CN107252339A publication Critical patent/CN107252339A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00778Operations on blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22079Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with suction of debris
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/75General characteristics of the apparatus with filters

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention discloses a kind of Intravascular Thrombus suction systems, suction catheter and drive module including human body can be percutaneously implantable, the suction catheter includes into blood mouth, channel of blood flow and blood outlet, it is provided with strainer in the channel of blood flow of the suction catheter, is provided with impeller between the strainer and blood outlet or at blood outlet;The impeller is connected with the drive module.Intravascular Thrombus suction system provided by the invention takes bolt safer without blocking blood flow using the Smoking regime of negative pressure, is not concerned about thrombus and fractures and flakes off.Relative to existing suction catheter technology, when using suction catheter provided by the invention, patient blood is returned to blood circulation without blood loss after passing through the filter screen, and thrombus also removes together when conduit withdraws from external.

Description

Intravascular Thrombus suction system
Technical field
The invention belongs to medical instruments field more particularly to a kind of Intravascular Thrombus suction systems.
Background technique
Thrombosis (thrombosis) refers to that under certain condition, blood formed element forms embolus in the blood vessels, makes At vasculature part or completely plugged, the pathologic process of corresponding site blood supply obstacle.It is small that blood can be divided into according to thrombus constituent Plate thrombus, red blood cell thrombus, fibrinous thrombus, mixed thrombus etc..Arteriosity thrombus, veins blood can be divided by blood vessel type Bolt and capillary thrombus.
Thromboembolism (thromboembolism) is that thrombus is fallen off by forming part, during mobile with blood flow Divide or all block certain blood vessels, causes respective organization and (or) organ ischemia, anoxic, necrosis (arterial thrombus) and extravasated blood, water The pathologic process of swollen (phlebothrombosis).
The thrombotic diseases as caused by two kinds of pathologic processes of thrombosis and thromboembolism seriously threaten the life of the mankind Health, disease incidence are in first of various diseases, and due to activity reduction in the work of internet bring, life, thrombotic disease There are also cumulative gesture in recent years for disease, are one of emphasis and hot spot of contemporary medical science research.
The cause of disease of thrombotic diseases specifically includes that age factor, movable reduction, vascular inflammation etc..Pulmonary embolism (PE) is also known as Pulmonary thromboembolism is to cause facing for disturbance of pulmonary circulation due to endogenous or exogenous embolus blocking main pulmonary artery or branch Bed performance and pathologic, physiologic syndrome.Such as further occurrence empsyxis or bad the dead on this basis, i.e. referred to as pulmonary infarction.Postmortem Data shows the generation age of PE mostly at 50~65 years old, and child morbidity rate is about 3%.And 60 years old or more reachable 20%.90% causes Dead property PE occurs at 50 years old or more.It is 10 times high in the incidence male more of the same age of the person of women 20~39 years old its deep vein thrombosis, therefore The incidence of PE is opposite to be increased.In addition because of reasons such as fracture of lower limb, paralysis, severe heart and lung diseases, operations, cause long-term inappropriate Bed or Healthy People usually limb activity is reduced, reduce the driving force of venous blood flow, also result in stasis of blood stream, it is deep quiet Arteries and veins thrombosis.
The essential therapeutic arsenals of thrombotic diseases include: the drug therapies such as anticoagulant, anti-bolt, thrombolysis at present, operative treatment with And interventional therapy etc..It is ineffective through medical treatment to oldness thrombus and Doppler flow mapping forms bad person, it is contemplated that operation is controlled It treats, that is, removal of thromboses or the excision vascular embolization section of performing the operation simultaneously are coincide again.Interventional therapy passes through conduit by conduit local thrombolysis Negative-pressure ward thrombus and bolt is taken by the appliance mechanisms formula such as sacculus, bracket.
It after thrombosis, is easy to fall off and with blood flow, partly or entirely blocks certain blood vessels in mobile process, draw Play respective organization and (or) organ ischemia, anoxic, necrosis etc..Position and the embolism of severity and embolism that thromboembolism influences Time it is related.
The drug therapies such as anticoagulant, anti-bolt, thrombolysis are needed to entire blood circulation system medication, and dosage is big, slow effect, Easily cause the complication such as organ internal organs bleeding.
The interventional therapy of thrombolytic drug injection part can be reduced by dose by conduit at present, reduction follows entire blood The influence of loop system, but still there are slow effect.
Thrombus especially fresh thrombus is easily broken as jelly without mechanical strength in vivo in vivo.It is taken by sacculus Bolt needs to block Distal blood flow, in order to take bolt complete as far as possible, takes bolt sacculus to need adherent, is easy to scratch blood vessel when moving, lead to Bracket is crossed to take bolt that thrombus is easy to cause to rupture and take bolt incomplete.
Conduit negative-pressure ward thrombus includes manual suction and Bernoulli effect by Biochemical analyzer to external at present.Suction manually Unstable and suction force is small, almost without clinical efficacy.It is aspirated using Bernoulli effect, the course of work is that transfer tube generates arteries and veins Physiological saline is injected through conduit and washes away thrombus from the hole contra-injection of conductor housing end side by stamping press, and high speed physiological saline produces simultaneously Raw local depression area, is sucked out the embolic particles of fragmentation by conduit tap.The disadvantage of this method is that by Biochemical analyzer To it is external while, blood is also pumped in vitro together, and blood volume in patients is caused to reduce.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of Intravascular Thrombus suction systems, to thrombotic diseases patient There is provided what one kind percutaneously used, the equipment for quickly, effectively removing thrombus, system does not reduce blood volume while removing thrombus, With higher validity and safety, and it is not necessarily to surgical operation.
The present invention to solve above-mentioned technical problem and the technical solution adopted is that provide a kind of Intravascular Thrombus suction system, Suction catheter and drive module including that can be percutaneously implantable human body, the suction catheter include into blood mouth, channel of blood flow and bleeding Mouthful, it is provided with strainer in the channel of blood flow of the suction catheter, is provided with leaf between the strainer and blood outlet or at blood outlet Wheel;The impeller is connected with the drive module.
Further, the drive module be located at be provided separately in vitro with the suction catheter, the drive module it is remote End is connected by flexible transmission structure with the suction catheter, the drive module proximally by signal wire and control module phase Even.
Further, the flexible transmission structure includes driving seal wire and provides the biography of drive cavity for the driving seal wire Dynamic conduit, the driving seal wire are connected by bridging structure with the impeller.
Further, the length range of the flexible transmission structure is 80cm~200cm, and the driving seal wire twines for spiral Around pipe or steel strand wires.
Further, the drive module includes support housing, drive motor and bridging structure, the drive module bridge joint The distal end of structure connects the driving seal wire in the flexible transmission structure, described in the proximal end connection of the drive module bridging structure The shaft of drive motor.
Further, the drive motor is air motor, is additionally provided with cooling structure in the support housing, test the speed knot Structure, exhaust structure and denoising structure, the control module export the output gas of control signal control gas source to the drive module Pressure controls steamer revolving speed, while speed-measuring structure feedback steamer actual speed is used to form closed-loop control.
Further, the drive motor is electric motor, is additionally provided with cooling structure, the control in the support housing Molding block provides driving signal electromechanical source, the operating status of the drive module feedback motor to the drive module.
Further, the drive module is the control module position that is connected with the drive module positioned at intracorporal motor In external.
Further, the control module includes the system software that controller main body, electrical system and controller carry, and With human-computer interaction interface;The controller main body is connected with the drive module by signal wire, and the controller main body passes Send and receive the operating parameter of the drive module inner motor;The system software is for being arranged system operational parameters, control system System operation, the operating status for monitoring the suction catheter in real time.
Further, the mesh area range of the strainer is 0.1mm2-16mm2
The present invention, which compares the prior art, to be had following the utility model has the advantages that Intravascular Thrombus suction system provided by the invention, drives The driving device of movable vane wheel rotation can be located at internal or external.Impeller high speed rotation when driving device high speed rotation, is entering Blood mouth forms negative pressuren zone, and the blood containing thrombus is sucked suction catheter, and when through filter screen, blood can pass through, but be greater than filter The thrombus of net mesh can not then pass through, and so as to separate thrombus and blood, blood returns to blood vessel by blood outlet.Relatively Bolt mode is taken in balloon-stent etc., Intravascular Thrombus suction system provided by the invention is not necessarily to blocking blood flow, using the pumping of negative pressure Suction mode takes bolt safer, is not concerned about thrombus and fractures and flakes off.Relative to existing suction catheter technology, mentioned using the present invention When the Intravascular Thrombus suction system of confession, patient blood is returned to blood circulation without blood loss after passing through the filter screen, and conduit withdraws from body Thrombus also removes together when outer.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of Intravascular Thrombus suction system of the present invention;
Fig. 2 is the operation schematic diagram of Intravascular Thrombus suction system of the present invention.
In figure:
1 suction catheter, 2 strainer, 3 impeller
11 enter 12 blood outlet of blood mouth, 13 channel of blood flow
4 transmission 5 blood vessel of conduit, 6 thrombus
7 blood
Specific embodiment
The invention will be further described with reference to the accompanying drawings and examples.
Fig. 1 is the structural schematic diagram of Intravascular Thrombus suction system of the present invention.
Referring to Figure 1, Intravascular Thrombus suction system provided by the invention, the suction catheter including human body can be percutaneously implantable 1 and drive module (not shown), suction catheter 1 include into blood mouth 11, channel of blood flow 13 and blood outlet 12, the blood of suction catheter 1 It is provided with strainer 2 in circulation road 13, rotatable impeller 3 is provided between strainer 2 and blood outlet 12 or at blood outlet 12;Impeller 3 are connected with the drive module.Preferably, the mesh area range of strainer 2 is 0.1mm2-16mm2
In Intravascular Thrombus suction system provided by the invention, the drive module can be for positioned at intracorporal motor, leaf Wheel 3 can be located at external by internal motor driven, control module.In the present embodiment, preferably, the drive module is located at body It is provided separately with suction catheter 1, is carried out specifically using the structure of drive module setting in vitro as specific embodiment below outside It is bright.
Intravascular Thrombus suction system provided in this embodiment, the distal end of the drive module by flexible transmission structure with Suction catheter 1 is connected, and the drive module is connected proximally by signal wire with control module.The flexible transmission structure includes It drives seal wire and provides the transmission conduit 4 of drive cavity for the driving seal wire, the driving seal wire passes through bridging structure and leaf Wheel 3 is connected.Preferably, the length range of the flexible transmission structure is 80cm~200cm, and the driving seal wire is spiral winding Pipe or steel strand wires.The drive module includes support housing, drive motor and bridging structure, the drive module bridging structure Distal end connects the driving seal wire in the flexible transmission structure, and the proximal end of the drive module bridging structure connects the driving horse The shaft reached.
In the present embodiment, the drive motor can be air motor or electric motor, and the drive motor is pneumatic horse Up to when, be additionally provided with cooling structure, speed-measuring structure, exhaust structure and denoising structure, the control module in the support housing The output pressure for exporting control signal control gas source to the drive module controls steamer revolving speed, while the knot that tests the speed Structure feedback steamer actual speed is used to form closed-loop control.When the drive motor is electric motor, in the support housing also It is provided with cooling structure, the control module provides driving signal electromechanical source, the drive module feedback to the drive module The operating status of motor.
The control module includes the system software that controller main body, electrical system and controller carry, and is had man-machine Interactive interface;The controller main body is connected with the drive module by signal wire, and the controller main body is transmitted and received The operating parameter of the drive module inner motor;The system software is used to be arranged system operational parameters, control system is run, real When monitor the operating status of the suction catheter.
When beginning to use, operating parameter to controller input control parameter and is converted to by controller by man-machine interface; Controller sends driving signal to drive module by signal wire when operation, and control drive module inner motor is joined according to set operation Number operation;Driving torque is transferred to the impeller 3 in suction catheter 1 by flexible transmission structure by drive module, and impeller 3 rotates, Blood and thrombus 6 are together from the sucking of blood mouth 11 is entered, and when through filter screen 2, blood normally can be by flowing out into from blood outlet 12 Blood circulation system, thrombus 6 stay on strainer 2.When suction catheter 1 removes external, thrombus 6 follows suction catheter 1 to remove together In vitro.
To sum up, the driving device of driving impeller rotation can be located at internal or external.1 percutaneous access of suction catheter has thrombus Artery or vein.3 high speed rotation of impeller when driving device high speed rotation forms negative pressuren zone entering blood mouth 11, will contain blood The blood of bolt 6 sucks suction catheter 1, and when through filter screen 2, blood 7 can pass through, but the thrombus 6 for being greater than 2 mesh of strainer then can not Pass through, so as to separate thrombus 6 and blood 7, blood 7 returns to blood vessel 5 by blood outlet 12.Relative to balloon-stent etc. Bolt mode is taken, Intravascular Thrombus suction system provided by the invention takes bolt more using the Smoking regime of negative pressure without blocking blood flow Safety, is not concerned about and fractures and flakes off.Relative to existing suction catheter technology, aspirated using Intravascular Thrombus provided by the invention When system, patient blood is returned to blood circulation after filter screen 2 and without blood loss, thrombus also one when suction catheter 1 withdraws from external And it removes.
Although the present invention is disclosed as above with preferred embodiment, however, it is not to limit the invention, any this field skill Art personnel, without departing from the spirit and scope of the present invention, when can make a little modification and perfect therefore of the invention protection model It encloses to work as and subject to the definition of the claims.

Claims (7)

1. a kind of Intravascular Thrombus suction system, which is characterized in that suction catheter and driving mould including human body can be percutaneously implantable Block, the suction catheter include being provided with filter in the channel of blood flow of the suction catheter into blood mouth, channel of blood flow and blood outlet Net is provided with impeller between the strainer and blood outlet or at blood outlet;The impeller is connected with the drive module;
The drive module is located to be provided separately with the suction catheter in vitro, and the distal end of the drive module passes through Flexible Transmission Structure is connected with the suction catheter, and the drive module is connected proximally by signal wire with control module;
The drive module includes support housing, drive motor and bridging structure, and the distal end of the drive module bridging structure connects The driving seal wire in the flexible transmission structure is connect, the proximal end of the drive module bridging structure connects turning for the drive motor Axis;
The drive motor is electric motor, is additionally provided with cooling structure in the support housing, and the control module is to described Drive module provides driving signal electromechanical source, the operating status of the drive module feedback motor.
2. Intravascular Thrombus suction system as described in claim 1, which is characterized in that the flexible transmission structure includes driving Seal wire and the transmission conduit of drive cavity is provided for the driving seal wire, the driving seal wire passes through bridging structure and the impeller It is connected.
3. Intravascular Thrombus suction system as claimed in claim 2, which is characterized in that the length model of the flexible transmission structure It encloses for 80cm~200cm, the driving seal wire is spiral winding pipe or steel strand wires.
4. Intravascular Thrombus suction system as described in claim 1, which is characterized in that the drive motor is air motor, It is additionally provided with cooling structure, speed-measuring structure, exhaust structure and denoising structure in the support housing, the control module is to described The output pressure of drive module output control signal control gas source controls steamer revolving speed, while the speed-measuring structure is fed back Steamer actual speed is used to form closed-loop control.
5. Intravascular Thrombus suction system as described in claim 1, which is characterized in that the drive module is positioned at intracorporal Motor, the control module being connected with the drive module are located at external.
6. Intravascular Thrombus suction system as claimed in claim 1 or 5, which is characterized in that the control module includes control The system software that device main body, electrical system and controller carry, and there is human-computer interaction interface;The controller main body with it is described Drive module is connected by signal wire, and the controller main body transmits and receives the operating parameter of the drive module inner motor; The system software is used to be arranged system operational parameters, control system operation, the operating status for monitoring the suction catheter in real time.
7. Intravascular Thrombus suction system as described in claim 1, which is characterized in that the mesh area range of the strainer is 0.1mm2-16mm2
CN201610230786.5A 2016-04-14 2016-04-14 Intravascular Thrombus suction system Active CN107252339B (en)

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CN107252339B true CN107252339B (en) 2019-11-08

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EP4233989A3 (en) 2017-06-07 2023-10-11 Shifamed Holdings, LLC Intravascular fluid movement devices, systems, and methods of use
EP3710076B1 (en) 2017-11-13 2023-12-27 Shifamed Holdings, LLC Intravascular fluid movement devices, systems, and methods of use
EP4085965A1 (en) 2018-02-01 2022-11-09 Shifamed Holdings, LLC Intravascular blood pumps and methods of use and manufacture
WO2021011473A1 (en) 2019-07-12 2021-01-21 Shifamed Holdings, Llc Intravascular blood pumps and methods of manufacture and use
WO2021016372A1 (en) 2019-07-22 2021-01-28 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
WO2021062265A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Intravascular blood pump systems and methods of use and control thereof
CN111685852B (en) * 2020-07-21 2021-04-27 河南省中医院(河南中医药大学第二附属医院) Special pincers of neonate's umbilical cord edema of obstetrical department
CN113262016B (en) * 2021-06-03 2022-04-08 皖南医学院第一附属医院(皖南医学院弋矶山医院) Calculus smashing and melting device for urology department
CN115414580B (en) * 2022-11-07 2023-02-07 心凯诺医疗科技(上海)有限公司 Thrombus aspiration catheter

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CN103284774A (en) * 2013-05-22 2013-09-11 刘凤永 Gas-injection thrombosis-removal device and application thereof
CN103932756A (en) * 2014-03-21 2014-07-23 吴智群 Thrombus aspiration system
CN204121481U (en) * 2014-09-30 2015-01-28 广东省心血管病研究所 Left ventricle assist axle pump
CN105288766A (en) * 2015-10-12 2016-02-03 李卫校 Thrombus filtration and recovery device

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