CN107233544A - It is a kind of to treat decoction medicine of Severe Acute Pancreatitis SAP and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of decoction medicine for treating Severe Acute Pancreatitis SAP provided according to the understanding mechanism of Chinese traditional treatment Severe Acute Pancreatitis SAP, each component and its mass parts ratio of the medicine is as follows：Oriental wormwood 14g, Glabrous Sarcandra Herb 14g, giant knotweed 14g, rhizoma imperatae 28g, linseed 10g, corydalis tuber 14g, desmodium 50g, radix bupleuri 10g, radix scutellariae 14g, Chinese herbaceous peony 10g, tuber of pinellia 7g, red sage root 14g, ginger 10g, jujube 13g, rheum officinale 12g, cape jasmine（Fry）20g, saltcake 14g, dried immature fruit of citron orange 10g, bark of official magnolia 10g, root of gansui 6g, radix glycyrrhizae 12g；The medicine that the present invention is provided is a Chinese prescription treated both principal and secondary aspect of disease.

Description

It is a kind of to treat decoction medicine of Severe Acute Pancreatitis SAP and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of decoction medicine for treating Severe Acute Pancreatitis SAP, especially It is the field of the decoction medicine that is used for severe acute pancreatitis and preparation method thereof.

Background technology

Doctor thinks：Severe Acute Pancreatitis SAP（SAP）Belong to the specific type of acute pancreatitis, be one kind be dangerously ill, The acute abdomen that complication is more, case fatality rate is higher, accounts for the 10%~20% of whole acute pancreatitis.Last century the eighties, most diseases Example dies from disease early stage, until nearly ten years, with the progress of SAP surgical interventions, cure rate increases, but overall mortality rate Still it is up to 17% or so.70%~80% Severe Acute Pancreatitis SAP is due to disease of biliary tract, indulges in excessive drinking and eats and drinks immoderately caused.

So, with regard to how to find it is a kind of can effectively treat the Chinese medicine composition of Severe Acute Pancreatitis SAP, be art technology The problem of personnel are urgently to be resolved.

The content of the invention

With continuing to develop for China's traditional Chinese medicine, on treatment Severe Acute Pancreatitis SAP, people gradually appreciate The advantage of Chinese traditional treatment Severe Acute Pancreatitis SAP, and the advantage, pin such as good effect, instant effect, toxic side effect be small over the course for the treatment of To the present situation of existing western medical treatment Severe Acute Pancreatitis SAP, the purpose of the present invention is to be that providing one kind treats severe acute pancreas Scorching decoction medicine, to solve the problem of severe acute pancreatitis is got well early.The medicine is with common Chinese medicine For raw material, by selecting rational medicine and mass parts ratio, above-mentioned Severe Acute Pancreatitis SAP can be effectively treated.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats severe acute pancreas Decoction medicine of adenositis and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows：

6~18g of oriental wormwood, 10~18g of Glabrous Sarcandra Herb, 10~18g of giant knotweed, 10~35g of rhizoma imperatae, 6~12g of linseed, corydalis tuber 8~ 18g, 15~65g of desmodium, 3~12g of radix bupleuri, 5~18g of radix scutellariae, 4~12g of Chinese herbaceous peony, 3~9g of the tuber of pinellia, 8~18g of the red sage root, ginger 3 ~12g, 9~16g of jujube, 3~15g of rheum officinale, cape jasmine（Fry）10~25g, 8~18g of saltcake, 3~12g of the dried immature fruit of citron orange, 3~12g of the bark of official magnolia, 2.5~7.5g of the root of gansui, 3~15g of radix glycyrrhizae.

It is a kind of to treat decoction medicine of Severe Acute Pancreatitis SAP and preparation method thereof, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

8~16g of oriental wormwood, 11~16g of Glabrous Sarcandra Herb, 11~16g of giant knotweed, 11~31g of rhizoma imperatae, 8~11g of linseed, corydalis tuber 10 ~16g, 18~58g of desmodium, 5~11g of radix bupleuri, 8~16g of radix scutellariae, 6~11g of Chinese herbaceous peony, 5~8g of the tuber of pinellia, 10~16g of the red sage root, life 5~11g of ginger, 10~14g of jujube, 6~13g of rheum officinale, cape jasmine（Fry）12~22g, 10~16g of saltcake, 6~11g of the dried immature fruit of citron orange, the bark of official magnolia 5 ~11g, 3~7g of the root of gansui, 6~13g of radix glycyrrhizae.

It is a kind of to treat decoction medicine of Severe Acute Pancreatitis SAP and preparation method thereof, it is characterised in that " the optimal side Each component and its mass parts of the medicine of case " are than as follows：

Oriental wormwood 14g, Glabrous Sarcandra Herb 14g, giant knotweed 14g, rhizoma imperatae 28g, linseed 10g, corydalis tuber 14g, desmodium 50g, radix bupleuri 10g, radix scutellariae 14g, Chinese herbaceous peony 10g, tuber of pinellia 7g, red sage root 14g, ginger 10g, jujube 13g, rheum officinale 12g, cape jasmine（Fry）20g, saltcake 14g, dried immature fruit of citron orange 10g, bark of official magnolia 10g, root of gansui 6g, radix glycyrrhizae 12g.

It is a kind of to treat decoction medicine of Severe Acute Pancreatitis SAP and preparation method thereof, it is characterised in that methods described includes Following steps are prepared from：

A, above-mentioned raw materials Chinese medicine picked after impurity and dust, being respectively crushed into coarse according to mass parts ratio decocts a drug wrapped；

B, the raw material Chinese medicine wrapped is put into cold boiling water and soaks half an hour, then again by soaked medicine and immersion medicine The clarified solution of thing is put into marmite in the lump, and the cold boiling water for injecting medicine 60mm decoct 45 minutes for the first time, after leaching decoction, The tepor boiling water for re-injecting medicine 56mm carries out second of decoction 35 minutes, and secondary mixing is condensed into 50% milli of Chinese medicine liquid 540 Rise standby.

It is a kind of to treat decoction medicine of Severe Acute Pancreatitis SAP and preparation method thereof, it is characterised in that the instructions of taking For：The Chinese medicine liquid prepared was taken with one day, once a dose in the morning, afternoon and evening, milliliter/time of dosage 180 is taken advantage of and warmly taken, medication 8~ After 16 days, sign is alleviated, and amylase in urine recovers normal, and disease accuses recovery from illness.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Oriental wormwood, nature and flavor：It is bitter, pungent, be slightly cold, the effect of with clearing away damp-heat, removing jaundice subcutaneous ulcer, for treating jaundice oliguria, wet sore itch, passing Metachromia icteric hepatitis；

Glabrous Sarcandra Herb, nature and flavor：It is bitter, pungent, flat, with dispelling wind and eliminating dampness, promoting blood circulation to remove blood stasis, it is clearing heat and detoxicating the effect of, for treat limbs fiber crops Wood, traumatic injury, fracture, dysmenorrhes, postpartum stasis of blood, pneumonia, striving property appendicitis, acute gastroenteritis, bacillary dysentery, gall-bladder Inflammation, abscess, stomatitis, arthralgia pain due to rheumatism；

Giant knotweed, nature and flavor：Bitter, acid, cold nature, the effect of with promoting blood circulation to remove blood stasis, dispelling wind and removing obstruction in the meridians, clearing heat and promoting diuresis, removing toxic substances, for treating Under women's Amenorrhea, dysmenorrhoea, lochiostasis, lumps in the chest and abdomen, injury from falling down, arthralgia pain due to rheumatism, jaundice with damp-heat pathogen, stranguria with turbid discharge band, sore Pyogenic infections, venomous snake bite, scald；

Rhizoma imperatae, nature and flavor：It is sweet；It is cold, the effect of with cooling blood and hemostasis, clearing heat and promoting fluid, inducing diuresis for treating strangurtia, for treat blood-head bleeding, Pyreticosis polydipsia, stomach energy are vomitted the diseases such as the puckery pain of inverse, dyspnea and cough due to lung-heat, dribbling urination, oedema, jaundice；

Linseed, nature and flavor：It is sweet, mild-natured, the effect of with nourishing the blood to expel wind, moistening dryness for relaxing bowels, for treat leprosy, dry skin, Itch, alopecia, sore eczema, dry constipation of intestines；

Corydalis tuber, nature and flavor：Acrid, bitter, warm, it is nontoxic, with promoting blood circulation, the effect of stasis of blood, qi-regulating, analgesic is dissipated, for treating trusted subordinate's waist and knee All pains, irregular menstruation, abdominal mass, metrorrhagia, postpartum anemic fainting, lochiorrhagia, traumatic injury；

Desmodium, nature and flavor：It is sweet, slight bitter, cool in nature, the effect of with promoting diuresis for stranguria, clearing heat and detoxicating, eliminating stasis to subdue swelling, for treating liver Courage and stone in urinary system, heat gonorrhea, nephritic dropsy, jaundice with damp-heat pathogen, sore carbuncle swells, venomous snake bite, traumatic injury；

Radix bupleuri, nature and flavor：Pungent, cold nature, brought down a fever with inducing diaphoresis, soothing liver-qi stagnation, rise lift yang-energy the effect of, for treat diseases caused by external factors hair Under heat, fevers and chills alternate, malaria, liver-depressed hypochondrium pain mammary swelling, a headache dizzy, irregular menstruation, the prolapse of the anus of collapse from qi deficiency, the prolapse of uterus, stomach Hang down and wait disease；

Radix scutellariae, nature and flavor：It is bitter, cold in nature, with clearing heat-fire, eliminating dampness removing toxic substances, hemostasis, it is antiabortive the effect of, coughed for treating lung heat Cough, the headache of high fever apoplexy coma due to blocking of the respiratory system shies epilepsy, irascibility, red eye, swell pain, jaundice with damp-heat pathogen, rush down dysentery, heat gonorrhea, hematemesis blood, uterine bleeding, fetal movement with fever, carbuncle Swollen furunculosis；

Chinese herbaceous peony, nature and flavor：It is bitter, be slightly cold, the effect of with clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down；

The tuber of pinellia, nature and flavor：It is pungent, warm-natured, it is poisonous, the effect of with eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, coughed for treating Breathe heavily abundant expectoration, vomiting gastric disorder causing nausea, feeling of oppression and fullness in the chest and epigastrium dizziness of having a headache, uneasy sleeping at night, gall subcutaneous nodule, swollen ulcer drug；

The red sage root, nature and flavor：Bitter, cold nature, the effect of with promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, are used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, a lump in the abdomen causing distension and pain, hot numbness swells and ache, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

Ginger, nature and flavor：It is pungent, warm-natured, the effect of with expelling cold and relieving exterior syndrome, stopping nausea and vomiting by lowering the adverse flow of QI, preventing phlegm from forming and stopping coughing, for treating chill sense Emit, fever with aversion to cold, headache nasal obstruction, vomiting, sputum cough, turgor, the disease such as diarrhea；

Jujube, nature and flavor：Sweet, temperature, with tonifying spleen and stomach, replenishing qi and blood, tranquilizing mind, adjusts Ying Wei and the effect of the property of medicine, for treating taste The disease such as weakness, insufficiency of vital energy and blood, anorexia and loose stool, lassitude hypodynamia, palpitation and insomnia, hysteria of womam, disharmony between ying and wei；

Rheum officinale, nature and flavor：It is bitter, cold in nature, with the effect of stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis, removing toxic substances is attacked, for treating reality Hot constipation, the thermojunction feeling of stuffiness in chest, damp-heat dysentery, jaundice, gonorrhoea, oedema abdomen full, difficult urination, hot eyes, abscess of throat, aphthae, Gastropyretic vomiting, haematemesis, spitting of blood, bleeding from five sense organs or subcutaneous tissue, have blood in stool, hematuria, store blood, Amenorrhea, postpartum stasis of blood, lumps in the chest and abdomen, traumatic injury, heat Malicious large carbuncle, erysipelas, scald wind；

Cape jasmine（Fry）, nature and flavor：It is bitter, cold, the effect of with heat-clearing, purging intense heat, cool blood, for treating pyreticosis restlessness of asrhenia type and insomnia, jaundice, pouring Disease, quench one's thirst, hot eyes, pharyngalgia, haematemesis, bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, pathopyretic ulcer, sprain and swell and ache；

Saltcake, nature and flavor：It is pungent, bitter, salty, cold, with purging heat, moisturize, softening hard masses the effect of, for treat stagnant real heat, abdominal distention constipation, Stop phlegm accumulation, mouth it is red hide from view, the disease such as erysipelas, carbuncle swells；

The dried immature fruit of citron orange, nature and flavor：Bitter, acrid, cold, with relieving stagnant Qi disperse accumulations, resolving sputum remove ruffian the effect of, for treat internal stagnation, feeling of fullness distending pain, The diseases such as constipation, weight after rush down dysentery, accumulation of pathogens in chest, gastroptosis, the prolapse of uterus, prolapse of the anus；

The bark of official magnolia, nature and flavor：It is bitter, pungent, warm-natured, the effect of with gas consumption product, eliminating dampness except full, relieving asthma, for treating dyspepsia gas Stagnant, abdominal distention constipation, damp retention in middle-jiao, abdominal swelling and diarrhea, phlegm stops up the circulation of vital energy in the wrong direction, chest full of cough；

The root of gansui, nature and flavor：It is bitter, cold, it is poisonous, the effect of with removing water retention by purgation, for treating oedema turgor, chest and abdomen ponding, phlegm and retained fluid product The poly-, circulation of vital energy in the wrong direction is breathed with cough, difficulty in urination and defecation；

Radix glycyrrhizae, nature and flavor：It is sweet, flat, with invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swollen in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swell and ache, infant fetal toxin and medicine, food poisoning.

Medicine of the present invention is the principle based on Chinese traditional treatment Severe Acute Pancreatitis SAP, from the disease according to Severe Acute Pancreatitis SAP Reason mechanism and pharmacological action are thought：With regard to Severe Acute Pancreatitis SAP, each raw material herbal medicine efficacy in medicine provided by the present invention is total to Play, have good therapeutic effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned Severe Acute Pancreatitis SAP, using the formula The medicine effect of preparation is good, instant effect, is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to this The embodiment of invention is described in further detail：

Embodiment 1：

A kind of decoction medicine for treating Severe Acute Pancreatitis SAP, it is characterised in that each component and its mass parts of the medicine Than as follows：

Oriental wormwood 14g, Glabrous Sarcandra Herb 14g, giant knotweed 14g, rhizoma imperatae 28g, linseed 10g, corydalis tuber 14g, desmodium 50g, radix bupleuri 10g, radix scutellariae 14g, Chinese herbaceous peony 10g, tuber of pinellia 7g, red sage root 14g, ginger 10g, jujube 13g, rheum officinale 12g, cape jasmine（Fry）20g, saltcake 14g, dried immature fruit of citron orange 10g, bark of official magnolia 10g, root of gansui 6g, radix glycyrrhizae 12g.

Embodiment 2：

A kind of decoction medicine for treating Severe Acute Pancreatitis SAP, it is characterised in that each component and its mass parts of the medicine Than as follows：

Oriental wormwood 16g, Glabrous Sarcandra Herb 16g, giant knotweed 16g, rhizoma imperatae 31g, linseed 11g, corydalis tuber 16g, desmodium 58g, radix bupleuri 11g, radix scutellariae 16g, Chinese herbaceous peony 11g, tuber of pinellia 8g, red sage root 16g, ginger 11g, jujube 14g, rheum officinale 13g, cape jasmine（Fry）22g, saltcake 16g, dried immature fruit of citron orange 11g, bark of official magnolia 11g, root of gansui 7g, radix glycyrrhizae 13g.

Embodiment 3：

A kind of decoction medicine for treating Severe Acute Pancreatitis SAP, it is characterised in that each component and its mass parts of the medicine Than as follows：

Oriental wormwood 18g, Glabrous Sarcandra Herb 18g, giant knotweed 18g, rhizoma imperatae 35g, linseed 12g, corydalis tuber 18g, desmodium 65g, radix bupleuri 12g, radix scutellariae 18g, Chinese herbaceous peony 12g, tuber of pinellia 9g, red sage root 18g, ginger 12g, jujube 16g, rheum officinale 15g, cape jasmine（Fry）25g, saltcake 18g, dried immature fruit of citron orange 12g, bark of official magnolia 12g, root of gansui 7.5g, radix glycyrrhizae 15g.

Model case

Through clinical conditions severe acute pancreatitis totally 2480, the age is 1450 of more than 62 years old, only 1030 Example is less than 62 years old.2240 fully recovered in 2480 patients, effective 240, total effective rate is up to 100%.

Claims (3)

1. a kind of decoction medicine for treating Severe Acute Pancreatitis SAP, it is characterised in that each component and its quality of the medicine Part is than as follows：

6~18g of oriental wormwood, 10~18g of Glabrous Sarcandra Herb, 10~18g of giant knotweed, 10~35g of rhizoma imperatae, 6~12g of linseed, corydalis tuber 8~ 18g, 15~65g of desmodium, 3~12g of radix bupleuri, 5~18g of radix scutellariae, 4~12g of Chinese herbaceous peony, 3~9g of the tuber of pinellia, 8~18g of the red sage root, ginger 3 ~12g, 9~16g of jujube, 3~15g of rheum officinale, cape jasmine（Fry）10~25g, 8~18g of saltcake, 3~12g of the dried immature fruit of citron orange, 3~12g of the bark of official magnolia, 2.5~7.5g of the root of gansui, 3~15g of radix glycyrrhizae.

2. it is according to claim 1 treatment Severe Acute Pancreatitis SAP decoction medicine, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

8~16g of oriental wormwood, 11~16g of Glabrous Sarcandra Herb, 11~16g of giant knotweed, 11~31g of rhizoma imperatae, 8~11g of linseed, corydalis tuber 10 ~16g, 18~58g of desmodium, 5~11g of radix bupleuri, 8~16g of radix scutellariae, 6~11g of Chinese herbaceous peony, 5~8g of the tuber of pinellia, 10~16g of the red sage root, life 5~11g of ginger, 10~14g of jujube, 6~13g of rheum officinale, cape jasmine（Fry）12~22g, 10~16g of saltcake, 6~11g of the dried immature fruit of citron orange, the bark of official magnolia 5 ~11g, 3~7g of the root of gansui, 6~13g of radix glycyrrhizae.

3. the decoction medicine of the treatment Severe Acute Pancreatitis SAP according to claim 1 to 2, it is characterised in that the medicine Each component and its mass parts than as follows：

Oriental wormwood 14g, Glabrous Sarcandra Herb 14g, giant knotweed 14g, rhizoma imperatae 28g, linseed 10g, corydalis tuber 14g, desmodium 50g, radix bupleuri 10g, radix scutellariae 14g, Chinese herbaceous peony 10g, tuber of pinellia 7g, red sage root 14g, ginger 10g, jujube 13g, rheum officinale 12g, cape jasmine（Fry）20g, saltcake 14g, dried immature fruit of citron orange 10g, bark of official magnolia 10g, root of gansui 6g, radix glycyrrhizae 12g.