CN107233230A - One kind, which is releived, neutralizes cosmetic composition and preparation method thereof - Google Patents
One kind, which is releived, neutralizes cosmetic composition and preparation method thereof Download PDFInfo
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- CN107233230A CN107233230A CN201710608946.XA CN201710608946A CN107233230A CN 107233230 A CN107233230 A CN 107233230A CN 201710608946 A CN201710608946 A CN 201710608946A CN 107233230 A CN107233230 A CN 107233230A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
Releived the present invention relates to one kind and neutralize cosmetic composition and preparation method thereof, neutralization cosmetic composition of releiving is made up of raw materials such as protease, protease Dextran conjugates, plant amino acid and sodium dihydrogen phosphates, and preparation method includes heating, emulsification, cooling, the process being redissolved.Beneficial effects of the present invention are：The neutralization cosmetic composition of releiving of the present invention, which has, pins moisture；Skin ph is neutralized, makes skin flexible and glossiness；The amino acid of needed by human body is supplemented, makes the features such as skin is soft glossy.
Description
Technical field
The invention belongs to technological field of biochemistry, and in particular to one kind, which is releived, neutralizes cosmetic composition and its preparation side
Method.
Background technology
Cosmetic spray is exactly to be ejected liquid with imperceptible water particle using high-pressure system, and these are small artificial
In atmosphere, so as to form the vaporific wonder of white, pole is said as the effect of natural fog for mist particle energy long time drift, suspension
Spraying.Many women prefer to use spraying, because it only needs finger to gently press, either moisturizing, fragrance, it is sun-proof, go acne, it is or easypro
It is slow calm, it is beautiful simple.Spraying by face, with spray, the fine globule forms silkiness diaphragm on skin,
The injury of extraneous sunlight and pollution to skin is also isolated while bringing soft and moist pleasant skin care to maintain.But, spray water
It is short in the time that skin is stayed, and the moisture of skin surface can be also taken away when it volatilizees, cause skin surface to dry, lose
Water.
The content of the invention
In order to solve the problem of prior art is present, releived the invention provides one kind and neutralize cosmetic composition and its system
Preparation Method, it, which has, pins moisture；Skin ph is neutralized, makes skin flexible and glossiness；The amino acid of needed by human body is supplemented,
Make the features such as skin is soft glossy.
Releived neutralization cosmetic composition it is an object of the invention to provide one kind.
According to the neutralization cosmetic composition of releiving of the embodiment of the present invention, its neutralization cosmetic combinations of releiving
Thing：
Lauroyl collagen amino acid sodium 2.5-3.5%；Protease 4.8-5.2%；Protease-Dextran conjugates 1.7-
2.3%；Plant amino acid 7.5-8.5%；Sodium dihydrogen phosphate 0.08-0.12%；Disodium hydrogen phosphate 0.08-0.12%；Hydrolysis is saturating
The sour sodium 0.1-0.3% of bright matter；Water adds to 100%.
According to the neutralization cosmetic composition of releiving of the embodiment of the present invention, wherein, the neutralization of releiving is made up
Product composition is further releived neutralization cosmetic composition：
Lauroyl collagen amino acid sodium 3.0%；Protease 5.0%；Protease-Dextran conjugates 2.0%；Plant ammonia
Base acid 8.0%；Sodium dihydrogen phosphate 0.1%；Disodium hydrogen phosphate 0.1%；Hydrolyze Sodium Hyaluronate 0.2%；Water adds to 100%.
According to the neutralization spraying of releiving of the embodiment of the present invention, wherein, the plant amino acid is glycine betaine.Sweet tea
Dish alkali is the amino acid extracted from beet.
According to the neutralization spraying of releiving of the embodiment of the present invention, wherein, the protease is trypsase.
It is preferred that, the protease is hydrolysising protease.It is main with Esperase (Japan, Nouo Norudics on the market
Company), trypsase (U.S., Sigma companies), chymotrypsin (U.S., Sigma companies) etc..
Protease is the general name of the class of enzymes of aminosal peptide chain.It is divided into endopeptidase and end in the way of it degrades polypeptide
The class of peptase two.The former can cut off the polypeptide chain of macromolecule from centre, form the less protein of molecular weight and peptone；The latter can divide again
For carboxypeptidase and aminopeptidase, peptide chain is hydrolyzed generate respectively by they one by one from the free carboxy termini or free amine end of polypeptide
Amino acid.By the optimum pH of its reaction, it is divided into acid protease, neutral proteinase and alkali protease.Should in industrial production
Protease, mainly endopeptidase.Polyembryony protease is the germ protein enzyme of various plants.Be one kind can by plant not
The germ protein being easily absorbed and used, is fully converted into the efficient enzyme of the essential amino acid being easily absorbed and used of high-quality.
The enzyme applied in cosmetics needs to meet three requirements：One is that under usual holding conditions, the stability of enzyme is necessary
Meet the requirement of business shelf life；Two be that the activity of enzyme can not be suppressed by cosmetic formulations composition；Three be that enzyme is not when smearing
Toxicity can be produced.
Seldom, enzyme is product obtained by after certain fermentation of materials to currently commercially enzyme-added skin care item.Because enzyme is in formula
In stability it is not high, but also there are potential allergic effect sensitisation problems.
Protease glucan is also referred to as glucan-protease conjugate, and glucan is introduced using hydrogen bromide or cyanurate acid anhydride etc.
Functional group, the functional group is reacted with the amino of enzyme, and covalent bond is formed between glucan and enzyme.Protease glucan is more steady
It is fixed, there is good stability under usual holding conditions.Face cleaning effect after protease glucan is added in cosmetics good, and protease
Glucan has no toxic side effect.
Amino acid is the general designation of the class organic compound containing amino and carboxyl, the base of biological function macro-molecular protein
This composition unit.Amino acid can be synthesized in plant or animal tissue, can be obtained by protein hydrolysis, in being metabolized of tissue, raw
Played an important role in long, maintenance and repair process.Amino acid is to constitute one of basic masonry of life mansion.Plant amino acid is
Refer to the amino acid synthesized in plant, there is protease hydrolytic vegetable protein to obtain.Plant amino acid more pro-skin, can be skin
Amino acid needed for providing, absorbs more preferable.
Sodium Hyaluronate is one of composition of human body skin in itself, is that the acid glutinous sugar of most wide one kind is distributed in human body, deposits
It is in the matrix of connective tissue, with good moisture-keeping function.Sodium Hyaluronate, using more, there is guarantor in cosmetic field
Wet effect, is the material extracted from cockscomb, and can also be fermented by Lactococcus is made, and is white or off-white color particle or powder
End, odorless, when drying, nitrogen content is 2.8%-4.0%, and glucuronic acid content is 37.0%-51.0%.Used in the present invention
Hydrolysis Sodium Hyaluronate be to be obtained from cockscomb reclaimed water solution, there is more preferable guarantor than the obtained Sodium Hyaluronate of Lactococcus fermentation
Wet effect.
Another object of the present invention is to provide above-mentioned releive and neutralizes the preparation method of cosmetic composition,
Comprise the following steps：
(1) water is weighed into emulsification pot by proportioning, carries out being stirred and heated to 80-90 DEG C for the first time, be incubated 10-
Lauroyl collagen amino acid sodium, sodium dihydrogen phosphate, disodium hydrogen phosphate, hydrolysis Sodium Hyaluronate are added after 50 minutes, is stirred to molten
Solve and be well mixed, cool, obtain first time mixture；In temperature-rise period, stirring power is heated evenly water；
(2) when the first time mixture temperature is down to 30-50 DEG C, protease, protease glucan, plant ammonia are added
Base is sour, carries out second of stirring to being completely dissolved, after being uniformly dispersed, and neutralization cosmetic of releiving can be obtained by being cooled to less than 30 DEG C
Product composition.
The preparation method of cosmetic composition is neutralized according to releiving for the embodiment of the present invention, further comprised,
It is 85 DEG C that temperature is heated to described in step (1), and the soaking time is 30 minutes.
Further, stirring for the first time described in step (1) is stirred under pressure, and the pressure of the stirred under pressure is 70MPa,
The speed of the first time stirring is 1200 revs/min, and the time of the first time stirring is 20 minutes.
Further, the speed of second of stirring described in step (2) is 1200 revs/min, second of stirring
Time is 25 minutes；The homogenizer for being uniformly dispersed the use of pressure to be 70MPa is to the mixture after second of stirring
Pressurization homogenization 2-3 times, it is each 20-40 minutes, it is well mixed to the mixture.
Further, first by the protease, protease glucan, plant ammonia before being stirred for the second time described in step (2)
Base acid is dissolved with water.
Further, the solution temperature is 20-30 DEG C.
Lauroyl collagen amino acid sodium is amino acid surfactant, and function is foaming, cleaning.
Beneficial effects of the present invention are：The neutralization cosmetic composition of releiving of the present invention is in order to ensure the quality of finished product, greatly
Courage uses protease, proteglycan enzyme and hydrolysis Sodium Hyaluronate for raw material, then and in order to keep the stability of finished product to pass through
The multiple research crossed finds there is preferable stability using finished product made from the raw material and preparation method of the present invention, and has
And skin ph value, make skin flexible and glossiness；Supplement the amino acid of needed by human body, the spy for making skin soft, glossy
Point.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below
Detailed description.Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are resulting on the premise of creative work is not made to be owned
Other embodiment, belongs to the scope that the present invention is protected.
Embodiment 1
Releive neutralization cosmetic composition, it includes：
Lauroyl collagen amino acid sodium 2.5wt%；Papain 5.0wt%；Protease-Dextran conjugates
2.0wt%；Glycine betaine 8.0wt%；Sodium dihydrogen phosphate 0.1wt%；Disodium hydrogen phosphate 0.1wt%；Hydrolyze Sodium Hyaluronate
0.2wt%；Water adds to 100wt%.
Papain, also known as papain, are a kind of proteolytic enzymes.Papain is the one kind contained in papaya
Low specificity proteolytic enzyme, universally present in the root of papaya, stem, leaf and fruit, wherein in immature milk
Content is most abundant.The activated centre of papain contains cysteine, belongs to thiol protease, it has enzyme activity high, thermally-stabilised
Property it is good, natural safe and healthy the features such as, therefore obtain in industries such as food, medicine, feed, daily use chemicals, leather and weavings extensively should
With.
Protease is the general name of the class of enzymes of aminosal peptide chain.It is divided into endopeptidase and end in the way of it degrades polypeptide
The class of peptase two.The former can cut off the polypeptide chain of macromolecule from centre, form the less protein of molecular weight and peptone；The latter can divide again
For carboxypeptidase and aminopeptidase, peptide chain is hydrolyzed generate respectively by they one by one from the free carboxy termini or free amine end of polypeptide
Amino acid.By the optimum pH of its reaction, it is divided into acid protease, neutral proteinase and alkali protease.Should in industrial production
Protease, mainly endopeptidase.
Lauroyl collagen amino acid sodium is amino acid surfactant, and function is foaming, cleaning.
Preparation method, comprises the following steps：
(1) water is weighed into emulsification pot by proportioning, carries out being stirred and heated to 85 DEG C for the first time, be incubated 30 minutes
Add lauroyl collagen amino acid sodium, sodium dihydrogen phosphate, disodium hydrogen phosphate, hydrolysis Sodium Hyaluronate afterwards, stirring is to dissolving and mix
Close uniform, cooling obtains first time mixture；
(2) when the first time mixture temperature is down to 40 DEG C, papain, protease glucan, beet are added
Alkali, carries out second of stirring to being completely dissolved, after being uniformly dispersed, neutralization cosmetic combinations of releiving can be obtained by being cooled to 20 DEG C
Thing.
Embodiment 2
Releive neutralization cosmetic composition, it includes：
Lauroyl collagen amino acid sodium 3.5wt%；Polyembryony protease 4.8wt%；Protease-Dextran conjugates
1.7wt%；Glycine betaine 8.5wt%；Sodium dihydrogen phosphate 0.12wt%；Disodium hydrogen phosphate 0.12wt%；Hydrolyze Sodium Hyaluronate
0.1wt%；Deionized water adds to 100wt%.
Polyembryony protease is the germ protein enzyme of various plants.It is a kind of the embryo that is absorbed and used can will to be difficult in plant
Bud albumen, is fully converted into the efficient enzyme of the essential amino acid being easily absorbed and used of high-quality.
Preparation method, comprises the following steps：
(1) water is weighed into emulsification pot by proportioning, carries out 70MPa stirred under pressure, the speed of stirring is 1200
Rev/min, 80 DEG C are heated to while stirring, and the time of stirring is 20 minutes, and insulation adds lauroyl collagenous amino after 10 minutes
Sour sodium, sodium dihydrogen phosphate, disodium hydrogen phosphate, hydrolysis Sodium Hyaluronate, stirring cool to dissolving and being well mixed, obtain first
Secondary mixture；
(2) first the protease, protease glucan, glycine betaine are dissolved to form lysate with 20 DEG C of water, treats described
When first time mixture temperature is down to 50 DEG C, protease, protease glucan, the lysate of glycine betaine are added, is carried out second
Stirring is to being completely dissolved, and the speed of stirring is 1200 revs/min, and the time of stirring is 25 minutes, the use of pressure is the equal of 70MPa
Matter machine stirred to described second after mixture pressurization homogenization 3 times, 20 minutes every time, after being uniformly dispersed to the mixture,
It is cooled to 28 DEG C and obtains neutralization cosmetic composition of releiving.
Embodiment 3
Releive neutralization cosmetic composition, it includes：
Lauroyl collagen amino acid sodium 3.0wt%；Polyembryony protease 5.2wt%；Protease-Dextran conjugates
2.3wt%；Glycine betaine 7.5wt%；Sodium dihydrogen phosphate 0.08wt%；Disodium hydrogen phosphate 0.08wt%；Hydrolyze Sodium Hyaluronate
0.3wt%；Deionized water adds to 100wt%.
Polyembryony protease is the germ protein enzyme of various plants.It is a kind of the embryo that is absorbed and used can will to be difficult in plant
Bud albumen, is fully converted into the efficient enzyme of the essential amino acid being easily absorbed and used of high-quality.
Preparation method, comprises the following steps：
(1) water is weighed into emulsification pot by proportioning, the speed for carrying out 70MPa stirred under pressure stirring is 1200
Rev/min, 90 DEG C are heated to while stirring, and the time of stirring is 20 minutes, and insulation adds lauroyl collagenous amino after 50 minutes
Sour sodium, sodium dihydrogen phosphate, disodium hydrogen phosphate, hydrolysis Sodium Hyaluronate, stirring cool to dissolving and being well mixed, obtain first
Secondary mixture；
(2) first the protease, protease glucan, glycine betaine are dissolved to form lysate with 30 DEG C of water, treats described
When first time mixture temperature is down to 30 DEG C, protease, protease glucan, the lysate of glycine betaine are added, is carried out second
Stirring is to being completely dissolved, and the speed of stirring is 1200 revs/min, and the time of stirring is 25 minutes, the use of pressure is the equal of 70MPa
Matter machine stirred to described second after mixture pressurization homogenization 2 times, 20 minutes every time, after mixture is uniformly dispersed, be cooled to
30 DEG C can obtain neutralization cosmetic composition of releiving.
Embodiment 4
Releive neutralization cosmetic composition, it includes：
Lauroyl collagen amino acid sodium 3.0wt%；Trypsase 5.2wt%；Protease-Dextran conjugates
2.3wt%；Glycine betaine 7.5wt%；Sodium dihydrogen phosphate 0.08wt%；Disodium hydrogen phosphate 0.08wt%；Hydrolyze Sodium Hyaluronate
0.3wt%；Deionized water adds to 100wt%.
Preparation method, comprises the following steps：
(1) water is weighed into emulsification pot by proportioning, the speed for carrying out 70MPa stirred under pressure stirring is 1000
Rev/min, 85 DEG C are heated to while stirring, and the time of stirring is 25 minutes, and insulation adds lauroyl collagenous amino after 50 minutes
Sour sodium, sodium dihydrogen phosphate, disodium hydrogen phosphate, hydrolysis Sodium Hyaluronate, stirring cool to dissolving and being well mixed, obtain first
Secondary mixture；
(2) first the trypsase, protease glucan, glycine betaine are dissolved to form lysate with 45 DEG C of water, treats institute
When stating first time mixture temperature and being down to 45 DEG C, trypsase, protease glucan, the lysate of glycine betaine are added, the is carried out
Secondary agitation is to being completely dissolved, and the speed of stirring is 1200 revs/min, and the time of stirring is 30 minutes, the use of pressure is 70MPa
Homogenizer stirred to described second after mixture pressurization homogenization 3 times, 25 minutes every time, after mixture is uniformly dispersed, drop
Temperature can obtain neutralization cosmetic composition of releiving to 25 DEG C.
The neutralization cosmetic composition of releiving of the present invention especially courageously uses to keep the stability and practicality of finished product
Protease, proteglycan enzyme and hydrolysis Sodium Hyaluronate are raw material, with skin ph is neutralized, make skin flexible and gloss
Degree；Supplement needed by human body amino acid, make skin it is soft, it is glossy the characteristics of.
The foregoing is only a specific embodiment of the invention, but protection scope of the present invention is not limited thereto, any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all be contained
Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
- The neutralization cosmetic composition 1. one kind is releived, it is characterised in that the neutralization cosmetic composition of releiving include it is following by According to the component of mass percentage：Lauroyl collagen amino acid sodium 2.5-3.5%；Protease 4.8-5.2%；Protease-Dextran conjugates 1.7-2.3%； Plant amino acid 7.5-8.5%；Sodium dihydrogen phosphate 0.08-0.12%；Disodium hydrogen phosphate 0.08-0.12%；Hydrolyze hyaluronic acid Sodium 0.1-0.3%；Water adds to 100%.
- 2. neutralization cosmetic composition according to claim 1 of releiving, it is characterised in that the neutralization cosmetics group of releiving Compound includes the following component according to mass percentage：Lauroyl collagen amino acid sodium 3.0%；Protease 5.0%；Protease-Dextran conjugates 2.0%；Plant amino acid 8.0%；Sodium dihydrogen phosphate 0.1%；Disodium hydrogen phosphate 0.1%；Hydrolyze Sodium Hyaluronate 0.2%；Water adds to 100%.
- 3. neutralization cosmetic composition according to claim 1 of releiving, it is characterised in that the plant amino acid is beet Alkali.
- 4. neutralization cosmetic composition according to claim 1 of releiving, it is characterised in that the protease is tryptose Enzyme.
- 5. releiving according to any one of Claims 1-4 neutralizes the preparation method of cosmetic composition, it is characterised in that Comprise the following steps：(1) water is weighed into emulsification pot by proportioning, carries out being stirred and heated to 80-90 DEG C, 10-50 points of insulation for the first time Lauroyl collagen amino acid sodium, sodium dihydrogen phosphate, disodium hydrogen phosphate, hydrolysis Sodium Hyaluronate are added after clock, stirring to dissolving is simultaneously Well mixed, cooling obtains first time mixture；(2) when the first time mixture temperature is down to 30-50 DEG C, protease, protease glucan, plant amino are added Acid, carries out second of stirring to being completely dissolved, after being uniformly dispersed, neutralization cosmetics of releiving can be obtained by being cooled to less than 30 DEG C Composition.
- 6. according to claim 5 releive neutralizes the preparation method of cosmetic composition, it is characterised in that in step (1) The temperature that is heated to is 85 DEG C, and the soaking time is 30 minutes.
- 7. according to claim 5 releive neutralizes the preparation method of cosmetic composition, it is characterised in that in step (1) The first time stirring is stirred under pressure, and the pressure of the stirred under pressure is 70MPa, and the speed of the first time stirring is 1200 Rev/min, the time of the first time stirring is 20 minutes.
- 8. according to claim 5 releive neutralizes the preparation method of cosmetic composition, it is characterised in that in step (2) The speed of second of stirring is 1200 revs/min, and the time of second of stirring is 25 minutes；It is described be uniformly dispersed for Mixture pressurization homogenization after being stirred using pressure for 70MPa homogenizer to described second 2-3 times, it is each 20-40 minutes, It is well mixed to the mixture.
- 9. according to claim 5 releive neutralizes the preparation method of cosmetic composition, it is characterised in that in step (2) First the protease, protease glucan, plant amino acid water are dissolved before second of stirring.
- 10. according to claim 9 releive neutralizes the preparation method of cosmetic composition, it is characterised in that the dissolving Temperature is 20-30 DEG C.
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| CN201710608946.XA CN107233230A (en) | 2017-07-24 | 2017-07-24 | One kind, which is releived, neutralizes cosmetic composition and preparation method thereof |
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| CN201710608946.XA CN107233230A (en) | 2017-07-24 | 2017-07-24 | One kind, which is releived, neutralizes cosmetic composition and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102652722A (en) * | 2011-03-03 | 2012-09-05 | 成都宇泽生物基因化妆品有限公司 | Moisturizing cream containing rose essence |
| CN102670459A (en) * | 2012-06-06 | 2012-09-19 | 桑达化工（南通）有限公司 | Anti-winkle lotion |
| CN104546603A (en) * | 2014-12-24 | 2015-04-29 | 陕西艾尔肤组织工程有限公司 | Composition with calming and relieving functions and preparation method thereof |
| CN105616325A (en) * | 2016-01-30 | 2016-06-01 | 海南京润珍珠生物技术股份有限公司 | Nacre-based tightening and moisturizing facial mask and manufacturing method thereof |
| CN106176452A (en) * | 2016-08-27 | 2016-12-07 | 朱耀灯 | A kind of deep water supplement moisturizing facial milk cleanser |
| CN106619274A (en) * | 2016-11-08 | 2017-05-10 | 宁夏艾伊生物工程研发有限公司 | Moisturizer and preparation method thereof |
-
2017
- 2017-07-24 CN CN201710608946.XA patent/CN107233230A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102652722A (en) * | 2011-03-03 | 2012-09-05 | 成都宇泽生物基因化妆品有限公司 | Moisturizing cream containing rose essence |
| CN102670459A (en) * | 2012-06-06 | 2012-09-19 | 桑达化工（南通）有限公司 | Anti-winkle lotion |
| CN104546603A (en) * | 2014-12-24 | 2015-04-29 | 陕西艾尔肤组织工程有限公司 | Composition with calming and relieving functions and preparation method thereof |
| CN105616325A (en) * | 2016-01-30 | 2016-06-01 | 海南京润珍珠生物技术股份有限公司 | Nacre-based tightening and moisturizing facial mask and manufacturing method thereof |
| CN106176452A (en) * | 2016-08-27 | 2016-12-07 | 朱耀灯 | A kind of deep water supplement moisturizing facial milk cleanser |
| CN106619274A (en) * | 2016-11-08 | 2017-05-10 | 宁夏艾伊生物工程研发有限公司 | Moisturizer and preparation method thereof |
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Application publication date: 20171010 |