It is a kind of to help to treat chewable tablets of bleeding gums and preparation method thereof
Technical field
The present invention relates to health product technology field, more particularly to a kind of chewable tablets and its system for helping to treat bleeding gums
Preparation Method.
Background technology
Bleeding gums are one of department of stomatology common symptons, refer to gum it is spontaneous or due to a small amount of caused by minimal irritation
Bleed.The trace of blood is carried in saliva when the lighter shows as only sucking, brushes teeth, chews harder food, severe one is in gum by slight
It is that bleeding is more or even hematostaxis during stimulation.In general, the chronic inflammation of gum is the common cause of bleeding gums, therefore
Bleeding gums are more common in periodontitis and gingivitis patients;But can also be the oral appearance of some systemic diseases sometimes, at this moment
It should give enough attention.
Issued by Asia dental aesthetics association《2014 oral health white paper and dental health guide handbook》It has been shown that, mistake
Sixty percent 6 ages virgin Primary Caries, teen-age caries prevalence rate is also close to three one-tenth within 12 years old.One of omen symptom as periodontitis, gum
The situation of bleeding is also very universal.Domestic oral health epidemiological survey data shows, 12 years old teenager's bleeding gums recall rate
It is 77.3% for the recall rate of 57.7%, 35-44 Sui a middle-aged person's bleeding gums, dental calculus recall rate is 97.3%, there is the tooth of dental calculus per capita
Number is 21.87;The periodontal health rate of 65-74 Sui the elderly is 14.1%, and the recall rate of bleeding gums is 68.0%.
Teenager carries out long-term treatment, traditional western medicine therapy due to learning tasks weight without time system to hospital
Easily recurrence, and Chinese medicine is bitter, therefore be necessary to study a kind of suitable teenager's long-term taking contribute to treatment bleeding gums
Chewable tablets.
The content of the invention
In order to solve the above problems, it is an object of the invention to provide it is a kind of contribute to treat bleeding gums chewable tablets and its
Preparation method.
Technical scheme is as follows:
A kind of chewable tablets for helping to treat bleeding gums, including following component:Traditional Chinese medicine ingredients, magnesium stearate, sucrose, starch and
Calcium carbonate.
It is preferred that, described contributes to the chewable tablets for the treatment of bleeding gums, includes the composition of following percentage by weight:Chinese medicine
Composition 2-8%, magnesium stearate 1-2.5%, sucrose 35-50%, starch 12-20% and calcium carbonate surplus.
It is preferred that, described traditional Chinese medicine ingredients, including following component:Chrysanthemum, honeysuckle, Lombardy poplar, Lindley Butterflybush Herb and radix glycyrrhizae.
It is preferred that, described traditional Chinese medicine ingredients include the composition of following percentage by weight:Chrysanthemum 65-75%, honeysuckle 8-
15%th, Lombardy poplar 2-5%, Lindley Butterflybush Herb 1-3% and radix glycyrrhizae surplus.
Lindley Butterflybush Herb dispelling wind and eliminating dampness, it is relieving cough and reducing sputum, dissipate the stasis of blood, desinsection.Bronchitis, cough, asthma, rheumatic arthritis is fallen
Play damage;Traumatic bleeding, burn and scald are controlled in external application, and are used as to kill maggot and are gone out wriggler.The difference of Lindley Butterflybush Herb and other Chinese medicines is nothing
It need to take orally, it is evident in efficacy after brushing teeth, after addition Lindley Butterflybush Herb is ground together with silica to tooth in the present invention, there is certain
The effect of dispelling wind and eliminating dampness, contributes to hemostasis.
Lombardy poplar cures mainly rheumatalgia pain, and tinea pedis swells:Bark is steep in wine clothes.With removing pattogenic heat from the blood and toxic material from the body;Effect of dispelling wind and eliminating dampness, equally
It is evident in efficacy after brushing teeth without for oral administration.
A kind of preparation method for helping to treat the chewable tablets of bleeding gums, comprises the following steps:
A, chrysanthemum, honeysuckle, Lombardy poplar, Lindley Butterflybush Herb and radix glycyrrhizae weighed in proportion;
B, the method that chrysanthemum, honeysuckle and radix glycyrrhizae are respectively adopted into supercritical fluid extraction are extracted, and using spray drying
Mode obtain extract;
C, Lombardy poplar and Lindley Butterflybush Herb crushed, and ground repeatedly after it is mixed with calcium carbonate, crossed 200 mesh sieves, obtain under sieve
Thing;
D, the screenings in the extract in step B, step C and remaining raw material are mixed after tabletting, you can.
The present invention is advantageous in that:The present invention's contributes to the chewable tablets for the treatment of bleeding gums, with clearing heat and detoxicating
Chrysanthemum and honeysuckle are primary raw material, then are aided with the good radix glycyrrhizae of antibacterial, antiviral effect, and with the liquor-saturated of dispelling wind and eliminating dampness effect
Water shield and Lombardy poplar, can just be eased in the short time to the symptom of bleeding gums;And the main component of the chewable tablets is
Chrysanthemum and honeysuckle, the effect with fresh breath;Adding calcium carbonate not only has grinding tooth surface, strengthens the effect of drug effect, and
And have calcium supplementing effect concurrently, it is particularly suitable for minor and takes.
Embodiment
The application principle of the present invention is explained in detail with specific embodiment below.
Embodiment 1
A kind of chewable tablets for helping to treat bleeding gums, includes the composition of following percentage by weight:Traditional Chinese medicine ingredients 5%, tristearin
Sour magnesium 2.2%, sucrose 45%, starch 18% and calcium carbonate surplus.
Described traditional Chinese medicine ingredients, include the composition of following percentage by weight:Chrysanthemum 72%, honeysuckle 10%, Lombardy poplar
4%th, Lindley Butterflybush Herb 2% and radix glycyrrhizae surplus.
Embodiment 2
A kind of chewable tablets for helping to treat bleeding gums, includes the composition of following percentage by weight:Traditional Chinese medicine ingredients 2%, tristearin
Sour magnesium 2.5%, sucrose 35%, starch 20% and calcium carbonate surplus.
Described traditional Chinese medicine ingredients, include the composition of following percentage by weight:Chrysanthemum 65%, honeysuckle 15%, Lombardy poplar
2%th, Lindley Butterflybush Herb 3% and radix glycyrrhizae surplus.
Embodiment 3
A kind of chewable tablets for helping to treat bleeding gums, includes the composition of following percentage by weight:Traditional Chinese medicine ingredients 8%, tristearin
Sour magnesium 1%, sucrose 50%, starch 12% and calcium carbonate surplus.
Described traditional Chinese medicine ingredients, include the composition of following percentage by weight:Chrysanthemum 75%, honeysuckle 8%, Lombardy poplar 5%,
Lindley Butterflybush Herb 1% and radix glycyrrhizae surplus.
Contribute to the preparation method of the chewable tablets for the treatment of bleeding gums above, comprise the following steps:
A, chrysanthemum, honeysuckle, Lombardy poplar, Lindley Butterflybush Herb and radix glycyrrhizae weighed in proportion;
B, the method that chrysanthemum, honeysuckle and radix glycyrrhizae are respectively adopted into supercritical fluid extraction are extracted, and using spray drying
Mode obtain extract;
C, Lombardy poplar and Lindley Butterflybush Herb crushed, and ground repeatedly after it is mixed with calcium carbonate, crossed 200 mesh sieves, obtain under sieve
Thing;
D, the screenings in the extract in step B, step C and remaining raw material are mixed after tabletting, you can.
The using effect to chewable tablets carries out clinical trial below, obtains following test result.
Subject Population:There is bleeding gums, the patient 200 of halitosis symptom, the age is 12-18 Sui, is divided into 1 group of embodiment
With two groups of control group;Wherein every group male 50, women 50.
3 for each person every day, the usage amount of each chewable tablets is 3g;Control group:Spiramvcin is treated.
Treatment and detection time:Continuously using after 15 days, detect for the first time;It is continuous to use 1 month, disable, second of inspection
Survey.
Efficacy evaluation:
It is invalid:Symptom is without alleviation or DeGrain.
Effectively:Symptom is significantly alleviated, and effect is obvious.
Cure:Symptom disappears, recovery from illness.
Recurrence:During second of detection, detect that the patient effectively or cured repeats bleeding gums symptom for the first time.
Table 1:The therapeutic effect of embodiment 1
By above clinical detection result it is recognised that chewable tablets not only instant effect, the good effect, and when taking one section of the present invention
Between after, recurrence can be prevented, and traditional antibiotic therapy method is very easy to recurrence.
Comparative example 1
Lombardy poplar in embodiment 1 and Lindley Butterflybush Herb are removed.
Comparative example 2
Lombardy poplar in embodiment 1 is removed.
Comparative example 3
Lindley Butterflybush Herb in embodiment 1 is removed.
Clinical trial is carried out to embodiment 1 and comparative example 1-3 sample by the above process, test crowd total number of persons is 200
Example, the age is 12-18 Sui, is divided into 4 groups.
Table 2:The contrast therapeutic effect of embodiment 1 and comparative example 1-3
By above test data it is recognised that the therapeutic effect of Lombardy poplar and Lindley Butterflybush Herb to chewable tablets in the traditional Chinese medicine ingredients of the present invention
Influence is notable, and recurrence rate is also had a certain impact, and Lombardy poplar and Lindley Butterflybush Herb have cooperative effect.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its
Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.