CN107212852B - Correction method and device for realizing scanning positions of various scanning imaging devices - Google Patents

Correction method and device for realizing scanning positions of various scanning imaging devices Download PDF

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CN107212852B
CN107212852B CN201710401767.9A CN201710401767A CN107212852B CN 107212852 B CN107212852 B CN 107212852B CN 201710401767 A CN201710401767 A CN 201710401767A CN 107212852 B CN107212852 B CN 107212852B
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scanning
image
angle
module
correction
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CN107212852A (en
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胡献恩
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Zd Mecical Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/12Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0016Operational features thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/102Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14Arrangements specially adapted for eye photography
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00Image enhancement or restoration
    • G06T5/80Geometric correction
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10101Optical tomography; Optical coherence tomography [OCT]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30041Eye; Retina; Ophthalmic

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Abstract

The invention discloses a correction method and a device for realizing scanning positions of various scanning imaging devices, wherein the method comprises the following steps: acquiring an eye image, and calculating the position offset of a second image by an image matching algorithm according to the first image as a reference; and performing scanning angle adjustment on the OCT equipment according to the mapping relation between the position offset and the pre-stored scanning angle and scanning range of the OCT equipment. The scanning image equipment and the OCT equipment are controlled to acquire the same eye to obtain a first image and a second image, the relative position offset of the second image relative to the first image is calculated by taking the first image as a reference, the correction angle is obtained according to the mapping relation between the pre-stored scanning angle and the scanning range, the scanning position of the OCT equipment is adjusted according to the correction angle, the correction result is more accurate, the correction result in the correction process is more accurate, and the whole correction process is repeatable.

Description

Correction method and device for realizing scanning positions of various scanning imaging devices
Technical Field
The present invention relates to the field of image processing technologies, and in particular, to a method and apparatus for correcting a scanning position of a plurality of scanning imaging devices.
Background
Currently, many optical coherence tomography scanners do not have linear scanning fundus imaging, and manual correction is used for scanning position correction of the scanner, and requires specialized personnel to operate.
However, the conventional technical solutions have the following drawbacks:
because the correction is performed manually, the correction result may be inaccurate, and because the professional performs position correction, the professional only judges whether the position correction is in place according to subjective judgment, and the correction result is inaccurate and poor in repeatability due to the fact that the correction is performed manually and the quantized data is not available.
Disclosure of Invention
In order to overcome the defects of the prior art, one of the purposes of the invention is to provide a correction method for realizing the scanning positions of various scanning imaging devices, which can solve the problems of inaccurate correction results and poor repeatability in the scanning position correction process of an optical coherence tomography scanner.
The second object of the present invention is to provide a correction device for realizing scanning positions of various scanning imaging apparatuses, which can solve the problems of insufficient accuracy and poor repeatability of correction results in the process of correcting scanning positions of an optical coherence tomography scanner.
One of the purposes of the invention is realized by adopting the following technical scheme:
a correction method for realizing scanning positions of a plurality of scanning imaging apparatuses, the method comprising:
acquiring an image of an eye, acquiring the eye by using a scanning imaging device to obtain a first image, and acquiring the eye by using an OCT device to obtain a second image;
obtaining the position offset of the second image relative to the first image by an image matching algorithm according to the first image as a reference;
obtaining a correction angle according to the mapping relation between the position offset and a pre-stored scanning angle and scanning range of the OCT equipment, sending an angle compensation instruction to the OCT equipment according to the correction angle, and performing angle compensation by the OCT equipment according to the angle compensation instruction.
Further, the method further comprises the steps of: establishing a mapping relation between the scanning angle and the scanning range, adjusting the scanning angle of the OCT equipment to obtain an image of a corresponding position, determining the scanning range according to the image of the corresponding position, obtaining a mapping relation between the scanning angle of the OCT equipment and the scanning range according to the scanning angle and the scanning range, and storing the mapping relation to obtain a pre-stored mapping relation between the scanning angle of the OCT equipment and the scanning range.
Further, the OCT apparatus performs angle compensation according to the angle compensation instruction, specifically, a moving component of the OCT apparatus receives the angle compensation instruction and converts the angle compensation instruction into a position movement amount according to which the moving component performs position movement.
The second purpose of the invention is realized by adopting the following technical scheme:
a correction apparatus for realizing a plurality of scanning positions of a scanning image forming apparatus, the apparatus comprising: the OCT device comprises a scanning imaging module, an OCT module, a compensation correction module, a storage module and a control module, wherein the storage module is connected with the scanning imaging module, the storage module is connected with the OCT module, the scanning imaging module is connected with the compensation correction module, the compensation correction module is connected with the storage module, the control module is connected with the storage module, and the control module is connected with the OCT module;
the storage module stores the mapping relation between the scanning angle and the scanning range of the OCT module, the scanning imaging module collects the eyes to obtain a first image, and the OCT module collects the eyes to obtain a second image;
the scanning imaging module sends a first image to the compensation correction module, and the OCT module sends the second image to the compensation correction module;
the compensation correction module receives the first image and the second image, obtains the position offset of the second image relative to the first image through an image matching algorithm according to the first image, reads the mapping relation between the pre-stored scanning angle and the scanning range of the OCT module in the storage module, calculates according to the position offset and the pre-stored mapping relation between the scanning angle and the scanning range of the OCT module, and obtains a correction angle, and sends the correction angle to the storage module;
the storage module receives the correction angle and stores the correction angle, the control module reads the correction angle through the storage module and sends an angle compensation instruction to the OCT module according to the correction angle, the OCT module receives the angle compensation instruction, and the OCT module performs angle compensation according to the angle compensation instruction.
Further, the control module comprises a reading unit and an executing unit, the reading unit is connected with the executing unit, the executing unit is connected with the OCT module, the reading unit is used for reading the correction angle, and the executing unit is used for sending an angle compensation instruction to the OCT module according to the correction angle.
Further, the OCT module includes a moving component that adjusts a scan angle of the OCT module according to the angle compensation instruction, the moving component being a motor or MEMS.
Further, the compensation and correction module comprises an offset calculation unit and a correction angle calculation unit, wherein the offset calculation unit is connected with the correction angle calculation unit and is used for obtaining the position offset of the second image relative to the first image through an image matching algorithm according to the first image as a reference; the correction angle calculation unit is used for calculating according to the position offset and a pre-stored mapping relation between the scanning angle and the scanning range of the OCT module to obtain a correction angle.
Further, the scanning imaging module includes a fundus camera.
Compared with the prior art, the invention has the beneficial effects that: the scanning imaging device and the OCT device are controlled to acquire a first image and a second image of the same eye, the computing device is used for taking the first image as a reference, the relative position offset of the second image relative to the first image is calculated, the correction angle is obtained according to the mapping relation between the pre-stored scanning angle and the scanning range, the scanning position of the OCT device is adjusted according to the correction angle, the correction result in the correction process is more accurate, and the whole correction process is repeatable.
Drawings
FIG. 1 is a flow chart of a correction method for implementing scanning positions of a plurality of scanning imaging devices according to the present invention;
FIG. 2 is a system block diagram of a correction device for implementing a plurality of scanning positions of a scanning imaging apparatus according to the present invention;
FIG. 3 is a block diagram of a compensation correction module for implementing a correction device for scanning positions of a plurality of scanning imaging devices according to the present invention;
fig. 4 is a block diagram showing the configuration of a control module of a correction device for realizing a plurality of scanning positions of a scanning image forming apparatus according to the present invention.
Fig. 5 is an imaging optical path diagram of the fundus camera and OCT apparatus of the present invention;
FIG. 6 is an imaging optical path diagram of the OCT device of the present invention;
fig. 7 is an imaging optical path diagram of a fundus camera in the present invention;
FIG. 8 is a comparison of the positional shift of the first image and the second image according to the present invention;
fig. 9 is a position contrast diagram of the first image and the second image after the OCT apparatus of the present invention performs angle compensation.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and detailed description, wherein, on the premise of no conflict, the following embodiments or technical features can be arbitrarily combined to form new embodiments:
fig. 1 is a flowchart of a correction method for realizing scanning positions of a plurality of scanning image forming apparatuses according to the present invention, as shown in fig. 1, the method comprising the steps of:
step S10: the method comprises the steps of obtaining corresponding images when scanning angles of different OCT equipment are obtained, adjusting the scanning angles of the OCT equipment to obtain images of corresponding positions, wherein the OCT equipment is a coherent and surface imaging equipment, the specific OCT equipment imaging optical path process is shown in fig. 6, the OCT equipment comprises a broadband light source SLD, the OCT equipment comprises a moving part, the moving part comprises a scanning part 1, a scanning part 2 and a scanning part 3, the light source is divided into a reference optical path and an optical path entering human eyes through an optical fiber coupler, the light source is reflected after entering the human eyes, reflected light passes through the eyepiece and the scanning part 3, the scanning part 1 and the scanning part 2 of the OCT, a detector receives the reflected light, the reflected light is subjected to signal processing to obtain images, the images are sent to a computer, and the scanning angles of the OCT are changed by adjusting the positions of the scanning parts in fig. 6, so that the corresponding images are obtained.
Step S20: the scanning range corresponding to the corresponding scanning angle of the OCT device is determined according to the image of the corresponding position, and the image obtained by the OCT device corresponding to the scanning angle is different, so that the scanning range corresponding to the scanning angle of the OCT device is obtained according to the image of the corresponding scanning position.
Step S30: obtaining a pre-stored mapping relation between the scanning angle and the scanning range of the OCT equipment according to the scanning angle and the scanning range, calculating the mapping relation between the scanning angle and the scanning range of the OCT equipment according to the scanning angle and the scanning range corresponding to the scanning angle of the OCT equipment, and storing the mapping relation between the scanning angle and the scanning range of the OCT equipment to obtain the pre-stored mapping relation between the scanning angle and the scanning range of the OCT equipment.
Step S40: acquiring an image of an eye to obtain a first image and a second image, controlling a scanning imaging device to acquire the eye to obtain the first image, wherein the scanning imaging device comprises a fundus camera, and reflected light emitted by the eye enters the fundus camera through an eyepiece and a scanning component 3 to obtain the first image as shown in fig. 5 and 7; as shown in fig. 5-6, the OCT apparatus is controlled to acquire the same eye to obtain a second image, and reflected light emitted by the human eye is received by the detector again through the eyepiece and the scanning component 1, the scanning component 2 and the scanning component 3, and then is input into the computer to obtain the second image after signal processing; the obtained comparison graph of the position offset of the first image and the second image is shown in fig. 8, wherein the quadrangular image at the central position in fig. 8 is the first image, the image at the periphery of the quadrangular image is the second image, and the second image has the position offset compared with the first image.
Step S50: according to the first image as a reference, the position offset of the second image is calculated through an image matching algorithm, the first image and the second image are images obtained by scanning the same eye part through two different devices, and the resolution and the accuracy of an imaging picture of the scanning imaging device are higher.
Step S60: the correction angle is obtained according to the mapping relation between the position offset and the scanning angle and scanning range of the OCT device, and the correction angle is obtained according to the mapping relation between the position offset and the pre-stored scanning angle and scanning range of the OCT device.
Step S70: correcting the scanning angle of the OCT apparatus according to the correction angle, transmitting an angle compensation instruction to the OCT apparatus according to the correction angle in step S70, the OCT apparatus performing angle compensation according to the angle compensation instruction specifically being: the moving part of the OCT apparatus receives the angle compensation instruction and converts the angle compensation instruction into a position movement amount, the moving part performs a position movement according to the position movement amount, the moving part of the OCT apparatus performs angle compensation on a scanning angle of the OCT apparatus by adjusting a direction and a position of a scanning part in the moving part according to the position movement amount, and after performing angle compensation on the scanning angle, a comparison diagram of a first image and a second image is shown in fig. 9, and a position offset of the first image and the second image is corrected without an offset phenomenon.
As shown in fig. 2-4, the apparatus includes: the OCT imaging device comprises a scanning imaging module, an OCT module, a compensation correction module, a storage module and a control module, wherein the scanning imaging module comprises a fundus camera, the OCT module comprises OCT imaging equipment, the compensation correction module comprises an offset calculation unit and a correction angle calculation unit, the control module comprises a reading unit and an execution unit, the storage module is connected with the scanning imaging module, the storage module is connected with the OCT module, the scanning imaging module is connected with the compensation correction module, the compensation correction module is connected with the storage module, the control module is connected with the OCT module, the reading unit is connected with the execution unit, the execution unit is connected with the OCT module, and the offset calculation unit is connected with the correction angle calculation unit.
The scanning imaging module collects the eyes to obtain a first image, the scanning imaging module comprises scanning imaging equipment, the scanning imaging equipment is a fundus camera, the scanning imaging module collects the eyes to obtain a fundus camera, an imaging light path diagram of the fundus camera for collecting the eyes is shown in fig. 5 and 7, and reflected light emitted by the eyes enters the fundus camera through an eyepiece and a scanning component 3 to obtain the first image; the OCT module collects the eyes, namely the OCT equipment collects the same eyes to obtain a second image, the specific OCT equipment imaging light path process is shown in fig. 6, the OCT equipment comprises a broadband light source SLD, the OCT equipment comprises a moving part, the moving part comprises a scanning part 1, a scanning part 2 and a scanning part 3, the scanning part is a motor or MEMS, and the MEMS is a micro system comprising a micro sensor, a micro actuator, a micro electronic signal processing and controlling circuit and other parts; dividing a light source into a reference light path and a light path entering human eyes through an optical fiber coupler, reflecting the light source after entering the human eyes, receiving the reflected light by a detector through a scanning component 3, a scanning component 1 and a scanning component 2 of an ocular lens and OCT, performing signal processing on the reflected light to obtain an image, and sending the image to a computer to obtain a second image; the obtained comparison graph of the position offset of the first image and the second image is shown in fig. 8, wherein the quadrangular image at the central position in fig. 8 is the first image, the image at the periphery of the quadrangular image is the second image, and the second image has the position offset compared with the first image.
The scanning imaging module sends a first image to the compensation correction module, and the OCT module sends a second image to the compensation correction module; the compensation correction module receives the first image and the second image, and obtains the position offset of the second image relative to the first image through an image matching algorithm according to the first image as a reference; the compensation correction module reads a pre-stored mapping relation between the scanning angle and the scanning range of the OCT module in the storage module, calculates according to the position offset and the pre-stored mapping relation between the scanning angle and the scanning range of the OCT module to obtain a correction angle, and comprises an offset calculation unit and a correction angle calculation unit, wherein the offset calculation unit is used for calculating the position offset of the second image by an image matching algorithm according to the first image as a reference; the correction angle calculation unit is used for calculating according to the position offset and the mapping relation between the scanning angle and the scanning range of the pre-stored OCT module to obtain a correction angle;
the compensation correction module sends the correction angle to the storage module, and the storage module receives the correction angle and stores the correction angle; the control module reads the correction angle through the storage module and sends an angle compensation instruction to the OCT module according to the correction angle, the OCT module performs angle compensation according to the angle compensation instruction, the control module comprises a reading unit and an execution unit, the reading unit is used for reading the correction angle, the execution unit is used for sending the angle compensation instruction to the OCT module according to the correction angle, the OCT module performs angle compensation according to the angle compensation instruction, after performing angle compensation on the scanning angle, a comparison diagram of a first image and a second image is shown in fig. 9, the position offset of the first image and the second image is corrected, and no offset phenomenon exists.
The invention discloses a correction method and a correction device for realizing the scanning positions of various scanning imaging equipment, which are characterized in that the scanning imaging equipment and OCT equipment are controlled to acquire a first image and a second image of the same eye, the calculation equipment is used for calculating the relative position offset of the second image relative to the first image by taking the first image as a reference, the correction angle is obtained according to the mapping relation between the pre-stored scanning angle and the scanning range, the scanning position of the OCT equipment is adjusted according to the correction angle, the correction result in the correction process is more accurate, and the whole correction process is repeatable.
It will be apparent to those skilled in the art from this disclosure that various other changes and modifications can be made which are within the scope of the invention as defined in the appended claims.

Claims (7)

1. A correction method for realizing scanning positions of a plurality of scanning image forming apparatuses, comprising:
acquiring an image of an eye, acquiring the eye by using a scanning imaging device to obtain a first image, and acquiring the eye by using an OCT device to obtain a second image;
obtaining the position offset of the second image relative to the first image by an image matching algorithm according to the first image as a reference;
obtaining a correction angle according to the mapping relation between the position offset and a pre-stored scanning angle and scanning range of the OCT equipment, sending an angle compensation instruction to the OCT equipment according to the correction angle, and performing angle compensation by the OCT equipment according to the angle compensation instruction.
2. A correction method for realizing scanning positions of a plurality of scanning image forming apparatuses as claimed in claim 1, wherein: the method also comprises the steps of: establishing a mapping relation between the scanning angle and the scanning range, adjusting the scanning angle of the OCT equipment to obtain an image of a corresponding position, determining the scanning range according to the image of the corresponding position, obtaining a mapping relation between the scanning angle of the OCT equipment and the scanning range according to the scanning angle and the scanning range, and storing the mapping relation to obtain a pre-stored mapping relation between the scanning angle of the OCT equipment and the scanning range.
3. A correction method for realizing scanning positions of a plurality of scanning image forming apparatuses as claimed in claim 1, wherein: the OCT apparatus performs angle compensation according to the angle compensation instruction, specifically, a moving component of the OCT apparatus receives the angle compensation instruction and converts the angle compensation instruction into a position movement amount according to which the moving component performs position movement.
4. A correction device for realizing scanning positions of a plurality of scanning image forming apparatuses, comprising: the OCT device comprises a scanning imaging module, an OCT module, a compensation correction module, a storage module and a control module, wherein the storage module is connected with the scanning imaging module, the storage module is connected with the OCT module, the scanning imaging module is connected with the compensation correction module, the compensation correction module is connected with the storage module, the control module is connected with the storage module, and the control module is connected with the OCT module;
the storage module stores the mapping relation between the scanning angle and the scanning range of the OCT module, the scanning imaging module collects the eyes to obtain a first image, and the OCT module collects the eyes to obtain a second image;
the scanning imaging module sends a first image to the compensation correction module, and the OCT module sends the second image to the compensation correction module;
the compensation correction module receives the first image and the second image, obtains the position offset of the second image relative to the first image through an image matching algorithm according to the first image, reads the mapping relation between the pre-stored scanning angle and the scanning range of the OCT module in the storage module, calculates according to the position offset and the pre-stored mapping relation between the scanning angle and the scanning range of the OCT module, and obtains a correction angle, and sends the correction angle to the storage module;
the storage module receives the correction angle and stores the correction angle, the control module reads the correction angle through the storage module and sends an angle compensation instruction to the OCT module according to the correction angle, the OCT module receives the angle compensation instruction, and the OCT module performs angle compensation according to the angle compensation instruction;
the OCT module comprises a moving component which adjusts the scanning angle of the OCT module according to the angle compensation instruction.
5. A correction device for realizing a plurality of scanning positions of a scanning image forming apparatus as claimed in claim 4, wherein: the control module comprises a reading unit and an executing unit, wherein the reading unit is connected with the executing unit, the executing unit is connected with the OCT module, the reading unit is used for reading the correction angle, and the executing unit is used for sending an angle compensation instruction to the OCT module according to the correction angle.
6. A correction device for realizing a plurality of scanning positions of a scanning image forming apparatus as claimed in claim 4, wherein: the compensation and correction module comprises an offset calculation unit and a correction angle calculation unit, wherein the offset calculation unit is connected with the correction angle calculation unit and is used for obtaining the position offset of a second image relative to a first image through an image matching algorithm according to the first image as a reference; the correction angle calculation unit is used for calculating according to the position offset and a pre-stored mapping relation between the scanning angle and the scanning range of the OCT module to obtain a correction angle.
7. A correction device for realizing a plurality of scanning positions of a scanning image forming apparatus as claimed in claim 4, wherein: the scanning imaging module includes a fundus camera.
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