CN107184871A - Gouty nephropathy Chinese medicine composition and preparation method - Google Patents
Gouty nephropathy Chinese medicine composition and preparation method Download PDFInfo
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Abstract
Gouty nephropathy Chinese medicine composition and preparation method.A kind of gouty nephropathy Chinese medicine composition, its composition includes:Salt processs plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae, it is characterized in that:The parts by weight that described salt processs plantain seed are 15 20, the parts by weight of the described root bark of shaggy-fruited dittany are 10 15, the parts by weight of described coix seed are 25 30, the parts by weight of described propolis are 0.3 0.5, the parts by weight of described desmodium are 35 40, a kind of preparation method of gouty nephropathy Chinese medicine composition, weigh above-mentioned salt and process plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae and crush respectively, then cross 40 70 mesh sieve.The present invention is used for gouty nephropathy.
Description
Technical field：
The present invention relates to a kind of gouty nephropathy Chinese medicine composition and preparation method.
Background technology：
The people for being now arranged in inferior health is a lot, and the people in gouty nephropathy is also a lot, due to gouty nephropathy, and the body of these people is good for
All there is hidden danger in health, the effect of existing gouty nephropathy western medicine is all bad.
The content of the invention：
Being capable of gouty nephropathy Chinese medicine composition and preparation method it is an object of the invention to provide one kind.
Above-mentioned purpose is realized by following technical scheme：
1. a kind of gouty nephropathy Chinese medicine composition, its composition includes:Salt process plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium,
Carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae, it is characterized in that:The parts by weight that described salt processs plantain seed are 15-20, described
The parts by weight of the root bark of shaggy-fruited dittany are 10-15, and the parts by weight of described coix seed are 25-30, and the parts by weight of described propolis are
0.3-0.5, the parts by weight of described desmodium are 35-40, and the parts by weight of described carrot skin are 70-90, described
The parts by weight of giant knotweed are 10-12, and the parts by weight of the described life Radix Astragali are 10-15, and the parts by weight of described radix cyathulae are
6-7。
The parts by weight that described salt processs plantain seed are 15, and the parts by weight of the described root bark of shaggy-fruited dittany are 10, described Job's tears
The parts by weight of benevolence are 25, and the parts by weight of described propolis are 0.3, and the parts by weight of described desmodium are 35, described
The parts by weight of carrot skin are 70, and the parts by weight of described giant knotweed are 10, and the parts by weight of the described life Radix Astragali are 10, institute
The parts by weight for the radix cyathulae stated are 6.
The parts by weight that described salt processs plantain seed are 20, and the parts by weight of the described root bark of shaggy-fruited dittany are 15, described Job's tears
The parts by weight of benevolence are 30, and the parts by weight of described propolis are 0.5, and the parts by weight of described desmodium are 40, described
The parts by weight of carrot skin are 90, and the parts by weight of described giant knotweed are 12, and the parts by weight of the described life Radix Astragali are 15, institute
The parts by weight for the radix cyathulae stated are 7.
The parts by weight that described salt processs plantain seed are 18, and the parts by weight of the described root bark of shaggy-fruited dittany are 12, described Job's tears
The parts by weight of benevolence are 28, and the parts by weight of described propolis are 0.4, and the parts by weight of described desmodium are 38, described
The parts by weight of carrot skin are 75, and the parts by weight of described giant knotweed are 11, and the parts by weight of the described life Radix Astragali are 11, institute
The parts by weight for the radix cyathulae stated are 7.
A kind of preparation method of gouty nephropathy Chinese medicine composition, it is characterized in that:Weigh above-mentioned salt process plantain seed, the root bark of shaggy-fruited dittany,
Coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, then cross 40-70 mesh
Sieve, plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, river ox are processed by the salt after crushing
Knee, which is sufficiently mixed, is made mixed powder, is soaked in mixed powder after 2-3h, and water needs foam mixed powder, decocts 2-4 times,
Each 1-2h, pours out filtering, is sufficiently mixed, merging filtrate, is concentrated into 100ml, standby.
Weigh salt and process plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae
Parts by weight are crushed respectively, then cross 70 mesh sieve, the salt after crushing is processed into plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, money
Grass, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae are sufficiently mixed and mixed powder are made, and are soaked in mixed powder after 3h, water
Need foam mixed powder, decoct 4 times, each 2h pours out filtering, be sufficiently mixed, merging filtrate, be concentrated into 100ml, it is standby.
Weigh salt and process plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae
Parts by weight are crushed respectively, then cross 40 mesh sieve, the salt after crushing is processed into plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, money
Grass, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae are sufficiently mixed and mixed powder are made, and are soaked in mixed powder after 2h, water
Need foam mixed powder, decoct 2 times, each 1h pours out filtering, be sufficiently mixed, merging filtrate, be concentrated into 100ml, it is standby.
Weigh salt and process plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae
Parts by weight are crushed respectively, then cross 60 mesh sieve, the salt after crushing is processed into plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, money
Grass, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae are sufficiently mixed and mixed powder are made, and are soaked in mixed powder after 4h, water
Need foam mixed powder, decoct 3 times, each 2h pours out filtering, be sufficiently mixed, merging filtrate, be concentrated into 100ml, it is standby.
Beneficial effect：
First, result of the present invention shows Chinese medicine composition PTCA or and STENTS, and glomerular capillary is opened and significantly reduced, and crystallization is obvious
Reduce, dyeing weakens（Acidophilia weakens）, renal lesions is improved significantly, and there is no any side effect.
2nd, Chinese medicine composition of the present invention is playing the effect of antigout nephrosis simultaneously, can reduce gouty nephropathy etc. and cause pain
The writhing number of times of pain and reaction, with preferable analgesic activity.
3rd, Chinese medicine composition PTCA or and STENTS of the present invention, is playing obvious antigout nephrosis effect said composition energy simultaneously
Enough adequately protect cerebral apoplexy nerve, has therapeutic effect to cerebral arterial thrombosis.
4th, present invention selection salt processs plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, raw Huang
The Chinese medicines such as stilbene, radix cyathulae are the summaries of many years of experience, and Chinese medicinal formulae uses natural Chinese medicinal herb, had no side effect safely, Chinese medicinal formulae
Not only drug effect enhancing treatment gouty nephropathy effect is good but also without any side effect for compatibility synergy between middle multicomponent.
Brief description of the drawings：
Accompanying drawing 1 is this product HE dyeing pathology figures.
Embodiment：
Below in conjunction with the accompanying drawing of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described.
Embodiment 1：
1. a kind of gouty nephropathy Chinese medicine composition, its composition includes:Salt process plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium,
Carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae, the parts by weight that described salt processs plantain seed are 15-20, the weight of the described root bark of shaggy-fruited dittany
Amount number is 10-15, and the parts by weight of described coix seed are 25-30, and the parts by weight of described propolis are 0.3-0.5, institute
The parts by weight for the desmodium stated are 35-40, and the parts by weight of described carrot skin are 70-90, the weight of described giant knotweed
Number is 10-12, and the parts by weight of the described life Radix Astragali are 10-15, and the parts by weight of described radix cyathulae are 6-7.
Embodiment 2：
A kind of gouty nephropathy Chinese medicine composition, the parts by weight that described salt processs plantain seed are 15, the weight of the described root bark of shaggy-fruited dittany
Number is 10, and the parts by weight of described coix seed are 25, and the parts by weight of described propolis are 0.3, described desmodium
Parts by weight are 35, and the parts by weight of described carrot skin are 70, and the parts by weight of described giant knotweed are 10, described life
The parts by weight of the Radix Astragali are 10, and the parts by weight of described radix cyathulae are 6.
Embodiment 3：
A kind of gouty nephropathy Chinese medicine composition, the parts by weight that described salt processs plantain seed are 20, the weight of the described root bark of shaggy-fruited dittany
Number is 15, and the parts by weight of described coix seed are 30, and the parts by weight of described propolis are 0.5, described desmodium
Parts by weight are 40, and the parts by weight of described carrot skin are 90, and the parts by weight of described giant knotweed are 12, and described is raw yellow
The parts by weight of stilbene are 15, and the parts by weight of described radix cyathulae are 7.
Embodiment 4：
A kind of gouty nephropathy Chinese medicine composition, the parts by weight that described salt processs plantain seed are 18, the weight of the described root bark of shaggy-fruited dittany
Number is 12, and the parts by weight of described coix seed are 28, and the parts by weight of described propolis are 0.4, described desmodium
Parts by weight are 38, and the parts by weight of described carrot skin are 75, and the parts by weight of described giant knotweed are 11, described life
The parts by weight of the Radix Astragali are 11, and the parts by weight of described radix cyathulae are 7.
Embodiment 5：
A kind of preparation method of gouty nephropathy Chinese medicine composition, weighs above-mentioned salt and processs plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, gold
Money grass, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, 40-70 mesh sieve are then crossed, after crushing
Salt process plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae and be sufficiently mixed and be made
Mixed powder, is soaked after 2-3h in mixed powder, and water needs foam mixed powder, is decocted 2-4 times, each 1-2h is poured out
Filtering, is sufficiently mixed, merging filtrate, is concentrated into 100ml, standby.
Embodiment 6：
A kind of preparation method of gouty nephropathy Chinese medicine composition, weighs salt and processs plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, money
Grass, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, then cross 70 mesh sieve, the salt after crushing is processed
Plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae are sufficiently mixed and mixing medicine are made
Powder, is soaked after 3h in mixed powder, and water needs foam mixed powder, is decocted 4 times, each 2h pours out filtering, fully mixed
Conjunction, merging filtrate, are concentrated into 100ml, standby.
Embodiment 7：
A kind of preparation method of gouty nephropathy Chinese medicine composition, weighs salt and processs plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, money
Grass, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, then cross 40 mesh sieve, the salt after crushing is processed
Plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae are sufficiently mixed and mixing medicine are made
Powder, is soaked after 2h in mixed powder, and water needs foam mixed powder, is decocted 2 times, each 1h pours out filtering, fully mixed
Conjunction, merging filtrate, are concentrated into 100ml, standby.
Embodiment 8：
A kind of preparation method of gouty nephropathy Chinese medicine composition, weighs salt and processs plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, money
Grass, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, then cross 60 mesh sieve, the salt after crushing is processed
Plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae are sufficiently mixed and mixing medicine are made
Powder, is soaked after 4h in mixed powder, and water needs foam mixed powder, is decocted 3 times, each 2h pours out filtering, fully mixed
Conjunction, merging filtrate, are concentrated into 100ml, standby.
Gouty nephropathy modeling：
Take body weight (150 ~ 170) g male Wistar rat 60, test it is preposition in laboratory (26 DEG C of environment temperature, relatively
Humidity 60%) environment is adapted to, after one week, rat is randomly divided into 6 groups, respectively blank control group, model group, positive drug（Not
Purine）Group, prescription high dose group（9ml/kg）, prescription middle dose group（6ml/kg）, prescription low dose group（3ml/kg）, use
Picric acid dye marker, every group 10.
Modeling and medication
After adaptability is raised one week, Normal group limitation feeding, by every experimental mouse lOOg/kg/d feeding generic word material, together
Shi Jinhang physiological saline equivalent stimulability with irrigation 5 weeks.Weigh in weekly, observe physiological status, changes of weight, diet, drinking-water shape
Condition etc.；The high, medium and low dosage group limitation high yeast feed of feeding of model group, positive drug group prescription, feeding amount is every experimental mouse
LOOg/kg/d, while gavage gives adenine modeling, administration concentration is lOmg/ml, and dosage is 100 mg/kg, gavage 5
Week.Weigh in weekly, observe its physiological status, changes of weight, diet, drinking-water situation etc..The high, medium and low dosage group of prescription and
Other purine group starts to give above-mentioned medicine, fills administration 2 weeks when modeling proceeds to the 2nd week.Weigh in weekly, observe
Its physiological status, changes of weight, diet, drinking-water situation.
Index is selected and detection
2.1 twenty-four-hour urine protein quantifications
24h before rat is put to death respectively at the 2nd weekend, 3 weekends and 5 weeks before experiment, after formal modeling, and rat is put into metal metabolism
It is accurate to collect 24h urines in cage, survey 24h urine protein contents.The quantitative use quantity of proteinuria kit CBB methods of 24h Urine proteins
Determine.
Blood bio-chemistry checking
Each group rat is after formal modeling the 5th week with 20% urethane (1mL/ 100g) intraperitoneal injection of anesthesia.Arteria carotis takes blood, in
3000r/min, 10 min separation serum is centrifuged at 4 DEG C.Automatic clinical chemistry analyzer determines total serum protein (TP), serum uric acid
(UA), 5 biochemical indicators such as serum bladder chalone C (cystatin C), serum creatinine (Scr), serum urea nitrogen (BUN).
The measure of rat renal index
5th weekend record rat body weight (g), wins the renal index that bilateral renal is weighed and calculates each group rat, renal index=bilateral
Kidney weight/body weight × 100%.
The measure of Serum antioxidant indices
Arteria carotis takes blood at the end of experiment, separates in serum, detection serum the vigor of superoxide dismutase dark (SOD) and the third two
The content of aldehyde (MDA).
Effect to immune inflammation cell factor
Arteria carotis takes blood at the end of experiment, separates serum, and plantain seed chemical resolution component is observed to gout kidney using ELISA method
The expression of TNF-α, IL-1 β and TGF-β 1 in sick rat blood serum.
Renal pathology morphological observation
2.6.1 nephridial tissue is taken
After experiment terminates, light microscopic, Electronic Speculum and SABC inspection are made using internal perfusion materials.
Internal method for filling：With 20% urethane (1mL/100g) intraperitoneal injection of anesthesia, left ventricle inserting needle behind thoracic cavity is opened,
Right auricle of heart saline infusions are cut off, the blood of the circulatory system are gone out and untill the liquid of outflow does not have color, then use
4% paraformaldehyde phosphoric acid buffer perfusion, is filled into each internal organs and hardens, and taking-up kidney will lose after shape face is splitted and be fixed on 4% poly
In formaldehyde phosphate buffer, HE, PAS dyeing light microscopy checking and SABC inspection are given over to, the sample of transmission electron microscope is done, takes kidney skin
Matter is cut into 1mm3Fritter, be fixed in 2.5% glutaraldehyde.
Dyeing
FFPE, conventional section will cut into slices into dimethylbenzene, aquation, be contaminated with haematoxylin dye liquor, washing, eosin stain speed dye,
It will cut into slices again through gradient alcohol dehydration, dimethylbenzene is transparent, resin glue sealing, observes under an optical microscope.
As a result
The influence of 3.1 pairs of gouty nephropathy rat 24h Urine proteins
From table .1, the Urine proteins of each group are apparently higher than before modeling after modeling 2 weeks, and model group is compared with blank control group, tool
Have pole significant difference (P<0.01).Difference that each administration group is compared that there are no significant with model group (P>0.05)；Modeling 3 weeks, i.e.,
Be administered after 1 week, high dose group Urine proteins significantly lower than model group (P<0.05), other purine group and model group difference extremely significantly (P
<0.01)；Modeling terminates on the 5th week, i.e., drug treatment 3 weeks when, compared with model group, other purine group, high dose group, middle dose group
Salient pole significant difference (P<0.01), low dose group in significant difference (P<0.05), three groups of prescription described above can reduce pain
The content of wind nephrotic rats 24h albuminuria.As a result Tab2.1 and Fig2.1 are seen.
3.2 pairs of gouty nephropathy rat blood biochemicals
1. serum urea nitrogen (BUN), the change of serum creatinine (Scr) level
As shown in Table 2, model group serum BUN, Scr it is significantly raised compared with Normal group (P<0.01), other purine group, high dose and
Middle dose group serum BUN, Scr be substantially less than model group (P<0.01 or P<0.05)；Low dosage administration group is compared equal with model group
There was no significant difference (P>0.05)。
2. total serum protein (TP), serum uric acid (UA), the change of serum bladder chalone C (cystatin C) level in serum
As shown in Table 2, model group serum T P substantially reduced compared with Normal group (P<0.01), other purine group and high dose group serum
TP poles be significantly higher than model control group (P<0.01)；Difference that remaining 2 administration groups are compared that there are no significant with model control group (P>
0.05).Model group serum UA, cystatin C be significantly higher than Normal group (P<0.01), other purine group, high dose and middle dose
Amount group serum UA, cystatin C poles be substantially less than model group (P<0.01)；Low dosage administration group is compared with model group to be had significantly
Sex differernce (P<0.05)。
The influence of 3.3 pairs of gouty nephropathy rat renal indexs
As shown in Table 3, in addition to blank control group, each experimental group Rat renal is significantly increased again, model group, other purine group and blank pair
Compare according to group, salient pole significant difference (P<0.01).High dose group rat renal index is compared with model control group, has conspicuousness poor
Different (P<0.05)。
The influence of 3.4 pairs of gouty nephropathy rat blood serum Antioxidant Indexes
As shown in Table 4, model group rats serum activity of SOD and MDA contents substantially reduced compared with Normal group (P<0.01) it is, not fast
Purine group, high dose and middle dose group serum activity of SOD be significantly higher than model control group (P<0.05)；And MDA contents are substantially less than
Model group (P<0.05)；Difference that low dose group is compared that there are no significant with model control group (P>0.05)。
The effect of immunoinflammatory cytokine-expressing in 3.5 pairs of gouty nephropathy rat blood serums
1. to the influence of TNF-α content in serum
As shown in Table 5, in model group rats serum TNF-α height expression, compared with Normal group salient pole significant difference (P<
0.01)；The expression of TNF-α salient pole compared with model group is notable in other purine group, high dose and middle dose group rat blood serum
Sex differernce (P<0.01)；Difference that low dosage administration group is compared that there are no significant with model group (P>0.05), illustrate high dose with
Dosage group has the effect for suppressing that TNF-α is expressed in gouty nephropathy rat blood serum.
2. to the influence of IL-1 β contents in serum
As shown in Table 5, in model group rats serum IL-1 β expression apparently higher than Normal group (P<0.01)；Each administration group
After drug treatment, in other purine group, high dose and middle dose group rat blood serum IL-1 β expression substantially reduced compared with model group (P<
0.05), the low dose group difference that compares that there are no significant (P>0.05), illustrate that high dose and middle dose group have and suppress gouty nephropathy
The effect 1 that IL-1 β are expressed in rat blood serum.
3. to the influence of the content of TGF-β in serum 1
As shown in Table 5, in model group rats serum TGF-β 1 expression apparently higher than Normal group (P<0.01)；Each administration group
After drug treatment, in other purine group rat blood serum the expression of TGF-β 1 compared with model group salient pole significant difference (P<
0.01), high dose group compared with model group show significant difference (P<0.05), remaining administration group is compared equal nothing with model control group
Significant difference (P>0.05), illustrate that high dose group has the effect for suppressing that TGF-β 1 is expressed in gouty nephropathy rat blood serum.
The influence of 3.6 pairs of gouty nephropathy renal tissues of rats pathology
3.6.1 HE chromoscopy results
Each group rat kidney is observed after HE dyeing through fixation, conventional embedding, film-making, as a result shows blank control group glomerulus shape
State is normal, and model group glomerular volume increase, balloon interstices are broadening, and glomerular capillary is in open state, and tube wall substantially increases
Thickness, dyeing enhancing（Acidophilia strengthens）, capillary ball is in lobulated, it is seen that obvious crystalloid material；Compared with model group,
After other purine group, high dose group and middle dose group treatment, glomerular capillary is opened and significantly reduced, and crystallization is significantly reduced, dye
Color weakens（Acidophilia weakens）, renal lesions is improved significantly, Fig. 1 is seen.
Pathological examination (× 400) after Fig. 1 HE dyeing
A:Blank group B:Model group C:Positive drug group D:High dose group E:Middle dose group F:Low dose group
Analgesic activities, make acetic acid induced mice pain model, and writhing response occurs in mouse in 15 min after observation injection acetic acid,
Compare the analgesic activity of Chinese medicine composition.As a result Chinese medicine composition PTCA or and STENTS is shown, is made playing obvious antigout nephrosis
With gouty nephropathy etc., can be reduced cause writhing number of times and the reaction of pain simultaneously, with preferable analgesic activity.
By above-mentioned experimental result, the gouty nephropathy Chinese medicine composition can effectively antagonize mice pain caused by acetic acid.
Gouty nephropathy Chinese medicine composition of the present invention is to the Neurological deficits after cerebral ischemia-reperfusion injury in rats treatment
Each group rat recovers clear-headed in the min of Post operation 30 ~ 40, and body indices are gradually normal.The equal impassivity work(of sham-operation group
The neurologic impairment performance of significantly different degree is presented in different time group for energy defective symptom, model group, is such as in left limb hemiplegia
State；Topple over or rotate to the left during walking；Loop carry tail it is hanging when, forelimb is in symmetry shape, receives in left fore, is close to the wall of the chest,
Contralateral limbs reactivity reduction, Ipsilateral limb is reactionless.And significantly different degree is presented after being treated through various dose composition group
Neurologic impairment after repair performance；Wherein high dose group has pole significant difference compared with than model group after 24h（P<0.01）,
In, low dose group is after 24h compared with than model group, there were significant differences（P<0.05）, 7d, high-dose therapy group after cerebral ischemia re-pouring
The sign of rat obstacle recovers more satisfactory.As a result it see the table below.
By above-mentioned experimental result, said composition can adequately protect cerebral apoplexy nerve, to cerebral arterial thrombosis have control
Therapeutic effect.
Claims (8)
1. a kind of gouty nephropathy Chinese medicine composition, it is characterized in that:Its composition includes:Salt processs plantain seed, the root bark of shaggy-fruited dittany, coix seed, honeybee
Glue, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae, the parts by weight that described salt processs plantain seed are 15-20, described
The parts by weight of the root bark of shaggy-fruited dittany are 10-15, and the parts by weight of described coix seed are 25-30, and the parts by weight of described propolis are
0.3-0.5, the parts by weight of described desmodium are 35-40, and the parts by weight of described carrot skin are 70-90, described
The parts by weight of giant knotweed are 10-12, and the parts by weight of the described life Radix Astragali are 10-15, and the parts by weight of described radix cyathulae are
6-7。
2. gouty nephropathy Chinese medicine composition according to claim 1, it is characterized in that:Described salt processs the weight of plantain seed
Number is 15, and the parts by weight of the described root bark of shaggy-fruited dittany are 10, and the parts by weight of described coix seed are 25, the weight of described propolis
It is 0.3 to measure number, and the parts by weight of described desmodium are 35, and the parts by weight of described carrot skin are 70, described tiger
The parts by weight of cane are 10, and the parts by weight of the described life Radix Astragali are 10, and the parts by weight of described radix cyathulae are 6.
3. gouty nephropathy Chinese medicine composition according to claim 1, it is characterized in that:Described salt processs the weight of plantain seed
Number is 20, and the parts by weight of the described root bark of shaggy-fruited dittany are 15, and the parts by weight of described coix seed are 30, the weight of described propolis
It is 0.5 to measure number, and the parts by weight of described desmodium are 40, and the parts by weight of described carrot skin are 90, described giant knotweed
Parts by weight be 12, the parts by weight of the described life Radix Astragali are 15, and the parts by weight of described radix cyathulae are 7.
4. gouty nephropathy Chinese medicine composition according to claim 1, it is characterized in that:Described salt processs the weight of plantain seed
Number is 18, and the parts by weight of the described root bark of shaggy-fruited dittany are 12, and the parts by weight of described coix seed are 28, the weight of described propolis
It is 0.4 to measure number, and the parts by weight of described desmodium are 38, and the parts by weight of described carrot skin are 75, described tiger
The parts by weight of cane are 11, and the parts by weight of the described life Radix Astragali are 11, and the parts by weight of described radix cyathulae are 7.
5. a kind of preparation method of gouty nephropathy Chinese medicine composition, it is characterized in that:Weigh above-mentioned salt and process plantain seed, the root bark of shaggy-fruited dittany, the heart of a lotus seed
The seed of jog's tears, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, then cross 40-70 mesh sieves
Son, plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, radix cyathulae are processed by the salt after crushing
It is sufficiently mixed and mixed powder is made, soaked in mixed powder after 2-3h, water needs foam mixed powder, decoct 2-4 times, often
Secondary 1-2h, pours out filtering, is sufficiently mixed, merging filtrate, is concentrated into 100ml, standby.
6. the preparation method of gouty nephropathy Chinese medicine composition according to claim 5, it is characterized in that:Weigh salt and process Chinese herbaceous peony
Son, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, so
70 mesh sieve are crossed afterwards, and the salt after crushing is processed into plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, raw Huang
Stilbene, radix cyathulae, which are sufficiently mixed, is made mixed powder, is soaked in mixed powder after 3h, and water needs foam mixed powder, decocts 4
Secondary, each 2h pours out filtering, is sufficiently mixed, merging filtrate, is concentrated into 100ml, standby.
7. the preparation method of gouty nephropathy Chinese medicine composition according to claim 5, it is characterized in that:Weigh salt and process Chinese herbaceous peony
Son, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, so
40 mesh sieve are crossed afterwards, and the salt after crushing is processed into plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, raw Huang
Stilbene, radix cyathulae, which are sufficiently mixed, is made mixed powder, is soaked in mixed powder after 2h, and water needs foam mixed powder, decocts 2
Secondary, each 1h pours out filtering, is sufficiently mixed, merging filtrate, is concentrated into 100ml, standby.
8. the preparation method of gouty nephropathy Chinese medicine composition according to claim 5, it is characterized in that:Weigh salt and process Chinese herbaceous peony
Son, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, the raw Radix Astragali, the parts by weight of radix cyathulae are crushed respectively, so
60 mesh sieve are crossed afterwards, and the salt after crushing is processed into plantain seed, the root bark of shaggy-fruited dittany, coix seed, propolis, desmodium, carrot skin, giant knotweed, raw Huang
Stilbene, radix cyathulae, which are sufficiently mixed, is made mixed powder, is soaked in mixed powder after 4h, and water needs foam mixed powder, decocts 3
Secondary, each 2h pours out filtering, is sufficiently mixed, merging filtrate, is concentrated into 100ml, standby.
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| CN114306523A (en) * | 2021-12-20 | 2022-04-12 | 安徽九洲方圆制药有限公司 | Traditional Chinese medicine composition for treating gout and nephropathy |
| CN116270952A (en) * | 2023-03-21 | 2023-06-23 | 佳木斯大学 | Extract for relieving gout and extraction method and application thereof |
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| CN104825938A (en) * | 2015-05-18 | 2015-08-12 | 张仙娥 | Traditional Chinese medicine composition for treating gout |
| CN105287748A (en) * | 2015-12-10 | 2016-02-03 | 高京宏 | Traditional Chinese medicine preparation for treating hyperuricemia and preparation method thereof |
| CN105497701A (en) * | 2016-01-16 | 2016-04-20 | 杜志政 | Natural medicine for treating gout diseases and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825938A (en) * | 2015-05-18 | 2015-08-12 | 张仙娥 | Traditional Chinese medicine composition for treating gout |
| CN105287748A (en) * | 2015-12-10 | 2016-02-03 | 高京宏 | Traditional Chinese medicine preparation for treating hyperuricemia and preparation method thereof |
| CN105497701A (en) * | 2016-01-16 | 2016-04-20 | 杜志政 | Natural medicine for treating gout diseases and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114306523A (en) * | 2021-12-20 | 2022-04-12 | 安徽九洲方圆制药有限公司 | Traditional Chinese medicine composition for treating gout and nephropathy |
| CN116270952A (en) * | 2023-03-21 | 2023-06-23 | 佳木斯大学 | Extract for relieving gout and extraction method and application thereof |
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