CN107157865A - A kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics - Google Patents
A kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics Download PDFInfo
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- CN107157865A CN107157865A CN201710613348.1A CN201710613348A CN107157865A CN 107157865 A CN107157865 A CN 107157865A CN 201710613348 A CN201710613348 A CN 201710613348A CN 107157865 A CN107157865 A CN 107157865A
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- active peptides
- gadol extract
- wrinkle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention belongs to cosmetic technical field, disclose a kind of anti-wrinkle combined containing gadol extract and active peptides and repair cosmetics, the problem of anti-wrinkle repair ability is poor is there is for solving existing cosmetics.Component of the present invention and weight percentages are：Gadol extract 0.01 0.50%, active peptides combination 1.00 10.0%, excipient matrix 89.5 98.99%.The gadol extract and active peptides that the anti-wrinkle combined containing gadol extract and active peptides that the present invention is provided is repaired in cosmetics, which are combined, can improve glial growth factor in skin (KGF 2) content, improve the activity of Skin Cell, and then epidermal cell division renewal speed is improved, finally realize the purpose that anti-wrinkle is repaired.
Description
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of containing dispelling that gadol extract and active peptides are combined
Wrinkle repairs cosmetics.
Background technology
As the improvement of people's living standards, people increasingly pay attention to beauty and health care, freckle, chloasma, butterfly macules, generally
It is long facial in people, not only influence attractive in appearance, and many worries are brought to patient.Related medicine species is various, has
Freezing, medicine point coating, " changing skin ", common laser method etc., most of traditional treatment methods have many side effects, hold
Easily bring scar and pigment to react etc., these reactions sometimes remain serious, Just because of this, and people never have stopping and found
A kind of more satisfied treatment method.The high cost brought in face of instrument treatment, medicine point coating is received by ordinary consumer,
Medicine point coating is generally applied to face using pure Chinese medicine cream drug or pure Western medicine medicine, but often therapeutic effect it is undesirable,
Easily bounce-back, makes consumer disappointed, sorry, so that existing cosmetics have the problem of anti-wrinkle repair ability is poor.
The content of the invention
The present invention has the problem of anti-wrinkle repair ability is poor to solve existing cosmetics, and provides a kind of containing rhodiola root
Extract and the anti-wrinkle of active peptides combination repair cosmetics.
To solve technical problem, the technical solution adopted in the present invention is：
A kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics, it is characterised in that component and group
Part percentage by weight is：
Gadol extract 0.01-0.50%
Active peptides combine 1.00-10.0%
Excipient matrix 89.5-98.99%.
The active peptides combination is by water, glycerine, 1,2- pentanediols, pungent glycol, Argireline, pentapeptide -3, palm
Acyl hexapeptide -12, palmityl tetrapeptide -7, the citrulling of tripeptides -10 are constituted.
The component and its percentage by weight of active peptides combination be：Water is that 84.68-94.468%, glycerine are 2.0-
8.0%th, 1,2- pentanediols are that 3.0-6.0%, pungent glycol are that 0.5-1.0%, Argireline are 0.01-0.1%, pentapeptide -3
It is that 0.001-0.01%, palmityl tetrapeptide -7 are 0.001-0.01%, the melon of tripeptides -10 for 0.01-0.1%, palmityl hexapeptide -12
Propylhomoserin is 0.01-0.1%.Pentapeptide -3 can promote the synthesis of collagen and elastic veneer in skin corium, therefore, it is possible to enter one
Step improves the function of anti-wrinkle.
The mass ratio for stating rhodioside in gadol extract is 2.0-5.0%；Active component in gadol extract
For rhodioside.Active component rhodioside in gadol extract with delaying cell aging, can improve internal SOD work
Property, suppress the formation of cell lipofuscin and active oxygen.Strengthen the metabolism and synthesis of cell, the vigor of cell is improved, so as to reach
To the effect of anti-wrinkle skin makeup.During extraction, removed by calcium hydroxide precipitation in extract in tannin, citric acid and mistake
Extract is obtained after filter, drying.
The excipient matrix is water, emulsifying agent, emollient, NMF, polyalcohol, thickener, pH adjusting agent, essence or water
One or more combinations in soluble macromolecular.
Skin ageing produces the activity decrease that the topmost reason of wrinkle is Skin Cell, causes skin surface cell new city
Accretion rate slows down.Skin surface is cuticula, and cuticula is as formed by being moved up pedestal cell division, to work as basal cell
Division is formed after neoblast, and these new cells are gradually pushed to epidermis, and because the moisture of epiderm skin is distributed comparatively fast, formation does not have
Nucleolate flat dead cell, and it is layer upon layer of be deposited in skin surface, here it is cuticula, when people is young,
The metabolism of Skin Cell is vigorous, and the activity of cell is strong, and value-added speed is also fast, therefore the Skin Cell constantly moved up is continuous
Death, forms new horn cell, goes to substitute original outmoded horn cell, so the skin surface of people is continuously available more
Newly, therefore soft and moist, fine and smooth and high resilience is remained.But with advancing age, with age, Skin Cell
Activity decrease, cell propagation weakens, then the horn cell that those are deposited in top layer is just difficult for drop-off.In skin surface constantly
Thicken, the stimulation such as cuticula is constantly exposed to wind and rain in addition, the sun shines causes skin water shortage, flexibility worse and worse, finally
The intensity and flexibility decrease of skin, occur in that wrinkle.Therefore, for internal cause, skin cytoactive declines in the appearance of wrinkle
It is caused.
Gadol extract and the active peptides combination of the present invention can improve glial growth factor (KGF- in skin
2) content, improves the activity of Skin Cell, and then improves epidermal cell division renewal speed, finally realizes the mesh that anti-wrinkle is repaired
's.
The anti-wrinkle of the present invention is repaired cosmetics and made using following technique：
1. the modulation of oil phase：Oil phase component is added in beaker, 10- is stirred with 200-300r/min rotating speed with agitator
After 15min, it is seen that oil phase component is uniformly dissolved；
2. the modulation of aqueous phase：Hydrophilic composition such as gadol extract, polyalcohol, NMF, thickener etc. are added and gone
Stirred in ionized water with agitator with 300-400r/min rotating speed after 10-15min, it is seen that water phase components are uniformly dissolved.
3. emulsify：After the aqueous phase being uniformly dissolved and oil phase are mixed, stirred with agitator with 300-400r/min rotating speed
After 3-5min, with homogenizer with 2000r/min speed homogeneous 1-2min.
4. PH conditioning agents adjust pH value to 5.5~6.5, then add active peptides combination, essence, after stirring, go out
Material, produces product.
Compared with prior art, the invention has the advantages that：
The anti-wrinkle combined containing gadol extract and active peptides that the present invention is provided is repaired the rhodiola root in cosmetics and carried
Glial growth factor in skin (KGF-2) content can be improved by taking thing and active peptides to combine, and improve Skin Cell
Activity, and then epidermal cell division renewal speed is improved, finally realize the purpose that anti-wrinkle is repaired.
Non-toxic and side effect of the invention, such as allergy, situations such as stimulating and be rubescent, and suitable for the skin of the various colours of skin
Skin.
The manufacture craft of the present invention is made using cold with technique, ensure that active peptides, gadol extract etc.
The activity of functional component, it is ensured that product quality and effect.
Embodiment
With reference to embodiment, the invention will be further described, and described embodiment is only a part of the invention
Embodiment, is not whole embodiments.Based on the embodiment in the present invention, one of ordinary skill in the art is not making
Other embodiments used obtained under the premise of creative work, belong to protection scope of the present invention.
Embodiment one
The anti-wrinkle combined containing gadol extract and active peptides of the present embodiment repairs cosmetics, component and component weight
Percentage is：Gadol extract 0.01%, active peptides combination 1.00% and excipient matrix 98.99%；Wherein active peptides
The component and its percentage by weight of combination be：Water is that 90.900%, glycerine is that 3.05%, 1,2- pentanediols are that 5%, pungent glycol is
1.0%th, Argireline is that 0.01%, pentapeptide -3 is that 0.01%, palmityl hexapeptide -12 is 0.01%, palmityl tetrapeptide -7
It is 0.01% for the 0.01%, citrulling of tripeptides -10.
Embodiment two
The anti-wrinkle combined containing gadol extract and active peptides of the present embodiment repairs cosmetics, component and component weight
Percentage is：Gadol extract 0.05%, active peptides combination 5.00% and excipient matrix 94.95%；Wherein active peptides
The component and its percentage by weight of combination be：Water is that 86.795%, glycerine is that 8%, 1,2- pentanediols are that 4.5%, pungent glycol is
0.5%th, Argireline is that 0.03%, pentapeptide -3 is that 0.06%, palmityl hexapeptide -12 is 0.005%, palmityl tetrapeptide -7
It is 0.1% for the 0.01%, citrulling of tripeptides -10.
Embodiment three
The anti-wrinkle combined containing gadol extract and active peptides of the present embodiment repairs cosmetics, component and component weight
Percentage is：Gadol extract 0.50%, active peptides combination 1.00% and excipient matrix 89.5%；Wherein active peptides group
The component and its percentage by weight of conjunction be：Water is that 91.18%, glycerine is that 2.0%, 1,2- pentanediols are that 6.0%, pungent glycol is
0.7%th, Argireline is that 0.02%, pentapeptide -3 is that 0.03%, palmityl hexapeptide -12 is 0.003%, palmityl tetrapeptide -7
It is 0.06% for the 0.007%, citrulling of tripeptides -10.
Example IV
The anti-wrinkle combined containing gadol extract and active peptides of the present embodiment repairs cosmetics, component and component weight
Percentage is：Gadol extract 0.1%, active peptides combination 5% and excipient matrix 94.9%；Wherein active peptides are combined
Component and its percentage by weight are：Water is that 89.018%, glycerine is that 7.0%, 1,2- pentanediols are that 3.0%, pungent glycol is
0.8%th, Argireline is that 0.05%, pentapeptide -3 is that 0.04%, palmityl hexapeptide -12 is 0.007%, palmityl tetrapeptide -7
It is 0.08% for the 0.005%, citrulling of tripeptides -10.
Embodiment five
The anti-wrinkle combined containing gadol extract and active peptides of the present embodiment repairs cosmetics, component and component weight
Percentage is：Gadol extract 0.4%, active peptides combination 7.6% and excipient matrix 92%；Wherein active peptides are combined
Component and its percentage by weight are：Water is that 94.468%, glycerine is that 2.0%, 1,2- pentanediols are that 3.0%, pungent glycol is
0.5%th, Argireline is that 0.01%, pentapeptide -3 is that 0.01%, palmityl hexapeptide -12 is 0.001%, palmityl tetrapeptide -7
It is 0.01% for the 0.001%, citrulling of tripeptides -10.
Embodiment six
Above-described embodiment one into embodiment five any embodiment basis on, excipient matrix be water, emulsifying agent, profit
One or more combinations in skin agent, NMF, polyalcohol, thickener, pH adjusting agent, essence or water soluble polymer.
Embodiment seven
Above-described embodiment one into embodiment six any embodiment basis on, gadol extract is rhodioside
Gadol extract of the content 2.0%.
Embodiment eight
Above-described embodiment one into embodiment six any embodiment basis on, gadol extract is rhodioside
Gadol extract of the content 5.0%.
Embodiment nine
Above-described embodiment one into embodiment six any embodiment basis on, gadol extract is rhodioside
Gadol extract of the content 3.2%.
Embodiment ten
Above-described embodiment one into embodiment six any embodiment basis on, gadol extract is rhodioside
Gadol extract of the content 4.0%.
Embodiment 11
Above-described embodiment one into embodiment six any embodiment basis on, gadol extract is rhodioside
Gadol extract of the content 2.5%.
Case 1：
Certain is thanked, female, 50 years old, there is more wrinkle, and skin Quality Down in forehead, in continuously using the present embodiment 3
Proportioning whitening cosmetics after 30 days, wrinkle substantially attenuates, it is continuous using 70 days after, wrinkle is almost wholly absent,
Skin quality is obviously improved, and does not have skin adverse reaction during use.
Case 2：
Liao, female, 45 years old, complexion was intensely dark, and crow's feet is more, the change of the proportioning in continuously using the present embodiment 1
After cosmetic 15 days, crow's feet is tapered, and after continuous use 80 days, crow's feet is wholly absent, and the colour of skin is also become by inclined blackyellow
For inclined yellow-white, and skin also becomes more to compact, and does not have skin adverse reaction during use.
Case 3：
Zheng, female, 31 years old, because there is serious striae of pregnancy in postpartum, the proportioning in continuously using the present embodiment eight
After whitening cosmetics 20 days, skin pore becomes to compact, and striae of pregnancy is tapered, after continuous use 60 days, striae of pregnancy
Almost it is wholly absent, skin quality is obviously improved, compacts flexible, and does not have skin adverse reaction during use.
The anti-wrinkle of the present invention is repaired cosmetics and made using following technique：By except active peptides component and essence remaining
Each component is divided into oil phase (being not readily dissolved in water) and aqueous phase (soluble in water), then carries out as follows；
1. the modulation of oil phase：Oil phase component is added in beaker, stirred with agitator with 200-300r/min rotating speed
After 10-15min, it is seen that oil phase component is uniformly dissolved.
2. the modulation of aqueous phase：Hydrophilic composition such as gadol extract, polyalcohol, NMF, thickener etc. are added and gone
Stirred in ionized water with agitator with 300-400r/min rotating speed after 10-15min, it is seen that water phase components are uniformly dissolved.
3. emulsify：After the aqueous phase being uniformly dissolved and oil phase are mixed, stirred with agitator with 300-400r/min rotating speed
After 3-5min, with homogenizer with 2000r/min speed homogeneous 1-2min.
4. PH conditioning agents adjust pH value to 5.5~6.5, then add active peptides combination, essence, after stirring, go out
Material, produces product.
Claims (6)
1. a kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics, it is characterised in that component and component
Percentage by weight is：
Gadol extract 0.01-0.50%
Active peptides combine 1.00-10.0%
Excipient matrix 89.5-98.99%.
2. the anti-wrinkle according to claim 1 combined containing gadol extract and active peptides repairs cosmetics, its feature
It is, the active peptides combination is by water, glycerine, 1,2- pentanediols, pungent glycol, Argireline, pentapeptide -3, palmityl six
Peptide -12, palmityl tetrapeptide -7, the citrulling of tripeptides -10 are constituted.
3. the anti-wrinkle according to claim 2 combined containing gadol extract and active peptides repairs cosmetics, its feature
It is, the component and its percentage by weight of the active peptides combination are：Water is that 84.68-94.468%, glycerine are 2.0-
8.0%th, 1,2- pentanediols are that 3.0-6.0%, pungent glycol are that 0.5-1.0%, Argireline are 0.01-0.1%, pentapeptide -3
It is that 0.001-0.01%, palmityl tetrapeptide -7 are 0.001-0.01%, the melon of tripeptides -10 for 0.01-0.1%, palmityl hexapeptide -12
Propylhomoserin is 0.01-0.1%.
4. the anti-wrinkle according to claim 1 combined containing gadol extract and active peptides repairs cosmetics, its feature
It is, the mass ratio of rhodioside is 2.0-5.0% in the gadol extract；Active component in gadol extract is
Rhodioside.
5. the anti-wrinkle according to claim 1 combined containing gadol extract and active peptides repairs cosmetics, its feature
It is, the excipient matrix is water, emulsifying agent, emollient, NMF, polyalcohol, thickener, pH adjusting agent, essence or water-soluble
One or more combinations in property macromolecule.
6. a kind of anti-wrinkle combined containing gadol extract and active peptides repairs the preparation method of cosmetics, it is characterised in that
Comprise the following steps：
1. the modulation of oil phase：Oil phase component is added in beaker, 10- is stirred with 200-300r/min rotating speed with agitator
After 15min, it is seen that oil phase component is uniformly dissolved；
2. the modulation of aqueous phase：Hydrophilic composition such as gadol extract, polyalcohol, NMF, thickener etc. are added deionization
Stirred in water with agitator with 300-400r/min rotating speed after 10-15min, water phase components are uniformly dissolved；
3. emulsify：After the aqueous phase being uniformly dissolved and oil phase are mixed, 3- is stirred with 300-400r/min rotating speed with agitator
After 5min, with homogenizer with 2000r/min speed homogeneous 1-2min；
4. PH conditioning agents adjust pH value to 5.5~6.5, then add active peptides combination, essence, after stirring, discharging, i.e.,
Obtain product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710613348.1A CN107157865A (en) | 2017-07-25 | 2017-07-25 | A kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710613348.1A CN107157865A (en) | 2017-07-25 | 2017-07-25 | A kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107157865A true CN107157865A (en) | 2017-09-15 |
Family
ID=59817483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710613348.1A Pending CN107157865A (en) | 2017-07-25 | 2017-07-25 | A kind of anti-wrinkle combined containing gadol extract and active peptides repairs cosmetics |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109939026A (en) * | 2017-12-20 | 2019-06-28 | 隐纱化妆品有限公司 | Anti aging effect composition containing cordyceps sinensis |
| CN109984952A (en) * | 2017-12-29 | 2019-07-09 | 广州佳洁化妆品有限公司 | A kind of Essence and preparation method of the compounding removing wrinkle and resisting aging containing a variety of small-molecule peptides |
| CN111494224A (en) * | 2020-06-16 | 2020-08-07 | 四川天晟制药有限公司 | Whitening and spot-fading composition, skin care product and preparation method thereof |
| CN111714400A (en) * | 2020-07-27 | 2020-09-29 | 广东真丽斯化妆品有限公司 | Cosmetic with anti-aging and repairing effects and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104490732A (en) * | 2014-12-10 | 2015-04-08 | 内蒙古天奇生物科技有限公司 | Anti-aging scale collagen polypeptide facial mask and preparation method thereof |
| CN104523449A (en) * | 2015-01-08 | 2015-04-22 | 上海圣婕化妆品有限公司 | Anti-aging polypeptide compound and application thereof |
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2017
- 2017-07-25 CN CN201710613348.1A patent/CN107157865A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104490732A (en) * | 2014-12-10 | 2015-04-08 | 内蒙古天奇生物科技有限公司 | Anti-aging scale collagen polypeptide facial mask and preparation method thereof |
| CN104523449A (en) * | 2015-01-08 | 2015-04-22 | 上海圣婕化妆品有限公司 | Anti-aging polypeptide compound and application thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109939026A (en) * | 2017-12-20 | 2019-06-28 | 隐纱化妆品有限公司 | Anti aging effect composition containing cordyceps sinensis |
| CN109984952A (en) * | 2017-12-29 | 2019-07-09 | 广州佳洁化妆品有限公司 | A kind of Essence and preparation method of the compounding removing wrinkle and resisting aging containing a variety of small-molecule peptides |
| CN111494224A (en) * | 2020-06-16 | 2020-08-07 | 四川天晟制药有限公司 | Whitening and spot-fading composition, skin care product and preparation method thereof |
| CN111714400A (en) * | 2020-07-27 | 2020-09-29 | 广东真丽斯化妆品有限公司 | Cosmetic with anti-aging and repairing effects and preparation method thereof |
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Application publication date: 20170915 |