CN107157507A - A kind of CT digital subtraction angiographys imaging system and method - Google Patents
A kind of CT digital subtraction angiographys imaging system and method Download PDFInfo
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- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
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Abstract
The invention discloses a kind of CT digital subtraction angiographys (CT DSA) imaging system and method, it is made up of x-ray generator, energy-resolved photon counting detector, CT image reconstruction units, digital image subtraction unit, image storage transmission with display unit, examination couch, frame and controller.X-ray source produces continuum x-ray and human body is quickly scanned；The detection of energy-resolved photon counting detector is differentiated and counted to its energy through the x photons after human body；The signal of CT image reconstruction unit collecting energy resolving photons digital detector output, two groups of transmission projection datas in high-energy area and low energy area are formed, tomographic image reconstructing is carried out respectively to the data for projection of height energy range using analytic reconstruction algorithm or statistics algorithm for reconstructing；Digital image subtraction unit applies different weights to the tomographic reconstruction images of high and low two energy range of each same scan position, and progress subtracts shadow and calculates acquisition CT digital subtraction angiography images.
Description
Technical field：
The present invention relates to for medical x-ray imaging system and method, be exactly to be related to a kind of CT Digital Subtractions blood
Pipe radiography (computed tomography digital subtraction angiography, CT DSA) imaging system with
Method, the effective means of the high-quality imaging of low dosage is provided for the diagnosis and treatment of vascular lesion.
Background technology：
Vascular diseases are to cause one of global main causes of death, obtain accurate patient vessel's image and are examined for clinic
Treat significant.Angiographic imaging (DSA) is large-scale real-time imaging diagnostic device, especially in sides such as coronarography diagnosis
Face is indispensable equipment, is that the implementation of the main dependence of interventional minimally-invasive operation is image-guided while being also the platform of PCI
Equipment.It is mainly used in percutaneous transluminal coronary stent implantation, minimally invasive valve implantation, tumor intervention therapeutic, cerebrovascular malformation and aneurysm
PCI, interventional therapy for uterine fibroids and arteria renalis chemical sympathectomy treatment hypertension in terms of, while being also existing
The necessary equipment of generation hybridization operating room.But what this method was obtained is two dimensional image, image medium vessels exists overlapping, is unfavorable for facing
Bed diagnosis and treatment.Three-dimensional DSA image can effectively solve the above problems, it is possible to use dual intensity CT imagings (double source dual intensity CT or single sources
High-voltage high-speed switching CT imaging techniques) realize, but the structure of this two kind equipment and control obviously become extremely complex, and
Need to double expose for same position, so that the dose of radiation received when considerably increasing imaging patients；In addition, for
Single source high-voltage high-speed switches CT imaging techniques, and the time interval of double exposure is although short, but may have motion artifacts.
Using photon counting detector, the interval photon counting of high and low two energy, energy can be obtained by single exposure
The interval threshold value of amount can flexibly be set.When dual intensity CT is imaged, it is imaged using two kinds of different tube voltages, equipment is complicated, energy
Spectrum have differences with it is overlapping, so as to reduce the quality of image.It is different from dual intensity CT imagings, obtained based on photon counting detector
The interval photon counting of high and low energy energy envelope is not present, be conducive to improving picture quality, by identical image space
The faultage image of high and low energy, which is weighted, subtracts shadow, it is possible to obtain the tomography subtraction image at the position.Therefore, it is this to set
It is standby simple, exposure dose is effectively reduced, motion artifacts are eliminated, picture quality can be improved；By post processing of image, it can obtain
The 3-D view of blood vessel, facility is provided for clinic diagnosis.Therefore the present invention is significant to clinic diagnosis.
The content of the invention：
The present invention provides a kind of CT digital subtraction angiographys imaging system and method, effectively reduces exposure dose, it is to avoid
Motion artifacts, meet the demand of the high-quality CT imagings of clinical low dosage.
This invention takes following technical scheme：A kind of CT digital subtraction angiographys imaging system and method, are penetrated by x
Line generator, energy-resolved photon counting detector, CT image reconstruction units, digital image subtraction unit, image storage transmission
Constituted with display unit, examination couch, frame and controller, the x-ray generator is used for producing x-ray；The energy resolution
Photon counting detector detection is through the x photons after human body, and the energy of the x photons to detecting is differentiated and counted；It is described
The signal of CT image reconstruction unit collecting energy resolving photons digital detector output, forms the two of high-energy area and low energy area
Group transmission projection data, is distinguished the data for projection of high and low two energy range using analytic reconstruction algorithm or statistics algorithm for reconstructing
Carry out tomographic image reconstructing；The digital image subtraction unit is to the disconnected of high and low two energy range of each same scan position
Layer reconstruction image applies different weights, and progress subtracts shadow and calculates acquisition CT digital subtraction angiography images；Described image is stored
Transmission receives the image from digital image subtraction unit with display unit, is stored and is shown, and can pass through network and its
Its equipment carries out data communication；The examination couch is used for carrying patient；The frame is used for controlling the pose of x-ray generator；
Described control unit is x-ray generator, energy-resolved photon counting detector, CT image reconstruction units, digital image subtraction
Unit, image storage transmission and display unit, examination couch, frame provide control signal and communication.
The x-ray generator is used for producing continuum x-ray, and using the harmful Lower Energy X-ray of filter removal,
Then throw and shine the subject containing contrast agent.
The energy-resolved photon counting detector detection x photons formation electric signal, is corrected to signal and amplitude is discriminated
Not, high and low two energy range is divided the signal into according to energy threshold to be counted.
The signal of CT image reconstruction units collecting energy resolving photon digital detector output, formed high-energy area and
Two groups of transmission projection datas in low energy area, the projection using analytic reconstruction algorithm or statistics algorithm for reconstructing to high and low energy range
Data carry out tomographic image reconstructing respectively.
The digital image subtraction unit receives the image of high and low two energy range of CT image reconstruction units transmission, right
The image I of high and low two energy range from same position of faultH、ILApply different weight coefficient α, β, progress subtracts shadow calculating
CT digital subtraction angiography image I are can obtain, shown in such as formula (1).
I=α IH-βIL (1)
Described image storage transmission and display unit receive the image sent from digital image subtraction unit, and storage is to depositing
In storage media, it is shown on display, and data communication can be carried out by network and miscellaneous equipment.
The examination couch can do top to bottom, left and right, front and rear motion, the need for meeting scanning imagery.
The frame is used for holding x-ray generator and detector, x-ray generator is located at examination couch two with detector
Side and rotated around examination couch.
Described control unit gives x-ray generator to provide control signal, come control the intensity of x-ray, ray to produce and in
Only；Control signal is provided for examination couch, the pose of examination couch is adjusted；Control letter is provided for energy-resolved photon counting detector
Number, the execution of control data collection；Control signal is provided for frame, the motion of frame is controlled；There is provided for CT image reconstruction units
Control signal, the receiving of control signal and the formation of high and low energy range faultage image；Control is provided for digital image subtraction unit
Signal processed, the formation for controlling CT DSA images；Control signal is provided for image storage transmission and display unit, depositing for image is controlled
Storage, transmission and display.
The present invention utilizes photon counting detector, and the interval photon of high and low two energy can be obtained by single exposure
Count, the interval threshold value of energy can flexibly be set.When dual intensity CT is imaged, it is imaged using two kinds of different tube voltages, equipment
Complexity, power spectrum have differences with it is overlapping, so as to reduce picture quality.It is different from dual intensity CT imagings, based on photon counting detection
Energy envelope is not present in the photon counting in the high and low energy interval that device is obtained, and is conducive to improving picture quality, by identical into image position
The faultage image for the high and low energy put, which is weighted, subtracts shadow, it is possible to obtain the tomography subtraction image at the position.Therefore, with
Dual intensity CT blood vessel imagings are compared, and the system structure is relatively easy, are effectively reduced exposure dose, eliminate motion artifacts, improve figure
As quality；By post processing of image, clearly blood vessel 3-D view is can obtain, more effective diagnosis and treatment means are provided for clinic.
Brief description of the drawings：
Fig. 1 is a kind of CT digital subtraction angiographys imaging system block diagram.
Embodiment：
It refer to shown in Fig. 1, a kind of CT digital subtraction angiographys (computed tomographic of the invention
Digital subtraction angiography, CT DSA) imaging system is by x-ray generator, energy-resolved photon counting
Detector, CT image reconstruction units, digital image subtraction unit, image storage transmission and display unit, examination couch, frame and control
Device processed is constituted.X-ray source produces continuum x-ray；X-ray source is to checking that target is quickly scanned；Energy resolving photon
Digital detector detection is differentiated and counted to the x photon energies detected through the x photons after human body；CT image reconstructions
The signal of unit collecting energy resolving photon digital detector output, forms two groups of transmission projections in high-energy area and low energy area
Data, tomograph is carried out using analytic reconstruction algorithm or statistics algorithm for reconstructing respectively to the data for projection of high and low two energy range
As rebuilding；Digital image subtraction unit applies to the tomographic reconstruction images of high and low two energy range of each same scan position
Different weights, progress subtracts shadow and calculates acquisition CT digital subtraction angiography images.
Exposure can obtain the interval photon counting of high and low energy simultaneously to the system every time, and in the absence of energy envelope problem,
The faultage image of the high and low energy of identical image space is weighted and subtracts shadow, it is possible to obtains the tomography at the position and subtracts shadow
Image.Therefore, compared with dual intensity CT blood vessel imagings, the system structure is relatively easy, is effectively reduced exposure dose, eliminates motion
Artifact, improves picture quality, and more effectively accurate diagnosis and treatment means are provided for clinic.
The embodiment of the present invention is described in detail below by one embodiment.
Embodiment 1：Cardiovascular CT DSA imagings
(1) subject is placed on examination couch, adjusts its pose；
(2) according to the energy threshold of the property of contrast agent setting photon counting detector, and high and low energy range image
Weight α and β；
(3) the system is started under the control of the control unit, the x-ray produced using x-ray generator is entered to subject
The quick scanning of row, transmission x-ray is received by energy-resolved photon counting detector and divides energy range to be counted；CT image reconstructions
The signal of unit collecting energy resolving photon digital detector output, forms two groups of transmission projections in high-energy area and low energy area
Data, faultage image weight is carried out using analytic reconstruction algorithm or statistics algorithm for reconstructing respectively to the data for projection of high and low energy range
Build；Digital image subtraction unit receives the image of high and low two energy range of CT image reconstruction units transmission, to from same disconnected
The image I of high and low two energy range of layer positionHAnd ILApply different weight coefficient α and β, progress subtracts shadow and calculates i.e. available
CT DSA image I=α IH-βIL；CT DSA images are sent to image storage and transmitted and display unit, the storage of progress image,
Transmission and display.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, some improvement can also be made under the premise without departing from the principles of the invention, and these improvement also should be regarded as the present invention's
Protection domain.
Claims (6)
1. a kind of CT digital subtraction angiographys (computed tomographic digital subtraction
Angiography, CT DSA) imaging system and method, the system by x-ray generator, energy-resolved photon counting detector,
CT image reconstruction units, digital image subtraction unit, image storage transmission and display unit, examination couch, frame and controller structure
Into.X-ray source produces continuum x-ray；X-ray source is to checking that target is quickly scanned；Energy-resolved photon counting is visited
Device detection is surveyed through the x photons after human body, the x photon energies detected are differentiated and counted；CT image reconstruction units are adopted
Collect the signal of energy-resolved photon counting detector output, form two groups of transmission projection datas in high-energy area and low energy area,
Faultage image weight is carried out respectively to the data for projection of high and low two energy range using analytic reconstruction algorithm or statistics algorithm for reconstructing
Build；Digital image subtraction unit applies different to the tomographic reconstruction images of high and low two energy range of each same scan position
Weight, progress subtract shadow calculate obtain CT digital subtraction angiography images.This method can avoid motion artifacts, reduce contrast agent
Consumption and dose of radiation, improve device efficiency, and more effective means are provided for the CT DSA imagings of blood vessel particularly dynamic vascular,
With important clinical value.
2. a kind of CT digital subtraction angiographys imaging system and method as claimed in claim 1, it is characterized in that：Energy resolution
Photon counting detector detection x photons formation electric signal, is corrected and amplitude discriminator to signal, according to energy threshold by signal
It is divided into high and low two energy range to be counted.
3. a kind of CT digital subtraction angiographys imaging system and method as claimed in claim 1, it is characterized in that：CT image weights
The signal of unit collecting energy resolving photon digital detector output is built, two groups of transmissions for forming high-energy area and low energy area are thrown
Shadow data, tomography is carried out using analytic reconstruction algorithm or statistics algorithm for reconstructing respectively to the data for projection of high and low two energy range
Image reconstruction.
4. a kind of CT digital subtraction angiographys imaging system and method as claimed in claim 1, it is characterized in that：Digital picture
Subtract the image that shadow unit receives high and low two energy range of CT image reconstruction units transmission, to two from same position of fault
Width image applies different weights, and progress subtracts shadow calculating and can obtain CT digital subtraction angiography images.
5. a kind of CT digital subtraction angiographys imaging system and method as claimed in claim 1, it is characterized in that：Image is stored
Transmission receives the image from the transmission of digital image subtraction unit with display unit, stores into storage medium, is shown in display
On device, and data communication can be carried out by network and miscellaneous equipment.
6. a kind of CT digital subtraction angiographys imaging system and method as claimed in claim 1, it is characterized in that：Control unit
Control signal is provided to x-ray generator, to control the intensity of x-ray, ray to produce and stop；Control letter is provided for examination couch
Number, adjust the pose of examination couch；Control signal, the execution of control data collection are provided for energy-resolved photon counting detector；
Control signal is provided for frame, the motion of frame is controlled；The receiving of control signal, control signal is provided for CT image reconstruction units
And the formation of high and low energy range faultage image；Control signal is provided for digital image subtraction unit, control CT DSA images
Formed；Control signal is provided for image storage transmission and display unit, the storage, transmission and display of image is controlled.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111093509A (en) * | 2017-09-21 | 2020-05-01 | 通用电气公司 | Energy separation in multi-energy computed tomography |
| CN111524222A (en) * | 2020-04-01 | 2020-08-11 | 北京东软医疗设备有限公司 | Image forming method, apparatus, device and storage medium |
| CN111904446A (en) * | 2020-09-11 | 2020-11-10 | 深圳先进技术研究院 | Mammary gland imaging system and imaging method thereof |
| CN112617867A (en) * | 2019-09-24 | 2021-04-09 | 西门子医疗有限公司 | Method and apparatus for creating digital subtraction angiography |
| CN112862722A (en) * | 2021-02-25 | 2021-05-28 | 清华大学 | Dual-energy X-ray subtraction method and device |
| CN114842968A (en) * | 2022-06-30 | 2022-08-02 | 北京超数时代科技有限公司 | Digital enteroscope diagnosis and treatment system based on artificial intelligence |
| CN115813419A (en) * | 2023-02-20 | 2023-03-21 | 武汉联影生命科学仪器有限公司 | Method and device for energy spectrum CT imaging and CT scanning imaging system |
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| CN104644197A (en) * | 2013-11-18 | 2015-05-27 | 三星电子株式会社 | X-ray imaging apparatus and method of controlling the same |
| CN106562797A (en) * | 2016-10-27 | 2017-04-19 | 南京航空航天大学 | System and method for single-exposure digital subtraction angiography imaging |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111093509A (en) * | 2017-09-21 | 2020-05-01 | 通用电气公司 | Energy separation in multi-energy computed tomography |
| CN111093509B (en) * | 2017-09-21 | 2023-09-12 | 通用电气公司 | Energy separation in multi-energy computed tomography |
| CN112617867A (en) * | 2019-09-24 | 2021-04-09 | 西门子医疗有限公司 | Method and apparatus for creating digital subtraction angiography |
| CN111524222A (en) * | 2020-04-01 | 2020-08-11 | 北京东软医疗设备有限公司 | Image forming method, apparatus, device and storage medium |
| CN111524222B (en) * | 2020-04-01 | 2023-08-08 | 北京东软医疗设备有限公司 | Imaging method, device, equipment and storage medium |
| CN111904446A (en) * | 2020-09-11 | 2020-11-10 | 深圳先进技术研究院 | Mammary gland imaging system and imaging method thereof |
| CN112862722A (en) * | 2021-02-25 | 2021-05-28 | 清华大学 | Dual-energy X-ray subtraction method and device |
| CN112862722B (en) * | 2021-02-25 | 2023-03-24 | 清华大学 | Dual-energy X-ray subtraction method and device |
| CN114842968A (en) * | 2022-06-30 | 2022-08-02 | 北京超数时代科技有限公司 | Digital enteroscope diagnosis and treatment system based on artificial intelligence |
| CN114842968B (en) * | 2022-06-30 | 2022-09-13 | 北京超数时代科技有限公司 | Digital enteroscope diagnosis and treatment system based on artificial intelligence |
| CN115813419A (en) * | 2023-02-20 | 2023-03-21 | 武汉联影生命科学仪器有限公司 | Method and device for energy spectrum CT imaging and CT scanning imaging system |
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