CN107096008A - One kind releive pain relieving ointment and preparation method thereof, application - Google Patents
One kind releive pain relieving ointment and preparation method thereof, application Download PDFInfo
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- CN107096008A CN107096008A CN201710244151.5A CN201710244151A CN107096008A CN 107096008 A CN107096008 A CN 107096008A CN 201710244151 A CN201710244151 A CN 201710244151A CN 107096008 A CN107096008 A CN 107096008A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/734—Alginic acid
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The present invention discloses one kind and releived pain relieving ointment, including following component：10~30 parts of glycerine, 2~8 parts of algin, 0.5~1 part of methyl salicylate, 10~20 parts of peppermint leaf oil, 5~7 parts of citronella grass oil, 4~8 parts of blue gum leaf oil, 5~20 parts of eucommia ulmoides extracts, 5~10 parts of rose oil, 3~10 parts of sandalwood oil, very heavy group of 4~10 parts of extract solution, 3~10 parts of You Jiali extract solutions, 2~8 parts of siphon extract solution, 0.5~1.5 part of Ginger P.E, 1~20 part of water, 2~5 parts of system stabilizers, 0.05~3 part of thickener, 0.1~5 part of ethanol.Formula employed in the present invention has clearing away heat to and alleviating pain, effect promoting blood circulation and removing blood stasis, from the eucommia Bark male flower Jing Guo specially treated, strengthen effect complementation of itself and other components in medicine, there is instant effect, good effect and effect uneasy to recur for obstinate grieved particularly arthritis ache, traumatic injury and the hemorrhoid for the treatment of.
Description
Technical field
The invention belongs to medical medicine technical field, and in particular to one kind is releived pain relieving ointment and preparation method thereof, purposes.
Background technology
Rhythm with life, work is constantly accelerated, and all kinds of pain class diseases are also emerged in large numbers one after another, work of particularly bending over the desk for a long time
Make or arduous work person, the sick and wounded problem such as back ache, pulled muscle, arthralgia annoyings patient, to patient just
Often life brings very big inconvenience.Currently for this illness frequently with physical treatment method, such as hot compress, toast, press
Rub, but these treatment methods take effect relatively slowly, and also method is not easy to produce secondary injury to affected part to if；In addition it is directed to
These pain patients select to use anodyne link, and anodyne is a kind of nerve anesthesia medicine, and long-term taking can be made to patient
Into larger side effect.Accordingly, it would be desirable to develop a kind of instant effect and toxic side effect is small, be difficult analgesic drug product of releiving repeatedly.
The content of the invention
Goal of the invention：Present invention aims at there is provided a kind of seeing suitable for various people in view of the shortcomings of the prior art
Effect is fast, toxic side effect is small and is difficult pain relieving ointment and preparation method thereof of releiving of recurrent exerbation, purposes.
Technical scheme：One kind of the present invention is releived pain relieving ointment, including following component：10~30 parts of glycerine, algin 2~
8 parts, 0.5~1 part of methyl salicylate, 10~20 parts of peppermint leaf oil, 5~7 parts of citronella grass oil, 4~8 parts of blue gum leaf oil, eucommia ulmoides extracts 5
~20 parts, 5~10 parts of rose oil, 3~10 parts of sandalwood oil, very heavy group of 4~10 parts of extract solution, 3~10 parts of You Jiali extract solutions,
2~8 parts of siphon extract solution, 0.5~1.5 part of Ginger P.E, 2~5 parts of tea leaf oil, 1~5 part of basil, 1~20 part of water,
2~5 parts of system stabilizers, 0.05~3 part of thickener, 0.1~5 part of ethanol, in terms of weight fraction；
The eucommia ulmoides extracts extract from eucommia Bark male flower, and its specific preparation method is as follows：
(11) take at ripe eucommia Bark male flower, 35~40 DEG C immerse mass fraction for 25wt% sodium acetate aqueous solution in 24~
36h, then takes out, and ventilation bakees drying at 45~50 DEG C, obtains bark of eucommia dried flower；
(12) obtained bark of eucommia dried flower in step (1) is smashed to pieces, and eucommia flower powder is immersed into acetic acid at 35~45 DEG C
12~24h in ethyl ester solvent, then repeatedly vacuum distillation recovered solvent after suction filtration 2~4 times, obtains one-level eucommia ulmoides extracts；
(13) 12~24h in ethanol will be immersed in one-level extract in step (2) at normal temperatures sealed environment, then repeated
Vacuum distillation recovered solvent after suction filtration 2~4 times, obtains two grades of eucommia ulmoides extracts；Two grades of eucommia ulmoides extracts deionized water rinsings
Obtain the eucommia ulmoides extracts of the present invention；
The specific preparation method of the siphon extract solution is as follows：
(21) take siphon rattan peel to be soaked in 24~36h in saturated aqueous common salt at 35~45 DEG C, then take out, 40~
Ventilation bakees drying at 55 DEG C, obtains dry siphon rattan peel；
(22) the drying siphon rattan peel obtained in step (1) is crushed, and its powder is immersed in deionized water, big fire
Boil rear small fire and decoct 3~6h, be then filtrated to get siphon rattan peel one-level extract solution；
(23) by under the siphon rattan peel one-level extract solution reduced pressure 0.002MPa~0.003MPa obtained in step (2)
Rectifying is carried out, the cut of 80~85 DEG C of boiling ranges is extracted, obtains siphon extract solution；
The system stabilizers include following component：
Further, the thickener is marine alga sodium metasilicate or plain digested tankage.
The present invention also provides the preparation method of above-mentioned pain relieving ointment of releiving, it is characterised in that specific as follows：
(31) by peppermint leaf oil, citronella grass oil, blue gum leaf oil, rose oil, tea leaf oil, basil, methyl salicylate, very heavy group
It is uniformly mixed under extract solution and sandalwood oil room temperature condition, then adds You Jiali extract solutions, siphon extract solution and life
Ginger extract continues to stir to well mixed；
(32) above-mentioned system is warming up to 35~45 DEG C and adds algin, water and thickener, continue to add after being stirred until homogeneous
Enter eucommia ulmoides extracts and ethanol, continue to stir 2~4h and system is down to room temperature in whipping process, it is rear to add glycerine and system
Stabilizer stirs 0.5~1h and obtains pain relieving ointment of releiving.
Present invention also offers above-mentioned application of the pain relieving ointment in treatment traumatic injury, painful swelling of joints medicine of releiving.
Present invention also offers above-mentioned application of the pain relieving ointment in medicine for treaching hemorrhoie of releiving.
Further, when as medicine for treaching hemorrhoie, the pain relieving ointment of releiving includes following component：28 parts of glycerine, sea
6 parts of phycocolloid, 0.8 part of methyl salicylate, 15 parts of peppermint leaf oil, 5 parts of citronella grass oil, 4 parts of blue gum leaf oil, 18 parts of eucommia ulmoides extracts, rose
8 parts of caul-fat, 4 parts of sandalwood oil, very heavy group of 8 parts of extract solution, 8 parts of You Jiali extract solutions, 3.5 parts of siphon extract solution, ginger is extracted
1 part of thing, 2 parts of tea leaf oil, 2 parts of basil, 5 parts of water, 2.5 parts of system stabilizers, 1 part of thickener, 2 parts of ethanol, with weight fraction
Meter.
Beneficial effect：(1) formula employed in the present invention has clearing away heat to and alleviating pain, effect promoting blood circulation and removing blood stasis, from process
The eucommia Bark male flower of specially treated, and two grades of extraction processes are used to it, the extract for obtaining being adapted to this pharmaceutical formulation is extracted, is improved
Medicine is releived the effect of analgesic；80~85 DEG C are obtained under reduced pressure 0.002MPa~0.003MPa by specific extraction process
The siphon extract solution of boiling range, improves efficient constituent content in drug component, improves medicine quality；(2) lead in this drug component
Cross and add special system stabilizers, improve the stability of the medicine, increase the medicine resting period, and the stabiliser system has
Nontoxic the characteristics of, do not have a negative impact to effect of drugs and patient；(3) formula of this medicine has functional diversity
The characteristics of, other curative effect medicines special can be done when adjusting each component ratio a to particular range, such as hemorrhoid treating medicine is controlled
Therapeutic effect is notable；(4) complementation of each component effect is strengthened in this medicine, for the obstinate grieved particularly arthritis ache for the treatment of, falls
Beating damage and hemorrhoid etc. has instant effect, good effect and effect uneasy to recur.
Embodiment
Technical solution of the present invention is described in detail below by embodiment, but protection scope of the present invention is not limited to
In the embodiment.
Embodiment 1：One kind is releived pain relieving ointment, including following component：10 parts of glycerine, 2 parts of algin, 0.5 part of methyl salicylate is thin
10 parts of lotus leaf oil, 5 parts of citronella grass oil, 4 parts of blue gum leaf oil, 5 parts of eucommia ulmoides extracts, 5 parts of rose oil, 3 parts, very heavy group of sandalwood oil
4 parts of extract solution, 3 parts of You Jiali extract solutions, 2 parts of siphon extract solution, 0.5 part of Ginger P.E, 2 parts of tea leaf oil, basil 1
Part, 2.5 parts of water, 2.5 parts of system stabilizers, 0.2 part of marine alga sodium metasilicate, 0.15 part of ethanol, in terms of weight fraction；
The eucommia ulmoides extracts extract from eucommia Bark male flower, and its specific preparation method is as follows：
(11) take and 24h in the sodium acetate aqueous solution that mass fraction is 25wt% is immersed at ripe eucommia Bark male flower, 35 DEG C, then
Take out, ventilation bakees drying at 45 DEG C, obtains bark of eucommia dried flower；
(12) obtained bark of eucommia dried flower in step (1) is smashed to pieces, and eucommia flower powder is immersed into ethyl acetate at 35 DEG C
12h in solvent, then repeatedly vacuum distillation recovered solvent after suction filtration 2 times, obtains one-level eucommia ulmoides extracts；
(13) 12h in ethanol will be immersed in one-level extract in step (2) at normal temperatures sealed environment, then repeatedly suction filtration
Vacuum distillation recovered solvent after 2 times, obtains two grades of eucommia ulmoides extracts；Two grades of eucommia ulmoides extracts obtain this hair with deionized water rinsing
Bright eucommia ulmoides extracts；
The specific preparation method of the siphon extract solution is as follows：
(21) take siphon rattan peel to be soaked in 24h in saturated aqueous common salt at 35 DEG C, then take out, divulge information and dry at 40 DEG C
Dry dry, obtain dry siphon rattan peel；
(22) the drying siphon rattan peel obtained in step (1) is crushed, and its powder is immersed in deionized water, big fire
Boil rear small fire and decoct 3h, be then filtrated to get siphon rattan peel one-level extract solution；
(23) rectifying will be carried out under the siphon rattan peel one-level extract solution reduced pressure 0.002MPa obtained in step (2),
The cut of 80~82 DEG C of boiling ranges is extracted, siphon extract solution is obtained；
The system stabilizers include following component：
Further, the thickener is or plain digested tankage.
The present invention also provides the preparation method of above-mentioned pain relieving ointment of releiving, it is characterised in that specific as follows：
(31) by peppermint leaf oil, citronella grass oil, blue gum leaf oil, rose oil, tea leaf oil, basil, methyl salicylate, very heavy group
It is uniformly mixed under extract solution and sandalwood oil room temperature condition, then adds You Jiali extract solutions, siphon extract solution and life
Ginger extract continues to stir to well mixed；
(32) above-mentioned system is warming up to 35 DEG C and adds algin, water and marine alga sodium metasilicate, continue to add after being stirred until homogeneous
Enter eucommia ulmoides extracts and ethanol, continue to stir 2h and system is down to room temperature in whipping process, rear addition glycerine and system are steady
Determine agent stirring 0.5h and obtain pain relieving ointment of releiving.
The cream provided in the present invention can be used for the treatment of painful swelling of joints, be the curative effect for further verifying this prescription to patient,
Treatment track record is carried out to 100 cases, patient is divided into gently by patient's average age 44~66 years old, average course of disease 4.5 years
Degree, moderate and severe, the normal walking of patients with mild is particularly overcast and rainy mild pain sensation；Moderate patient normally walks spy
It is not overcast and rainy to have obvious sensation of pain；Severe patient can not normally walk substantially.Treated using this prescription, specific side
Method is erasing, three times per day, half an hour is massaged after erasing, and for different degrees of patient, therapeutic effect is as shown in table 1, effective
Refer to after medication effect in 5 days significantly, the case that eliminates of pain；Effectively refer to that effect is notable, pain elimination in 20 days
In case, invalid finger 30 days substantially to no effect, the indelible case of pain；Recovery from illness refers in 5 days effect significantly and 180 days
The case not recurred inside.
Table 1 is using efficacy data of the medicine of the present invention to different painful swelling of joints degree patients
| Degree | Recovery from illness | It is effective | Effectively | It is invalid | It is total | It is efficient |
| Slightly | 18 | 30 | 8 | 2 | 58 | 96.6% |
| Moderate | 7 | 12 | 4 | 3 | 26 | 88.5% |
| Severe | 4 | 4 | 5 | 3 | 16 | 81.2% |
Further to verify the security of this prescription, kept track of while carrying out drug therapy control to another crowd of patient,
100 patients of same selection, patient's average age 44~66 years old, average course of disease 4.5 years, treatment group is controlled using this drug administration
Treat, control group uses general analgesic drug product drug treatment, is periodically administered and periodically carries out liver function test, through randomized controlled treatment knot
Fruit proves that the phenomenon normally, without transaminase jumped using treatment group's Liver function grade of this medicine, patient's states are steady；Using
Compare the patient of administration, occur the elevated phenomenon of transaminase in Liver function grade, and also have simultaneously some patientss with dizziness,
The phenomenon of vomiting, is thus proved, the security that this medicine is used.
Embodiment 2：One kind is releived pain relieving ointment, including following component：28 parts of glycerine, 8 parts of algin, 1 part of methyl salicylate, peppermint
20 parts of leaf oil, 7 parts of citronella grass oil, 8 parts of blue gum leaf oil, 20 parts of eucommia ulmoides extracts, 10 parts of rose oil, 10 parts of sandalwood oil is very heavy
Dial 10 parts of extract solution, 10 parts of You Jiali extract solutions, 8 parts of siphon extract solution, 1.5 parts of Ginger P.E, 5 parts of tea leaf oil, sweet basil
5 parts of oil, 18 parts of water, 5 parts of system stabilizers, plain 3.7 parts of digested tankage, 4.2 parts of ethanol, in terms of weight fraction；
The eucommia ulmoides extracts extract from eucommia Bark male flower, and its specific preparation method is as follows：
(11) take and 36h in the sodium acetate aqueous solution that mass fraction is 25wt% is immersed at ripe eucommia Bark male flower, 40 DEG C, then
Take out, ventilation bakees drying at 50 DEG C, obtains bark of eucommia dried flower；
(12) obtained bark of eucommia dried flower in step (1) is smashed to pieces, and eucommia flower powder is immersed into ethyl acetate at 45 DEG C
24h in solvent, then repeatedly vacuum distillation recovered solvent after suction filtration 4 times, obtains one-level eucommia ulmoides extracts；
(13) 24h in ethanol will be immersed in one-level extract in step (2) at normal temperatures sealed environment, then repeatedly suction filtration
Vacuum distillation recovered solvent after 4 times, obtains two grades of eucommia ulmoides extracts；Two grades of eucommia ulmoides extracts obtain this hair with deionized water rinsing
Bright eucommia ulmoides extracts；
The specific preparation method of the siphon extract solution is as follows：
(21) take siphon rattan peel to be soaked in 36h in saturated aqueous common salt at 45 DEG C, then take out, divulge information and dry at 55 DEG C
Dry dry, obtain dry siphon rattan peel；
(22) the drying siphon rattan peel obtained in step (1) is crushed, and its powder is immersed in deionized water, big fire
Boil rear small fire and decoct 6h, be then filtrated to get siphon rattan peel one-level extract solution；
(23) rectifying will be carried out under the siphon rattan peel one-level extract solution reduced pressure 0.003MPa obtained in step (2),
The cut of 83~85 DEG C of boiling ranges is extracted, siphon extract solution is obtained；
The system stabilizers include following component：
Further, the thickener is marine alga sodium metasilicate or plain digested tankage.
The present invention also provides the preparation method of above-mentioned pain relieving ointment of releiving, it is characterised in that specific as follows：
(31) by peppermint leaf oil, citronella grass oil, blue gum leaf oil, rose oil, tea leaf oil, basil, methyl salicylate, very heavy group
It is uniformly mixed under extract solution and sandalwood oil room temperature condition, then adds You Jiali extract solutions, siphon extract solution and life
Ginger extract continues to stir to well mixed；
(32) above-mentioned system is warming up to 35~45 DEG C and adds algin, water and plain digested tankage, continue to add after being stirred until homogeneous
Enter eucommia ulmoides extracts and ethanol, continue to stir 2~4h and system is down to room temperature in whipping process, it is rear to add glycerine and system
Stabilizer stirs 0.5~1h and obtains pain relieving ointment of releiving.
Medicine is applied to the treatment for the treatment of traumatic injury in the present embodiment, is the treatment for further verifying this prescription to patient
100 cases are carried out treatment track record by effect, and patient is divided into by patient's average age 15~70 years old, average course of disease 2.5 months
Slightly, moderate and severe, patients with mild pressing affected part have hypodynia sensation；Moderate patient, which does not press, has obvious pain
Feel；Severe patient pain sense is larger, influences normal life；Treated using this prescription, specific method is erasing, one day three
It is secondary, half an hour is massaged after erasing, for different degrees of patient, therapeutic effect is as shown in table 2, effective to refer to after medication in 5 days
The case that effect is notable, pain is eliminated；Effectively refer to effect in 20 days significantly, the case that eliminates of pain, invalid finger 30 days
Inside substantially to no effect, the indelible case of pain；Recovery from illness refers to the case that effect does not recur significantly and in 180 days in 5 days.
Table 2 is using efficacy data of the medicine of the present invention to different degrees of traumatic injury patient
| Degree | Recovery from illness | It is effective | Effectively | It is invalid | It is total | It is efficient |
| Slightly | 18 | 24 | 15 | 3 | 60 | 95.0% |
| Moderate | 3 | 15 | 3 | 2 | 23 | 91.3% |
| Severe | 2 | 10 | 5 | 3 | 17 | 82.3% |
Proved by upper table, using this drug therapy traumatic injury, preferable curative effect be respectively provided with for different degrees of patient,
And toxic side effect is substantially zero, used suitable for various crowds treatment.
Embodiment 3：One kind is releived pain relieving ointment, including following component：28 parts of glycerine, 6 parts of algin, 0.8 part of methyl salicylate is thin
15 parts of lotus leaf oil, 5 parts of citronella grass oil, 4 parts of blue gum leaf oil, 18 parts of eucommia ulmoides extracts, 8 parts of rose oil, 4 parts of sandalwood oil is very heavy
Dial 8 parts of extract solution, 8 parts of You Jiali extract solutions, 3.5 parts of siphon extract solution, 1 part of Ginger P.E, 2 parts of tea leaf oil, basil 2
Part, 5 parts of water, 3.95 parts of system stabilizers, 1 part of marine alga sodium metasilicate, 2 parts of ethanol, in terms of weight fraction；
The eucommia ulmoides extracts extract from eucommia Bark male flower, and its specific preparation method is as follows：
(11) take and 30h in the sodium acetate aqueous solution that mass fraction is 25wt% is immersed at ripe eucommia Bark male flower, 38 DEG C, then
Take out, ventilation bakees drying at 48 DEG C, obtains bark of eucommia dried flower；
(12) obtained bark of eucommia dried flower in step (1) is smashed to pieces, and eucommia flower powder is immersed into ethyl acetate at 40 DEG C
20h in solvent, then repeatedly vacuum distillation recovered solvent after suction filtration 3 times, obtains one-level eucommia ulmoides extracts；
(13) 20h in ethanol will be immersed in one-level extract in step (2) at normal temperatures sealed environment, then repeatedly suction filtration
Vacuum distillation recovered solvent after 3 times, obtains two grades of eucommia ulmoides extracts；Two grades of eucommia ulmoides extracts obtain this hair with deionized water rinsing
Bright eucommia ulmoides extracts；
The specific preparation method of the siphon extract solution is as follows：
(21) take siphon rattan peel to be soaked in 30h in saturated aqueous common salt at 40 DEG C, then take out, divulge information and dry at 50 DEG C
Dry dry, obtain dry siphon rattan peel；
(22) the drying siphon rattan peel obtained in step (1) is crushed, and its powder is immersed in deionized water, big fire
Boil rear small fire and decoct 4h, be then filtrated to get siphon rattan peel one-level extract solution；
(23) rectifying will be carried out under the siphon rattan peel one-level extract solution reduced pressure 0.0025MPa obtained in step (2),
The cut of 82~84 DEG C of boiling ranges is extracted, siphon extract solution is obtained；
The system stabilizers include following component：
The preparation method of above-mentioned pain relieving ointment of releiving, it is specific as follows：
(31) by peppermint leaf oil, citronella grass oil, blue gum leaf oil, rose oil, tea leaf oil, basil, methyl salicylate, very heavy group
It is uniformly mixed under extract solution and sandalwood oil room temperature condition, then adds You Jiali extract solutions, siphon extract solution and life
Ginger extract continues to stir to well mixed；
(32) above-mentioned system is warming up to 40 DEG C and adds algin, water and thickener, continue to add Du after being stirred until homogeneous
Secondary extract and ethanol, continue to stir 3h and system are down to room temperature in whipping process, rear to add glycerine and system stabilizers
Stirring 1h obtains pain relieving ointment of releiving.
The condensation provided in the present invention can be used for treatment hemorrhoid, be the curative effect for further verifying this prescription to patient, to 100
Name case carry out treatment track record, patient's average age 25~50 years old, average course of disease 2.5 years, by patient be divided into slightly, moderate
And severe, normally walking has mild pain sensation to patients with mild；Normally walking has obvious sensation of pain to moderate patient；Severe is suffered from
Person can not normally walk substantially.Treated using this prescription, specific method is erasing, three times per day, half is massaged after erasing small
When, for different degrees of patient, therapeutic effect as shown in table 3, it is effective refer to after medication in 5 days effect significantly, pain disappears
The case removed；Effectively refer to effect in 20 days significantly, the case that eliminates of pain, in invalid finger 30 days substantially to no effect, pain
Feel indelible case；Recovery from illness refers to the case that effect does not recur significantly and in 180 days in 5 days.
Table 3 is using efficacy data of the medicine of the present invention to different degrees of hemorrhoid patients
| Degree | Recovery from illness | It is effective | Effectively | It is invalid | It is total | It is efficient |
| Slightly | 15 | 26 | 9 | 6 | 56 | 89.3% |
| Moderate | 6 | 9 | 5 | 4 | 24 | 83.3% |
| Severe | 4 | 6 | 6 | 4 | 20 | 80.0% |
Further to verify the security of this prescription, kept track of while carrying out drug therapy control to another crowd of patient,
100 patients of same selection, patient's average age 25~50 years old, average course of disease 2.5 years, treatment group is controlled using this drug administration
Treat, control group uses general hemorrhoid treating class Western medicine drug treatment, be periodically administered and periodically carry out liver function test, through control
Treatment results prove that the phenomenon normally, without transaminase jumped using treatment group's Liver function grade of this medicine, patient's states are put down
Surely；Using the patient of control administration, occur the elevated phenomenon of transaminase in Liver function grade, and also have some patientss companion simultaneously
There are dizziness, the phenomenon of vomiting, thus prove, the security that this medicine is used.
Proved by upper table, using this drug therapy hemorrhoid, preferable curative effect, and poison are respectively provided with for different degrees of patient
Side effect is substantially zero, and is used suitable for various crowds treatment.
As described above, although the present invention has been represented and described with reference to specific preferred embodiment, it must not be explained
For to the limitation of itself of the invention., can be right under the premise of the spirit and scope of the present invention that appended claims are defined are not departed from
Various changes can be made in the form and details for it.
Claims (6)
- The pain relieving ointment 1. one kind is releived, it is characterised in that including following component：10~30 parts of glycerine, 2~8 parts of algin, methyl salicylate 0.5~1 part, 10~20 parts of peppermint leaf oil, 5~7 parts of citronella grass oil, 4~8 parts of blue gum leaf oil, 5~20 parts of eucommia ulmoides extracts, rose Rare 5~10 parts of caul-fat, 3~10 parts of sandalwood oil, very heavy group of 4~10 parts of extract solution, 3~10 parts of You Jiali extract solutions, siphon is carried Take 2~8 parts of liquid, 0.5~1.5 part of Ginger P.E, 2~5 parts of tea leaf oil, 1~5 part of basil, 1~20 part of water, stable system 2~5 parts of agent, 0.05~3 part of thickener, 0.1~5 part of ethanol, in terms of weight fraction；The eucommia ulmoides extracts extract from eucommia Bark male flower, and its specific preparation method is as follows：(11) take and 24~36h in the sodium acetate aqueous solution that mass fraction is 25wt% immersed at ripe eucommia Bark male flower, 35~40 DEG C, Then take out, ventilation bakees drying at 45~50 DEG C, obtains bark of eucommia dried flower；(12) obtained bark of eucommia dried flower in step (1) is smashed to pieces, and eucommia flower powder is immersed into ethyl acetate at 35~45 DEG C 12~24h in solvent, then repeatedly vacuum distillation recovered solvent after suction filtration 2~4 times, obtains one-level eucommia ulmoides extracts；(13) 12~24h in ethanol will be immersed in one-level extract in step (2) at normal temperatures sealed environment, then repeatedly suction filtration Vacuum distillation recovered solvent after 2~4 times, obtains two grades of eucommia ulmoides extracts；Two grades of eucommia ulmoides extracts are obtained with deionized water rinsing The eucommia ulmoides extracts of the present invention；The specific preparation method of the siphon extract solution is as follows：(21) take siphon rattan peel to be soaked in 24~36h in saturated aqueous common salt at 35~45 DEG C, then take out, at 40~55 DEG C Lower ventilation bakees drying, obtains dry siphon rattan peel；(22) the drying siphon rattan peel obtained in step (1) is crushed, and its powder is immersed in deionized water, be boiled by fire Small fire decocts 3~6h afterwards, is then filtrated to get siphon rattan peel one-level extract solution；(23) it will be carried out under the siphon rattan peel one-level extract solution reduced pressure 0.002MPa~0.003MPa obtained in step (2) Rectifying, extracts the cut of 80~85 DEG C of boiling ranges, obtains siphon extract solution；The system stabilizers include following component：In terms of weight fraction.
- 2. pain relieving ointment according to claim 1 of releiving, it is characterised in that：The thickener is marine alga sodium metasilicate or plain meat Powder.
- 3. the preparation method for pain relieving ointment of being releived described in a kind of claim 1, it is characterised in that specific as follows：(31) by peppermint leaf oil, citronella grass oil, blue gum leaf oil, rose oil, tea leaf oil, basil, methyl salicylate, very heavy group of extraction It is uniformly mixed under liquid and sandalwood oil room temperature condition, then adds You Jiali extract solutions, siphon extract solution and ginger and carry Thing is taken to continue to stir to well mixed；(32) above-mentioned system is warming up to 35~45 DEG C and adds algin, water and thickener, continue to add Du after being stirred until homogeneous Secondary extract and ethanol, continue to stir 2~4h and system are down to room temperature in whipping process, rear to add glycerine and stable system Agent stirs 0.5~1h and obtains pain relieving ointment of releiving.
- 4. application of the pain relieving ointment in treatment traumatic injury, painful swelling of joints medicine of being releived described in claim 1.
- 5. application of the pain relieving ointment in medicine for treaching hemorrhoie of being releived described in claim 1.
- 6. application according to claim 5, it is characterised in that the pain relieving ointment of releiving includes following component：28 parts of glycerine, 6 parts of algin, 0.8 part of methyl salicylate, 15 parts of peppermint leaf oil, 5 parts of citronella grass oil, 4 parts of blue gum leaf oil, 18 parts of eucommia ulmoides extracts, rose Rare 8 parts of caul-fat, 4 parts of sandalwood oil, very heavy group of 8 parts of extract solution, 8 parts of You Jiali extract solutions, 3.5 parts of siphon extract solution, ginger is carried Take 1 part of thing, 2 parts of tea leaf oil, 2 parts of basil, 5 parts of water, 2.5 parts of system stabilizers, 1 part of thickener, 2 parts of ethanol, with weight point Number meter.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107926249A (en) * | 2017-11-27 | 2018-04-20 | 桂林斯泰硕农农业科技有限公司 | Fertilizing method for enhancing anticancer effect of Bufna rhizome |
| CN108485491A (en) * | 2018-04-08 | 2018-09-04 | 上海睿沁环保科技有限公司 | A kind of solid wood furniture surface peculiar smell removes care agent |
| CN108485488A (en) * | 2018-04-08 | 2018-09-04 | 上海睿沁环保科技有限公司 | A kind of degradable formaldehyde high-efficiency scavenging agent |
| CN108524779A (en) * | 2018-06-25 | 2018-09-14 | 安徽德睿轩科技服务有限公司 | A kind of ointment that treating anorectal disease and application |
| CN108607357A (en) * | 2018-04-08 | 2018-10-02 | 上海睿沁环保科技有限公司 | A kind of efficiently automobile-used odor scavenging agent |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106215157A (en) * | 2016-08-29 | 2016-12-14 | 张东旭 | A kind of auxiliary moxibustion Chinese medicine oil and preparation method thereof |
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2017
- 2017-04-14 CN CN201710244151.5A patent/CN107096008A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106215157A (en) * | 2016-08-29 | 2016-12-14 | 张东旭 | A kind of auxiliary moxibustion Chinese medicine oil and preparation method thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107926249A (en) * | 2017-11-27 | 2018-04-20 | 桂林斯泰硕农农业科技有限公司 | Fertilizing method for enhancing anticancer effect of Bufna rhizome |
| CN108485491A (en) * | 2018-04-08 | 2018-09-04 | 上海睿沁环保科技有限公司 | A kind of solid wood furniture surface peculiar smell removes care agent |
| CN108485488A (en) * | 2018-04-08 | 2018-09-04 | 上海睿沁环保科技有限公司 | A kind of degradable formaldehyde high-efficiency scavenging agent |
| CN108607357A (en) * | 2018-04-08 | 2018-10-02 | 上海睿沁环保科技有限公司 | A kind of efficiently automobile-used odor scavenging agent |
| CN108524779A (en) * | 2018-06-25 | 2018-09-14 | 安徽德睿轩科技服务有限公司 | A kind of ointment that treating anorectal disease and application |
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Application publication date: 20170829 |