CN107050373A - A kind of medicament and preparation method for being used to treat the proliferation of mammary gland - Google Patents

A kind of medicament and preparation method for being used to treat the proliferation of mammary gland Download PDF

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CN107050373A
CN107050373A CN201611165942.0A CN201611165942A CN107050373A CN 107050373 A CN107050373 A CN 107050373A CN 201611165942 A CN201611165942 A CN 201611165942A CN 107050373 A CN107050373 A CN 107050373A
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parts
proliferation
treat
medicament
mammary gland
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张爱琴
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/89—Cyperaceae (Sedge family)
    • A61K36/8905—Cyperus (flatsedge)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The present invention relates to a kind of medicament for being used to treat the proliferation of mammary gland, it is characterised in that is made up of the bulk drug of following parts by weight meter：15 parts of radix bupleuri, 15 parts of Radix Angelicae Sinensis, 30 parts of raw oyster, 15 parts of the rhizome of nutgrass flatsedge, 15 parts of tangerine core, 12 parts of Fructus meliae toosendan, 40 parts of full Snakegourd Fruit, 15 parts of prepared RHIZOMA PINELLIZE without adju-vant, 15 parts of curcuma zedoary, 20 parts of marine alga, 20 parts of the seed of cowherb, 20 parts of spina gleditsiae, 20 parts of stir-baked RADIX PAEONIAE ALBA, raw 15 parts of corydalis tuber, 20 parts of reticulate millettia, 20 parts of astragalus root, 15 parts of fuling peel.The present invention also provides the preparation method of the medicament.Play the role of liver soothing and depression relief, regulating qi-flowing for relieving pain, activate blood circulation and disperse blood clots, softening and resolving hard mass, reach elimination lump, pain of alleviation, treat the proliferation of mammary gland purpose.

Description

A kind of medicament and preparation method for being used to treat the proliferation of mammary gland
Technical field
The present invention relates to the treatment technology field of cyclomastopathy, a kind of medicine for being used to treat the proliferation of mammary gland is specifically related to Agent and preparation method.
Background technology
The proliferation of mammary gland is the most common breast disease of women, and its incidence of disease accounts for the first place of mammary gland disease.The disease in the last few years The incidence of disease also shows the feature of becoming younger in the trend risen year by year, and age.Cyclomastopathy is normal breast leaflet physiology Property hyperplasia and subinvolution, mammary gland normal configuration get muddled, and belong to pathological proliferation, and it is not only noninflammatory but also the one of non-tumour Class disease.
The content of the invention
The technical problems to be solved by the invention be to provide it is a kind of be used to treat the medicament of the proliferation of mammary gland, have liver soothing and depression relief, Regulating qi-flowing for relieving pain, activate blood circulation and disperse blood clots, the effect of softening and resolving hard mass, reach elimination lump, pain of alleviation, treat the proliferation of mammary gland purpose.This Invention also provides the preparation method of the medicament.
In order to solve the above technical problems, the present invention provides following technical scheme：A kind of medicament for being used to treat the proliferation of mammary gland, It is made up of the bulk drug of following parts by weight meter：15 parts of radix bupleuri, 15 parts of Radix Angelicae Sinensis, 30 parts of raw oyster, 15 parts of the rhizome of nutgrass flatsedge, 15 parts of tangerine core, 12 parts of Fructus meliae toosendan, 40 parts of full Snakegourd Fruit, 15 parts of prepared RHIZOMA PINELLIZE without adju-vant, 15 parts of curcuma zedoary, 20 parts of marine alga, 20 parts of the seed of cowherb, 20 parts of spina gleditsiae, stir-fry are white 20 parts of Chinese herbaceous peony, raw 15 parts of corydalis tuber, 20 parts of reticulate millettia, 20 parts of astragalus root, 15 parts of fuling peel.
A kind of medicament preparation method for being used to treat the proliferation of mammary gland, every dose of medicine is by the bulk drug of following weight under Step is stated to be prepared from：
(1) raw oyster 30g is taken, 30min, then fried 30min are first soaked in 200ml water；
(2) by radix bupleuri 15g, Radix Angelicae Sinensis 15g, rhizome of nutgrass flatsedge 15g, tangerine core 15g, Fructus meliae toosendan 12g, full Snakegourd Fruit 40g, prepared RHIZOMA PINELLIZE without adju-vant 15g, Curcuma zedoary 15g, marine alga 20g, seed of cowherb 20g, spina gleditsiae 20g, stir-baked RADIX PAEONIAE ALBA 20g, raw corydalis tuber 15g, reticulate millettia 20g, astragalus root 20g, Fuling peel 15g, adds in raw oyster that fried 40min, to 250-300ml, is cleared out again together after soaking 30min in 500ml water First time concoction；Add clear water 500ml and continue fried 40min to 250ml-300ml, clear out second of concoction；
(3) the first time concoction of step (2) and second of concoction are mixed.
The present invention has an advantageous effect in that compared with prior art：The medicament that the present invention is provided is according to above-mentioned preparation side Method, which is boiled, to be formed, one portion per day, point 2-3 one after each meal, is avoided pungent stimulation stodge, is given up alcohol.The medicament has liver of relaxing Xie Yu, regulating qi-flowing for relieving pain, activate blood circulation and disperse blood clots, the effect of softening and resolving hard mass, can reach elimination lump, pain of alleviation, treat the proliferation of mammary gland Effect.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
A kind of medicament for being used to treat the proliferation of mammary gland, is made up of the bulk drug of following parts by weight meter：Radix bupleuri 15g, raw oyster 30g, Radix Angelicae Sinensis 15g, rhizome of nutgrass flatsedge 15g, tangerine core 15g, Fructus meliae toosendan 12g, full Snakegourd Fruit 40g, prepared RHIZOMA PINELLIZE without adju-vant 15g, curcuma zedoary 15g, marine alga 20g, Seed of cowherb 20g, spina gleditsiae 20g, stir-baked RADIX PAEONIAE ALBA 20g, raw corydalis tuber 15g, reticulate millettia 20g, astragalus root 20g, fuling peel 15g.
The preparation method of above-mentioned medicament, every dose of medicine is prepared from as steps described below by the bulk drug of following weight：
(1) raw oyster 30g is taken, 30min, then fried 30min are first soaked in 200ml water；
(2) by radix bupleuri 15g, Radix Angelicae Sinensis 15g, rhizome of nutgrass flatsedge 15g, tangerine core 15g, Fructus meliae toosendan 12g, full Snakegourd Fruit 40g, prepared RHIZOMA PINELLIZE without adju-vant 15g, Curcuma zedoary 15g, marine alga 20g, seed of cowherb 20g, spina gleditsiae 20g, stir-baked RADIX PAEONIAE ALBA 20g, raw corydalis tuber 15g, reticulate millettia 20g, astragalus root 20g, Fuling peel 15g, adds in raw oyster that fried 40min, to 250-300ml, is cleared out again together after soaking 30min in 500ml water First time concoction；Add clear water 500ml and continue fried 40min to 250ml-300ml, clear out second of concoction；
(3) the first time concoction of step (2) and second of concoction are mixed.
Criterion of therapeutical effect：Lump is wholly absent after treatment, breast also without pain, and items check normal, do not recur within more than 1 year Person is recovery from illness；Lump is wholly absent after treatment, and breast pain takes a turn for the better, and items check normal, does not recur to take a turn for the better in 1 year；Treatment Mass reduction or quantity are reduced afterwards, but not as good as 1/2, feel that breast pain and tenderness have mitigated, and items check that normal is aobvious Effect；The unchanged lump of the state of an illness is substantially unchanged after treatment, and pain is also without obvious mitigation, then to be invalid.
Patient is according to one portion per day, point 2-3 one after each meal medicament of the invention, and it is a course for the treatment of to take 3 weeks, according to disease The recovery situation of people can treat the 1-2 course for the treatment of.During taking, avoid pungent stimulation stodge, give up alcohol.By there is a course for the treatment of Observation, it is found that all patients are treated effectively, cure rate reaches more than 65%, and it was observed that bright during whole treatment Aobvious adverse reaction.Follow-up is carried out to patient weekly after a course for the treatment of is treated, continues half a year, the mark of recurrence is not found As.

Claims (2)

1. a kind of medicament for being used to treat the proliferation of mammary gland, it is characterised in that be made up of the bulk drug of following parts by weight meter：Radix bupleuri 15 Part, 15 parts of Radix Angelicae Sinensis, 30 parts of raw oyster, 15 parts of the rhizome of nutgrass flatsedge, 15 parts of tangerine core, 12 parts of Fructus meliae toosendan, 40 parts of full Snakegourd Fruit, 15 parts of prepared RHIZOMA PINELLIZE without adju-vant, 15 parts of curcuma zedoary, 20 parts of marine alga, 20 parts of the seed of cowherb, 20 parts of spina gleditsiae, 20 parts of stir-baked RADIX PAEONIAE ALBA, raw 15 parts of corydalis tuber, 20 parts of reticulate millettia, process Huang 20 parts of stilbene, 15 parts of fuling peel.
2. a kind of be used to treat the medicament preparation method of the proliferation of mammary gland, it is characterised in that every dose of medicine by following weight original Material medicine is prepared from as steps described below：
(1) raw oyster 30g is taken, 30min, then fried 30min are first soaked in 200ml water；
(2) by radix bupleuri 15g, Radix Angelicae Sinensis 15g, rhizome of nutgrass flatsedge 15g, tangerine core 15g, Fructus meliae toosendan 12g, full Snakegourd Fruit 40g, prepared RHIZOMA PINELLIZE without adju-vant 15g, curcuma zedoary 15g, marine alga 20g, seed of cowherb 20g, spina gleditsiae 20g, stir-baked RADIX PAEONIAE ALBA 20g, raw corydalis tuber 15g, reticulate millettia 20g, astragalus root 20g, Poria cocos Skin 15g, adds in raw oyster that fried 40min, to 250-300ml, clears out first again together after soaking 30min in 500ml water Secondary concoction；Add clear water 500ml and continue fried 40min to 250ml-300ml, clear out second of concoction；
(3) the first time concoction of step (2) and second of concoction are mixed.
CN201611165942.0A 2016-12-08 2016-12-08 A kind of medicament and preparation method for being used to treat the proliferation of mammary gland Pending CN107050373A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113144148A (en) * 2021-05-20 2021-07-23 漳州卫生职业学院 Oral and external traditional Chinese medicine for treating liver depression, phlegm dampness and blood stasis type hyperplasia of mammary glands and preparation method thereof

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Application publication date: 20170818