CN107029072A - A kind of Hibisci Paste with antiinflammatory action - Google Patents
A kind of Hibisci Paste with antiinflammatory action Download PDFInfo
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- CN107029072A CN107029072A CN201710464906.2A CN201710464906A CN107029072A CN 107029072 A CN107029072 A CN 107029072A CN 201710464906 A CN201710464906 A CN 201710464906A CN 107029072 A CN107029072 A CN 107029072A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8884—Arisaema, e.g. Jack in the pulpit
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
A kind of Hibisci Paste with antiinflammatory action of the present invention, belongs to technical field of traditional Chinese medicines；It is prepared from by the raw material of following weight：10 20 parts of cotton rose, 10 20 parts of gamboge, 10 15 parts of arisacma consanguineum schott, 6 12 parts of borneol, 5 12 parts of peppermint oil, 120 200 parts of vaseline；Hibisci Paste compatibility science of the present invention and rigorous, formula is unique, manufacture craft is simple and convenient easy, has given full play to the advantage of Chinese medicine external " many target effects ", the curative effect for making it play uniqueness to multi-infection and non-infection illness；It can be applied to bacterial inflammation and non-bacteria inflammation；Acute inflammation and chronic inflammation are combined；The symptom such as acute toxicity and chronic toxicity, superficial infection and deep infection, local toxicity and general toxic reaction.
Description
Technical field
A kind of Hibisci Paste with antiinflammatory action of the present invention, belongs to technical field of traditional Chinese medicines.
Background technology
Sore refers to body surface illness caused by after various pathogenic factor invasion and attack human bodies.《Surgery opens profound》Say：" husband sore person,
It is total name of sore.Sore person hinders, and muscle is addled, and pain wound is rotten to be formed, therefore named to say sore.One of sore word, institute Bao Zheguang.Have
Carbuncle, subcutaneous ulcer, malignant boil, furuncle, scrofula, scabies, tinea, infantile malnutrition due to digestive disturbances or intestinalparasites, poison, acne, rash decile.
External treatment of traditional Chinese medicine is thought：The yang syndrome sore at initial stage, is expensive with " disappearing ", can select encircling drugs JINHUANG SAN, YULU SAN
Etc. the clearing heat and detoxicating, promoting flow of qi and blood circulation, swelling and pain relieving, crowded around with binding round collection, collect sore；The moon card sore, still with " disappearing " to be expensive, therapy with
Warming and activating meridian, based on cold dispelling resolving sputum；Half cloudy half light therapy is eliminating stasis to subdue swelling, the promoting flow of qi and blood circulation.And diabetic foot ulcer is diabetes
One of chronic complicating diseases, be also important a kind of Clinical types in traditional Chinese medical science plant sore, traditional Chinese medicine is controlled diabetic foot ulcer
Treat and preventing and treating aspect has larger advantage, especially external treatment with Chinese medicine to promoting local woanded surface healing aspect to serve very big work
With largely reducing amputation rate.
At present, western medical treatment method is taken for sore, diabetic foot ulcer treatment, therapeutic effect is limited, again can not root
Control the chronic progressive disease.Chinese medicine is relaxed due to effect, and few side effects can effectively be treated from root, therefore is badly in need of
One kind mitigates patient's slight illness, plays antibacterial, elimination active chronic inflammation, the traditional Chinese medicinal ointment of dispersing swelling and dissipating binds.
The content of the invention
The present invention is not ideal for treatment sore, diabetic foot ulcer effect to solve existing medicine, it is impossible to from root
The problem of upper effectively treatment, there is provided a kind of Hibisci Paste with antiinflammatory action.
In order to solve the above technical problems, the technical solution adopted in the present invention is：A kind of Hibisci Paste with anti-inflammatory, by
The raw material of following weight is prepared from：10-20 parts of cotton rose, 10-20 parts of gamboge, 10-15 parts of arisacma consanguineum schott, borneol
6-12 parts, 5-12 parts of peppermint oil, 120-200 parts of vaseline.
A kind of described Hibisci Paste with antiinflammatory action, is prepared from by the raw material of following weight：Cotton rose
15-18 parts, 12-17 parts of gamboge, 12-15 parts of arisacma consanguineum schott, 8-10 parts of borneol, 7-9 parts of peppermint oil, 120-160 parts of vaseline.
Described a kind of Hibisci Paste with antiinflammatory action, it is characterised in that prepared by the raw material of following weight
Form：18 parts of cotton rose, 17 parts of gamboge, 15 parts of arisacma consanguineum schott, 9 parts of borneol, 8 parts of peppermint oil, 154 parts of vaseline.
A kind of preparation method of the Hibisci Paste with antiinflammatory action, comprises the following steps：By the wood of above-mentioned weight
Lotus, gamboge, arisacma consanguineum schott and borneol and grinding are mixed into powder, then with weight peppermint oil, be well mixed after again with weight
The vaseline modulation paste of part proportioning.
The Hibisci Paste is applied to multi-infection and non-infection illness.
Each traditional Chinese medicine ingredients pharmaceutical characteristic is as follows in the present invention：
Cotton rose：《Compendium of Materia Medica》：" cotton rose Qingfei Liangxue, radiating removing toxic substances.Control all size swollen ulcer drug malignant sores, detumescence row
Pus and pain." cotton rose antiinflammatory action zoopery and clinical observation, be respectively provided with antiinflammatory action.
Gamboge：《The lifesaving sea of bitterness》：" control all nameless sores or boils, and counterpart carbuncle on the back：Drop flower liquor, mill gamboge is applied, not stopped deposited
It." gamboge has certain bacteriostasis.
Arisacma consanguineum schott：《Chinese Pharmacopoeia》：" Southern Star is eliminating dampness and eliminating phlegm, mass dissipating and swelling eliminating, life controlling outward carbuncle swells, snake bite and insect sting.It is clinical and
Animal experiment observes that arisacma consanguineum schott has antibacterial and bacteriostasis
Borneol：Ancient literature《Compendium of Materia Medica》、《Mingyi Bielu》Recognize that the locally and systemically anti-inflammatory of borneol is answered Deng.It is modern
Research is, it was also found that borneol has good Transdermal absorption effect, and it has antiinflammatory action.
Peppermint oil：《Chinese medicine voluminous dictionary》：" peppermint oil is pungent, cool, nontoxic.Aromatic drug, remedium corrigens and carminative.It can use
Refrigerant sense is produced in skin or mucous membrane to mitigate to be not suitable for, main pain.
Compatibility parsing of the present invention is as follows：
Monarch drug in a prescription：It is the medicine for playing primary treatment for main disease or main symptom.It is indispensable medicine first of in its efficacy of a drug side of residence
Thing.The present invention is using cotton rose as " monarch ", clearing heat and detoxicating, detumescence and apocenosis, cooling blood and hemostasis；Carbuncle swells boil is controlled in external application, and mastitis is drenched
Fawn on inflammation, parotitis, burn and scald, venomous snake bite, traumatic injury.
Ministerial drug：One is the medicine for aiding in monarch drug in a prescription to strengthen the main disease for the treatment of or main symptom；Two be to play treatment for simultaneous disease or accompanying symptoms to make
Medicine.Its efficacy of a drug is less than monarch drug in a prescription.The present invention is with gamboge, and arisacma consanguineum schott is " minister ", and gamboge is swollen, detoxification, hemostasis, desinsection.Control
Swollen ulcer drug, stubborn dermatitis malignant sore, bleeding due to trauma, noma decayed tooth, burn；Arisacma consanguineum schott, eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, dissipating bind disappears
It is swollen, life controlling outward carbuncle swells, snake bite and insect sting.
Adjutant：Supplementary drug, assists monarch, ministerial drug to strengthen therapeutic action, or directly treat minor symptom.The present invention is with ice
Piece, peppermint oil " assisting a ruler in governing a country ", can play promotion monarch, ministerial drug（Cotton rose, gamboge, arisacma consanguineum schott）Transdermal absorption, can strengthen anti-inflammatory again
And analgesic activity.
Compared with prior art the invention has the advantages that.
Hibisci Paste compatibility science of the present invention and rigorous, formula is unique, manufacture craft is simple and convenient easy, in having given full play to
The advantage of medicine external application " many target effects ", the curative effect for making it play uniqueness to multi-infection and non-infection illness.Infectious diseases is such as：
Furuncle, carbuncle（Doctor trained in Western medicine superficial abscess）, carbuncle（Doctor trained in Western medicine carbuncle）, acute appendicitis（Doctor trained in Western medicine appendiceal abscess）, erysipelas.Non-infectious inflammation disease
Such as：Goitre carbuncle（Subacute thyroiditis）, urarthritis, superficial thrombophlebitis
Hibisci Paste of the present invention can be applied to bacterial inflammation and non-bacteria inflammation；Acute inflammation and chronic inflammation are combined；It is acute
The symptom such as toxicity and chronic toxicity, superficial infection and deep infection, local toxicity and general toxic reaction.
Embodiment
Below in conjunction with specific embodiment, the invention will be further described.
Each component pharmaceutical research of the present invention is as follows：
Cotton rose：Animal experiment shows, cotton rose is to mouse knoting oil otitis disease, to Rat Carrageenan colloidality toes swelling, right
The Acute and chronic inflammations such as mouse granuloma induced by implantation of cotton pellets hyperplasia have inhibitory action；Meanwhile, also there is suppression to bacillus and coccus.
Gamboge：Bacteriostatic test shows that gamboge has inhibitory action to gram-positive cocci, while to acute and chronic inflammation
Reaction has obvious inhibiting effect.
Arisacma consanguineum schott：Mainly apply the pharmacotoxicological effect of its mass dissipating and swelling eliminating.
Borneol：One is that its good promotion is acted on through skin and mucosal absorption；Two be that the antibacterial and anti-inflammatory of itself is made
With.Pharmaceutical research shows that the former is acted on more than the latter for it.
Peppermint oil：As the pharmacotoxicological effect of borneol, the pharmacological action of peppermint oil be also chiefly to facilitate through skin and
Mucosal absorption is acted on and its antibacterial, anti-inflammatory, analgesic activity.
Embodiment 1
A kind of Hibisci Paste with anti-inflammatory, is prepared from by the raw material of following weight：10 parts of cotton rose, gamboge 20
Part, 10 parts of arisacma consanguineum schott, 12 parts of borneol, 5 parts of peppermint oil, 200 parts of vaseline.
A kind of preparation method of the Hibisci Paste with antiinflammatory action, comprises the following steps：By the wood of above-mentioned weight
Lotus, gamboge, arisacma consanguineum schott and borneol and grinding are mixed into powder, then with weight peppermint oil, be well mixed after again with weight
The vaseline modulation paste of part proportioning.
Embodiment 2
A kind of Hibisci Paste with anti-inflammatory, is prepared from by the raw material of following weight：20 parts of cotton rose, gamboge 10
Part, 15 parts of arisacma consanguineum schott, 6 parts of borneol, 12 parts of peppermint oil, 120 parts of vaseline.
A kind of preparation method of the Hibisci Paste with antiinflammatory action, comprises the following steps：By the wood of above-mentioned weight
Lotus, gamboge, arisacma consanguineum schott and borneol and grinding are mixed into powder, then with weight peppermint oil, be well mixed after again with weight
The vaseline modulation paste of part proportioning.
Embodiment 3
A kind of Hibisci Paste with antiinflammatory action, is prepared from by the raw material of following weight：15 parts of cotton rose, gamboge
17 parts, 12 parts of arisacma consanguineum schott, 10 parts of borneol, 7 parts of peppermint oil, 160 parts of vaseline.
A kind of preparation method of the Hibisci Paste with antiinflammatory action, comprises the following steps：By the wood of above-mentioned weight
Lotus, gamboge, arisacma consanguineum schott and borneol and grinding are mixed into powder, then with weight peppermint oil, be well mixed after again with weight
The vaseline modulation paste of part proportioning.
Embodiment 4
A kind of Hibisci Paste with antiinflammatory action, is prepared from by the raw material of following weight：18 parts of cotton rose, gamboge
12 parts, 15 parts of arisacma consanguineum schott, 8 parts of borneol, 9 parts of peppermint oil, 120 parts of vaseline.
A kind of preparation method of the Hibisci Paste with antiinflammatory action, comprises the following steps：By the wood of above-mentioned weight
Lotus, gamboge, arisacma consanguineum schott and borneol and grinding are mixed into powder, then with weight peppermint oil, be well mixed after again with weight
The vaseline modulation paste of part proportioning.
Embodiment 5
A kind of Hibisci Paste with antiinflammatory action, it is characterised in that be prepared from by the raw material of following weight：Cotton rose
18 parts, 17 parts of gamboge, 15 parts of arisacma consanguineum schott, 9 parts of borneol, 8 parts of peppermint oil, 154 parts of vaseline.
A kind of preparation method of the Hibisci Paste with antiinflammatory action, comprises the following steps：By the wood of above-mentioned weight
Lotus, gamboge, arisacma consanguineum schott and borneol and grinding are mixed into powder, then with weight peppermint oil, be well mixed after again with weight
The vaseline modulation paste of part proportioning.
The application method of Hibisci Paste of the present invention is：Affected part is cleaned up, takes the ointment of suitable size to be applied to affected part, one
Day once, 7 days courses for the treatment of
The using effect of the present invention clinically：
General information selects 100 Inpatients and is the sugared pedopathy patient of blood stasis train of thought type, is randomly divided into two groups.Control
Treatment group 50；The oldest 68 years old, minimum 37 years old, average (45.0 ± 10.2) year；The course of disease is most long 18 years, most short
2 years, average (7.0 ± 2.6) year.Control group 50；It is the oldest 66 years old, minimum 38 years old, average (44.2 ±
10.2) year；The course of disease is most long 16 years, most short 3 years.Two groups of general information comparing differences are not statistically significant (P ＞ 0.05)
, with comparativity.
Treatment group：The Hibisci Paste for giving the embodiment of the present invention 5 to prepare smears affected part daily 1 time.
Control group：Vaseline is given to smear affected part daily 1 time.
The course for the treatment of：Two groups are treated 4 weeks.
Efficacy evaluation：A situation arises for observation wound healing situation and adverse reaction after treatment.Clinical cure is local swelling
Disappear, skin color recovers normal, and ulcer surface heals completely；Effective is that local swelling and skin color improve, and ulcer surface reduces
More than 70%；Effectively it is that local swelling and skin color improve, ulcer surface reduces more than 30%；Invalid is not reach effective finger
Mark.Total effective rate is cure rate, obvious effective rate and efficient sum.
Treatment results：Treatment group cures 40, and effective 3, effective 6, invalid 1, cure rate is 80%,
Total effective rate is 98%, healing time 10~24 days.Control group cures 0, effective 0, effective 0；Invalid 50
Example, cure rate is 0%, and total effective rate is 0%, and two groups of cure rates, total effective rates compare, and difference has significant (P<
0.01)。
Typical case：Zhao, female, 22 years old.Readme：Psoas is caused to be pulled in physical education, second day injury redness,
Become big, handicapped, the pain increased, using the Hibisci Paste prepared by the embodiment of the present invention 1, after a course for the treatment of, pain mitigates,
Redness disappears.It is continuing with swelling position after two courses for the treatment of to be wholly absent, fully recovers.
Zhang, man, 40 years old, suffers from erysipelas（Lymphatic meshwork is scorching）, position is red and swollen, becomes big, handicapped, pain uses this hair
After Hibisci Paste prepared by bright embodiment 2, two courses for the treatment of, pain mitigates, and redness disappears.It is continuing with after two courses for the treatment of red and swollen
Disappear.
Certain is thanked, female, 30 years old, superficial soft tissue infection at shoulder, position was red and swollen, has the small purulence head of yellow-white, uses the present invention
After Hibisci Paste prepared by embodiment 5, a course for the treatment of, pain mitigates, and redness disappears.Purulent core after two courses for the treatment of is continuing with to take off
Fall, discharge fester, inflammation fades away and is cured.
The present invention can be summarized with others without prejudice to the concrete form of the spirit or essential characteristics of the present invention.Therefore, nothing
By from the point of view of which point, the embodiment above of the invention can only all be considered the description of the invention and can not limit invention,
Claims indicate the scope of the present invention, and above-mentioned explanation does not point out the scope of the present invention, therefore, with the present invention
The suitable implication and scope of claims in any change, be all considered as being included within the scope of the claims.
Claims (5)
1. a kind of Hibisci Paste with antiinflammatory action, it is characterised in that be prepared from by the raw material of following weight：Wooden cottonrose hibiscus
10-20 parts of Rong, 10-20 parts of gamboge, 10-15 parts of arisacma consanguineum schott, 6-12 parts of borneol, 5-12 parts of peppermint oil, vaseline 120-200
Part.
2. a kind of Hibisci Paste with antiinflammatory action according to claim 1, it is characterised in that by following weight
Raw material be prepared from：15-18 parts of cotton rose, 12-17 parts of gamboge, 12-15 parts of arisacma consanguineum schott, 8-10 parts of borneol, peppermint oil
7-9 parts, 120-160 parts of vaseline.
3. a kind of Hibisci Paste with antiinflammatory action according to claim 1, it is characterised in that by following weight
Raw material be prepared from：18 parts of cotton rose, 17 parts of gamboge, 15 parts of arisacma consanguineum schott, 9 parts of borneol, 8 parts of peppermint oil, vaseline 154
Part.
4. a kind of preparation method of Hibisci Paste with antiinflammatory action as described in claim 1-3 any one, its feature exists
In comprising the following steps：By the cotton rose, gamboge, arisacma consanguineum schott of above-mentioned weight with borneol and grinding into powder, then with weight
Part proportioning peppermint oil mixing, the vaseline after being well mixed again with weight modulates paste.
5. a kind of Hibisci Paste with antiinflammatory action according to claim 1-3 any one, it is characterised in that the cottonrose hibiscus
Rong's cream is applied to multi-infection and non-infection illness.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710464906.2A CN107029072A (en) | 2017-06-19 | 2017-06-19 | A kind of Hibisci Paste with antiinflammatory action |
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| CN201710464906.2A CN107029072A (en) | 2017-06-19 | 2017-06-19 | A kind of Hibisci Paste with antiinflammatory action |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412492A (en) * | 2017-09-14 | 2017-12-01 | 南通荣成医药化工有限公司 | A kind of Hibisci Paste of antiinflammatory action |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394009A (en) * | 2013-07-26 | 2013-11-20 | 徐心明 | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method |
| CN106166201A (en) * | 2016-03-24 | 2016-11-30 | 安徽中医药大学第附属医院 | A kind of Chinese medicinal ointment treating skin infection |
-
2017
- 2017-06-19 CN CN201710464906.2A patent/CN107029072A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103394009A (en) * | 2013-07-26 | 2013-11-20 | 徐心明 | Traditional Chinese medicine for treating trauma and diabetes foot ulcer and preparation method |
| CN106166201A (en) * | 2016-03-24 | 2016-11-30 | 安徽中医药大学第附属医院 | A kind of Chinese medicinal ointment treating skin infection |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412492A (en) * | 2017-09-14 | 2017-12-01 | 南通荣成医药化工有限公司 | A kind of Hibisci Paste of antiinflammatory action |
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