CN107013807A - GMP workshops carry pathogen tail gas discharge system technological design - Google Patents
GMP workshops carry pathogen tail gas discharge system technological design Download PDFInfo
- Publication number
- CN107013807A CN107013807A CN201710377344.8A CN201710377344A CN107013807A CN 107013807 A CN107013807 A CN 107013807A CN 201710377344 A CN201710377344 A CN 201710377344A CN 107013807 A CN107013807 A CN 107013807A
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- CN
- China
- Prior art keywords
- pathogen
- exhaust
- tail gas
- gas
- discharge
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D1/00—Pipe-line systems
- F17D1/02—Pipe-line systems for gases or vapours
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D3/00—Arrangements for supervising or controlling working operations
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F17—STORING OR DISTRIBUTING GASES OR LIQUIDS
- F17D—PIPE-LINE SYSTEMS; PIPE-LINES
- F17D3/00—Arrangements for supervising or controlling working operations
- F17D3/01—Arrangements for supervising or controlling working operations for controlling, signalling, or supervising the conveyance of a product
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treating Waste Gases (AREA)
Abstract
The invention discloses a kind of technological design that pathogen tail gas discharge system is carried based on live vaccine GMP workshops, being mainly used in GMP workshops, to contain pathogen active material cold（Heat）The nontoxic balance discharge of waste gas, it is characterised in that carry the design of pathogen exhaust emissions house steward's condensation water collection discharge technology and carry the nontoxic processing discharge technology design of pathogen tail gas terminal；Carrying pathogen exhaust emissions house steward's condensation water collection discharge technology design, condensation water collection process problem after the condensation of pathogen humid gas is carried for solving exhaust main in exhaust process；The nontoxic processing discharge technology design of carrying pathogen tail gas terminal, the nontoxic processing of pathogen gas end and balance emission problem are carried for solving exhaust main.
Description
Technical field
It is special the invention belongs to the technical field that live vaccine GMP workshops carry pathogen tail gas discharge system technological design
It is not that to contain pathogen active material for GMP workshops for animals cold（Heat）The nontoxic balance discharge of tail gas, active matter containing pathogen
Matter tail gas discharge system passes through valve, blower fan, sensor interlock, it is ensured that discharge tube pressure balance in whole system,
Gas-liquid separation is discharged and the nontoxic discharge of the tail gas of active material containing pathogen.
Background technology
At present, domestic veterinary biologicses enterprise cumulative year after year, the Ministry of Agriculture examines strict for the GMP of associated production enterprise
Degree rises, especially the control to GMP workshop Absolute Negative Pressures area, and the drainage exhaust in Absolute Negative Pressure area is related to biological peace
Entirely, and bio-safety be related to neighboring area environment, animal etc. safety, if outburst bio-safety event, consequence not it is contemplated that；
Therefore for GMP workshops of being involved in drug traffic, GMP laws and regulations requirements set up Absolute Negative Pressure area, and discarded object will be discharged after harmless treatment,
High-temperature sterilization is needed including wastewater and waste materials, waste gas, which need to ensure to remove after pathogen, to be discharged.Big department enterprise GMP workshops are definitely born at present
Nip exhaust uses three-dimensional exhaust gas treating device or double high efficiency filter biometric security devices, three-dimensional exhaust gas treating device floor space
Greatly, sterilization process uses industrial steam and NaOH solution, and NaOH solution changes frequent, and operating cost is higher, during long-play
Strict nontoxic discharge risk control difficulty is larger, and double high efficiency filter biometric security devices are modes popular at present, and
Increase gas-liquid separator at exhaust main, tail gas is discharged upwards, condensed water is discharged by waste pipe, this sets of plan needs increase
Gas-liquid separation device, accesses cooling water, and control is simple Mechanical course, does not also consider that exhaust main is micro- just to culture tank body
The influence of pressure.The present invention has subtracted gas-liquid separation device and chilled water unit, is filtered using double high efficiency filter biometric security devices
Tail gas containing pathogen, valve, blower fan, sensor interlock ensure the discharge tube pressure balance in whole system, and discharge is total
The design of pipe V-type ensures condensed water automatic back flow to condensed water hydrops pipeline, and it is unidirectional that tail gas condensing water collection pipe road installs gravity type additional
Valve realizes that condensed water is quantitatively discharged（Discharge tube is incorporated to the active-poison sewage inactivating device that workshop is carried）, it is total with reference to condensed water elimination
Pipe end air partition device avoids gas-liquid is counter from pushing up.Simultaneously solve tail gas of being involved in drug traffic it is nontoxic discharge, moisture condensed water quantitatively discharge,
The critical functions such as discharge manifold pressure balance.
The content of the invention
The purpose of the present invention be for current GMP workshops Absolute Negative Pressure area exhaust emissions technique weak point there is provided
It is a kind of to be designed by valve, blower fan, sensor interlock and pipeline V-type etc., it is ensured that the discharge tube pressure in whole system
The system of balance, gas-liquid separation discharge and the nontoxic discharge of waste gas containing active material, the purpose of the present invention is by following technical side
Case is realized：A kind of technological design that pathogen tail gas discharge system is carried based on live vaccine GMP workshops, its feature is existed
In including herein below：
Discharge manifold condensation water collection discharge technology designs and carried the nontoxic processing discharge technology design of pathogen tail gas terminal；Its
In,
Carrying pathogen exhaust emissions house steward's condensation water collection discharge technology design：
Step one：Absolute Negative Pressure area culture tank body passes through Stress control automatic-discharging tank body tail gas to exhaust main；
Step 2：High efficiency particulate air filter final vacuum blower fan starts, with exhaust main pressure-detecting device chain control；
Step 3：Tail gas condensing water passes through exhaust main V-type circuit design automatic back flow to condensation water collection pipeline；
Step 4：Condensed water elimination pipeline gravity-held check valve is supported the use with drain valve, quantitative automatic discharge；
The nontoxic processing discharge technology design of carrying pathogen tail gas terminal：
Step one：High efficiency particulate air filter final vacuum blower fan starts, with exhaust main pressure-detecting device chain control；
Step 2：Tail gas of being involved in drug traffic is by the nontoxic discharge of double high efficiency particulate air filters；
Step 3：Double high efficiency particulate air filters are configured with PAO detection mouths, filter sterilization interface, bio-safety sealing valve, it is ensured that efficiently
Strict integrality and sealing during filter service；
It is of the invention compared with existing traditional handicraft, have an advantageous effect in that：
1st, double high-performance bio security filters ensure that the nontoxic discharge for tail gas of being involved in drug traffic, and improve filtering accuracy；
2nd, PAO detection mouths, filter sterilization interface and the bio-safety sealing valve of configuration ensure that the integrality of high efficiency particulate air filter
And security and sealing when changing；
3rd, discharge manifold V-shape circuit design, it is ensured that humid gas natural cooling in discharge process, without unnecessary gas-liquid point
From auxiliary facilities such as device and cooling circulating waters；
4th, air exhauster and pipeline pressure detection device chain control, it is ensured that the culture requirement such as tank body pressure-fired or tiny structure；
5th, condensed water elimination valve and condensation water collection pipeline liquid level detection device chain control, it is to avoid condensate water discharging house steward
Return the risk of liquid/gas；
6th, whole tail gas discharge system of being involved in drug traffic uses automation control system, it is ensured that control accuracy and artifical influence factor.
Brief description of the drawings
Fig. 1 is to carry the nontoxic processing discharge technology of pathogen tail gas terminal；
Fig. 2 is bio-safety treatment process design enlarged drawing；
Fig. 3 is discharge manifold v-shaped tube road design technology；
Fig. 4 is the quantitative discharge technology Design enlargement figure of exhaust main condensation water collection,
In figure：AV1, AV2, AV3, AV4 are pneumatic diaphragm valve, and AV5 is biological airtight valve, and AHCU-1 is double high efficiency particulate air filter discharges
Device, P1 is pressure monitoring device, and VFD1 is frequency converter, and EAF1 is exhaust blower, and △ P1, △ P2 are pressure difference supervising device, and FLQ is
Separator, CV1 is gravity-held check valve.
Embodiment
When system is normally run：
1st, room technique culture tank body of being involved in drug traffic passes through pressure automatic control system emission；
2nd, exhaust blower EAF1 and exhaust main pressure-detecting device P1 chain controls, start-stop exhaust blower pressure is set according to exhaust main
Force value, blower fan rear end blast pipe place's mouth of pipe through walls is designed with fly net and stormproof louvre；
3rd, exhaust main tail gas passes through double high-effciency filter AHCU-1 and exhaust blower EAF1 emissions, double high efficiency particulate air filters
Front and rear configuration pressure monitor, main function monitoring high efficiency particulate air filter changes limit（During about 2 times of operation initial resistances）, high efficiency particulate air filter
Device is configured with PAO detection mouths and sterilization mouth, is sterilized before hunting leak and change to high efficiency particulate air filter, high-effciency filter front end
Bio-safety airtight valve AV5 is configured, front and rear gas pipeline is completely cut through during for maintenance efficient filter for installation；
4th, it is gathered in after exhaust main condensation water condensation in separator FLQ, gravity-held check valve is configured before line end drain valve
CV1, can both prevent condensed water to be responsible for anti-water/gas, can also quantify discharge condensed water, gravity-held check valve is determined according to process certification
CV1 type selectings；
System maintenance high efficiency particulate air filter：
1st, technique tank body exhaust stops, and closes valve AV1, AV4；
2nd, close the biological airtight valve AV5 of exhaust main, close blower fan EAF1；
The 3rd, formaldehyde disinfecting apparatus is accessed to effective filter AHCU-1 sterilization mouthful correspondence position, sets disinfecting time to start to disappear
Poison；
4th, new high efficiency particulate air filter is changed after the completion of sterilizing, high efficiency particulate air filter integrality is checked by PAO detection mouths；
5th, after the completion of changing, biological airtight valve AV5 is opened, blower fan EAF1, Open valve AV1, AV4 is opened.
Claims (4)
1. a kind of technological design that pathogen tail gas discharge system is carried based on live vaccine GMP workshops, it is characterised in that carry
Pathogen exhaust emissions house steward's condensation water collection discharge technology designs and carried the nontoxic processing discharge technology of pathogen tail gas terminal
Design；Carrying pathogen exhaust emissions house steward's condensation water collection discharge technology design, for solving exhaust main in exhaust
During carry condensation water collection process problem after the condensation of pathogen humid gas；The carrying nontoxic processing of pathogen tail gas terminal
Discharge technology is designed, and the nontoxic processing of pathogen gas end and balance emission problem are carried for solving exhaust main.
2. the technological design according to claim 1 that pathogen tail gas discharge system is carried based on live vaccine GMP workshops,
It is characterized in that, carrying pathogen exhaust emissions house steward's condensation water collection discharge technology design includes：
Pipeline distribution system unit, for being involved in drug traffic in live vaccine GMP workshops, region different process equipment gas exhaust piping collects tail
The technological design of gas discharge manifold and exhaust emissions house steward's pipeline technological design；
Condensation water collection exhaust unit, after hot gas condensation of being involved in drug traffic for exhaust main in exhaust process at condensation water collection
Reason.
3. the technological design according to claim 1 that pathogen tail gas discharge system is carried based on live vaccine GMP workshops,
It is characterized in that, the nontoxic processing discharge technology design of carrying pathogen tail gas terminal includes：
The nontoxic processing unit of pathogen gas end is carried, is retained for the pathogen in exhaust emissions house steward to be filtered；
Engine manifold balances exhaust unit, for discharging the gas after the harmless processing of terminal, while ensureing that exhaust main pressure is put down
Weighing apparatus.
4. a kind of technique as claimed in claim 1 for carrying pathogen tail gas discharge system based on live vaccine GMP workshops is set
The method of work of meter, it is characterised in that comprise the following steps：
Step 1：Region different process equipment tail gas of being involved in drug traffic in GMP workshops is collected to exhaust emissions respectively by respective gas exhaust piping
House steward；
Step 2：Exhaust main be involved in drug traffic in exhaust process hot gas condensation after condensed water by condensate return pipeline assemble to
Return line discharge opeing end, quantitative automatic can be discharged；
Step 3：Exhaust emissions house steward gas passes through pathogen in biometric security device filtering retention tail gas；
Step 4：Tail gas draws outdoor by exhaust blower after pathogen filtering retention in tail gas, and ensures tail gas exhaust main pressure
Balance.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710377344.8A CN107013807A (en) | 2017-05-25 | 2017-05-25 | GMP workshops carry pathogen tail gas discharge system technological design |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710377344.8A CN107013807A (en) | 2017-05-25 | 2017-05-25 | GMP workshops carry pathogen tail gas discharge system technological design |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107013807A true CN107013807A (en) | 2017-08-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710377344.8A Pending CN107013807A (en) | 2017-05-25 | 2017-05-25 | GMP workshops carry pathogen tail gas discharge system technological design |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202020933U (en) * | 2011-03-25 | 2011-11-02 | 牡丹江佰佳信生物科技有限公司 | Odor removing device for high-altitude exhaust of fermentation tail gas |
| CN202052450U (en) * | 2011-05-17 | 2011-11-30 | 天津中天海盛环保科技有限公司 | Tail gas treatment system of membrane bioreactor |
| CN103418204A (en) * | 2013-08-09 | 2013-12-04 | 中国中轻国际工程有限公司 | Tail gas treatment process for biological aerobic fermentation tank and equipment system thereof |
| CN203710871U (en) * | 2014-02-13 | 2014-07-16 | 内蒙古必威安泰生物科技有限公司 | Medicine production waste gas processor |
| US20150090116A1 (en) * | 2013-09-27 | 2015-04-02 | L'air Liquide, Societe Anonyme Pour I'etude Et I'exploitation Des Procedes Georges Claude | On-site medical gas production plant and associated operating method |
| CN104801147A (en) * | 2015-04-24 | 2015-07-29 | 桂林汇众化工设备有限公司 | Man-made board glue-making tail gas treatment process and system |
| CN106377972A (en) * | 2016-11-14 | 2017-02-08 | 安徽名杰净化科技有限公司 | Gas sterilization discharging device for GMP workshop |
-
2017
- 2017-05-25 CN CN201710377344.8A patent/CN107013807A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202020933U (en) * | 2011-03-25 | 2011-11-02 | 牡丹江佰佳信生物科技有限公司 | Odor removing device for high-altitude exhaust of fermentation tail gas |
| CN202052450U (en) * | 2011-05-17 | 2011-11-30 | 天津中天海盛环保科技有限公司 | Tail gas treatment system of membrane bioreactor |
| CN103418204A (en) * | 2013-08-09 | 2013-12-04 | 中国中轻国际工程有限公司 | Tail gas treatment process for biological aerobic fermentation tank and equipment system thereof |
| US20150090116A1 (en) * | 2013-09-27 | 2015-04-02 | L'air Liquide, Societe Anonyme Pour I'etude Et I'exploitation Des Procedes Georges Claude | On-site medical gas production plant and associated operating method |
| CN203710871U (en) * | 2014-02-13 | 2014-07-16 | 内蒙古必威安泰生物科技有限公司 | Medicine production waste gas processor |
| CN104801147A (en) * | 2015-04-24 | 2015-07-29 | 桂林汇众化工设备有限公司 | Man-made board glue-making tail gas treatment process and system |
| CN106377972A (en) * | 2016-11-14 | 2017-02-08 | 安徽名杰净化科技有限公司 | Gas sterilization discharging device for GMP workshop |
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Application publication date: 20170804 |