CN106990232B - Blood Kit analysis system and analysis method - Google Patents
Blood Kit analysis system and analysis method Download PDFInfo
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- CN106990232B CN106990232B CN201710300287.3A CN201710300287A CN106990232B CN 106990232 B CN106990232 B CN 106990232B CN 201710300287 A CN201710300287 A CN 201710300287A CN 106990232 B CN106990232 B CN 106990232B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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Abstract
The optical signal intensity of a kind of Blood Kit analysis system and analysis method, the variation generated by analysis area measures, and determines the parameter of blood sample, is analyzed by the error result for redundant measurement channel, provides its reliable measured value.
Description
Technical field
The present invention relates to a kind of bodily fluid analysis systems, more particularly, to a kind of blood analysis system and analysis method.
Background technique
Body fluid refers to all types of liquids including containing in human body or animal body, generally include whole blood, lymph,
Urine, saliva, sweat etc. relate generally to the blood and urine of human body in clinicing aspect.
In chemistry or clinicing aspect, it is extremely important for carrying out quantitative or qualitative analysis to analyte contained in blood sample
's.Pathological state and targetedly and base can early and reliably be found out in clinical diagnosis by testing to blood liquid
It is to do an inspection ahead of time to the hiding disease in each human body that the pass physical condition, which in fact of case is monitored, in the screening of blood
It surveys, can carry out when any detection indicates abnormal, that is, indicating personal body in relation to the detection in function index for various compositions
Body has gone out certain some defect, it is necessary to which a treatment is done in the morbidity and early stage for preventing disease ahead of time.
In blood analysis detection, the accuracy about measurement result is major issue in need of consideration.Particularly with true
The detection for determining the glucose content in blood, since it is the basis that diabetic uses insulin dose, measurement result
Need to guarantee as far as possible the accuracy of measurement result.
In order to realize that the reliability of measurement result, the patent of invention of 200810215254.X pass through in blood analysis system
The assessment channel of redundancy is set, when being greater than predetermined value by the measurement result deviation of the analysis system, provides the analysis system
The information of measurement result mistake, to ensure that the accurate of measured value.But due to increasing redundancy in wherein analysis system,
As long as there is mistake in a Measurement channel in analysis system, even if another Measurement channel is accurate, then measurement result
It will appear deviation, which will provide the information of measurement result mistake, at this moment need to re-start test.That is the redundancy
The setting in channel increases the probability that system provides measurement result mistake, to need to retest, increases the burden of patient.
Summary of the invention
Improvement of the present invention as the patent of invention of 200810215254.X, is able to solve the above problem of the prior art,
It is cited in full text in this.
As one aspect of the present invention, a kind of Blood Kit analysis method is provided, includes the following steps: (1) blood sample
Product and reagent react in the first analysis area and the second analysis area；(2) pass through the first analog signal measuring unit and the
Two analog signal measuring units generate the analog signal of the first analysis area and the second analysis area；(3) pass through the first analog-to-digital conversion
Device and the second analog-digital converter are based on above-mentioned analog signal and generate the first digital signal and the second digital signal respectively；(4)
The first digital signal and the second digital signal are stored by memory；(5) single by the first assessment unit and the second assessment
Member generates the first measured value and the second measured value of blood sample based on above-mentioned first digital signal and the second digital signal；
(6) comparator unit is compared the first measured value and the second measured value, determines whether its deviation is greater than specific threshold；
(6.1) if the deviation is less than specific first threshold, analysis result generation unit uses the first measured value and the second measured value
In any one as measurement result value, terminate this measurement；(6.2) it if the deviation is greater than specific first threshold, carries out
Step (7)；(7) comparator unit compares the first digital signal and the second digital signal in memory, judges the first number
Whether the deviation of signal and the second digital signal is less than specific second threshold；(7.1) if the deviation is greater than specific second threshold
Value, then analyze the information that result generation unit provides this measurement result mistake；(7.2) if the deviation is less than specific second threshold
Value carries out step (8)；(8) the first digital signal is inputted by the second assessment unit, the input of the second digital signal by control unit
First assessment unit；Second assessment unit is based on the first digital signal and generates third measured value, first assessment unit
The 4th measured value is generated based on the second digital signal；(9) comparator unit is respectively compared first measured value and described
Deviation S1, second measured value between the four measured values and deviation S2 between the 4th measured value: if only S1
Less than specific first threshold, then analyzes result generation unit and provide measurement of first measured value as this blood sample
Value；If only S2 is less than specific first threshold, analyzes result generation unit and provide second measured value as this blood
The measured value of liquid sample；Otherwise, analysis result generation unit provides the information of this measurement result mistake.
As another aspect of the present invention, the analysis system for above-mentioned Blood Kit analysis method is provided, comprising:
Reagent system, the first analysis area, the second analysis area, the first analog signal measuring unit, the second analog signal measuring unit, first
Analog-digital converter, the second analog-digital converter, the first assessment unit, the second assessment unit, memory, analyze result generation unit with
And control unit.
Preferably, first analysis area and the second analysis area are respectively used to blood sample and occur wherein with reagent
Reaction；The first analog signal measuring unit and the second analog signal measuring unit, be based respectively on the first analysis area and
The reaction of second analysis area generates analogue measurement signal；First analog-digital converter and the second analog-digital converter respectively will
First analog signal and the second analog signal are digitized, and the first digital signal and the second digital signal are generated；It is described
First assessment unit and the second assessment unit are based respectively on what the first analog-digital converter and the second analog-digital converter generated
The first measured value and the second measured value of digital signal generation blood sample；Comparator unit, can be for the first assessment
The first measured value and the second measurement that unit and the second assessment unit generate are compared: analysis result generation unit,
Generate the analysis result of single measurement；Memory can store the first digital signal and the second digital signal；Control is single
Member can control the input signal of the first assessment unit and the second assessment unit；When the comparator unit first measures
Deviation between value and the second measured value is greater than specific first threshold, and the comparator unit can be in the memory
The first digital signal and the second digital signal, judge the deviation of measurement result whether from assessment unit based on this comparison
Deviation；If the deviation of first digital signal and the second digital signal is greater than specific second threshold, measurement knot is judged
The deviation of fruit is not from assessment unit, and the analysis result generation unit provides the information of this measurement result mistake；If
The deviation of first digital signal and the second digital signal is less than second threshold, then judges that the deviation of measurement result carrys out self-appraisal
Estimate unit, according to first digital signal, the second digital signal, the first measured value and the second measured value, the analysis knot
Fruit generation unit provide in first measured value and the second measured value measurement result correctly value as this blood sample
Measured value.
Detailed description of the invention
Fig. 1 is the schematic diagram of the Blood Kit analysis system of the embodiment of the present invention.
Fig. 2 is the flow chart of the Blood Kit analysis method of the embodiment of the present invention.
Specific embodiment
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention without any creative labor, may be used also for those of ordinary skill in the art
To obtain other drawings based on these drawings.
The Blood Kit analysis system of the embodiment of the present invention, as shown in Figure 1, including reagent system (not shown), first point
Analyse area 1a and the second analysis area 1b, the first analog signal measuring unit 2a and the second analog signal measuring unit 2b, first
Analog-digital converter 3a and the second analog-digital converter 3b, the first assessment unit 4a and the second assessment unit 4b, comparator unit
5, memory 6, control unit 7 analyzes result generation unit 8.
Reagent system is used to be used for the input of Blood Kit analysis system and reaction of blood, forms the object of reaction blood parameters
Reason amount can pass through the survey of the physical quantity by the model of the measured value and blood parameters after the measured value measurement of the physical quantity
Magnitude determines blood parameters.Measured blood parameters can be such as blood-sugar content or cholesterol level.
First analysis area 1a and the second analysis area 1b is of similar shape and conversion zone, receive respectively input its
In identical type dosage blood sample and reagent, thus make blood sample and reagent in each analysis area with reagent send out
Raw reaction.The reaction of generation is to be capable of providing the reaction process of blood parameters value, such as can provide the anti-of optical change signal
It answers, is also possible to electrochemical reaction.
First analog signal measuring unit 2a and the second analog signal measuring unit 2b, is based respectively on the first analysis area 1a
And second analysis area 1b reaction generate analogue measurement signal.Wherein, measuring unit is corresponding to analysis area reaction type
Measuring cell, for example, analysis area generate be the optical signalling of variation when, measuring unit can make such as optical strength measurement single
Member；When electrochemical reaction occurring in analysis area, measuring unit be can be such as voltage or current sensor.
First analog-digital converter 3a and the second analog-digital converter 3b respectively surveys the first analog signal measuring unit 2a
First analog signal of amount and the second analog signal of the first analog signal measuring unit 2a measurement are digitized, and generate the
One digital signal and the second digital signal.
First assessment unit 4a and the second assessment unit 4b, passes through respective model respectively, based on the first number letter
Number and the second digital signal determine the first measured value and the second measured value of blood sample.Memory 6 can store first
Digital signal and the second digital signal.Control unit 7 can read the first digital signal and second in memory 6
Digital signal, and can be to the input digital signal of control the first assessment unit 4a and the second assessment unit 4b.Analysis knot
Fruit generation unit 8 generates the analysis result of single measurement.
The Blood Kit analysis method of the embodiment of the present invention includes the following steps: (1) blood sample and reagent at first point
Analysis area 1a and the second analysis area 1b reacts；(2) pass through the first analog signal measuring unit 2a and the second analog signal
The analog signal of 2b measuring unit generation the first analysis area 1a and the second analysis area 1b；(3) pass through the first analog-digital converter 3a
And second analog-digital converter 3b be based on above-mentioned analog signal generate the first digital signal and the second digital signal respectively；(4)
The first digital signal and the second digital signal are stored by memory 6；(5) pass through the assessment of the first assessment unit 4a and second
Unit 4b generates the first measured value and the second survey of blood sample based on above-mentioned first digital signal and the second digital signal
Magnitude；(6) comparator unit 5 is compared the first measured value and the second measured value, and it is specific to determine whether its deviation is greater than
Threshold value；(6.1) if the deviation is less than specific first threshold, analysis result generation unit 8 uses the first measured value and second
Any one in measured value terminates this measurement as measurement result value；(6.2) if the deviation is greater than specific first threshold
Value carries out step (7)；(7) comparator unit 5 compares the first digital signal and the second digital signal in memory 6, judgement
Whether the deviation of the first digital signal and the second digital signal is less than specific second threshold；(7.1) if the deviation is greater than spy
Determine second threshold, then analyzes the information that result generation unit 8 provides this measurement result mistake；(7.2) if the deviation is less than
Specific second threshold indicates that the deviation derived from assessment unit, carries out step (8)；(8) first number is believed by control unit 7
Number input the second assessment unit 4b, the second digital signal input the first assessment unit 4a；Second assessment unit 4b is based on the first number
Word signal generates third measured value, and the first assessment unit 4a is based on the second digital signal and generates the 4th measured value；(9) comparator list
Member 5 is respectively compared deviation S1, second measured value and institute between first measured value and the 4th measured value
State the deviation S2:(9.1 between the 4th measured value) if only S1 is less than specific first threshold, indicate that the first assessment unit 4a gives
Measured value out is credible, then analyzes result generation unit 8 and provide measured value of first measured value as this blood sample；
(9.2) if only S2 is less than specific first threshold, the measurement result for indicating that the second assessment unit 4b is provided is credible, then analyzes knot
Fruit generation unit 8 provides measured value of second measured value as this blood sample；(9.3) otherwise, expression can not determine
Whether the result that the first assessment unit 4a and the second assessment unit 4b are provided is credible, and analysis result generation unit 8 provides this
The information of measurement result mistake.
The above is only the preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-described embodiment,
All technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.For the ordinary skill people of the art
For member, several improvements and modifications without departing from the principles of the present invention should be regarded as falling into protection scope of the present invention.
Claims (2)
1. a kind of Blood Kit analysis method includes the following steps: (1) blood sample and reagent in the first analysis area and second
Analysis area reacts；First analysis area and the second analysis area is of similar shape and conversion zone, receives defeated respectively
Enter the blood sample and reagent of identical type dosage therein；(2) pass through the first analog signal measuring unit and the second mould
Quasi- signal measurement unit generates the analog signal of the first analysis area and the second analysis area；Wherein, what analysis area generated is variation
Optical signalling, measuring unit is optical strength measuring unit；(3) pass through the first analog-digital converter and the second analog-digital converter
The first digital signal and the second digital signal are generated respectively based on above-mentioned analog signal；(4) pass through the first number of memory storage
Word signal and the second digital signal；(5) above-mentioned first number letter is based on by the first assessment unit and the second assessment unit
Number and the second digital signal generate blood sample the first measured value and the second measured value；(6) comparator unit is to first
Measured value and the second measured value are compared, and determine whether its deviation is greater than specific threshold；(6.1) if the deviation is less than spy
Determine first threshold, analysis result generation unit use any one in the first measured value and the second measured value as measuring knot
Fruit value terminates this measurement；(6.2) it if the deviation is greater than specific first threshold, carries out step (7)；(7) comparator unit ratio
Compared with the first digital signal and the second digital signal in memory, the inclined of the first digital signal and the second digital signal is judged
Whether difference is less than specific second threshold；(7.1) it if the deviation is greater than specific second threshold, analyzes result generation unit and provides
The information of this measurement result mistake；(7.2) it if the deviation is less than specific second threshold, carries out step (8)；(8) pass through control
First digital signal is inputted the second assessment unit by unit processed, and the second digital signal inputs the first assessment unit；Described second comments
Estimate unit and be based on the first digital signal generation third measured value, first assessment unit is based on the second digital signal and generates the 4th
Measured value；(9) comparator unit is respectively compared deviation S1 between first measured value and the 4th measured value, described
Deviation S2:(9.1 between second measured value and the 4th measured value) if only S1 is less than specific first threshold, divide
Analysis result generation unit provides measured value of first measured value as this blood sample；(9.2) if only S2 is less than
Specific first threshold then analyzes result generation unit and provides measured value of second measured value as this blood sample；
(9.3) otherwise, analysis result generation unit provides the information of this measurement result mistake.
2. a kind of Blood Kit analysis system is used for Blood Kit analysis method described in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710300287.3A CN106990232B (en) | 2016-01-01 | 2016-01-01 | Blood Kit analysis system and analysis method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610000339.0A CN105388276B (en) | 2016-01-01 | 2016-01-01 | A kind of Blood Kit analysis system and analysis method |
| CN201710300287.3A CN106990232B (en) | 2016-01-01 | 2016-01-01 | Blood Kit analysis system and analysis method |
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| CN201610000339.0A Division CN105388276B (en) | 2016-01-01 | 2016-01-01 | A kind of Blood Kit analysis system and analysis method |
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| CN106990232A CN106990232A (en) | 2017-07-28 |
| CN106990232B true CN106990232B (en) | 2019-05-28 |
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| CN201710300287.3A Active CN106990232B (en) | 2016-01-01 | 2016-01-01 | Blood Kit analysis system and analysis method |
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| CN108107195B (en) * | 2017-12-16 | 2019-09-24 | 山东卫康医学检验有限公司 | Blood sample analysis test method |
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| CN1735375A (en) * | 2001-01-02 | 2006-02-15 | 特拉森斯公司 | Analyte monitoring device and methods of using the same |
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| CN104569097B (en) * | 2014-12-17 | 2018-01-12 | 浙江理工大学 | The preparation method and applications of copper nano-wire graphene complex modified electrode |
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2016
- 2016-01-01 CN CN201610000339.0A patent/CN105388276B/en not_active Expired - Fee Related
- 2016-01-01 CN CN201710300287.3A patent/CN106990232B/en active Active
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| CN86105980A (en) * | 1986-09-09 | 1988-03-23 | 顾涵森 | Bioelectric signal measuring apparatus |
| JP2012147451A (en) * | 1998-09-15 | 2012-08-02 | In Touch Technologies Ltd | Service provision method and service platform |
| CN1735375A (en) * | 2001-01-02 | 2006-02-15 | 特拉森斯公司 | Analyte monitoring device and methods of using the same |
| WO2009057525A1 (en) * | 2007-10-29 | 2009-05-07 | Sysmex Corporation | Cell analysis apparatus and cell analysis method |
| CN102046076A (en) * | 2008-04-03 | 2011-05-04 | Kai医药公司 | Non-contact physiologic motion sensors and methods for use |
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| WO2015148112A1 (en) * | 2014-03-26 | 2015-10-01 | Ethicon Endo-Surgery, Inc. | Surgical instrument comprising a sensor system |
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| Publication number | Publication date |
|---|---|
| CN105388276B (en) | 2017-08-04 |
| CN106990232A (en) | 2017-07-28 |
| CN105388276A (en) | 2016-03-09 |
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