CN106963679A

CN106963679A - One kind calm the nerves itching-relieving shower breast

Info

Publication number: CN106963679A
Application number: CN201710196554.7A
Authority: CN
Inventors: 杨凯
Original assignee: Foshan Harvest Chemical Technology Co Ltd
Current assignee: Foshan Harvest Chemical Technology Co Ltd
Priority date: 2017-03-28
Filing date: 2017-03-28
Publication date: 2017-07-21

Abstract

The invention discloses one kind calm the nerves itching-relieving shower breast, contain 0.03~1 part of Phellinus linteus extract during itching-relieving shower of calming the nerves is newborn, 0.05~1.6 part of Flos Campsis extract, 0.07~2 part of gorgonian extract, it is only to play a part of cleaning mostly instant invention overcomes current bath oil, the shortcoming of single effect, with anti-bacterial, anti-itching and efficacy of tranquilizing mind and improving sleeping.

Description

One kind calm the nerves itching-relieving shower breast

Technical field

The present invention relates to household chemicals field, and in particular to one kind calm the nerves itching-relieving shower breast.

Background technology

Bath oil, a kind of liquid ceanser used when being and having a bath.It is excellent that bath oil is not stimulated gently because of it, fragrance is pleasant etc. Point, is generally used when having a bath by people, gradually instead of perfumed soap.Because bath oil is liquid, various functions can be conveniently added Property ingredient, however as the development of society, the pollution of environment is increasingly severe, and the particulate in air is attached to skin surface, Pruitus is easily caused, or even causes allergy, current bath oil is only to play a part of cleaning, effect list mostly One, it is impossible to meet the demand in daily life, thus be badly in need of exploitation it is a kind of can effectively anti-bacterial, anti-itching with multi-efficiency Bath oil.

The content of the invention

Based on this, it is an object of the invention to provide a kind of antipruritic wash one's hair of calming the nerves with anti-bacterial, anti-itching and efficacy of tranquilizing mind and improving sleeping The newborn bath oil of bath.

In order to achieve the above object, the present invention provides following technical scheme：

One kind calms the nerves itching-relieving shower breast by weight including following components：0.03~1 part of Phellinus linteus extract, is insulted 0.05~1.6 part of clouds flower extract, 0.07~2 part of gorgonian extract.

The preparation method of the Phellinus linteus extract is：Phellinus linteus is dried, 60~80 mesh were crushed Sieve, by solid-liquid ratio 1：(10~20) 55~85% ethanol are added, in 70~90 DEG C of water-bath backflow 3h, filtering, filter residue repeats above-mentioned Operation once, merges extract solution twice, then the concentration of rotated evaporation under reduced pressure.

The preparation method of the Flos Campsis extract is：Chinese trumpet creeper is cleaned into drying, 20~40 mesh sieves were crushed, by feed liquid Than 1：(10~20) ethanol for adding 50~90% soaks 30~60min, 1~2h of ultrasonic extraction, filters to obtain extract solution, filter residue is again 1h is extracted with EtOH Sonicate, is filtered to get filtrate, merges filtrate twice, rotated evaporation under reduced pressure concentration.

The preparation method of the gorgonian is：Gorgonian is cleaned into drying, 60~80 mesh sieves were crushed, plus 70~90% second Alcohol, in 40~50 DEG C of water-bath 0.5~1.5h of refluxing extraction, then be centrifuged (rotating speed 3500r/min, the time 30~ 60min), supernatant, rotated evaporimeter concentration are taken.

The present invention calms the nerves, and itching-relieving shower is newborn to be made up of the component of following mass percent：

The newborn part material of itching-relieving shower of calming the nerves to the present invention makees following introduce：

Phellinus linteus extract：Phellinus linteus main chemical compositions are fructification, mycelium and zymotic fluid In exocellular polysaccharide, in addition with flavones and its derivative, Coumarins, phytosterin compound；And phellinus linteus is always yellow Ketone has very strong removing DPPH, O2- and OH ability, when the concentration of phellinus linteus general flavone is 76.6 μ g/ During ml, its clearance rate highest to DPPH, is 92.57%；Afterwards, with the increase of general flavone concentration, clearance rate progressively under Drop.

Flos Campsis extract：Chinese trumpet creeper is Bignoniaceae, category of reaching the clouds climbs up by holding on to liana, Classification system：(Campsis Grandiflora central China, property happiness warm and moist, the environment for having sunlight, slightly resistance to shade) are distributed in；Flos Campsis extract is main For triterpenes, phenylpropyl alcohol alcohols, flavonoids, anthocyanidin and volatile oil etc.；Hexamethylene alcohol compound in Flos Campsis extract Rengyolone suppresses the generation and expression of derivable NO synthase in the RAW264.7 cells that lipopolysaccharides (LPS) is stimulated, and Suppress TNF-α and COX-2 expression.Its mechanism is probably to lower NF- kB activities, and hinders p38MAPK activity, so as to rise To the effect of anti-inflammatory；Flos Campsis extract is to Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus Five kinds of bacteriums such as bacterium, Escherichia coli and salmonella are respectively provided with good inhibiting effect；General flavone has in Flos Campsis extract Very strong Scavenging ability.Flos Campsis extract expands thin vessels caliber, and increase capillary network crosspoint suppresses red thin Born of the same parents and platelet aggregation, reduce blood viscosity, with the effect of blood microcirculation is improved, reach the effect of sleeping.

Gorgonian extract：Gorgonian extract has certain antibacterial work to Vibrio anguillarum, Vibrio harveyi and vibrio alginolyticus Property, and the bacteriostatic activity of petroleum ether is relative better than other solvents；Ethyl acetate solvent extract solution is then molten to clam worm vibrios and pair Blood vibrios shows faint bacteriostatic activity；Gorgonian extract has to remove well to hydroxy radical and DPPH free radicals to be made With.

Compared with prior art, the method have the advantages that

(1) blood-promoting and mind-easing that Flos Campsis extract plays the role of, present invention itching-relieving shower breast of calming the nerves can help for sleep.

(2) cracked feet in itching-relieving shower breast of the invention of calming the nerves in Flos Campsis extract, compounding Phellinus linteus extract Terpene, steroid and cholesterolic materials in Phellinus, compounding gorgonian extract, Synergistic, gorgonian extract, split Flavonoid substance cooperates with anti-aging with Chinese trumpet creeper in hoof Phellinus extract, and subergorgic acid and the Chinese trumpet creeper of gorgonian extract are carried Take thing synergetic antibacterial effect；Make itching-relieving shower breast of the invention of calming the nerves that not only there is the effect of good anti-inflammation, also with one Fixed senile-resistant efficacy and good sleeping effect.

(3) present invention calms the nerves, and itching-relieving shower is newborn, and green safety is gentle non-stimulated.

Embodiment

Below in conjunction with specific embodiment, the present invention is further elaborated.The present invention of embodiment 1~5 calm the nerves itching-relieving shower breast Formula is shown in Table one

Table one

The preparation method of the Phellinus linteus extract is：Phellinus linteus is dried, 80 mesh sieves was crushed, and pressed Solid-liquid ratio 1：20 add 85% ethanol, in 90 DEG C of water-bath backflow 3h, and filtering, filter residue repeats aforesaid operations once, and merging is carried twice Take liquid, then the concentration of rotated evaporation under reduced pressure.

The preparation method of the Flos Campsis extract is：Chinese trumpet creeper is cleaned into drying, 20~40 mesh sieves were crushed, by feed liquid Than 1：10 add 50% ethanol immersion 60min, ultrasonic extraction 2h, filter to obtain extract solution, filter residue extracts 1h with EtOH Sonicate again, Filter to get filtrate, merge filtrate twice, rotated evaporation under reduced pressure concentration.

The preparation method of the gorgonian is：Gorgonian is cleaned into drying, 60~80 mesh sieves, plus 90% ethanol was crushed, In 50 DEG C of water-bath refluxing extraction 0.5h, then it is centrifuged (rotating speed 3000r/min, time 60min), takes supernatant, through rotation Turn evaporimeter concentration.

Comparative example 1

Difference with embodiment 1 is not add Phellinus linteus extract, other preparation conditions and method and embodiment 1 It is identical.

Comparative example 2

Difference with embodiment 1 is not add Flos Campsis extract, and other preparation conditions and method are same as Example 1.

Comparative example 3

Difference with embodiment 1 is not add gorgonian extract, and other preparation conditions and method are same as Example 1.

Comparative example 4

Difference with embodiment 1 is to add 0.02 part of plant composition, other preparation conditions and method and the phase of embodiment 1 Together.

Comparative example 5

Difference with embodiment 1 is to add 0.9 part of plant composition, and other preparation conditions and method are same as Example 1.

Comparative example 6

Difference with embodiment 1 is not add plant composition, and other preparation conditions and method are same as Example 1.

Compliance test result：

Detection results on probation are carried out to product prepared by embodiment 1-5 and comparative example 1-6, while being declared with a commercially available With antipruritic effect bath foam of calming the nerves for control group.140 people are randomly selected to embodiment 1~5, comparative example 1~6 and comparative example Tried out with commercially available product product, altogether using 1 month.Result on trial is counted, every using effect total score is 5 points：5 points are highest Point, represent fine；4 points are preferable；3 points are to receive；2 points are bad；1 point is to receive.It is averaged below to be every Point, result on trial refers to table two：

Table two

It can show that the present invention each plant component of itching-relieving shower breast of calming the nerves has cooperative effect, and this hair by above-mentioned use result Bright formulation ratio span is better than other spans, and using effect is good.In a word, it the foregoing is only the preferable of the present invention Embodiment, all equivalent changes and modifications made according to scope of the present invention patent, should all belong to the covering scope of patent of the present invention.

Claims

The itching-relieving shower breast 1. one kind is calmed the nerves, it is characterised in that the bath oil includes following components by weight：Phellimls hole 0.03~1 part of fungus extract, 0.05~1.6 part of Flos Campsis extract, 0.07~2 part of gorgonian extract.
The itching-relieving shower breast 2. one kind according to claim 1 is calmed the nerves, it is characterised in that the Phellinus linteus extract Preparation method be：Phellinus linteus is dried, 60~80 mesh sieves were crushed, by solid-liquid ratio 1：(10~20) add 55~ 85% ethanol, in 70~90 DEG C of water-bath backflow 3h, filtering, filter residue repeats aforesaid operations once, merges extract solution twice, then through rotation Turn evaporation under reduced pressure concentration.
The itching-relieving shower breast 3. one kind according to claim 1 is calmed the nerves, it is characterised in that the preparation of the Flos Campsis extract Method is：Chinese trumpet creeper is cleaned into drying, 20~40 mesh sieves were crushed, by solid-liquid ratio 1：(10~20) ethanol of addition 50~90% 30~60min, 1~2h of ultrasonic extraction are soaked, extract solution is filtered to obtain, filter residue extracts 1h with EtOH Sonicate again, filtered to get filtrate, closes And filtrate twice, rotated evaporation under reduced pressure concentration.
The itching-relieving shower breast 4. one kind according to claim 1 is calmed the nerves, it is characterised in that the preparation method of the gorgonian For：Gorgonian is cleaned into drying, 60~80 mesh sieves were crushed, plus 70~90% ethanol, in 40~50 DEG C of water-bath refluxing extractions 0.5 ~1.5h, then be centrifuged (rotating speed 3500r/min, 30~60min of time), take supernatant, rotated evaporimeter concentration .
The itching-relieving shower breast 5. one kind according to claim 1 is calmed the nerves, it is characterised in that the bath oil is by following quality hundred Divide the component composition of ratio：