CN106963543A - Conduction type flexible miniature support and medicine equipment - Google Patents
Conduction type flexible miniature support and medicine equipment Download PDFInfo
- Publication number
- CN106963543A CN106963543A CN201710084146.2A CN201710084146A CN106963543A CN 106963543 A CN106963543 A CN 106963543A CN 201710084146 A CN201710084146 A CN 201710084146A CN 106963543 A CN106963543 A CN 106963543A
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- CN
- China
- Prior art keywords
- drainage tube
- conduction type
- medicine
- type flexible
- cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
Abstract
The present invention relates to technical field of medical instruments, more particularly, to a kind of conduction type flexible miniature support and medicine equipment, drainage tube including multi-cavity, the drainage tube of the multi-cavity is passed through along the path entered from the scleral spur of anterior chamber's eyes in epichoroidal space, wherein, the drainage tube of the multi-cavity at least includes a fluid passage, multiple medicine filled cavities and multiple medicine filled cavities, the miniature support is passed through along the path entered from the scleral spur of anterior chamber's eyes in epichoroidal space, the fluid passage of miniature support is by guiding the aqueous humor inflow epichoroidal space of anterior chamber to reach the purpose of reduction intraocular pressure.Meanwhile, medicine filled cavity can effectively, enduringly in fixed position be discharged medicine, be greatly reduced fixed position propagation and the situation of inflammation.
Description
Technical field
The present invention relates to technical field of medical instruments, more particularly, to a kind of conduction type flexible miniature support and Medical treatment device
Tool.
Background technology
At present, glaucoma is a kind of increased disease of the aqueous humor in eyes.In the eyes of health, ciliary process secretion room
Water, then angle of the aqueous humor through cornea and iris.Glaucoma appears to be the result of trabecular network obstruction.Such obstruction can
To be caused by cell or coming off for other remains.When aqueous humor is not discharged suitably from the net of obstruction, it will increase and make
Into in eyes, particularly leading to increasing for the pressure on the blood vessel of optic nerve.High pressure on blood vessel can cause retina neural
Ganglion cell is dead, and ultimately results in blindness.
In correlation technique, for glaucoma surgical operation therapy when a kind of drainage system or shunting can be implanted into eye
Pipe.The effect of the drainage system is to discharge aqueous humor from anterior chamber, so as to reduce intraocular pressure.The drainage system is typically with wound
Property surgical method and be implanted into.Performed the operation according to as one, a thin slice is formed in surgery mode in sclera.The thin slice
Fold back to form a small cavity, an isocon is embedded in eye by the thin slice.Such operation can be because of its implant
It is big and have stronger traumatic, and various adverse events can be caused, such as infection and scar result in the need for re-starting
Operation.
There is some shortcomings, and only medium success rate currently used for the device and process for the treatment of glaucoma.It is this
Process has very big wound to eyes, also requires point-device Surgical technique, for example, be properly positioned and draw in position
Flow device.In addition, this device of the drainage of bubble easily causes infection under from anterior chamber to the conjunctiva under sclera thin slice, and
And may block and stop operation.This may require re-starting operation removing the device, and place another device, or
Further surgical operation can be caused.In view of above-mentioned reason, it is necessary to be modified to the apparatus and method for treating glaucoma.
Certainly, some patent documents also refer to the introduction of similar drainage tube in correlation technique, with reference to shown in Fig. 1, shunting
Pipe 105 is arranged in eyes, and aqueous humor flows to epichoroidal space after entering isocon 105 from anterior chamber 115.But, the isocon is only
Only it is to provide a fluid passage, there is following two point defect：
First, single-chamber isocon is implanted with to deform upon under the pressure of muscle for a long time, causes tube chamber to cave in stifled
Plug；
2nd, isocon is after the implantation, it is possible to local location can be caused to occur propagation and the situation of inflammation, produces other
Lesion.
The content of the invention
It is an object of the invention to provide a kind of conduction type flexible miniature support and medicine equipment, to solve in the prior art
The single-chamber isocon of presence is implanted with to deform upon under the pressure of muscle for a long time, causes tube chamber to cave in blocking；Point
Flow tube is after the implantation, it is possible to local location can be caused to occur propagation and the situation of inflammation, and the technology for producing other lesions is asked
Topic.
In order to solve the above technical problems, the present invention provides a kind of conduction type flexible miniature support, it includes drawing for multi-cavity
Flow tube, the drainage tube of the multi-cavity is passed through along the path entered from the scleral spur of anterior chamber's eyes in epichoroidal space, wherein,
The drainage tube of the multi-cavity at least includes：
One fluid passage, through of the fluid passage along the drainage tube is set, and it has inflow entrance and stream
Outlet；
Multiple medicine filled cavities, multiple medicine filled cavities are arranged at the periphery of the fluid passage, and respectively along institute
The circumferential insertion for stating drainage tube is set；
Multiple drug releasing pores, multiple drug releasing pores are opened on the outer wall of the drainage tube, and with its institute
The medicine filled cavity of correspondence position is connected.
Further, the inside of the medicine filled cavity is provided with the packing space for being used for depositing medicine, and the medicine passes through
The form of ultrasonic atomizatio is filled in the packing space inside the medicine filled cavity.
Further, the medicine includes：Mitomycin, liver mycin, heparin are mixed, rapamycin, PLA, polyglycolic acid
One kind or any several combinations in copolymer, makrolon, phosphocholine, fluoropolymer.
Further, the cross sectional shape of the fluid passage is circular, ellipse or rectangle.
Further, the cross sectional shape of the medicine filled cavity is flat.
Further, the quantity of the medicine filled cavity is five.
Further, the drainage tube is made of biocompatible materials.
Further, limit assembly is provided with the outer wall of the drainage tube, the limit assembly is used to draw described in fixation
Relative position of the flow tube in use state.
Further, mark component is provided with the outer wall of the drainage tube, the mark component is used to mark described draw
Relative position of the flow tube in use state.
In order to solve the above technical problems, the present invention also provides a kind of medicine equipment, it includes conveying device, the conveying dress
Put for conveying described conduction type flexible miniature support, it equally includes the drainage tube of multi-cavity, the drainage of the multi-cavity
Pipe is passed through along the path entered from the scleral spur of anterior chamber's eyes in epichoroidal space, wherein, the drainage tube of the multi-cavity is extremely
Include less：One fluid passage, multiple medicine filled cavities and multiple drug releasing pores；The fluid passage is along the drainage tube
Through is set, and it has inflow entrance and flow export；Multiple medicine filled cavities are arranged at the periphery of the fluid passage,
And set respectively along the circumferential insertion of the drainage tube；Multiple drug releasing pores are opened in the outer wall of the drainage tube
On, and be connected with the medicine filled cavity of its corresponding position.
Using above-mentioned technical proposal, the present invention has the advantages that：
The present invention provides a kind of conduction type flexible miniature support, and an otch is formed on the cornea of eyes, and this is miniature
Support is fixed in the anterior chamber of eyes by the otch.The miniature support enters on choroid along from the scleral spur of anterior chamber's eyes
The path of intracavitary is passed through, and the fluid passage of miniature support is by guiding the aqueous humor inflow epichoroidal space of anterior chamber to reach reduction eye
The purpose of internal pressure.Meanwhile, medicine filled cavity can effectively, enduringly in fixed position be discharged medicine, greatly be reduced
Fixed position propagation and the situation of inflammation.
Brief description of the drawings
, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical scheme of the prior art
The accompanying drawing used required in embodiment or description of the prior art is briefly described, it should be apparent that, in describing below
Accompanying drawing is some embodiments of the present invention, for those of ordinary skill in the art, before creative work is not paid
Put, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 for eyes anterior chamber and back room a part of eyes sectional block diagram；
Fig. 2 is the viewgraph of cross-section of eyes；
Fig. 3 is the structural representation of conduction type flexible miniature support provided in an embodiment of the present invention；
Fig. 4 is the side schematic view of conduction type flexible miniature support provided in an embodiment of the present invention.
Reference：
1- fluid passages；2- medicine filled cavities；3- drug releasing pores.
Embodiment
Technical scheme is clearly and completely described below in conjunction with accompanying drawing, it is clear that described implementation
Example is a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill
The every other embodiment that personnel are obtained under the premise of creative work is not made, belongs to the scope of protection of the invention.
In the description of the invention, it is necessary to explanation, term " " center ", " on ", " under ", "left", "right", " vertical ",
The orientation or position relationship of the instruction such as " level ", " interior ", " outer " be based on orientation shown in the drawings or position relationship, merely to
Be easy to the description present invention and simplify description, rather than indicate or imply signified device or element must have specific orientation,
With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.In addition, term " first ", " second ",
" the 3rd " is only used for describing purpose, and it is not intended that indicating or implying relative importance.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or be integrally connected；Can
To be mechanical connection or electrical connection；Can be joined directly together, can also be indirectly connected to by intermediary, Ke Yishi
The connection of two element internals.For the ordinary skill in the art, above-mentioned term can be understood as the case may be
Concrete meaning in the present invention.
The embodiment of the present invention is described in detail below in conjunction with accompanying drawing.It should be appreciated that this place is retouched
The embodiment stated is merely to illustrate and explain the present invention, and is not intended to limit the invention.
Embodiment one
Understand for convenience, the construction of anterior chamber and back room between the present embodiment is introduced first to eyes are simply retouched
State.With reference to shown in Fig. 2, eyes are usually spherical, and are covered by sclera S outside it.Retina R is covered with later half in eyes
In part.Retina recording light, and transmit a signal to brain via optic nerve.Eyes are largely full of and propped up by vitreum
Support, vitreum is a kind of limpid, g., jelly-like material.
Elastic crystalline lens L is located near ocular region.Crystalline lens L provides the adjustment of focus, and is suspended in from eyelash
In shape body CB pouch, ciliary body CB includes the muscle for changing crystalline lens focal length.Split by iris I in space before crystalline lens L
Into two parts, iris controls lenticular aperture and reaches the light quantity of retina.Pupil is a hole for being located at iris I centers,
Light passes through via pupil.Space between iris I and crystalline lens L is back room PC.Before space between iris I and cornea is
Room AC.Anterior chamber and back room are full of the limpid fluid for being referred to as aqueous humor.
Ciliary body CB constantly forms aqueous humor by the secretion from blood vessel in back room PC.Aqueous humor in crystalline lens L and
Anterior chamber is flowed into around iris I, and eyes are left by trabecular network, trabecular network is a kind of angle positioned at iris I and wall of eyeball
The sieve texture of (angle is also referred to as room angle).Some aqueous humors are managed by girder net filtration into SchlemmShi, SchlemmShi
Pipe is the passage aisle that drainage enters eyes vein.Smaller ones are passing through ciliary body, and eventually pass through sclera (sclera road
Line) venous circulation is added again afterwards.
As shown in Figure 3, Figure 4, the conduction type flexible miniature support that the present embodiment one is provided, it includes the drainage of multi-cavity
Pipe, the drainage tube of the multi-cavity is passed through along the path entered from the scleral spur of anterior chamber's eyes in epichoroidal space, wherein, institute
Stating the drainage tube of multi-cavity at least includes：
One fluid passage 1, through of the fluid passage 1 along the drainage tube is set, its have inflow entrance and
Flow export, the fluid passage 1 is by guiding the aqueous humor inflow epichoroidal space of anterior chamber to reach the purpose of reduction intraocular pressure.
Multiple medicine filled cavities 2, multiple medicine filled cavities 2 are arranged at the periphery of the fluid passage 1, and edge respectively
The circumferential insertion of the drainage tube is set, and medicine filled cavity 2 can effectively, enduringly in fixed position be discharged medicine,
It is greatly reduced fixed position propagation and the situation of inflammation；
Multiple drug releasing pores 3, multiple drug releasing pores 3 are opened on the outer wall of the drainage tube, and and its
The medicine filled cavity 2 of corresponding position is connected.
It can be seen that, a kind of drainage tube of multi-cavity of the present embodiment, central hollow allows aqueous humor to pass through, porous and can guarantee that material
Material it is sufficiently ductile, can keep aqueous humor drainage function indeformable for a long time, medicine filled cavity 2 can continue, stable release
Put medicine and reduce the probability that lesion occurs for support fixed position.
The conduction type flexible miniature support, the filling for being used to deposit medicine is provided with the inside of the medicine filled cavity 2 empty
Between, the medicine is filled in the packing space inside the medicine filled cavity 2 by the form of ultrasonic atomizatio.
Specifically, the medicine includes：Mitomycin, liver mycin, heparin are mixed, rapamycin, PLA, polyglycolic acid are common
One kind or any several combinations in polymers, makrolon, phosphocholine, fluoropolymer.
For the concrete structure and size of conduction type flexible miniature support, it can be adjusted flexibly according to actual conditions.
Illustrated below with wherein several preferred examples.
Preferably, the cross sectional shape of the fluid passage 1 is circular, ellipse or rectangle.Fluid in the present embodiment
The cross sectional shape of path 1 is circle.
Preferably, the cross sectional shape of the medicine filled cavity 2 is flat.For example：It is flat sharp oval that it is shaped as two
Shape, certain other shapes can also, will not enumerate herein.
Specifically, the quantity of the medicine filled cavity 2 is five, and five medicine filled cavities 2 are evenly distributed in the stream
The surrounding of body path 1.
In the present embodiment, the drainage tube is made of biocompatible materials.
For example：The drainage tube can use polyimides, ceramics, the organic silicon rubber or stainless of good biocompatibility
Steel or Nitinol etc. biocompatible materials.
Certainly, the drainage tube can also use other materials or material, for example：Other suitable polymer, metal, gold
Belong to alloy, or their various combinations.Other rapidoprints or material include silicones, PTFE, various fluoropolymers,
FEP, the FEP of the laminated node into ePTFE, silver coating (such as via CVD techniques), gold, prolene/polyolefin,
Polyethylene (methyl methacrylate) (PMMA), acrylic resin, polyethylene terephthalate (PET), polyethylene (PE),
PLLA and parylene etc..
Further, limit assembly is provided with the outer wall of the drainage tube, the limit assembly is used to draw described in fixation
Relative position of the flow tube in use state.Limit assembly can be excrescence, wing, tusk or skewer, and they are intervened
Human body, correct position is maintained at by drainage tube.
Further, mark component is provided with the outer wall of the drainage tube, the mark component is used to mark described draw
Relative position of the flow tube in use state.The drainage tube can be with one or more visual, profile scanning, echo
Or radiopaque mark component, mark component can be by being transferred to its applicable mark by above mentioned any device
Knowledge system helps to position.
Embodiment two
The present embodiment two provides a kind of medicine equipment, and it includes conveying device, and the conveying device is used to convey embodiment
Conduction type flexible miniature support described in one.
Specifically, the conduction type flexible miniature support includes the drainage tube of multi-cavity, the drainage tube of the multi-cavity along
The path entered from the scleral spur of anterior chamber's eyes in epichoroidal space is passed through, wherein, the drainage tube of the multi-cavity at least includes：
One fluid passage 1, through of the fluid passage 1 along the drainage tube is set, its have inflow entrance and
Flow export, the fluid passage 1 is by guiding the aqueous humor inflow epichoroidal space of anterior chamber to reach the purpose of reduction intraocular pressure.
Multiple medicine filled cavities 2, multiple medicine filled cavities 2 are arranged at the periphery of the fluid passage 1, and edge respectively
The circumferential insertion of the drainage tube is set, and medicine filled cavity 2 can effectively, enduringly in fixed position be discharged medicine,
It is greatly reduced fixed position propagation and the situation of inflammation；
Multiple drug releasing pores 3, multiple drug releasing pores 3 are opened on the outer wall of the drainage tube, and and its
The medicine filled cavity 2 of corresponding position is connected.
As for other features, have described in detail above, here is omitted.
Finally it should be noted that：Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations；To the greatest extent
The present invention is described in detail with reference to foregoing embodiments for pipe, it will be understood by those within the art that：Its according to
The technical scheme described in foregoing embodiments can so be modified, or which part or all technical characteristic are entered
Row equivalent substitution；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology
The scope of scheme.
Claims (10)
1. a kind of conduction type flexible miniature support, it is characterised in that the drainage tube including multi-cavity, the drainage tube of the multi-cavity
Passed through along the path entered from the scleral spur of anterior chamber's eyes in epichoroidal space, wherein, the drainage tube of the multi-cavity is at least
Including：
One fluid passage, through of the fluid passage along the drainage tube is set, and it has inflow entrance and flow export；
Multiple medicine filled cavities, multiple medicine filled cavities are arranged at the periphery of the fluid passage, and draw respectively along described
The circumferential insertion of flow tube is set；
Multiple drug releasing pores, multiple drug releasing pores are opened on the outer wall of the drainage tube, and with corresponding to it
The medicine filled cavity of position is connected.
2. conduction type flexible miniature support according to claim 1, it is characterised in that the inside of the medicine filled cavity is set
There is the packing space for depositing medicine, the medicine is filled in inside the medicine filled cavity by the form of ultrasonic atomizatio
In packing space.
3. conduction type flexible miniature support according to claim 2, it is characterised in that the medicine includes：Mitomycin,
Liver mycin, heparin are mixed, in rapamycin, PLA, co-glycolic acid, makrolon, phosphocholine, fluoropolymer
A kind of or any several combinations.
4. conduction type flexible miniature support according to claim 1, it is characterised in that the cross sectional shape of the fluid passage
For circular, ellipse or rectangle.
5. conduction type flexible miniature support according to claim 1, it is characterised in that the section shape of the medicine filled cavity
Shape is flat.
6. conduction type flexible miniature support according to claim 5, it is characterised in that the quantity of the medicine filled cavity is
Five.
7. conduction type flexible miniature support according to claim 1, it is characterised in that the drainage tube uses bio-compatible
Property material is made.
8. conduction type flexible miniature support according to claim 1, it is characterised in that set on the outer wall of the drainage tube
Limited location component, the limit assembly is used to fix relative position of the drainage tube in use state.
9. conduction type flexible miniature support according to claim 1, it is characterised in that set on the outer wall of the drainage tube
There is mark component, the mark component is used to mark the drainage tube in the relative position of use state.
10. a kind of medicine equipment, it is characterised in that including conveying device, the conveying device is used to convey such as claim 1-9
Any one of conduction type flexible miniature support.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710084146.2A CN106963543A (en) | 2017-02-16 | 2017-02-16 | Conduction type flexible miniature support and medicine equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710084146.2A CN106963543A (en) | 2017-02-16 | 2017-02-16 | Conduction type flexible miniature support and medicine equipment |
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| CN106963543A true CN106963543A (en) | 2017-07-21 |
Family
ID=59334796
Family Applications (1)
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| CN201710084146.2A Pending CN106963543A (en) | 2017-02-16 | 2017-02-16 | Conduction type flexible miniature support and medicine equipment |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524096A (en) * | 2018-06-28 | 2018-09-14 | 吴莺 | Aqueous humor drainage device is fixed in a kind of sclera |
| CN108743014A (en) * | 2018-06-11 | 2018-11-06 | 温州医科大学 | For lasting sexual balance across sieve plate pressure difference across the sieve plate pressure difference method of across sieve plate pressure balance maintainer and implanted device and balance |
| CN109431678A (en) * | 2018-12-17 | 2019-03-08 | 中国医学科学院北京协和医院 | Through sclerocorneal drug delivery system |
| CN116322583A (en) * | 2020-07-22 | 2023-06-23 | 国立大学医院（新加坡）私人有限公司 | Eye drainage implant |
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