CN106955176A - Stomach beaded support - Google Patents

Stomach beaded support Download PDF

Info

Publication number
CN106955176A
CN106955176A CN201710182439.4A CN201710182439A CN106955176A CN 106955176 A CN106955176 A CN 106955176A CN 201710182439 A CN201710182439 A CN 201710182439A CN 106955176 A CN106955176 A CN 106955176A
Authority
CN
China
Prior art keywords
stomach
bone
beaded support
support
circle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710182439.4A
Other languages
Chinese (zh)
Inventor
王东
苏晓清
文剑波
何建中
叶君明
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CN106955176A publication Critical patent/CN106955176A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/003Implantable devices or invasive measures inflatable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/0036Intragastrical devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0089Instruments for placement or removal

Landscapes

  • Health & Medical Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Nursing (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)

Abstract

The invention discloses stomach beaded support, it is made up of metal alloy wires, and stomach beaded support includes upper circle(1), lower circle(4), bone warp(2)With bone parallel(3), upper circle and lower circle be oppositely arranged, and bone warp is connected into arc-shaped interval setting, bone warp one end with upper circle, and the other end is connected with lower circle;The bone parallel interweaves in latticed with bone warp equi-spaced apart in the shape of a spiral;The stomach beaded support release conditions are netted spherical, and contraction state is cylinder tube shape.Spherical stomach support smooth in appearance and rich soft and elastic characteristic, can passively it be wriggled with peristole in gastral cavity, plus the smooth interior environment of moistening of gastric secretion, beaded support position movement in stomach is changeable, therefore will not mutually be embedded in stomach body cavity, also will not be by gastric mucosa " embedding ", beaded support is convenient under gastroscope auxiliary to be taken out at any time, and it is reusable, it can effectively prevent that slimmer from using into middle generation adverse reaction and fat bounce-back.

Description

Stomach beaded support
Technical field
It is used to reduce stomach volume the present invention relates to technical field of medical instruments, more particularly to one kind, subtracts so as to reach and go on a diet The stomach beaded support of fertilizer efficiency fruit.
Background technology
Stomach is the organ that human body accommodates food, the appetite and food-intake of the direct decider of volume size of stomach.Food-intake is more, It is fat material base to cause " intake is more than consumption ".As people's living standard is improved and lifestyle change, overweight people Growing day by day, fat related metabolic diseases also constantly rise.Generally, the food-intake of overweight people is all larger, that is to say, that Gastral cavity volume is relatively large.It is the go on a diet effective means and developing direction of fat-reducing to reduce gastral cavity volume with non-traumatic manner.
People lose weight in life, moved generally by increase, the method such as keep a diet to realize.But, if motion Do not reach a certain amount of, time can not continue then fat-reducing effect it is undesirable or bounce-back;Although going on a diet to lose weight, to feeding urges Resisting needs very big willpower, and ordinary person is difficult to adhere to, add it is improper for a long time go on a diet, people is known from experience because lacking necessary nutritional factors Bring energy and physically-draining, influence work and quality of life.Medical means fat-reducing it is main by reducing stomach volume to control food It is intended to, food-intake is declined the effect so as to reach fat-reducing and lose weight.Reducing stomach volume at present mainly has following two modes: One is surgical operation volume reduction, including gastric bypass operation, stomach sleeve resection etc., its stomach volume reduction and weight loss effect affirmative, but hand The unfavorable factors such as art wound is big, irreversible, risk and expense height, overweight people is difficult to receive;Two be non-surgery operation volume reduction, bag Include stomach band art.For the above mentioned problem in the presence of fat-reducing, recent people in gastral cavity by placing water polo(U.S. FDA 2015 approval Registering products)To reduce stomach volume, feeding urges are reduced, so as to reduce the purpose that food-intake reaches fat-reducing.Although This fat-reducing effect for placing water polo capsule under one's belt preferably, but there is problems in actual use:1. stomach water polo capsule is noted Weight is big after 500 700 milliliters of water, and insufferable abdominal pain and distension, vomiting etc. occurs no in the people for being placed on after gastral cavity about 20% Good reaction, slimmer is forced to take out water polo termination treatment in advance;2. stomach water polo capsule easily forms gastric erosion to gastric mucosa oppression With the severe complication such as ulcer;3. sacculus uses macromolecular material(Polyurethane, silicon are as glue etc.)It is made, is easily collapsed under sour environment Solution and breakage, therefore put in vivo by time restriction(<6 months);4. current stomach sacculus need to be from external import, price is high, general fertilizer Fat person is difficult to bear, and is unfavorable for popularizing.
The content of the invention
For above-mentioned in the prior art using the problems of stomach volume reduction equipment, the invention provides one kind is flexible The stomach beaded support that memory function, human compatibility are good, be easy to discharge and reclaim, tolerance strong and can reverse.
The technical problem to be solved in the present invention is adopted the technical scheme that:The stomach beaded support is by metal alloy wires system Into it includes upper circle, lower circle, bone warp and bone parallel, and the upper and lower circle is oppositely arranged, and bone warp is between arc-shaped Every setting, bone warp one end is connected with upper circle, the other end is connected with lower circle;The bone parallel is in the shape of a spiral with bone warp etc. It is woven into away from interleaved latticed, the stomach beaded support release conditions is netted spherical, and contraction state is tiny cylindrical tube Shape;The metal alloy wires are 0.1-0.3 millimeters of Nickel titanium alloy wires.
Current physianthropy is mainly used for releasing focus using various human bodies " support "(Such as blood vessel, oesophagus, stomach and intestine, courage Pipe etc.)" obstruction " problem, to realize that support is placed in obstruction local " leading to again ".Therefore all support basic configurations are all in " pipe Shape ", and be generally permanent put.The present invention is broken traditions " tubulose " support concept, and " support " is designed to have memory function " spherical ", entitled " beaded support ", a kind of equipment special for being used to lose weight in this, as medical institutions." beaded support " It is the spherical network structure that tool memory function is woven into using single micro- footpath Nickel titanium alloy wires, it can be in contraction state(In tiny Cylindrical tube shape)It is accommodated in special pusher, enters gastral cavity under gastroscope auxiliary, the then elasticity release in stomach, its is enough And impartial outer malleability expansive force(Tension force)Coat of the stomach is balancedly supported with good compliance, gastral cavity is in relative expanded state And stimulate coat of the stomach " baroreceptor ", then by the way that coat of the stomach is incoming, efferent nerve Information Conduction, human body thus produce feeling of repletion and from Hair reduces food-intake.Beaded support is indwelling 3-6 months in gastral cavity, and this period overweight people is constantly in spontaneous low food-intake shape State, reaches after fat-reducing weight loss effect, can clamp support under gastroscope auxiliary by dentation biopsy forceps or foreign body forcepses and as needed Force(Up or down circle)And pull backward, using the soft contractibility feature of support, comply with digestive tract cavity(Stomach, esophagus)It is squeezed into Elongate strip is tubular to be exited in vitro in the lump with gastroscope, directly takes out the beaded support.
" beaded support " strong mechanical property, smooth in appearance and rich in soft and elastic characteristic, can in gastral cavity with Peristole and passively wriggle, add the smooth interior environment of moistening of gastric secretion, beaded support position movement in stomach is changeable, therefore Will not mutually it be embedded in stomach body cavity, also will not be by gastric mucosa " embedding ", therefore beaded support is convenient under gastroscope auxiliary takes out at any time, And it is reusable, it can effectively prevent that slimmer from using into middle generation adverse reaction and fat bounce-back.
Beneficial effects of the present invention, compared to existing technologies:
1 and surgical operation(Such as gastric bypass operation, stomach sleeve dress resection)Compared to human body it is noninvasive, can reverse, risk system The lower advantage of the small, expense of number, easily receives for people, can not only reduce the pain of slimmer, and can obtain good fat-reducing Effect;
2nd, compared with stomach sacculus, beaded support weight can be ignored substantially, to the agravic compressing of coat of the stomach and bearing down, using comfortable Degree increase, therefore the compliance of slimmer is good:Meanwhile, material therefor is safer, resistance to acid attack, will not be damaged, to human body side effect Small, risk incidence is low;The complication such as gastric erosion, gastric ulcer, gastrorrhagia caused by long-term local compression can be avoided, and is laid With it is convenient to remove, be its advantage;
3. present invention innovation is brand new ideas, with material safety, mature production technology, weight reducing treatments good reversibility.This is spherical netted Gastric wall tension receptor is stimulated after support release, stimulation after taking out is reclaimed and disappears, body recovery original state does not constitute permanent damage Wound, therefore repeatable interruption is used;
4. beaded support geometry more meets ergonomics, compatibility is more preferable;Feel depending on overweight people and actual effect, it is optional Different model beaded support is selected, support number is converted, can further adapt to different overweight peoples.
Brief description of the drawings
Fig. 1 is the overlooking the structure diagram after present invention release,
Fig. 2 is the use state schematic diagram after the present invention discharges in stomach,
Fig. 3 is the beaded support pusher cross section structure diagram of the present invention,
View when Fig. 4 is the preparation recovery of the present invention,
Fig. 5 is the state diagram that the present invention is withdrawn,
Fig. 6 is the view after the present invention is withdrawn.
In figure, 1, upper circle 2, bone warp 3, bone parallel 4, lower circle 5, duodenum 6, gastral cavity 7, Esophagus 8, push-and-pull portion 9, preceding adapter sleeve 10, guide collar 11, rear adapter sleeve 12, overcoat 13, seal wire 14, fixation Press from both sides 15a, inner sleeve leading portion 15b, inner sleeve back segment 16, straight pipe 17, biopsy forceps 18, gastroscope.
Embodiment:
In order that those skilled in the art more fully understand technical scheme, combining specific implementation below according to accompanying drawing lifts Example is described in further detail the present invention.
According to known to background technology, " beaded support " must technically possess following key element:1. support is harmless;2. Put and be retractable into soft tubulose when reclaiming and be easy to direct oral cavity-oesophagus into and out of human body, can instantaneous elasticity release in gastral cavity Into the spheroidal of design;3. having the export-oriented tension force of certain flexibility and favorable elasticity after release, it can move, not occur with peristole " mutually embedding " and tissue " embedding ";4. it is easy to support to put and take out under gastroscope auxiliary.
In Fig. 1,2, the stomach beaded support is made up of Nickel titanium alloy wires(It is of course also possible to be other elastic alloy materials Material), support network structure spherical in shape after being discharged in stomach, including upper circle 1, lower circle 4, bone warp 2 and bone parallel 3;It is described Upper and lower circle is oppositely arranged, and bone warp is connected into arc-shaped interval setting, bone warp one end with upper circle, the other end and lower circle Circle is connected;The bone parallel is in the shape of a spiral with bone warp equi-spaced apart weaving in latticed, the stomach beaded support release State is netted spherical(Or almost spherical or oval spherical), contraction state is cylinder tube shape(Or reducing tubulose).
In figure 3, described " beaded support pusher " belongs to auxiliary implement, and it includes push-and-pull portion 8, overcoat 12, inner sleeve (It is divided into the inner sleeve leading portion 15a being connected and inner sleeve back segment 15b, inner sleeve leading portion is transparent visual portion), guide collar 10, straight pipe 16th, preceding adapter sleeve 9, rear adapter sleeve 11, seal wire 13(Seal wire is fixed on the front end of inner sleeve leading portion), overcoat front end geometrical clamp 14, Its seal wire front end passes through the upper and lower circle of beaded support(Play guiding and supporting role), support pull backward simultaneously is pushed forward The beaded support being compressed in pusher overcoat then can be departed to release after geometrical clamp 14 by seal wire as opening " umbrella " arrives stomach In chamber 6(Gastral cavity connects esophagus 7 and duodenum 5), instant recovery ball shape after support release;Recovery state such as Fig. 4-Fig. 6 It is shown(The state change contrast of the support of release process and removal process), a. is through the biopsy duct of gastroscope 18 stretching biopsy forceps 17 grade annexes;B. circle on beaded support is clamped to pull back;C. made using coat of the stomach and the own tension of esophagus 7 and stent flexibility elastic force Support bounces back in adaptability;D. support is taken out through esophagus, oral cavity with gastroscope.
" beaded support " is woven into collapsible Hui Na into after thin tube-like and release using fine single Nickel titanium alloy wires Can instantaneous recovery spheroidal network structure, overlay film or not two kinds of cantilever types of overlay film can be processed into respectively;The bone parallel and Bone warp interweaves with forming the spacing rate of grid of network structure for 0.3~0.5cm square, and beaded support diameter is of different sizes by model For 6~10cm;Each reserved symmetrical upper and lower circle of spheroid bone parallel upper and lower end, overall to link, upper and lower circle sets pore size That only can be advisable by seal wire, facilitate support to be slided along seal wire as silk guide passage, discharge and reclaim beneficial to support.Accessory is main Including the special pusher of beaded support and gastroscope related accessories.
The use procedure declaration of the present invention:
1st, doctor is according to the fat situation and other human body essential characteristics of overweight people such as body surface area, body mass index, average feed Amount etc., contraindication is excluded through gastrocopy, is chosen suitable big ting model and the beaded support in interior receipts state, is matched somebody with somebody using special Beaded support, individually or under gastroscope auxiliary is placed in stomach body cavity and then discharges, exit and match somebody with somebody by part " beaded support pusher " Part, beaded support is retained in gastral cavity;Judge according to different overweight people's situations by doctor, select the spherical branch of model of different sizes Frame, it is conventional to place 1-2;
2nd, the 7-10 days interior close observation slimmers after Stent Implantation, tight for occurring abdominal distension, stomachache, vomiting etc. within the observation period The slimmer of weight complication, can suitably using spasmolysis, antiemetic and proton pump inhibitor with to alleviate;
3rd, beaded support is retained in 3~6 months or longer time in gastral cavity, then visual sense is by appetite change, body mass index, fat-reducing The concrete conditions such as effect, beaded support is taken out under the annex such as gastroscope and biopsy forceps auxiliary.Beaded support can repeat to put.
Embodiment of above is merely illustrative of the technical solution of the present invention and unrestricted, although with reference to specific embodiment to this Invention is described in detail, it will be understood by those within the art that, technical scheme can be repaiied Change or equivalent, without departing from the spirit and scope of technical solution of the present invention, it all should cover will in right of the invention In the scope for asking protection.

Claims (2)

1. stomach beaded support, it is characterised in that:It is made up of metal alloy wires, and the stomach beaded support includes upper circle(1), under Circle(4), bone warp(2)With bone parallel(3), the upper circle and lower circle be oppositely arranged, and bone warp is set into arc-shaped interval Put, bone warp one end is connected with upper circle, the other end is connected with lower circle;The bone parallel in the shape of a spiral with bone warp it is equidistant between Every weaving into latticed;The stomach beaded support release conditions are netted spherical, and contraction state is cylinder tube shape.
2. stomach beaded support according to claim 1, it is characterised in that:The metal alloy wires are 0.1-0.3 millimeters of Nickel Titanium alloy wire.
CN201710182439.4A 2016-04-30 2017-03-24 Stomach beaded support Pending CN106955176A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610277006.2A CN105769404A (en) 2016-04-30 2016-04-30 Volume-reducing stomach stent
CN2016102770062 2016-04-30

Publications (1)

Publication Number Publication Date
CN106955176A true CN106955176A (en) 2017-07-18

Family

ID=56399968

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201610277006.2A Pending CN105769404A (en) 2016-04-30 2016-04-30 Volume-reducing stomach stent
CN201710182439.4A Pending CN106955176A (en) 2016-04-30 2017-03-24 Stomach beaded support

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201610277006.2A Pending CN105769404A (en) 2016-04-30 2016-04-30 Volume-reducing stomach stent

Country Status (1)

Country Link
CN (2) CN105769404A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110420005A (en) * 2019-08-09 2019-11-08 上海市第一人民医院 It is expansible, with telescopic arm, the miniature gastroscope robot that can be colonized

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110974504A (en) * 2019-12-18 2020-04-10 广州新诚生物科技有限公司 Covered stent, preparation method thereof and weight-reducing stent system comprising covered stent
CN113057777B (en) * 2021-05-06 2022-03-25 哈尔滨医科大学 Weight-losing device with intragastric support
CN114129779A (en) * 2021-12-06 2022-03-04 杭州糖吉医疗科技有限公司 Ultrathin balloon for stomach implantation, preparation method thereof and balloon with weight-losing effect
CN114159199A (en) * 2021-12-24 2022-03-11 山东百多安医疗器械股份有限公司 Weight-losing balloon with through hole and preparation method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2571401Y (en) * 2002-08-20 2003-09-10 胡晓民 Crossless support made of nickel-titanium memory alloy for medical use
CN1575155A (en) * 2001-08-27 2005-02-02 辛尼科有限责任公司 Satiation devices and methods
CN2865572Y (en) * 2006-01-04 2007-02-07 高运乾 Swallowing gastric capacity-reducing sack
CN2930654Y (en) * 2006-07-18 2007-08-08 肖英龙 Soft capsule inserted into stomach
CN101310692A (en) * 2007-05-21 2008-11-26 上海交通大学医学院附属新华医院 Weight reduction bracket in stomach
WO2014026215A1 (en) * 2012-08-17 2014-02-20 Simple Medical Innovations Pty Ltd Intragastric balloon

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1575155A (en) * 2001-08-27 2005-02-02 辛尼科有限责任公司 Satiation devices and methods
CN2571401Y (en) * 2002-08-20 2003-09-10 胡晓民 Crossless support made of nickel-titanium memory alloy for medical use
CN2865572Y (en) * 2006-01-04 2007-02-07 高运乾 Swallowing gastric capacity-reducing sack
CN2930654Y (en) * 2006-07-18 2007-08-08 肖英龙 Soft capsule inserted into stomach
CN101310692A (en) * 2007-05-21 2008-11-26 上海交通大学医学院附属新华医院 Weight reduction bracket in stomach
WO2014026215A1 (en) * 2012-08-17 2014-02-20 Simple Medical Innovations Pty Ltd Intragastric balloon

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110420005A (en) * 2019-08-09 2019-11-08 上海市第一人民医院 It is expansible, with telescopic arm, the miniature gastroscope robot that can be colonized
CN110420005B (en) * 2019-08-09 2021-09-28 上海市第一人民医院 Expandable miniature gastroscope robot with telescopic arm and field planting function

Also Published As

Publication number Publication date
CN105769404A (en) 2016-07-20

Similar Documents

Publication Publication Date Title
CN106955176A (en) Stomach beaded support
CN201879873U (en) Recyclable esophageal stent of nickel titanium memory alloy full-membrane exceeding opening
CN108938163B (en) Gastric inducer and method of releasing same
CN103479454B (en) Stomach food diverter
EP1366732A3 (en) Stent delivery system having a fixed guide wire
CN206995365U (en) Duodenal stent and duodenal stent device for posting
CN102824239A (en) Small intestine sleeve
CN201920790U (en) Sleeve for isolating small intestine from food
CN108635092B (en) Stomach divertor and alimentary canal support thereof
CN107485481A (en) A kind of penis fixed support
CN101243999A (en) Aorta bracket with valve of recoverable and adjustable position
CN110974504A (en) Covered stent, preparation method thereof and weight-reducing stent system comprising covered stent
CN204562475U (en) A kind of bottle shape stent in esophagus being applicable to treatment high position of esophageal stenosis
CN204910437U (en) Small intestine biconjugate is than radiography pipe
CN212997509U (en) Nose intestines tube
WO2019196380A1 (en) Gastric diverter and digestive tract support and release method thereof
CN203169227U (en) Inner tectorial membrane for duodenum
CN208864588U (en) Stomach air deflector and its alimentary stent
CN209360641U (en) A kind of painless gastroscope seaming
CN211382823U (en) Auxiliary device for placing naso-intestinal tube into patient with tracheal intubation
CN206924134U (en) Colon support and colon support inserting device
CN215192617U (en) Disposable stent fixing device for transgastroscope intragastric stent implantation
CN201168081Y (en) Recoverable aorta stent with valve with adjustable position
CN212755768U (en) Anti-displacement metal stent for cholangiojejunostomy
CN219126984U (en) Wound nursing ostomy abdominal belt

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20170718

RJ01 Rejection of invention patent application after publication