CN106943218B - Implantation material transportation system - Google Patents

Implantation material transportation system Download PDF

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Publication number
CN106943218B
CN106943218B CN201710175609.6A CN201710175609A CN106943218B CN 106943218 B CN106943218 B CN 106943218B CN 201710175609 A CN201710175609 A CN 201710175609A CN 106943218 B CN106943218 B CN 106943218B
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China
Prior art keywords
implantation material
transportation system
connecting rod
material transportation
ring
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Active
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CN201710175609.6A
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Chinese (zh)
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CN106943218A (en
Inventor
白厄尔
迪恩·谢弗
杰罗姆·克洛伊
丹·丁
路易斯·卡德纳斯
冯骋骋
钱承
保罗·道
乔纳森·波兰斯基
克里斯多夫·弗莱厄蒂
保罗·埃林格
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Shanghai Warbey Medical Technology Co Ltd
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Shanghai Warbey Medical Technology Co Ltd
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Application filed by Shanghai Warbey Medical Technology Co Ltd filed Critical Shanghai Warbey Medical Technology Co Ltd
Priority to CN201911281371.0A priority Critical patent/CN110859693B/en
Priority to CN201911282082.2A priority patent/CN110801259A/en
Priority to CN201911281360.2A priority patent/CN110859692B/en
Priority to CN201911281338.8A priority patent/CN110859691B/en
Publication of CN106943218A publication Critical patent/CN106943218A/en
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Publication of CN106943218B publication Critical patent/CN106943218B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/962Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve
    • A61F2/966Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)

Abstract

The invention discloses a kind of implantation material transportation systems, including the implantation material with mesh mechanism;Releasing mechanism including the connecting rod containing distal portion point, the releasing mechanism are attached to the mesh mechanism of the implantation material;And its construction and layout are the controlling mechanism for manipulating the releasing mechanism and the releasing mechanism being made to be detached from the implantation material.Implantation material transportation system provided by the invention can carry out implantation material quick release in desired implantation position.

Description

Implantation material transportation system
The application is associated with a U.S. Provisional Patent Application, number of patent application 62/368,927, entitled " implantation material Transportation system and method are filed on July 29th, 2016, this application content will be added in full text for the purpose of reference.
Technical field
The present invention relates to a kind of system of the one or more implantation materials for patient of conveying more particularly to it is a kind of can be in the phase The implantation position of prestige carries out the implantation material transportation system and equipment of implantation material quick release.
Background technique
Vascular occlusion equipment, bracket and other implantation materials are used for various medical treatment, including endovascular aneurysm and blood vessel limit The treatment of system.Vascular occluding device generally includes one and is fixed in blood vessel or artery tumor, soft such as blood vessel or cerebral aneurysm Spiral wound spring ring.Bracket may include the fexible bias pressure knot of self expandable or by using expansible air bag plastic deformation Structure.Vascular occluding device, bracket and other implantation materials are usually filled by the conveying based on a percutaneous conduit for introducing patient's body Set it is adjoint, proceed to adjacent to implantation point.The accuracy that one or more implantation materials are placed into desired position is generally difficult to In the mode that implantation material is discharged from delivery conduit.
Thus and other reasons, to the improved system that can be accurately positioned one or more implantation materials in desired implant site System, method and apparatus, which exist, generally to be needed.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of implantation material transportation systems, can be in desired implantation position Carry out the implantation material transportation system and equipment of implantation material quick release.
The one aspect of concept according to the present invention, a kind of implantation material transportation system include the implantation material with mesh mechanism; A kind of releasing mechanism comprising the connecting rod with distal portions, the releasing mechanism are attached to the engagement of the implantation material Mechanism;And a kind of control mechanism, constructing and be laid out in the manipulation releasing mechanism makes the releasing mechanism be detached from the plant Enter object.
It in some embodiments, further include the elongated shaft being arranged at least about a part of the connecting rod, it is described elongated Axis contains proximal end, distal portions and distal end.
In some embodiments, the elongated shaft includes knitted parts.
In some embodiments, the knitted parts include the single line with about 0.0015 inch outer diameter.
In some embodiments, the knitted parts include outer diameter between 0.00125 inch and 0.0015 inch Multi cord.
In some embodiments, the knitted parts it is reserved close to the distal end of the elongated shaft when reduction spacing.
In some embodiments, the elongated shaft, which is constructed and is laid out in, frictionally engages the connecting rod.
In some embodiments, the elongated shaft includes the outer tube for accounting for described axis at least part position.
In some embodiments, the elongated shaft include at least one of wall of the axis be open, it is described extremely The position of a few opening for providing access during manufacture, to be inserted into the mesh mechanism at least one in the axis Point.
In some embodiments, at least part of the elongated shaft is tapered major diameter.
In some embodiments, the elongated shaft includes the proximal part of first external diameter, the axis distal portions Second external diameter including being less than the first external diameter, and from first external diameter to the middle part of the various outer diameter of second external diameter transition Point.
In some embodiments, the first external diameter is about 0.014 inch, and the second external diameter is about 0.011 inch.
It in some embodiments, further include the amplifier section on the connecting rod distal portions.
In some embodiments, the implantation material is resilient compression shape.
In some embodiments, the implantation material includes at least one filiform.
In some embodiments, the implantation material includes at least two filiforms.
In some embodiments, at least one filiform includes elastic strands.
In some embodiments, at least one filiform is in compressive state with by the translatable of the implantation material Part is maintained in the hollow space of the implantation material.
In some embodiments, the implantation material includes at least one spring ring.
In some embodiments, the implantation material includes the first spring ring and second spring circle.
In some embodiments, first spring ring and the second spring circle include different diameters.
In some embodiments, first spring ring and the second spring circle are wound in same direction.
In some embodiments, first spring ring and the second spring circle are wound in different directions.
In some embodiments, first spring ring is soldered to the second spring circle.
In some embodiments, the implantation material includes rounded tip ball portion on its distal end.
In some embodiments, the mesh mechanism includes the enlarged engaged with the releasing mechanism release property.
In some embodiments, the mesh mechanism includes the filiform with ring, the ring and the releasing mechanism Releasably engage.
In some embodiments, the ring is attached to the second filiform, and second filiform is in elastic compression The ring to be drawn the hollow space to the implantation material by state.
In some embodiments, the ring includes Nitinol.
In some embodiments, the diameter of the ring is about 0.001 inch.
It in some embodiments, further include visual marker object.
In some embodiments, the mesh mechanism includes the filiform with ring, and the releasing mechanism includes pin, institute It states filiform and winds the pin, and the connecting rod captures the ring the connecting rod and the pin, institute across the ring The retraction for stating connecting rod discharges the implantation material.
It in some embodiments, further include around at least part of axis of the connecting rod and including having opening Wall, the mesh mechanism include the filiform with ring, and the releasing mechanism includes the protruding portion of the distal end from the connecting rod Position, the protruding parts pass through the ring, capture the ring, and the retraction of the connecting rod discharges the implantation material.
It in some embodiments, further include around at least part of axis of the connecting rod and including being opened with slope shape The wall of mouth, the mesh mechanism includes the filiform with ring, and the releasing mechanism includes the hook of the distal end from the connecting rod Portion, the outside for surrounding the axis simultaneously enters the slope shape opening, and the hook portion captures the ring, the connecting rod Advance be detached from the hook portion from the ring, to discharge the implantation material.
In some embodiments, the mesh mechanism includes the filiform with ring, and the releasing mechanism includes sleeve, It is described to be wound around the sleeve, and the connecting rod passes through the lantern ring and enters the sleeve, captures the ring, the company The retraction of bar discharges the implantation material.
In some embodiments, further include around at least part of axis of the connecting rod and including inner wall, it is described to nibble Conjunction mechanism includes the filiform with ring, and the releasing mechanism includes the ramped shaped protrusion to extend out from the axis inner wall With in the wedge-shaped amplifier section of the connecting rod distal portions, the ring winds the slope and the wedge-shaped amplifier section capture The ring, and the retraction of the connecting rod discharges the implantation material.
In some embodiments, the mesh mechanism includes port, and the releasing mechanism includes amplifier section, the company Bar makes the engagement of the amplifier section Yu the port frictional property, captures the port, and the retraction of the connecting rod discharges institute State implantation material.
It in some embodiments, further include around at least part of axis of the connecting rod, the amplifier section is tied in On the axis.
It in some embodiments, further include around at least part of axis of the connecting rod, the mesh mechanism includes silk Shape object, the filiform include anchor on its distal end, anchor fexible bias pressure under compact condition, the releasing mechanism packet The nozzle shape distal portions of the axis are included, the distal end of the connecting rod expands the anchor, captured the nozzle shape in the axis In distal portions, and the retraction of the connecting rod allows the anchor to shrink, and discharges the implantation material.
It in some embodiments, further include around at least part of axis of the connecting rod, the mesh mechanism includes containing There is a filiform of amplifier section, the releasing mechanism includes the grasping mechanism of fexible bias pressure in the expanded state and in the axis Recess portion, the retraction of the connecting rod keeps the grasping mechanism mobile towards the recess portion, expands to the recess portion and described in being detached from Amplifier section discharges the implantation material.
It in some embodiments, further include around at least part of axis of the connecting rod, the mesh mechanism is included in Fexible bias pressure is attached to the filiform of pipe under compact condition, and the relieving mechanism includes amplifier section, the amplifier section positioning In the pipe, makes the tube swelling with the axis that is frictionally engaged, capture the pipe, the retraction of the connecting rod makes the enlarging section The pipe is separated, allows the caliber to the axis is retracted and disengage from, discharges the implantation material.
In some embodiments, the pipe includes at least one protruding parts, and the protruding parts are configured to when described Pipe engages the axis when being expanded by the expandable part.
In some embodiments, the mesh mechanism includes the filiform containing the first ring, and the releasing mechanism includes Rotatable pin and the second ring in the connecting rod distal portions, second ring are engaged with one end of the pin, and described first Ring is captured by the other end of the pin, and the translation of the connecting rod causes the pin to rotate, and is made described in the first ring disengaging Pin, discharges the implantation material.
Technology described herein and its attribute and adjoint advantage are combining the following detailed description for cooperating attached drawing, Wherein representative embodiment by way of example under, best will be appreciated and understand.
Detailed description of the invention
Fig. 1 shows the schematic diagram that is used to convey implantation material system to patient's body consistent with this paper concept of the invention.
Fig. 2 shows the systems for convey implantation material to patient's body consistent with this paper concept of the invention, and including The schematic diagram of one or more functions element.
Fig. 3 shows the side sectional view of the implantation material based on spring ring consistent with this paper concept of the invention.
Fig. 4 and Fig. 4 A shows the implantation material transportation system consistent with this paper concept of the invention.
Fig. 5 A-C shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Transparent perspective view.
Fig. 6 A-B shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Transparent perspective view.
Fig. 7 shows implantation material and the half of releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Transparent stereo figure.
Fig. 8 A-B shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Side sectional view.
Fig. 9 A-B shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Side sectional view.
Figure 10 A-B shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Side sectional view.
Figure 11 A-B shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Side sectional view.
Figure 12 A-B shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Side sectional view.
Figure 13 A-B shows implantation material and releasing mechanism interface in the implantation material transportation system consistent with this paper concept of the invention Transparent perspective view.
Figure 14 shows the side view of the medical instrument central axis consistent with this paper concept of the invention.
Figure 15 shows the perspective view of the spring ring of the implantation material consistent with this paper concept of the invention.
Figure 16 shows the perspective view of the spring ring of the implantation material consistent with this paper concept of the invention.
Specific embodiment
It will be described in detail the embodiment of this technology now, case regular meeting is illustrated with attached drawing.Identical reference number It is used for the same or similar part throughout the drawings.
It is to be understood that word " comprising " herein (and other any forms of this word, such as " wrapped Include "), " having " (and other any forms of this word, such as " having had "), " including " (and this word other What form, for example, " included), or " containing " (and other any forms of this word, such as " included "), be for The existing feature of statement, integer, step, operation, element and/or component etc., but be not excluded for showing or increasing one or more Other feature, integer, step, operation, element, component and/or their combination.
Although will be further appreciated that first, second, the clauses such as third can be used to describe various limits herein System, element, component, region, level and/or section, these limitations, element, component, region, level and/or section should not be by The limitation of these clauses.These clauses are only used for distinguishing a limitation, element, component, region, level or section and another Limitation, element, component, region, the difference of level or section.Therefore, first limitation being discussed below, element, component, area Domain, level or section can be referred to as the second limitation, element, component, region, level or section, without departing from what is applied at present Guideline.
It will be further appreciated that when an element is referred to as " ", " subsidiary ", " connection " or " pairs of " to another member When plain, it can directly over or be higher than, or connection, or intermediate existing for another element or one or more in pairs Element.On the contrary, when an element is referred to as " directly existing ", " directly subsidiary ", " being directly connected to ", or " directly in pairs " arrive another member When plain, neutral element is not present.Other words for describing relationship between element should be solved in similar following mode Release (for example, " between " relative to " directly between ", " adjacent " and " direct neighbor " etc.).
It will be further appreciated that be referred to as " " when the first element, when "upper" and/or " inside " second element, First element can be positioned so that: in the inner space of second element, (for example, second in certain part of second element In the wall of element);On the externally and/or internally surface of second element;And the combination of above-mentioned one or more forms.
As used herein, word " neighbouring " should include for a reference cell or other positions, on position It is close, above, inside, and/or enter.
Space relative terms, such as " ... under ", " ... below ", " being lower than ", " being higher than ", " above " and class As word can be used for the relationship for describing an element and/or feature and other elements (s) and/or feature (s), such as institute in figure It enumerates.It will be further appreciated that space relative terms are intended to comprising the use and/or operating device other than attached drawing description Different modes.For example, being described as be in other elements and features before if the device in a figure is reversed " ... below " and/or " ... under " element will become positioned at other elements or features " above ".The device can In addition (such as be rotated by 90 ° or other orientation) is positioned, and corresponding explanation is made for space description here.
Term " reduction " used herein, " reduction ", " reduction " and similar word, the reduction including amount, including subtract Less to zero.A possibility that reducing by an example should include preventing its generation.
Whether term "and/or" herein is two groups of specific functions of specific confirmation or element with or without another It is a.For example, " A and/or B ", which is regarded as specific confirmation, shows each (i) A;(ii) B, and (iii) A and B, herein as figure In be each individually to set.
" diameter " word is regarded as one and connects for describing a non-circular geometry, geometry herein The illusion diameter of a circle of its nearly description.For example, when description cross section, such as the cross section of a component, term " diameter " application To describe to have the imaginary diameter of a circle of same circular transverse cross section product with module transverse section.
Term used herein: a component " long axis " and " short axle " are to respectively refer to that institute's component can be surrounded completely most The length and diameter of the hypothesis cylindrical body of small size.
It is understood that certain features of the invention, for the sake of clarity, in the described in the text of different embodiments, It may also illustrate in individual event scheme in a joint manner.Opposite, multiple features in the present invention, for simplification, in individual event The described in the text of scheme, it is also possible to separate or with any suitable sub-combination explanation.Such as, it is possible to understand that any right All features (no matter independence or subordinate) stated in it is required that, can be combined with any given mode.
System it provided herein is the one or more implantation materials of conveying to patient's body, device and method, such as accurately Conveying one or more implantation spring rings in ground are into aneurysm.A kind of medical delivery system includes the plant of one or more implantation materials Enter object transportation system, each implantation material includes an engaging portion.Implantation material transportation system further includes a releasing mechanism and one A controlling mechanism.Relieving mechanism includes a connecting rod, and the other parts and implantation material of the connecting rod or the releasing mechanism are nibbled Part is closed to be meshed.Controlling mechanism is constructed and arranged as control link, promotes releasing mechanism in the scheduled position of patient's body It is detached from from implantation material.System and equipment in concept of the present invention can be constructed and arranged as discharging rapidly implantation material, so Allow to be implanted into the accuracy for being transported to patient's body predetermined position.
Referring to Fig.1, schematic diagram explain consistent with a concept of the present invention conveying implantation material to patient system.System System 10 includes an implantation material transportation system 100, which includes controlling mechanism 120, releasing mechanism 140 and implantation material 160. Implantation material 160 includes mesh mechanism 170.The releasing mechanism 140 that is constructed and arranged to of system 10 allows operator (for example, one It is implanted into clinician) implantation material 160 is accurately transported to expected position, such as when implantation material 160 includes one or more Vascular occluding device (such as a vaso-occlusive coils), bracket, overlay film frame and/or drug delivering implant, and work as Releasing mechanism 140 is constructed and arranged to discharge rapidly implantation material 160 (for example, avoiding or being greatly decreased activation controlling mechanism Delay between 120 and release implantation material 160).In some case study on implementation, system 10 is constructed and arranged to accurate delivery plant Enter in object 160 to aneurysm, such as cerebral aneurysm.In addition, system 10 can be constructed and arranged to be conveyed implantation material to being selected from One or more positions in the following group: occlusion intravascular or occluded before it is intravascular, such as the cerebrovascular, it is clear that i.e. will What is occluded is intravascular, above, the inside, and/or enter another patient's body position, and these one or more of positions Combination.Releasing mechanism 140 may include a translatable conduit and connecting rod 141.As described herein, connecting rod 141 or Another part of releasing mechanism 140 is meshed with the mesh mechanism 170 of implantation material 160, such as advances and/or contract in device 100 Hui Shi keeps the relative position of implantation material 160 and releasing mechanism 140 to stablize constant, until the operation of one or more systems 10 Person confirms that implantation material 160 has entered and properly implants position, and releasing mechanism 140 can be detached from or otherwise from implantation at this time (implantation material 160 " being released ") is separated in object 160.Device 100 and system 10 in this paper concept of the invention are constructed and arranged as The stabilisation implant 160 when confirming one or more positions, then in an accurate position release implantation material 160 (for example, In It is implanted on the exact position of cerebral aneurysm or other intracerebrals).
Device 100 may include an axis, and axis 110 at least surrounds a part of (such as sliding is surrounded) connecting rod 141 or releases The other parts of mechanism 140 are put, axis 110 includes proximal end 111, distal portions 115 and distal end 112.In some embodiments, axis 110 at least part surrounds at least part of controlling mechanism 120.In some embodiments, at least part of axis 110 At least part of (for example, all or part of of distal portions 115) encirclement implantation material 160.
Controlling mechanism 120 is built and is arranged as control link 141, such as translation (such as advancing, and/or retraction) or rotation Turn connecting rod 141.The adequately translation of connecting rod 141 and/or rotation (for example, translation and/or rotation of a predetermined quantity) cause to plant Enter object 160 and is released (such as separating from connecting rod 141 or 140 another part of releasing mechanism).Connecting rod 141 can connect (for example, solid Surely connect) in a part of controlling mechanism 120, such as when connecting rod 141 is attached, welding, curling is riveted and/or is combined Onto an axis, shell, another part of pipe and/or releasing mechanism 140.
In some embodiments, controlling mechanism 120 includes the handle comprising mechanical component (for example, mechanical component Including one or more cams, gear, motor and/or connecting rod), the handle is configured as translation and/or swivel link 141, Such as handle 101 mentioned below, referring to following Fig. 2.In some embodiments, controlling mechanism 120 is operationally connected to Connecting rod 141, and it is releasably connected to axis 110, so that controlling mechanism 120 can be separated from axis 110, and then grasped Make to translate and/or swivel link 141 is so that controlled reservoir implantation material 160.In some embodiments, controlling mechanism 120 releaseably connecting shaft 110.
System 10 can further comprise that one or more blood vessel guides, seal wire and/or access conduit (such as microtubular), such as Access device 300 shown in figure.For example, access device 300 may include vessel catheter sheath, for example one is gathered including high density Ethylene (HDPE) and/or polyacrylic guide sheath.Access device 300 may include one or more standards and/or exchange length The interventional guide wire of degree.Access device 300 may include a guiding catheter, and for example, at least a microtubular is (for example, internal diameter exists Between 0.015 and 0.025 inch, for example internal diameter is about 0.017 inch).
System 10 can also include one or more vision facilities, as illustrated in the drawing vision facilities 400.Vision facilities 400 may include one or more image devices in being selected from the group: fluorescope, X-ray production apparatus, CT scanner, nuclear magnetic resonance figures As instrument, ultrasonography instrument and their combination.In some embodiments, vision facilities 400 includes at least one fluorescence Mirror is implanted into the patient for guide device 100, and the positioning implants 160 in implantation.One or more of device 100 Component may include a visual marker (for example, radiopaque label, magnetic and/or visible label of ultrasound), such as one A visual marker is located in be selected from the group in a component the inside, above and/or in vivo: mesh mechanism 170 and/or plant Enter the other parts of object 160, the other parts of connecting rod 141 and/or releasing mechanism 140;Axis 110;And it is a kind of or more among the above The combination of kind.
In some embodiments, axis 110, controlling mechanism 120, releasing mechanism 140 and/or implantation material 160 have following The similar construction and arrangement, referring to one or more figures of Fig. 2-16.In some embodiments, implantation material 160 Mesh mechanism 170 has similar structures and layout with one or more engaging portion 171-183 what follows.
In some embodiments, axis 110 includes a knitted parts, referring to following Fig. 4.In some embodiments In, axis 110 may include one or more plastics and/or metal material, such as one of be selected from the group material: stainless steel;Shape Shape memory metal;Nitinol;Polymer;Shape-memory polymer;And above-mentioned one or more combinations.
In some embodiments, controlling mechanism 120 includes a part of at least axis 110, such as coaxial 110 proximal part It is configured as separating from the remainder of axis 110.In some embodiments, controlling mechanism 120 includes the close end of connecting rod 141 Point, and and/or engaged by the proximal part of connecting rod 141, such as when connecting rod 141 is pushed into discharge implantation material 160.Control machine System 120 can be constructed and arranged as retraction connecting rod 141, as described by multiple pictures following herein.Controlling mechanism 120 can be with It is configured as promoting connecting rod 141, such as when controlling mechanism 120 includes a knob, control-rod, slide or other operable companies It is connected to the control mode of 141 proximal part of connecting rod.In some embodiments, controlling mechanism 120 is configured the proximal end with axis 110 Part is engaged, the translation (advance and/or retract) such as axis 110 relative to connecting rod 141.
In some embodiments, controlling mechanism 120 includes connector, connector 122 as described below, the connection Controlling mechanism 120 can be connected to the proximal part of axis 110 by device 122.Connector 122 can be fixed ground conjugate control mechanism 120 And/or axis 110 is fixedly engaged, and be releasably engageable the other parts of controlling mechanism 120 and axis 110, so by applying Power overcomes friction engagement, and controlling mechanism 120 is separated from axis 110.In addition, connector 122 connects in which can be fixed To a part of controlling mechanism 120 and axis 110, and it is constructed and arranged to (for example, at an opposite midpoint) after being destroyed, made Controlling mechanism 120 is separated from axis 110.After the separation of axis 110, controlling mechanism can be translated and/or rotate to cause connecting rod 141 Association translation and/or rotation.
In some embodiments, releasing mechanism 140 includes a part of at least axis 110, such as when axis 110 includes one Or multiple grooves or hole, the groove or hole be constructed and arranged as stabilisation implant 160 and/or by releasing mechanism 140 come Help discharges implantation material 160, as described below.Releasing mechanism 140 can be configured to using one of the following group or various ways To discharge implantation material 160 (for example, being deployed on one scheduled position of implantation material): vibrational energy, the fatigue of component, light (example Such as, via one or more optical fiber), tension compresses, and torsion, torque is heated or cooled (for example, the variation of temperature causes phase Transformation or thermal expansion or thermal contraction);The injection of fluid or solid, displacement of the connecting rod 141 relative to axis 110, sense electronics stress, Magnetism, a piezoelectric elements, a piezoresistance element, biochemical reaction, a hydrophily component, a bioactivity at Point, and/or chemical reaction.
Connecting rod 141 may include a kind of metal and/or a kind of plastic material, such as a kind of material selected from the group below: stainless steel surpasses Elastic metallic, Nitinol, marmem, shape-memory polymer, polymer and group one or more in them It closes.Connecting rod 141 may include an outer diameter (OD) between 0.001 inch and 0.005 inch, such as one about 0.002 The outer diameter of inch.In some embodiments, the internal diameter (ID) of the outer diameter (OD) of connecting rod 141 and axis 110 setting size be for Engage axis 110 to frictionally with connecting rod 141.This frictionally engagement can be configured to prevent the meaning of connecting rod 141 Outer translation.In some embodiments, the proximal part of connecting rod 141 and/or distal portions include one and other portions of connecting rod 141 Point different attributes, such as a different attribute in being selected from the group: material, diameter, cross section profile and they in one or Multiple combinations.
In some embodiments, connecting rod 141 includes an amplifier section, such as enlarged described below 144, Include spherical shape, cylindrical and/or other geometries part, diameter it is bigger than the neighbouring part of connecting rod 141 (connecting rod 141 A part is located just at proximal end or the distal portions of 4 amplifier sections 144).One or more amplifier sections 144 can be set to In the distal end of connecting rod 141 or at least on distal portions.Each amplifier section 144 can connect (for example, being releasably attached) and arrive On mesh mechanism 170, with stabilisation implant 160, and then separated from mesh mechanism 170, so that implantation material 160 is desired It is accurately discharged on implantation position.
As described above, implantation material 160 includes one or more implantable devices, such as one, it is two or more to be selected from down Implantable device in group: vascular occluding device, bracket, overlay film frame, drug delivering implant and they in one or more A combination.In some embodiments, implantation material 160 includes a vascular occluding device, and the vascular occluding device includes One or more occlusive coils, as described below, referring to Fig. 3.In some embodiments, implantation material 160 includes an elasticity Unbiased shape, as described below, referring to Fig.1 5 and/or 16.
Implantation material 160 may include one or more filament, such as filament described below 163 and/or 180.Some In embodiment, implantation material 160 includes elastic filament 163 described below, and referring to Fig. 3, the elastic filament includes that drawing is complete Portion or part mesh mechanism 170 (such as all or part of filament 180 and/or ring 171), into spring ring (such as bullet Spring coil 161) fexible bias pressure or implantation material 160 be released the other hollow spaces of the implantation material after mechanism 140 discharges 160.
In some embodiments, mesh mechanism 170 includes an amplifier section, such as amplifier section 172, does not scheme to show Show, but be described below, the amplifier section includes a spherical shape, cylindrical or other geometries part, diameter It is bigger than the neighbouring part of mesh mechanism 170 that (a part of mesh mechanism 170 is located just at the proximal end or remote of 4 amplifier sections 172 End).One or more amplifier sections 172 can be positioned on a proximal end or at least one proximal part of mesh mechanism 170.Each Amplifier section 172 can connect (such as releasable connection) to releasing mechanism 140, with stabilisation implant 160, and then from It is separated on releasing mechanism 140, so that implantation material 160 accurately discharges on desired implantation position.
One or more components on device 100 may include the geometry of a fexible bias pressure, such as a component A kind of fexible bias pressure of state in being selected from the group: compression (for example, distensible compressive state), expansion (such as expansion state Can be compressed), it coils or with other curved states (for example, the bending state that can be straightened), straight line is (for example, can disk Around or curved linear state) and they one of or multiple combinations.In some embodiments, device 100 includes one A fexible bias pressure component, the component include one of to be selected from the group material a: thermal setting materials, stainless steel, Nitinol, And they one of or multiple combinations.
In some embodiments, releasing mechanism 140 and/or implantation material 160 are constructed and arranged as reference as described below It illustrates any one or more of in 2-13.
In some embodiments, implantation material 160 is constructed and arranged as described below referring in diagram 14-16 any one Kind is a variety of.
In some embodiments, the one or more components of system 10 include one or more sensors, energy converter or Other function element, it is as described below referring to Fig. 2.
Referring to Fig. 2, schematic diagram explains a conveying implantation material consistent with concept of the present invention to patient's body, and wraps The system of the element containing one or more functions.System 10 includes device 100, and may include access device as described above 300 and/ Or imaging device 400.Device 100 includes controlling mechanism 120, releasing mechanism 140, implantation material 160, axis 110 and other assemblies, and And these each can be similarly constructed and be arranged as above-mentioned similar component referring to Fig.1.
Device 100 in Fig. 2 may include a handle, handle 101 as shown in the figure.Handle 101 may include a fixation Connection or moveable handle.Releasing mechanism 120 is at least a part of to be positioned on handle 101.Handle 101 may include One or more manipulation devices, manipulation device 101a, such as button, knob, lever, trigger, switch, cam and/or other Mechanical, electric, chemical and/or fluid control machine system.In some embodiments, manipulation device 101a includes a manipulation Device is constructed and arranged as promoting, and retracts and/or rotate one or more below: axis 110, connecting rod 141 and/or machine for releasing Another part of system 140.
The device 100 of Fig. 2 may include one or more functions element, such as the function element 219a of axis 110 (such as schemes Show the proximal part for being located in axis 110), the function element 219b of axis 110 (such as illustrated position is in the distal portions of axis 110 115), the element 229 of controlling mechanism 120, (it can be positioned in connecting rod 141 to the function element 249 of releasing mechanism 140 It is upper, interior or near) and/or implantation material 160 function element 269, the function element 279 of mesh mechanism 170.Function element 219a, 219b, 229,249,269 and/or 279 may include a sensor, energy converter or other function element.It is one or more Function element 219a, 219b, 229,249,269 and/or 279 kinds can be operatively coupled on handle 101 via conduit, In figure without display but one or more of conduits can be selected from the group: conducting wire, optical fiber, fluid delivery tube, mechanical linkage, And they one of or multiple combinations.
In some embodiments, one or more functions element 219a, 219b, 229,249,269 and/or 279 include One sensor, such as a sensor in being selected from the group: biosensor, such as blood sensor, such as a blood Gas content sensor;Capacitance sensor, such as voltage sensor or current sensor;Magnetic Sensor, such as a Hall effect Inductive sensing device, mechanical pick-up device, such as strain gauge, accelerometer or flow sensor, such as ultrasonic flow sensor, chemistry Sensor and they one of or multiple combinations.
In some embodiments, one or more functions element 219a, 219b, 229,249,269 and/or 279 include One energy converter.Term " energy converter " described herein should be understood comprising any reception energy or any input, and generate one One component of a output or the combination of component.For example, energy converter may include an electrode, for receiving electric energy, and will be electric Tissue (for example, according to size of electrode) can be assigned to.In some configurations, electronic signal is converted into any by an energy converter Output, such as light (for example, energy converter comprising a light emitting diode or light bulb), sound is (for example, super to deliver comprising configuring The piezocrystal transducer of acoustic wave energy), pressure, thermal energy, cold energy, chemical energy, mechanical energy (e.g., including a motor or spiral shell The energy converter of spool), magnetic energy, and/or another electric signal (for example, bluetooth or other wireless communication units).In addition, one is changed Physical quantity (for example, variation of physical quantity) can be converted into electric signal by energy device.One energy converter may include any energy transmitting Energy and/or reagent are configured as transmitting one of the following group or multiple kinds of energy to structural component, such as an energy converter To tissue: to the electric energy of tissue: (for example, an energy converter includes one or more electrodes), to tissue light energy (for example, One energy converter includes a laser, light emitting diode and/or optical module, such as lens or prism), to the mechanical energy of tissue (for example, an energy converter includes a tissue manipulation element), the sound to tissue can be (for example, an energy converter includes a pressure Transistor);Chemical energy, electromagnetic energy, magnetic energy and they one of or multiple combinations.
In some embodiments, function element 219a, 219b, 249,269 and/or 279 includes one or more visual Change element, such as one or more radiopaque labels, magnetic mark and/or ultrasonic wave witness marking, the label are configured It is visualized by imaging device 400.(such as determine that the position of one or more components or each item parts of equipment 100 are helped Help the positioning and deployment of implantation material 160).
It is the side sectional view of the implantation material based on spring ring consistent with concept of the present invention referring to Fig. 3.In figure Show implantation material 160, the implantation material 160 of the implantation material and Fig. 1 there are similar construction and arrangement.Implantation material 160 includes one A or multiple spring rings, spring ring 161.Spring ring 161 may include first part 161a (for example, first spring ring) and second Part 161b (for example, second spring ring).Second part 161B can be soldered to first part 161a (for example, solder joint is big 3 rings of about each spring ring).One circular tip portion, ball 162 are fixedly joined to the end of spring ring 161 End, its distal end for being positioned in implantation material 160 of the ball, and be fixedly connected to filament 163 (such as diameter is about 0.001 Inch polypropylene fibre) end.In some embodiments, filament 163 is thin including a plurality of filament, such as two or more pieces Silk advances on being distally connected to ball 162, and towards the proximal end of implantation material 160 (for example, along with every filament in a side-by-side fashion Proximal end be connected to ring 171).Ball 162 may include polypropylene and/or other plastic materials.Ball 162 may include a kind of bonding Agent, such as a ultraviolet curing adhesive are formed as spherical shape.162 at least part of ball be it is visual (such as not Radioparent) or it may include a visual label (such as radiopaque marker).Implantation material 160 includes nibbling Conjunction mechanism 170, the mesh mechanism include the filament 180 for being configured to a ring 171, and the filament is fixedly connected (example Such as, in anchor joint) arrive filament 163 proximal end.Ring 171 may include plastics or metal material.In some embodiments, ring 171 include Nitinol, such as when ring 171 includes the cyclic annular filament that an outer diameter is about 0.001 inch.In Fig. 3, work as ring 171 when extending beyond the proximal end of spring ring 161, and filament 163 is as shown in the figure in a tensional state (for example, as described herein If engaged with releasing mechanism 140, the two will separate).Filament 163 is stretchable, and is biased to so that ring 171 All be partially or mostly positioned on spring ring 161 when no tension is applied to ring 171 (such as passes through releasing mechanism 140, tension can cause filament 163 to stretch).Ring 171 is configured as engaging with releasing mechanism 140, and by controlling from release It is detached from mechanism 140 so that implantation material 160 is accurately implanted into (for example, accurately planting in aneurysm on expected position Enter).
In some embodiments, second part 161b includes the outer diameter smaller than first part 161a.As shown here Two part 161b can be configured as to be received by axis 110 and/or the sliding of releasing mechanism 140.In some embodiments, spring ring First part 161a includes about 10 mm outer diameters, and spring ring second part 161b includes about 7.5 millimeters of outer diameter.Spring ring first Part 161a and spring ring second part 161b can be same direction winding, as shown in Figure 3.In some embodiments, The winding direction and spring ring first part 161a of the second part 161b of spring ring is opposite.
Shown in following Fig. 4-13, a part (for example, a part of ring 171) of mesh mechanism 170, which may show to extend, to be surpassed The proximal end of implantation material 160 out, such as when implantation material 160 is engaged with releasing mechanism 140, and releasing mechanism 140 is applied tension to and is nibbled Conjunction mechanism 170 (for example, stretch ring 171 and/or filament 163).Once being discharged from releasing mechanism 140, the whole of mesh mechanism 170 Or most of other hollow spaces (such as fexible bias pressure filament 163) that can be drawn into spring ring or implantation material 160.
Shown in same following Fig. 4-13, the proximal end face of implantation material 160 (such as the proximal end face or bullet of mesh mechanism 170 The proximal end face of spring coil 161) it is possibly shown as being deviated from the distal end of axis 110 112 (for example, a notch appears in 112 Hes of distal end Between the proximal end face of implantation material 160).When no display notch in some embodiments, (for example, implantation material 160 is close End surfaces are flushed with the distal end of axis 110) diagram in notch can provide clear explanation.
Referring to Fig. 4 and 4A, illustrates the medical transport consistent with concept of the present invention and send device.Fig. 4 is the one of device 100 A side sectional view, and Fig. 4 A is the translucent of the part amplification of 140 interface of releasing mechanism on implantation material 160 and device 100 Perspective view.Device 100 includes controlling mechanism 120, releasing mechanism 140, implantation material 160 and other assemblies, and every in these One can have similar construction and arrangement with the above-mentioned similar component with reference to Fig. 1.As shown in figure 4, implantation material 160 includes bullet Spring coil 161, ball 162, filament 163 and mesh mechanism 170, mesh mechanism contain the filament 180 for being configured to a ring 171.Bullet Spring coil 161 may include first part 161a and second part 161b, as shown in reference Fig. 1.Device 100 may include axis 110, the axis includes proximal end 111, distal portions 115 and distal end 112, and at least about a part of connecting rod 141.Some In embodiment, axis 110 include one or more (such as distal portions 115) outer diameters between 0.011 inch and 0.014 inch it Between part.
In some embodiments, axis 110 includes part that an is braiding or otherwise reinforcing, such as works as axis 110 include torque wire 113 as shown in the figure (for example, the metal and/or plastic filament of one or more helical geometries, and Positioned at the outer wall of 110 distal portions of axis, into outer wall and/or it is located at inner wall).Torque wire 113 may include a monofilament lines, example Such as about 0.0015 inch of monofilament lines of diameter.Torque wire 113 may include multi cord, for example, diameter between 0.00125 inch and Multi cord between 0.0015 inch.Torque wire 113 may include a spiral geometry.
Axis 110 may include one or more tubular structures for surrounding axis 110, outer tube 114 as shown.Outer tube 114 May include material selected from the group below: polytetrafluoroethylene (PTFE) (PTFE), poly terephthalic acid (PET), heat-shrinkage material and they in One or more combinations.The thickness of outer tube 114 can be between 0.0010 inch and 0.0025 inch, a such as thickness It is managed for 0.0016 inch of PTFE tube or with a thickness of 0.0020 inch of PET.
Releasing mechanism 140 includes connecting rod 141, and 141 proximal part of connecting rod is operatively coupled to controlling mechanism 120, and And its being released property of distal portions be connected to mesh mechanism 170, as described below.Releasing mechanism 140 includes bolt 142, and bolt 142 can It is fixedly joined to axis 110 (such as adhering to, hot adhesion, riveting or the like).The winding of ring 171 bolt 142 (such as around bolt 142 about 90 ° of windings), and connecting rod 141 passes through ring 171, as shown, making ring 171 by between connecting rod 141 and bolt 142 Interface captures, and consolidates implantation material 160, sufficiently bounces back until connecting rod 141 passes through controlling mechanism 120, as described herein.Ring 171 Release is so that implantation material 160 is accordingly discharged (such as being deployed in a scheduled implantation position).
Controlling mechanism 120 may include an attachment element, connector 122, and connector 122 prolongs with axis to frictionally 123 (belonging to controlling mechanism 120) of engagement is stretched, the position of connecting rod 141 is maintained.Connector 122 can be configured to releasably engage Axis 110 and/or outrigger shaft 123, so that by manipulation and control mechanism 120 (such as retracting) come the connecting rod 141 that bounces back.In addition, connection Device 122 can be constructed and arranged to disconnect (such as about in its central part), allow controlling mechanism 120 relative to axis 110 translations.Connector 122 may include a label, such as one can indicate the point of application to disconnect the label of device 122.In In some embodiments, connector 122 may include heat-shrinkage material, such as heat-shrinkable polyethylene terephthalate (PET) (such as with a thickness of 0.0002 inch of PET).In some embodiments, connector 122 includes a rigid plastic pipes Or metal tube, such as hypo pipeline section.In some embodiments, axis extends 123 proximal end (continuous) parts including axis 110, institute Proximal part is stated to be configured as that (for example, cutting or otherwise separation) can be separated with the rest part of axis 110.
The proximal end 111 of axis 110 can be connected to outrigger shaft 123 (as shown in Figure 4) by connector 122, such as work as outrigger shaft 123 can be constructed and arranged to divide with the proximal end 111 of axis 110 when including independent pipe (such as metal or a plastics rigid pipe) From.Alternatively, axis extension 123 can simply include the extension of axis 110, which is configured to remaining from axis 110 (more distal end) is partially separated (such as cutting).Connector 122, which can be constructed and arranged to disconnect at point therebetween, (such as to be applied Enough bending forces) so that shaft extension point 123 is separated from axis 110, and translates connecting rod 141, such as this paper institute It states.Make outrigger shaft 123 from axis 110 alternatively, 122 (if there is) of connector, outrigger shaft 123 and/or axis 110 can be configured to rotation Separation.
In some embodiments, one or more openings, opening 117 are positioned in the 115 (example of distal portions of axis 110 Such as on same one side or over there), to assist the manufacture of device 100 (for example, the inner cavity of axis 110 is allowed access into, to simplify ring The winding of 171 pairs of bolts 142).Ring 171 can be placed on the proximal end of bolt 142, later, even by opening 117 (on one side or both sides) Bar 141 can be on ring 171, acquisition loop 171 to bolt 142.In these embodiments, opening 117 can be then heat-shrinked Pipe or the covering of other outer tube (not shown).In some embodiments, opening 117 is coated after bolt ring 171 winds bolt 142 Lid, such as pass through heat-shrinkable tube or other outer tubes.
It is the partially transparent perspective view between implantation material and the releasing mechanism of implantation material transportation system referring to Fig. 5 A-C, with Concept of the present invention is consistent.The implantation material transportation system 100 of Fig. 5 A-C and the device 100 of Fig. 1 and/or any dress mentioned herein Setting 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160. Implantation material 160 includes mesh mechanism 170 comprising the filiform 180 in ring 171 as shown in the figure.Device 100 may include axis 110, Including distal end 112, and at least surround a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, and proximal part is operably attached to controlling mechanism 120, and at it Distal portions are releaseably attached to mesh mechanism 170, as described below.Connecting rod 141 is from controlling mechanism 120 towards implantation material 160 extensions and the protruding parts 149 including its distal end.Ring 171 is positioned in the outer wall around axis 110 and opens with axis 110 Mouth 117 engages.Opening 117 may include inclined geometric shapes as shown in figures 5 a-c.In fig. 5, protruding parts 149 (and even Bar 141) in the position fully advanced, wherein 149 connecting shaft of protruding parts, 110 distal end inner wall is to opening 117, so that ring 171 It is prevented from leaving opening 117, thus stabilisation implant 160.In figure 5B, connecting rod 141 retracts (such as by as described herein Controlling mechanism 120) so that ring 171 is no longer limited in opening 117, this allows implantation material 160 to be released as shown in Figure 5 C.
In some embodiments, ring 171 includes fexible bias pressure, this fexible bias pressure is configured to after connecting rod 141 retracts Ring 171 is set to leave opening 117.
It is the partially transparent perspective view between implantation material and the releasing mechanism of implantation material transportation system referring to Fig. 6 A-B, with Concept of the present invention is consistent.The implantation material transportation system 100 of Fig. 6 A-B and the device 100 of Fig. 1 and/or any dress mentioned herein Setting 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160. Implantation material 160 includes mesh mechanism 170 comprising the filiform 180 in ring 171 as shown in the figure.Device 100 may include axis 110, Including distal end 112, and at least surround a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, and proximal part is operably attached to controlling mechanism 120, and distal end is then Be formed as cooperating with the protruding parts 154 of releasing mechanism 140 and (such as in conjunction with the geometry to match with two, such as retouch below The cooperation slope section stated).The distal end of connecting rod 141 may also include recess portion 148.Protruding parts 154 can be from axis as shown in the figure The protruding parts of 110 inner walls, or the fixed separate part for being attached at axis 110.The distal end of protruding parts 154 and connecting rod 141 It may include the inclined geometric shapes to match as shown, so that working as the distal advancement of connecting rod 141 and ring 171 being made to be located in recess portion In 148, and when connecting rod 141 and protruding parts 154 contact, ring 171 is fixed to device 100, stabilisation implant 160.Such as Fig. 6 B Shown, connecting rod 141 can advance (such as by controlling mechanism 120 as described herein), along 154 ramp of protruding parts branch Into until the distal end 112 of axis 110 is left in the distal end of connecting rod 141, implantation material 160 is unfolded in release ring 171.In addition, ring 171 can be with It is released by retracting connecting rod 141, until the distal end of connecting rod 141 no longer passes through ring 171.
It is the partially transparent perspective view between implantation material and the releasing mechanism of implantation material transportation system, with this hair referring to Fig. 7 Bright concept is consistent.The implantation material transportation system 100 of Fig. 7 and the device 100 of Fig. 1 and/or any device 100 mentioned herein have Similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160.Implantation material 160 include mesh mechanism 170 comprising the filiform 180 in ring 171 as shown in the figure.Device 100 may include axis 110, including remote End 112, and at least surround a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, and proximal part is operably attached to controlling mechanism 120, and at it Distal portions are releaseably attached to mesh mechanism 170, as described below.Releasing mechanism 140 includes sleeve 159 and hole 119. Hole 119 is located on the distal end of axis 110 (for example, the atrium end for being simply axis 110).Sleeve 159 may include from axis The protruding parts of 110 inner wall or the separate part for being fixedly attached to 110 inner wall of axis.Ring 171 passes through hole 119, and connecting rod 141 pass through ring 171 and enter sleeve 159, as shown, thus stabilisation implant 160 of acquisition loop 171.When connecting rod 141 sufficiently contracts Returning (for example, passing through controlling mechanism 120 as described herein) causes ring 171 to discharge from connecting rod 141.The release of ring 171 is to be unfolded Implantation material 160.
It is the lateral parts perspective view between implantation material and the releasing mechanism of implantation material transportation system referring to Fig. 8 A-B, with Concept of the present invention is consistent.The implantation material transportation system 100 of Fig. 8 A-B and the device 100 of Fig. 1 and/or any dress mentioned herein Setting 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160. Implantation material 160 includes mesh mechanism 170 comprising the filiform 180 of ring 171 as shown in the figure.Device 100 may include axis 110, packet Distal end 112 is included, and at least surrounds a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, is operably attached to controlling mechanism 120 on proximal part, and Its distal portions is releaseably attached to mesh mechanism 170, as described below.Releasing mechanism 140 includes protruding parts 154 '. Protruding parts 154 ' can be fixedly attached to (such as being adhesively attached, be thermally bonded, swaged forging etc.) axis 110 and/or it and can be Protruding parts from 110 inner wall of axis.Protruding parts 154' may include wedge geometry as shown in the figure, engage ring 171.It releases Putting mechanism 140 further includes the wedge-shaped enlarged 146' on 141 distal end of connecting rod.Advance when connecting rod 141 is in shown in Fig. 8 A When state, enlarged 146' makes ring 171 keep the fixation position (being fixed with protruding parts 154') with mesh mechanism 170, from And stabilisation implant 160.The retraction (for example, pass through as described herein controlling mechanism 120) of connecting rod 141 allows ring 171 can be from prominent Position 154' is detached from out, (such as being slidably detached from from protruding parts 154' when ring 171 is advanced along its slope), to release Put implantation material 160.
It is the lateral parts perspective view between implantation material and the releasing mechanism of implantation material transportation system referring to Fig. 9 A-B, with Concept of the present invention is consistent.The implantation material transportation system 100 of Fig. 9 A-B and the device 100 of Fig. 1 and/or any dress mentioned herein Setting 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160. Implantation material 160 includes mesh mechanism 170 comprising the port 175 comprising recess portion as shown in the figure.Device 100 may include axis 110, including distal end 112, and at least surround a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, is operably attached to controlling mechanism 120 on proximal part, and Its distal portions is releaseably attached to mesh mechanism 170, as described below.Connecting rod 141 is from controlling mechanism 120 towards implantation Object 160 extends.Releasing mechanism 140 further includes amplifier section 144, such as spherical or other as illustrated by the attachment of tether 151 To the enlarged of axis 110.The distal portions of connecting rod 141 are between amplifier section 144 and port 175.Amplifier section 144, The size and/or other parts of the distal portions of port 175 and connecting rod 141 are constructed and are laid out in when connecting rod 141 is in Fig. 9 A Shown in progressive position when, frictionally connectivity port 175 of amplifier section 144, benefit obtains mesh mechanism 170, discharges implantation material 160.The retraction (such as via controlling mechanism 120 as described herein) of connecting rod 141, by mesh mechanism 170 from amplifier section 144 The frictional engagement of application releases (as shown in Figure 9 B).Tether 151 keeps position (example of the amplifier section 144 relative to axis 110 Such as, prevent amplifier section 144 mobile to distal end).
0A-B referring to Fig.1 is the lateral parts perspective view between implantation material and the releasing mechanism of implantation material transportation system, with Concept of the present invention is consistent.The implantation material transportation system 100 of Figure 10 A-B and the device 100 of Fig. 1 and/or mentioned herein any Device 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160.Implantation material 160 includes mesh mechanism 170, and mesh mechanism 170 includes the anchoring element of filiform 180 and elastic biasing: anchor 174, anchor 174 is located at the proximal end (as shown in the figure) of filiform 180 or at least in a part of proximal end.Device 100 may include axis 110, Axis 110 includes the distal portions 115' of the nozzle shape with distal end 112, and at least surrounds a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, is operably attached to controlling mechanism 120 on proximal part, and Its distal portions is releaseably attached to mesh mechanism 170, as described below.Connecting rod 141 is from controlling mechanism 120 towards implantation Object 160 extends.The distal end of connecting rod 141 prevents it from leaving nozzle shape to 174 applied force of anchor so that anchor 174 engages the wall of axis 110 Distal portions 115'(it is as shown in Figure 10 A), capture mesh mechanism 170 and thus stabilisation implant 160.The retraction of connecting rod 141 (such as via controlling mechanism 120 as described herein) allows anchor 174 to shrink (for example, being transferred to the compact position of its elastic biasing Set), it discharges implantation material 160 (as shown in Figure 10 B).
Anchor element 174 may include plastic material and/or metal material (for example, Nitinol).
1A-B referring to Fig.1 is the lateral parts perspective view between implantation material and the releasing mechanism of implantation material transportation system, with Concept of the present invention is consistent.The implantation material transportation system 100 of Figure 11 A-B and the device 100 of Fig. 1 and/or mentioned herein any Device 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160.Implantation material 160 includes mesh mechanism 170, and mesh mechanism 170 includes filiform 180 and amplifier section 172, wherein enlarging section Divide on 172 proximal ends (as shown in the figure) for being located in filiform 180 or at least proximal end a part.Device 100 may include axis 110, axis 110 include distal end 112, and at least surrounds a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, is operably attached to controlling mechanism 120 on proximal part, and Its distal portions is releaseably attached to mesh mechanism 170, as described below.Connecting rod 141 is from controlling mechanism 120 towards implantation Object 160 extends.Releasing mechanism 140 further includes the grasping mechanism 147 " on 141 distal portions of connecting rod, compressible (for example, radial Compression) pipe or ring.In the position of connecting rod 141 shown in Figure 11 A, grasp mechanism 147 " radially compressed by axis 110 and Around the filiform of mesh mechanism 170, amplifier section 172 is captured, to capture mesh mechanism 170 and stabilisation implant 160.Axis 110 include recess portion 118, and grasping mechanism 147 " can be resiliently biased so that the retraction of connecting rod 141 is (such as via as described herein Controlling mechanism 120) be radially expanded into grasping mechanism 147 " in recess portion 118, allow amplifier section 172 pass through grasping mechanism 147 ", to discharge implantation material 160 (as shown in Figure 11 B).
In some embodiments, recess portion 118 proximally (for example, to proximal end 111 or the proximal part of at least axis 110) moves It is dynamic, such as when the distal portions 115 of axis 110 include the radial nozzle shape geometry for tightening grasping mechanism 147 ".
2A-B referring to Fig.1 is the lateral parts perspective view between implantation material and the releasing mechanism of implantation material transportation system, with Concept of the present invention is consistent.The implantation material transportation system 100 of Figure 12 A-B and the device 100 of Fig. 1 and/or mentioned herein any Device 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160.Implantation material 160 includes mesh mechanism 170, and mesh mechanism 170 includes filiform 180 and fexible bias pressure anchor element, as schemed institute The pipe 176' shown.Device 100 may include axis 110, and axis 110 includes distal end 112, and at least surrounds a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, is operably attached to controlling mechanism 120 on proximal part, and Its distal portions is releaseably attached to mesh mechanism 170, as described below.Connecting rod 141 is from controlling mechanism 120 towards implantation Object 160 extends.Releasing mechanism 140 further includes the amplifier section 144 on 141 distal portions of connecting rod.Amplifier section 144 is located in In pipe 176', so that pipe 176' frictionally engages axis 110, mesh mechanism 170 and thus stabilisation implant 160 are captured.Some In embodiment, pipe 176' includes construction and layout is prominent in order to improve the one or more that pipe 176' is engaged with axis 110 Part 176a.The retraction (such as via controlling mechanism 120 as described herein) of connecting rod 141 makes amplifier section 144 leave pipe 176' allows pipe 176' to be transformed into the compressive state (as shown in Figure 12 B) of fexible bias pressure, discharges implantation material 160.
3A-B referring to Fig.1 is the partially transparent perspective view between implantation material and the releasing mechanism of implantation material transportation system, with Concept of the present invention is consistent.The implantation material transportation system 100 of Figure 13 A-B and the device 100 of Fig. 1 and/or mentioned herein any Device 100 has similar structure and layout, for example including similar controlling mechanism 120, releasing mechanism 140 and/or implantation material 160.Implantation material 160 includes mesh mechanism 170, and mesh mechanism 170 includes filiform 180, and filiform 180 includes as shown in the figure Ring 171.Device 100 may include axis 110, and axis 110 includes distal end 112, and at least surrounds a part of connecting rod 141.
Releasing mechanism 140 includes connecting rod 141, is operably attached to controlling mechanism 120 on proximal part, and Its distal portions is releaseably attached to mesh mechanism 170, as described below.Connecting rod 141 is from controlling mechanism 120 towards implantation Object 160 extends.Releasing mechanism 140 further includes pivot mechanism, in the grasping mechanism 147 " ' of 141 distal portions of connecting rod.Grasping mechanism 147 " ' include rotatable pin, sell 142'.Connecting rod 141 includes the ring 152 engaged with an end of pin 142', ring 171 and pin The opposed end of 142' engages.In the position of connecting rod 141 shown in Figure 13 A, mechanism 147 " is grasped ' capture mesh mechanism 170 Ring 171, thus stabilisation implant 160.The retraction (such as passing through controlling mechanism 120 as described herein) of connecting rod 141 makes pin 142' rotation, is detached from ring 171 from pin 142', to discharge implantation material 160 (as shown in Figure 13 B).
In some embodiments, grasp mechanism 147 " ' position shown in Figure 13 A (for example, via torsionspring or its Its rotary biasing member) it is biased (for example, fexible bias pressure), it provides and retains strength to capture mesh mechanism 170.141 grams of connecting rod It takes in the reservation strength of release mesh mechanism 170, to discharge implantation material 160.
Referring to Fig.1 4, it is the side sectional view of the axis of medical device, it is consistent with concept of the present invention.Axis 110 includes distal end Part 115, middle section 106 and proximal part 105.In some embodiments, distal portions 115 include than proximal part 105 smaller outer diameters (OD), for example, when middle section 106 outer diameter proximal part 105 outer diameter and distal portions 115 it is outer Between diameter when transition (for example, when outer diameter about 0.014 " to about 0.011 ").In these embodiments, the internal diameter of axis 110 (ID) may include about 0.008 " internal diameter (such as about 0.008 " continuous internal diameter or including about 0.008 " internal diameter one A or multiple portions different inner diameters).Equally in these embodiments, distal portions 115 may include the length of about 125mm Degree, middle section 106 may include about 200mm length and/or proximal part 105 may include about 1175mm length Degree.In some embodiments, axis 110 reduces the outer diameter of distal portions 115 by grinding or in other ways (such as to continuous Reduced outer diameter) and the outer diameter (such as to tapered major diameter) of middle section 106 manufacture, such as pass through coreless grinding technology (example As used about 0.014 " outer diameter to carry out " beginning " diameter).
Referring to Fig.1 5, it is the spring ring perspective view of implantation material, it is consistent with concept of the present invention.In some embodiments, The implantation material 160 conceived according to the present invention include spring ring 161 with complex shape, such as Figure 15 spring ring 161 it is circuitous Back-shaped shape.
Referring to Fig.1 6, it is the spring ring perspective view of implantation material, it is consistent with concept of the present invention.In some embodiments, The implantation material 160 conceived according to the present invention includes the spring ring 161 with winding form, for example, Figure 16 spring ring 161 volume Around shape.
In some embodiments, implantation material 160 includes one or more spring rings, and spring ring includes one or more shapes Shape, such as implantation material 160 include one or more bullets of detour shape and winding form as shown in figure 16 as shown in figure 15 Spring coil.
Foregoing description and drawings propose multiple examples of current representative embodiment.According to aforementioned religion It leads, does not depart from spirit of the invention or beyond in the case where its range, to those skilled in the art, various modifications add Adduction alternate design will be apparent, the right of statement as follows non-front various descriptions instruction.It is all and this state it is equal Change and variation in meaning and scope are included in the range of this statement.

Claims (29)

1. a kind of implantation material transportation system (100) characterized by comprising
Implantation material (160) with mesh mechanism (170);
A kind of releasing mechanism (140) comprising the connecting rod (141) with distal portions, the releasing mechanism are attached to the plant Enter the mesh mechanism of object;And
A kind of controlling mechanism (120), constructing and be laid out in the manipulation releasing mechanism makes the releasing mechanism be detached from the plant Enter object;
One elongated shaft (110) at least surrounds a part of connecting rod (141), and the elongated shaft (110) contains proximal end (111), Distal portions (115) and distal end (112);
Connecting rod (141) proximal part is connected to controlling mechanism (120), and the connecting rod (141) distal portions are released Mesh mechanism (170) are connected to property, the releasing mechanism (140) includes bolt (142), and the bolt (142) is fixedly attached to carefully Long axis (110) is located at the distal end outside elongated shaft (110) chamber, and withs a hook at the end between bolt (142) and the distal end of elongated shaft (110) Opening;The ring (171) of the mesh mechanism is from distally proximally extension winding bolt (142), and connecting rod (141) is proximally to remote End extends through ring (171), so that ring (171) is captured by the interface between connecting rod (141) and bolt (142), consolidates implantation material (160), the connecting rod (141) passes through controlling mechanism (120) retraction release ring (171) and implantation material (160).
2. implantation material transportation system according to claim 1, which is characterized in that the elongated shaft (110) includes knit unit Point.
3. implantation material transportation system according to claim 2, which is characterized in that the knitted parts include having about The single line of 0.0015 inch outer diameter.
4. implantation material transportation system according to claim 2, which is characterized in that the knitted parts include that outer diameter exists Multi cord between 0.00125 inch and 0.0015 inch.
5. implantation material transportation system according to claim 2, which is characterized in that the knitted parts are reserved close to described thin The spacing of reduction when the distal end of long axis (110).
6. implantation material transportation system according to claim 1, which is characterized in that elongated shaft (110) construction and layout At frictionally engaging the connecting rod (141).
7. implantation material transportation system according to claim 1, which is characterized in that the elongated shaft (110) is described including accounting for The outer tube of axis at least part position.
8. implantation material transportation system according to claim 1, which is characterized in that at least one of the elongated shaft (110) It is divided into tapered major diameter.
9. implantation material transportation system according to claim 8, which is characterized in that the elongated shaft (110) includes first The proximal part of outer diameter, the axis distal portions include the second external diameter less than the first external diameter, and from first external diameter To the middle section of the various outer diameter of second external diameter transition.
10. implantation material transportation system according to claim 9, which is characterized in that the first external diameter is about 0.014 English Very little, the second external diameter is about 0.011 inch.
11. implantation material transportation system according to claim 1, which is characterized in that further include being located at the connecting rod distal portion Amplifier section on point.
12. implantation material transportation system according to claim 1, which is characterized in that the implantation material is resilient compression shape.
13. implantation material transportation system according to claim 1, which is characterized in that the implantation material includes at least one silk Shape object.
14. implantation material transportation system according to claim 13, which is characterized in that the implantation material includes at least two silks Shape object.
15. implantation material transportation system according to claim 13, which is characterized in that at least one filiform includes bullet Property filiform.
16. implantation material transportation system according to claim 13, which is characterized in that at least one filiform is in pressure Contracting state is the translatable part of the implantation material to be maintained in the hollow space of the implantation material.
17. implantation material transportation system according to claim 1, which is characterized in that the implantation material includes at least one bullet Spring coil.
18. implantation material transportation system according to claim 17, which is characterized in that the implantation material includes the first spring ring With second spring circle.
19. implantation material transportation system according to claim 18, which is characterized in that first spring ring and described second Spring ring includes different diameter.
20. implantation material transportation system according to claim 18, which is characterized in that first spring ring and described second Spring ring is wound in same direction.
21. implantation material transportation system according to claim 18, which is characterized in that first spring ring and described second Spring ring is wound in different directions.
22. implantation material transportation system according to claim 18, which is characterized in that first spring ring is soldered to institute State second spring circle.
23. implantation material transportation system according to claim 1, which is characterized in that the implantation material includes on its distal end Rounded tip ball portion.
24. implantation material transportation system according to claim 1, which is characterized in that the mesh mechanism includes releasing with described Put the enlarged of mechanism release property engagement.
25. implantation material transportation system according to claim 1, which is characterized in that the ring of the mesh mechanism has filiform Object, the ring of the mesh mechanism are releasably engaged with the releasing mechanism.
26. implantation material transportation system according to claim 25, which is characterized in that the ring of the mesh mechanism is attached to Two filiforms, second filiform are in elastic compression so that the ring to be drawn to the hollow space to the implantation material.
27. implantation material transportation system according to claim 25, which is characterized in that the ring of the mesh mechanism includes NiTi Alloy.
28. implantation material transportation system according to claim 27, which is characterized in that the diameter of the mesh mechanism ring is about 0.001 inch.
29. implantation material transportation system according to claim 1, which is characterized in that further include visual marker object.
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CN207708054U (en) 2018-08-10
CN207721935U (en) 2018-08-14
CN106943218A (en) 2017-07-14
CN207721934U (en) 2018-08-14
CN110859691A (en) 2020-03-06
CN110859693B (en) 2022-03-18
CN110859692B (en) 2021-11-23
CN110859693A (en) 2020-03-06
CN207590809U (en) 2018-07-10
CN110859691B (en) 2021-11-23
CN207590810U (en) 2018-07-10
CN110801259A (en) 2020-02-18

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