CN106943134A - A kind of wearable blood pressure regulation device - Google Patents
A kind of wearable blood pressure regulation device Download PDFInfo
- Publication number
- CN106943134A CN106943134A CN201710154602.6A CN201710154602A CN106943134A CN 106943134 A CN106943134 A CN 106943134A CN 201710154602 A CN201710154602 A CN 201710154602A CN 106943134 A CN106943134 A CN 106943134A
- Authority
- CN
- China
- Prior art keywords
- blood pressure
- wearable
- microneedles
- wearable blood
- pressure regulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6802—Sensor mounted on worn items
- A61B5/681—Wristwatch-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2209/00—Ancillary equipment
- A61M2209/08—Supports for equipment
- A61M2209/088—Supports for equipment on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/04—Skin
Abstract
The invention belongs to hypertension regulation and control product technical field, more particularly to a kind of wearable blood pressure regulation device, including wearable blood pressure supervising device and micropin formula blood pressure doser, the micropin formula blood pressure doser includes Wearable bracelet, the microneedle drug device being installed on Wearable bracelet, and be installed on Wearable bracelet for starting spring assembly of the microneedle drug device to human administration, spring assembly can start microneedle drug device and be administered when the pressure value of the wearable blood pressure supervising device monitoring is beyond the value range of setting.The regulating blood pressure apparatus structure is simple, it is easy to use, can immediately it be administered according to the abnormal conditions of blood pressure while blood pressure is monitored, to accomplish timely and effectively to adjust blood pressure, blood pressure is allowed to be maintained at stability number, it is ensured that hypertension or low blood pressure patient's is healthy.
Description
Technical field
The invention belongs to hypertension regulation and control product technical field, more particularly to a kind of wearable blood pressure regulation device.
Background technology
The pressure value of people is natively in fluctuation status, is referred to as hypertension or low blood higher or lower than normotensive value
Pressure, pressure value suddenly will cause irreversible infringement, this situation higher or lower than range of normal value to the health of the mankind
Health hazard to the elderly is particularly evident, and because blood vessel accumulates fat with the age and hardens, elasticity is poor compared with young man, it is easier to
By temperature and emotion influence, cause blood pressure suddenly to rise and fall, trigger acute cerebral stroke, cause cerebral ischemic and hemorrhagic to damage
Wound.
Hypertension is again the substantial risk factor of the diseases such as heart disease, apoplexy, kidney trouble, eye illness, if control for a long time it is bad,
System vascular and organ have lesion risk, and thing followed disease has obstruction of artery, coronary disease disease, eye ground lesion, kidney
Dirty exhaustion etc.；Relative to hypertension, low blood pressure is almost without sign, and acute hypotension refers to blood pressure by Zheng Chang More high levels suddenly
Usually people just falls in a swoon, fainted between several seconds for decline, or even shock, and causing to fall causes the generation of fracture, meanwhile, human brain
Blood supply with heart is not enough, the organ lesions such as angiocarpy is caused, so abnormal in the unstable or short time of pressure value
It is higher or relatively low serious threat can be all caused to the health of human body.
Wherein hypertension is a kind of chronic disease again, thoroughly effects a radical cure that this disease is very difficult, and current medical science is for hypertension
The common processing method of disease is to make blood pressure long-term in normal range (NR) using medicine control, effective preventing hypertension complication.
Most common step-down mode is to take oral administration, and oral drug therapy can reach that control blood pressure reaches normal level mostly,
But cause the factor of dysarteriotony more, and such as mood, weather, physical efficiency liveness, single oral administration is inadequate, it is necessary to
Complex treatment is taken, preferable pressure control effect is otherwise unable to reach.
Hyperpietic is significantly raised in the blood pressure short time in disease progression or under the effect of some inducements, this
Hypertension emergency patient's condition is swift and violent, the emergency time typically given only about 10 minutes, if emergency measures is ineffective, patient holds very much
It is easily dead in a short time.For hypertension emergency, generally require award in time intravenous administration just can be in time
Blood pressure is controlled in normal range (NR).
For having the patient of dysarteriotony medical history above all real-time and correctly monitoring blood pressure, the long-term of blood pressure is grasped
Fluctuation, required pressure control dose is given exactly to control blood pressure perfectly.The electronic sphygmomanometer person of needing to use on the market determines
When voluntarily measure blood pressure, it is impossible to grasp the fluctuation situation of actually blood pressure.
And the wearable device updated measures blood pressure using pressure sensor and vibrating sensor, this provides monitoring
Function, does not possess administration and the function of control blood pressure, and still can not deal with blood pressure is raised and lowered burst ofly.Therefore monitor
It is very important equipment to the patient of dysarteriotony that the wearable device of blood pressure has timely administration functions simultaneously, just as carry-on
First-aid kit is general.
Existing blood pressure facilitates residential use in respect of mercurial sphygmomanometer and electronic sphygmomanometer, electronic sphygmomanometer, in measurement blood
During air pressure declines in the cuff of pressure, it may appear that a wave of oscillation, when amplitude of oscillation reaches maximum, corresponding is average outer
Pressure can be considered the average blood pressure of the measured, then set up conversion method mathematically, to extrapolate pressure value, such a blood
Pressure meter can only provide Timing measurement, it is impossible to meet the requirement of monitoring blood pressure in real time, then there is pushing away for wearable blood pressure supervising device
User is out realized at any time in the state of blood pressure monitoring, but this remains unchanged not for determining the patient of medical history with unstable blood pressure
It can guarantee that and can obtain emergency treatment at any time when acute disease occurs, because wearable blood pressure monitoring device is without administration in time or adjusts
Save the function of blood pressure.
The general patient with unstable blood pressure can carry with the oral medicine of control blood pressure, according to different antihypertensive drugs
Generally requiring 15-30 minutes to work, half-life period have 3-4 hours, what is had will also grow, and deal with hypertension emergency or
The medicine of low blood pressure acute disease, such as blood-pressure drug nitroglycerin or sodium nitroprussiate, or hypertensive agent thing dopamine and catechu
The medicines such as phenol amine drug are also required to about 5-10 minutes to work, real from finding that patients' blood is abnormal to first aid medication is given
Most people all has little time to react and miss the time of gold first aid 10 minutes on border.
For hypertension emergency patient, short-acting intravenous pharmacy method can be typically taken to come first aid, such as blood-pressure drug nitric acid
Glycerine or sodium nitroprussiate, or hypertensive agent thing dopamine and Catecholamine drugs etc., the quick and stable within short a few minutes
Blood pressure, in order to avoid cause heart and brain kidney organ's lesion.This is in hospital or having available under conditions of paramedic
First aid, but it is that can not voluntarily do vein note that precipitate blood pressure rising or drop in blood pressure occur outside or at home for common people
Short-acting intravenous pharmacy is penetrated, even if patient has carried real-time blood pressure monitoring device, is also unable to cope with needed for abnormal blood pressure acute disease
Timely intravenously administrable.An equipment is there is no now possesses monitoring blood pressure also while being administered immediately when finding dysarteriotony
Function.
Therefore, research and develop it is a kind of when can also find dysarteriotony while possess monitoring blood pressure can administration functions immediately blood pressure
Regulation device is extremely urgent.
The content of the invention
The purpose of the present invention is to overcome the deficiencies in the prior art, discloses a kind of wearable blood pressure regulation device, and the blood pressure is adjusted
Control apparatus structure simple, it is easy to use, can immediately it be administered according to the abnormal conditions of blood pressure while blood pressure is monitored, to do
To blood pressure is timely and effectively adjusted, blood pressure is allowed to be maintained at stability number, it is ensured that hypertensive patient's is healthy.
In order to reach above-mentioned technical purpose, the present invention is realized by following technical scheme：
A kind of wearable blood pressure regulation device of the present invention, including wearable blood pressure supervising device and micropin formula blood pressure
Doser, the micropin formula blood pressure doser includes Wearable bracelet, the microneedle drug being installed on Wearable bracelet dress
Put, and be installed on Wearable bracelet for starting spring assembly of the microneedle drug device to human administration, the Wearable
Spring assembly can start microneedle drug device and be administered when the pressure value of blood pressure supervising device monitoring is beyond the value range of setting.
As the further improvement of above-mentioned technology, the microneedle drug device is some microneedle patch and is fixed on microneedle patch
Microneedles on piece, the microneedles are made by hypertension drug.
Specifically, the constituent material of the microneedles includes polysaccharide, or macromolecular material such as CMC, or PVP, or
PVA/PVP, or metal or inorganic material, or fibroin, or chondroitin sulfate, or Sodium Hyaluronate biocompatibility are high simultaneously
At least one of biodegradable material, or two or more any material are constituted；Wherein doping controls the medicine of blood pressure
It is calcium-channel antagonists or RAS system blocking agent, or diuretics, or receptor blocking agent that thing, which includes hypotensor, or α 1- by
Body blocking agent, or nitroglycerin, or nitre paving sodium, or hypertensive agent thing such as dopamine and Catecholamine drugs at least one
Kind, or two or more any medicine.
In the present invention, in order to preferably accomplish the security of administration, hypertension agents dose range in the microneedles
In 0.1-50mg.
In the present invention, the length of the microneedles is not more than 1cm, and the microneedles can insert brokenly skin surface, but its
Subcutaneous nerve will not be touched, therefore pain will not be caused.
In the present invention, the microneedles are solid construction or solid construction, and the micropin of hollow-core construction can carry out persistently may be used
The administration of control.
In the present invention, spring assembly meeting when the pressure value of the wearable blood pressure supervising device monitoring exceedes certain limit
The Starting mode for starting microneedle drug device is manual mode or automated manner, and Starting mode is simple and convenient, it is easy to accomplish.
In the present invention, the wearable blood pressure supervising device to spring assembly transmission start signal mode be wired or nothing
Line transmission means, radio transmitting method includes but is not limited to Wifi or bluetooth or low-power consumption bluetooth or zigbee or RFID.
In the present invention, the microneedle patch is one chip or is that single can be provided with multiple-piece, multiple-piece microneedle patch
Or the microneedles of a variety of pressure control medicines.
Compared with prior art, the beneficial effects of the invention are as follows：
Regulating blood pressure device of the present invention, it dexterously combines Wearable hypertension supervising device and micropin formula blood
Press doser, when monitor pressure value beyond setting value range when spring assembly can start microneedle drug device to
Medicine, responds according to blood pressure situation in real time, subcutaneous medicament injection release is painlessly carried out using microneedles, regulation and control are abnormal in time
Blood pressure conditions, allow blood pressure to be maintained at stability number, regulation blood pressure is timely and effective.
Brief description of the drawings
The present invention is described in detail with specific embodiment below in conjunction with the accompanying drawings：
Fig. 1 is wearable blood pressure regulation device structural representation of the present invention.
Fig. 2 is that wearable blood pressure regulation device of the present invention uses schematic flow sheet.
Embodiment
As shown in Figure 1 and Figure 2, a kind of wearable blood pressure regulation device of the present invention, including wearable blood pressure monitoring dress
Put 10 and micropin formula blood pressure doser 20, the wearable forearm or upper arm in people of Wearable hypertension supervising device 10,
The micropin formula blood pressure doser 20 includes Wearable bracelet 21, the microneedle drug device being installed on Wearable bracelet 21
22, and be installed on Wearable bracelet 21 for starting spring assembly 23 of the microneedle drug device 22 to human administration, it is described
Spring assembly 23 can start microneedle drug dress when the pressure value that wearable blood pressure supervising device 10 is monitored is beyond the value range of setting
22 are put to be administered.
As shown in Fig. 2 the microneedle drug device 22 is some microneedle patch 221 and is fixed in microneedle patch 221
Microneedles 222, the microneedle patch 221 is placed in the inside of Wearable bracelet 21, and typically the used time is not put into Wearable bracelet 21
To protect microneedle patch 221, during startup, microneedle patch 221 can be automatically opened up for inside exposes microneedle patch after microneedles 222, startup
Piece 221 is pressed close to skin, and microneedle patch 221 and microneedles 222 insert skin surface under the promotion of spring assembly 23 and then released
Put pressure control medicine.
In the present invention, the microneedles 222 are made by hypertension drug, specifically, the microneedles 222
Constituent material includes polysaccharide, or macromolecular material such as CMC, or PVP, or PVA/PVP, or metal or inorganic material, or silkworm
Silk-fibroin, or chondroitin sulfate, or high simultaneously at least one of the biodegradable material of Sodium Hyaluronate biocompatibility, or appoint
Anticipate two or more material composition；Wherein doping control the medicine of blood pressure include hypotensor for calcium-channel antagonists or
RAS system blocking agent, or diuretics, or receptor blocking agent, or alpha 1-receptor blocking agent, or nitroglycerin, or nitre paving sodium, or
Person's hypertensive agent thing such as dopamine and Catecholamine drugs are at least one, or two or more any medicine.
In addition, the dosage range of hypertension drug exists in the security in order to preferably accomplish administration, the microneedles 222
0.1-50mg, and the length of the microneedles 222 is not more than 1cm, the microneedles 222 can insert brokenly skin surface, but it is not
Subcutaneous nerve can be touched, therefore pain will not be caused；The microneedles 222 are solid construction or solid construction, hollow knot
The micropin of structure can carry out persistently controllable administration.The microneedle patch 221 is one chip or is multiple-piece, multiple-piece microneedle patch
On can the microneedles provided with single or a variety of pressure control medicines
In the present invention, the spring assembly when pressure value that the wearable blood pressure supervising device 10 is monitored exceedes certain limit
23 Starting mode that can start microneedle drug device 20 are manual mode or automated manner, and Starting mode is simple and convenient, it is easy to real
It is existing.
In the present invention, the wearable blood pressure supervising device 10 is wired to the transmission start signal mode of spring assembly 23
Or wireless transmission method, radio transmitting method includes but is not limited to Wifi or bluetooth or low-power consumption bluetooth or zigbee or RFID.
Regulation and control rank below by way of two instantiations is explained：
Embodiment 1
Wearable blood pressure supervising device 10 can be according to blood pressure Classification come early warning, and 3 grades as follows：
Slight (1 grade of hypertension) 90~99mmHg of 140~159mmHg of systolic pressure or diastolic pressure；
Moderate (2 grades of hypertension) 100~110mmHg of 160~179mmHg of systolic pressure or diastolic pressure；
Severe (3 grades of hypertension) systolic pressure is more than 180mmHg or diastolic pressure more than 110mmHg.
An early warning is given when slight；2 early warning are given during moderate plus manually booting selection；Severe gives 3 alarms
Automatic microneedle patch 221 and microneedles 222, every 2 minutes afterwards report pressure values, until blood pressure keeps stable.
Embodiment 2
During hypotensive episode, wearable blood pressure monitoring device 10 detects pressure value and is consistently less than 80mmHg, slightly gives
One early warning, moderate gives 2 early warning plus selection is manually booted, and severe gives 3 Hes of alarm automatic microneedle patch 221
Microneedles 222, every 2 minutes afterwards report pressure values, until blood pressure keeps stable.
The present invention can be responded according to blood pressure situation in real time, and subcutaneous medicament injection release is painlessly carried out using micropin,
The abnormal blood pressure conditions of regulation and control, allow blood pressure to be maintained at stability number in time, it is ensured that hypertension sufferer it is healthy.
The invention is not limited in above-mentioned embodiment, every various changes or modification to the present invention do not depart from the present invention
Spirit and scope, if these are changed and modification belongs within the scope of the claim and equivalent technologies of the present invention, then this hair
It is bright to also imply that comprising these changes and modification.
Claims (10)
1. a kind of wearable blood pressure regulation device, it is characterised in that：Given including wearable blood pressure supervising device and micropin formula blood pressure
Medicine device, the micropin formula blood pressure doser includes Wearable bracelet, the microneedle drug device being installed on Wearable bracelet,
And be installed on Wearable bracelet for starting spring assembly of the microneedle drug device to human administration, the wearable blood pressure
Spring assembly can start microneedle drug device and be administered when the pressure value of supervising device monitoring is beyond the value range of setting.
2. wearable blood pressure regulation device according to claim 1, it is characterised in that：The microneedle drug device is some
Microneedle patch and the microneedles being fixed in microneedle patch, the microneedles are made by hypertension drug.
3. wearable blood pressure regulation device according to claim 2, it is characterised in that：The constituent material bag of the microneedles
Include polysaccharide, or macromolecular material such as CMC, or PVP, or PVA/PVP, or metal or inorganic material, or fibroin, or sulphur
Aching and limp ossein, or high simultaneously at least one of the biodegradable material, or any two kinds or two of Sodium Hyaluronate biocompatibility
Above material is planted to constitute；It is calcium-channel antagonists or RAS system blockings that wherein doping, which controls the medicine of blood pressure to include hypotensor,
Agent, or diuretics, or receptor blocking agent, or alpha 1-receptor blocking agent, or nitroglycerin, or nitre paving sodium, or hypertensive agent thing
Such as dopamine and Catecholamine drugs are at least one, or two or more any medicine.
4. wearable blood pressure regulation device according to claim 3, it is characterised in that：Hypertension drug in the microneedles
Dosage range is in 0.1-50mg.
5. wearable blood pressure regulation device according to claim 2, it is characterised in that：The length of the microneedles is not more than
1cm。
6. the wearable blood pressure regulation device according to any one of claim 2 to 5, it is characterised in that：The microneedles are
Solid construction or solid construction, the micropin of hollow-core construction can carry out persistently controllable administration.
7. wearable blood pressure regulation device according to claim 1, it is characterised in that：The wearable blood pressure supervising device
When the pressure value of monitoring exceedes certain limit spring assembly can start the Starting mode of microneedle drug device for manual mode or from
Flowing mode.
8. wearable blood pressure regulation device according to claim 6, it is characterised in that：The wearable blood pressure supervising device
To spring assembly transmission start signal mode be wired or wireless transmission means, radio transmitting method include but is not limited to Wifi or
Bluetooth or low-power consumption bluetooth or zigbee or RFID.
9. wearable blood pressure regulation device according to claim 2, it is characterised in that：The microneedle patch is one chip.
10. wearable blood pressure regulation device according to claim 2, it is characterised in that：The microneedle patch is multiple-piece,
The microneedles of single or a variety of pressure control medicines can be provided with multiple-piece microneedle patch.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710154602.6A CN106943134A (en) | 2017-03-15 | 2017-03-15 | A kind of wearable blood pressure regulation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710154602.6A CN106943134A (en) | 2017-03-15 | 2017-03-15 | A kind of wearable blood pressure regulation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106943134A true CN106943134A (en) | 2017-07-14 |
Family
ID=59472103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710154602.6A Pending CN106943134A (en) | 2017-03-15 | 2017-03-15 | A kind of wearable blood pressure regulation device |
Country Status (1)
| Country | Link |
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| CN (1) | CN106943134A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107669251A (en) * | 2017-11-08 | 2018-02-09 | 何庆 | A kind of heartbeat monitoring of respiration method and monitoring bracelet |
| CN108310615A (en) * | 2017-12-29 | 2018-07-24 | 浙江理工大学 | A kind of microneedle cutaneous device of photoinduction |
| CN108671383A (en) * | 2018-06-01 | 2018-10-19 | 陶军 | The real-time diagnosis and treatment integral system of hypertension of wearable controlled drug release |
| CN110584633A (en) * | 2019-09-06 | 2019-12-20 | 湘南学院附属医院 | Hypertension real-time diagnosis and treatment integrated system capable of controlling drug release |
| CN112806981A (en) * | 2021-02-05 | 2021-05-18 | 北京大学口腔医学院 | Knee joint health management fitness trousers |
| CN112870543A (en) * | 2021-02-26 | 2021-06-01 | 中山大学 | Drug release control device, control method thereof, and computer-readable storage medium |
| CN114081455A (en) * | 2021-10-10 | 2022-02-25 | 湖南云医链生物科技有限公司 | Traditional chinese medical science pulse-taking intelligence health management wrist-watch |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101972499A (en) * | 2010-11-10 | 2011-02-16 | 吉林大学 | Easy painless drug delivery device |
| US20110177139A1 (en) * | 2008-10-01 | 2011-07-21 | Nurim Wellness Co. Ltd. | Solid microstructure that enables multiple controlled release and method of maufacturing same |
| US20150201880A1 (en) * | 2012-07-10 | 2015-07-23 | Becton Dickinson France S.A.S. | Integrated Injection System and Communication Device |
| CN105246458A (en) * | 2013-03-15 | 2016-01-13 | 考里安国际公司 | Microarray for delivery of therapeutic agent and methods of use |
| US20170000416A1 (en) * | 2015-07-01 | 2017-01-05 | i-calQ, LLC | Point of wear device |
-
2017
- 2017-03-15 CN CN201710154602.6A patent/CN106943134A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110177139A1 (en) * | 2008-10-01 | 2011-07-21 | Nurim Wellness Co. Ltd. | Solid microstructure that enables multiple controlled release and method of maufacturing same |
| CN101972499A (en) * | 2010-11-10 | 2011-02-16 | 吉林大学 | Easy painless drug delivery device |
| US20150201880A1 (en) * | 2012-07-10 | 2015-07-23 | Becton Dickinson France S.A.S. | Integrated Injection System and Communication Device |
| CN105246458A (en) * | 2013-03-15 | 2016-01-13 | 考里安国际公司 | Microarray for delivery of therapeutic agent and methods of use |
| US20170000416A1 (en) * | 2015-07-01 | 2017-01-05 | i-calQ, LLC | Point of wear device |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107669251A (en) * | 2017-11-08 | 2018-02-09 | 何庆 | A kind of heartbeat monitoring of respiration method and monitoring bracelet |
| CN108310615A (en) * | 2017-12-29 | 2018-07-24 | 浙江理工大学 | A kind of microneedle cutaneous device of photoinduction |
| CN108671383A (en) * | 2018-06-01 | 2018-10-19 | 陶军 | The real-time diagnosis and treatment integral system of hypertension of wearable controlled drug release |
| CN108671383B (en) * | 2018-06-01 | 2023-08-11 | 中山大学附属第一医院 | Wearable hypertension real-time diagnosis and treatment integrated system capable of controlling drug release |
| CN110584633A (en) * | 2019-09-06 | 2019-12-20 | 湘南学院附属医院 | Hypertension real-time diagnosis and treatment integrated system capable of controlling drug release |
| CN112806981A (en) * | 2021-02-05 | 2021-05-18 | 北京大学口腔医学院 | Knee joint health management fitness trousers |
| CN112806981B (en) * | 2021-02-05 | 2022-03-25 | 北京大学口腔医学院 | Knee joint health management fitness trousers |
| CN112870543A (en) * | 2021-02-26 | 2021-06-01 | 中山大学 | Drug release control device, control method thereof, and computer-readable storage medium |
| CN112870543B (en) * | 2021-02-26 | 2022-06-21 | 中山大学 | Drug release control device, control method thereof, and computer-readable storage medium |
| CN114081455A (en) * | 2021-10-10 | 2022-02-25 | 湖南云医链生物科技有限公司 | Traditional chinese medical science pulse-taking intelligence health management wrist-watch |
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