CN106880814A - 一种用于治疗类风湿关节炎的中药组合物及其制备方法 - Google Patents
一种用于治疗类风湿关节炎的中药组合物及其制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医对类风湿性关节炎的认识机理而提供的一种用于治疗类风湿关节炎的中药组合物,所述中药组合物的各个组分及其质量份比如下:黄芪150~360g、桂枝30~120g、白芍50~150g、清风藤100~160g、知母60~150g、麻黄15~100g、姜黄50~160g、生地黄100~160g、丹参80~160g、白芷30~100g、南蛇藤150~260g、淫羊藿50~160g、鸡血藤150~260g、泽泻60~120g;本发明提供的药物是一个标本兼治的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种用于治疗类风湿关节炎的中药组合物,特别是供类风湿关节炎患者使用的中药组合物及其制备方法的领域。
背景技术
据文献显示:类风湿关节炎是一种以关节滑膜炎症为主的全身性疾病,发病早期往往有全身症状,如发热、疲劳、饮食不振、周身不适等,严重者可同时伴有贫血,临床症状:双手指,双脚趾,腕,踝等小关节首先发病,晨间出现关节僵硬,化验类风湿因子(RF) 呈阳性;到中晚期,关节肿痛增剧,肿处较硬,晨僵时间延长,关节逐渐累及肘、肩、膝、髋等大关节,严重者出现关节半脱位和畸形,病人活动受限,生活多难以自理。
那么,就如何找到一种可有效治疗类风湿关节炎的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗类风湿关节炎上,人们逐渐意识到了中医治疗类风湿关节炎的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗类风湿关节炎的现状,本发明的目的是在于提供一种用于治疗类风湿关节炎的中药组合物,以解决类风湿关节炎患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述类风湿关节炎。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种用于治疗类风湿关节炎的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪150~360g、桂枝30~120g、白芍50~150g、清风藤100~160g、知母60~150g、麻黄15~100g、姜黄50~160g、生地黄100~160g、丹参80~160g、白芷30~100g、南蛇藤150~260g、淫羊藿50~160g、鸡血藤150~260g、泽泻60~120g。
一种用于治疗类风湿关节炎的中药组合物及其制备方法,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪170~320g、桂枝40~105g、白芍60~130g、清风藤115~140g、知母70~130g、麻黄20~95g、姜黄60~140g、生地黄115~140g、丹参90~140g、白芷40~90g、南蛇藤170~230g、淫羊藿60~140g、鸡血藤170~230g、泽泻70~105g。
一种用于治疗类风湿关节炎的中药组合物及其制备方法,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
黄芪280g、桂枝95g、白芍115g、清风藤120g、知母115g、麻黄85g、姜黄120g、生地黄120g、丹参120g、白芷80g、南蛇藤200g、淫羊藿120g、鸡血藤200g、泽泻95g。
一种用于治疗类风湿关节炎的中药组合物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药胶囊剂的方法,将研磨好的极细末药物过筛后,放入药器中混合均匀,然后制备成胶囊剂(其胶囊锁合后总长度为23.3mm,药粉容量0.4~0.5g/粒),分装密封即可。
一种用于治疗类风湿关节炎的中药组合物及其制备方法,其特征在于,所述服用方法为:将制备好的胶囊剂药物以每日二次服用,早晚各服一次,给药量2.5g(5粒)/次,饭后服。16天为一个疗程,服药1~2个疗程,症状消失,病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
黄芪,性味:甘、微温,具有补气固表、利尿托毒、排脓、敛疮生肌之功效,用于治疗气虚乏力、食少便溏、中气下陷、久泻脱肛、便血崩漏、表虚自汗、气虚水肿、痈疽难溃、久溃不敛、血虚痿黄、内热消渴、慢性肾炎蛋白尿、糖尿病;
桂枝,性味:辛、甘、性温,具有散寒解表、温通经脉、通阳化气之功效,用于治疗风寒表证、寒湿痹痛、四肢厥冷、经闭痛经、症瘕结块、胸痹、心悸、痰饮、小便不利;
白芍,性味:苦、酸、微寒,具有养血和营;缓急止痛;敛阴平肝之功效,用于治疗***、经行腹痛、崩漏、自汗、盗汗胁肋脘腹疼痛、四肢挛痛、头痛、眩晕;
清风藤,性味:苦、辛、温,具有祛风利湿、活血解毒之功效,用于治疗风湿痹痛、鹤膝风、水肿、脚气、跌打肿痛、骨折、深部脓肿、骨髓炎、化脓性关节炎、脊椎炎、疮疡肿毒、皮肤瘙痒;
知母,性味:味苦、性寒,具有清热泻火、滋阴润燥、止渴除烦之功效,用于治疗温热病、高热烦渴、咳嗽气喘、燥咳、便秘、骨蒸潮热、虚烦不眠、消渴淋浊;
麻黄,性味:辛、微苦、性温,具有发汗解表、宣肺平喘、利水消肿之功效,用于治疗风寒表实证、恶寒发热、无汗、头痛身疼、邪壅于肺、肺气不宣、咳嗽气喘、风水肿、小便不利、风湿痹痛、肌肤不仁以及风疹瘙痒、阴疽痰核;
姜黄,性味:辛苦、温,具有破血、行气、通经、止痛之功效,用于治疗心腹痞满胀痛、臂痛、症瘕、妇女血瘀经闭、产后瘀停腹痛、跌扑损伤、痈肿等症;
生地黄,性味:甘、寒,具有清热凉血、养阴、生津之功效,用于治疗热病舌绛烦渴、阴虚内热、骨蒸劳热、内热消渴、吐血、衄血、发斑发疹;
丹参,性味:味苦、性微寒,具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效,用于治疗妇女***、痛经、经闭、产后瘀滞腹痛、心腹疼痛、症瘕积聚、热痹肿痛、跌打损伤、热入营血、烦躁不安、心烦失眠、痈疮肿毒;
白芷,性味:味辛、性温,具有祛风除湿、通窃止痛、消肿排脓之功效,用于治疗感冒头痛、眉棱骨痛、牙痛、鼻塞、鼻渊、湿胜久泻、妇女白带、痈疽疮疡、毒蛇咬伤;
南蛇藤,性味:辛、温,具有祛风活血、消肿止痛之功效,用于治疗风湿关节炎、跌打损伤、腰腿痛、闭经;
淫羊藿,性味:辛甘、温,具有补肾壮阳、祛风除湿之功效,用于治疗阳痿不举、小便淋沥、筋骨挛急、半身不遂、腰膝无力、风湿痹痛、四肢不仁;
鸡血藤,性味:苦甘、温,具有活血、舒筋之功效,用于治疗腰膝酸痛、麻木瘫痪、***;
泽泻,性味:甘、寒,具有利小便、清湿热之功效,用于治疗小便不利、水肿胀满、泄泻尿少、痰饮眩晕、热淋涩痛、高血脂。
本发明药物是基于中医治疗类风湿关节炎的原则,从药理作用及作用机制认为:就类风湿关节炎,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述类风湿关节炎的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种用于治疗类风湿关节炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪280g、桂枝95g、白芍115g、清风藤120g、知母115g、麻黄85g、姜黄120g、生地黄120g、丹参120g、白芷80g、南蛇藤200g、淫羊藿120g、鸡血藤200g、泽泻95g。
实施例2:
一种用于治疗类风湿关节炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪320g、桂枝105g、白芍130g、清风藤140g、知母130g、麻黄95g、姜黄140g、生地黄140g、丹参140g、白芷90g、南蛇藤230g、淫羊藿140g、鸡血藤230g、泽泻105g。
实施例3:
一种用于治疗类风湿关节炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪360g、桂枝120g、白芍150g、清风藤160g、知母150g、麻黄100g、姜黄160g、生地黄160g、丹参160g、白芷100g、南蛇藤260g、淫羊藿160g、鸡血藤260g、泽泻120g。
典型病例
经临床诊断治疗类风湿关节炎患者共790例,年龄为57岁以上的496例,只有294例为57岁以下。790例患者中痊愈的635例,有效的155例,总有效率达100%。
Claims (3)
1.一种用于治疗类风湿关节炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪150~360g、桂枝30~120g、白芍50~150g、清风藤100~160g、知母60~150g、麻黄15~100g、姜黄50~160g、生地黄100~160g、丹参80~160g、白芷30~100g、南蛇藤150~260g、淫羊藿50~160g、鸡血藤150~260g、泽泻60~120g。
2.根据权利要求1所述的用于治疗类风湿关节炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪170~320g、桂枝40~105g、白芍60~130g、清风藤115~140g、知母70~130g、麻黄20~95g、姜黄60~140g、生地黄115~140g、丹参90~140g、白芷40~90g、南蛇藤170~230g、淫羊藿60~140g、鸡血藤170~230g、泽泻70~105g。
3.根据权利要求1至2所述的用于治疗类风湿关节炎的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
黄芪280g、桂枝95g、白芍115g、清风藤120g、知母115g、麻黄85g、姜黄120g、生地黄120g、丹参120g、白芷80g、南蛇藤200g、淫羊藿120g、鸡血藤200g、泽泻95g。
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