CN106860816A - A kind of Chinese medicine composition for treating depression and preparation method thereof - Google Patents

A kind of Chinese medicine composition for treating depression and preparation method thereof Download PDF

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Publication number
CN106860816A
CN106860816A CN201710182205.XA CN201710182205A CN106860816A CN 106860816 A CN106860816 A CN 106860816A CN 201710182205 A CN201710182205 A CN 201710182205A CN 106860816 A CN106860816 A CN 106860816A
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chinese medicine
medicine composition
depression
treating depression
pinellia
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罗倩茹
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Chengdu Hai Qing Biological Science And Technology Co Ltd
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Chengdu Hai Qing Biological Science And Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods

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Abstract

The invention belongs to technical field of Chinese medicine, it is therefore an objective to which, according to a kind of Chinese medicine composition for treating depression that the traditional Chinese medical science is provided the understanding mechanism of depression, each component and its mass parts ratio of the Chinese medicine composition are as follows：2.5~5g of the coptis, 5~16g of intelligence development, 15~30g of the Radix Astragali, 8~16g of Radix Angelicae Sinensis, 8~16g of the bighead atractylodes rhizome, 6~12g of dried orange peel, 10~20g of Polygonum multiflower knotweed, 15~45g of mother-of-pearl, 15~32g of date, 6~16g of asparagus fern, 3~9g of the tuber of pinellia, 2.5~16g of ginseng；The medicine that the present invention is provided is a Chinese prescription treated both principal and secondary aspect of disease.

Description

A kind of Chinese medicine composition for treating depression and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, and in particular to a kind of Chinese medicine composition for treating depression, especially It is the field of the Chinese medicine composition that is used for patients with depression and preparation method thereof.
Background technology
Doctor thinks：Depression also known as depressive disorder, with notable and lasting mental state it is low be main clinical characteristics, be the heart The main Types of border obstacle.Clinical visible mental state is low unbecoming with its situation, and the downhearted of mood can be from depressed to compassion Bitterly wild, depression of feeling oneself inferior, in addition it is pessimistic and worldweary, can there are conamen or behavior；Even occur numb；Some cases have significantly Anxiety and motility are intense；Severe patient may occur in which the psychotic symptoms such as illusion, vain hope.Every time breaking-out continue at least more than 2 weeks, Even elder's several years, majority of cases has the tendency of recurrent exerbation, breaking-out is most of every time can alleviate, and can partly have residual symptoms Or switch to chronic.
So, a kind of Chinese medicine composition that can effectively treat above-mentioned depression how is just found, is that we are badly in need of wanting at present The problem of solution.
The content of the invention
With continuing to develop for China's traditional Chinese medicine, in treatment depression, people gradually appreciate Chinese traditional treatment The advantage of above-mentioned depression, and toxic and side effect is small over the course for the treatment of, the low advantage of expense, for the above-mentioned suppression of existing western medical treatment The present situation of strongly fragrant disease, it is to provide a kind of Chinese medicine composition for treating depression that the purpose of the present invention is, to solve depression Patient's restorative problem early.The medicine be with common Chinese medicine as raw material, with instant effect, it is evident in efficacy the features such as, And can effectively treat above-mentioned depression.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided a kind of for treating depression Chinese medicine composition and preparation method thereof, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition are as follows It is shown：
2.5~5g of the coptis, 5~16g of intelligence development, 15~30g of the Radix Astragali, 8~16g of Radix Angelicae Sinensis, 8~16g of the bighead atractylodes rhizome, 6~12g of dried orange peel, night hand over 10~20g of rattan, 15~45g of mother-of-pearl, 15~32g of date, 6~16g of asparagus fern, 3~9g of the tuber of pinellia, 2.5~16g of ginseng.
A kind of Chinese medicine composition for treating depression and preparation method thereof, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：
3~4.5g of the coptis, 10~14g of intelligence development, 18~26g of the Radix Astragali, 10~14g of Radix Angelicae Sinensis, 10~14g of the bighead atractylodes rhizome, 8~11g of dried orange peel, night Hand over 12~17g of rattan, 20~40g of mother-of-pearl, 20~28g of date, 10~14g of asparagus fern, 6~8g of the tuber of pinellia, 10~14g of ginseng.
A kind of Chinese medicine composition for treating depression and preparation method thereof, it is characterised in that " preferred plan " Chinese medicine composition each component and its mass parts than as follows：
Coptis 4g, intelligence development 13g, Radix Astragali 23g, Radix Angelicae Sinensis 13g, bighead atractylodes rhizome 13g, dried orange peel 10g, Polygonum multiflower knotweed 15g, mother-of-pearl 35g, date 25g, asparagus fern 14g, tuber of pinellia 7g, ginseng 13g.
A kind of Chinese medicine composition for treating depression and preparation method thereof, it is characterised in that methods described is included such as Lower step is prepared from：
A, above-mentioned raw materials Chinese medicine is picked into impurity and dust after, be ground into superfine end according to mass parts ratio stand-by；
B, the method that Chinese kmedicine bolus agent is prepared according to tradition, after ground superfine myrrh thing is sieved, are put into mixing in medicine device Mix, be then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：4.7mm-5.0mm）, and then dry, sealed packaging.
A kind of Chinese medicine composition for treating depression and preparation method thereof, it is characterised in that the instructions of taking is： The water pill medicine that will be prepared is serviced once sooner or later with twice a day taking, and dosage 2.5g/time, it is before meals（Warm water Send down）, to take medicine 30~90 days, symptom gradually mitigates or fully recovers.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：
The coptis, nature and flavor：Bitter, cold, the effect of with purging intense heat, eliminating dampness, removing toxic substances, desinsection, row heat toxin, typhoid fever, heat are contained during for treating Vexed, feeling of fullness vomit inverse, bacillary dysentery, heat rush down stomachache, lung knot by, tell, be defeated in battle, lower blood, quench one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, roundworm disease, pertussis, throat swell Bitterly, the disease such as burning hot wound of pinkeye, aphtha, skin sore, eczema, soup；
Intelligence development, nature and flavor：Warm in nature, taste is pungent, with it is warming spleen and stopping diarrha take the photograph saliva, warm kidney astringent sperm contracting urine the effect of, let out for treating malaria Rush down, the disease such as crymodynia, many salivas of mouth, the kidney enuresis, frequent urination, the white candle of seminal emission in abdomen；
The Radix Astragali, nature and flavor：The effect of sweet, tepor, solid with polishing table, torr sore myogenic, for treat physically weak spontaneous perspiration, chronic diarrhea, prolapse of the anus, The diseases such as the prolapse of uterus, chronic nephritis, physically weak edema, chronic ulcer, the long disunion of the open sore part；
Radix Angelicae Sinensis, nature and flavor：Gan Xin, temperature, the effect of with benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treat irregular menstruation, After Amenorrhea stomachache, abdominal mass knot poly-, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestines are dry and shit is difficult, dysentery characterized by blood in the stool weight, ulcer sore steal, injury from falling down Deng disease；
The bighead atractylodes rhizome, nature and flavor：Bitter sweet, temperature, with tonifying spleen, beneficial stomach, eliminating dampness and in, it is antiabortive the effect of, for control deficient QI of the spleen and stomach, The few gas of do not feel like eating, burnout, empty swollen, diarrhea, phlegm and retained fluid, oedema, jaundice, arthritis with fixed pain caused by dampness, difficult urination, dizziness, spontaneous perspiration, nausea uneasiness etc. Disease；
Dried orange peel, nature and flavor：Bitter, pungent, temperature, with regulating qi-flowing for strengthening spleen, adjust in, eliminating dampness, clears phlegm, the gastral cavity for treating the taste stagnation of the circulation of vital energy Abdominal distension uncomfortable in chest, indigestion and loss of appetite loose stool in distention and fullness in the abdomen or pain, indigestion, wet turbid resistance, the cough and asthma of phlegm obstructing lung, deficiency of food are told Rush down, the disease such as coughing with a lot of sputum；
Polygonum multiflower knotweed, nature and flavor：It is sweet slight bitter, flat, with nourishing heart, calm the nerves, dredging collateral, wind-dispelling the effect of, for treating insomnia, internal lesion caused by overexertion, many The diseases such as sweat, deficiency of blood bodily pain, ulcer, scrofula, wind sore scabies tinea；
Mother-of-pearl, nature and flavor：It is salty, cool, the effect of with soothing the liver, checking exuberance of yang, arresting convulsion, hemostasis, for treatment head to be dizzy, tinnitus, palpitaition, mistake The diseases such as dormancy, demented, frightened epilepsy, haematemesis, bleeding from five sense organs or subcutaneous tissue, metrorrhagia；
Date, nature and flavor：Sweet, temperature, with tonifying spleen and stomach, nourishing generate fluid, adjust battalion to defend, antidote poison the effect of, for treating the empty food of stomach Less, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony between ying and wei, palpitation and severe palpitation；
Asparagus fern,（Original name lucid asparagus）Nature and flavor：It is sweet, bitter, cold in nature, it is dry for treating the effect of with nourshing Yin and drynsessmoistening prescription, clearing lung-heat fall fire The diseases such as heat cough, deficiency of Yin labor are coughed, consumption of YIN caused by febrile disease, Heat Diabetes, dry constipation of intestines, abscess of throat；
The tuber of pinellia, nature and flavor：It is pungent, warm, poisonous, it is cold for treating damp phlegm the effect of with eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass The diseases such as drink, vomiting, gastric disorder causing nausea, cough and phlegm, fullness in chest, phlegm and headache, dizziness and sleepless, outer subduing inflammation；
Ginseng, nature and flavor：Sweet, slight bitter, tepor, with tonifying Qi, take off admittedly, promote the production of body fluid, calming the nerves, intelligence development the effect of, breathed heavily for treating shortness of breath The disease such as rush, palpitation and amnesia, thirsty hidrosis, powerless deficiency of food, all acute and chronic diseases and the shock, the collapse that cause after losing blood.
Medicine of the present invention be based on Chinese traditional treatment depression the differentiation of disease with the dialectical principle being combined, from pharmacological action and work Thought with mechanism：With regard to depression, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, is had very well to above-mentioned disease Therapeutic effect.
Specific embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned depression, the medicine prepared using the formula Thing good drug efficacy, instant effect is a Chinese prescription treated both principal and secondary aspect of disease, and is particularly suitable for Clinical practice.With reference to tool of the invention Body implementation method is described in further detail：
Embodiment 1：
A kind of Chinese medicine composition for treating depression, it is characterised in that each component and its matter of the Chinese medicine composition Amount part is than as follows：
Coptis 4g, intelligence development 13g, Radix Astragali 23g, Radix Angelicae Sinensis 13g, bighead atractylodes rhizome 13g, dried orange peel 10g, Polygonum multiflower knotweed 15g, mother-of-pearl 35g, date 25g, asparagus fern 14g, tuber of pinellia 7g, ginseng 13g.
Embodiment 2：
A kind of Chinese medicine composition for treating depression, it is characterised in that each component and its matter of the Chinese medicine composition Amount part is than as follows：
Coptis 4.5g, intelligence development 14g, Radix Astragali 26g, Radix Angelicae Sinensis 14g, bighead atractylodes rhizome 14g, dried orange peel 11g, Polygonum multiflower knotweed 17g, mother-of-pearl 40g, date 28g, asparagus fern 14g, tuber of pinellia 8g, ginseng 14g.
Embodiment 3：
A kind of Chinese medicine composition for treating depression, it is characterised in that each component and its matter of the Chinese medicine composition Amount part is than as follows：
Coptis 5g, intelligence development 16g, Radix Astragali 30g, Radix Angelicae Sinensis 16g, bighead atractylodes rhizome 16g, dried orange peel 12g, Polygonum multiflower knotweed 20g, mother-of-pearl 45g, date 32g, asparagus fern 16g, tuber of pinellia 9g, ginseng 16g.
Model case：
Through clinical conditions patients with depression totally 160, the age is 95 of more than 28 years old, and only 65 is less than 28 years old. 85 fully recovered in 160 patients, effective 75, total effective rate is up to 100%.After treatment, symptom gradually mitigates or fully recovers.

Claims (3)

1. a kind of Chinese medicine composition for treating depression, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：
2.5~5g of the coptis, 5~16g of intelligence development, 15~30g of the Radix Astragali, 8~16g of Radix Angelicae Sinensis, 8~16g of the bighead atractylodes rhizome, 6~12g of dried orange peel, night hand over 10~20g of rattan, 15~45g of mother-of-pearl, 15~32g of date, 6~16g of asparagus fern, 3~9g of the tuber of pinellia, 2.5~16g of ginseng.
2. the Chinese medicine composition for treating depression according to claim 1, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：
3~4.5g of the coptis, 10~14g of intelligence development, 18~26g of the Radix Astragali, 10~14g of Radix Angelicae Sinensis, 10~14g of the bighead atractylodes rhizome, 8~11g of dried orange peel, night Hand over 12~17g of rattan, 20~40g of mother-of-pearl, 20~28g of date, 10~14g of asparagus fern, 6~8g of the tuber of pinellia, 10~14g of ginseng.
3. the Chinese medicine composition for treating depression according to claim 1 to 2, it is characterised in that the Chinese medicine group Each component and its mass parts of compound are than as follows：
Coptis 4g, intelligence development 13g, Radix Astragali 23g, Radix Angelicae Sinensis 13g, bighead atractylodes rhizome 13g, dried orange peel 10g, Polygonum multiflower knotweed 15g, mother-of-pearl 35g, date 25g, asparagus fern 14g, tuber of pinellia 7g, ginseng 13g.
CN201710182205.XA 2017-03-24 2017-03-24 A kind of Chinese medicine composition for treating depression and preparation method thereof Withdrawn CN106860816A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002089827A1 (en) * 2001-05-08 2002-11-14 Herbnex Inc. Composition for the prophylaxis or treatment of male reproductivity depression, or for the stimulation of haematogenesis
CN104258023A (en) * 2014-10-25 2015-01-07 刘树芹 Traditional Chinese medicine composition for treating depressive disorder
CN106138978A (en) * 2016-09-30 2016-11-23 四川易创生物科技有限公司 A kind of new medicine compositions treating depression and preparation method thereof
CN106237213A (en) * 2016-09-08 2016-12-21 四川聚豪生物科技有限公司 A kind of pill medicine treating depression and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002089827A1 (en) * 2001-05-08 2002-11-14 Herbnex Inc. Composition for the prophylaxis or treatment of male reproductivity depression, or for the stimulation of haematogenesis
CN104258023A (en) * 2014-10-25 2015-01-07 刘树芹 Traditional Chinese medicine composition for treating depressive disorder
CN106237213A (en) * 2016-09-08 2016-12-21 四川聚豪生物科技有限公司 A kind of pill medicine treating depression and preparation method thereof
CN106138978A (en) * 2016-09-30 2016-11-23 四川易创生物科技有限公司 A kind of new medicine compositions treating depression and preparation method thereof

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