CN106852996A - A kind of Chinese medicine composition and preparation method for treating essential hypertension - Google Patents

A kind of Chinese medicine composition and preparation method for treating essential hypertension Download PDF

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CN106852996A
CN106852996A CN201710092843.2A CN201710092843A CN106852996A CN 106852996 A CN106852996 A CN 106852996A CN 201710092843 A CN201710092843 A CN 201710092843A CN 106852996 A CN106852996 A CN 106852996A
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chinese medicine
medicine composition
essential hypertension
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孙素蓉
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Chengdu Fengmi Biotechnology Co Ltd
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Chengdu Fengmi Biotechnology Co Ltd
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    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which, according to a kind of Chinese medicine composition for treating essential hypertension that the traditional Chinese medical science is provided the understanding mechanism of essential hypertension, each component and its mass parts ratio of the Chinese medicine composition are as follows:50~120g of prepared RADIX ET RHIZOMA RHEI with wine, 30~60g of prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, 80~180g of cassia seed, 100~180g of Ramulus Taxilli, 60~350g of yncaria stem with hooks, 60~90g of Semen Leonuri, 80~180g of the root of kudzu vine, 60~160g of selfheal, 30~120g of Folium Apocyni Veneti, 50~160g of earthworm, 30~100g of Ligusticum wallichii, 100~180g of red yeast rice, 100~300g of chrysanthemum indicum;The medicine that the present invention is provided is a Chinese prescription treated both principal and secondary aspect of disease.

Description

A kind of Chinese medicine composition and preparation method for treating essential hypertension
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition for treating essential hypertension, The Chinese medicine composition for particularly being used for primary hypertension patient and the field of preparation method.
Background technology
Based on current medical development level and detection methods, it can be found that cause the elevated definite cause of disease of blood pressure, referred to as It is secondary hypertension;Conversely, can not find to cause the elevated definite cause of disease of blood pressure, then referred to as essential hypertension.Hypertension Most in crowd is essential hypertension, but essential hypertension of clarifying a diagnosis, secondary hypertension except needing first.Recognize at present For, secondary hypertension accounts for the 5%~10% of Hypertensive Population, but with the continuous progress of medical development level and detection methods, The ratio of secondary hypertension will be continuously increased, the ratio continuous decline of regular meeting of essential hypertension.
Essential hypertension is caused by h and E combined factors.American Society of Hypertension in 2005(ASH)Carry Go out, hypertension is the cardiovascular syndrome in continuous state of progress caused by many causes of disease, can cause heart and blood The change of pipe function and structure.Therefore, the main purpose of essential hypertension treatment is to reduce cardiovascular dead to greatest extent Die and invalid total danger.
So, it is those skilled in the art with regard to how to find a kind of medicine that can effectively treat above-mentioned essential hypertension Urgently problem to be resolved.
The content of the invention
With continuing to develop for China's traditional Chinese medicine, in treatment essential hypertension, during people gradually appreciate Cure the advantage for treating essential hypertension, and the advantage such as good effect, instant effect, toxic and side effect be small over the course for the treatment of, for existing There is the present situation of western medical treatment essential hypertension, the purpose of the present invention is to provide a kind of for treating essential hypertension Chinese medicine composition, to solve primary hypertension patient restorative problem early.The medicine is with common Chinese medicine as former Material, by selecting rational medicine and mass parts ratio, can effectively treat above-mentioned essential hypertension.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is:There is provided a kind of for treating primary The Chinese medicine composition and preparation method of hypertension, it is characterised in that each component and its mass parts ratio of the Chinese medicine composition It is as follows:
50~120g of prepared RADIX ET RHIZOMA RHEI with wine, 30~60g of prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, 80~180g of cassia seed, 100~180g of Ramulus Taxilli, 60~350g of yncaria stem with hooks, 60~90g of Semen Leonuri, 80~180g of the root of kudzu vine, 60~160g of selfheal, 30~120g of Folium Apocyni Veneti, 50~160g of earthworm, Ligusticum wallichii 30~100g, 100~180g of red yeast rice, 100~300g of chrysanthemum indicum.
A kind of Chinese medicine composition and preparation method for treating essential hypertension, it is characterised in that the Chinese medicine group Each component and its mass parts of compound are than as follows:
60~100g of prepared RADIX ET RHIZOMA RHEI with wine, 40~50g of prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, 90~160g of cassia seed, 115~160g of Ramulus Taxilli, 70~310g of yncaria stem with hooks, 70~85g of Semen Leonuri, 90~160g of the root of kudzu vine, 70~140g of selfheal, 40~105g of Folium Apocyni Veneti, 60~140g of earthworm, Ligusticum wallichii 40~90g, 115~160g of red yeast rice, 115~260g of chrysanthemum indicum.
A kind of Chinese medicine composition and preparation method for treating essential hypertension, it is characterised in that " the optimal side Each component and its mass parts of the Chinese medicine composition of case " are than as follows:
Prepared RADIX ET RHIZOMA RHEI with wine 90g, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 45g, cassia seed 140g, Ramulus Taxilli 140g, yncaria stem with hooks 280g, Semen Leonuri 75g, root of kudzu vine 140g, summer Withered grass 120g, Folium Apocyni Veneti 95g, earthworm 120g, Ligusticum wallichii 80g, red yeast rice 140g, chrysanthemum indicum 230g.
A kind of Chinese medicine composition and preparation method for treating essential hypertension, it is characterised in that methods described bag Following steps are included to be prepared from:
A, above-mentioned raw materials Chinese medicine is picked into impurity, dust and drying after, be ground into superfine end according to mass parts ratio stand-by;
B, the method that Chinese medicine capsules are prepared according to tradition, after ground superfine myrrh thing is sieved, are put into mixing in medicine device Uniformly, then it is prepared into capsule(The sealed rear total length of its capsule is 23.3mm, medicinal powder capacity 0.4~0.5g/), sealed packaging .
A kind of Chinese medicine composition and preparation method for treating essential hypertension, it is characterised in that the side of taking Method is:Three times a day to take, the morning, noon and afternoon service once the capsule medicine that will be prepared, dosage 2g(4)/ time, Wen Kai Water delivery service.It is within 10 days a course for the treatment of, after 2~4 courses for the treatment of of medication, checks:Blood pressure is normal, physical recovery health.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component:
Prepared RADIX ET RHIZOMA RHEI with wine, nature and flavor:Bitter, cold in nature, the effect of with purgating heat and bowels, for treating, Gastrointestinal excess heat is stagnant, big constipation Knot, belly turgor, pain with tenderness, the cold accumulation and constipation of even hyperpyrexia, such as coma and delirium, dachengqi decoction, or spleen sun deficiency, such as Wenpi decoction;
Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, nature and flavor:It is bitter, cold, the effect of with heat-clearing and damp-drying drug, purging intense heat and detonicating, for treat damp and hot feeling of fullness, vomiting acid regurgitation, Rush down dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head tells nosebleed, hot eyes, have a toothache, quench one's thirst, carbuncle swells furunculosis, control outward wet Rash, wet sore, duct are suppurated, and prepared RHIZOMA COPTIDIS with vino is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs intimately, for hot eyes, aphtha, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach anti-vomiting, for fever and chills Mutual knot, damp and hot middle resistance, feeling of fullness vomiting, the easypro liver anti-vomiting of cornel coptis, for liver-stomach disharmony, vomiting acid regurgitation;
Cassia seed, nature and flavor:Salty bitter, Pingliang, it is nontoxic, with expelling wind and clearing away heat, detoxification and promoting urination, anemopyretic cold, influenza, acute conjunctiva The diseases such as inflammation, jaundice with damp-heat pathogen, acute and chronic nephritis, under band, scrofula, sore carbuncle furuncle, mastitis;
Ramulus Taxilli, nature and flavor:It is bitter, sweet, mild-natured, with filling liver kidney, strengthening the bones and muscles, wind-damp dispelling, it is antiabortive the effect of, for treat waist and knee acid Bitterly, muscles and bones impotence is weak, limbs are hemiplegia, arthralgia pain due to rheumatism, dizzy head mistake, fetal irritability, metrostaxis;
Yncaria stem with hooks, nature and flavor:Sweetness and bitterness, it is slightly cold, the effect of with The flat liver of heat-clearing, relieving convulsion and spasm, for treating child convulsion, the morbid night crying of babies, heat Contain the diseases such as dynamic wind, eclampsia, dizziness due to hyperactivity of liver-YANG, irascibility distending pain in the head;
Semen Leonuri, nature and flavor:Sweet, pungent, cold nature, upper poison, with promoting blood circulation for regulating menstruation, clear liver and improve vision the effect of, for treating menstruation Uncomfortable, dysmenorrhoea, amenorrhoea, postpartum stasis of blood, the headache of liver heat, dizziness, red eye, swell pain, mesh life ocular;
The root of kudzu vine, nature and flavor:It is sweet, pungent, flat, brought down a fever with expelling pathogenic factors from muscles and skin, deliver examine, promote the production of body fluid to quench thirst, Shengyang Zhixie the effect of, for controlling Treat fever caused by exogenous pathogens, rigidity of nape and headache, measles and go out not smooth, thirsty warm disease, diabete, diarrhea, dysentery, hypertension, coronary disease from the beginning of, rash Disease;
Selfheal, nature and flavor:It is bitter, pungent, cold in nature, with clearing liver and improving vision, powder detoxifcation the effect of, for treating mesh also photophobia, mesh Pearl pain, dizziness of having a headache, tinnitus, scrofula, goiter and tumor, acute mastitis, mumps, carbuncle furuncle poison, acute hepatitis, chronic hepatitis, high blood pressure;
Folium Apocyni Veneti, nature and flavor:It is sweet, bitter, cool, calm the nerves with soothing the liver, clearing away heat and promoting diuresis the effect of, for treating dizziness due to hyperactivity of liver-YANG, palpitaition Insomnia, edema oliguria, high blood pressure, neurasthenia, ephritis edema;
Earthworm, nature and flavor:Cold in nature, taste is salty, with The flat liver of heat-clearing, relieving convulsion and spasm, relieving asthma, diuresis, dredging collateral eliminating impediment the effect of, for controlling Treat hyperpyrexia agitation, twitch, dyspnea and cough due to lung-heat, thermojunction renal shutdown, numbness pain limb fiber crops, hemiplegia, and sore swollen toxin;
Ligusticum wallichii, nature and flavor:Pungent, temperature, has functions that blood-activating and qi-promoting, wind-expelling pain-stopping, for pacifying neural, positive head wind headache, abdominal mass Stomachache, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism;
Red yeast rice, nature and flavor:Sweet, temperature, with helping digestion the effect of with stomach, promoting blood circulation and stopping pain, invigorating the spleen, dry stomach, for Therapeutic diet stagnation, chest The full vexed, indigestion of diaphragm;
Chrysanthemum indicum, nature and flavor:Be slightly cold, pungent, hardship, the effect of with wind and heat dispersing, subdhing swelling and detoxicating, for treat anemopyretic cold, pneumonia, Diphtheria, gastroenteritis, hypertension, malignant boil, carbuncle, aphtha, erysipelas, eczema, epidemic blisters.
Medicine of the present invention is the principle based on Chinese traditional treatment essential hypertension, from the pathology machine according to essential hypertension System and pharmacological action are thought:With regard to essential hypertension, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, to upper Stating disease has good therapeutic effect.
Specific embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned essential hypertension, using the formula system Standby medicine effect is good, instant effect, is a Chinese prescription treated both principal and secondary aspect of disease, and is particularly suitable for Clinical practice.With reference to this hair Bright specific embodiment is described in further detail:
Embodiment 1:
A kind of Chinese medicine composition for treating essential hypertension, it is characterised in that each component of the Chinese medicine composition And its mass parts are than as follows:
Prepared RADIX ET RHIZOMA RHEI with wine 90g, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 45g, cassia seed 140g, Ramulus Taxilli 140g, yncaria stem with hooks 280g, Semen Leonuri 75g, root of kudzu vine 140g, summer Withered grass 120g, Folium Apocyni Veneti 95g, earthworm 120g, Ligusticum wallichii 80g, red yeast rice 140g, chrysanthemum indicum 230g.
Embodiment 2:
A kind of Chinese medicine composition for treating essential hypertension, it is characterised in that each component of the Chinese medicine composition And its mass parts are than as follows:
Prepared RADIX ET RHIZOMA RHEI with wine 100g, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 50g, cassia seed 160g, Ramulus Taxilli 160g, yncaria stem with hooks 310g, Semen Leonuri 85g, root of kudzu vine 160g, summer Withered grass 140g, Folium Apocyni Veneti 105g, earthworm 140g, Ligusticum wallichii 90g, red yeast rice 160g, chrysanthemum indicum 260g.
Embodiment 3:
A kind of Chinese medicine composition for treating essential hypertension, it is characterised in that each component of the Chinese medicine composition And its mass parts are than as follows:
Prepared RADIX ET RHIZOMA RHEI with wine 120g, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 60g, cassia seed 180g, Ramulus Taxilli 180g, yncaria stem with hooks 350g, Semen Leonuri 90g, root of kudzu vine 180g, summer Withered grass 160g, Folium Apocyni Veneti 120g, earthworm 160g, Ligusticum wallichii 100g, red yeast rice 180g, chrysanthemum indicum 300g.
Model case
Through clinical conditions primary hypertension patient totally 590, the age is 360 of more than 58 years old, and only 230 is 58 Year is following.480 fully recovered in 590 patients, effective 110, total effective rate is up to 100%.

Claims (3)

1. a kind of Chinese medicine composition for treating essential hypertension, it is characterised in that each group of the Chinese medicine composition Divide and its mass parts are than as follows:
50~120g of prepared RADIX ET RHIZOMA RHEI with wine, 30~60g of prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, 80~180g of cassia seed, 100~180g of Ramulus Taxilli, 60~350g of yncaria stem with hooks, 60~90g of Semen Leonuri, 80~180g of the root of kudzu vine, 60~160g of selfheal, 30~120g of Folium Apocyni Veneti, 50~160g of earthworm, Ligusticum wallichii 30~100g, 100~180g of red yeast rice, 100~300g of chrysanthemum indicum.
2. the Chinese medicine composition for treating essential hypertension according to claim 1, it is characterised in that the Chinese medicine Each component and its mass parts of composition are than as follows:
60~100g of prepared RADIX ET RHIZOMA RHEI with wine, 40~50g of prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice, 90~160g of cassia seed, 115~160g of Ramulus Taxilli, 70~310g of yncaria stem with hooks, 70~85g of Semen Leonuri, 90~160g of the root of kudzu vine, 70~140g of selfheal, 40~105g of Folium Apocyni Veneti, 60~140g of earthworm, Ligusticum wallichii 40~90g, 115~160g of red yeast rice, 115~260g of chrysanthemum indicum.
3. the Chinese medicine composition for treating essential hypertension according to claim 1 to 2, it is characterised in that described Each component and its mass parts of Chinese medicine composition are than as follows:
Prepared RADIX ET RHIZOMA RHEI with wine 90g, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice 45g, cassia seed 140g, Ramulus Taxilli 140g, yncaria stem with hooks 280g, Semen Leonuri 75g, root of kudzu vine 140g, summer Withered grass 120g, Folium Apocyni Veneti 95g, earthworm 120g, Ligusticum wallichii 80g, red yeast rice 140g, chrysanthemum indicum 230g.
CN201710092843.2A 2017-02-21 2017-02-21 A kind of Chinese medicine composition and preparation method for treating essential hypertension Pending CN106852996A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102670785A (en) * 2010-11-29 2012-09-19 天士力制药集团股份有限公司 Preparation method of conventional Chinese medicine composition for treating primary hypertension

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102670785A (en) * 2010-11-29 2012-09-19 天士力制药集团股份有限公司 Preparation method of conventional Chinese medicine composition for treating primary hypertension

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