CN106822524B - Compound medicine for treating infertility and preparation method and application thereof - Google Patents

Compound medicine for treating infertility and preparation method and application thereof Download PDF

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CN106822524B
CN106822524B CN201710249999.7A CN201710249999A CN106822524B CN 106822524 B CN106822524 B CN 106822524B CN 201710249999 A CN201710249999 A CN 201710249999A CN 106822524 B CN106822524 B CN 106822524B
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compound medicine
treating infertility
vinegar
filtrate
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CN106822524A (en
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张华�
孙自学
门波
陈建设
李鹏超
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Henan Hospital Traditional Chinese Medicine Second Affiliated Hospital of Henan University of Traditional Chinese Medicine TCM
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract

The invention provides a compound medicine for treating infertility and a preparation method and application thereof, relating to the technical field of traditional Chinese medicines. A compound medicine for treating infertility comprises the following raw materials in parts by weight: 20-40 parts of salvia miltiorrhiza, 20-40 parts of vinegar rhizoma corydalis, 10-20 parts of sargentgloryvine stem, 10-20 parts of moutan bark and 8-16 parts of vinegar rhizoma cyperi. The compound medicine has effects of promoting blood circulation, removing blood stasis, activating qi-flowing, relieving pain, clearing heat and detoxicating, and has no damage to liver and kidney, and no side effect. A preparation method of a compound medicine for treating infertility comprises the following steps: the raw material is subjected to solvent extraction. The preparation method is simple and easy to implement, has strong operability, can well extract effective components, and ensures the drug effect.

Description

Compound medicine for treating infertility and preparation method and application thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and in particular relates to a compound medicine for treating infertility and a preparation method and application thereof.
Background
With the opening of the two-birth policy, China will be in the way of a new round of breeding hot tide. Meanwhile, infertility also becomes a difficult problem due to various environmental and health factors. The investigation report of the current situation of infertility published by the Chinese population Association in 2010 shows that the incidence rate of infertility in one year is 10%, the incidence rate of infertility in two years is 15%, and no child accounts for 25% in 10 years. The minimum 23 years of age and the maximum 40 years of age for the visit. In the female infertility patients, the fallopian tube is frequently infertile.
The patency of human fallopian tubes is one of the essential main conditions for pregnancy, the tube cavity of the fallopian tubes is narrow, and the diameter of the tube cavity of the narrowest part is only 1-2 mm. Inflammation of organs adjacent to the fallopian tube, such as appendicitis infection, can also be prolonged to the fallopian tube, causing fallopian tube adhesion and pelvic adhesion. Inflammation of the fallopian tube can be caused by ascending infection such as vaginitis, cervicitis, endometritis and the like. Genitalia inflammation appears in female during abortion, intrauterine contraceptive ring placement, oviduct fluid-passing operation and other uterine cavity operations, which leads to oviduct blockage. When salpingitis or pelvic inflammation occurs, the narrowest part and the umbrella end of the fallopian tube are easy to be adhered or completely blocked. Thus, all can lead to female infertility. In order to avoid surgery and relieve pain of patients, new effective medicines have important effects on treating diseases such as infertility and the like.
Disclosure of Invention
The invention aims to provide a compound medicine for treating infertility, which has the effects of promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain, clearing heat and removing toxicity, and has no damage to liver and kidney and no side effect.
The invention also aims to provide a preparation method of the compound medicine for treating infertility, which is simple and easy to implement, has strong operability, and can well extract effective components to ensure the efficacy.
The technical problem to be solved by the invention is realized by adopting the following technical scheme:
the invention provides a compound medicine for treating infertility, which is prepared from the following raw materials in parts by weight: 20-40 parts of salvia miltiorrhiza, 20-40 parts of vinegar rhizoma corydalis, 10-20 parts of sargentgloryvine stem, 10-20 parts of moutan bark and 8-16 parts of vinegar rhizoma cyperi.
The invention provides a preparation method of a compound medicine for treating infertility, which comprises the following steps: the raw material is subjected to solvent extraction.
The compound medicine for treating infertility and the preparation method and the application thereof of the embodiment of the invention have the beneficial effects that:
the formula of the compound medicine for treating infertility mainly takes the effects of promoting blood circulation to remove blood stasis, promoting qi circulation and relieving pain, and has obvious curative effect on infertility. Wherein, the salvia miltiorrhiza promotes blood circulation to remove blood stasis, dredges meridians to relieve pain, cools blood and eliminates carbuncle; vinegar rhizoma corydalis can promote blood circulation, promote qi circulation, and relieve pain; caulis Sargentodoxae has effects of clearing away heat and toxic materials, promoting blood circulation, dispelling pathogenic wind and relieving pain; cortex moutan has effects of clearing heat and cooling blood, and promoting blood circulation for removing blood stasis; vinegar rhizoma Cyperi has effects of dispersing stagnated liver qi, relieving qi stagnation, regulating qi-flowing, relieving epigastric distention, regulating menstruation and relieving pain; herba Patriniae has effects of clearing away heat and toxic materials, dispelling blood stasis, and expelling pus; the cordate houttuynia has the effects of clearing heat and removing toxicity, eliminating carbuncle and discharging pus; fructus Cnidii has effects of eliminating dampness, dispelling pathogenic wind, killing parasites and relieving itching.
The formula conforms to the theory of traditional Chinese medicine and pharmacy, has the effects of promoting blood circulation to remove blood stasis, diminishing inflammation and relieving pain and improving the autoimmunity, and has obvious curative effect on infertility caused by gynecological diseases. Has no damage to internal organs and no adverse side effects.
The preparation method of the compound medicine for treating infertility adopts a solvent extraction mode to prepare the medicine, has high utilization rate of medicinal materials, is easier to be absorbed by human bodies, has obvious medicine effect, and has simple preparation process.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
The compound medicine for treating infertility, the preparation method and the application thereof according to the embodiments of the present invention are specifically described below.
The embodiment of the invention provides a compound medicine for treating infertility, which is prepared from the following raw materials in parts by weight: 20-40 parts of salvia miltiorrhiza, 20-40 parts of vinegar rhizoma corydalis, 10-20 parts of sargentgloryvine stem, 10-20 parts of moutan bark and 8-16 parts of vinegar rhizoma cyperi.
Further, in the preferred embodiment of the present invention, the raw materials comprise, by weight: 25-35 parts of salvia miltiorrhiza, 25-35 parts of vinegar rhizoma corydalis, 12-18 parts of sargentgloryvine stem, 12-18 parts of moutan bark and 10-14 parts of vinegar rhizoma cyperi.
Further, in a preferred embodiment of the present invention, the raw materials further include, in parts by weight: 8-16 parts of patrinia, 8-16 parts of houttuynia cordata and 8-16 parts of fructus cnidii.
Further, in the preferred embodiment of the present invention, the raw materials comprise, by weight: 25-35 parts of salvia miltiorrhiza, 25-35 parts of vinegar rhizoma corydalis, 12-18 parts of sargentgloryvine stem, 12-18 parts of moutan bark, 10-14 parts of vinegar rhizoma cyperi, 8-16 parts of herba patriniae, 8-16 parts of houttuynia cordata and 8-16 parts of fructus cnidii.
Further, in the preferred embodiment of the present invention, the raw materials comprise, by weight: 30 parts of salvia miltiorrhiza, 30 parts of vinegar-processed corydalis tuber, 15 parts of sargentgloryvine stem, 15 parts of tree peony bark, 12 parts of vinegar-processed cyperus rotundus, 12 parts of patrinia, 12 parts of houttuynia cordata and 12 parts of fructus cnidii.
The prescription rule of the compound medicine follows the prescription rule in the traditional Chinese medicine, has the effects of promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain, clearing heat and removing toxicity, is used for promoting blood circulation to remove blood stasis, diminishing inflammation and relieving pain, and improving autoimmunity, and has obvious curative effect on infertility caused by gynecological diseases.
Dan Shen is bitter and slightly cold. It enters heart and liver meridians. Has the effects of promoting blood circulation, removing blood stasis, dredging channels, relieving pain, cooling blood and resolving carbuncle. The Saviae Miltiorrhizae radix can inhibit or relieve cell necrosis and inflammatory reaction, promote tissue repair and regeneration, relieve topical blood stasis, and improve blood circulation. The red sage root has less side effect and reliable medicinal effect.
Vinegar-processed corydalis tuber, pungent, bitter and warm. It enters liver and spleen meridians. Has effects in promoting blood circulation, activating qi-flowing, and relieving pain. Yan Hu Suo is specially indicated for all pains of upper and lower parts of the body because it can promote qi stagnation in blood and qi stagnation in middle and blood. Vinegar rhizoma corydalis is prepared by processing rhizoma corydalis. Specifically, the clean corydalis tuber is taken and evenly stirred with vinegar, soaked until the vinegar is absorbed completely, put into a pot and fried by slow fire until the vinegar is slightly dry, taken out and cooled; or decocting rhizoma corydalis in vinegar in a pot until the vinegar is completely absorbed, oven drying, taking out, and cooling. Vinegar rhizoma corydalis can improve the solubility of effective components of rhizoma corydalis in decoction, thereby enhancing therapeutic effect.
The compatibility of the two can promote blood circulation by removing blood stasis, dredge the channels and relieve pain.
Da Xue Teng, bitter and even. It enters large intestine and liver meridians. Has the effects of clearing away heat and toxic materials, promoting blood circulation, dispelling pathogenic wind, and relieving pain.
Mu Dan Pi is bitter, pungent and slightly cold. It enters heart, liver and kidney meridians. Has effects of clearing heat, cooling blood, promoting blood circulation and removing blood stasis. Cortex moutan has anti-inflammatory effect, and can directly resist inflammation medium, inhibit leukocyte migration and inhibit biosynthesis of prostaglandin. Cortex moutan has different degrees of inhibition on Escherichia coli, Bacillus dysenteriae, hemolytic streptococcus, etc. And cortex moutan has the function of activating immune system, and can enhance immunity of organism.
Vinegar-processed Cyperus rotundus, pungent, slightly bitter, slightly sweet and neutral. It enters liver, spleen and triple energizer meridians. Has effects in regulating qi, relieving epigastric distention, regulating menstruation, relieving pain, and resisting inflammation and bacteria.
The compatibility of the three medicines can promote blood circulation, regulate menstruation and relieve pain, and has the efficacy of anti-inflammation. The auxiliary materials of the salvia miltiorrhiza and the vinegar rhizoma corydalis can promote blood circulation to remove blood stasis and dredge channels to relieve pain.
Bai Jiang Cao is cool in nature, pungent and bitter in taste. Has the effects of clearing away heat and toxic materials, removing blood stasis and expelling pus. It has effects in inhibiting Staphylococcus aureus and Escherichia coli, promoting cell regeneration, and resisting virus. Herba Patriniae can also improve immunity.
Yu xing Cao, pungent and slightly cold. It enters lung meridian. Has effects of clearing away heat and toxic materials, eliminating carbuncle, expelling pus, promoting urination, and treating stranguria. The extract of houttuynia cordata has inhibitory effect on various microorganisms, hemolytic streptococcus, Staphylococcus aureus, Bacillus influenzae, Escherichia coli, etc., and tissue edema, and can inhibit serous fluid exudation, promote tissue regeneration and wound healing. Herba Houttuyniae can enhance phagocytosis of leukocyte and macrophage, and improve immunity.
Fructus cnidii, pungent, bitter and warm; has little toxicity. It enters kidney meridian. Has effects of eliminating dampness, dispelling pathogenic wind, killing parasites and relieving itching. Fructus Cnidii has effects of enhancing physical strength and enhancing immunity, and has effects of inhibiting Staphylococcus aureus and Pseudomonas aeruginosa, resisting bacteria and inflammation.
The compatibility of the three medicines can clear away heat and toxic material, cure carbuncle and discharge pus, sterilize and relieve itching. The auxiliary materials of the salvia miltiorrhiza and the vinegar rhizoma corydalis can promote blood circulation to remove blood stasis and dredge channels to relieve pain.
The preparation method of the compound medicine for treating infertility provided by the embodiment of the invention comprises the following steps:
cleaning raw materials, crushing, and extracting effective components from the raw materials;
soaking the treated raw materials in cold water for 20-30 min, wherein the addition of the water is 2-3 cm higher than that of the medicinal materials; the cold water is generally 0 to 30 ℃.
After soaking, boiling with strong fire, decocting with slow fire for 25-35 minutes, and filtering to obtain a first filtrate; wherein the strong fire is 300-400 ℃, and the slow fire is 130-170 ℃.
Adding water into the filtered decoction dregs, wherein the water is generally added to the decoction dregs in an amount of 1-2 cm higher than the medicinal materials, boiling the decoction with strong fire, then decocting the decoction with slow fire for 15-25 minutes, and filtering to obtain a second filtrate;
mixing the first and second filtrates, boiling with strong fire, decocting with slow fire, and concentrating.
The mode of administration of the drug prepared in the examples of the present invention was rectal infusion. Through the rapid absorption of the rectal mucosa, the blood vessels of the lesion part are expanded, and the adhesion of the lesions is relaxed, so that the dredging of the lumen is accelerated, the medicine enters the human body circulation, and the medicine effect is better exerted. The efficacy is not influenced by a plurality of factors of the digestive tract, the maintenance time is long, and the curative effect is improved. Preferably, the medicament is used once a day and 7-15 days a month. The liquid medicine is heated to 37-40 ℃ and then administered, so that the absorption of the body to the liquid medicine is increased, the blood circulation of the pelvic cavity is improved, and hyperplastic tissues are softened. The dosage is 100ml, and the administration time is 30 min.
The compound medicine for treating infertility provided by the invention can be used for preparing medicines for treating gynecological diseases.
Further, in preferred embodiments of the invention, the gynecological disease includes pelvic inflammatory disease, endometritis, cervicitis.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 25 parts of salvia miltiorrhiza, 25 parts of vinegar-processed corydalis tuber, 12 parts of sargentgloryvine stem, 12 parts of tree peony bark, 10 parts of vinegar-processed rhizoma cyperi, 8 parts of patrinia, 8 parts of heartleaf houttuynia herb and 8 parts of common cnidium fruit.
Drying and crushing the raw materials, mixing, and soaking in cold water for 20 min. Boiling with strong fire, decocting with slow fire for 25min, and filtering to obtain filtrate.
Example 2
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 35 parts of salvia miltiorrhiza, 35 parts of vinegar-processed corydalis tuber, 18 parts of sargentgloryvine stem, 18 parts of moutan bark, 14 parts of vinegar-processed rhizoma cyperi, 16 parts of patrinia, 16 parts of houttuynia cordata and 16 parts of fructus cnidii.
Drying and crushing the raw materials, mixing, and soaking in cold water for 30 min. Boiling with strong fire, decocting with slow fire for 35 min, and filtering to obtain filtrate.
Example 3
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 30 parts of salvia miltiorrhiza, 30 parts of vinegar-processed corydalis tuber, 15 parts of sargentgloryvine stem, 15 parts of tree peony bark, 12 parts of vinegar-processed cyperus rotundus, 12 parts of patrinia, 12 parts of houttuynia cordata and 12 parts of fructus cnidii.
Drying and crushing the raw materials, mixing, and soaking in cold water for 25 min. Boiling with strong fire, decocting with slow fire for 30min, and filtering to obtain filtrate.
Example 4
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 25 parts of salvia miltiorrhiza, 25 parts of vinegar-processed corydalis tuber, 12 parts of sargentgloryvine stem, 14 parts of moutan bark, 14 parts of vinegar-processed rhizoma cyperi, 8 parts of patrinia, 16 parts of houttuynia cordata and 8 parts of fructus cnidii.
Drying and crushing the raw materials, mixing, and soaking in cold water for 20 min. Boiling with strong fire, decocting with slow fire for 35 min, and filtering to obtain first filtrate;
adding water into the filtered dregs, boiling with strong fire, decocting with slow fire for 25 minutes, and filtering to obtain a second filtrate;
mixing the first and second filtrates, boiling with strong fire, decocting with slow fire, and concentrating.
Example 5
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 35 parts of salvia miltiorrhiza, 35 parts of vinegar-processed corydalis tuber, 12 parts of sargentgloryvine stem, 16 parts of moutan bark, 12 parts of vinegar-processed cyperus rotundus, 10 parts of patrinia, 10 parts of houttuynia cordata and 12 parts of fructus cnidii.
Drying and crushing the raw materials, mixing, and soaking in cold water for 30 min. Boiling with strong fire, decocting with slow fire for 30min, and filtering to obtain first filtrate;
adding water into the filtered dregs, boiling with strong fire, decocting with slow fire for 25 minutes, and filtering to obtain a second filtrate;
mixing the first and second filtrates, boiling with strong fire, decocting with slow fire, and concentrating.
Example 6
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 27 parts of salvia miltiorrhiza, 29 parts of vinegar-processed corydalis tuber, 15 parts of sargentgloryvine stem, 16 parts of moutan bark, 14 parts of vinegar-processed rhizoma cyperi, 10 parts of patrinia, 12 parts of houttuynia cordata and 10 parts of fructus cnidii.
Drying and crushing the raw materials, mixing, and soaking in cold water for 30 min. Boiling with strong fire, decocting with slow fire for 35 min, and filtering to obtain first filtrate;
adding water into the filtered dregs, boiling with strong fire, decocting with slow fire for 25 minutes, and filtering to obtain a second filtrate;
mixing the first and second filtrates, boiling with strong fire, decocting with slow fire, and concentrating.
Example 7
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 35 parts of salvia miltiorrhiza, 35 parts of vinegar-processed corydalis tuber, 18 parts of sargentgloryvine stem, 18 parts of moutan bark, 14 parts of vinegar-processed rhizoma cyperi, 16 parts of patrinia, 16 parts of houttuynia cordata and 16 parts of fructus cnidii.
Drying and crushing the raw materials, mixing, and soaking in cold water for 30 min. Boiling with strong fire, decocting with slow fire for 35 min, and filtering to obtain first filtrate;
adding water into the filtered dregs, boiling with strong fire, decocting with slow fire for 25 minutes, and filtering to obtain a second filtrate;
mixing the first and second filtrates, boiling with strong fire, decocting with slow fire, and concentrating.
Example 8
The embodiment provides a compound medicine for treating infertility, which is prepared by the following steps:
weighing the following raw materials: 30 parts of salvia miltiorrhiza, 30 parts of vinegar-processed corydalis tuber, 15 parts of sargentgloryvine stem, 15 parts of tree peony bark, 12 parts of vinegar-processed cyperus rotundus, 12 parts of patrinia, 12 parts of houttuynia cordata and 12 parts of fructus cnidii.
Drying and crushing the raw materials, mixing, and soaking in cold water for 30 min. Boiling with strong fire, decocting with slow fire for 30min, and filtering to obtain first filtrate;
adding water into the filtered dregs, boiling with strong fire, decocting with slow fire for 20 minutes, and filtering to obtain a second filtrate;
mixing the first and second filtrates, boiling with strong fire, decocting with slow fire, and concentrating.
Comparative example 1
A compound medicine for treating infertility is prepared by the following steps:
weighing the following raw materials in parts by weight: 15 parts of sargentgloryvine stem, 15 parts of tree peony bark, 12 parts of vinegar-processed rhizoma cyperi, 12 parts of patrinia, 12 parts of houttuynia cordata and 12 parts of fructus cnidii. Mixing, boiling with strong fire, decocting with slow fire for 30min, and filtering to obtain filtrate.
Comparative example 2
A compound medicine for treating infertility is prepared by the following steps:
weighing the following raw materials in parts by weight: 30 parts of salvia miltiorrhiza and 30 parts of vinegar rhizoma corydalis. Mixing, boiling with strong fire, decocting with slow fire for 30min, and filtering to obtain filtrate.
Test example 1 animal test
1. Establishment of animal model
110 female mice were collected and kept for weight (20. + -.2) g without mating.
2. Grouping and medicine feeding
Selecting 110 successfully established rats, weighing, marking, randomly dividing into 11 groups, and each group comprises 10 rats, which respectively correspond to a blank control group, examples 1-8 and comparative examples 1-2. The blank control group was filled with 0.85 wt% sodium chloride starting the day after molding. The compound medicines provided in the examples 1-8 and the traditional Chinese medicines 10g provided in the comparative examples 1-2 are respectively prepared into medicine solutions with the concentration of 2g/ml, and rats are enema according to 1ml/100 g.
3. Specimen collection
After 20 days of administration, the neck was cut off and sacrificed, blood was taken from the heart of the rat, and the contents of estradiol and progesterone in the serum were measured.
4. Results and analysis
TABLE 1 comparison of estradiol and progesterone content after administration
Figure BDA0001271814440000111
Figure BDA0001271814440000121
As can be seen from Table 1, the mean level of serum estradiol and progesterone in the rats using the compound drugs provided in examples 1-8 is higher than that in the rats of comparative example and comparative example 2. The sex hormone level of the rats in the experimental group is obviously higher than that of the rats in the blank control group. The compound medicine prepared in the examples 1 to 8 improves blood circulation, enhances the immunity of the organism and increases the pregnancy probability. Among them, example 8 is the most effective.
Test example 2 clinical test
1. Case selection
All cases were from patients diagnosed with gynecological disease in zhengzhou hospitals. 80 patients were selected as study subjects, and the age was 20-45 years. The groups were divided into 8 groups of 10 patients, each group corresponded to examples 1-8, and the difference was not statistically significant (p >0.05) when the general data such as the disease stage of each group of patients were compared.
2. Method of treatment
The patients take the compound medicines provided in examples 1 to 8 respectively by adopting a rectal infusion mode. The preparation is administered 1 time daily, 100ml each time, and 7 days as a treatment course.
3. Criteria for therapeutic effect
And (3) curing: the inflammation disappears, the pain and the related symptoms are basically avoided, the body is healthy, and the disease does not relapse after half a year of follow-up visit.
The effect is shown: the inflammation is reduced, the discomfort is obviously reduced, the menstruation is normal, the relapse is not seen in the follow-up visit for half a year, and the main examination indicates that the recovery is obvious.
The method has the following advantages: the inflammation and related symptoms are improved, the spirit is recovered, the complexion is good, the pain is relieved earlier, and the main improvement is realized before the examination and the treatment.
And (4) invalidation: the inflammation is not reduced and still uncomfortable.
The results of the tests are shown in Table 2.
4. Results and analysis
TABLE 2 results of clinical effects
Figure BDA0001271814440000131
Figure BDA0001271814440000141
According to Table 2, the following results were obtained: the total effective rate of patients using the compound medicines provided by the embodiments 1 to 8 is higher, which shows that the compound medicines provided by the embodiments 1 to 8 have reasonable formula and more scientific preparation method, so the treatment effect is good. The compound medicine prepared in the embodiment 6 has the highest effective rate, which indicates that the formula and the preparation method of the embodiment are more reasonable.
Typical case 1
In plum, a woman in 28 years old was diagnosed with infertility. The symptoms are: the menstruation is rare, and the contraceptive is not performed for 1 year. After 2 months of treatment, the menstruation is normal. After 4 months of treatment, the patient was pregnant normally.
Typical case 2
Wangzhi, female, age 30, was diagnosed as infertility. The symptoms are menstrual disorder, dysmenorrhea, gynecological inflammation and non-pregnancy of 1 year without contraception. After the compound medicine is used for treating 3 months, the menstruation is normal, and the examination result shows that the inflammation is reduced. After 6 months of treatment, the examination result shows that the inflammation is cured. After 10 months of treatment, the patient was pregnant normally.
Typical case 3
If someone is a woman in 32 years old, infertility is diagnosed. The disease is that the oviduct is blocked, the hospital requires to carry out the operation, and the patient starts to take the traditional Chinese medicine after giving up the operation treatment. After taking the medicine for two months, the physical condition of the patient is improved, and the examination result shows that the inflammation is reduced. After taking for half a year, the examination result shows that the fallopian tube is unobstructed. After taking the medicine for one year, the patient is pregnant normally.
In conclusion, the compound medicine for treating infertility provided by the embodiment of the invention has the effects of promoting blood circulation to remove blood stasis, diminishing inflammation, relieving pain and improving autoimmunity, and has a remarkable curative effect on infertility caused by gynecological diseases.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Claims (4)

1. The compound medicine for treating infertility is characterized in that the raw materials for preparing the compound medicine are as follows according to parts by weight: 30 parts of salvia miltiorrhiza, 30 parts of vinegar-processed corydalis tuber, 15 parts of sargentgloryvine stem, 15 parts of tree peony bark, 12 parts of vinegar-processed cyperus rotundus, 12 parts of patrinia, 12 parts of houttuynia cordata and 12 parts of fructus cnidii.
2. A method for preparing a compound medicine for treating infertility according to claim 1, comprising: the raw material is subjected to solvent extraction.
3. The method for preparing a compound medicine for treating infertility according to claim 2, wherein the solvent extraction of the raw materials is a decoction method comprising: boiling with strong fire, decocting with slow fire for 25-35 minutes, and filtering to obtain a first filtrate; adding water into the filtered decoction dregs, boiling the decoction dregs with strong fire, then decocting the decoction dregs with slow fire for 15-25 minutes, filtering the decoction dregs to obtain a second filtrate, and combining the first filtrate and the second filtrate.
4. The method for preparing a compound medicine for treating infertility according to claim 3, further comprising, after combining the first filtrate and the second filtrate: boiling the combined liquid medicine with the strong fire, and then decocting and concentrating with the slow fire.
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