CN106820157A - One kind is applied to teen-age health food - Google Patents

One kind is applied to teen-age health food Download PDF

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Publication number
CN106820157A
CN106820157A CN201710032788.8A CN201710032788A CN106820157A CN 106820157 A CN106820157 A CN 106820157A CN 201710032788 A CN201710032788 A CN 201710032788A CN 106820157 A CN106820157 A CN 106820157A
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CN
China
Prior art keywords
powder
health food
vitamin
folic acid
acid
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Pending
Application number
CN201710032788.8A
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Chinese (zh)
Inventor
张磊
陈平
田敏卿
李江
徐希平
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Shenzhen Taile De Nutrition And Health Co Ltd
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Shenzhen Taile De Nutrition And Health Co Ltd
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Priority to CN201710032788.8A priority Critical patent/CN106820157A/en
Publication of CN106820157A publication Critical patent/CN106820157A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a kind of health food for having auxiliary protection or facilitation to teenager's eyesight, hemopoietic system and intelligence development, the health food is by the μ g of vitamin A 250~800, the μ g of folic acid 400~800, vitamin B125~20 μ g and appropriate amount of auxiliary materials are constituted.The definite vitamin of the selected function of the present invention, carries out scientific composition, for specific crowd, is acted on function synergic between each composition, so as to embody the accurate nutritive peculiarity of this health food.

Description

One kind is applied to teen-age health food
Technical field
The present invention relates to a kind of health food, more precisely, the present invention relates to a kind of to teenager's eyesight, hemopoietic system And intelligence development has the health food of auxiliary protection function.
Background technology
Current teen-age hypopsia problem is quite serious.According to investigations, sight impaired individuals proportion connects in teenager Nearly 80%, and with age, this ratio is also being continued to increase.The reason for teenager's hypopsia (myopia, amblyopia) Except having outside the Pass with reading eye, also with the popularization of smart mobile phone, computer, other various electronic products using closely related, especially Its teenager is more easy to preference or even addicted this kind of product.Eyes are also easily caused using electronic product for a long time dry and astringent.According to statistics, People's emmetropia blinks number of times for 15 times per minute, and during computation is only 4-5 times, and the number of times that such as blinks reduces by 75%, Jiu Huiyin Lacrimal secretion is significantly reduced, the aerial time lengthening of corneal exposure, more than breakup time of tear film, therefore cannot be formed complete Tear film and easily cause to suffer from xerophthalmia.
On the other hand, the folic acid intake of investigation display many national crowds in the world is not enough, Chinese this problem because Genetic background and more aobvious protrusion (aftermentioned).Also there is partial eclipse phenomenon in the teenager based on middle school student, noon often eats Western-style outside Fast food (is commonly called as " junk food ", such as chips, fried drumstick), high heat, but the food species of intake are few, especially green Vegetables are few, are easily caused folic acid, vitamin B12Deng shortage;Along with Chinese family is accustomed to high-temperature cooking food, folic acid and dimension life Plain B12Easily destroyed, its effective intake is not enough, easily triggers megaloblastic anemia, reduces resistance against diseases.Additionally, folic acid Brain function is promoted to play, vitamin B12Nutritious nerve, enhancing memory effect, both can cooperate with promotion juvenile intelligence to develop.
B B-complex product is numerous in the market, mostly nutritious supplementary pharmaceutical, and various people can all take, but due into Point many, every kind of constituent content is relatively low, and lack of targeted, actual health-care effect is in the lap of future.Therefore, it is contemplated that exploitation is a kind of The nutrient and healthcare products of auxiliary protection teenager eyesight, prevention anaemia and promotion intelligence development, are to existing multivitamin product Significantly improve, also comply with the current trend for implementing accurate nutrition to specific crowd.
The content of the invention
There are auxiliary protection or rush to teenager's eyesight, hemopoietic system and intelligence development it is an object of the invention to provide a kind of Enter the health food of effect.
To achieve these goals, the present invention uses following technical scheme:
A kind of health food for having auxiliary protection or facilitation to teenager's eyesight, hemopoietic system and intelligence development, by Following component is constituted:
(1) vitamin A
(2) folic acid
(3) vitamin B12
(4) auxiliary material.
In above-mentioned health food, vitamin A content is 250~800 μ g, and folate content is 200~800 μ g, vitamin B12Content is 5~20 μ g.
Preferably, health food of the present invention, vitamin A content be 600~800 μ g, folate content be 400~ 600 μ g, vitamin B12Content is 5~10 μ g.
In the present invention, described folic acid includes folic acid, 5-methyltetrahydrofolate, formyl tetrahydrofolic acid, folinic acid, Zuo Yaye Sour calcium etc., i.e., including artificial synthesized and plant extract source various forms folic acid.
Health food of the present invention can be made into conventional tablet, chewable tablet, soft capsule, hard capsule, pulvis and The peroral dosage forms such as granule.
In the present invention, described auxiliary material be selected from filler (dispersant), suspending agent, wetting agent, adhesive, disintegrant, One or more combination in lubricant, flavouring, stabilizer, embedded object, coating pre-mixing agent, food coloring.
Wherein, filler (dispersant) of the present invention includes starch, soluble starch, dextrin, maltodextrin, Ma Ling Sweet potato starch, cornstarch, wheaten starch, D-mannital, calcium monohydrogen phosphate, calcium phosphate dibasic anhydrous, maltose, xylitol, sorb Sugar alcohol, microcrystalline cellulose, isomaltoketose, milk powder, low-substituted hydroxypropyl cellulose, sucrose, glucose, lactose, pregelatinized starch, One or more of edible vegetable oil, polyethylene glycol etc..
Suspending agent of the present invention including beeswax, insect wax, lecithin, glycerin monostearate, ethyl cellulose etc. its In one or more, described wetting agent includes purified water and ethanol, described adhesive include hydroxypropyl methyl cellulose, PVP, hydroxypropylcellulose, carmethose, starch, methylcellulose, ethyl cellulose, gelatin, polyethylene glycol, pre- glue Change the one of which or several such as starch, sucrose, glucose.
Disintegrant of the present invention includes starch, carboxyrnethyl starch sodium, PVPP, cross-linked carboxymethyl cellulose sodium, low Substitution hydroxypropylcellulose, sodium acid carbonate and citric acid etc. it is therein one or more, described lubricant includes magnesium stearate, hard Resin acid, talcum powder, silica, hydrogenated vegetable oil, polyethylene glycol, lauryl sodium sulfate, Compritol 888 ATO, stearic richness horse Sour sodium etc. it is therein one or more.
Flavouring of the present invention it is therein a kind of including Fruit powder, flavoring essence, high sweetener, acid etc. or Several, described Fruit powder includes orange powder, lemon powder, cherry powder, apple powder, strawberry powder, strawberry powder, kiwi fruit powder, tangerine powder, sand Spine fruit powder, green plum fruit powder, mango fruit powder, mulberry powder, hawthorn fruit powder, watermelon fruit powder, pineapple fruit powder, blueberry powder, honey peach Fruit powder, "Hami" melon fruit powder, grape fruit powder, vanilla fruit powder, pomegranate fruit powder, rose fruit powder etc. it is therein one or more.
Flavoring essence of the present invention include vanilla, orange flavor, milk flavour, flavoring apple essence, grape essence, Strawberry essence, flavoring pineapple essence, peach flavor, Hami melon essence, lemon extract, cherry essence, sweet corn flavor, banana incense Essence, grape essence, grape essence, flavoring rose essence, blackcurrant essence, green apple essence, mango essence, blue or green mango essence, orange Essence, fragrant citrus essence, pyrus nivalis essence, strawberry essence, green plum essence, blueberry flavor, red bayberry essence, shaddock essence, flavoring pineapple essence, Guava essence, passion fruit essence, Chinese grooseberry essence, cherry essence, kiwi flavor, watermelon essence, pawpaw essence, "Hami" melon Essence, durian essence, lychee flavor, hawthorn essence, olive essence, flavoring mulberry essence etc. it is therein one or more.
High sweetener of the present invention includes Sucralose, Aspartame, mogroside, neotame, stevioside, institute The acid stated includes citric acid, citric acid, malic acid, lactic acid, tartaric acid and fumaric acid, and described food coloring includes caramel Color, Gardenia Yellow, curcumin and chlorophyll, chilli orange, capsanthin, red, carmine Grape Skin and its aluminum lake, sunset yellow and its Aluminum lake, light blue and its aluminum lake, indigo and its aluminum lake, beet red, natural amaranth, gardenia blue, plant carbon black, iron oxide Black, iron oxide red, black soya bean are red, quinoline yellow, lycopene, Monascus color, yellow ferric oxide, cacao pigment, safflower yellow, monascus yellow pigment Deng one or more.
Stabilizer of the present invention includes vitamin E, dibutyl hydroxy toluene (BHT), butylated hydroxy anisole (BHA), vitamin C, described embedded object includes beta-schardinger dextrin, alpha-cyclodextrin, gamma-cyclodextrin, dextrin, starch, edible denaturation Starch, sucrose, maltodextrin, gum arabic etc. it is therein one or more.
The vitamin of health food screening function collaboration of the present invention carries out scientific composition, so that it is guaranteed that the work(of product Effect, by supplementing optimal dose vitamin A, folic acid, vitamin B12(3 kinds of vitamins that teenager easily lacks), prevent teenager Visual impairment, and anaemia can be prevented, promote brain intelligence and nerve, skeletal system development, strengthen memory, collaboration promotion is in Hebetic teenagers healthy growth.
The vitamin A entitled retinol of chemistry, orally easily absorbs, and is mainly stored in liver, is in constituting cellula visualis The constituent of rhodopsin.There is photopigment in cellula visualis, that is, feel the rhodopsin of dim light and the visual purple indigo plant of sense high light Matter, the former is made up of opsin with retinol.Retinol is discharged by liver, and retina is transported to through blood, participates in photochemistry anti- Should;If vitamin A (retinol) is not enough, rhodopsin regeneration is slow and incomplete, the extension of dark adaptation recovery time, can when serious Produce yctalopia.Vitamin A or growth vitamin, are epithelial cell parts, can be caused when not enough epithelial atrophy, Keratinization or mucilage cell stop secretion, and xerophthalmia can be caused when serious.Therefore, replenishing vitamins A is played and is maintained normal vision anti- The eye comprehensive health-care effect such as dry eyes and keratomalacia, protection eyesight, should be prevented.Vitamin A is also required bone cell metabolism institute Material, maintains normal skeleton development, promotes bone, dental health growth, and bone growth exception and body can be caused during shortage Growth retardation.Additionally, vitamin A improves body's immunity by adjusting cell, humoral immunity, may be huge with enhancing Phagocyte and the vigor of NK and change that lymphocyte growth, differentiation are relevant, this is undoubtedly conducive to improving blue or green lacking The disease resistance in year.
Folic acid belongs to B family vitamin, is the required material of body cell growth and breeding.Folic acid is through dihyrofolate reductase And vitamin B12Catalysis after form tetrahydrofolic acid, the latter and various one carbon units (including-CH3、-CH2,-CHO etc.) be combined into Tetrahydrofolic acid class coenzyme, transmits one carbon unit, participates in many important reactions and nucleic acid synthesis etc. in vivo.Folic acid deficiency can cause to take off Oxygen ribonucleic acid (DNA) dyssynthesis, and then cell division, breeding be obstructed, and hemopoietic system is influenceed earliest, makes DNA in red blood cell Synthesis is not enough, triggers megaloblastic anemia.MTHFR (MTHFR) gene pleiomorphism may cause me Relative deficiency of the state crowd to folic acid Utilization ability:MTHFR is that 5,10- methylene tetrahydrofolates are reduced to 5-methyltetrahydrofolate Key enzyme, be remarkably decreased enzymatic activity if gene mutation, it is 5-methyltetrahydrofolate to influence the activation of exogenous folic acid, and then Influence one carbon unit transmission.MTHFR C677T have three kinds of genotype, i.e. homozygous wildtype (CC), heterozygous (CT) and homozygosis prominent Modification (TT), TT type enzymatic activitys only have CC types 30%.Population of China TT genotype frequencies average 23.2%, are significantly higher than American-European state Family, the custom of high-temperature cooking vegetables in addition, folic acid deficiency rate (65%) is apparently higher than American-European countries.
Vitamin B12Exist in the form of coenzyme, the utilization rate of folic acid can be strengthened, both combine, along with vitamin A Material necessary to be also generation red blood cell, three collectively promotes development and the maturation of red blood cell, ensures that body hematopoiesis function is normal, So as to prevent anaemia, improve teenager's passive protective physical fitness.Additionally, vitamin B12With folic acid to maintaining central nervous system function just Often also play an important role:Normal methylation reaction is the material base that nervous function is played, and SAM is big The important donor of intracerebral methyl (- CH3), as described above, these methyl and other one carbon units are all (to need dimension life by folic acid transmission Plain B12Auxiliary), they are the important source materials of neurotransmitter synthesis.Research discovery, folic acid or vitamin B12Shortage causes height Plasma homocysteine, relevant with cognitive disorder, its deeper mechanisms is in fact that methylation reaction is damaged.Vitamin B12To nerve System also has trophism, participates in a kind of synthesis of lipoprotein in nerve fiber, has elimination have the fidgets, focus on, increasing The function with the sense of equilibrium is recalled in hypermnesia.In a word, vitamin B12Promotion juvenile intelligence, nervous system development can be cooperateed with folic acid.
Health food of the present invention, has auxiliary protection to teenager's eyesight, hemopoietic system and intelligence development, promotes Effect or healthcare function, are a kind of better, more accurately vitamin nutritional supplements compared with existing product.Tie below Embodiment is closed to be further described embodiments of the present invention.
Brief description of the drawings
Fig. 1 is health food wet granulation technology flow chart of the present invention;
Fig. 2 is health food vertical compression process route chart of the present invention;
Fig. 3 is health food embedding+vertical compression process route chart of the present invention.
Specific embodiment
Embodiment 1:The tablet of health food of the present invention is prepared (1000 amounts)
Formula:
Preparation method:Take 50% ethanol solution of PVP K30 and prepare composite adhesives, then vitamin A is added into adhesive In stir, it is standby.Separately take vitamin B12, folic acid, Sucralose mix with pregelatinized starch, sieve, add milk fragrant Essence, carboxyrnethyl starch sodium, dextrin mixing, addition prepare containing vitamin A adhesive softwood, the granulation of 24 mesh sieves, 55 DEG C dry Dry 2h, 24 mesh sieve whole grains add magnesium stearate mixing, compressing tablet.Pre-mixing agent will be coated and be configured to solution, plain piece is coated, that is, be obtained The tablet of health food of the present invention.
Health food obtained in the present embodiment is taken, according to the Ministry of Public Health《Health food is checked and assessment technique specification》Evaluation Method carries out animal function test and Toxicological evaluation experiment.
Animal contractile studies show:This health food can be obviously improved retinol and folate level, reduction in blood Plasma Homocysteine, alleviate related vitamin lack animal pathological symptom, to animal dark adaptation, intellection and Hemopoietic system has auxiliary promotion functions.
Embodiment 2:The soft capsule of health food of the present invention is prepared (1000 amounts)
Formula:
Preparation method:By beeswax add soybean oil in, 50 DEG C heating, dissolve beeswax, place to room temperature, take vitamin A, Folic acid, vitamin B12Suspension is made in addition soybean oil, it is standby.Separately take gelatin, purified water, burnt sugar coloring, P-hydroxybenzoic acid Ester is configured to glue, and obtained suspended matter is made into soft capsule with pellet press pelleting, through shaping, after washing ball and dried process, i.e., The soft capsule of health food of the present invention is obtained.
Embodiment 3:Health food hard capsule of the present invention is prepared (1000 amounts)
Formula:
Preparation method:Folic acid is mixed with 20% microcrystalline cellulose, is sieved, add vitamin dry powder, 5- methyl tetrahydrochysenes Folic acid mixes, and the raw mixture of gained is mixed with the microcrystalline cellulose equal increments of surplus, adds lactose, stearic acid Magnesium mixes, and is then filled using Autocapsulefillingmachine, and health food of the present invention is obtained after polished treatment Hard capsule.
Embodiment 4:The granule of health food of the present invention is prepared (1000 deal)
Formula:
Preparation method:Sucrose was crushed into 100 mesh sieves standby;Take 50% ethanol solution of PVP K30 and be configured to bonding Agent, then will be stirred in vitamin A addition adhesive, it is standby.Separately take vitamin B12, folic acid mix with sucrose, sieve, then add Enter apple powder, flavoring apple essence, carboxyrnethyl starch sodium, maltodextrin mixing, it is soft containing vitamin A adhesive system that addition is prepared Material, the granulation of 24 mesh sieves, 55 DEG C dry 2h, and 24 mesh sieve whole grains are obtained the granule of health food of the present invention.
Embodiment 5:The chewable tablets of health food of the present invention is prepared (1000 amounts)
Formula:
Preparation method:Take 60% ethanol solutions of Hydroxypropyl methylcellulose E5 and prepare composite adhesives, then vitamin A is added viscous Stirred in mixture, it is standby.Separately take vitamin B12, folic acid mix with microcrystalline cellulose, sieve, add stevioside, lemon Essence, milk powder, xylitol mixing, what addition was prepared contains vitamin A adhesive softwood, the granulation of 24 mesh sieves, 55 DEG C of dryings 2h, 24 mesh sieve whole grains add magnesium stearate mixing, and compressing tablet is the chewable tablets that health food of the present invention is obtained.

Claims (7)

1. a kind of health food for having auxiliary protection or facilitation to teenager's eyesight, hemopoietic system and intelligence development, by tieing up Raw element A, folic acid, vitamin B12And the acceptable auxiliary material composition of health food.
2. health food according to claim 1, it is characterised in that:The vitamin A content is 250~800 μ g, preferably 600~800 μ g;The folate content is 400~800 μ g, preferably 400~600 μ g;The vitamin B12Content is 5~20 μ g, It is preferred that 5~10 μ g.
3. health food according to claims 1 to 2, it is characterised in that:Described folic acid includes folic acid, 5- methyl tetrahydrochysenes Folic acid, formyl tetrahydrofolic acid, folinic acid, Calcium Levofolinate etc., i.e., including artificial synthesized and plant extract source various shapes Formula folic acid.
4. health food according to claims 1 to 3, it is characterised in that:Described auxiliary material be selected from filler (dispersant), Wetting agent, adhesive, disintegrant, lubricant, flavouring, food coloring, stabilizer, embedded object, coating pre-mixing agent etc. are therein One or more combination.
5. health food according to claim 4, it is characterised in that:Described filler (dispersant) includes starch, paste Essence, maltodextrin, farina, cornstarch, D-mannital, calcium monohydrogen phosphate, calcium phosphate dibasic anhydrous, maltose, xylose Alcohol, D-sorbite, microcrystalline cellulose, isomaltoketose, milk powder, low-substituted hydroxypropyl cellulose, sucrose, glucose, pregelatinated form sediment Powder, edible vegetable oil, polyethylene glycol etc. it is therein one or more;Described suspending agent includes:Beeswax, insect wax, lecithin, list Tristerin, ethyl cellulose etc. it is therein one or more.Described flavouring includes Fruit powder, flavoring essence, height Times sweetener, acid etc. it is therein one or more.Described Fruit powder include orange powder, lemon powder, cherry powder, apple powder, The one kind therein such as strawberry powder, kiwi fruit powder, tangerine powder, seabuckthorn fruit powder, green plum fruit powder, mango fruit powder, mulberry powder, hawthorn fruit powder Or it is several.
6. health food according to claims 1 to 5, it is characterised in that:Described health food is prepared to oral system Agent.
7. health food according to claim 6, it is characterised in that:Described oral formulations include conventional tablet, chew Tablet, soft capsule, hard capsule, pulvis and granule.
CN201710032788.8A 2017-01-18 2017-01-18 One kind is applied to teen-age health food Pending CN106820157A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107822011A (en) * 2017-09-28 2018-03-23 黑龙江绿知都生物科技开发有限公司 A kind of children's intelligence development blueberry composite chewable tablet
CN113796524A (en) * 2020-06-15 2021-12-17 郭旭明 Folic acid betaine composite powder and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107822011A (en) * 2017-09-28 2018-03-23 黑龙江绿知都生物科技开发有限公司 A kind of children's intelligence development blueberry composite chewable tablet
CN113796524A (en) * 2020-06-15 2021-12-17 郭旭明 Folic acid betaine composite powder and preparation method thereof

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Application publication date: 20170613