CN1067253C - External preparation of compound sweet wormwood oil - Google Patents
External preparation of compound sweet wormwood oil Download PDFInfo
- Publication number
- CN1067253C CN1067253C CN94103007A CN94103007A CN1067253C CN 1067253 C CN1067253 C CN 1067253C CN 94103007 A CN94103007 A CN 94103007A CN 94103007 A CN94103007 A CN 94103007A CN 1067253 C CN1067253 C CN 1067253C
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- Prior art keywords
- extract
- external preparation
- sweet wormwood
- described external
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 240000000011 Artemisia annua Species 0.000 title claims abstract description 6
- 235000001405 Artemisia annua Nutrition 0.000 title claims abstract description 5
- 150000001875 compounds Chemical class 0.000 title abstract description 4
- 239000000284 extract Substances 0.000 claims abstract description 19
- 239000000758 substrate Substances 0.000 claims abstract description 4
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 9
- 241000180649 Panax notoginseng Species 0.000 claims description 9
- IPQKDIRUZHOIOM-UHFFFAOYSA-N Oroxin A Natural products OC1C(O)C(O)C(CO)OC1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 IPQKDIRUZHOIOM-UHFFFAOYSA-N 0.000 claims description 8
- IKIIZLYTISPENI-ZFORQUDYSA-N baicalin Chemical compound O1[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 IKIIZLYTISPENI-ZFORQUDYSA-N 0.000 claims description 8
- 229960003321 baicalin Drugs 0.000 claims description 8
- AQHDANHUMGXSJZ-UHFFFAOYSA-N baicalin Natural products OC1C(O)C(C(O)CO)OC1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 AQHDANHUMGXSJZ-UHFFFAOYSA-N 0.000 claims description 8
- 229930191701 arteannuin Natural products 0.000 claims description 7
- 229960004191 artemisinin Drugs 0.000 claims description 7
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 claims description 5
- CUCUKLJLRRAKFN-UHFFFAOYSA-N 7-Hydroxy-(S)-usnate Chemical compound CC12C(=O)C(C(=O)C)C(=O)C=C1OC1=C2C(O)=C(C)C(O)=C1C(C)=O CUCUKLJLRRAKFN-UHFFFAOYSA-N 0.000 claims description 5
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 claims description 5
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 claims description 5
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 claims description 5
- PTPHDVKWAYIFRX-UHFFFAOYSA-N Palmatine Natural products C1C2=C(OC)C(OC)=CC=C2C=C2N1CCC1=C2C=C(OC)C(OC)=C1 PTPHDVKWAYIFRX-UHFFFAOYSA-N 0.000 claims description 5
- 229940100243 oleanolic acid Drugs 0.000 claims description 5
- QUCQEUCGKKTEBI-UHFFFAOYSA-N palmatine Chemical compound COC1=CC=C2C=C(C3=C(C=C(C(=C3)OC)OC)CC3)[N+]3=CC2=C1OC QUCQEUCGKKTEBI-UHFFFAOYSA-N 0.000 claims description 5
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 claims description 5
- 229940004858 usnic acid Drugs 0.000 claims description 5
- ICTZCAHDGHPRQR-UHFFFAOYSA-N usnic acid Natural products OC1=C(C)C(O)=C(C(C)=O)C2=C1C1(C)C(O)=C(C(=O)C)C(=O)C=C1O2 ICTZCAHDGHPRQR-UHFFFAOYSA-N 0.000 claims description 5
- WEYVVCKOOFYHRW-UHFFFAOYSA-N usninic acid Natural products CC12C(=O)C(C(=O)C)=C(O)C=C1OC1=C2C(O)=C(C)C(O)=C1C(C)=O WEYVVCKOOFYHRW-UHFFFAOYSA-N 0.000 claims description 5
- 229930187998 Dihydroarteannuin Natural products 0.000 claims description 3
- 241001597008 Nomeidae Species 0.000 claims description 2
- 229960000981 artemether Drugs 0.000 claims description 2
- YBHILYKTIRIUTE-UHFFFAOYSA-N berberine Chemical compound C1=C2CC[N+]3=CC4=C(OC)C(OC)=CC=C4C=C3C2=CC2=C1OCO2 YBHILYKTIRIUTE-UHFFFAOYSA-N 0.000 claims description 2
- 229940093265 berberine Drugs 0.000 claims description 2
- QISXPYZVZJBNDM-UHFFFAOYSA-N berberine Natural products COc1ccc2C=C3N(Cc2c1OC)C=Cc4cc5OCOc5cc34 QISXPYZVZJBNDM-UHFFFAOYSA-N 0.000 claims description 2
- 239000000287 crude extract Substances 0.000 claims description 2
- SXYIRMFQILZOAM-HVNFFKDJSA-N dihydroartemisinin methyl ether Chemical compound C1C[C@H]2[C@H](C)CC[C@H]3[C@@H](C)[C@@H](OC)O[C@H]4[C@]32OO[C@@]1(C)O4 SXYIRMFQILZOAM-HVNFFKDJSA-N 0.000 claims description 2
- 238000009472 formulation Methods 0.000 claims description 2
- ZISJLHQNEVGTIU-RFEYTNPVSA-M sodium 4-oxo-4-[[(1R,4S,5R,8S,9R,10S,12R,13R)-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-yl]oxy]butanoate Chemical compound [Na+].C[C@@H]1CC[C@H]2[C@@H](C)[C@H](OC(=O)CCC([O-])=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4 ZISJLHQNEVGTIU-RFEYTNPVSA-M 0.000 claims description 2
- 239000002075 main ingredient Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 6
- 239000002552 dosage form Substances 0.000 abstract description 4
- 230000001737 promoting effect Effects 0.000 abstract description 4
- 206010007247 Carbuncle Diseases 0.000 abstract description 3
- 201000009053 Neurodermatitis Diseases 0.000 abstract description 3
- 239000006071 cream Substances 0.000 abstract description 3
- 239000000839 emulsion Substances 0.000 abstract description 3
- 238000005469 granulation Methods 0.000 abstract description 3
- 230000003179 granulation Effects 0.000 abstract description 3
- 239000000865 liniment Substances 0.000 abstract description 3
- 229940040145 liniment Drugs 0.000 abstract description 3
- 239000000829 suppository Substances 0.000 abstract description 3
- 206010003399 Arthropod bite Diseases 0.000 abstract description 2
- 201000004624 Dermatitis Diseases 0.000 abstract description 2
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract description 2
- 244000131316 Panax pseudoginseng Species 0.000 abstract description 2
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 239000000499 gel Substances 0.000 abstract description 2
- 230000001338 necrotic effect Effects 0.000 abstract description 2
- 230000008961 swelling Effects 0.000 abstract description 2
- 239000003440 toxic substance Substances 0.000 abstract description 2
- 241001480035 Epidermophyton Species 0.000 abstract 1
- 241000207929 Scutellaria Species 0.000 abstract 1
- 230000000740 bleeding effect Effects 0.000 abstract 1
- 231100001231 less toxic Toxicity 0.000 abstract 1
- 231100000167 toxic agent Toxicity 0.000 abstract 1
- 239000003921 oil Substances 0.000 description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 229930182470 glycoside Natural products 0.000 description 6
- 150000002338 glycosides Chemical class 0.000 description 6
- 238000003756 stirring Methods 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000001035 drying Methods 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000002674 ointment Substances 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 description 2
- 208000002474 Tinea Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000004568 cement Substances 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 241001407408 Berberis fortunei Species 0.000 description 1
- 241000717739 Boswellia sacra Species 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000004863 Frankincense Substances 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 241001057584 Myrrha Species 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 241000893966 Trichophyton verrucosum Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 210000003022 colostrum Anatomy 0.000 description 1
- 235000021277 colostrum Nutrition 0.000 description 1
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229960000935 dehydrated alcohol Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229960002179 ephedrine Drugs 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 229960004756 ethanol Drugs 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 229960003444 immunosuppressant agent Drugs 0.000 description 1
- 230000001861 immunosuppressant effect Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- -1 patch Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000005325 percolation Methods 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 238000004537 pulping Methods 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a compound external preparation which is prepared by taking an extract of a natural plant sweet wormwood as a main component. The external preparation of the invention is mainly prepared from the following components of 0.5-10ml of sweet wormwood oil, 0.5-3g of pseudo-ginseng extract and 0.1-2g of scutellaria extract, and is added with a substrate to prepare 100ml of a pharmaceutically acceptable external preparation. The preparation has effects of removing necrotic tissue, promoting granulation, clearing heat, eliminating dampness, removing toxic substance, stopping bleeding, and promoting blood circulation, can be used for treating neurodermatitis, carbuncle swelling (suppurative dermatitis), epidermophyton, dermatozoon and mosquito bite, has definite curative effect and less toxic and side effects, and can be made into various dosage forms and specifications, such as liniment, emulsion, patch, pellicle, gel, suppository, cream, etc.
Description
The present invention relates to a kind of extract by the natural plants Herba Artemisiae Annuae is the compound external-use preparation that main component is made.
Herba Artemisiae Annuae has another name called Herba Artemisiae annuae, according to TCM Document record Herba Artemisiae Annuae bitter in the mouth cold in nature, cure mainly various skin diseases such as scabies scabies crust is itched, malignant boil, modern medicine proves that its volatile oil has better antibacterial activity, pathogenic bacterium, fungus also there is inhibitory action, clinical various dermatosiss such as neurodermatitis, tinea, carbuncle, furuncle, dermatozoon etc. of being used for the treatment of, existing dosage form has liniment, ointment, cream.The present employed single preparations of ephedrine that is, dosage form is less, and abnormal smells from the patient, zest are big, use inconveniently, and required dosage is big.
Purpose of the present invention is intended to overcome the deficiencies in the prior art, and a kind of convenience, effective Herba Artemisiae Annuae oil compound external-use preparation are provided.
Compounded sweet wormwood oil preparation for external use of the present invention is mainly by following composition Herba Artemisiae Annuae oil 0.5-10ml, Radix Notoginseng extract 0.5-3g, Radix Scutellariae extract 0.1-2g, and adding substrate is made 100ml pharmaceutically can be by the exterior-applied formulation that is subjected to.
Be principal agent with Herba Artemisiae Annuae oil eliminating turbid pathogen with aromatics, removing heat from blood granulation promoting in the prescription of the present invention, be aided with the Radix Scutellariae heat-clearing and toxic substances removing, the pseudo-ginseng blood-circulation-invigovating blood stasis dispelling, reducing swelling and alleviating pain, hemostasis, also can add arteannuin or derivatives thereof 0.1-1g among the above-mentioned side, Rhizoma Coptidis (or Cortex Phellodendri, Mahonia fortunei (Lindl.) Fedde, huangteng) extract 0.1-0.8g, oleanolic acid 0.2-5g, usnic acid 0.1-0.5g, Radix Angelicae Sinensis, Olibanum, Myrrha carry thing and get that each is an amount of.Arteannuin and derivant are mainly arteannuin, dihydroarteannuin, Artemether, sodium artesunate etc., and these materials have effects such as antifungal, immunosuppressant; Rhizoma Coptidis extract is useful commercial berberine or palmatine replacement also.Radix Notoginseng extract in the side is for being the crude extract or the extract of main component with the arasaponin, and Radix Scutellariae extract also can be the commodity baicalin for being the extract of main component with the baicalin.
Preparation removing the necrotic tissue and promoting granulation of the present invention, heat clearing and damp drying, detoxifcation, stop blooding, invigorate blood circulation, can be used for neurodermatitis, carbuncle (suppurative dermatitis), epidermis ringworm, dermatozoon and mosquito bite through clinical verification, determined curative effect, toxic and side effects is few, and can make multiple dosage form and specification, as put system, Emulsion, patch, membrane, gel, suppository, ointment, cream etc. on the skin.
Embodiment:
1, get Herba Artemisiae Annuae oil 5ml, the thick glycoside 1g of Radix Notoginseng, baicalin 0.2g, oleanolic acid 0.2g, usnic acid 0.1g, palmatine 0.1g, DMSO20ml, propylene glycol 50ml, dehydrated alcohol 25ml makes liniment 100ml.
2, get Herba Artemisiae Annuae oil 6ml, the thick glycoside 2g of Radix Notoginseng, Radix Scutellariae glycoside 1g, oleanolic acid 1g, usnic acid 0.3g, palmatine 0.4g adds arabic gum and disperses, and adds the 10ml distilled water again, stir the milky colostrum, thin up is to 200ml, packing promptly gets the Emulsion finished product.
3, get lanoline 5g, vaseline is heated to molten in right amount, adds Herba Artemisiae Annuae oil 8ml, the thick glycoside 1.5g of Radix Notoginseng, and baicalin 0.5g, oleanolic acid 2.5g adds the liquid paraffin wax again to 100g, stirs, and cooling promptly gets ointment.
4, it is an amount of to get PVA, with 85% ethanol percolation, weighs after the drying, makes abundant expansion with distilled water immersion, heat to make and be dissolved into pulpous state, again CMC and PGP are soaked back heating in water bath dissolving pulping, mix with the PVA slurry, stir evenly, add glycerol and Tween 80, stir rubber cement (A).The dry pulp adding distil water is soaked, stir and make pulp, add Herba Artemisiae Annuae oil 1ml, the thick glycoside 2g of Radix Notoginseng, baicalin 1g, usnic acid 0.2g, arteannuin 0.2g and foaming agent, mixing get rubber cement (B).
A, B are merged, mix thoroughly, be paved into the paster of certain specification with shop cloth device, drying below 60 ℃, repaste one deck PVB makes double-layer paster, drying, packing, promptly gets patch.
5, get glycerol, gelatin, water and be made into substrate in 70: 20: 10 ratio, add Herba Artemisiae Annuae oil 4ml after the heat fused, Radix Notoginseng essence glycoside 0.8g, baicalin 2g, palmatine 0.5g, dihydroarteannuin 0.3g, mix thoroughly, insulation makes into aqueous, pours in the bolt mould that was coated with white oil, cooling is wipeed off, takes out packing and promptly gets suppository.
Claims (7)
1, a kind of compounded sweet wormwood oil preparation for external use, it is characterized in that mainly containing following composition: Herba Artemisiae Annuae oil 0.5-10ml, Radix Notoginseng extract 0.5-3g, Radix Scutellariae extract 0.1-2g, add substrate and make the pharmaceutically acceptable exterior-applied formulation of 100ml, described Radix Notoginseng extract is for being the crude extract or the extract of Main Ingredients and Appearance with the arasaponin, and described Radix Scutellariae extract is for being the extract of main component with the baicalin.
2,, it is characterized in that also containing arteannuin or derivatives thereof 0.1-1g according to the described external preparation of claim 1.
3,, it is characterized in that arteannuin and derivant are mainly arteannuin, dihydroarteannuin, Artemether, sodium artesunate according to the described external preparation of claim 2.
4,, it is characterized in that also containing oleanolic acid 0.2-5g according to the described external preparation of claim 1.
5,, it is characterized in that also containing berberine or palmatine 0.1-0.8g according to the described external preparation of claim 1.
6,, it is characterized in that also containing usnic acid 0.1-0.5g according to the described external preparation of claim 1.
7,, it is characterized in that Radix Scutellariae extract can substitute with baicalin according to the described external preparation of claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN94103007A CN1067253C (en) | 1994-03-16 | 1994-03-16 | External preparation of compound sweet wormwood oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN94103007A CN1067253C (en) | 1994-03-16 | 1994-03-16 | External preparation of compound sweet wormwood oil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1108549A CN1108549A (en) | 1995-09-20 |
| CN1067253C true CN1067253C (en) | 2001-06-20 |
Family
ID=5030893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN94103007A Expired - Lifetime CN1067253C (en) | 1994-03-16 | 1994-03-16 | External preparation of compound sweet wormwood oil |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1067253C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE517738C2 (en) * | 2000-11-22 | 2002-07-09 | Denovastella Ab | Preparations for the treatment of allergic symptoms containing oils from Artemisia and the procedure for its preparation |
| CN102552451A (en) * | 2011-12-31 | 2012-07-11 | 王志远 | Artemisinin wine and preparation method thereof |
| CN109875945A (en) * | 2019-04-12 | 2019-06-14 | 广东新南方青蒿药业股份有限公司 | Careless oil of a kind of sweet wormwood hundred and its preparation method and application |
| CN110664858B (en) * | 2019-11-11 | 2022-04-12 | 云南青之浩生物科技有限公司 | Artemisia annua extract composition for skin, product and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1078645A (en) * | 1993-04-20 | 1993-11-24 | 谢民福 | Antiphlogistic oil for external use and compound method thereof |
-
1994
- 1994-03-16 CN CN94103007A patent/CN1067253C/en not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1078645A (en) * | 1993-04-20 | 1993-11-24 | 谢民福 | Antiphlogistic oil for external use and compound method thereof |
Non-Patent Citations (5)
| Title |
|---|
| 《中成药》1990,12(9) 1990.10.1 刘彦明，黄芩甙作紫外光吸收刘试制多效防晒液 * |
| 《临床皮肤科杂志》1985,14(6) 1985.7.1 方大定，抗***反应中草药的研究进展 * |
| 《四川中医》1985,3(3) 1985.4.1 冯文宇，青蒿油资料神经性皮炎 * |
| 《河北中医》1986,(4) 1986.4.1 郭玉波，复方狼毒胶囊资料银屑病250例观察 * |
| 《河北中医》1986,(4) 1986.4.1 郭玉波，复方狼毒胶囊资料银屑病250例观察;《临床皮肤科杂志》1985,14(6) 1985.7.1 方大定，抗***反应中草药的研究进展;《四川中医》1985,3(3) 1985.4.1 冯文宇，青蒿油资料神经性皮炎;《中成药》1990,12(9) 1990.10.1 刘彦明，黄芩甙作紫外光吸收刘试制多效防晒液 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1108549A (en) | 1995-09-20 |
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