CN106693096A - Hemodialysis device and method capable of online measuring urea clearance index - Google Patents
Hemodialysis device and method capable of online measuring urea clearance index Download PDFInfo
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- CN106693096A CN106693096A CN201611262537.0A CN201611262537A CN106693096A CN 106693096 A CN106693096 A CN 106693096A CN 201611262537 A CN201611262537 A CN 201611262537A CN 106693096 A CN106693096 A CN 106693096A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
- A61M1/1656—Apparatus for preparing dialysates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
- G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
- G01N27/06—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a liquid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3327—Measuring
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Abstract
Disclosed is a hemodialysis device and method capable of online measuring urea clearance index. The hemodialysis device comprises a balance cavity, a dialyzer, a first liquid suction pump and a second liquid suction pump, the first liquid suction pump is used for pumping in liquid B, the second liquid suction pump is used for pumping in liquid A, the liquid B and the liquid A are mixed to form dialysate, the dialysate after entering the balance cavity enters the dialyzer through an inlet end of the dialyzer to interact with blood of a patient, and dialysis waste liquid is generated after interaction and flows out of the dialyzer through an outlet end of the same; a first conductivity measurer is arranged on a pipeline between the balance cavity and the inlet end of the dialyzer and used for measuring a conductivity value of the dialysate before interaction, and a second conductivity measurer is arranged at the outlet end of the dialyzer and used for measuring a conductivity value of the dialysis waste liquid after interaction; the hemodialysis device further comprises a calculation module, and the calculation module calculates the urea clearance index on the basis of a difference value between the conductivity value of the dialysate before interaction and the conductivity value of the dialysis waste liquid after interaction.
Description
Technical field
The present invention relates to dialysis machine technical field, more particularly to a kind of blood for being capable of on-line determination Urea clearance index
Dialysis apparatus.
Background technology
One main purpose of blood purification treatment is just that instead of the kidney of patient, completes the removing of toxin, and its is medium and small
The elimination effect of molecule is most important, therefore, if in accurately holding each therapeutic process, patient's small molecule clearance rate, then
This therapeutic effect can effectively be assessed.In multiple small molecule compositions, the elimination effect of urea is particularly important, it may be said that urine
The clearance rate of element directly represents small molecule clearance rate, directly represents the effect of this time treatment.
Accordingly, it would be desirable to develop a kind of new haemodialysis equipment, the clearance rate of the urea of blood purification treatment can be entered
Row is determined, so that it is determined that Urea clearance index.
The content of the invention
For technical problem present in prior art, being capable of on-line determination urea it is an object of the invention to provide one kind
Remove the haemodialysis equipment of index.
To achieve the above object, technical scheme is as follows：
A kind of haemodialysis equipment for being capable of on-line determination Urea clearance index, including counter balance pocket, dialyzer, the first imbibition
Pump and the second suction pumps, the first suction pumps are used to pump into B liquid, and the second suction pumps are used to pump into A liquid, and B liquid is mixed to form with A liquid
Analysis liquid, and into through entering dialyzer by the entrance point of dialyzer, being handed over the blood of patient in dialyzer after counter balance pocket
Mutually, dialysis waste liquid is produced after interaction and is flowed out from dialyzer via the dialyzer port of export；
Wherein, the first conductivity measuring appliance is provided with the pipeline between counter balance pocket and the entrance point of dialyzer, for surveying
The conductance angle value of the dialyzate before amount interaction；The second conductivity measuring appliance is provided with the port of export of dialyzer, for measuring interaction
The conductance angle value of dialysis waste liquid afterwards；Haemodialysis equipment also includes measuring and calculating module, and measuring and calculating module is based on the dialyzate before interaction
Conductance angle value with interact after dialysis waste liquid conductance angle value difference calculate Urea clearance index.
The beneficial effects of the present invention are haemodialysis equipment of the invention is by the first conductivity measuring appliance and the second electricity
Degree of leading measuring appliance measures the conductance angle value of the dialysis flowed back into dialyzer and from dialyzer respectively, determines and calculate Na ions
Clearance rate, because Na ions are coincide very much by the transhipment situation of pellicle and urea, therefore, can be by the clearance rate of Na ions
Urea clearance is similar to, so as to obtain Urea clearance index, the elimination effect of small molecule is embodied, blood purification treatment effect is understood
The situation of fruit.
Brief description of the drawings
Fig. 1 is electrolyte clearance rate and urea clearance curve map.
Fig. 2 is the connection signal of the haemodialysis equipment for being capable of on-line determination Urea clearance index of one embodiment of the invention
Figure.
Fig. 3 shows for the connection of the haemodialysis equipment for being capable of on-line determination Urea clearance index of another embodiment of the present invention
It is intended to.
Fig. 4 is the curve that the conductance angle value that the first conductivity measuring appliance and the second conductivity measuring appliance are measured is changed over time
Figure.
Specific embodiment
Embodying feature of present invention will describe in detail in the following description with the exemplary embodiments of advantage.It should be understood that this
Invention can have various changes in different embodiments, and it does not all depart from protection scope of the present invention, and theory therein
Bright and accompanying drawing is inherently to be illustrated as being used, and is not used to the limitation present invention.
The haemodialysis equipment of the present embodiment is the equipment that the patients such as uremia carry out daily treatment, is not emergency treatment equipment,
The general therapeutic time was at 4 hours or so.
First, it is an object of the invention to on-line determination Urea clearance index, its principle is as follows：
As shown in figure 1, over the course for the treatment of, Na ions are coincide very much by the transhipment situation and urea of pellicle, are such as schemed
In show, Na ions clearance rate and urea clearance meet 1:1 relation, for example, at 37 DEG C, Na ion clearance rates are
1.94*10-5, urea clearance is 2.20*10-5.Urea clearance index urea.If it is possible to accurately hold therapeutic process
Middle Na ions just can obtain content of the urea in current blood samples of patients by the transhipment situation of pellicle, bulk registration,
Just it is known that this time in therapeutic process, the urea of patient removes situation, and then deduces small molecule elimination effect and treatment
Effect.
Based on above-mentioned principle, the present invention provides a kind of haemodialysis equipment for being capable of on-line determination Urea clearance index, its
Structure is as follows：
As shown in Fig. 2 the main working parts of the haemodialysis equipment of the embodiment of the present invention include heating chamber 2, gear pump
31st, the 32, first suction pumps 51, the second suction pumps 52 and counter balance pocket 7.In addition, the dialysis machine of the embodiment of the present invention has reverse osmosis water
Water inlet 1, discard solution discharge port 8 and the dialyzer interface for connecting dialyzer 40.The dialysis machine of the embodiment of the present invention can also
Including dialyzer 40.
It is connected to after dialyzer interface by dialyzer 40, the waste liquid side of dialyzer 40 is connected with second gear pump 32,
Second gear pump 32 is connected to the left chamber side of counter balance pocket 7.The entrance point and the port of export of dialyzer 40 are connected to the first conductance
The degree conductivity measuring appliance 42 of measuring appliance 41 and second, the first conductivity measuring appliance 41 is connected to the right chamber side of counter balance pocket 7, for measuring
Into the conductance angle value of the dialyzate of dialyzer 40, i.e. dialyzate interacted with blood samples of patients before conductance angle value；Second conductivity
Measuring appliance 42 is connected to the left chamber side of counter balance pocket 7, the conductance angle value for measuring the dialysis waste liquid flowed back to from dialyzer 40, i.e. thoroughly
Analyse the conductance angle value after liquid is interacted with blood samples of patients.
It is connected to after dialyzer interface by dialyzer 40, the waste liquid side of dialyzer 40 is connected with second gear pump 32,
Second gear pump 32 is connected to the left chamber side of counter balance pocket 7.
First suction pumps 51 are used to pump into B liquid, and the second suction pumps 52 are used to pump into A liquid.First suction pumps 51 and second are inhaled
Liquid pump 52 can be stepper motor driven piston pump.
In the haemodialysis equipment course of work of the embodiment of the present invention, reverse osmosis water enters from reverse osmosis water water inlet 1, passes through
After first gear pump 31, the first suction pumps 51 and the second suction pumps 52 are sequentially passed through, the liquid drawn with above-mentioned suction pumps mixes,
Configuration is good in counter balance pocket 7 and flows out for mixed dialyzate, is interacted with the blood of patient by dialyzer 40 so that patient's
Blood completes purification, and waste liquid is discharged again by second gear pump 32 after moving to counter balance pocket 7.With this repeatedly, until treatment knot
Beam.
Fig. 3 shows the haemodialysis equipment that can automatically adjust potassium concentration of another embodiment of the present invention, wherein,
Counter balance pocket 7 is the core component of the dialysis machine of the embodiment of the present invention, and its concrete structure and operation principle are as follows.
Counter balance pocket 7 is the cavity that volume is fixed, and centre is divided into equal two parts by a tunic, and film can freely in chamber
It is mobile in vivo.Every side of cavity film all connects two valves, an inflow for being used for liquid, an outflow for being used for liquid.
Generally in use, the penstock that enters of side is opened, and flowing water Valve is closed, and the flowing water Valve of opposite side is opened, and enters water valve
Door is closed.When the liquid for entering water side is full of whole counter balance pockets 7, the liquid of opposite side is emptied completely.In the embodiment of the present invention
Dialysis machine counter balance pocket 7, be made up of counter balance pocket 71 and 72 liang of counter balance pocket set counter balance pockets, each counter balance pocket is respectively provided with left and right two
Cavity, the side where therefore, it can two left chambers is called the left chamber side of counter balance pocket 7, and the side where two right chambers is balance
The right chamber side in chamber 7.8 valves 1A, 1B, 2A, 2B, 3A, 3B, 4A, 4B are respectively placed in the both sides of counter balance pocket 71 and counter balance pocket 72,
The valve of the left chamber of right chamber, the left chamber of counter balance pocket 71, the right chamber of counter balance pocket 72 and the counter balance pocket 72 of counter balance pocket 71 is respectively, its
In " A " represent into penstock, " B " represent flowing water Valve.
In the haemodialysis equipment course of work of the embodiment of the present invention, reverse osmosis water enters from reverse osmosis water water inlet 1, passes through
After first gear pump 31, mix in proportion with B liquid through the first suction pumps 51, then through the second suction pumps 52 with and A liquid proportionally
Mixing, the right chamber of counter balance pocket 71 is entered by valve 1A, while the waste liquid of the left chamber of counter balance pocket 71 is discharged by valve 2B；It is same in this
When, the dialyzate for having configured flows out from the right chamber of counter balance pocket 72 by valve 3B, is interacted with the blood of patient by dialyzer 40, makes
The blood for obtaining patient completes purification, and waste liquid by second gear pump 32, moves to the left chamber of counter balance pocket 72 again.Switching counter balance pocket, instead
Enter the right chamber of counter balance pocket 72 by valve 3A after infiltration and A liquid, the mixing of B liquid, while left chamber waste liquid is discharged by valve 4B；It is flat
The weighing apparatus right chamber dialyzate of chamber 71 enters the left chamber of counter balance pocket 71 by second gear pump 32, completes the saturating of 7 one cycle periods of counter balance pocket
Analysis treatment.With this repeatedly, until treatment end.
Hereinafter, to how on-line determination Urea clearance index is described in detail.
The haemodialysis equipment of on-line determination Urea clearance index of the invention is measured by the first conductivity measuring appliance 41
Into the conductance angle value of the dialyzate of dialyzer 40, the dialysis flowed out from dialyzer 40 is measured by the second conductivity measuring appliance 42
The conductance angle value of waste liquid.The two conductance angle value that will be measured compare, so as to calculate the elimination effect of Na ions, so as to calculate
Go out the elimination effect of urea.
Conductance angle value is essentially Na ion concentrations in dialyzate, therefore, the conductance of the measurement of the first conductivity measuring appliance 41
Angle value be essentially into dialyzer 40 dialyzate Na ion concentrations, i.e. dialyzate interacted with blood samples of patients before conductance
Angle value；The conductance angle value of the measurement of the second conductivity measuring appliance 42 is essentially the Na ions of the dialysis waste liquid flowed back to from dialyzer 40
Concentration, i.e. dialyzate interacted with blood samples of patients after conductance angle value.For theory, and the dialyzate before blood samples of patients interaction
Middle Na ion concentrations are low, and Na ion concentrations are high in blood samples of patients, therefore, Na ion concentrations can be because dispersion in dialysis waste liquid
And raise, specific elevated amount just can indication go out transhipment situation of the Na ions by pellicle, hold dialyzate conductivity and
The difference of dialysis waste liquid conductivity just can learn transhipment situation of the Na ions by pellicle.
Due to by conductivity measuring appliance conductance angle value measured directly it is smaller, change it is smaller, thus it can be difficult to hold
Firmly small change, therefore, in one embodiment, the first plunger displacement pump 51 and the second plunger displacement pump 52 can be improved, so as to improve concentration
The suction ratio of liquid A and concentrate B, thus improve the dialyzate conductance angle value into dialyzer.
Current urea clearance K can be calculated according to following formula one.Wherein, Qd is dialysate flow, and it is to set
Fixed treatment parameter, cdi is the conductance angle value of the dialyzer entrance point measured by the first conductivity measuring appliance 41, and cdo is by
The conductance angle value of the dialyzer port of export of the measurement of two conductivities measurement 42.Cdi1 and cdo1 is the first plunger displacement pump 51 and second of raising
The conductance angle value at the time point before plunger displacement pump 52, i.e. valley value, cdi2 and cdo2 are raising the first plunger displacement pump 51 and the second post
Conductance angle value after plug pump 52, i.e. crest value.The present apparatus in use, the first conductivity measuring appliance 41 and the second conductivity
Measurement 42 is constantly detected, when needing to carry out urea clearance measure, raising the first plunger displacement pump 51 and the second plunger displacement pump 52
Soakage so that the first conductivity measuring appliance 41 and the second conductivity measurement 42 detected value there is crest, that is, rise peak S1
With rising peak S2.As shown in figure 4, rise peak S1 there is obvious difference with peak S2 is risen, and there is delayed phenomenon, i.e.
Rise peak S2 and lag behind rising peak S1.The present apparatus will be extracted and rise peak S1 and rise the corresponding conductance angle value of peak S2, i.e. cdi2 with
cdo2。
According to the setting of doctor, measurement (such as 30 minutes) is carried out once every time rating, in measurement process
The first plunger displacement pump 51 and the second plunger displacement pump 52 are improved, the one-shot measurement time is shorter, about within 1 minute, the imbibition ratio of raising
10% or so, because time of measuring is short, increase rate is not too high, therefore, although the rising of dialyzate conductivity can be caused,
But do not interfere with therapeutic effect.
After calculating K values, Kt/V, i.e. Urea clearance index can be calculated, wherein t is from starting treatment to this measurement
Time, V is body surface area.
Wherein, body surface area V can be calculated according to equation below two, and formula two is also called Watson formula, its with
The height of patient, sex, age, body weight are information-related.
Formula two:
Thus, it is possible to calculate the Kt/V values of patient, as Urea clearance index.
In sum, haemodialysis equipment of the invention is by the first conductivity measuring appliance and the second conductivity measuring appliance point
The conductance angle value of the dialysis flowed back into dialyzer and from dialyzer is not measured, determines and calculate the clearance rate of Na ions, by
It is coincide very much by the transhipment situation and urea of pellicle in Na ions, therefore, the clearance rate of Na ions can be similar to urea
Clearance rate, so as to obtain Urea clearance index, embodies the elimination effect of small molecule, understands the situation of blood purification treatment effect.
Artisan will appreciate that of the invention disclosed in appended claims of the invention not departing from
The change made in the case of scope and spirit and retouching, belong within scope of the claims of the invention.
Claims (8)
1. a kind of haemodialysis equipment for being capable of on-line determination Urea clearance index, including counter balance pocket, dialyzer, the first suction pumps
And second suction pumps, the first suction pumps are used to pump into B liquid, and the second suction pumps are used to pump into A liquid, and B liquid is mixed to form dialysis with A liquid
Liquid, and into through entering dialyzer by the entrance point of dialyzer, being interacted with the blood of patient in dialyzer after counter balance pocket,
Dialysis waste liquid is produced after interaction and is flowed out from dialyzer via the dialyzer port of export；
Wherein, the first conductivity measuring appliance is provided with the pipeline between counter balance pocket and the entrance point of dialyzer, is handed over for measuring
The conductance angle value of the dialyzate before mutually；The second conductivity measuring appliance is provided with the port of export of dialyzer, after measuring interaction
The conductance angle value of dialysis waste liquid；Haemodialysis equipment also includes measuring and calculating module, and measuring and calculating module is based on the electricity of the dialyzate before interaction
The difference measuring and calculating Urea clearance index of the conductance angle value of the dialysis waste liquid after leading angle value and interacting.
2. the haemodialysis equipment of on-line determination Urea clearance index is capable of as claimed in claim 1, wherein, by improving the
The soakage of one plunger displacement pump and the second plunger displacement pump so that the first conductivity measuring appliance and the detected value of the second conductivity measurement occur
Crest, measuring and calculating module calculates urea clearance based on below equation, wherein, Qd is dialysate flow, and cdi1 is the first plunger
Before the soakage of pump and the second plunger displacement pump is enhanced, the measured value of the first conductivity measuring appliance, cdo1 is the first plunger displacement pump and the
Before the soakage of two plunger displacement pumps is enhanced, the measured value of the second conductivity measuring appliance, cdi2 is the first plunger displacement pump and the second plunger
After the soakage of pump is enhanced, the crest value of the measurement of the first conductivity measuring appliance, cdo2 is the first plunger displacement pump and the second plunger
After the soakage of pump is enhanced, the crest value of the measurement of the second conductivity measuring appliance
。
3. the haemodialysis equipment of on-line determination Urea clearance index is capable of as claimed in claim 2, wherein, calculate module base
Urea clearance index is calculated in below equation：
Urea clearance index=Kt/V
Wherein, t is the time measured to this since dialysis treatment, and V is body surface area, the height of body surface area and patient,
Sex, age, body weight are information-related.
4. the haemodialysis equipment of on-line determination Urea clearance index is capable of as claimed in claim 3, wherein, the second conductivity
The time lag that the crest value of the measurement of measuring appliance occurs is when the crest value of the measurement of the first conductivity measuring appliance occurs
Between.
5. the haemodialysis equipment of on-line determination Urea clearance index is capable of as claimed in claim 4, wherein, urea is removed and referred to
Several time of measuring is 1-2 minutes, and the soakage of the first plunger displacement pump and the second plunger displacement pump is improved in time of measuring, by improving
The soakage of the first plunger displacement pump and the second plunger displacement pump so that the suction ratio of B liquid and A liquid improves 10%.
6. a kind of method of on-line determination Urea clearance index, for haemodialysis equipment, wherein, haemodialysis equipment includes flat
Weighing apparatus chamber, dialyzer, the first suction pumps and the second suction pumps, the first suction pumps are used to pump into B liquid, and the second suction pumps are used to pump into A
Liquid, B liquid and A liquid are mixed to form dialyzate, and into after counter balance pocket through entering dialyzer by the entrance point of dialyzer, with dialyzer
The blood of interior patient is interacted, and dialysis waste liquid is produced after interaction and is flowed out from dialyzer via the dialyzer port of export；Flat
Pipeline between weighing apparatus chamber and the entrance point of dialyzer is provided with the first conductivity measuring appliance, for measuring the dialyzate before interaction
Conductance angle value；The second conductivity measuring appliance is provided with the port of export of dialyzer, the conductance for measuring the dialysis waste liquid after interaction
Angle value, wherein, the method for on-line determination Urea clearance index includes：
Conductance angle value based on the dialyzate before interaction with interact after dialysis waste liquid conductance angle value difference measuring and calculating urea it is clear
Except index.
7. the method for on-line determination Urea clearance index as claimed in claim 6, wherein, by improving the first plunger displacement pump and the
The soakage of two plunger displacement pumps so that the first conductivity measuring appliance and the second conductivity measurement detected value there is crest, based on
Lower formula calculates urea clearance, wherein, Qd is dialysate flow, and cdi1 is the suction of the first plunger displacement pump and the second plunger displacement pump
Before amount is enhanced, the measured value of the first conductivity measuring appliance, cdo1 is that the soakage of the first plunger displacement pump and the second plunger displacement pump is carried
Gao Qian, the measured value of the second conductivity measuring appliance, cdi2 be the first plunger displacement pump and the second plunger displacement pump soakage be enhanced after before,
The crest value of the measurement of the first conductivity measuring appliance, cdo2 be the first plunger displacement pump and the second plunger displacement pump soakage be enhanced after,
The crest value of the measurement of the second conductivity measuring appliance
。
8. the method for on-line determination Urea clearance index as claimed in claim 7, wherein, urea is calculated based on below equation clear
Except index：
Urea clearance index=Kt/V
Wherein, t is the time measured to this since dialysis treatment, and V is body surface area.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611262537.0A CN106693096A (en) | 2016-12-30 | 2016-12-30 | Hemodialysis device and method capable of online measuring urea clearance index |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611262537.0A CN106693096A (en) | 2016-12-30 | 2016-12-30 | Hemodialysis device and method capable of online measuring urea clearance index |
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| CN201611262537.0A Pending CN106693096A (en) | 2016-12-30 | 2016-12-30 | Hemodialysis device and method capable of online measuring urea clearance index |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108379678A (en) * | 2018-01-31 | 2018-08-10 | 东南大学 | A kind of hemo system dialysis-effect detecting system and its control method |
| CN111225693A (en) * | 2017-10-17 | 2020-06-02 | 日机装株式会社 | Blood purification device |
| CN113694280A (en) * | 2021-09-02 | 2021-11-26 | 山东威高血液净化制品股份有限公司 | Method for monitoring toxin content distribution in-vitro dialyzer in real time |
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|---|---|---|---|---|
| CN1092324A (en) * | 1993-03-17 | 1994-09-21 | 信东化学工业股份有限公司 | The apparatus and method of instant proper dialysis |
| EP0986410B1 (en) * | 1997-06-02 | 2006-03-29 | Gambro Lundia AB | Device for calculating dialysis efficiency |
| CN1678360A (en) * | 2002-09-05 | 2005-10-05 | 甘布罗伦迪亚股份公司 | Sontrol apparatus and control method for a blood treatment equipment |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111225693A (en) * | 2017-10-17 | 2020-06-02 | 日机装株式会社 | Blood purification device |
| CN108379678A (en) * | 2018-01-31 | 2018-08-10 | 东南大学 | A kind of hemo system dialysis-effect detecting system and its control method |
| CN108379678B (en) * | 2018-01-31 | 2020-11-20 | 东南大学 | Hemodialysis machine dialysis effect detection system and control method thereof |
| CN113694280A (en) * | 2021-09-02 | 2021-11-26 | 山东威高血液净化制品股份有限公司 | Method for monitoring toxin content distribution in-vitro dialyzer in real time |
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