CN106689222A - Traditional Chinese medicine disinfectant for preventing aquaculture bacteriosis and preparation method of disinfectant - Google Patents

Traditional Chinese medicine disinfectant for preventing aquaculture bacteriosis and preparation method of disinfectant Download PDF

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Publication number
CN106689222A
CN106689222A CN201510778550.0A CN201510778550A CN106689222A CN 106689222 A CN106689222 A CN 106689222A CN 201510778550 A CN201510778550 A CN 201510778550A CN 106689222 A CN106689222 A CN 106689222A
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China
Prior art keywords
chinese medicine
bacteriosis
preparation
disinfectant
parts
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Pending
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CN201510778550.0A
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Chinese (zh)
Inventor
刘鼎阔
刘芳
王立红
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Dingzheng Animal Pharmaceutical Tianjin Co Ltd
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Dingzheng Animal Pharmaceutical Tianjin Co Ltd
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Priority to CN201510778550.0A priority Critical patent/CN106689222A/en
Publication of CN106689222A publication Critical patent/CN106689222A/en
Pending legal-status Critical Current

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  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Farming Of Fish And Shellfish (AREA)

Abstract

The invention relates to a traditional Chinese medicine disinfectant for preventing aquaculture bacteriosis and a preparation method of the disinfectant. The traditional Chinese medicine disinfectant is prepared from, by weight, 1-5 parts of lonicera japonica, 1-10 parts of rhizoma coptidis, 1-5 parts of herba houttuyniae and 1-5 parts of radix bupleuri. The traditional Chinese medicine disinfectant has obvious bacteriostatic and bactericidal effects, is fast to absorb, good in curative effect, low in toxic and side effect and free of drug residue, and meets the requirements of safe veterinary drugs and animal-derived food safety guarantees and is ideal.

Description

A kind of Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis and preparation method thereof
Technical field
The invention belongs in Chinese medicine antiseptic field, especially a kind of preventing and treating aquaculture bacteriosis Medicine disinfectant and preparation method thereof.
Background technology
In recent years, because the residual problem of medicine causes impact to Export of Chinese Aquatic Products, government is to whole fishing medicine Market has carried out large-scale rectification, and large quantities of aquatic products disabling medicines, such as chloramphenicol, furans are disclosed in succession Cuo ketone, malachite green, pentachloro- phenolic acid sodium etc., special aquatic products animal due to its economic worth is high and with compared with Under big export market, therefore joint efforts in every respect.The use of forbidden drug has been obtained well Control, and in the breeding process of conventional fish, the generation of bacteriosis is more frequent, and scale occurs Also than larger.But limited by its commodity value and export market, cultivation dealer still often selects Conventional method is treated, even with some illegal drugs, such as chloramphenicol, furans Cuo ketone, malachite Green, pentachloro- phenolic acid sodium etc. controls disease.Such prevention and controls not only make the quality of aquatic products be subject to serious Influence, and the long-term use of medicine can also produce the stronger resistance to the action of a drug, be that the usage amount of medicine is increased; And the breeding wastewater discharged produces direct or indirect pollution to natural environment, to the sustainable development of society Exhibition brings serious negative effect, therefore, in the disease control of conventional fish, exploration is promoted in some Medicine novel formulation just seems particularly important.
The content of the invention
It is an object of the invention to overcome the deficiencies in the prior art, there is provided one kind preventing and treating aquaculture is bacillary Chinese medicine antiseptic of disease and preparation method thereof medicine disinfectant, the active ingredient of the Chinese medicine antiseptic can have Effect suppress and kill bacterium, have no toxic side effect, will not more produce medicament residue, it is easy to use, cost compared with It is low, it is not likely to produce drug resistance.
It is another object of the present invention to provide a kind of disinfection of Chinese drug for preventing and treating aquaculture bacteriosis The preparation method of agent.
The present invention is achieved through the following technical solutions:
It is a kind of prevent and treat aquaculture bacteriosis Chinese medicine antiseptic, the component of the Chinese medicine antiseptic and its Percentage by weight is:
Honeysuckle 1-5 parts;
Coptis 1-10 parts;
Cordate houttuynia 1-5 parts;
Radix bupleuri 1-5 parts.
A kind of preparation method of the Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis, its preparation method bag Include following steps:
(1) honeysuckle, the coptis, cordate houttuynia and radix bupleuri is weighed respectively according to weight proportion to be crushed;
(2) by mixture, decocted three times after soaking one hour, each amount of water is medicinal material total amount It is 8-120 times, each to decoct 1-1.5 hours, collecting decoction, it is more than 1.05 to be concentrated into density, filtering, filter Liquid merges, and ethanol is added slowly with stirring after cooling, ethanol content is reached 40%, stands 12 hours, Filtration, it is ethanol content to reclaim ethanol, that is, obtain the Chinese medicine antiseptic finished product of aquaculture bacteriosis.
It is according to claim 2 it is a kind of prevent and treat aquaculture bacteriosis Chinese medicine antiseptic and its Preparation method, it is characterised in that:Described preparation process needs ethanol alcohol precipitation to dispel impurity.
Advantages of the present invention and beneficial effect are:
1. Flos lonicerae is contained in the component of the Chinese medicine antiseptic of this preventing and treating aquaculture bacteriosis, There is its effective ingredient good resisting pathogenic microbes to act on.To various pathogens such as staphylococcus aureus, Hemolytic streptococcus, Escherichia coli, shigella dysenteriae, comma bacillus, typhoid bacillus, paratyphosum Bacterium etc. There is certain effect of restraining.
2. Chinese Medicine Cortex Phellodendri is contained in the component of the Chinese medicine antiseptic of this preventing and treating aquaculture bacteriosis, it is yellow Even antibiotic effective ingredient is jamaicin, can effective bacteria growing inhibiting, killing bacterium, cost is relatively low, It is not likely to produce drug resistance.
3. Chinese Medicinal Houttuynia Cordata Thunb is contained in the component of the Chinese medicine antiseptic of this preventing and treating aquaculture bacteriosis, A kind of yellow oil is raised from cordate houttuynia, to various microorganisms (especially saccharomycete and mould) There is inhibitory action, streptococcus, staphylococcus aureus, Bacillus influenzae, micrococcus catarrhalis to hemolytic, Pneumococcus has obvious inhibitory action.Also there is effect to Escherichia coli, shigella dysenteriae, typhoid bacillus, Artificial synthesized decanoylacetaldehyde sodium hydrosulfite addition product is referred to as the decanoy acetaldehyde of synthesis.
4. bupleurum Chinese, bavin are contained in the component of the Chinese medicine antiseptic of this preventing and treating aquaculture bacteriosis Hu water extract has significant inhibitory action to staphylococcus aureus, typhoid bacillus;To being caused by typhoid bacillus The chmice acute abdominal cavity infection death rate have obvious reducing effect, and this effect with the increase of drug dose There is a certain degree of enhancing.
5. this Chinese medicine antiseptic has very strong killing to various pathogens, free virus, obstinate bacteria etc. Effect, and to improving the sanitary standard of cultured product, reply is closed trade green barrier and is very beneficial, more Green ecological cultivation opens a new situation.
5. the active ingredient of Chinese medicine antiseptic of the present invention can effectively suppress and kill bacterium, have no toxic side effect, Medicament residue will not be more produced, easy to use, cost is relatively low, be a kind of preventing and treating for being not likely to produce drug resistance The Chinese medicine antiseptic of aquaculture bacteriosis.
Specific embodiment
The present invention is described in further detail by following examples.It should be noted that:Following embodiments are explanations Property, it is not limited, it is impossible to limit protection scope of the present invention with following embodiments.
Raw material honeysuckle, the coptis, cordate houttuynia and radix bupleuri in the present invention can commercially be bought Arrive.
Embodiment 1
A kind of Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis and preparation method thereof, the wherein Chinese medicine Disinfectant component and its weight are honeysuckle 30g, coptis 20g, cordate houttuynia 30g, radix bupleuri 20g.
A kind of Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis, be the step of its preparation method:
(1) honeysuckle, the coptis, cordate houttuynia and radix bupleuri is weighed respectively according to weight proportion to be crushed;
(2) by mixture, decocted three times after soaking one hour, each amount of water is medicinal material total amount It is 8-120 times, each to decoct 1-1.5 hours, collecting decoction, it is more than 1.05 to be concentrated into density, filtering, filter Liquid merges, and ethanol is added slowly with stirring after cooling, ethanol content is reached 40%, stands 12 hours, Filtration, it is ethanol content to reclaim ethanol, that is, obtain the Chinese medicine antiseptic finished product of aquaculture bacteriosis.
Embodiment 2
A kind of Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis and preparation method thereof medicine disinfectant, its In the Chinese medicine antiseptic component and its weight be honeysuckle 25g, coptis 30g, cordate houttuynia 25g, radix bupleuri 20g.
The step of its preparation method, is with embodiment 1.
Embodiment 3
A kind of Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis and preparation method thereof medicine disinfectant, its In the Chinese medicine antiseptic component and its weight be honeysuckle 35g, coptis 20g, cordate houttuynia 15g, radix bupleuri 30g.
The step of its preparation method, is with embodiment 1.
Embodiment 4
A kind of Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis and preparation method thereof medicine disinfectant, its In the Chinese medicine antiseptic component and its weight be honeysuckle 40g, coptis 15g, cordate houttuynia 20g, radix bupleuri 25g.
The step of its preparation method, is with embodiment 1.
A kind of Chinese medicine antiseptic for preventing and treating aquaculture bacteriosis and preparation method thereof medicine disinfectant is in system Application in standby preventing and treating aquaculture bacterium, parasite or virus drugs and preparing aquaculture product Plant the application in external sterilization and breeding water body disinfecting drug.
Clinical practice
In March, 2015~2015 year April carries out product release experiment in 3, Jiangsu Province aquaculture base, There is the plant of obvious bacteriosis in the aquatic products of this 5 aquaculture bases, by product of the present invention Used by every mu of rice of 300~500ml/, once a day, after continuously using 3 days, the water in breeding water body The product phenomena of mortality disappear, and recover normal using breeding water body after 5 days.The experiment shows that the present invention can have Bacteriosis in effect preventing and treating breeding water body, and the immunocompetence of aquatic products in breeding water body can be increased, Efficient reachable more than 98%.

Claims (3)

1. it is a kind of prevent and treat aquaculture bacteriosis Chinese medicine antiseptic, it is characterised in that:Should The component and its percentage by weight of Chinese medicine antiseptic be:
Honeysuckle 1-5 parts;
Coptis 1-10 parts;
Cordate houttuynia 1-5 parts;
Radix bupleuri 1-5 parts.
2. a kind of a kind of Chinese medicine for preventing and treating aquaculture bacteriosis as claimed in claim 1 Its preparation method of disinfectant, it is characterised in that:The step of preparation method, is as follows:
(1) weighing honeysuckle, the coptis, cordate houttuynia and radix bupleuri respectively according to weight proportion is carried out Crush;
(2) by mixture, decocted three times after soaking one hour, each amount of water is medicine 8-120 times of material total amount, each to decoct 1-1.5 hours, collecting decoction, it is 1.05 to be concentrated into density More than, filtering, filtrate merges, and ethanol is added slowly with stirring after cooling, makes ethanol content 40% is reached, 12 hours are stood, filtration, it is ethanol content to reclaim ethanol, that is, obtain aquatic products Cultivate the Chinese medicine antiseptic finished product of bacteriosis.
3. a kind of Chinese medicine for preventing and treating aquaculture bacteriosis according to claim 2 disappears Toxic agent and preparation method thereof, it is characterised in that:Described preparation process needs ethanol alcohol precipitation to dispel Impurity.
CN201510778550.0A 2015-11-13 2015-11-13 Traditional Chinese medicine disinfectant for preventing aquaculture bacteriosis and preparation method of disinfectant Pending CN106689222A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107646882A (en) * 2017-11-08 2018-02-02 广西沙田仙人滩农业投资有限公司 A kind of aquaculture pond disinfectant
CN107691485A (en) * 2017-08-21 2018-02-16 长沙新气象自动化技术有限公司 A kind of pond Chinese herbal medicinal bactericide and its manufacture craft
CN113384639A (en) * 2021-06-28 2021-09-14 成都农业科技职业学院 Chinese herbal medicine preparation for preventing and treating bacterial diseases of aquatic animals and preparation and using methods thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107691485A (en) * 2017-08-21 2018-02-16 长沙新气象自动化技术有限公司 A kind of pond Chinese herbal medicinal bactericide and its manufacture craft
CN107646882A (en) * 2017-11-08 2018-02-02 广西沙田仙人滩农业投资有限公司 A kind of aquaculture pond disinfectant
CN113384639A (en) * 2021-06-28 2021-09-14 成都农业科技职业学院 Chinese herbal medicine preparation for preventing and treating bacterial diseases of aquatic animals and preparation and using methods thereof

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Application publication date: 20170524