CN106689176B - It is a kind of using industrial lignin as Prochloraz microcapsules of wall material and preparation method thereof - Google Patents

It is a kind of using industrial lignin as Prochloraz microcapsules of wall material and preparation method thereof Download PDF

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CN106689176B
CN106689176B CN201611093274.5A CN201611093274A CN106689176B CN 106689176 B CN106689176 B CN 106689176B CN 201611093274 A CN201611093274 A CN 201611093274A CN 106689176 B CN106689176 B CN 106689176B
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prochloraz
microcapsules
lignin
industrial lignin
wall material
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CN106689176A (en
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邱学青
钱勇
谭善元
杨东杰
楼宏铭
庞煜霞
刘伟峰
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South China University of Technology SCUT
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South China University of Technology SCUT
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules

Abstract

The invention belongs to technical field of pesticide, disclose a kind of using industrial lignin as Prochloraz microcapsules of wall material and preparation method thereof.Preparation method of the present invention is the following steps are included: 1~20 parts by weight industrial lignin is dissolved in the pH of 100~200 parts by weight to filter out insoluble matter after adjusting pH value of solution to 6~10, obtaining industrial lignin solution in 12 aqueous solution by (1)；(2) the industrial lignin solution of 10~50 parts by weight steps (1) is mixed with the Prochloraz of 2~20 parts by weight, ultrasonic radiation 10s~5min under the power of 200~1500W obtains Prochloraz microcapsule suspensions.Prochloraz microcapsules of the invention have good anti-light solution and sustained release performance, and for drugloading rate close to 100%, encapsulation rate is higher than 95%；It containing a large amount of phenyl ring and phenolic group structure, can effectively remove the free radical in material, prevent raw medicine by the ultraviolet light photodissociation in sunlight using industrial lignin as wall material.

Description

It is a kind of using industrial lignin as Prochloraz microcapsules of wall material and preparation method thereof
Technical field
The invention belongs to technical field of pesticide, in particular to it is a kind of using industrial lignin as the Prochloraz microcapsules of wall material and Preparation method.
Background technique
China is pesticide producing big country and using big country, and nearly 5 years national pesticide dosages are all at 310,000 tons or so, preparation 100 More ten thousand tons, pesticide utilization rate is 35% or so.Chinese pesticide dosage has been higher by 5 times of world standard, and " control amount proposes effect " becomes pesticide The requisite measure of zero growth rate.Meanwhile as the development of pollution-less agriculture, especially high poison, persistent pesticide environmental pollution draw Play the common concern of people, to pesticide investment four big changes are occurring for peasant household: pesticide selection from a low price, be mostly used to efficiently, one It is secondary to use transformation, saving labor cost；Pesticide investment from large conventional variety to low toxicity, low-residual, safety, without using wind Danger, the transformation of environment-friendly type kind；Pesticide use is changed from low cost, low put into reasonable cost, best investment；The prevention and control of plant diseases, pest control by Chemical pesticide combines direction transformation to chemical pesticide with biological pesticide.
In recent years, pesticide micro capsule is because many advantages are widely noticed: 1, microcapsule membrane can mutually be separated oily with water phase, right The pesticide activity component of water unstable can be made into microcapsule formulations；2, decomposition and the stream of pesticide caused by light, heat, rainwater etc. are inhibited It loses, improves the stability of medicament itself；3, microcapsules cyst membrane can inhibit the volatility of pesticide, desalinate its original peculiar smell, drop Its low contact toxicity, toxicity on inhalation and phytotoxicity；4, control-release function is introduced, the utilization rate of pesticide is improved, extends its lasting period, subtract The quantity and frequency of Shaoshi medicine improve pesticide to the pressure of environment；It 5, is the optimization of the pesticidal active substance of a variety of different performances Compatibility provides convenient.It is microcapsules by the micron that core material embedding is got up to be formed 1~100 μm by wall material.Microcapsule wall material one As be high molecular polymer, and natural products such as gelatin, chitosan, liposome, Arabic gum etc. because it is from a wealth of sources be easy to get, The advantages such as non-toxic degradable, simple processing, low in cost are also widely used as wall material and prepare microcapsules.
Lignin is the natural polymer that content is only second to cellulose in plant, and the annual whole world is by plant growth It can produce 150,000,000,000 tons of lignin, industrial annual 30000000 tons of generation, but using lignin as microcapsules, especially pesticide The research of microcapsule wall material is very few.Ma Lijie etc., using avermectin as capsule-core, adds using chitosan and sodium lignin sulfonate as capsule material Enter emulsifier, crosslinking agent, agglomerates 15min, crosslinking 1h again, be prepared for microcapsules.Gained blank microcapsules average grain diameter is 5.80 μ M, the drugloading rates of microcapsules are that 12.6% (Ma Lijie, Zhao Jing chitosan/sodium lignin sulfonate complex coacervation prepare biological pesticide Microcapsules Beijing University of Chemical Technology journal, 2006,33 (6): 51-56).This method needs to be added two or more emulsifiers and crosslinking Agent, multiple cohesion and cross-linking process will carry out time-controllable, and the microcapsules rate prepared is very low.Week is refined equal then by by Avermectin After element is impregnated in neopelex electrification, micron order chitosan/wood is prepared for using the method for Self assembly Quality sodium sulfonate microcapsules (Zhou Bin, Zhao Jing LBL self-assembly prepare avermectin microcapsule and its drug release behavior fine chemistry industry, 2008,25 (7): 625-635).Although Self assembly is simple, need to charge in pesticide pretreatment, it is subsequent from group Dress process also needs to introduce chitosan, and the Microcapsules Size of preparation is difficult to control, and pesticide load factor is also relatively low, practical application value Less.Fu Weijin etc. is prepared for wooden using industrial alkali lignin, phenol and formaldehyde as main wall material using reversed emulsion polymerization Plain phenolic aldehyde base avermectin microcapsule, the microcapsules have apparent slow release effect (Fu Weijin, Zhang Shu when content of lignin 50% It is graceful, Mai Jiawen, the preparation of Zhang Qian Lignin phenolic base drug bearing microsphere and sustained release performance polymer material science and engineering, 2012,28(10):117-120.).This method is by lignin and avermectin, formaldehyde, phenol and cetyl trimethyl bromination One pot of hybrid reaction of ammonium, but severe reaction conditions, are easily destroyed the structure of core material avermectin, and raw medicine effective content is caused to drop It is low.Then, Fu Weijin et al. changes technique, and using the performed polymer of urea, formaldehyde and lignin as wall material, addition is dissolved in sapn and chlorine The avermectin of benzene forms lotion, is eventually adding filtration drying in oxalic acid water and obtains the lignin urea urea formaldehyde of embedding avermectin Microcapsules (a kind of preparation method .CN102349509A. of lignin urea-formaldehyde pesticide microcapsule of Fu Weijin, Zhang Shuting).The party Method also needs a large amount of wall materials, and the drugloading rate of pesticide avermectin and encapsulation rate there was only 15~35% and 60 respectively~ 80%, embedding efficiency is lower, is industrially not easily accomplished production.Zhou Mingsong et al. reports a kind of amido with pH responsiveness Lignosulfonates are method (Zhou Mingsong, Xu Ruilin, Qiu Xueqing, Yang Dongjie, the Pang Yu that wall material prepares avermectin microcapsule A kind of application lignin-base wall material of rosy clouds prepares avermectin microcapsule powder and its method .CN 105010362A.).Although the party The drugloading rate and encapsulation rate of method preparation increase, but the lignosulfonates needs used are amination modified, subsequent also to need Crosslinking agent is added to be reacted, entire microcapsules preparation process is still complicated, higher cost.
Currently, the generally existing preparation process of the microcapsules prepared using lignin as main wall material is complicated, pesticide load capacity and The problems such as encapsulation rate is low, and pesticide resolution ratio is high in embedding process, lignin are that unique wall material prepares the research of pesticide micro capsule still It has not seen.
Summary of the invention
In order to overcome the shortcomings and deficiencies of the prior art described above, the primary purpose of the present invention is that providing a kind of with industrial wood Quality is the preparation method of the Prochloraz microcapsules of wall material.The method of the present invention simple process, environmentally protective, low in raw material price, Product drugloading rate and encapsulation rate are high, and sustained release performance is good.
The method of the present invention is mixed using industrial lignin as wall material with oily pesticide Prochloraz, is handled through one step of ultrasonic radiation Stable industrial lignin base Prochloraz microcapsule emulsion can be formed.Wherein, industrial lignin is unique wall material, and Prochloraz is Core material, industrial lignin can emulsify Prochloraz encystation during ultrasonic radiation, and simultaneously free radical occurs for industrial lignin itself Prochloraz microcapsule emulsion is can be obtained through centrifugation washing in crosslinking, the complex microsphere being crosslinked.
Industrial lignin has a large amount of phenyl ring, carbonyl equiconjugate structure, and there are also phenolic hydroxyl group, methoxyl groups etc. to have relatively strong purple The active function groups of outer absorption, and a large amount of existing phenolic hydroxyl groups are capable of forming phenolic under ultrasonic radiation in industrial lignin molecule Free radical promotes industrial lignin that intermolecular cross-linking polymerization occurs.
Another object of the present invention be to provide above method preparation using industrial lignin as the Prochloraz microcapsules of wall material. Prochloraz microcapsules of the invention have good anti-light solution and sustained release performance, and close to 100%, encapsulation rate is higher than drugloading rate 95%.
The purpose of the present invention is realized by following proposal:
It is a kind of using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, comprising the following steps:
(1) 1~20 parts by weight industrial lignin is dissolved in the aqueous solution that the pH of 100~200 parts by weight is 12, is adjusted PH value of solution obtains industrial lignin solution to insoluble matter is filtered out after 6~10；
(2) the industrial lignin solution of 10~50 parts by weight steps (1) is mixed with the Prochloraz of 2~20 parts by weight, Ultrasonic radiation 10s~5min under the power of 200~1500W, obtains Prochloraz microcapsule suspensions.
The industrial lignin can are as follows: soda pulping process (including wood pulp, bamboo pulp, Straw Pulp, reed pulp, bagasse pulp, Chinese alpine rush Slurry, Cotton Pulp) alkali lignin, acid polishing (including wood pulp, bamboo pulp, Straw Pulp, reed pulp, bagasse pulp, Dracaena straw pulp, cotton Pulp) one or more of lignosulfonates, enzymolysis xylogen, organosolv lignin and Milled wood lignin.
In order to further be better achieved the object of the invention, the quality in aqueous solution of industrial lignin described in step (1) Score is preferably 3~10%；The adjusting pH value of solution is preferably adjusted to 7~9.
In order to which the object of the invention is further better achieved, it is preferable to use dilute acid solns for step (1) the adjusting pH value of solution It adjusts, is more preferably adjusted using dilute hydrochloric acid solution.
In order to further be better achieved the object of the invention, industrial lignin solution described in step (2) and Prochloraz Weight ratio is preferably 0.6:1~5:1.
In order to which the object of the invention is further better achieved, the power of ultrasonic radiation described in step (2) is preferably controlled in The time of 500~1000W, the ultrasonic radiation are preferably controlled in 1~3min.
In order to which the object of the invention is further better achieved, the purity of Prochloraz raw medicine used in step (2) is 98%.
In order to which the object of the invention is further better achieved, the Prochloraz microcapsule suspensions being prepared can pass through Extra lignin is removed in centrifugal water washout, obtains Prochloraz microcapsules.
The present invention also provides the above method be prepared using industrial lignin as the Prochloraz microcapsules of wall material, have Good anti-light solution and sustained release performance, for drugloading rate close to 100%, encapsulation rate is higher than 95%.
Compared with similar products, the wall material of capsule of the present invention is from a wealth of sources, low in cost；Wall material is natural polymer, can Natural degradation is waste material；Contain a large amount of phenyl ring and phenolic group structure in wall material molecule, can effectively remove the free radical in material, prevents Only raw medicine is by the ultraviolet light photodissociation in sunlight, and the microcapsules load sharing dose and encapsulation rate of preparation are very high, and sustained release performance is significant.
The present invention compared with the existing technology, have the following advantages and the utility model has the advantages that
1, for preparation method of the present invention without adding emulsifier and crosslinking agent, ultrasonic radiation can guarantee that one step of emulsification and cross linked is complete At simple process, process green, low in cost, product is environment-protecting and non-poisonous；
2, the wall material that preparation method of the present invention uses derives from plant, grows, can be connect to avoid Prochloraz altogether with mankind's symbiosis Other animals and plants are not had toxic action by touching, injury skin；
3, the Prochloraz microcapsules that the present invention is prepared using industrial lignin as wall material, since lignin belongs to natural polymer Son contains a large amount of phenyl ring and phenolic group structure in molecule, can effectively solve Prochloraz raw medicine intolerant to the defect of sunlight photodissociation；
4, microcapsules prepared by the present invention have high drugloading rate and encapsulation rate, and sustained release performance is significant.
5, properties of microcapsules prepared by the present invention is prominent, and preparation is simple, has good prospects for commercial application.
Detailed description of the invention
Fig. 1 is the optical microscope of microcapsules prepared by embodiment 1.
Fig. 2 is cumulative release curve of the microcapsules prepared by embodiment 1 in dissolution medium.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail, and embodiments of the present invention are not limited thereto.
Reagent used in the following example can be obtained from commercial channel.
Embodiment 1
(1) 20g alkali lignin is placed in 250mL beaker, the aqueous dissolution lignin of addition 180g pH12, then plus Enter dilute hydrochloric acid and adjust pH value of solution to after 9, filter out insoluble matter, obtains the alkali lignin aqueous solution that mass fraction is 10%.
(2) take in step (1) alkali lignin aqueous solution 30g obtained mixed with 50g pesticide prochloraz (water-oil factor 0.6: 1), by the ultrasonic echography radiation treatment 3min of power 500W, the suspension containing prochloraz microcapsules is obtained.
(3) suspension centrifuge separation will be obtained in step (2), obtains prochloraz microcapsules lotion, water dispersion is added to obtain miaow Amide microcapsule emulsion.
Embodiment 2
(1) 6g lignosulfonates are placed in 250mL beaker, the aqueous dissolution lignin of 194g pH12 is added, then Dilute hydrochloric acid is added and adjusts pH value of solution to after 7, filters out insoluble matter, obtains the lignin sulfonic acid saline solution that mass fraction is 3%.
(2) take in step (1) lignin sulfonic acid saline solution 50g obtained mixed with 10g pesticide prochloraz (water-oil factor 5: 1), by the ultrasonic echography radiation treatment 1min of power 1000W, the suspension containing prochloraz microcapsules is obtained.
(3) suspension centrifuge separation will be obtained in step (2), obtains prochloraz microcapsules lotion, water dispersion is added to obtain miaow Amide microcapsule emulsion.
Embodiment 3
(1) 15g organosolv lignin is placed in 250mL beaker, the aqueous dissolution lignin of 185g pH12 is added, It adds dilute hydrochloric acid and adjusts pH value of solution to after 8.5, filter out insoluble matter, obtain the organosolv lignin water that mass fraction is 7.5% Solution.
(2) take in step (1) organosolv lignin aqueous solution 50g obtained mixed with 50g pesticide prochloraz (water-oil factor 1: 1), by the ultrasonic echography radiation treatment 2min of power 700W, the suspension containing prochloraz microcapsules is obtained.
(3) suspension centrifuge separation will be obtained in step (2), obtains prochloraz microcapsules lotion, water dispersion is added to obtain miaow Amide microcapsule emulsion.
Embodiment 4
(1) 10g enzymolysis xylogen is placed in 250mL beaker, the aqueous dissolution lignin of 190g pH12 is added, then Dilute hydrochloric acid is added and adjusts pH value of solution to after 8.0, filters out insoluble matter, obtains the enzymolysis xylogen aqueous solution that mass fraction is 5%.
(2) take in step (1) enzymolysis xylogen aqueous solution 50g obtained mixed with 25g pesticide prochloraz (water-oil factor 2: 1), by the ultrasonic echography radiation treatment 1.5min of power 800W, the suspension containing prochloraz microcapsules is obtained.
(3) suspension centrifuge separation will be obtained in step (2), obtains prochloraz microcapsules lotion, water dispersion is added to obtain miaow Amide microcapsule emulsion.
Embodiment 5
(1) 9g Milled wood lignin is placed in 250mL beaker, the aqueous dissolution lignin of addition 191g pH12, then plus Enter dilute hydrochloric acid and adjust pH value of solution to after 8.0, filter out insoluble matter, obtains the Milled wood lignin aqueous solution that mass fraction is 4.5%.
(2) take in step (1) Milled wood lignin aqueous solution 45g obtained mixed with 15g pesticide prochloraz (water-oil factor 3: 1), by the ultrasonic echography radiation treatment 2min of power 600W, the suspension containing prochloraz microcapsules is obtained.
(3) suspension centrifuge separation will be obtained in step (2), obtains prochloraz microcapsules lotion, water dispersion is added to obtain miaow Amide microcapsule emulsion.
Embodiment effect explanation
(1) drugloading rate and encapsulation rate
The drugloading rate and encapsulation rate of microcapsules in each embodiment of table 1
Note: drugloading rate=(raw medicine quality in microcapsules)/(microcapsules gross mass) × 100%；
Contain rate=(microcapsules gross mass) × (drugloading rate)/(microcapsules Central Plains medicine theoretical value) × 100%.
High drugloading rate and encapsulation rate shows the utilization rate that ensure that drug in the lower situation of wall material dosage.It is protecting Under the premise of demonstrate,proving microcapsules quality, the production cost of microcapsules can be greatly reduced in the drugloading rate and encapsulation rate that improve microcapsules. Seen from table 1, the microcapsules prepared in various embodiments of the present invention have high drugloading rate and encapsulation rate, have great cost Advantage.
(2) microcapsules pattern
Fig. 1 is prochloraz microcapsules optical microscope prepared by embodiment 1, and the microcapsule size is uniform, 5 μ of partial size < M is in finely dispersed spherical structure.
(3) sustained release performance
Fig. 2 is cumulative release curve of the prochloraz microcapsules of the preparation of embodiment 1 in 70% methanol aqueous solution.Preceding 20h Rate of release is very fast, but cumulative release amount only has rate of release after 55%, 20h to slow down, and Cumulative release amount is 80% when 150h, and And release is still carrying out, and shows that the Controlled-Release Capability of Microcapsules is good.
Wherein specific step is as follows for release experiment:
A certain amount of microcapsule emulsion is taken, is put into the saturating of molecular cut off 1000 after diluting using 70% methanol aqueous solution It analyses in bag, bag filter is put into equipped with 140mL, in the sealed glass jars of 70% methanol aqueous solution, is put into constant-temperature table, at 25 DEG C And release experiment is carried out under 200rpm speed conditions, 1mL solution measurement wherein prochloraz is taken from vial at regular intervals Content, while supplementing 70% methanol aqueous solution of 1mL and keeping constant volume, and then drawing cumulative release curve.
The above implementation result shows Prochloraz microcapsules prepared by the present invention compared with prior art, has very excellent Slow release effect, while there is high drugloading rate and encapsulation rate, and wall material is from a wealth of sources, technique is extremely simple, cheap Great cost advantage.Because containing a large amount of phenyl ring and phenolic group structure in wall material lignin, there is significant anti-light solution characteristic, therefore It can solve the defect that Prochloraz is degraded vulnerable to sunlight irradiation.Lignin derives from plant, total with the mankind and other animals and plants It is raw long altogether, it is nontoxic, it is green material.Therefore, microcapsules prepared by the present invention have performance more outstanding a little, tool There is good prospects for commercial application.
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment Limitation, other any changes, modifications, substitutions, combinations, simplifications made without departing from the spirit and principles of the present invention, It should be equivalent substitute mode, be included within the scope of the present invention.

Claims (10)

1. a kind of using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, it is characterised in that the following steps are included:
(1) 1~20 parts by weight industrial lignin is dissolved in the aqueous solution that the pH of 100~200 parts by weight is 12, adjusts solution Insoluble matter is filtered out after pH to 6~10, obtains industrial lignin solution；
(2) the industrial lignin solution of 10~50 parts by weight steps (1) is mixed with the Prochloraz of 2~20 parts by weight, 200~ Ultrasonic radiation 10s~5min under the power of 1500W, obtains Prochloraz microcapsule suspensions.
2. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: the industrial lignin are as follows: the alkali lignin of soda pulping process, lignosulfonates, enzymolysis xylogen, the solvent of acid polishing One or more of type lignin and Milled wood lignin.
3. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: mass fraction is 3~10% to industrial lignin described in step (1) in aqueous solution.
4. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: adjusting pH value of solution described in step (1), which refers to, is adjusted to 7~9.
5. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: step (1) the adjusting pH value of solution is adjusted using dilute acid soln.
6. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: step (1) the adjusting pH value of solution is adjusted using dilute hydrochloric acid solution.
7. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: the weight ratio of industrial lignin solution described in step (2) and Prochloraz is 0.6:1~5:1.
8. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: the power of ultrasonic radiation described in step (2) is 500~1000W.
9. according to claim 1 using industrial lignin as the preparation method of the Prochloraz microcapsules of wall material, feature exists In: the time of ultrasonic radiation described in step (2) is 1~3min.
Any one of 10. a kind of using industrial lignin as the Prochloraz microcapsules of wall material, it is characterised in that according to claim 1~9 The preparation method obtains.
CN201611093274.5A 2016-12-02 2016-12-02 It is a kind of using industrial lignin as Prochloraz microcapsules of wall material and preparation method thereof Active CN106689176B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4417916A (en) * 1979-03-26 1983-11-29 Monsanto Company Encapsulation by interfacial polycondensation
CN104365651A (en) * 2014-11-03 2015-02-25 联保作物科技有限公司 Prochloraz microcapsule suspending agent and compound preparation thereof
CN105566929A (en) * 2014-10-31 2016-05-11 韩国科学技术研究院 Lignin microcapsule and method of producing the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4417916A (en) * 1979-03-26 1983-11-29 Monsanto Company Encapsulation by interfacial polycondensation
CN105566929A (en) * 2014-10-31 2016-05-11 韩国科学技术研究院 Lignin microcapsule and method of producing the same
CN104365651A (en) * 2014-11-03 2015-02-25 联保作物科技有限公司 Prochloraz microcapsule suspending agent and compound preparation thereof

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