CN106668524A - Hui nationality traditional Chinese medicine radix scutellariae tablet for treating breast cancer and preparation method thereof - Google Patents
Hui nationality traditional Chinese medicine radix scutellariae tablet for treating breast cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a formula of a Hui nationality traditional Chinese medicine radix scutellariae tablet for treating breast cancer and a preparation method of the Hui nationality traditional Chinese medicine radix scutellariae tablet. The Hui nationality traditional Chinese medicine radix scutellariae tablet is an eco-friendly high-tech traditional Chinese medicine for treating breast cancer and is prepared from traditional Chinese medicines such as scorpion, Chinese gall, fructus trichosanthis and the like according to a certain proportion through material blending, water decoction, extraction, concentration and tabletting. The Hui nationality traditional Chinese medicine radix scutellariae tablet is mainly used for treating breast cancer and also can treat pancreatic cancer, liver cancer, lung cancer, cervical cancer, gastrointestinal cancer and skin cancer. The Hui nationality traditional Chinese medicine radix scutellariae tablet has a moderate taste and a moderate dose. The selected traditional Chinese medicines are proved to be able to treat cancers by the modern medical pharmacology experiments. The Hui nationality traditional Chinese medicine radix scutellariae tablet realizes a very low cost, can thoroughly improve human body functions, can prevent and treat cell cancerization and can restore health.
Description
Technical field
[0001] it is a kind of green high-tech Chinese herbal medicine of prevention and treatment breast carcinoma that Hui ethnic group's baikal skullcap root mammary gland according to the present invention drives cancer piece.The invention further relates to the preparation method of the medicine, belongs to Chinese medicine class.
Background technology
[0002] evidence《China's tumour registration annual report in 2014》Data display, according to China's Life Calculation of 74 years old for each person, the probability that Chinese suffer from malignant tumor in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumor, and tumor has become a kind of common disease in China.The cancer patient of China is about more than 700 ten thousand people at present, and is being increased with the speed of more than 100 ten thousand people every year.And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 25.89% for patient with breast cancer, after occupying 35.23% pulmonary carcinoma.Breast carcinoma is the common cancer that women ranks the first(Breast carcinoma male only accounts for the about 1-2% of the various Cancer Mortalities of whole body, and comparison is rare, and women is then 7-10%,), it is a kind of one of modal malignant tumor for having a strong impact on women's physical and mental health or even threat to life.The people for why suffering from breast cancer at present is more and moreWhy person in middle and old age easily suffer from breast cancerThough the cause of disease is not fully apparent from, many research datas show, the generation of breast carcinoma is removed outside native factor, also relevant with following factors:1. pressure is excessive at heart, it is impossible to discharge emotion.2. viral:Carcinogenecity rna virus may be related to breast carcinoma.3. atypical hyperplasia:There are breast duct and lobule atypical hyperplasia person that the dangerous increase of breast carcinoma occurs.(Note:Said herein is atypical hyperplasia, is not the cyclomastopathy in usual spoken language)4. heredity and family history:Multiple in family is also confirmed in statistics breast carcinoma.With family history of breast cancer(One-level lineal relative suffer from breast cancer)Women, the danger that breast carcinoma occurs is 2-3 times of population.5. trophic factor:High lipid material intake excessively has certain dependency with breast carcinoma.6. long-time stimulus of endogenouss or exogenous estrogen:The activity of estrogen plays an important role to breast carcinoma.Menstruation is risen too early(Less than 12 years old)Or menopause evening(It is later than 55 years old), do not give birth to, late childbirth(First tire is after 35 years old)Or not suckling after fertility, the incidence rate of breast carcinoma is higher etc..
The current western medical treatment of breast carcinoma is mainly surgical operation therapy and radiotherapy.Operative treatment is divided into radical mastectomy, breast carcinoma Super-radical excision, imitative radical correction (modified skinsuture) according to the practical situation of patient again.Radiotherapy is divided into the radiotherapy of preoperative radiation therapy and postoperative irradiation and relapse and metastasis stove again, but no matter which kind of is treated, and all can cause to urge the pain of ruining property and can't ensure to return to one's perfect health to the body and mind of patient.
Breast carcinoma is disease at present compared with refractory more as other cancers, all, but refractory is not represented and cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively Therapeutic Method.Breast carcinoma Chinese traditional treatment happens since time immemorial.Chinese traditional treatment breast carcinoma goes for various each phase cancer with organic conception according to the whole body feature determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of patient.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effects are slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band tumor, and patient is easy to receive and expense is than less expensive.Doctor trained in Western medicine is also considered as Chinese medicine at present can contribute to reducing the toxicity of Radiotherapy chemotherapy, improves cancer related symptoms, improve life quality, extend life cycle as the auxiliary treatment of cancer.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all " compatibility " medicine that function for cancer and effect " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs " are not proved by modern medicine pharmacological evaluation in selected Chinese herbal medicine medical material, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatable poor, high level evidence-based medicine EBM be theoretical and the relative shortage of evidence,Thus the situation for mainly waiting deficiency by rule of thumb for cancer, propose a kind of new dosage and preparation method, there is provided one kind reduces the sickness rate of breast carcinoma from the beginning of prevention, start to slow down its tempo from canceration, start to induce the green high-tech Chinese herbal medicine of its atrophy apoptosis from tumor.Specifically, before the present invention one is particularly suited for use in treatment cancer, atypical hyperplasia is in case its canceration, two is to treat cancer just ulcer, in case which continues to deteriorate, three is to can induce cancerous protuberance atrophy apoptosis into tumor, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to induce self apoptosis of cancerous cell and differentiation to greatest extent, promote cancerous protuberance progressively atrophy.In specific formula, also coordinate determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, according to the Genetic Characteristics of breast carcinoma, belong to stagnation of QI due to depression of the liver, soothing liver-QI for relieving depression, regulating QI to relieve pain;Belong to scorchingly hot to pent up, heat-clearing and toxic substances removing, hard masses softening and resolving;Belong to deficient qi and blood, benefiting qi and nourishing blood, hard masses softening and resolving;Belong to the hepatic and renal YIN deficiency, nourishing kidney-YIN ...
To correct the deficiency of healthy energy interior-deficiency, evil solidifying malicious poly- and internal organs imbalance of YIN and YANG function reduction, adjust and improve the immunologic function of body, to reach the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of carninomatosis treatment, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for patient with breast cancer, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and finally recovers healthy.Thus also select different treatment methods or several method to share particularly Chinese and western medicine to combine the leeway of Comprehensive Treatment application, to obtaining optimum curative effect, easily improve survival rate to consider according to the personal state of an illness, economic situation, personal inclination to patient one.
Technical scheme proposed by the invention is:
It is by made by following weight proportion raw material that Hui ethnic group's baikal skullcap root mammary gland of the first, described prevention and treatment breast carcinoma drives cancer piece:
Radix Scutellariae 9g, Fructus Trichosanthis 15g, Herba Taraxaci 30g, Thallus Laminariae (Thallus Eckloniae) 30g,
Rhizoma Belamcandae 7g, Concha Ostreae 30g, Nidus Vespae 9g, Radix Angelicae Sinensis 11g,
Rhizoma Polygonati Odorati 9g, Rhizoma Atractylodis Macrocephalae 9g, 2 pairs of Bufo siccuss
This side is substantially square for one decoction on the one.In practical application, also the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory can be increased according to the body constitution of patient and conditions“Dialectical compatibility " medicine.
In view of with this, basic side's decoction decoction amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.
2nd, by the preparation method that above-mentioned each raw material makes Chinese medicinal tablet of the present invention it is:
A, extract preparation
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Rhizoma Belamcandae 7g, Rhizoma Atractylodis Macrocephalae 9g, all amplify 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate are standby.
B, second extraction:The 5-7 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted or so half an hour, extraction fluid, pressure filtration, filtrate are standby.
C, third time are extracted:The 3-5 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted 20 minutes or so, extraction fluid, pressure filtration, filtrate are standby.
(2), concentration
The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.
(3), powder processed
Rhizoma Belamcandae 7g, Rhizoma Atractylodis Macrocephalae 9g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.
(5), drying, crushing
The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, is crossed 100 mesh sieves.
(6), pelletize
The spice of mix homogeneously is inserted into pelletize in comminutor.
(7), granulate
The granule for making is carried out into granulate, 35 mesh sieves are crossed.
(8), it is dried
Whole good granule is inserted in heat circulation drying oven, at 80 DEG C, aeration-drying is to moisture < 8%.
(9), tabletting
Magnesium stearate mix homogeneously is added to be placed in tabletting in tablet machine medicine obtained by dry mixed(Also can coating), every 0.5g.
B, packaging
First the tablet for pressing is loaded in vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).
, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Three times a day, every time 15, on an empty stomach (take half an hour after to drink water in a large number, in order to avoid water down medicinal liquid).This medicine is taken the specific practice of better pan-fried tomato soup and is to decoct tomato soup and do extra conductant ingredient:Take from so well-done little tomato(50 grams or so)Chopping, puts 10 grams or so vegetable oil in pot, heat, be put into appropriate Flos Allii Fistulosi, Sal, pours into decoct in pot by the Fructus Lycopersici esculenti of chopping and fries 1-2 minutes, then infuse to get away into suitable quantity of water and take the dish out of the pot when Flos Allii Fistulosi blows out fragrance.Pungent grade to gastrointestinal irritation larger food is not eaten during medication.
The effect of each raw material of the present invention:
Radix Scutellariae,The root of lamiaceae labiatae scutellaria plant Radix Scutellariae.Nature and flavor are bitter, cold in nature.Effect:Taste clearing away damp-heat, pathogenic fire purging, removing toxic substances are antiabortive.It is clinicalUsing:Suitable for hepatocarcinoma, tumor of gallbladder.With otherChinese medicineCompatibilityTreatmentPulmonary carcinoma, colorectal cancer, sonCervical cancer, breast carcinoma, intestinal cancer, carcinoma of testis,Gastric cancerDeng.Additionally, also often treating warm disease heating, lung-heatCough, pneumonia, spitting of blood, jaundice, hepatitis, dysentery, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle etc..
Fructus Trichosanthis,Sweet, slight bitter, trembles with fear.Return lung, stomach, large intestine channel.Removing heat-phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, loosening bowel to relieve constipation.Fructus Trichosanthis master contains triterpene saponin.The fatty oil of seed, saponin.Pericarpium Trichosanthiss contain several amino acids and alkaloid etc..This product has eliminating the phlegm, coronary artery dilator, increases coronary flow, anti-hypoxia, effect for reducing blood fat.The treatment of coronary heart disease is clinically used for, has good therapeutic effect.There is inhibitory action to various pathogenic bacterias.Semen Trichosanthiss have catharsis effect.Experiment in vitro has antitumaous effect.Additionally, this product has inhibitory action to staphylococcus aureuses, Diplococcus pneumoniae, bacillus pyocyaneus, escherichia coli, Hemolytic streptococcuss and hemophilus influenza etc..
Herba Taraxaci, nature and flavor:Sweet, slight bitter is trembled with fear.Function:Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly:Upper respiratory tract infection, eye conjunctivitis, mumps, acute mastitis swell and ache, gastritis, dysentery, hepatitis, cholecystitis, acute appendicitiss, urinary system infection, pelvic inflammatory disease, ulcerative carbuncle, pharyngitis, controls acute mastitiss, lymphadenitises,, malignant boil carbuncle toxin, acute conjunctivitiss, cold, fever, acute tonsillitiss, acute bronchitiss, urinary tract infection.Its all herbal medicine, containing compositions such as taraxerol, taraxacin, caffeic acid, choline, inulin.There is significant galgctogogue action, treatment mastitis are largely effective.It is oral no matter juice is decocted, or smash to mud external application, all there is effect.Additionally, Herba Taraxaci also has diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting, aid digestion, increase appetite, treat gastric and duodenal ulcers, the effects such as can also prevent and treat gastric cancer, breast carcinoma and various tumor.
Nidus Vespae,Nature and flavor micro-sweet;It is mild-natured;Mild toxicity;Return through liver;Stomach;Kidney channel.Chemical analysis:The oil of the room containing dew, Cera Flava, resin, various saccharides, vitamin and inorganic salt etc..Indication:Wind-expelling pain-stopping;Rose poison detumescence;Killing parasites for relieving itching.Main wind carious pain;Carbuncle malignant boil;Scrofula;Mouthpiece swells and ache;Anal fistula;Rubella itch;Skin stubborn dermatitis etc..
Concha Ostreae,Flavor efficacy:Salty in the mouth, puckery, cold nature.Arresting sweating, controlling nocturnal emission with astringent drugs, softening the hard mass, antacid.Clinical practice:Suitable for kinds of tumors, such as hepatocarcinoma, gastric cancer, thyroid adenocarcinoma, pulmonary carcinoma, malignant lymphoma etc., additionally, apply also for spontaneous perspiration, night sweat, bleeding not during menses, hyperchlorhydria, dysphoria, palpitation and insomnia, is had a dizzy spell, twitches at lymphoid tuberculosiss, seminal emission.
Thallus Laminariae (Thallus Eckloniae),Nature and flavor are salty, tremble with fear.Returns spleen, liver and kidney channel.Effect:Vanishing sputum and dispelling knot, inducing diuresis to remove edema.Effect:1. this product contains phycocolloid acid, laminaran, laminine, several amino acids, polysaccharide, vitaminss, carotene, riboflavin, nicotinic acid, fatty acid, the inorganic salt such as 24-ethylidenecholest-5-en-3.beta.-ol. and iodine, calcium, potassium.Its iodine for containing and iodine compound have preventing and treating goiter due to iodine deficiency effect;Thallus Laminariae (Thallus Eckloniae) fluid extract powder has obvious reduce serum cholesterol effect;Sodium alginate has blood sugar lowering, strengthens humoral immunization and promotes lymphocyte transformations effect;Narrow leaf Thallus Laminariae (Thallus Eckloniae) extract and the Thallus Laminariae (Thallus Eckloniae) that comes into leaves have antitumor action;Thallus Laminariae (Thallus Eckloniae) potassium salt, laminine have hypotensive activity.Additionally, Thallus Laminariae (Thallus Eckloniae) root crude extract can relieving asthma, antitussive.This product still has slight defecating feces excretion.2. have research to think, Thallus Laminariae (Thallus Eckloniae) fish after should not repeatedly in a large number with clear water rinse, in case iodine and other component damages and affect the treatment.3. the product of compatibility blood circulation promoting and blood stasis dispelling, hard masses softening and resolving are also had, with controlling the disease persons such as goiter, thyroid tumor, tuberculous lymphadenitiss and liver cirrhosis.
Radix Angelicae Sinensis ,Property sweet, acrid, warm.Return liver, the heart, large intestine channel.Enrich blood, invigorate blood circulation, pain relieving, loosening bowel to relieve constipation.It is certified products when samphire root is classified as.Other Angelica acutilobas, Radix Levistici Officinalis, strand Radix Angelicae Sinensis, North Sea Radix Angelicae Sinensis etc. also make this product use in different regions.《Book on Chinese herbal medicine is stated》Cloud:" bitter in the mouth, temperature." enter the heart, liver, spleen channel.Composition:Containing volatile oil, fatty oil, retinoid material, Vitamin B12, Vitamin E, cupreol, ferulic acid etc..Using:Blood deficiency dizziness caused by tumor, headache, flaccidity syndrome and arthralgia syndrome, just it is puckery,StomachacheCan use Deng.
Bufo siccuss,Bufo siccuss taste raw meat, temperature, it is poisonous.Thoughts of returning home warp, with removing toxic substances, pain relieving, has one's ideas straightened outEffect.Can be used for treat Several Kinds of Malignancy, hepatitis, herpes zoster, hepatic ascites, nephropathy,Cyclomastopathy、HysteromyomaEtc. difficult miscellaneous diseases.Toad-cortex can for cancer, leukemia, lymphoma etc..Folks of china traditional Chinese medical science medical research development association compiles《CancerUnique secret recipe》Middle load:Cutis Bufonis nature and flavor raw meat, cool, micro- poison, function removing toxic substances, diuretic, relieving distension, cure mainly various tumor.Jing Shanghai Communications Universitys quantum medicines detection in 1999, especially to cancer, liver cirrhosis, all diseases of painTreatmentEffective content composition surpasses on 8,000 amount valencys(It is all have more than 8,000 amount valencys have immunologic function composition).Huaxia Press《The full allusion quotation of Traditional Chinese Medicine》Middle load:Toad-cortex poison is relatively light, is mainly used in sore swollen toxin and infantile malnutrition, modern conventional curing oncoma.Distant place publishing house《Chinese herbal medicine is complete works of》Middle introduction, toad-cortex can for cancer, leukemia, lymphoma etc..According to Popular Utilization investigate, toad-cortex have heat clearing away, removing toxic substances, reducing swelling and alleviating pain, calmness, diuresis, resistFluEffect of virus, and have effective to hepatic ascites, cancer, it is rightHepatitis BGreat three positive, small three positive can be turned out cloudy, moreover it is possible to quickly and effectively health invigorating and improve immunologic function, promote people's this metabolism balance of nature.Toad-cortex is the epidermis coating of Venenum Bufonis serosity, and Sun Simiao claims:" toad is sloughed off(Clothing)It is swollen except disliking, god ".Li Shizhen (1518-1593 A.D.)《Compendium of Materia Medica》Claim:One of " toad-cortex is which stores sufficient the essence of five ZANG-organs and six FU-organs gas, receives the China of world negative and positive precious, if obtain, all foul diseases do not have and do not heal ".The traditional Chinese medical science thinks the effect of toad-cortex has removing toxic substances and promoting subsidence of swelling, pain relieving, wards off foul, is widely used in the treatment of sore and toxic, laryngopharynx swelling and pain etc..Modern study is thought:The main alcoholic compound containing bufadienolide of toad-cortex, including bufalin and bufotoxin, with heart tonifying, boosting, antiinflammatory action, toad-cortex also has various magical functions such as antitumor, antiviral, can be used for treat Several Kinds of Malignancy, hepatitis, herpes zoster, hepatic ascites, nephropathy,Cyclomastopathy、HysteromyomaEtc. difficult miscellaneous diseases, bufalin also has stronger anesthetic action.
Rhizoma Belamcandae,Flavor efficacy:Bitter in the mouth, it is cold in nature.Heat-clearing and toxic substances removing, sore-throat relieving expectorant.Clinical practice:Suitable for laryngocarcinoma, pulmonary carcinoma etc..Additionally, apply also for having sore throat, productive cough asthma, parotitiss, bronchitis, amenorrhea, mastitis, external controls paddy-field dermatitis etc..
Rhizoma Polygonati Odorati,It is the dry rhizome of Liliaceae herbaceos perennial Rhizoma Polygonati Odorati.Sweet in the mouth cold nature, enters lung, and stomach, with nourishing YIN to relieve dryness, QI invigorating nourishing the stomach, the effect of promoting the production of body fluid to quench thirst, can control consumption of YIN caused by febrile disease, and diabetes, the few expectorant of dry cough, dry tongue are thirsty, dryness of the mouth and throat, pulmonary tuberculosis, the disease such as heart disease, and Rhizoma Polygonati Odorati effect relatively relaxes, ripe many with nourishing yin nourishing.Rhizoma Polygonati Odorati sweet in the mouth is mild-natured with many cough caused by dryness of gastric heat lung-heat, promoting the production of body fluid to quench thirst energy yin nourishing, thirsty the controlling of dry tongue are quenched one's thirst.
The Rhizoma Atractylodis Macrocephalae,Key medicine of the Rhizoma Atractylodis Macrocephalae for air making-up and spleen enlivening, for controlling syndrome of deficiency of spleen qi and stomach qi, diarrhea due to hypofunction of the spleen, dyspepsia, gastrointestinal tract disease, for controlling and middle spleen reinforcing, dehumidify QI invigorating, is assigned in tonic side, fills blood.The Rhizoma Atractylodis Macrocephalae both can air making-up and spleen enlivening, again can eliminate dampness and have diuretic effect, therefore be to control the good medicine of phlegm retention edema, for controlling various edema (such as renal, gestational, trophedema).Rhizoma Atractylodis Macrocephalae QI invigorating spleen reinforcing, has strengthening superficial resistance to stop perspiration to act on, for controlling exterior deficiency spontaneous perspiration, arthritis rheumatalgia.Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening, and have antiabortive effect, for controlling frequent fetal movement.The effect of the Rhizoma Atractylodis Macrocephalae mainly has calmness, vasodilation, anticoagulant, anti-gastric-ulcer, hepatic cholagogic, diuresis, strong, raising immunity, antioxidation, antibacterial and antitumor etc..Rhizoma Atractylodis Macrocephalae the spleen strengthening and damp drying is good, the multiplex life of eliminate dampness and have diuretic effect.Rhizoma Atractylodis Macrocephalae sweetness and bitterness temperature is nontoxic, and strengthening superficial resistance to stop perspiration disappears grain rice.Frequent fetal movement controls phlegm-damp, and diarrhea due to hypofunction of the spleen can all take.
Fructus Lycopersici esculenti,Fructus Lycopersici esculenti have weight-reducing, allaying tiredness, appetite stimulator, raising to the digestion of protein, reduce flatulence food stagnation the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, Fructus Lycopersici esculenti always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the Fructus Lycopersici esculenti in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction convert), anticancer propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have the cytokines secretion of anti-cancer, antitumaous effect, such as interleukin-II, dissolution of the activated lymphocyte to cancerous cell;The lymphocyte being activated can discharge cytokines such as tumor necrosis factor etc. again, have lethal effect to tumor cell.3rd, lycopene has stronger antioxidation.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene etc.) is effectively removing free radical, so as to play whole body health-care effect, wherein playing an important role in being just included in protective effect on cancer risk.
The effect of the present invention:
Cure mainly:Breast carcinoma, particularly front primary breast cancer, with very low cost, fundamentally improve physical function, and control tumor continues to overgrow and makes which that final disappearance is gradually reduced, so as to recover healthy.It is simultaneous to control:The cancers such as cancer of pancreas, hepatocarcinoma, pulmonary carcinoma, cervical cancer, human primary gastrointestinal cancers, skin carcinoma.
Our the characteristics of is:
1st, flavour of a drug, dosage are moderate, do not waste.
2nd, selected flavour of a drug are all to be proved for cancer particularly can to treat breast carcinoma by modern medicine pharmacological evaluation.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by modern medicine pharmacological evaluation proved function for cancer and effect.Really it is that the traditional Chinese medical science is seen a doctor by rule of thumb, folk prescription is cured the disease by risk!
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, be as a result that " dragon " is not harnessed the river more on the contrary.
4th, as much as possible " neutralization ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus made to be suffered within the cycle of whole medication less, be pulled the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " pathogenic fire reducing " are specifically solved for interim addition.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequencess.
Specific embodiment:Scorpio 6g, Galla Chinensiss 6g, Pseudobulbus Cremastrae Seu Pleioness 9g, Fructus Trichosanthis 20g, Radix Angelicae Sinensis 11g, Radix stephaniae tetrandrae 15, Herba Solani Lyrati 30g, Sargassum 30g, Thallus Laminariae (Thallus Eckloniae) 30g, Radix Rabdosiae glaucocalyciss 30g are respectively amplified into 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate are standby.Extract for second:The 5-7 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted or so half an hour, extraction fluid, pressure filtration, filtrate are standby.Third time is extracted:The 3-5 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted 20 minutes or so, extraction fluid, pressure filtration, filtrate are standby.Concentration:The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.Powder processed:Radix Angelicae Dahuricae 7g, Radix Salviae Miltiorrhizae 9g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.Dispensing:In 300,000 grades of dust proof workshops, above-mentioned medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.Drying, crushing:The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, is crossed 100 mesh sieves.Pelletize:The spice of mix homogeneously is inserted into pelletize in comminutor.Granulate:The granule for making is carried out into granulate, 35 mesh sieves are crossed.It is dried:Whole good granule is inserted in heat circulation drying oven, at 80 DEG C, aeration-drying is to moisture < 8%.Tabletting:Magnesium stearate mix homogeneously is added to be placed in tabletting in tablet machine medicine obtained by dry mixed(Also can coating), per piece 0.5.Packaging:First the tablet for pressing is loaded in vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).Finally, irradiated finished product is put in storage by the principle of first in first out.
Claims (2)
1. Hui ethnic group's Chinese medicine " Radix Scutellariae mammary gland drive cancer piece " and preparation method thereof, it is characterised in that it is by made by the raw material of following weight proportion:
Scorpio 6g, Galla Chinensiss 6g, Pseudobulbus Cremastrae Seu Pleioness 9g, Fructus Trichosanthis 20g,
Radix Angelicae Sinensis 11g, Radix Angelicae Dahuricae 7g, Radix stephaniae tetrandrae 15, Radix Salviae Miltiorrhizae 9g,
Herba Solani Lyrati 30g, Sargassum 30g,
Thallus Laminariae (Thallus Eckloniae) 30g, Radix Rabdosiae glaucocalyciss 30g
This side is the substantially square of one decoction on the one, in practical application, can also increase the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory according to the body constitution of patient and conditions“Dialectical compatibility " medicine.
2. the weight proportion of Hui ethnic group's Chinese medicine " Radix Scutellariae mammary gland drives cancer piece " according to claim 1 and preparation method thereof, it is characterised in that including following preparation processes:
A、
The preparation of extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Rhizoma Belamcandae 7g, Rhizoma Atractylodis Macrocephalae 9g, all amplify 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate are standby;
B, second extraction:The 5-7 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted or so half an hour, extraction fluid, pressure filtration, filtrate are standby;
C, third time are extracted:The 3-5 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted 20 minutes or so, extraction fluid, pressure filtration, filtrate are standby;
(2), concentration
The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby;
(3), powder processed
Rhizoma Belamcandae 7g, Rhizoma Atractylodis Macrocephalae 9g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir;
(5)、
Drying, crushing
The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, is crossed 100
Mesh sieve;
(6)、
Pelletize
The spice of mix homogeneously is inserted into pelletize in comminutor;
(7)、
Granulate
The granule for making is carried out into granulate, 35 mesh sieves are crossed;
(8)、
It is dried
Whole good granule is inserted in heat circulation drying oven, at 80 DEG C, aeration-drying is to moisture < 8%;
(9)、
Tabletting
Magnesium stearate mix homogeneously is added to be placed in tabletting in tablet machine medicine obtained by dry mixed(Also can coating), every 0.5g;
B、Packaging
First the tablet for pressing is loaded in vial or vinyon bottle, then the bottle mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy);
C、
Warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510749351.7A CN106668524A (en) | 2015-11-08 | 2015-11-08 | Hui nationality traditional Chinese medicine radix scutellariae tablet for treating breast cancer and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510749351.7A CN106668524A (en) | 2015-11-08 | 2015-11-08 | Hui nationality traditional Chinese medicine radix scutellariae tablet for treating breast cancer and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
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CN106668524A true CN106668524A (en) | 2017-05-17 |
Family
ID=58858393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201510749351.7A Withdrawn CN106668524A (en) | 2015-11-08 | 2015-11-08 | Hui nationality traditional Chinese medicine radix scutellariae tablet for treating breast cancer and preparation method thereof |
Country Status (1)
Country | Link |
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CN (1) | CN106668524A (en) |
-
2015
- 2015-11-08 CN CN201510749351.7A patent/CN106668524A/en not_active Withdrawn
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