CN106667440A - Chargeable system for detecting pathological change of tissue - Google Patents

Chargeable system for detecting pathological change of tissue Download PDF

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Publication number
CN106667440A
CN106667440A CN201611268447.2A CN201611268447A CN106667440A CN 106667440 A CN106667440 A CN 106667440A CN 201611268447 A CN201611268447 A CN 201611268447A CN 106667440 A CN106667440 A CN 106667440A
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China
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module
communication module
lesion
implantable medical
communication
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CN201611268447.2A
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CN106667440B (en
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不公告发明人
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Beijing Pins Medical Co Ltd
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Beijing Pins Medical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1072Measuring physical dimensions, e.g. size of the entire body or parts thereof measuring distances on the body, e.g. measuring length, height or thickness
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4848Monitoring or testing the effects of treatment, e.g. of medication
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/74Details of notification to user or communication with user or patient ; user input means
    • A61B5/746Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0858Detecting organic movements or changes, e.g. tumours, cysts, swellings involving measuring tissue layers, e.g. skin, interfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372Arrangements in connection with the implantation of stimulators
    • A61N1/378Electrical supply
    • A61N1/3787Electrical supply from an external energy source

Abstract

The invention discloses a chargeable system for detecting the pathological change of tissue. The chargeable system comprises an implantable medical device and an in-vitro detector. The implantable medical device is implanted in a patient body and comprises a sensor module, a first processor module, a charging coil, at least one main battery, at least one standby battery, an awakening module and a first communication module. The in-vitro detector is arranged in an in-vitro mode and comprises an ultrasonic wave generating module, an ultrasonic wave receiving module, a second processor module, an early warning module and a second communication module for wireless communication. The first processor module controls the charging coil and the standby battery to charge the main battery. Electric energy of the chargeable system for detecting the pathological change of the tissue is rapidly supplemented through the charging system.

Description

A kind of lesion tissue detecting system of charging
Technical field
The present invention relates to a kind of medical implant system, in particular to a kind of lesion tissue detecting system of charging.
Background technology
Various implantable medical devices(IMDS)It is including the pacemaker for clinical implanted device, defibrillator, its His electrical stimulation device includes spinal cord, brain deep, nerve, muscular irritation, drug delivery system, heart and other physiological monitors, Artificial cochlea etc..Although the surgery of implanted device is the material compatible with tissue, such as titanium, but is gone back after human body is implanted into It is to have due to friction or the risk for causing surrounding tissue ulceration, infecting that rejects.Implantable medical device implantation human body after by Cause surrounding tissue inflammation, ulceration in factors such as friction, rejection, infection;Typically now use B ultrasonic or ultrasonic development technology Lesion is analyzed, the method needs patient to be checked to hospital.But, regarded the trouble of implantable medical device operation Person has found that wound is abnormal and when arriving examination in hospital, has had already passed by best occasion for the treatment.
Chinese patent CN104958075A discloses a kind of using Raman spectrum non-invasive measurement skin thickness and blood sugar Concentration and its calibration method, wherein measuring the noninvasive method of person under inspection's skin thickness and blood sugar concentration by Raman system. Advantage is, it uses single Raman spectrum to measure skin thickness and blood sugar concentration, and the skin as obtained by same Raman spectrum Skin thickness data and raman scattering intensity data are combined to obtain more accurate blood sugar concentration.
It can be seen that, implantable medical device surrounding skin thickness is detected at any time after implantable medical device implantation human body, and Ulceration situation to tissue around carries out early warning;In addition, carrying out timely quick charge to the implantable medical device.
The content of the invention
It is an object of the invention in overcoming the shortcomings of above-mentioned technology, there is provided a kind of lesion tissue detecting system of charging, Including, implantable medical device and vitro detection device;Implantable medical device implantation within a patient, including sensor, at first Reason device module, at least charge coil, at least a main battery, a reserve battery, wake module and first communication module;First treatment Device module control charge coil charges to an at least main battery and an at least reserve battery;First processor module control at least one Reserve battery charges to an at least main battery.
Vitro detection device, is set in vitro, including ultrasonic wave occurs module, ultrasonic wave receiver module, second processing device mould Block, second communication module, warning module, implantable medical device can be with the of skin detectors by its first communication module Two communication modules carry out radio communication;Sensor may include that body temperature trans, germ sensor, starch enzyme sensor, antibody are passed Sensor;The second processing device module of vitro detection device periodically controls ultrasonic wave transmitter module and ultrasonic wave receiver module detection wound Neighbouring skin thickness, when skin thickness intensity of variation is more than the first lesion threshold value, then may group around implantable medical device The sick change of hair-weaving, is communicated by second communication module with the first communication module of implantable medical device, and sending may lesion letter Breath;Postprocessor module control wake module wake up sensor further detect, carry out body temperature, germ, amylase or antibody Detection, body temperature trans can be located at patient oxter, and germ sensor can be located at the border circular areas that wound radius is 3-5cm It is interior, if testing result reaches the second lesion threshold value, it is determined that implanted device tissue around lesion, by first communication module with Pathological Information is sent to vitro detection device by second communication module, and second processing device module control warning module carries out early warning.
Further, the system may also include remote server and doctor's main frame, and vitro detection device may also include threeway Letter module, the third communication module of vitro detection device can be by being wirelessly or non-wirelessly connected to remote server, and warning module is pre- Pathological Information is also sent to by remote server by third communication module after police, is available for doctor to be accessed in doctor's main frame.
Further, the sensor of implantable medical device can periodically be waken up detection implantable medical device tissue around Physiological parameter and vitro detection device is sent to by first communication module and second communication module, and by third communication module Remote server is uploaded to, doctor can check patient data by doctor's main frame.
Further, main battery and reserve battery are Li-Ion rechargeable battery or other rechargeable batteries, or are filled soon Battery.
Brief description of the drawings
Fig. 1 is the lesion tissue detecting system figure of charging of the invention.
The doctor's main frame of 101. implantable medical device, 102. monitored in vitro device, 103. remote server 104..
The first communication module of 201. sensor, 202. first processor module, 203. wake module 204..
301. ultrasonic vocalization module, 302. ultrasonic wave receiver module, 303. second processing device module 304. second communicates The third communication module of 305. warning module of module 306..
Specific embodiment
The present invention is further described with reference to the accompanying drawings and examples.
Accompanying drawing 1 shows the lesion tissue detecting system schematic diagram of the charging that treatment is provided to patient.The system includes planting Enter medical treatment device 101 and monitored in vitro device 102, implantable medical device can be that any suitable offer to patient is treated Implanted device, it generates and delivers electro photoluminescence to body nerve and organize the treatment for various biological disorders, e.g. The device of heart rate management treatment is provided to heart, it is possible to including for example implantable pacemaker, heart multiple rate device and/or defibrillation Device, these devices can provide treatment via lead etc. to patient's heart;Cochlear stimulation device, the treatment blindness of deafness are for example treated again Retina stimulator, the ailing spinal stimulator of the limb motion muscle stimulator that produces collaboration, treatment etc..Implantable medical Device can also be the electrocardiosignal and/or other physiological parameters for sensing patient's heart(For example, blood oxygen saturation, blood pressure, Heart rate, body temperature, respiratory rate etc.), and above-mentioned signal and/or physiological parameter are stored to be recorded, analyzed for clinician. Monitored in vitro device 102 is used to monitor whether implantable device tissue around occurs lesion and send prompting.
1 illustrate the structure of the lesion tissue monitoring system referring to the drawings.Implantable medical device is implanted into patient In vivo, it include sensor 201, first processor module 202, charge coil, an at least main battery, an at least reserve battery, Wake module 203 and first communication module 204.Wherein, sensor 201 is connected with first processor module 202, for that will gather One or more physiological parameter be sent to first processor module 202, above-mentioned one or more physiological parameter can be can The various parameters of patient body situation and/sign lesion tissue are characterized, such as body temperature, blood pressure, blood oxygen, germ etc. can sense The sensor of these parameters includes body temperature trans, starch enzyme sensor, blood pressure sensor, antibody sensor, germ sensor Patient oxter is can be located at Deng, body temperature trans, germ sensor can be located in the border circular areas that wound radius is 3-5cm. Sensor 201 could be arranged to the one kind in the sensor, it is also possible to be set to by multiple sensor groups into sensor array Row.First processor module 202 is connected with sensor 201, one or more for obtaining and locating the collection of reason sensor 201 Physiological signal, and treatment judgement is carried out, first processor module 202 is also connected with first communication module 204, wake module 203, Operation for controlling above-mentioned two module.Wake module 203 is connected with first processor module 202 and sensor 201 respectively, uses Waking up sensor in the control for receiving first processor module 202 carries out secondary detection.The treatment of first communication module 204 and first Device module 202 is connected, for being communicated with second communication module 304, to realize implantable medical device 101 and monitored in vitro device 102 communication.The control charge coil of first processor module 202 charges to an at least main battery and an at least reserve battery;The One processor module 202 also controls an at least reserve battery to be charged to an at least main battery.
Monitored in vitro device 102, is set in vitro, carries out data exchange to monitor patient's shape with implantable medical device 101 Condition, it includes that ultrasonic wave occurs module 301, ultrasonic wave receiver module 302, second processing device module 303, second communication module 304 and warning module 305.Wherein, ultrasonic wave transmitter module 301, ultrasonic wave receiver module 302 receive second processing device module Order, periodically changed with detecting skin thickness near wound using ultrasonic wave.Above-mentioned ultrasonic wave occurs module 301 to be included surpassing Sonic probe, the probe can be common shape, such as disc, and probe quantity can be one or more.Second processing device mould There is module 301, ultrasonic wave receiver module 302, second communication module 304 and warning module 305 with ultrasonic wave respectively in block 303 It is connected, controls the operation of above-mentioned module, the first lesion threshold value for pre-setting and the while second processing device module 303 is stored with Two lesion threshold values, for judging whether implantable medical device surrounding tissue occurs lesion.Second communication module 304 is used for and the One communication module 204 communicates, to send possible Pathological Information.Warning module 305 is used to carry out early warning, early warning to possible lesion The mode haptic signal such as the voice signal such as visual signal, buzzing and/or vibrations such as including LED.
The working method of the detailed description below implantable medical device lesion tissue monitoring system.System has is used for day First working condition and the second working condition for determining lesion of often monitoring.Implantable medical device 101 is normally being used During, system starts i.e. into the first working condition, and under the state, sensor 201 is configured in patient body and respectively gathers position Put, collection patient items physiological parameter is simultaneously recorded to carry out monitor in real time, and ultrasonic wave transmitter module 301 is arranged in patient's wound Mouthful nearby skin, receives the trigger signal of second processing device module 303, periodically to launching ultrasonic wave, ultrasonic wave arteries and veins in patient's body It was punched through human body skin, fat and reached muscle, muscle reflection echo signal received the echo by ultrasonic wave receiver module 302, passed through The pretreatment to signal is crossed, then sends result to second processing device module 303, calculating arrangement is carried out to data, to obtain skin Skin thickness, and the skin thickness that obtains will be measured compared with the skin thickness of the last measurement of storage, when skin thickness change Change during more than default first lesion threshold value, then implantable medical device surrounding tissue may occur lesion.Once judgement is possible to Generation lesion, system is to start the second working condition.Now, second processing device module 303 i.e. start second communication module 304 with First communication module 204 is communicated, and the control wake module 203 of first processor module 202 wakes up sensor 201 to be carried out targetedly Secondary detection, body temperature is carried out according to the species that lesion may occur, germ, the detection of amylase or antibody will inspection after detection Survey data to send again to second processing device module 303, and compared with default second lesion threshold value, if the secondary detection Result reaches the second lesion threshold value, it is determined that implantable medical device tissue around occurs lesion, and warning module 305 is started immediately Early warning is carried out, informs that patient and/or care provider have occurred and that lesion, it is necessary to treatment in time.
Further, the system also includes remote server 103 and doctor's main frame 104, and monitored in vitro device may also include the Three communication modules 306, the third communication module 306 can be by being wirelessly or non-wirelessly connected to remote server 103.When it is determined that hair After sick change, i.e., after system enters the second working condition, in addition to control warning module 305 carries out early warning, also by the third communication Pathological Information is sent to remote server 103 by module 306, is available for doctor to be accessed in doctor's main frame, is easy to doctor to patient's Quick disposal.
Further, for the patient of long periods of wear, the sensor 201 of implantable medical device 101 can also quilt It is set to periodically be waken up the physiological parameter of detection implantable medical device tissue around and passes through first communication module 204 and the Two communication modules 304 are sent to monitored in vitro device 102, and are uploaded to remote server 103 by third communication module 306, doctor Life can check patient data by doctor's main frame 104.
Embodiment:The system also includes remote server 103 and doctor's main frame 104, and vitro detection device may also include the 3rd Communication module, the third communication module of vitro detection device can be by being wirelessly or non-wirelessly connected to remote server, warning module Pathological Information is also sent to by remote server by third communication module after early warning, is available for doctor to be accessed in doctor's main frame.
The sensor of implantable medical device can periodically be waken up the physiology ginseng of detection implantable medical device tissue around Number is simultaneously sent to vitro detection device, and be uploaded to far by third communication module by first communication module and second communication module Journey server, doctor can check patient data by doctor's main frame.

Claims (7)

1. the lesion tissue detecting system of a kind of charging, it is characterised in that:Including implantable medical device(101)And vitro detection Device(102);The implantable medical device(101)Implantation within a patient, including sensor assembly(201), first processor mould Block(202), charge coil, at least a main battery, at least a reserve battery, wake module(203)And first communication module (204);The first processor module(202)The charge coil is controlled to an at least main battery and described at least standby Charged with battery;The first processor module(202)An at least reserve battery described in control fills to an at least main battery Electricity;The vitro detection device(102), set in vitro, including there is module in ultrasonic wave(301), ultrasonic wave receiver module (302), second processing device module(303), warning module(305), second communication module block(304)Carry out radio communication.
2. the lesion tissue detecting system for charging according to claim 1, it is characterised in that:The sensor assembly(201) May include body temperature trans, germ sensor, starch enzyme sensor and antibody sensor.
3. the lesion tissue detecting system for charging according to claim 1, it is characterised in that:The vitro detection device(102) The second processing device module(303)Periodically control the ultrasonic wave transmitter module(301)With the ultrasonic wave receiver module (302)Skin thickness near detection wound, when skin thickness intensity of variation is more than the first lesion threshold value, then possibility is described can Implantable medical device(101)There is lesion in surrounding tissue, by the second communication module(304)Set with the implantable medical It is standby(101)The first communication module(204)Communication, sending may Pathological Information.
4. the lesion tissue detecting system for charging according to claim 1, it is characterised in that:The processor module controls institute State wake module(203)Wake up the sensor assembly(201)Further detection, carries out body temperature, germ, amylase and antibody Detection, the body temperature trans can be located at patient oxter, and the germ sensor can be located at the circle that wound radius is 3-5cm In shape region, if testing result reaches the second lesion threshold value, it is determined that the possible implantable medical device(101)Tissue around Lesion, by the first communication module(204)With the second communication module(304)Pathological Information is sent to described external Detector(102), the second processing device module(303)Control the warning module(305)Carry out early warning.
5. the lesion tissue detecting system for charging according to claim 1, it is characterised in that:The detecting system may also include far Journey server(103)With doctor's main frame(104), the vitro detection device(102)May also include third communication module(306), institute State vitro detection device(102)The third communication module(306)Can be by being wirelessly or non-wirelessly connected to the remote service Device(103), the warning module(305)Also by the third communication module after early warning(305)Pathological Information is sent to institute State remote server(103), doctor is available in doctor's main frame(104)Access.
6. the lesion tissue detecting system for charging according to claim 5, it is characterised in that:The sensor assembly(201) The detection implantable medical device can be periodically waken up(101)The physiological parameter of tissue around simultaneously passes through the described first communication mould Block(204)With the second communication module(304)It is sent to the vitro detection device(102), and by the third communication mould Block(306)It is uploaded to the remote server(103), doctor can be by doctor's main frame(104)Check patient data.
7. the lesion tissue detecting system for charging according to claim 1, it is characterised in that:The main battery and described standby Battery is Li-Ion rechargeable battery.
CN201611268447.2A 2016-12-31 2016-12-31 Charged tissue lesion detection system Active CN106667440B (en)

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Application Number Priority Date Filing Date Title
CN201611268447.2A CN106667440B (en) 2016-12-31 2016-12-31 Charged tissue lesion detection system

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Application Number Priority Date Filing Date Title
CN201611268447.2A CN106667440B (en) 2016-12-31 2016-12-31 Charged tissue lesion detection system

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CN106667440B CN106667440B (en) 2023-05-30

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3813710A4 (en) * 2018-06-26 2022-03-16 Australian Institute of Robotic Orthopaedics Pty Ltd Implant fit analysis

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000229078A (en) * 1999-02-10 2000-08-22 Japan Science & Technology Corp Vascular lesion diagnositic system and diagnostic program memory storage medium
US20080262374A1 (en) * 2007-04-19 2008-10-23 Medtronic, Inc. Event triggered infection monitoring
US20090024054A1 (en) * 2007-07-20 2009-01-22 Arnaud Lazarus Implantable medical device
US20100305430A1 (en) * 2007-09-26 2010-12-02 Volker Troesken Tissue marker
CN202957629U (en) * 2012-11-16 2013-05-29 移康智能科技(上海)有限公司 Double-battery powered electronic door viewer

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000229078A (en) * 1999-02-10 2000-08-22 Japan Science & Technology Corp Vascular lesion diagnositic system and diagnostic program memory storage medium
US20080262374A1 (en) * 2007-04-19 2008-10-23 Medtronic, Inc. Event triggered infection monitoring
US20090024054A1 (en) * 2007-07-20 2009-01-22 Arnaud Lazarus Implantable medical device
US20100305430A1 (en) * 2007-09-26 2010-12-02 Volker Troesken Tissue marker
CN202957629U (en) * 2012-11-16 2013-05-29 移康智能科技(上海)有限公司 Double-battery powered electronic door viewer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3813710A4 (en) * 2018-06-26 2022-03-16 Australian Institute of Robotic Orthopaedics Pty Ltd Implant fit analysis

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