CN106633288A - 一种药用包装材料 - Google Patents

一种药用包装材料 Download PDF

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CN106633288A
CN106633288A CN201611078816.1A CN201611078816A CN106633288A CN 106633288 A CN106633288 A CN 106633288A CN 201611078816 A CN201611078816 A CN 201611078816A CN 106633288 A CN106633288 A CN 106633288A
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parts
package material
packaging material
ethylene
polyvinylpyrrolidone
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张顺伟
唐进六
陈伟
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XUHUA PHARMACEUTICAL CO Ltd SICHUAN
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XUHUA PHARMACEUTICAL CO Ltd SICHUAN
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04—Homopolymers or copolymers of ethene
    • C08L23/06—Polyethene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B32B15/085—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyolefins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/20—Layered products comprising a layer of metal comprising aluminium or copper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
    • B32B27/327—Layered products comprising a layer of synthetic resin comprising polyolefins comprising polyolefins obtained by a metallocene or single-site catalyst
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D65/00—Wrappers or flexible covers; Packaging materials of special type or form
    • B65D65/38—Packaging materials of special type or form
    • B65D65/40—Applications of laminates for particular packaging purposes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
    • C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L27/04—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
    • C08L27/08—Homopolymers or copolymers of vinylidene chloride
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/73—Hydrophobic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/08—Stabilised against heat, light or radiation or oxydation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/14—Gas barrier composition
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/02—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend
    • C08L2205/035—Polymer mixtures characterised by other features containing three or more polymers in a blend containing four or more polymers in a blend

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Packages (AREA)
  • Laminated Bodies (AREA)

Abstract

本发明公开了一种药用包装材料，所述包装材料包括铝箔层、粘结层、热封层，其中热封层由茂金属聚乙烯与预混物共挤出制得：所述预混物包括医药或食品级聚偏二氯乙烯(PVDC)、乙烯‑丙烯共聚物、羧甲基纤维素、聚乙烯吡咯烷酮和二丁基羟基甲苯、石膏。本发明制得的包装材料可用于片剂、药丸、胶囊等剂型的包装，阻湿、阻气、防氧化性能优异，药品可长期在湿热环境下存放，同时包装的加工性能好，成型难度低。

Description

一种药用包装材料
技术领域
本发明涉及药用包装材料的技术领域，特别涉及铝塑包装材料的技术领域。
背景技术
铝塑泡罩包装大量应用于药品片剂、胶囊的包装中，现有技术中这类包装材料通常存在阻隔性能欠佳，特别是阻湿、阻气性能不太理想，导致药品在存放时出现变质的现象。
发明内容
本发明的目的在于提出一种具有高效的阻湿、阻气、防氧化性能的药用包装材料。
本发明的技术方案如下：
一种药用包装材料，包括铝箔层、粘结层、热封层，其中热封层由茂金属聚乙烯与预混物共挤出制得：所述预混物包括医药或食品级聚偏二氯乙烯(PVDC)、乙烯-丙烯共聚物、羧甲基纤维素、聚乙烯吡咯烷酮和二丁基羟基甲苯、石膏。
优选的是：所述预混物按质量份计，包括聚偏二氯乙烯15～20份，乙烯-丙烯共聚物3～5份，羧甲基纤维素1～1.5份，聚乙烯吡咯烷酮0.8～1.2份，二丁基羟基甲苯0.1～0.3份，石膏0.5～1份。
另外优选的是：所述预混物按质量份计，所述预混物按质量份计，包括聚偏二氯乙烯15份，乙烯-丙烯共聚物3份，羧甲基纤维素1.2份，聚乙烯吡咯烷酮1.0份，二丁基羟基甲苯0.2份，石膏0.8份。
本发明制得的包装材料可用于片剂、药丸、胶囊等剂型的包装，阻湿、阻气、防氧化性能优异，药品可长期在湿热环境下存放，同时包装的加工性能好，成型难度低。
具体实施方式
实施例1
一种药用包装材料，包括铝箔层、粘结层、热封层，其中热封层由茂金属聚乙烯与预混物共挤出制得：所述预混物包括聚偏二氯乙烯15份，乙烯-丙烯共聚物3份，羧甲基纤维素1份，聚乙烯吡咯烷酮0.8份，二丁基羟基甲苯0.1份，石膏0.5份。
实施例2
一种药用包装材料，包括铝箔层、粘结层、热封层，其中热封层由茂金属聚乙烯与预混物共挤出制得：包括聚偏二氯乙烯20份，乙烯-丙烯共聚物5份，羧甲基纤维素1.5份，聚乙烯吡咯烷酮1.2份，二丁基羟基甲苯0.3份，石膏1份。
实施例3
一种药用包装材料，包括铝箔层、粘结层、热封层，其中热封层由茂金属聚乙烯与预混物共挤出制得：所述预混物包括聚偏二氯乙烯15份，乙烯-丙烯共聚物3份，羧甲基纤维素1.2份，聚乙烯吡咯烷酮1.0份，二丁基羟基甲苯0.2份，石膏0.8份。

Claims (3)

1.一种药用包装材料，其特征在于：所述包装材料包括铝箔层、粘结层、热封层，其中热封层由茂金属聚乙烯与预混物共挤出制得：所述预混物包括医药或食品级聚偏二氯乙烯(PVDC)、乙烯-丙烯共聚物、羧甲基纤维素、聚乙烯吡咯烷酮和二丁基羟基甲苯、石膏。
2.根据权利要求1所述的药用包装材料，其特征在于：所述预混物按质量份计，包括聚偏二氯乙烯15～20份，乙烯-丙烯共聚物3～5份，羧甲基纤维素1～1.5份，聚乙烯吡咯烷酮0.8～1.2份，二丁基羟基甲苯0.1～0.3份，石膏0.5～1份。
3.根据权利要求1所述的药用包装材料，其特征在于：所述预混物按质量份计，包括聚偏二氯乙烯15份，乙烯-丙烯共聚物3份，羧甲基纤维素1.2份，聚乙烯吡咯烷酮1.0份，二丁基羟基甲苯0.2份，石膏0.8份。
CN201611078816.1A 2016-11-30 2016-11-30 一种药用包装材料 Pending CN106633288A (zh)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107312275A (zh) * 2017-06-30 2017-11-03 南宁东印时代广告有限公司 药品用包装材料
CN108034219A (zh) * 2017-12-29 2018-05-15 叶芳 一种抗菌包装材料的制备方法及其应用

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CN2620628Y (zh) * 2003-05-30 2004-06-16 罗建华 聚氯乙烯、改性聚丙烯、聚偏二氯乙烯复合硬片
CN2714314Y (zh) * 2004-03-23 2005-08-03 段成钢 高阻隔包装材料
CN102001486A (zh) * 2009-08-28 2011-04-06 翁文桂 一种阻隔性叠层聚合物薄膜包装材料
CN102202986A (zh) * 2008-11-06 2011-09-28 克勒克纳彭塔普拉斯特有限及两合公司 多层膜片
CN103009747A (zh) * 2012-12-24 2013-04-03 苏州海顺包装材料有限公司 一种除湿防潮封装薄膜及其制备方法
CN104385565A (zh) * 2014-09-03 2015-03-04 福建师范大学 一种三层共挤复合高阻隔性吹塑薄膜的制备方法

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CN2714314Y (zh) * 2004-03-23 2005-08-03 段成钢 高阻隔包装材料
CN102202986A (zh) * 2008-11-06 2011-09-28 克勒克纳彭塔普拉斯特有限及两合公司 多层膜片
CN102001486A (zh) * 2009-08-28 2011-04-06 翁文桂 一种阻隔性叠层聚合物薄膜包装材料
CN103009747A (zh) * 2012-12-24 2013-04-03 苏州海顺包装材料有限公司 一种除湿防潮封装薄膜及其制备方法
CN104385565A (zh) * 2014-09-03 2015-03-04 福建师范大学 一种三层共挤复合高阻隔性吹塑薄膜的制备方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107312275A (zh) * 2017-06-30 2017-11-03 南宁东印时代广告有限公司 药品用包装材料
CN108034219A (zh) * 2017-12-29 2018-05-15 叶芳 一种抗菌包装材料的制备方法及其应用

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