CN106623205A - Quick plate washing machine for microporous reaction plate and plate washing method - Google Patents
Quick plate washing machine for microporous reaction plate and plate washing method Download PDFInfo
- Publication number
- CN106623205A CN106623205A CN201710084491.6A CN201710084491A CN106623205A CN 106623205 A CN106623205 A CN 106623205A CN 201710084491 A CN201710084491 A CN 201710084491A CN 106623205 A CN106623205 A CN 106623205A
- Authority
- CN
- China
- Prior art keywords
- plate
- cleaning
- washing machine
- box body
- elisa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000005406 washing Methods 0.000 title claims abstract description 31
- 238000000034 method Methods 0.000 title claims abstract description 14
- 238000004140 cleaning Methods 0.000 claims abstract description 67
- 239000007788 liquid Substances 0.000 claims abstract description 10
- 238000002965 ELISA Methods 0.000 claims description 33
- 239000012530 fluid Substances 0.000 claims description 8
- 238000010926 purge Methods 0.000 claims description 6
- 238000012360 testing method Methods 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 4
- 230000001737 promoting effect Effects 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000011148 porous material Substances 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 4
- 230000002000 scavenging effect Effects 0.000 description 3
- 206010011409 Cross infection Diseases 0.000 description 2
- 206010029803 Nosocomial infection Diseases 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000003434 inspiratory effect Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/02—Cleaning by the force of jets or sprays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/12—Drying solid materials or objects by processes not involving the application of heat by suction
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B9/00—Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards
- F26B9/06—Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards in stationary drums or chambers
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Cleaning By Liquid Or Steam (AREA)
Abstract
The invention relates to a quick plate washing machine for a microporous reaction plate and a plate washing method. The invention aims to solve the problem that in the prior art, the cleaning equipment is great in volume, long in cleaning time and low in biological safety grade. The quick plate washing machine provided by the invention comprises a box body and a cover body which are hermetically connected, an elisa plate placing chamber is arranged in the cover body, through holes corresponding to plate pores of the elisa plate in quantity and size are formed, and an elisa plate cleaning system and an elisa plate swabbing-off system are arranged in the cover body; the elisa plate cleaning system comprises a cleaning plate, cleaning needles corresponding to the plate pores of the elisa plate in quantity and size are arranged on the upper surface of the cleaning plate, and the cleaning needles are hollow inside and are externally connected to a liquid source of a cleaning liquid after communicating a cavity in the bottom of the cleaning plate; the elisa plate swabbing-off system comprises an air outlet pipe arranged on the plate washing machine and a negative pressure source connected to the air outlet pipe. The quick plate washing machine provided by the invention has the beneficial effects that the quick plate washing machine is small in size which is 1/3 of that of the elisa quick plate washing machine in the prior art, short in cleaning time, low in noise and high in cleaning degree.
Description
Technical field
The present invention relates to inspection cleaning equipment, the quick board-washing machine of particularly a kind of micro reaction plate and plate washing method.
Background technology
ELISA Plate, also known as micro reaction plate.Enzyme linked immunological chemical experiment is widely used to multi-door such as medical science, biology
In the research and detection work of section.Need to change different reaction substrates in the immunoreaction process, therefore as reaction vessel
The cleaning of ELISA Plate just becomes reaction must Jing steps.
In enzyme linked immunological experiment and detection process, often using ELISA Plate as reaction vessel and zymophore.During experiment
Often add in each micropore by reaction reagent and by experiment sample, reacted in the environment of simulation human body temperature.Question response
Reactant in the ELISA Plate micropore not reacted is washed away after end, is stayed and is reacted and combine the thing on micro-pore wall
Matter, this process is referred to as board-washing.Just other reaction substrates can be added after board-washing, the experimentation of next step is carried out.Present each reality
The board-washing process for testing room is typically completed in two steps, and the first step is to inject washing lotion repeatedly in micropore to be cleaned；Second step is clear
Except the residual washing lotion in micropore；This step often needs experiment technical personnel manpower to have the final say, minimum to ensure micropore residual washing lotion.
Also have by the way of mechanical cleaning, such as in disclosed patent document, notification number is CN2021185418U, name
For the patented technology of Elisa plate horizontal type backflushing automatic wash-blow cleaning machine, disclosing one kind can be automatically performed board-washing and automatic spin-drying
ELISA Plate cleaning equipment；In prior art, the technology of also a kind of featheriness for further completing to remain moisture content by air-blowing.
However, technical staff has found, still have the disadvantage that in prior art：1. due to needing centrifugal drier
Dry, reorganize and outfit overall volume greatly, be not easy to transition and carry；2. the moisture entrapment after cleaning tends not to rapid all discharges,
Scavenging period is long；3. air-blowing featheriness meeting large batch of introducing extraneous air in system, reduces its sanitary grade.
The content of the invention
The purpose of the present invention is exactly big in order to solve the cleaning equipment volume of prior art ELISA Plate, and scavenging period is long, raw
The low problem of thing safe class.
To solve above-mentioned technical problem, the concrete scheme of the present invention is：
A kind of quick board-washing machine of micro reaction plate is designed, including the box body and lid that are tightly connected, ELISA Plate is provided with lid and is put
The plate hole for putting chamber and correspondence ELISA Plate is provided with the corresponding through hole of number size, and ELISA Plate purging system is provided with the box body
System is drained with ELISA Plate；The ELISA Plate purging system includes cleaning sprayer corresponding with each through hole and is connected with cleaning sprayer
The liquid source of the cleaning fluid for connecing, specifically, including clean plate, the clean plate upper surface is provided with the plate hole number size with ELISA Plate
Corresponding cleaning needle, the cleaning needle inner hollow connect with clean plate bottom cavity after external cleaning fluid liquid source；The enzyme
Target drain system include being arranged on board-washing machine, the escaping pipe of connection tray interior and the negative pressure that is connected with the escaping pipe
Source, the lid is provided with pressure relief means thereon.
Preferably, the pipeline for forming negative pressure source is escaping pipe, the middle and lower part of the box body side is arranged at, in the lid
Bottom is additionally provided with outlet pipe, and the outlet pipe is in parallel with the escaping pipe, and on the outlet pipe valve is provided with.
Preferably, cleaning sprayer is installed on clean plate, is moving sets connection between the clean plate and the box body, in institute
State clean plate and be provided with slide block, the corresponding relative position in box body is provided with chute, and the edge of clean plate is apart between box body
Spacing is more than 2mm.
The upper surface of the clean plate is provided with the inclined-plane for promoting current to fall.
Preferably, the inclined-plane is ball crown surface.
Or, the inclined-plane is up-small and down-big prism-frustum-shaped surface.
Preferably, the box body and the hinged connection of lid.
Or, the box body and lid spiral-lock are in one.
Preferably, the contact surface of the box body and lid is provided with sealing strip.
The invention further relates to a kind of cleaning method using the board-washing machine, comprises the following steps that：
（1）Dispose and position：ELISA Plate is installed on into the specified location in cleaning chamber, thereon each test hole lower section correspondence sets
There is the delivery port of cleaning device；
（2）Cleaning：The liquid source of external cleaning fluid, it is a length of when being carried out with hole by each test of the cleaning device to ELISA Plate
The cleaning of 5～15s, the current direction Jing lower sections outlet pipe after cleaning flows out；
（3）Cleaning：Outlet pipe is closed, cleaning chamber constitutes annular seal space, a length of 5～55s when connection negative pressure source in annular seal space to carrying out
Air-breathing, remove moisture remaining in annular seal space.
The beneficial effects of the present invention is：
（1）Small volume, is the 1/3 of prior art ELISA Plate cleaning machine, is easy to carry and transition, low cost；
（2）It is oriented to using current gravity and negative pressure absorbing, in combination with the switch of pipeline, scavenging period is short, noise is low, further
Avoid later stage cross-infection；
（3）Negative pressure absorbing avoids the disadvantage that prior art wind is dry or dries, and has not both needed supporting drier, it is not required that
It is introduced back into the uncertainty that extraneous air causes experimental result；
（4）The drippage of current after cleaning is easy on the chassis of syringe needle, and further reduction syringe needle panel surface is dripped to remain and gives later stage cleaning
The difficulty of increase.
Description of the drawings
Fig. 1 is that axle of the present invention surveys direction structure schematic diagram；
Fig. 2 is the main view direction structure schematic diagram of Fig. 1 structures；
Fig. 3 is the left view direction structure schematic diagram of Fig. 1 structures；
Fig. 4 is the right apparent direction structural representation of Fig. 1 structures；
Fig. 5 is the overlook direction structural representation of Fig. 1 structures；
Fig. 6 be in Fig. 2 A to sectional view；
Fig. 7 be in Fig. 2 B to sectional view；
Sealed structural representation when Fig. 8 is the working condition of Fig. 7；
Fig. 9 be in Fig. 2 C to sectional view；
Figure 10 is the D of box portion in Fig. 9 to sectional view；
Figure 11 is that the axle of another embodiment of the present invention surveys direction schematic diagram；
Figure 12 is the sectional view of the structure in Figure 11；
Figure 13 is the sectional view of another embodiment；
Each component names in figure：1. box body；2. lid；3. ELISA Plate placed cavity；4. ELISA Plate；5. through hole；6. cleaning needle；7. clear
Board-washing；8. escaping pipe；9. outlet pipe；10. valve；11. water inlet pipes；12. chutes；13. slide blocks；14. cleaning bottom cavities;15.
Pressure relief means thereon.
Specific embodiment
Embodiment 1：The quick board-washing machine of a kind of micro reaction plate, referring to Fig. 1 to Figure 10, including the He of box body 1 being tightly connected
The plate hole that ELISA Plate placed cavity 3 and correspondence ELISA Plate 4 are provided with lid 2, lid 2 is provided with the corresponding through hole 5 of number size,
ELISA Plate purging system is provided with box body 1 and ELISA Plate drains system；ELISA Plate purging system includes corresponding with each through hole clear
The liquid source of cleaning fluid washed shower nozzle and be connected with cleaning sprayer, specifically, including clean plate 7, the upper surface of clean plate 7 be provided with
The corresponding cleaning needle 6 of plate hole number size of ELISA Plate 4, the inner hollow of cleaning needle 6 is outer after connecting with the bottom cavity of clean plate 7
Connect the liquid source of cleaning fluid；ELISA Plate drains system to be included being arranged on board-washing machine, connects the escaping pipe 8 of tray interior and go out with this
The negative pressure source that tracheae 8 is connected, lid 2 is provided with pressure relief means thereon 15.In specific works, pressure relief means thereon 15 can be hydraulic valve,
Can also be the release element of handle type, it is intended to after the completion of negative pressure absorbing process, release is carried out to tray interior, it is convenient to beat
Open.
The pipeline for forming negative pressure source is escaping pipe 8, is arranged at the middle and lower part of the side of box body 1, is additionally provided with out in the bottom of lid 2
Water pipe 9, outlet pipe 9 is in parallel with escaping pipe 8, and valve 10 is provided with outlet pipe 9.
Cleaning sprayer is installed on clean plate, is moving sets connection between clean plate 7 and box body 1, and on clean plate 7 cunning is provided with
Block 13, the corresponding relative position in box body 1 is provided with chute 12, and the edge of clean plate 7 spacing apart between box body 1 is 5mm.
The upper surface of clean plate 7 is provided with the spherical crown shape inclined-plane for promoting current to fall.
The invention further relates to a kind of cleaning method using the board-washing machine, comprises the following steps that：
（1）Dispose and position：ELISA Plate 4 is installed on into the specified location in cleaning chamber, thereon each test hole lower section correspondence
It is provided with the delivery port of cleaning device；
（2）Cleaning：The liquid source of external cleaning fluid, a length of 5 when being carried out with hole by each test of cleaning device to ELISA Plate 4～
The cleaning of 15s, the current direction Jing lower sections outlet pipe 9 after cleaning flows out；
（3）Cleaning：Outlet pipe 9 is closed, cleaning chamber constitutes annular seal space, a length of 15s when connecting negative pressure source to carrying out in annular seal space
Air-breathing, removes moisture remaining in annular seal space.
During work, ELISA Plate micropore direction is installed into upward ELISA Plate placed cavity 3, and lid, lid and box body are overturn afterwards
Coordinate, formed and cleaned and negative pressure absorbing after sealing container, to draw out residual moisture and internal gas.Seal form can be with
For snapping, or it is hinged.In the present embodiment, box body 1 and the spiral-lock of lid 2 are in one.The contact surface of box body 1 and lid 2 sets
There is sealing strip.The cleaning process entirety time can be foreshortened to 15s by the design, meanwhile, different from centrifugal drying conventional at this stage
Upwards, method involved in the present invention plate hole in cleaning and negative inspiratory pressure is downward, it is to avoid cross-infection between plate hole for board pore.
Embodiment 2：Working method is with embodiment 1, concrete difference, such as Figure 11,12, and box body 1 and lid 2 are hinged
Connection, ELISA Plate 4 is installed into ELISA Plate placed cavity 3 with the mounting means of horizontal grafting.
Embodiment 3：Working method is with embodiment 1, concrete difference, such as Figure 13, and ELISA Plate 4 can be vertically inserting
The mounting means for connecing is installed into ELISA Plate placed cavity 3, further reduces installation difficulty：
Embodiment 4：Working method is that inclined-plane is up-small and down-big prism-frustum-shaped surface with embodiment 1, concrete difference.
Embodiment 5：Working method is that the upper surface of clean plate 7 is plane with embodiment 1, concrete difference, but its
It is provided with multiple guiding gutters for being able to and quickly guiding current to fall.
It is last it should be noted that, above person is only section Example of the present invention, and is not used to limit the present invention, according to this
Bright structure and feature, slightly modifications and winner, also should be included within the scope of the present invention.
Claims (10)
1. the quick board-washing machine of a kind of micro reaction plate, it is characterised in that：Including the box body being tightly connected（1）And lid（2）, lid
（2）Inside it is provided with ELISA Plate placed cavity（3）And correspondence ELISA Plate（4）Plate hole be provided with the corresponding through hole of number size（5）, institute
State box body（1）Inside it is provided with ELISA Plate purging system and ELISA Plate drains system；The ELISA Plate purging system includes and each through hole
The liquid source of corresponding cleaning sprayer and the cleaning fluid being connected with cleaning sprayer；The ELISA Plate drains system to be included being arranged at washing
On trigger, connection tray interior escaping pipe（8）And with the escaping pipe（8）The negative pressure source being connected, the lid（2）It is provided with
Pressure relief means thereon（15）.
2. the quick board-washing machine of micro reaction plate as claimed in claim 1, it is characterised in that：The pipeline for forming negative pressure source is outlet
Pipe（8）, it is arranged at the box body（1）The middle and lower part of side；In the lid（2）Bottom is additionally provided with outlet pipe（9）, the water outlet
Pipe（9）With the escaping pipe（8）Parallel connection, in the outlet pipe（9）It is provided with valve（10）.
3. the quick board-washing machine of micro reaction plate as claimed in claim 2, it is characterised in that：The cleaning sprayer is installed on cleaning
On plate, the clean plate（7）With the box body（1）Between for moving sets connection, in the clean plate（7）It is provided with slide block（13）,
It is corresponding in box body（1）Relative position be provided with chute（12）, clean plate（7）Edge apart from box body（1）Between spacing it is big
In 2mm.
4. the quick board-washing machine of micro reaction plate as claimed in claim 3, it is characterised in that：The clean plate（7）Upper surface
It is provided with the inclined-plane for promoting current to fall.
5. the quick board-washing machine of micro reaction plate as claimed in claim 4, it is characterised in that：The inclined-plane is ball crown surface.
6. the quick board-washing machine of micro reaction plate as claimed in claim 4, it is characterised in that：The inclined-plane is up-small and down-big rib
Mesa-shaped surface.
7. the quick board-washing machine of micro reaction plate as claimed in claim 5, it is characterised in that：The box body（1）And lid（2）Hinge
Prop up connection.
8. the quick board-washing machine of micro reaction plate as claimed in claim 5, it is characterised in that：The box body（1）And lid（2）Button
Loaded on one.
9. the quick board-washing machine of micro reaction plate as claimed in claim 7 or 8, it is characterised in that：The box body（1）And lid
（2）Contact surface be provided with sealing strip.
10. a kind of plate washing method of micro reaction plate, using board-washing machine as claimed in claim 1, it is characterised in that include as
Lower step：
（1）Dispose and position：By ELISA Plate（4）The specified location being installed in cleaning chamber, thereon each test hole lower section is right
The delivery port of cleaning device should be provided with；
（2）Cleaning：The liquid source of external cleaning fluid, by the cleaning device to ELISA Plate（4）Each test when being carried out with hole
The cleaning of a length of 5～15s, the current direction Jing lower sections outlet pipe after cleaning（9）Flow out；
（3）Cleaning：Close outlet pipe（9）, cleaning chamber composition annular seal space, a length of 5 when connection negative pressure source in annular seal space to carrying out～
The air-breathing of 55s, removes moisture remaining in annular seal space.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710084491.6A CN106623205A (en) | 2017-02-16 | 2017-02-16 | Quick plate washing machine for microporous reaction plate and plate washing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710084491.6A CN106623205A (en) | 2017-02-16 | 2017-02-16 | Quick plate washing machine for microporous reaction plate and plate washing method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106623205A true CN106623205A (en) | 2017-05-10 |
Family
ID=58846339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710084491.6A Pending CN106623205A (en) | 2017-02-16 | 2017-02-16 | Quick plate washing machine for microporous reaction plate and plate washing method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106623205A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108015040A (en) * | 2017-10-27 | 2018-05-11 | 无锡艾科瑞思产品设计与研究有限公司 | A kind of board-washing machine of leakproofness higher |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201016983Y (en) * | 2007-03-05 | 2008-02-06 | 深圳市汇松科技发展有限公司 | Improved type enzyme-labeled plate washer |
| CN202185418U (en) * | 2011-07-04 | 2012-04-11 | 崔根基 | Elisa plate horizontal type backflushing automatic wash-blow cleaning machine |
| CN202447304U (en) * | 2011-12-30 | 2012-09-26 | 洛阳理工学院 | Turnable vertical plate washer of micro-porous reaction plate |
| CN105517711A (en) * | 2013-08-06 | 2016-04-20 | 烟台澳斯邦生物工程有限公司 | Centrifuge and method for centrifuging a reaction vessel unit |
| CN106269657A (en) * | 2016-10-17 | 2017-01-04 | 浙江聚康生物工程有限公司 | What a kind of oneself dredged washes trigger |
| CN206578068U (en) * | 2017-02-16 | 2017-10-24 | 吴建国 | The quick board-washing machine of micro reaction plate |
-
2017
- 2017-02-16 CN CN201710084491.6A patent/CN106623205A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201016983Y (en) * | 2007-03-05 | 2008-02-06 | 深圳市汇松科技发展有限公司 | Improved type enzyme-labeled plate washer |
| CN202185418U (en) * | 2011-07-04 | 2012-04-11 | 崔根基 | Elisa plate horizontal type backflushing automatic wash-blow cleaning machine |
| CN202447304U (en) * | 2011-12-30 | 2012-09-26 | 洛阳理工学院 | Turnable vertical plate washer of micro-porous reaction plate |
| CN105517711A (en) * | 2013-08-06 | 2016-04-20 | 烟台澳斯邦生物工程有限公司 | Centrifuge and method for centrifuging a reaction vessel unit |
| CN106269657A (en) * | 2016-10-17 | 2017-01-04 | 浙江聚康生物工程有限公司 | What a kind of oneself dredged washes trigger |
| CN206578068U (en) * | 2017-02-16 | 2017-10-24 | 吴建国 | The quick board-washing machine of micro reaction plate |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108015040A (en) * | 2017-10-27 | 2018-05-11 | 无锡艾科瑞思产品设计与研究有限公司 | A kind of board-washing machine of leakproofness higher |
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| PB01 | Publication | ||
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Application publication date: 20170510 |